LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Imatinib | 10 | uM | LJP6 | 3 | N13 | 72 | hr | 2543 | 5677 | 5557 | 1.0215 | 1.0381 |
| SK-BR-3 | NVP-TAE684 | 0.04 | uM | LJP6 | 1 | K18 | 72 | hr | 2543 | 5616 | 5258 | 1.0679 | 1.1294 |
| SK-BR-3 | NVP-TAE684 | 0.04 | uM | LJP6 | 2 | K18 | 72 | hr | 2543 | 5762 | 5438 | 1.0596 | 1.1084 |
| SK-BR-3 | NVP-TAE684 | 0.04 | uM | LJP6 | 3 | K18 | 72 | hr | 2543 | 5754 | 5557 | 1.0354 | 1.0626 |
| SK-BR-3 | NVP-TAE684 | 0.12 | uM | LJP6 | 1 | K17 | 72 | hr | 2543 | 4371 | 5258 | 0.8312 | 0.6765 |
| SK-BR-3 | NVP-TAE684 | 0.12 | uM | LJP6 | 2 | K17 | 72 | hr | 2543 | 4511 | 5438 | 0.8295 | 0.6865 |
| SK-BR-3 | NVP-TAE684 | 0.12 | uM | LJP6 | 3 | K17 | 72 | hr | 2543 | 4664 | 5557 | 0.8393 | 0.7121 |
| SK-BR-3 | NVP-TAE684 | 0.37 | uM | LJP6 | 1 | K16 | 72 | hr | 2543 | 5288 | 5258 | 1.0055 | 1.0106 |
| SK-BR-3 | NVP-TAE684 | 0.37 | uM | LJP6 | 2 | K16 | 72 | hr | 2543 | 5305 | 5438 | 0.9755 | 0.9553 |
| SK-BR-3 | NVP-TAE684 | 0.37 | uM | LJP6 | 3 | K16 | 72 | hr | 2543 | 5656 | 5557 | 1.0177 | 1.0315 |
| SK-BR-3 | NVP-TAE684 | 1.11 | uM | LJP6 | 1 | K15 | 72 | hr | 2543 | 4648 | 5258 | 0.8838 | 0.7777 |
| SK-BR-3 | NVP-TAE684 | 1.11 | uM | LJP6 | 2 | K15 | 72 | hr | 2543 | 4661 | 5438 | 0.8571 | 0.7376 |
| SK-BR-3 | NVP-TAE684 | 1.11 | uM | LJP6 | 3 | K15 | 72 | hr | 2543 | 5092 | 5557 | 0.9163 | 0.8508 |
| SK-BR-3 | NVP-TAE684 | 3.33 | uM | LJP6 | 1 | K14 | 72 | hr | 2543 | 2949 | 5258 | 0.5608 | 0.1516 |
| SK-BR-3 | NVP-TAE684 | 3.33 | uM | LJP6 | 2 | K14 | 72 | hr | 2543 | 2622 | 5438 | 0.4822 | 0.0281 |
| SK-BR-3 | NVP-TAE684 | 3.33 | uM | LJP6 | 3 | K14 | 72 | hr | 2543 | 3187 | 5557 | 0.5735 | 0.2214 |
| SK-BR-3 | NVP-TAE684 | 10 | uM | LJP6 | 1 | K13 | 72 | hr | 2543 | 1957 | 5258 | 0.3721 | -0.2213 |
| SK-BR-3 | NVP-TAE684 | 10 | uM | LJP6 | 2 | K13 | 72 | hr | 2543 | 2186 | 5438 | 0.4020 | -0.1290 |
| SK-BR-3 | NVP-TAE684 | 10 | uM | LJP6 | 3 | K13 | 72 | hr | 2543 | 2226 | 5557 | 0.4006 | -0.1115 |
| SK-BR-3 | CGP60474 | 0.04 | uM | LJP6 | 1 | G06 | 72 | hr | 2543 | 1313 | 5258 | 0.2497 | -0.4679 |
| SK-BR-3 | CGP60474 | 0.04 | uM | LJP6 | 2 | G06 | 72 | hr | 2543 | 1435 | 5438 | 0.2639 | -0.4067 |
| SK-BR-3 | CGP60474 | 0.04 | uM | LJP6 | 3 | G06 | 72 | hr | 2543 | 1518 | 5557 | 0.2732 | -0.3673 |
| SK-BR-3 | CGP60474 | 0.04 | uM | LJP5 | 1 | F06 | 72 | hr | 2543 | 5707 | 5734 | 0.9952 | 0.9918 |
| SK-BR-3 | CGP60474 | 0.04 | uM | LJP5 | 2 | F06 | 72 | hr | 2543 | 5829 | 5761 | 1.0117 | 1.0199 |
| SK-BR-3 | CGP60474 | 0.04 | uM | LJP5 | 3 | F06 | 72 | hr | 2543 | 5872 | 5760 | 1.0193 | 1.0327 |