LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | OSI-027 | 0.04 | uM | LJP6 | 1 | E12 | 72 | hr | 1476 | 2853 | 3413 | 0.8359 | 0.7243 |
| SK-BR-3 | OSI-027 | 0.04 | uM | LJP6 | 2 | E12 | 72 | hr | 1476 | 3433 | 3783 | 0.9074 | 0.8618 |
| SK-BR-3 | OSI-027 | 0.04 | uM | LJP6 | 3 | E12 | 72 | hr | 1476 | 3536 | 3734 | 0.9470 | 0.9202 |
| SK-BR-3 | OSI-027 | 0.12 | uM | LJP6 | 1 | E11 | 72 | hr | 1476 | 2097 | 3413 | 0.6144 | 0.3366 |
| SK-BR-3 | OSI-027 | 0.12 | uM | LJP6 | 2 | E11 | 72 | hr | 1476 | 2293 | 3783 | 0.6061 | 0.3829 |
| SK-BR-3 | OSI-027 | 0.12 | uM | LJP6 | 3 | E11 | 72 | hr | 1476 | 2409 | 3734 | 0.6451 | 0.4415 |
| SK-BR-3 | OSI-027 | 0.37 | uM | LJP6 | 1 | E10 | 72 | hr | 1476 | 1731 | 3413 | 0.5071 | 0.1405 |
| SK-BR-3 | OSI-027 | 0.37 | uM | LJP6 | 2 | E10 | 72 | hr | 1476 | 1957 | 3783 | 0.5173 | 0.2306 |
| SK-BR-3 | OSI-027 | 0.37 | uM | LJP6 | 3 | E10 | 72 | hr | 1476 | 2040 | 3734 | 0.5463 | 0.2731 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 1 | E09 | 72 | hr | 1476 | 1765 | 3413 | 0.5171 | 0.1590 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 2 | E09 | 72 | hr | 1476 | 1830 | 3783 | 0.4837 | 0.1712 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 3 | E09 | 72 | hr | 1476 | 1951 | 3734 | 0.5225 | 0.2313 |
| SK-BR-3 | OSI-027 | 3.33 | uM | LJP6 | 1 | E08 | 72 | hr | 1476 | 1742 | 3413 | 0.5104 | 0.1465 |
| SK-BR-3 | OSI-027 | 3.33 | uM | LJP6 | 2 | E08 | 72 | hr | 1476 | 1854 | 3783 | 0.4900 | 0.1825 |
| SK-BR-3 | OSI-027 | 3.33 | uM | LJP6 | 3 | E08 | 72 | hr | 1476 | 1801 | 3734 | 0.4823 | 0.1599 |
| SK-BR-3 | OSI-027 | 10 | uM | LJP6 | 1 | E07 | 72 | hr | 1476 | 1795 | 3413 | 0.5259 | 0.1752 |
| SK-BR-3 | OSI-027 | 10 | uM | LJP6 | 2 | E07 | 72 | hr | 1476 | 1569 | 3783 | 0.4147 | 0.0457 |
| SK-BR-3 | OSI-027 | 10 | uM | LJP6 | 3 | E07 | 72 | hr | 1476 | 1586 | 3734 | 0.4247 | 0.0548 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 1 | L12 | 72 | hr | 1476 | 1405 | 3413 | 0.4116 | -0.0404 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 2 | L12 | 72 | hr | 1476 | 1896 | 3783 | 0.5011 | 0.2022 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 3 | L12 | 72 | hr | 1476 | 1967 | 3734 | 0.5268 | 0.2389 |
| SK-BR-3 | WYE-125132 | 0.12 | uM | LJP6 | 1 | L11 | 72 | hr | 1476 | 1393 | 3413 | 0.4081 | -0.0471 |
| SK-BR-3 | WYE-125132 | 0.12 | uM | LJP6 | 2 | L11 | 72 | hr | 1476 | 1741 | 3783 | 0.4602 | 0.1290 |
| SK-BR-3 | WYE-125132 | 0.12 | uM | LJP6 | 3 | L11 | 72 | hr | 1476 | 1556 | 3734 | 0.4167 | 0.0398 |
| SK-BR-3 | WYE-125132 | 0.37 | uM | LJP6 | 1 | L10 | 72 | hr | 1476 | 1095 | 3413 | 0.3208 | -0.2192 |