LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Luminespib
0.12
uM
LJP5
 2
H17
 72
hr
 1235 1370 4356 0.3145 0.0585
MCF7 Luminespib
0.12
uM
LJP5
 3
H17
 72
hr
 1235 1523 4326 0.3520 0.1227
MCF7 Luminespib
0.37
uM
LJP5
 1
H16
 72
hr
 1235 1367 4119 0.3319 0.0600
MCF7 Luminespib
0.37
uM
LJP5
 2
H16
 72
hr
 1235 1563 4356 0.3588 0.1381
MCF7 Luminespib
0.37
uM
LJP5
 3
H16
 72
hr
 1235 1489 4326 0.3442 0.1088
MCF7 Luminespib
1.11
uM
LJP5
 1
H15
 72
hr
 1235 1435 4119 0.3484 0.0900
MCF7 Luminespib
1.11
uM
LJP5
 2
H15
 72
hr
 1235 1492 4356 0.3425 0.1094
MCF7 Luminespib
1.11
uM
LJP5
 3
H15
 72
hr
 1235 1517 4326 0.3506 0.1203
MCF7 Luminespib
3.33
uM
LJP5
 1
H14
 72
hr
 1235 1347 4119 0.3270 0.0510
MCF7 Luminespib
3.33
uM
LJP5
 2
H14
 72
hr
 1235 1397 4356 0.3207 0.0700
MCF7 Luminespib
3.33
uM
LJP5
 3
H14
 72
hr
 1235 1422 4326 0.3287 0.0809
MCF7 Luminespib
10
uM
LJP5
 1
H13
 72
hr
 1235 1151 4119 0.2794 -0.0399
MCF7 Luminespib
10
uM
LJP5
 2
H13
 72
hr
 1235 1237 4356 0.2840 0.0007
MCF7 Luminespib
10
uM
LJP5
 3
H13
 72
hr
 1235 1311 4326 0.3030 0.0334
MCF7 AZD8330
0.04
uM
LJP5
 1
G24
 72
hr
 1235 2009 4119 0.4877 0.3230
MCF7 AZD8330
0.04
uM
LJP5
 2
G24
 72
hr
 1235 1820 4356 0.4178 0.2375
MCF7 AZD8330
0.04
uM
LJP5
 3
G24
 72
hr
 1235 2138 4326 0.4942 0.3544
MCF7 AZD8330
0.12
uM
LJP5
 1
G23
 72
hr
 1235 1972 4119 0.4787 0.3089
MCF7 AZD8330
0.12
uM
LJP5
 2
G23
 72
hr
 1235 1912 4356 0.4389 0.2715
MCF7 AZD8330
0.12
uM
LJP5
 3
G23
 72
hr
 1235 2076 4326 0.4798 0.3325
MCF7 AZD8330
0.37
uM
LJP5
 1
G22
 72
hr
 1235 2103 4119 0.5105 0.3582
MCF7 AZD8330
0.37
uM
LJP5
 2
G22
 72
hr
 1235 2000 4356 0.4591 0.3034
MCF7 AZD8330
0.37
uM
LJP5
 3
G22
 72
hr
 1235 2166 4326 0.5006 0.3641
MCF7 AZD8330
1.11
uM
LJP5
 1
G21
 72
hr
 1235 2287 4119 0.5552 0.4254
MCF7 AZD8330
1.11
uM
LJP5
 2
G21
 72
hr
 1235 2174 4356 0.4991 0.3646