LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Fedratinib
0.12
uM
LJP5
 3
L05
 72
hr
 1334 3939 4117 0.9566 0.9462
BT-20 Fedratinib
0.37
uM
LJP5
 1
L04
 72
hr
 1334 3872 3930 0.9850 0.9808
BT-20 Fedratinib
0.37
uM
LJP5
 2
L04
 72
hr
 1334 3782 4051 0.9336 0.9160
BT-20 Fedratinib
0.37
uM
LJP5
 3
L04
 72
hr
 1334 4012 4117 0.9743 0.9683
BT-20 Fedratinib
1.11
uM
LJP5
 1
L03
 72
hr
 1334 3541 3930 0.9008 0.8704
BT-20 Fedratinib
1.11
uM
LJP5
 2
L03
 72
hr
 1334 3634 4051 0.8971 0.8688
BT-20 Fedratinib
1.11
uM
LJP5
 3
L03
 72
hr
 1334 3509 4117 0.8522 0.8126
BT-20 Fedratinib
3.33
uM
LJP5
 1
L02
 72
hr
 1334 2900 3930 0.7378 0.6454
BT-20 Fedratinib
3.33
uM
LJP5
 2
L02
 72
hr
 1334 2937 4051 0.7250 0.6362
BT-20 Fedratinib
3.33
uM
LJP5
 3
L02
 72
hr
 1334 3122 4117 0.7582 0.6868
BT-20 Fedratinib
10
uM
LJP5
 1
L01
 72
hr
 1334 749 3930 0.1906 -0.3098
BT-20 Fedratinib
10
uM
LJP5
 2
L01
 72
hr
 1334 919 4051 0.2269 -0.2078
BT-20 Fedratinib
10
uM
LJP5
 3
L01
 72
hr
 1334 858 4117 0.2084 -0.2380
BT-20 Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 1334 3109 3930 0.7909 0.7205
BT-20 Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 1334 2925 4051 0.7220 0.6320
BT-20 Trametinib
0.04
uM
LJP5
 3
P24
 72
hr
 1334 3431 4117 0.8332 0.7877
BT-20 Trametinib
0.12
uM
LJP5
 1
P23
 72
hr
 1334 3410 3930 0.8675 0.8257
BT-20 Trametinib
0.12
uM
LJP5
 2
P23
 72
hr
 1334 3652 4051 0.9015 0.8746
BT-20 Trametinib
0.12
uM
LJP5
 3
P23
 72
hr
 1334 3495 4117 0.8488 0.8081
BT-20 Trametinib
0.37
uM
LJP5
 1
P22
 72
hr
 1334 3231 3930 0.8220 0.7636
BT-20 Trametinib
0.37
uM
LJP5
 2
P22
 72
hr
 1334 3368 4051 0.8314 0.7822
BT-20 Trametinib
0.37
uM
LJP5
 3
P22
 72
hr
 1334 3578 4117 0.8689 0.8344
BT-20 Trametinib
1.11
uM
LJP5
 1
P21
 72
hr
 1334 3285 3930 0.8357 0.7824
BT-20 Trametinib
1.11
uM
LJP5
 2
P21
 72
hr
 1334 3364 4051 0.8304 0.7809
BT-20 Trametinib
1.11
uM
LJP5
 3
P21
 72
hr
 1334 3294 4117 0.8000 0.7434