LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Radicicol
3.33
uM
LJP5
 1
K08
 72
hr
 1235 1592 4119 0.3865 0.1572
MCF7 Radicicol
3.33
uM
LJP5
 2
K08
 72
hr
 1235 1656 4356 0.3801 0.1749
MCF7 Radicicol
3.33
uM
LJP5
 3
K08
 72
hr
 1235 1745 4326 0.4033 0.2105
MCF7 Radicicol
10
uM
LJP6
 1
K07
 72
hr
 1235 990 3974 0.2491 -0.1231
MCF7 Radicicol
10
uM
LJP6
 2
K07
 72
hr
 1235 981 4070 0.2410 -0.1254
MCF7 Radicicol
10
uM
LJP6
 3
K07
 72
hr
 1235 872 4126 0.2113 -0.1814
MCF7 Radicicol
10
uM
LJP5
 1
K07
 72
hr
 1235 1006 4119 0.2442 -0.1115
MCF7 Radicicol
10
uM
LJP5
 2
K07
 72
hr
 1235 972 4356 0.2231 -0.1236
MCF7 Radicicol
10
uM
LJP5
 3
K07
 72
hr
 1235 1018 4326 0.2353 -0.1015
MCF7 Withaferin A
0.04
uM
LJP6
 1
G18
 72
hr
 1235 3506 3974 0.8822 0.8567
MCF7 Withaferin A
0.04
uM
LJP6
 2
G18
 72
hr
 1235 4061 4070 0.9977 0.9973
MCF7 Withaferin A
0.04
uM
LJP6
 3
G18
 72
hr
 1235 4108 4126 0.9956 0.9949
MCF7 Withaferin A
0.04
uM
LJP5
 1
G18
 72
hr
 1235 4895 4119 1.1883 1.2088
MCF7 Withaferin A
0.04
uM
LJP5
 2
G18
 72
hr
 1235 4465 4356 1.0250 1.0273
MCF7 Withaferin A
0.04
uM
LJP5
 3
G18
 72
hr
 1235 4668 4326 1.0789 1.0858
MCF7 Withaferin A
0.12
uM
LJP6
 1
G17
 72
hr
 1235 3014 3974 0.7584 0.6974
MCF7 Withaferin A
0.12
uM
LJP6
 2
G17
 72
hr
 1235 3563 4070 0.8754 0.8511
MCF7 Withaferin A
0.12
uM
LJP6
 3
G17
 72
hr
 1235 3518 4126 0.8526 0.8248
MCF7 Withaferin A
0.12
uM
LJP5
 1
G17
 72
hr
 1235 3879 4119 0.9417 0.9320
MCF7 Withaferin A
0.12
uM
LJP5
 2
G17
 72
hr
 1235 4133 4356 0.9487 0.9430
MCF7 Withaferin A
0.12
uM
LJP5
 3
G17
 72
hr
 1235 3583 4326 0.8282 0.8020
MCF7 Withaferin A
0.37
uM
LJP6
 1
G16
 72
hr
 1235 1769 3974 0.4451 0.2374
MCF7 Withaferin A
0.37
uM
LJP6
 2
G16
 72
hr
 1235 1663 4070 0.4086 0.1886
MCF7 Withaferin A
0.37
uM
LJP6
 3
G16
 72
hr
 1235 1774 4126 0.4299 0.2312
MCF7 Withaferin A
0.37
uM
LJP5
 1
G16
 72
hr
 1235 1830 4119 0.4443 0.2538