LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 PD0325901
1.11
uM
LJP5
 3
C03
 72
hr
 1235 2530 4326 0.5848 0.4865
MCF7 PD0325901
3.33
uM
LJP6
 1
E02
 72
hr
 1235 1569 3974 0.3948 0.1524
MCF7 PD0325901
3.33
uM
LJP6
 2
E02
 72
hr
 1235 1551 4070 0.3811 0.1414
MCF7 PD0325901
3.33
uM
LJP6
 3
E02
 72
hr
 1235 1659 4126 0.4021 0.1847
MCF7 PD0325901
3.33
uM
LJP5
 1
C02
 72
hr
 1235 1689 4119 0.4100 0.1972
MCF7 PD0325901
3.33
uM
LJP5
 2
C02
 72
hr
 1235 1816 4356 0.4169 0.2360
MCF7 PD0325901
3.33
uM
LJP5
 3
C02
 72
hr
 1235 1623 4326 0.3751 0.1629
MCF7 PD0325901
10
uM
LJP6
 1
E01
 72
hr
 1235 1120 3974 0.2818 -0.0565
MCF7 PD0325901
10
uM
LJP6
 2
E01
 72
hr
 1235 1129 4070 0.2774 -0.0510
MCF7 PD0325901
10
uM
LJP6
 3
E01
 72
hr
 1235 1065 4126 0.2581 -0.0818
MCF7 PD0325901
10
uM
LJP5
 1
C01
 72
hr
 1235 1164 4119 0.2826 -0.0337
MCF7 PD0325901
10
uM
LJP5
 2
C01
 72
hr
 1235 1162 4356 0.2667 -0.0331
MCF7 PD0325901
10
uM
LJP5
 3
C01
 72
hr
 1235 1179 4326 0.2725 -0.0255
MCF7 Geldanamycin
0.04
uM
LJP6
 1
O06
 72
hr
 1235 2466 3974 0.6205 0.5069
MCF7 Geldanamycin
0.04
uM
LJP6
 2
O06
 72
hr
 1235 2286 4070 0.5616 0.4301
MCF7 Geldanamycin
0.04
uM
LJP6
 3
O06
 72
hr
 1235 2645 4126 0.6410 0.5489
MCF7 Geldanamycin
0.04
uM
LJP5
 1
O06
 72
hr
 1235 2211 4119 0.5368 0.3980
MCF7 Geldanamycin
0.04
uM
LJP5
 2
O06
 72
hr
 1235 2210 4356 0.5073 0.3770
MCF7 Geldanamycin
0.04
uM
LJP5
 3
O06
 72
hr
 1235 2403 4326 0.5554 0.4448
MCF7 Geldanamycin
0.12
uM
LJP6
 1
O05
 72
hr
 1235 1491 3974 0.3752 0.1180
MCF7 Geldanamycin
0.12
uM
LJP6
 2
O05
 72
hr
 1235 1571 4070 0.3860 0.1499
MCF7 Geldanamycin
0.12
uM
LJP6
 3
O05
 72
hr
 1235 1555 4126 0.3769 0.1414
MCF7 Geldanamycin
0.12
uM
LJP5
 1
O05
 72
hr
 1235 1399 4119 0.3396 0.0742
MCF7 Geldanamycin
0.12
uM
LJP5
 2
O05
 72
hr
 1235 1596 4356 0.3664 0.1513
MCF7 Geldanamycin
0.12
uM
LJP5
 3
O05
 72
hr
 1235 1686 4326 0.3897 0.1877