LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 2
G16
 72
hr
 1311 4127 4961 0.8318 0.8170
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 3
G16
 72
hr
 1311 3521 4973 0.7079 0.6711
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 1
G16
 72
hr
 1311 4232 5128 0.8252 0.8139
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 2
G16
 72
hr
 1311 4537 5100 0.8896 0.8841
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 3
G16
 72
hr
 1311 4187 5010 0.8356 0.8226
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 1
G15
 72
hr
 1311 1289 4870 0.2647 -0.0092
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 2
G15
 72
hr
 1311 1386 4961 0.2793 0.0291
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 3
G15
 72
hr
 1311 1212 4973 0.2437 -0.0403
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 1
G15
 72
hr
 1311 1243 5128 0.2424 -0.0270
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 2
G15
 72
hr
 1311 1400 5100 0.2745 0.0338
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 3
G15
 72
hr
 1311 1511 5010 0.3016 0.0759
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 1
G14
 72
hr
 1311 821 4870 0.1686 -0.2193
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 2
G14
 72
hr
 1311 881 4961 0.1776 -0.1873
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 3
G14
 72
hr
 1311 729 4973 0.1466 -0.2632
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 1
G14
 72
hr
 1311 1051 5128 0.2049 -0.1065
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 2
G14
 72
hr
 1311 999 5100 0.1959 -0.1298
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 3
G14
 72
hr
 1311 1062 5010 0.2119 -0.1035
MDA-MB-231 Withaferin A
10
uM
LJP6
 1
G13
 72
hr
 1311 494 4870 0.1014 -0.4031
MDA-MB-231 Withaferin A
10
uM
LJP6
 2
G13
 72
hr
 1311 335 4961 0.0675 -0.5089
MDA-MB-231 Withaferin A
10
uM
LJP6
 3
G13
 72
hr
 1311 309 4973 0.0621 -0.5285
MDA-MB-231 Withaferin A
10
uM
LJP5
 1
G13
 72
hr
 1311 561 5128 0.1094 -0.3507
MDA-MB-231 Withaferin A
10
uM
LJP5
 2
G13
 72
hr
 1311 456 5100 0.0894 -0.4169
MDA-MB-231 Withaferin A
10
uM
LJP5
 3
G13
 72
hr
 1311 381 5010 0.0760 -0.4724
MDA-MB-231
LJP6
 1
A03
 72
hr
 1311 4390 4870 0.9014 0.8933
MDA-MB-231
LJP6
 1
A04
 72
hr
 1311 4718 4870 0.9688 0.9667