LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | WYE-125132 | 1.11 | uM | LJP6 | 2 | L09 | 72 | hr | 1389 | 1862 | 5447 | 0.3418 | 0.1602 |
| MCF7 | WYE-125132 | 1.11 | uM | LJP6 | 3 | L09 | 72 | hr | 1389 | 1867 | 5740 | 0.3252 | 0.1554 |
| MCF7 | WYE-125132 | 3.33 | uM | LJP6 | 1 | L08 | 72 | hr | 1389 | 1654 | 5147 | 0.3214 | 0.0968 |
| MCF7 | WYE-125132 | 3.33 | uM | LJP6 | 2 | L08 | 72 | hr | 1389 | 1746 | 5447 | 0.3205 | 0.1230 |
| MCF7 | WYE-125132 | 3.33 | uM | LJP6 | 3 | L08 | 72 | hr | 1389 | 1704 | 5740 | 0.2968 | 0.1050 |
| MCF7 | WYE-125132 | 10 | uM | LJP6 | 1 | L07 | 72 | hr | 1389 | 1646 | 5147 | 0.3198 | 0.0940 |
| MCF7 | WYE-125132 | 10 | uM | LJP6 | 2 | L07 | 72 | hr | 1389 | 1645 | 5447 | 0.3020 | 0.0896 |
| MCF7 | WYE-125132 | 10 | uM | LJP6 | 3 | L07 | 72 | hr | 1389 | 1665 | 5740 | 0.2900 | 0.0926 |
| MCF7 | Barasertib | 0.04 | uM | LJP5 | 1 | D12 | 72 | hr | 1389 | 2191 | 5772 | 0.3796 | 0.2483 |
| MCF7 | Barasertib | 0.04 | uM | LJP5 | 3 | D12 | 72 | hr | 1389 | 2277 | 6038 | 0.3771 | 0.2625 |
| MCF7 | Barasertib | 0.12 | uM | LJP5 | 1 | D11 | 72 | hr | 1389 | 1785 | 5772 | 0.3092 | 0.1298 |
| MCF7 | Barasertib | 0.12 | uM | LJP5 | 3 | D11 | 72 | hr | 1389 | 1808 | 6038 | 0.2994 | 0.1324 |
| MCF7 | Barasertib | 0.37 | uM | LJP5 | 1 | D10 | 72 | hr | 1389 | 1652 | 5772 | 0.2862 | 0.0880 |
| MCF7 | Barasertib | 0.37 | uM | LJP5 | 3 | D10 | 72 | hr | 1389 | 1723 | 6038 | 0.2853 | 0.1070 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 1 | D09 | 72 | hr | 1389 | 1710 | 5772 | 0.2962 | 0.1064 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 3 | D09 | 72 | hr | 1389 | 1918 | 6038 | 0.3176 | 0.1644 |
| MCF7 | Barasertib | 3.33 | uM | LJP5 | 1 | D08 | 72 | hr | 1389 | 1604 | 5772 | 0.2779 | 0.0725 |
| MCF7 | Barasertib | 3.33 | uM | LJP5 | 3 | D08 | 72 | hr | 1389 | 1874 | 6038 | 0.3103 | 0.1517 |
| MCF7 | Barasertib | 10 | uM | LJP5 | 1 | D07 | 72 | hr | 1389 | 1698 | 5772 | 0.2942 | 0.1027 |
| MCF7 | Barasertib | 10 | uM | LJP5 | 3 | D07 | 72 | hr | 1389 | 1629 | 6038 | 0.2698 | 0.0781 |
| MCF7 | Vemurafenib | 0.04 | uM | LJP5 | 1 | C18 | 72 | hr | 1389 | 5662 | 5772 | 0.9809 | 0.9813 |
| MCF7 | Vemurafenib | 0.04 | uM | LJP5 | 3 | C18 | 72 | hr | 1389 | 5984 | 6038 | 0.9910 | 0.9915 |
| MCF7 | Vemurafenib | 0.12 | uM | LJP5 | 1 | C17 | 72 | hr | 1389 | 5926 | 5772 | 1.0266 | 1.0257 |
| MCF7 | Vemurafenib | 0.12 | uM | LJP5 | 3 | C17 | 72 | hr | 1389 | 5892 | 6038 | 0.9757 | 0.9770 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 1 | C16 | 72 | hr | 1389 | 6222 | 5772 | 1.0779 | 1.0743 |