High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 591 | 329 | | 4059 | 4051 | 149.9 | 44.98 | 152.81 | 103.02 | 95 | 110 | 122 | 134 | 145 | 156 | 170 | 185 | 211 | 0.1824 | 739 | 0.920 | 69.64 | 26.25 | 1 | 0.0493 | 200 | 0.0013 | 36.19 | 6.869 | 0.2026 | 24493.5 | 4340000 | 829000000 | 169000000000 | 0.4381 | 0.2179 | 0.0010 | 0.0000 | 0.0020 | 0.0006 | 0.0237 | 0.0015 | 0.0622 | 0.0050 | 0.1475 | 0.0394 | 0.2153 | 0.0977 | 0.1769 | 0.0924 | 0.1511 | 0.1146 | 0.2203 | 0.6487 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0034 | 0.0008 | 0.0127 | 0.0016 | 0.0491 | 0.0255 | 0.1050 | 0.0516 | 0.0769 | 0.0408 | 0.0978 | 0.0574 | 0.6543 | 0.8222 | 0.0021 | 0.0071 | 0.0032 | 0.0095 | 0.0203 | 0.0309 | 0.0664 | 0.1164 | 0.1756 | 0.2019 | 0.1874 | 0.2233 | 0.1113 | 0.0879 | 0.1520 | 0.1164 | 0.2816 | 0.2067 | 0.0000 | 0.0011 | 0.0070 | 0.0316 | 0.1002 | 0.1522 | 0.0997 | 0.1442 | 0.4641 | 38 | 60 | 81 | 105 | 133 | 164 | 196 | 234 | 296 | 0.0029 | 26.57 | 6.397 | 0.3265 | 33960.4 | 9530000 | 3160000000 | 1200000000000 | 0.5229 | 0.1431 | 0.0171 | 0.0012 | 0.1148 | 0.0116 | 0.2369 | 0.0408 | 0.1685 | 0.0987 | 0.1709 | 0.1749 | 0.1258 | 0.2108 | 0.0733 | 0.1475 | 0.0635 | 0.1511 | 0.0293 | 0.1633 | 0.0000 | 0.0004 | 0.0037 | 0.0011 | 0.0064 | 0.0053 | 0.0320 | 0.0224 | 0.0859 | 0.0765 | 0.1293 | 0.1057 | 0.1028 | 0.0856 | 0.1325 | 0.1118 | 0.5073 | 0.5911 | 0.0037 | 0.0060 | 0.0073 | 0.0140 | 0.0190 | 0.0351 | 0.0467 | 0.0852 | 0.1402 | 0.1543 | 0.1958 | 0.1944 | 0.1242 | 0.1333 | 0.1570 | 0.1353 | 0.3061 | 0.2425 | 0.0017 | 0.0040 | 0.0090 | 0.0384 | 0.0942 | 0.1738 | 0.1196 | 0.1535 | 0.4058 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1135 | 892 | | 1409 | 5293 | 134.3 | 28.05 | 123.64 | 119.19 | 100 | 110 | 119 | 126 | 133 | 139 | 146 | 156 | 174 | 0.1398 | 740 | 0.560 | 124.49 | 24.84 | 1 | 0.2342 | 330 | 0.0027 | 21.21 | 6.129 | 0.2523 | 18811.5 | 2740000 | 416000000 | 65400000000 | 0.4105 | 0.2378 | 0.0011 | 0.0000 | 0.0043 | 0.0000 | 0.0075 | 0.0015 | 0.0247 | 0.0053 | 0.0816 | 0.0356 | 0.1633 | 0.0734 | 0.1429 | 0.0552 | 0.1665 | 0.0953 | 0.4082 | 0.7337 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0120 | 0.0036 | 0.0463 | 0.0252 | 0.0892 | 0.0533 | 0.0729 | 0.0259 | 0.0892 | 0.0497 | 0.6861 | 0.8423 | 0.0043 | 0.0000 | 0.0043 | 0.0746 | 0.0468 | 0.1493 | 0.0766 | 0.2239 | 0.1489 | 