LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Sigma A6730
0.37
uM
LJP5
 2
B22
 72
hr
 1235 2988 4356 0.6859 0.6255
MCF7 Sigma A6730
0.37
uM
LJP5
 3
B22
 72
hr
 1235 3301 4326 0.7630 0.7221
MCF7 Sigma A6730
1.11
uM
LJP5
 1
B21
 72
hr
 1235 2356 4119 0.5720 0.4500
MCF7 Sigma A6730
1.11
uM
LJP5
 2
B21
 72
hr
 1235 2249 4356 0.5163 0.3903
MCF7 Sigma A6730
1.11
uM
LJP5
 3
B21
 72
hr
 1235 2347 4326 0.5425 0.4261
MCF7 Sigma A6730
3.33
uM
LJP5
 1
B20
 72
hr
 1235 2263 4119 0.5494 0.4168
MCF7 Sigma A6730
3.33
uM
LJP5
 2
B20
 72
hr
 1235 2345 4356 0.5383 0.4226
MCF7 Sigma A6730
3.33
uM
LJP5
 3
B20
 72
hr
 1235 2511 4326 0.5804 0.4803
MCF7 Sigma A6730
10
uM
LJP5
 1
B19
 72
hr
 1235 1201 4119 0.2916 -0.0161
MCF7 Sigma A6730
10
uM
LJP5
 2
B19
 72
hr
 1235 1333 4356 0.3060 0.0427
MCF7 Sigma A6730
10
uM
LJP5
 3
B19
 72
hr
 1235 1099 4326 0.2540 -0.0626
MCF7 WH-4-025
0.04
uM
LJP5
 1
O12
 72
hr
 1235 3987 4119 0.9679 0.9628
MCF7 WH-4-025
0.04
uM
LJP5
 2
O12
 72
hr
 1235 4485 4356 1.0295 1.0323
MCF7 WH-4-025
0.04
uM
LJP5
 3
O12
 72
hr
 1235 4137 4326 0.9562 0.9511
MCF7 WH-4-025
0.12
uM
LJP5
 1
O11
 72
hr
 1235 2640 4119 0.6409 0.5482
MCF7 WH-4-025
0.12
uM
LJP5
 2
O11
 72
hr
 1235 2998 4356 0.6882 0.6284
MCF7 WH-4-025
0.12
uM
LJP5
 3
O11
 72
hr
 1235 2725 4326 0.6299 0.5488
MCF7 WH-4-025
0.37
uM
LJP5
 1
O10
 72
hr
 1235 2018 4119 0.4899 0.3264
MCF7 WH-4-025
0.37
uM
LJP5
 2
O10
 72
hr
 1235 1908 4356 0.4380 0.2701
MCF7 WH-4-025
0.37
uM
LJP5
 3
O10
 72
hr
 1235 1977 4326 0.4570 0.2970
MCF7 WH-4-025
1.11
uM
LJP5
 1
O09
 72
hr
 1235 1014 4119 0.2462 -0.1074
MCF7 WH-4-025
1.11
uM
LJP5
 2
O09
 72
hr
 1235 1285 4356 0.2950 0.0219
MCF7 WH-4-025
1.11
uM
LJP5
 3
O09
 72
hr
 1235 1379 4326 0.3187 0.0627
MCF7 WH-4-025
3.33
uM
LJP5
 1
O08
 72
hr
 1235 1448 4119 0.3515 0.0957
MCF7 WH-4-025
3.33
uM
LJP5
 2
O08
 72
hr
 1235 1305 4356 0.2996 0.0306