LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Mitoxantrone
10
uM
LJP5
 1
C19
 72
hr
 513 403 10254 0.0393 -0.0545
MCF 10A Mitoxantrone
10
uM
LJP5
 2
C19
 72
hr
 513 379 10349 0.0366 -0.0676
MCF 10A Mitoxantrone
10
uM
LJP5
 3
C19
 72
hr
 513 427 10483 0.0407 -0.0414
MCF 10A Radicicol
0.04
uM
LJP6
 1
K12
 72
hr
 513 6709 10537 0.6367 0.8032
MCF 10A Radicicol
0.04
uM
LJP6
 2
K12
 72
hr
 513 6424 10386 0.6185 0.7903
MCF 10A Radicicol
0.04
uM
LJP6
 3
K12
 72
hr
 513 6031 10494 0.5747 0.7610
MCF 10A Radicicol
0.04
uM
LJP5
 1
K12
 72
hr
 513 6521 10254 0.6359 0.8010
MCF 10A Radicicol
0.04
uM
LJP5
 2
K12
 72
hr
 513 6931 10349 0.6697 0.8233
MCF 10A Radicicol
0.04
uM
LJP5
 3
K12
 72
hr
 513 6411 10483 0.6115 0.7863
MCF 10A Radicicol
0.12
uM
LJP6
 1
K11
 72
hr
 513 2000 10537 0.1898 0.3661
MCF 10A Radicicol
0.12
uM
LJP6
 2
K11
 72
hr
 513 2051 10386 0.1975 0.3761
MCF 10A Radicicol
0.12
uM
LJP6
 3
K11
 72
hr
 513 1503 10494 0.1432 0.2799
MCF 10A Radicicol
0.12
uM
LJP5
 1
K11
 72
hr
 513 2014 10254 0.1964 0.3722
MCF 10A Radicicol
0.12
uM
LJP5
 2
K11
 72
hr
 513 1922 10349 0.1857 0.3561
MCF 10A Radicicol
0.12
uM
LJP5
 3
K11
 72
hr
 513 1315 10483 0.1254 0.2413
MCF 10A Radicicol
0.37
uM
LJP6
 1
K10
 72
hr
 513 935 10537 0.0887 0.1474
MCF 10A Radicicol
0.37
uM
LJP6
 2
K10
 72
hr
 513 861 10386 0.0829 0.1266
MCF 10A Radicicol
0.37
uM
LJP6
 3
K10
 72
hr
 513 727 10494 0.0693 0.0832
MCF 10A Radicicol
0.37
uM
LJP5
 1
K10
 72
hr
 513 896 10254 0.0874 0.1376
MCF 10A Radicicol
0.37
uM
LJP5
 2
K10
 72
hr
 513 816 10349 0.0788 0.1129
MCF 10A Radicicol
0.37
uM
LJP5
 3
K10
 72
hr
 513 670 10483 0.0639 0.0631
MCF 10A Radicicol
1.11
uM
LJP6
 1
K09
 72
hr
 513 795 10537 0.0754 0.1055
MCF 10A Radicicol
1.11
uM
LJP6
 2
K09
 72
hr
 513 889 10386 0.0856 0.1349
MCF 10A Radicicol
1.11
uM
LJP6
 3
K09
 72
hr
 513 542 10494 0.0516 0.0125
MCF 10A Radicicol
1.11
uM
LJP5
 1
K09
 72
hr
 513 813 10254 0.0793 0.1123