LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 2
B23
 72
hr
 1311 4628 5100 0.9075 0.9033
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 3
B23
 72
hr
 1311 4515 5010 0.9010 0.8951
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 1
B22
 72
hr
 1311 4773 5128 0.9307 0.9283
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 2
B22
 72
hr
 1311 4922 5100 0.9651 0.9641
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 3
B22
 72
hr
 1311 4570 5010 0.9120 0.9070
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 1
B21
 72
hr
 1311 4225 5128 0.8239 0.8124
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 2
B21
 72
hr
 1311 4566 5100 0.8953 0.8902
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 3
B21
 72
hr
 1311 4250 5010 0.8482 0.8367
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 1
B20
 72
hr
 1311 4673 5128 0.9112 0.9077
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 2
B20
 72
hr
 1311 4717 5100 0.9249 0.9219
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 3
B20
 72
hr
 1311 4324 5010 0.8629 0.8532
MDA-MB-231 Sigma A6730
10
uM
LJP5
 1
B19
 72
hr
 1311 3771 5128 0.7353 0.7106
MDA-MB-231 Sigma A6730
10
uM
LJP5
 2
B19
 72
hr
 1311 3744 5100 0.7341 0.7081
MDA-MB-231 Sigma A6730
10
uM
LJP5
 3
B19
 72
hr
 1311 3394 5010 0.6773 0.6350
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 1
O12
 72
hr
 1311 4590 5128 0.8950 0.8904
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 2
O12
 72
hr
 1311 3948 5100 0.7741 0.7550
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 3
O12
 72
hr
 1311 4630 5010 0.9240 0.9199
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 1
O11
 72
hr
 1311 3516 5128 0.6856 0.6508
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 2
O11
 72
hr
 1311 2810 5100 0.5510 0.4753
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 3
O11
 72
hr
 1311 3413 5010 0.6811 0.6398
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 1
O10
 72
hr
 1311 2910 5128 0.5674 0.4994
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 2
O10
 72
hr
 1311 2660 5100 0.5216 0.4346
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 3
O10
 72
hr
 1311 2752 5010 0.5492 0.4670
MDA-MB-231 WH-4-025
1.11
uM
LJP5
 1
O09
 72
hr
 1311 1752 5128 0.3416 0.1585
MDA-MB-231 WH-4-025
1.11
uM
LJP5
 2
O09
 72
hr
 1311 1373 5100 0.2692 0.0236