LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
SK-BR-3 BI-2536
0.04
uM
LJP6
 3
D18
 72
hr
 1476 1522 3734 0.4076 0.0228
SK-BR-3 BI-2536
0.12
uM
LJP6
 1
D17
 72
hr
 1476 1425 3413 0.4175 -0.0291
SK-BR-3 BI-2536
0.12
uM
LJP6
 2
D17
 72
hr
 1476 1543 3783 0.4078 0.0329
SK-BR-3 BI-2536
0.12
uM
LJP6
 3
D17
 72
hr
 1476 1335 3734 0.3575 -0.0726
SK-BR-3 BI-2536
0.37
uM
LJP6
 1
D16
 72
hr
 1476 1544 3413 0.4524 0.0375
SK-BR-3 BI-2536
0.37
uM
LJP6
 2
D16
 72
hr
 1476 1731 3783 0.4575 0.1242
SK-BR-3 BI-2536
0.37
uM
LJP6
 3
D16
 72
hr
 1476 1515 3734 0.4057 0.0193
SK-BR-3 BI-2536
1.11
uM
LJP6
 1
D15
 72
hr
 1476 1576 3413 0.4617 0.0553
SK-BR-3 BI-2536
1.11
uM
LJP6
 2
D15
 72
hr
 1476 1539 3783 0.4068 0.0309
SK-BR-3 BI-2536
1.11
uM
LJP6
 3
D15
 72
hr
 1476 1525 3734 0.4084 0.0243
SK-BR-3 BI-2536
3.33
uM
LJP6
 1
D14
 72
hr
 1476 1464 3413 0.4289 -0.0071
SK-BR-3 BI-2536
3.33
uM
LJP6
 2
D14
 72
hr
 1476 1423 3783 0.3761 -0.0269
SK-BR-3 BI-2536
3.33
uM
LJP6
 3
D14
 72
hr
 1476 1391 3734 0.3725 -0.0437
SK-BR-3 BI-2536
10
uM
LJP6
 1
D13
 72
hr
 1476 1464 3413 0.4289 -0.0071
SK-BR-3 BI-2536
10
uM
LJP6
 2
D13
 72
hr
 1476 1504 3783 0.3975 0.0136
SK-BR-3 BI-2536
10
uM
LJP6
 3
D13
 72
hr
 1476 1279 3734 0.3425 -0.1018
SK-BR-3 A443654
0.04
uM
LJP6
 1
I24
 72
hr
 1476 1101 3413 0.3226 -0.2157
SK-BR-3 A443654
0.04
uM
LJP6
 2
I24
 72
hr
 1476 1196 3783 0.3161 -0.1439
SK-BR-3 A443654
0.04
uM
LJP6
 3
I24
 72
hr
 1476 1223 3734 0.3275 -0.1314
SK-BR-3 A443654
0.12
uM
LJP6
 1
I23
 72
hr
 1476 1346 3413 0.3943 -0.0738
SK-BR-3 A443654
0.12
uM
LJP6
 2
I23
 72
hr
 1476 1185 3783 0.3132 -0.1497
SK-BR-3 A443654
0.12
uM
LJP6
 3
I23
 72
hr
 1476 1176 3734 0.3149 -0.1565
SK-BR-3 A443654
0.37
uM
LJP6
 1
I22
 72
hr
 1476 1079 3413 0.3161 -0.2286
SK-BR-3 A443654
0.37
uM
LJP6
 2
I22
 72
hr
 1476 1060 3783 0.2802 -0.2167
SK-BR-3 A443654
0.37
uM
LJP6
 3
I22
 72
hr
 1476 1216 3734 0.3257 -0.1351