LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PHA-665752 | 3.33 | uM | LJP5 | 2 | F14 | 72 | hr | 1476 | 3876 | 3731 | 1.0388 | 1.0578 |
| SK-BR-3 | PHA-665752 | 3.33 | uM | LJP5 | 3 | F14 | 72 | hr | 1476 | 3681 | 3796 | 0.9695 | 0.9551 |
| SK-BR-3 | PHA-665752 | 10 | uM | LJP5 | 1 | F13 | 72 | hr | 1476 | 841 | 3788 | 0.2220 | -0.3391 |
| SK-BR-3 | PHA-665752 | 10 | uM | LJP5 | 2 | F13 | 72 | hr | 1476 | 881 | 3731 | 0.2361 | -0.3204 |
| SK-BR-3 | PHA-665752 | 10 | uM | LJP5 | 3 | F13 | 72 | hr | 1476 | 1064 | 3796 | 0.2803 | -0.2139 |
| SK-BR-3 | PI103 | 0.04 | uM | LJP6 | 1 | I18 | 72 | hr | 1476 | 3495 | 3413 | 1.0239 | 1.0395 |
| SK-BR-3 | PI103 | 0.04 | uM | LJP6 | 2 | I18 | 72 | hr | 1476 | 3616 | 3783 | 0.9557 | 0.9344 |
| SK-BR-3 | PI103 | 0.04 | uM | LJP6 | 3 | I18 | 72 | hr | 1476 | 3339 | 3734 | 0.8942 | 0.8397 |
| SK-BR-3 | PI103 | 0.12 | uM | LJP6 | 1 | I17 | 72 | hr | 1476 | 2526 | 3413 | 0.7401 | 0.5591 |
| SK-BR-3 | PI103 | 0.12 | uM | LJP6 | 2 | I17 | 72 | hr | 1476 | 2764 | 3783 | 0.7305 | 0.5870 |
| SK-BR-3 | PI103 | 0.12 | uM | LJP6 | 3 | I17 | 72 | hr | 1476 | 2759 | 3734 | 0.7389 | 0.5952 |
| SK-BR-3 | PI103 | 0.37 | uM | LJP6 | 1 | I16 | 72 | hr | 1476 | 1914 | 3413 | 0.5608 | 0.2393 |
| SK-BR-3 | PI103 | 0.37 | uM | LJP6 | 2 | I16 | 72 | hr | 1476 | 1939 | 3783 | 0.5125 | 0.2222 |
| SK-BR-3 | PI103 | 0.37 | uM | LJP6 | 3 | I16 | 72 | hr | 1476 | 2011 | 3734 | 0.5386 | 0.2595 |
| SK-BR-3 | PI103 | 1.11 | uM | LJP6 | 1 | I15 | 72 | hr | 1476 | 1662 | 3413 | 0.4869 | 0.1027 |
| SK-BR-3 | PI103 | 1.11 | uM | LJP6 | 2 | I15 | 72 | hr | 1476 | 1761 | 3783 | 0.4654 | 0.1385 |
| SK-BR-3 | PI103 | 1.11 | uM | LJP6 | 3 | I15 | 72 | hr | 1476 | 1638 | 3734 | 0.4387 | 0.0805 |
| SK-BR-3 | PI103 | 3.33 | uM | LJP6 | 1 | I14 | 72 | hr | 1476 | 1528 | 3413 | 0.4477 | 0.0286 |
| SK-BR-3 | PI103 | 3.33 | uM | LJP6 | 2 | I14 | 72 | hr | 1476 | 1631 | 3783 | 0.4311 | 0.0760 |
| SK-BR-3 | PI103 | 3.33 | uM | LJP6 | 3 | I14 | 72 | hr | 1476 | 1469 | 3734 | 0.3934 | -0.0039 |
| SK-BR-3 | PI103 | 10 | uM | LJP6 | 1 | I13 | 72 | hr | 1476 | 1336 | 3413 | 0.3914 | -0.0795 |
| SK-BR-3 | PI103 | 10 | uM | LJP6 | 2 | I13 | 72 | hr | 1476 | 1426 | 3783 | 0.3769 | -0.0254 |
| SK-BR-3 | PI103 | 10 | uM | LJP6 | 3 | I13 | 72 | hr | 1476 | 1406 | 3734 | 0.3765 | -0.0360 |
| SK-BR-3 | Dovitinib | 0.04 | uM | LJP5 | 1 | E24 | 72 | hr | 1476 | 3162 | 3788 | 0.8346 | 0.7509 |
| SK-BR-3 | Dovitinib | 0.04 | uM | LJP5 | 2 | E24 | 72 | hr | 1476 | 2719 | 3731 | 0.7287 | 0.5785 |