LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Dasatinib | 10 | uM | LJP5 | 1 | D01 | 72 | hr | 1389 | 1110 | 5772 | 0.1923 | -0.1034 |
| MCF7 | Dasatinib | 10 | uM | LJP5 | 3 | D01 | 72 | hr | 1389 | 1226 | 6038 | 0.2030 | -0.0572 |
| MCF7 | Tozasertib | 0.04 | uM | LJP5 | 1 | B18 | 72 | hr | 1389 | 1596 | 5772 | 0.2765 | 0.0699 |
| MCF7 | Tozasertib | 0.04 | uM | LJP5 | 3 | B18 | 72 | hr | 1389 | 1524 | 6038 | 0.2524 | 0.0447 |
| MCF7 | Tozasertib | 0.12 | uM | LJP5 | 1 | B17 | 72 | hr | 1389 | 1499 | 5772 | 0.2597 | 0.0378 |
| MCF7 | Tozasertib | 0.12 | uM | LJP5 | 3 | B17 | 72 | hr | 1389 | 1530 | 6038 | 0.2534 | 0.0466 |
| MCF7 | Tozasertib | 0.37 | uM | LJP5 | 1 | B16 | 72 | hr | 1389 | 1516 | 5772 | 0.2626 | 0.0435 |
| MCF7 | Tozasertib | 0.37 | uM | LJP5 | 3 | B16 | 72 | hr | 1389 | 1399 | 6038 | 0.2317 | 0.0034 |
| MCF7 | Tozasertib | 1.11 | uM | LJP5 | 1 | B15 | 72 | hr | 1389 | 1523 | 5772 | 0.2638 | 0.0458 |
| MCF7 | Tozasertib | 1.11 | uM | LJP5 | 3 | B15 | 72 | hr | 1389 | 1730 | 6038 | 0.2865 | 0.1091 |
| MCF7 | Tozasertib | 3.33 | uM | LJP5 | 1 | B14 | 72 | hr | 1389 | 1472 | 5772 | 0.2550 | 0.0286 |
| MCF7 | Tozasertib | 3.33 | uM | LJP5 | 3 | B14 | 72 | hr | 1389 | 1589 | 6038 | 0.2631 | 0.0655 |
| MCF7 | Tozasertib | 10 | uM | LJP5 | 1 | B13 | 72 | hr | 1389 | 1451 | 5772 | 0.2514 | 0.0215 |
| MCF7 | Tozasertib | 10 | uM | LJP5 | 3 | B13 | 72 | hr | 1389 | 1622 | 6038 | 0.2686 | 0.0759 |
| MCF7 | Imatinib | 0.04 | uM | LJP6 | 1 | N18 | 72 | hr | 1389 | 5897 | 5147 | 1.1457 | 1.1493 |
| MCF7 | Imatinib | 0.04 | uM | LJP6 | 2 | N18 | 72 | hr | 1389 | 6052 | 5447 | 1.1109 | 1.1096 |
| MCF7 | Imatinib | 0.04 | uM | LJP6 | 3 | N18 | 72 | hr | 1389 | 6001 | 5740 | 1.0454 | 1.0438 |
| MCF7 | Imatinib | 0.12 | uM | LJP6 | 1 | N17 | 72 | hr | 1389 | 6008 | 5147 | 1.1673 | 1.1706 |
| MCF7 | Imatinib | 0.12 | uM | LJP6 | 2 | N17 | 72 | hr | 1389 | 6614 | 5447 | 1.2140 | 1.2068 |
| MCF7 | Imatinib | 0.12 | uM | LJP6 | 3 | N17 | 72 | hr | 1389 | 6090 | 5740 | 1.0609 | 1.0586 |
| MCF7 | Imatinib | 0.37 | uM | LJP6 | 1 | N16 | 72 | hr | 1389 | 5699 | 5147 | 1.1072 | 1.1108 |
| MCF7 | Imatinib | 0.37 | uM | LJP6 | 2 | N16 | 72 | hr | 1389 | 5416 | 5447 | 0.9941 | 0.9941 |
| MCF7 | Imatinib | 0.37 | uM | LJP6 | 3 | N16 | 72 | hr | 1389 | 6289 | 5740 | 1.0955 | 1.0912 |
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 1 | N15 | 72 | hr | 1389 | 5787 | 5147 | 1.1243 | 1.1280 |
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 2 | N15 | 72 | hr | 1389 | 6059 | 5447 | 1.1122 | 1.1108 |