LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PHA-665752 | 3.33 | uM | LJP5 | 3 | F14 | 72 | hr | 1235 | 3901 | 4326 | 0.9017 | 0.8887 |
| MCF7 | PHA-665752 | 10 | uM | LJP5 | 1 | F13 | 72 | hr | 1235 | 3070 | 4119 | 0.7453 | 0.6887 |
| MCF7 | PHA-665752 | 10 | uM | LJP5 | 2 | F13 | 72 | hr | 1235 | 3004 | 4356 | 0.6896 | 0.6302 |
| MCF7 | PHA-665752 | 10 | uM | LJP5 | 3 | F13 | 72 | hr | 1235 | 3014 | 4326 | 0.6967 | 0.6376 |
| MCF7 | PI103 | 0.04 | uM | LJP6 | 1 | I18 | 72 | hr | 1235 | 3488 | 3974 | 0.8777 | 0.8510 |
| MCF7 | PI103 | 0.04 | uM | LJP6 | 2 | I18 | 72 | hr | 1235 | 3429 | 4070 | 0.8424 | 0.8103 |
| MCF7 | PI103 | 0.04 | uM | LJP6 | 3 | I18 | 72 | hr | 1235 | 3492 | 4126 | 0.8463 | 0.8170 |
| MCF7 | PI103 | 0.12 | uM | LJP6 | 1 | I17 | 72 | hr | 1235 | 2463 | 3974 | 0.6198 | 0.5058 |
| MCF7 | PI103 | 0.12 | uM | LJP6 | 2 | I17 | 72 | hr | 1235 | 2514 | 4070 | 0.6176 | 0.5114 |
| MCF7 | PI103 | 0.12 | uM | LJP6 | 3 | I17 | 72 | hr | 1235 | 2438 | 4126 | 0.5908 | 0.4780 |
| MCF7 | PI103 | 0.37 | uM | LJP6 | 1 | I16 | 72 | hr | 1235 | 1617 | 3974 | 0.4069 | 0.1732 |
| MCF7 | PI103 | 0.37 | uM | LJP6 | 2 | I16 | 72 | hr | 1235 | 1452 | 4070 | 0.3567 | 0.0985 |
| MCF7 | PI103 | 0.37 | uM | LJP6 | 3 | I16 | 72 | hr | 1235 | 1552 | 4126 | 0.3761 | 0.1401 |
| MCF7 | PI103 | 1.11 | uM | LJP6 | 1 | I15 | 72 | hr | 1235 | 1314 | 3974 | 0.3306 | 0.0373 |
| MCF7 | PI103 | 1.11 | uM | LJP6 | 2 | I15 | 72 | hr | 1235 | 1182 | 4070 | 0.2904 | -0.0254 |
| MCF7 | PI103 | 1.11 | uM | LJP6 | 3 | I15 | 72 | hr | 1235 | 1173 | 4126 | 0.2843 | -0.0293 |
| MCF7 | PI103 | 3.33 | uM | LJP6 | 1 | I14 | 72 | hr | 1235 | 1086 | 3974 | 0.2733 | -0.0736 |
| MCF7 | PI103 | 3.33 | uM | LJP6 | 2 | I14 | 72 | hr | 1235 | 1215 | 4070 | 0.2985 | -0.0096 |
| MCF7 | PI103 | 3.33 | uM | LJP6 | 3 | I14 | 72 | hr | 1235 | 1143 | 4126 | 0.2770 | -0.0437 |
| MCF7 | PI103 | 10 | uM | LJP6 | 1 | I13 | 72 | hr | 1235 | 1120 | 3974 | 0.2818 | -0.0565 |
| MCF7 | PI103 | 10 | uM | LJP6 | 2 | I13 | 72 | hr | 1235 | 1068 | 4070 | 0.2624 | -0.0812 |
| MCF7 | PI103 | 10 | uM | LJP6 | 3 | I13 | 72 | hr | 1235 | 985 | 4126 | 0.2387 | -0.1221 |
| MCF7 | Dovitinib | 0.04 | uM | LJP5 | 1 | E24 | 72 | hr | 1235 | 3629 | 4119 | 0.8810 | 0.8593 |
| MCF7 | Dovitinib | 0.04 | uM | LJP5 | 2 | E24 | 72 | hr | 1235 | 3764 | 4356 | 0.8640 | 0.8455 |
| MCF7 | Dovitinib | 0.04 | uM | LJP5 | 3 | E24 | 72 | hr | 1235 | 4146 | 4326 | 0.9583 | 0.9534 |