LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 3 | N15 | 72 | hr | 1389 | 5876 | 5740 | 1.0236 | 1.0229 |
| MCF7 | Imatinib | 3.33 | uM | LJP6 | 1 | N14 | 72 | hr | 1389 | 6088 | 5147 | 1.1828 | 1.1858 |
| MCF7 | Imatinib | 3.33 | uM | LJP6 | 2 | N14 | 72 | hr | 1389 | 5731 | 5447 | 1.0520 | 1.0521 |
| MCF7 | Imatinib | 3.33 | uM | LJP6 | 3 | N14 | 72 | hr | 1389 | 5733 | 5740 | 0.9987 | 0.9987 |
| MCF7 | Imatinib | 10 | uM | LJP6 | 1 | N13 | 72 | hr | 1389 | 4950 | 5147 | 0.9617 | 0.9591 |
| MCF7 | Imatinib | 10 | uM | LJP6 | 2 | N13 | 72 | hr | 1389 | 5036 | 5447 | 0.9244 | 0.9218 |
| MCF7 | Imatinib | 10 | uM | LJP6 | 3 | N13 | 72 | hr | 1389 | 4942 | 5740 | 0.8609 | 0.8589 |
| MCF7 | NVP-TAE684 | 0.04 | uM | LJP6 | 1 | K18 | 72 | hr | 1389 | 3856 | 5147 | 0.7492 | 0.7166 |
| MCF7 | NVP-TAE684 | 0.04 | uM | LJP6 | 2 | K18 | 72 | hr | 1389 | 4569 | 5447 | 0.8387 | 0.8293 |
| MCF7 | NVP-TAE684 | 0.04 | uM | LJP6 | 3 | K18 | 72 | hr | 1389 | 4508 | 5740 | 0.7853 | 0.7773 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 1 | K17 | 72 | hr | 1389 | 2250 | 5147 | 0.4371 | 0.2908 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 2 | K17 | 72 | hr | 1389 | 2111 | 5447 | 0.3875 | 0.2365 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 3 | K17 | 72 | hr | 1389 | 2426 | 5740 | 0.4226 | 0.3131 |
| MCF7 | NVP-TAE684 | 0.37 | uM | LJP6 | 1 | K16 | 72 | hr | 1389 | 1605 | 5147 | 0.3118 | 0.0795 |
| MCF7 | NVP-TAE684 | 0.37 | uM | LJP6 | 2 | K16 | 72 | hr | 1389 | 1685 | 5447 | 0.3093 | 0.1029 |
| MCF7 | NVP-TAE684 | 0.37 | uM | LJP6 | 3 | K16 | 72 | hr | 1389 | 1855 | 5740 | 0.3231 | 0.1518 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 1 | K15 | 72 | hr | 1389 | 1229 | 5147 | 0.2388 | -0.0627 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 2 | K15 | 72 | hr | 1389 | 1131 | 5447 | 0.2076 | -0.0990 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 3 | K15 | 72 | hr | 1389 | 1235 | 5740 | 0.2151 | -0.0558 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 1 | K14 | 72 | hr | 1389 | 1003 | 5147 | 0.1949 | -0.1583 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 2 | K14 | 72 | hr | 1389 | 1068 | 5447 | 0.1960 | -0.1248 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 3 | K14 | 72 | hr | 1389 | 969 | 5740 | 0.1688 | -0.1613 |
| MCF7 | NVP-TAE684 | 10 | uM | LJP6 | 1 | K13 | 72 | hr | 1389 | 927 | 5147 | 0.1801 | -0.1927 |
| MCF7 | NVP-TAE684 | 10 | uM | LJP6 | 2 | K13 | 72 | hr | 1389 | 976 | 5447 | 0.1792 | -0.1639 |
| MCF7 | NVP-TAE684 | 10 | uM | LJP6 | 3 | K13 | 72 | hr | 1389 | 997 | 5740 | 0.1737 | -0.1496 |