LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | CP724714 | 10 | uM | LJP5 | 3 | A07 | 72 | hr | 1235 | 2135 | 4326 | 0.4935 | 0.3533 |
| MCF7 | Alvocidib | 0.04 | uM | LJP6 | 1 | A18 | 72 | hr | 1235 | 1106 | 3974 | 0.2783 | -0.0635 |
| MCF7 | Alvocidib | 0.04 | uM | LJP6 | 2 | A18 | 72 | hr | 1235 | 1183 | 4070 | 0.2906 | -0.0249 |
| MCF7 | Alvocidib | 0.04 | uM | LJP6 | 3 | A18 | 72 | hr | 1235 | 1089 | 4126 | 0.2639 | -0.0699 |
| MCF7 | Alvocidib | 0.12 | uM | LJP6 | 1 | A17 | 72 | hr | 1235 | 722 | 3974 | 0.1817 | -0.2729 |
| MCF7 | Alvocidib | 0.12 | uM | LJP6 | 2 | A17 | 72 | hr | 1235 | 631 | 4070 | 0.1550 | -0.3233 |
| MCF7 | Alvocidib | 0.12 | uM | LJP6 | 3 | A17 | 72 | hr | 1235 | 675 | 4126 | 0.1636 | -0.2935 |
| MCF7 | Alvocidib | 0.37 | uM | LJP6 | 1 | A16 | 72 | hr | 1235 | 677 | 3974 | 0.1704 | -0.3001 |
| MCF7 | Alvocidib | 0.37 | uM | LJP6 | 2 | A16 | 72 | hr | 1235 | 712 | 4070 | 0.1749 | -0.2741 |
| MCF7 | Alvocidib | 0.37 | uM | LJP6 | 3 | A16 | 72 | hr | 1235 | 694 | 4126 | 0.1682 | -0.2821 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 1 | A15 | 72 | hr | 1235 | 609 | 3974 | 0.1532 | -0.3427 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 2 | A15 | 72 | hr | 1235 | 521 | 4070 | 0.1280 | -0.3946 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 3 | A15 | 72 | hr | 1235 | 589 | 4126 | 0.1427 | -0.3467 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 1 | A14 | 72 | hr | 1235 | 563 | 3974 | 0.1417 | -0.3726 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 2 | A14 | 72 | hr | 1235 | 559 | 4070 | 0.1373 | -0.3693 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 3 | A14 | 72 | hr | 1235 | 505 | 4126 | 0.1224 | -0.4020 |
| MCF7 | Alvocidib | 10 | uM | LJP6 | 1 | A13 | 72 | hr | 1235 | 329 | 3974 | 0.0828 | -0.5438 |
| MCF7 | Alvocidib | 10 | uM | LJP6 | 2 | A13 | 72 | hr | 1235 | 578 | 4070 | 0.1420 | -0.3570 |
| MCF7 | Alvocidib | 10 | uM | LJP6 | 3 | A13 | 72 | hr | 1235 | 630 | 4126 | 0.1527 | -0.3209 |
| MCF7 | GW843682X | 0.04 | uM | LJP6 | 1 | B18 | 72 | hr | 1235 | 2869 | 3974 | 0.7219 | 0.6485 |
| MCF7 | GW843682X | 0.04 | uM | LJP6 | 2 | B18 | 72 | hr | 1235 | 3246 | 4070 | 0.7975 | 0.7535 |
| MCF7 | GW843682X | 0.04 | uM | LJP6 | 3 | B18 | 72 | hr | 1235 | 2952 | 4126 | 0.7154 | 0.6498 |
| MCF7 | GW843682X | 0.12 | uM | LJP6 | 1 | B17 | 72 | hr | 1235 | 1318 | 3974 | 0.3318 | 0.0394 |
| MCF7 | GW843682X | 0.12 | uM | LJP6 | 2 | B17 | 72 | hr | 1235 | 1769 | 4070 | 0.4346 | 0.2321 |
| MCF7 | GW843682X | 0.12 | uM | LJP6 | 3 | B17 | 72 | hr | 1235 | 1761 | 4126 | 0.4268 | 0.2260 |