LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 1 | A08 | 72 | hr | 1235 | 1388 | 3974 | 0.3493 | 0.0715 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 1 | K03 | 72 | hr | 1235 | 848 | 3974 | 0.2134 | -0.2001 |
| MCF7 | Seliciclib | 0.37 | uM | LJP5 | 1 | J04 | 72 | hr | 1235 | 3699 | 4119 | 0.8980 | 0.8799 |
| MCF7 | AZD8055 | 10 | uM | LJP6 | 1 | A07 | 72 | hr | 1235 | 1197 | 3974 | 0.3012 | -0.0186 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 1235 | 881 | 3974 | 0.2217 | -0.1817 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 1 | J01 | 72 | hr | 1235 | 734 | 4119 | 0.1782 | -0.2589 |
| MCF7 | AZD7762 | 10 | uM | LJP6 | 1 | L01 | 72 | hr | 1235 | 728 | 3974 | 0.1832 | -0.2693 |
| MCF7 | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 1235 | 625 | 3974 | 0.1573 | -0.3325 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 1 | J05 | 72 | hr | 1235 | 4144 | 4119 | 1.0060 | 1.0069 |
| MCF7 | AZD8055 | 0.04 | uM | LJP6 | 1 | A12 | 72 | hr | 1235 | 1330 | 3974 | 0.3347 | 0.0448 |
| MCF7 | AZD7762 | 0.04 | uM | LJP6 | 1 | L06 | 72 | hr | 1235 | 1960 | 3974 | 0.4932 | 0.3150 |
| MCF7 | AT-7519 | 0.04 | uM | LJP6 | 1 | K06 | 72 | hr | 1235 | 3316 | 3974 | 0.8344 | 0.7963 |
| MCF7 | Sorafenib | 10 | uM | LJP6 | 1 | B07 | 72 | hr | 1235 | 1776 | 3974 | 0.4469 | 0.2403 |
| MCF7 | AZD7762 | 0.12 | uM | LJP6 | 1 | L05 | 72 | hr | 1235 | 1766 | 3974 | 0.4444 | 0.2361 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 1 | J03 | 72 | hr | 1235 | 3327 | 4119 | 0.8077 | 0.7686 |
| MCF7 | AZD8055 | 0.37 | uM | LJP6 | 1 | A10 | 72 | hr | 1235 | 1396 | 3974 | 0.3513 | 0.0752 |
| MCF7 | AZD7762 | 0.37 | uM | LJP6 | 1 | L04 | 72 | hr | 1235 | 1658 | 3974 | 0.4172 | 0.1907 |
| MCF7 | AT-7519 | 0.12 | uM | LJP6 | 1 | K05 | 72 | hr | 1235 | 1412 | 3974 | 0.3553 | 0.0825 |
| MCF7 | CP466722 | 3.33 | uM | LJP5 | 1 | I08 | 72 | hr | 1235 | 3958 | 4119 | 0.9609 | 0.9546 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 1 | L03 | 72 | hr | 1235 | 1294 | 3974 | 0.3256 | 0.0279 |
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 1 | J06 | 72 | hr | 1235 | 4760 | 4119 | 1.1556 | 1.1736 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 1 | A09 | 72 | hr | 1235 | 1397 | 3974 | 0.3515 | 0.0757 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 1 | L02 | 72 | hr | 1235 | 1118 | 3974 | 0.2813 | -0.0575 |
| MCF7 | GW843682X | 0.12 | uM | LJP6 | 1 | B17 | 72 | hr | 1235 | 1318 | 3974 | 0.3318 | 0.0394 |
| MCF7 | GW843682X | 0.04 | uM | LJP6 | 1 | B18 | 72 | hr | 1235 | 2869 | 3974 | 0.7219 | 0.6485 |