LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 3 | J02 | 72 | hr | 1476 | 1074 | 3734 | 0.2876 | -0.2117 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 1 | J01 | 72 | hr | 1476 | 700 | 3413 | 0.2051 | -0.4608 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 2 | J01 | 72 | hr | 1476 | 936 | 3783 | 0.2474 | -0.2853 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 3 | J01 | 72 | hr | 1476 | 787 | 3734 | 0.2108 | -0.3752 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 1 | I18 | 72 | hr | 1476 | 3024 | 3788 | 0.7982 | 0.6944 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 2 | I18 | 72 | hr | 1476 | 3073 | 3731 | 0.8236 | 0.7298 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 3 | I18 | 72 | hr | 1476 | 2978 | 3796 | 0.7844 | 0.6734 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 1 | I17 | 72 | hr | 1476 | 2149 | 3788 | 0.5672 | 0.3179 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 2 | I17 | 72 | hr | 1476 | 2203 | 3731 | 0.5904 | 0.3487 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 3 | I17 | 72 | hr | 1476 | 2213 | 3796 | 0.5829 | 0.3457 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 1 | I16 | 72 | hr | 1476 | 1526 | 3788 | 0.4028 | 0.0244 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 2 | I16 | 72 | hr | 1476 | 1430 | 3731 | 0.3833 | -0.0238 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 3 | I16 | 72 | hr | 1476 | 1478 | 3796 | 0.3893 | 0.0006 |
| SK-BR-3 | Pelitinib | 1.11 | uM | LJP5 | 1 | I15 | 72 | hr | 1476 | 1422 | 3788 | 0.3753 | -0.0274 |
| SK-BR-3 | Pelitinib | 1.11 | uM | LJP5 | 2 | I15 | 72 | hr | 1476 | 1625 | 3731 | 0.4355 | 0.0742 |
| SK-BR-3 | Pelitinib | 1.11 | uM | LJP5 | 3 | I15 | 72 | hr | 1476 | 1455 | 3796 | 0.3832 | -0.0108 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 1 | I14 | 72 | hr | 1476 | 1509 | 3788 | 0.3983 | 0.0160 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 2 | I14 | 72 | hr | 1476 | 1659 | 3731 | 0.4446 | 0.0909 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 3 | I14 | 72 | hr | 1476 | 1734 | 3796 | 0.4567 | 0.1251 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 1 | I13 | 72 | hr | 1476 | 1127 | 3788 | 0.2975 | -0.1803 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 2 | I13 | 72 | hr | 1476 | 1057 | 3731 | 0.2833 | -0.2212 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 3 | I13 | 72 | hr | 1476 | 1082 | 3796 | 0.2850 | -0.2041 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 1 | H18 | 72 | hr | 1476 | 1678 | 3788 | 0.4429 | 0.0986 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 2 | H18 | 72 | hr | 1476 | 1604 | 3731 | 0.4299 | 0.0638 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 3 | H18 | 72 | hr | 1476 | 1573 | 3796 | 0.4143 | 0.0475 |