LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T PI103
10
uM
LJP6
 2
I13
 72
hr
 765 680 3095 0.2197 -0.0568
Hs 578T PI103
10
uM
LJP6
 3
I13
 72
hr
 765 693 3066 0.2260 -0.0482
Hs 578T Dovitinib
0.04
uM
LJP5
 1
E24
 72
hr
 765 2540 3140 0.8088 0.8022
Hs 578T Dovitinib
0.04
uM
LJP5
 2
E24
 72
hr
 765 2499 3151 0.7929 0.7852
Hs 578T Dovitinib
0.04
uM
LJP5
 3
E24
 72
hr
 765 2396 3152 0.7601 0.7486
Hs 578T Dovitinib
0.12
uM
LJP5
 1
E23
 72
hr
 765 1932 3140 0.6152 0.5757
Hs 578T Dovitinib
0.12
uM
LJP5
 2
E23
 72
hr
 765 1914 3151 0.6073 0.5667
Hs 578T Dovitinib
0.12
uM
LJP5
 3
E23
 72
hr
 765 1723 3152 0.5466 0.4880
Hs 578T Dovitinib
0.37
uM
LJP5
 1
E22
 72
hr
 765 1305 3140 0.4156 0.2997
Hs 578T Dovitinib
0.37
uM
LJP5
 2
E22
 72
hr
 765 1270 3151 0.4030 0.2817
Hs 578T Dovitinib
0.37
uM
LJP5
 3
E22
 72
hr
 765 1300 3152 0.4124 0.2963
Hs 578T Dovitinib
1.11
uM
LJP5
 1
E21
 72
hr
 765 1257 3140 0.4003 0.2760
Hs 578T Dovitinib
1.11
uM
LJP5
 2
E21
 72
hr
 765 1134 3151 0.3598 0.2125
Hs 578T Dovitinib
1.11
uM
LJP5
 3
E21
 72
hr
 765 1198 3152 0.3800 0.2455
Hs 578T Dovitinib
3.33
uM
LJP5
 1
E20
 72
hr
 765 1135 3140 0.3614 0.2136
Hs 578T Dovitinib
3.33
uM
LJP5
 2
E20
 72
hr
 765 1221 3151 0.3874 0.2572
Hs 578T Dovitinib
3.33
uM
LJP5
 3
E20
 72
hr
 765 1064 3152 0.3375 0.1752
Hs 578T Dovitinib
10
uM
LJP5
 1
E19
 72
hr
 765 1144 3140 0.3643 0.2183
Hs 578T Dovitinib
10
uM
LJP5
 2
E19
 72
hr
 765 1061 3151 0.3367 0.1736
Hs 578T Dovitinib
10
uM
LJP5
 3
E19
 72
hr
 765 1268 3152 0.4022 0.2806
Hs 578T GSK 690693
0.04
uM
LJP5
 1
F24
 72
hr
 765 2581 3140 0.8219 0.8164
Hs 578T GSK 690693
0.04
uM
LJP5
 2
F24
 72
hr
 765 2752 3151 0.8732 0.8715
Hs 578T GSK 690693
0.04
uM
LJP5
 3
F24
 72
hr
 765 2828 3152 0.8971 0.8965
Hs 578T GSK 690693
0.12
uM
LJP5
 1
F23
 72
hr
 765 2448 3140 0.7795 0.7699
Hs 578T GSK 690693
0.12
uM
LJP5
 2
F23
 72
hr
 765 2469 3151 0.7834 0.7747