LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Trametinib
3.33
uM
LJP5
 1
P20
 72
hr
 1334 2980 3930 0.7581 0.6744
BT-20 Trametinib
3.33
uM
LJP5
 2
P20
 72
hr
 1334 3314 4051 0.8181 0.7643
BT-20 Trametinib
3.33
uM
LJP5
 3
P20
 72
hr
 1334 3025 4117 0.7346 0.6544
BT-20 Trametinib
10
uM
LJP5
 1
P19
 72
hr
 1334 3344 3930 0.8507 0.8029
BT-20 Trametinib
10
uM
LJP5
 2
P19
 72
hr
 1334 3662 4051 0.9040 0.8778
BT-20 Trametinib
10
uM
LJP5
 3
P19
 72
hr
 1334 3570 4117 0.8670 0.8319
BT-20 Omipalisib
0.04
uM
LJP6
 1
N06
 72
hr
 1334 1212 3955 0.3064 -0.0597
BT-20 Omipalisib
0.04
uM
LJP6
 2
N06
 72
hr
 1334 1167 3899 0.2993 -0.0831
BT-20 Omipalisib
0.04
uM
LJP6
 3
N06
 72
hr
 1334 1159 3921 0.2956 -0.0868
BT-20 Omipalisib
0.12
uM
LJP6
 1
N05
 72
hr
 1334 1009 3955 0.2551 -0.1634
BT-20 Omipalisib
0.12
uM
LJP6
 2
N05
 72
hr
 1334 1084 3899 0.2780 -0.1259
BT-20 Omipalisib
0.12
uM
LJP6
 3
N05
 72
hr
 1334 1043 3921 0.2660 -0.1467
BT-20 Omipalisib
0.37
uM
LJP6
 1
N04
 72
hr
 1334 843 3955 0.2131 -0.2541
BT-20 Omipalisib
0.37
uM
LJP6
 2
N04
 72
hr
 1334 901 3899 0.2311 -0.2244
BT-20 Omipalisib
0.37
uM
LJP6
 3
N04
 72
hr
 1334 824 3921 0.2101 -0.2667
BT-20 Omipalisib
1.11
uM
LJP6
 1
N03
 72
hr
 1334 879 3955 0.2222 -0.2339
BT-20 Omipalisib
1.11
uM
LJP6
 2
N03
 72
hr
 1334 614 3899 0.1575 -0.3947
BT-20 Omipalisib
1.11
uM
LJP6
 3
N03
 72
hr
 1334 710 3921 0.1811 -0.3337
BT-20 Omipalisib
3.33
uM
LJP6
 1
N02
 72
hr
 1334 665 3955 0.1681 -0.3588
BT-20 Omipalisib
3.33
uM
LJP6
 2
N02
 72
hr
 1334 539 3899 0.1382 -0.4436
BT-20 Omipalisib
3.33
uM
LJP6
 3
N02
 72
hr
 1334 494 3921 0.1260 -0.4723
BT-20 Omipalisib
10
uM
LJP6
 1
N01
 72
hr
 1334 520 3955 0.1315 -0.4519
BT-20 Omipalisib
10
uM
LJP6
 2
N01
 72
hr
 1334 430 3899 0.1103 -0.5192
BT-20 Omipalisib
10
uM
LJP6
 3
N01
 72
hr
 1334 488 3921 0.1245 -0.4764
BT-20 Buparlisib
0.04
uM
LJP5
 1
H06
 72
hr
 1334 3947 3930 1.0041 1.0053