0.2388 | 0.1362 | 0.1045 | 0.0894 | 0.0896 | 0.1574 | 0.0746 | 0.3362 | 0.0448 | 0.0029 | 0.0044 | 0.0190 | 0.0452 | 0.0860 | 0.1472 | 0.1297 | 0.1356 | 0.4300 | 24 | 32 | 40 | 53 | 72 | 105 | 153 | 214 | 303 | 0.0149 | 12.61 | 5.403 | 0.4666 | 29488.2 | 9730000 | 3860000000 | 1750000000000 | 0.6071 | 0.1012 | 0.0703 | 0.0066 | 0.2148 | 0.0303 | 0.2890 | 0.0917 | 0.1787 | 0.1523 | 0.1274 | 0.1941 | 0.0837 | 0.2007 | 0.0209 | 0.1302 | 0.0114 | 0.1007 | 0.0038 | 0.0934 | 0.0009 | 0.0015 | 0.0032 | 0.0035 | 0.0111 | 0.0112 | 0.0263 | 0.0235 | 0.0783 | 0.0666 | 0.1188 | 0.1150 | 0.0866 | 0.0850 | 0.1152 | 0.1070 | 0.5597 | 0.5868 | 0.0000 | 0.0036 | 0.0043 | 0.0065 | 0.0201 | 0.0203 | 0.0419 | 0.0443 | 0.0906 | 0.1074 | 0.1404 | 0.1350 | 0.1021 | 0.1103 | 0.1319 | 0.1321 | 0.4687 | 0.4405 | 0.0016 | 0.0037 | 0.0058 | 0.0288 | 0.0885 | 0.1257 | 0.0927 | 0.1225 | 0.5309 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 68 | 826 | | 4128 | 6864 | 146.8 | 44.75 | 144.31 | 126.93 | 100 | 110 | 118 | 127 | 136 | 147 | 160 | 181 | 211 | 0.1005 | 690 | 1.168 | 86.40 | 31.91 | 1 | 0.0540 | 223 | 0.0017 | 33.02 | 6.715 | 0.2229 | 23554.4 | 4140000 | 797000000 | 166000000000 | 0.3837 | 0.2702 | 0.0030 | 0.0000 | 0.0044 | 0.0000 | 0.0178 | 0.0020 | 0.0435 | 0.0054 | 0.1156 | 0.0363 | 0.1789 | 0.0632 | 0.1848 | 0.0697 | 0.1912 | 0.1133 | 0.2609 | 0.7102 | 0.0021 | 0.0000 | 0.0021 | 0.0000 | 0.0065 | 0.0008 | 0.0174 | 0.0018 | 0.0533 | 0.0206 | 0.0793 | 0.0323 | 0.0854 | 0.0354 | 0.1083 | 0.0652 | 0.6456 | 0.8440 | 0.0011 | 0.0066 | 0.0033 | 0.0087 | 0.0299 | 0.0175 | 0.0421 | 0.0611 | 0.0965 | 0.1332 | 0.1275 | 0.1681 | 0.0976 | 0.1201 | 0.1197 | 0.1638 | 0.4823 | 0.3210 | 0.0024 | 0.0042 | 0.0180 | 0.0342 | 0.0792 | 0.1104 | 0.0870 | 0.1309 | 0.5336 | 30 | 44 | 59 | 79 | 101 | 131 | 171 | 232 | 322 | 0.0037 | 48.50 | 6.480 | 0.3040 | 36934.0 | 13300000 | 5910000000 | 3030000000000 | 0.5053 | 0.1536 | 0.0289 | 0.0009 | 0.1252 | 0.0109 | 0.1753 | 0.0639 | 0.1667 | 0.0948 | 0.1830 | 0.1501 | 0.1532 | 0.1791 | 0.0886 | 0.1497 | 0.0559 | 0.1542 | 0.0231 | 0.1964 | 0.0016 | 0.0003 | 0.0026 | 0.0026 | 0.0078 | 0.0059 | 0.0260 | 0.0221 | 0.0809 | 0.0635 | 0.1135 | 0.0910 | 0.0891 | 0.0846 | 0.1135 | 0.1116 | 0.5650 | 0.6183 | 0.0020 | 0.0018 | 0.0025 | 0.0077 | 0.0088 | 0.0196 | 0.0471 | 0.0422 | 0.0972 | 0.1040 | 0.1290 | 0.1337 | 