LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Dactolisib | 10 | uM | LJP5 | 2 | M13 | 72 | hr | 1476 | 1621 | 3731 | 0.4344 | 0.0722 |
| SK-BR-3 | Dactolisib | 10 | uM | LJP5 | 3 | M13 | 72 | hr | 1476 | 1644 | 3796 | 0.4330 | 0.0820 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 1 | N06 | 72 | hr | 1476 | 3589 | 3788 | 0.9473 | 0.9219 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 2 | N06 | 72 | hr | 1476 | 3254 | 3731 | 0.8721 | 0.8055 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 3 | N06 | 72 | hr | 1476 | 3391 | 3796 | 0.8932 | 0.8408 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 1 | N05 | 72 | hr | 1476 | 3083 | 3788 | 0.8138 | 0.7186 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 2 | N05 | 72 | hr | 1476 | 3238 | 3731 | 0.8678 | 0.7988 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 3 | N05 | 72 | hr | 1476 | 3202 | 3796 | 0.8434 | 0.7649 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 1 | N04 | 72 | hr | 1476 | 2864 | 3788 | 0.7559 | 0.6279 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 2 | N04 | 72 | hr | 1476 | 2745 | 3731 | 0.7357 | 0.5898 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 3 | N04 | 72 | hr | 1476 | 2930 | 3796 | 0.7717 | 0.6536 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 1 | N03 | 72 | hr | 1476 | 2520 | 3788 | 0.6652 | 0.4817 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 2 | N03 | 72 | hr | 1476 | 2604 | 3731 | 0.6979 | 0.5283 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 3 | N03 | 72 | hr | 1476 | 2603 | 3796 | 0.6856 | 0.5160 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 1 | N02 | 72 | hr | 1476 | 2019 | 3788 | 0.5329 | 0.2587 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 2 | N02 | 72 | hr | 1476 | 2136 | 3731 | 0.5725 | 0.3179 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 3 | N02 | 72 | hr | 1476 | 1883 | 3796 | 0.4960 | 0.1953 |
| SK-BR-3 | Alpelisib | 10 | uM | LJP5 | 1 | N01 | 72 | hr | 1476 | 1062 | 3788 | 0.2803 | -0.2154 |
| SK-BR-3 | Alpelisib | 10 | uM | LJP5 | 2 | N01 | 72 | hr | 1476 | 1220 | 3731 | 0.3270 | -0.1331 |
| SK-BR-3 | Alpelisib | 10 | uM | LJP5 | 3 | N01 | 72 | hr | 1476 | 1263 | 3796 | 0.3327 | -0.1084 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 1 | K24 | 72 | hr | 1476 | 1899 | 3788 | 0.5012 | 0.2033 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 2 | K24 | 72 | hr | 1476 | 1718 | 3731 | 0.4604 | 0.1198 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 3 | K24 | 72 | hr | 1476 | 1687 | 3796 | 0.4443 | 0.1027 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 1 | K23 | 72 | hr | 1476 | 1510 | 3788 | 0.3986 | 0.0165 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 2 | K23 | 72 | hr | 1476 | 1475 | 3731 | 0.3953 | -0.0009 |