LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 SNS-032
10
uM
LJP6
 3
H13
 72
hr
 1235 594 4126 0.1440 -0.3435
MCF7 Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 1235 2953 3974 0.7431 0.6769
MCF7 Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 1235 2855 4070 0.7014 0.6274
MCF7 Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 1235 2684 4126 0.6505 0.5620
MCF7 Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 1235 2862 3974 0.7202 0.6461
MCF7 Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 1235 2754 4070 0.6766 0.5937
MCF7 Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 1235 3056 4126 0.7406 0.6830
MCF7 Afatinib
0.37
uM
LJP6
 1
G22
 72
hr
 1235 3471 3974 0.8734 0.8457
MCF7 Afatinib
0.37
uM
LJP6
 2
G22
 72
hr
 1235 3213 4070 0.7894 0.7431
MCF7 Afatinib
0.37
uM
LJP6
 3
G22
 72
hr
 1235 3221 4126 0.7806 0.7346
MCF7 Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 1235 3136 3974 0.7891 0.7378
MCF7 Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 1235 2892 4070 0.7105 0.6396
MCF7 Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 1235 3532 4126 0.8560 0.8290
MCF7 Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 1235 2215 3974 0.5574 0.4139
MCF7 Afatinib
3.33
uM
LJP6
 2
G20
 72
hr
 1235 2392 4070 0.5877 0.4683
MCF7 Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 1235 2244 4126 0.5438 0.4092
MCF7 Afatinib
10
uM
LJP6
 1
G19
 72
hr
 1235 618 3974 0.1555 -0.3370
MCF7 Afatinib
10
uM
LJP6
 2
G19
 72
hr
 1235 738 4070 0.1813 -0.2588
MCF7 Afatinib
10
uM
LJP6
 3
G19
 72
hr
 1235 637 4126 0.1544 -0.3166
MCF7 GSK1904529A
0.04
uM
LJP6
 1
H24
 72
hr
 1235 1966 3974 0.4947 0.3174
MCF7 GSK1904529A
0.04
uM
LJP6
 2
H24
 72
hr
 1235 1909 4070 0.4690 0.2879
MCF7 GSK1904529A
0.04
uM
LJP6
 3
H24
 72
hr
 1235 1984 4126 0.4808 0.3130
MCF7 GSK1904529A
0.12
uM
LJP6
 1
H23
 72
hr
 1235 1715 3974 0.4315 0.2148
MCF7 GSK1904529A
0.12
uM
LJP6
 2
H23
 72
hr
 1235 1859 4070 0.4567 0.2682
MCF7 GSK1904529A
0.12
uM
LJP6
 3
H23
 72
hr
 1235 1781 4126 0.4316 0.2340