LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 3 | C16 | 72 | hr | 1389 | 6082 | 6038 | 1.0072 | 1.0068 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 1 | C15 | 72 | hr | 1389 | 6265 | 5772 | 1.0853 | 1.0813 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 3 | C15 | 72 | hr | 1389 | 6261 | 6038 | 1.0368 | 1.0344 |
| MCF7 | Vemurafenib | 3.33 | uM | LJP5 | 1 | C14 | 72 | hr | 1389 | 6170 | 5772 | 1.0689 | 1.0659 |
| MCF7 | Vemurafenib | 3.33 | uM | LJP5 | 3 | C14 | 72 | hr | 1389 | 5685 | 6038 | 0.9415 | 0.9439 |
| MCF7 | Vemurafenib | 10 | uM | LJP5 | 1 | C13 | 72 | hr | 1389 | 5571 | 5772 | 0.9651 | 0.9657 |
| MCF7 | Vemurafenib | 10 | uM | LJP5 | 3 | C13 | 72 | hr | 1389 | 5666 | 6038 | 0.9383 | 0.9408 |
| MCF7 | Enzastaurin | 0.04 | uM | LJP5 | 1 | D18 | 72 | hr | 1389 | 5951 | 5772 | 1.0309 | 1.0299 |
| MCF7 | Enzastaurin | 0.04 | uM | LJP5 | 3 | D18 | 72 | hr | 1389 | 6328 | 6038 | 1.0479 | 1.0447 |
| MCF7 | Enzastaurin | 0.12 | uM | LJP5 | 1 | D17 | 72 | hr | 1389 | 5937 | 5772 | 1.0285 | 1.0275 |
| MCF7 | Enzastaurin | 0.12 | uM | LJP5 | 3 | D17 | 72 | hr | 1389 | 5791 | 6038 | 0.9590 | 0.9609 |
| MCF7 | Enzastaurin | 0.37 | uM | LJP5 | 1 | D16 | 72 | hr | 1389 | 5794 | 5772 | 1.0037 | 1.0036 |
| MCF7 | Enzastaurin | 0.37 | uM | LJP5 | 3 | D16 | 72 | hr | 1389 | 6456 | 6038 | 1.0691 | 1.0641 |
| MCF7 | Enzastaurin | 1.11 | uM | LJP5 | 1 | D15 | 72 | hr | 1389 | 5556 | 5772 | 0.9625 | 0.9631 |
| MCF7 | Enzastaurin | 1.11 | uM | LJP5 | 3 | D15 | 72 | hr | 1389 | 6129 | 6038 | 1.0150 | 1.0141 |
| MCF7 | Enzastaurin | 3.33 | uM | LJP5 | 1 | D14 | 72 | hr | 1389 | 5661 | 5772 | 0.9807 | 0.9811 |
| MCF7 | Enzastaurin | 3.33 | uM | LJP5 | 3 | D14 | 72 | hr | 1389 | 6480 | 6038 | 1.0731 | 1.0677 |
| MCF7 | Enzastaurin | 10 | uM | LJP5 | 1 | D13 | 72 | hr | 1389 | 5951 | 5772 | 1.0309 | 1.0299 |
| MCF7 | Enzastaurin | 10 | uM | LJP5 | 3 | D13 | 72 | hr | 1389 | 6194 | 6038 | 1.0258 | 1.0241 |
| MCF7 | Palbociclib | 0.04 | uM | LJP6 | 1 | E18 | 72 | hr | 1389 | 3883 | 5147 | 0.7544 | 0.7229 |
| MCF7 | Palbociclib | 0.04 | uM | LJP6 | 2 | E18 | 72 | hr | 1389 | 4785 | 5447 | 0.8783 | 0.8726 |
| MCF7 | Palbociclib | 0.04 | uM | LJP6 | 3 | E18 | 72 | hr | 1389 | 4534 | 5740 | 0.7898 | 0.7823 |
| MCF7 | Palbociclib | 0.12 | uM | LJP6 | 1 | E17 | 72 | hr | 1389 | 3594 | 5147 | 0.6983 | 0.6538 |
| MCF7 | Palbociclib | 0.12 | uM | LJP6 | 2 | E17 | 72 | hr | 1389 | 4010 | 5447 | 0.7361 | 0.7121 |
| MCF7 | Palbociclib | 0.12 | uM | LJP6 | 3 | E17 | 72 | hr | 1389 | 4251 | 5740 | 0.7405 | 0.7270 |