LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PLX-4720
0.37
uM
LJP5
 2
K04
 72
hr
 1694 10686 11099 0.9628 0.9722
MCF 10A PLX-4720
0.37
uM
LJP5
 3
K04
 72
hr
 1694 10751 11168 0.9626 0.9722
MCF 10A PLX-4720
1.11
uM
LJP5
 1
K03
 72
hr
 1694 11891 11042 1.0769 1.0555
MCF 10A PLX-4720
1.11
uM
LJP5
 2
K03
 72
hr
 1694 11236 11099 1.0123 1.0090
MCF 10A PLX-4720
1.11
uM
LJP5
 3
K03
 72
hr
 1694 11624 11168 1.0408 1.0296
MCF 10A PLX-4720
3.33
uM
LJP5
 1
K02
 72
hr
 1694 12047 11042 1.0910 1.0654
MCF 10A PLX-4720
3.33
uM
LJP5
 2
K02
 72
hr
 1694 11840 11099 1.0667 1.0482
MCF 10A PLX-4720
3.33
uM
LJP5
 3
K02
 72
hr
 1694 12217 11168 1.0939 1.0671
MCF 10A PLX-4720
10
uM
LJP5
 1
K01
 72
hr
 1694 9603 11042 0.8697 0.8993
MCF 10A PLX-4720
10
uM
LJP5
 2
K01
 72
hr
 1694 10964 11099 0.9878 0.9910
MCF 10A PLX-4720
10
uM
LJP5
 3
K01
 72
hr
 1694 10377 11168 0.9291 0.9467
MCF 10A Lapatinib
0.04
uM
LJP6
 1
M24
 72
hr
 1694 10919 11220 0.9731 0.9801
MCF 10A Lapatinib
0.04
uM
LJP6
 2
M24
 72
hr
 1694 10957 11309 0.9688 0.9770
MCF 10A Lapatinib
0.04
uM
LJP6
 3
M24
 72
hr
 1694 10656 11121 0.9582 0.9688
MCF 10A Lapatinib
0.12
uM
LJP6
 1
M23
 72
hr
 1694 10396 11220 0.9265 0.9448
MCF 10A Lapatinib
0.12
uM
LJP6
 2
M23
 72
hr
 1694 10534 11309 0.9314 0.9488
MCF 10A Lapatinib
0.12
uM
LJP6
 3
M23
 72
hr
 1694 10392 11121 0.9344 0.9507
MCF 10A Lapatinib
0.37
uM
LJP6
 1
M22
 72
hr
 1694 10064 11220 0.8969 0.9218
MCF 10A Lapatinib
0.37
uM
LJP6
 2
M22
 72
hr
 1694 10046 11309 0.8883 0.9153
MCF 10A Lapatinib
0.37
uM
LJP6
 3
M22
 72
hr
 1694 10176 11121 0.9150 0.9356
MCF 10A Lapatinib
1.11
uM
LJP6
 1
M21
 72
hr
 1694 9541 11220 0.8503 0.8845
MCF 10A Lapatinib
1.11
uM
LJP6
 2
M21
 72
hr
 1694 9676 11309 0.8556 0.8893
MCF 10A Lapatinib
1.11
uM
LJP6
 3
M21
 72
hr
 1694 9599 11121 0.8631 0.8944
MCF 10A Lapatinib
3.33
uM
LJP6
 1
M20
 72
hr
 1694 8232 11220 0.7336 0.7853
MCF 10A Lapatinib
3.33
uM
LJP6
 2
M20
 72
hr
 1694 8562 11309 0.7571 0.8068