0.1035 | 0.1040 | 0.1295 | 0.1349 | 0.4804 | 0.4522 | 0.0000 | 0.0060 | 0.0116 | 0.0344 | 0.0800 | 0.1244 | 0.1000 | 0.1224 | 0.5214 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1101 | 742 | | 4651 | 3841 | 130.8 | 24.62 | 205.76 | 139.04 | 103 | 111 | 116 | 122 | 128 | 133 | 140 | 148 | 161 | 0.1854 | 712 | 1.111 | 92.85 | 30.41 | 1 | 0.0495 | 230 | 0.0036 | 13.07 | 5.941 | 0.2993 | 17710.9 | 2490000 | 365000000 | 56000000000 | 0.4257 | 0.2249 | 0.0014 | 0.0000 | 0.0040 | 0.0000 | 0.0071 | 0.0000 | 0.0190 | 0.0025 | 0.0451 | 0.0167 | 0.0984 | 0.0362 | 0.1083 | 0.0292 | 0.1549 | 0.0442 | 0.5618 | 0.8712 | 0.0012 | 0.0000 | 0.0029 | 0.0000 | 0.0054 | 0.0000 | 0.0103 | 0.0017 | 0.0254 | 0.0129 | 0.0548 | 0.0241 | 0.0523 | 0.0146 | 0.0807 | 0.0226 | 0.7669 | 0.9241 | 0.0071 | 0.0059 | 0.0196 | 0.0294 | 0.0445 | 0.0471 | 0.0943 | 0.0824 | 0.1423 | 0.1765 | 0.1637 | 0.2176 | 0.1121 | 0.0706 | 0.1174 | 0.1647 | 0.2989 | 0.2059 | 0.0044 | 0.0083 | 0.0151 | 0.0432 | 0.0763 | 0.1122 | 0.1102 | 0.1336 | 0.4968 | 59 | 93 | 118 | 141 | 168 | 200 | 248 | 312 | 412 | 0.0015 | 56.43 | 6.903 | 0.2245 | 61663.9 | 23700000 | 10900000000 | 5660000000000 | 0.4849 | 0.1602 | 0.0169 | 0.0036 | 0.0784 | 0.0118 | 0.1858 | 0.0391 | 0.1701 | 0.0751 | 0.1725 | 0.1438 | 0.1556 | 0.1746 | 0.0941 | 0.1473 | 0.0760 | 0.1444 | 0.0507 | 0.2604 | 0.0020 | 0.0019 | 0.0040 | 0.0035 | 0.0106 | 0.0089 | 0.0323 | 0.0216 | 0.0751 | 0.0589 | 0.1280 | 0.0971 | 0.1154 | 0.0890 | 0.1260 | 0.1125 | 0.5066 | 0.6067 | 0.0017 | 0.0044 | 0.0121 | 0.0077 | 0.0113 | 0.0221 | 0.0459 | 0.0464 | 0.1013 | 0.1380 | 0.1636 | 0.1435 | 0.1022 | 0.1280 | 0.1411 | 0.1523 | 0.4208 | 0.3576 | 0.0020 | 0.0101 | 0.0181 | 0.0322 | 0.0938 | 0.1434 | 0.1139 | 0.1273 | 0.4591 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1111 | 520 | | 5855 | 6285 | 143.7 | 37.71 | 129.84 | 96.11 | 100 | 111 | 121 | 130 | 139 | 148 | 159 | 173 | 193 | 0.1158 | 728 | 1.106 | 84.72 | 30.89 | 1 | 0.0386 | 226 | 0.0018 | 22.88 | 6.593 | 0.2522 | 22082.0 | 3630000 | 639000000 | 120000000000 | 0.4079 | 0.2384 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0053 | 0.0009 | 0.0273 | 0.0032 | 0.0825 | 0.0265 | 0.1384 | 0.0467 | 0.1437 | 0.0495 | 0.1713 | 0.0767 | 0.4291 | 0.7964 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0023 | 0.0007 | 0.0111 | 0.0024 | 0.0330 | 0.0159 | 0.0489 | 0.0238 | 0.0561 | 0.0196 | 0.0820 | 0.0283 | 0.7655 | 0.9092 | 0.0051 | 0.0118 | 0.0093 | 0.0212 | 0.0144 | 0.0259 | 0.0433 | 0.1108 | 0.1155 | 0.1769 | 0.1606 | 0.1792 | 0.1189 | 0.1321 | 0.1589 | 0.1179 | 0.3738 | 0.2241 | 0.0000 | 0.0026 | 0.0098 | 0.0298 | 0.0706 | 0.1009 | 0.1024 | 0.1220 | 0.5618 | 32 | 50 | 66 | 81 | 103 | 128 | 163 | 209 | 265 | 0.0036 | 23.50 | 6.280 | 0.3297 | 26095.3 | 6930000 | 2240000000 | 849000000000 | 0.5029 | 0.1525 | 0.0154 | 0.0026 | 0.0867 | 0.0100 | 0.1762 | 0.0374 | 0.1734 | 0.0756 | 0.1861 | 0.1538 | 0.1463 | 0.2112 | 0.0976 | 0.1556 | 0.0623 | 0.1460 | 0.0560 | 0.2077 | 0.0013 | 0.0013 | 0.0035 | 0.0021 | 0.0061 | 0.0080 | 0.0218 | 0.0157 | 0.0609 | 0.0519 | 0.0984 | 0.0855 | 0.0853 | 0.0703 | 0.1093 | 0.0883 | 0.6133 | 0.6770 | 0.0010 | 0.0013 | 0.0030 | 0.0088 | 0.0075 | 0.0157 | 0.0293 | 0.0452 | 0.0974 | 0.1129 | 0.1546 | 0.1763 | 0.1133 | 0.1129 | 0.1362 | 0.1412 | 0.4578 | 0.3858 | 0.0004 | 0.0036 | 0.0101 | 0.0222 | 0.0677 | 0.1431 | 0.0879 | 0.1278 | 0.5371 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 658 | 779 | | 5169 | 11172 | 137.7 | 32.46 | 113.17 | 91.87 | 100 | 111 | 120 | 127 | 134 | 142 | 150 | 160 | 178 | 0.0719 | 803 | 0.859 | 104.81 | 28.16 | 1 | 0.0530 | 274 | 0.0021 | 21.91 | 6.455 | 0.2447 | 20003.2 | 3080000 | 502000000 | 87100000000 | 0.4380 | 0.2131 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0072 | 0.0000 | 0.0208 | 0.0021 | 0.0760 | 0.0199 | 0.1417 | 0.0475 | 0.1466 | 0.0488 | 0.1981 | 0.0785 | 0.4089 | 0.8031 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0077 | 0.0008 | 0.0363 | 0.0134 | 0.0672 | 0.0294 | 0.0593 | 0.0203 | 0.0997 | 0.0401 | 0.7272 | 0.8959 | 0.0081 | 0.0139 | 0.0185 | 0.0209 | 0.0288 | 0.0453 | 0.0819 | 0.1603 | 0.1453 | 0.1672 | 0.1926 | 0.1812 | 0.1119 | 0.0836 | 0.1407 | 0.1324 | 0.2722 | 0.1951 | 0.0025 | 0.0042 | 0.0148 | 0.0420 | 0.0954 | 0.1238 | 0.1081 | 0.1361 | 0.4731 | 15 | 30 | 49 | 70 | 92 | 118 | 149 | 185 | 238 | 0.0049 | 34.56 | 6.477 | 0.3146 | 21247.0 | 5290000 | 1630000000 | 593000000000 | 0.5230 | 0.1320 | 0.0237 | 0.0013 | 0.1084 | 0.0065 | 0.2323 | 0.0500 | 0.1730 | 0.0940 | 0.1806 | 0.1655 | 0.1412 | 0.2079 | 0.0846 | 0.1542 | 0.0415 | 0.1364 | 0.0146 | 0.1841 | 0.0004 | 0.0003 | 0.0009 | 0.0000 | 0.0057 | 0.0022 | 0.0210 | 0.0114 | 0.0670 | 0.0515 | 0.1169 | 0.0950 | 0.0867 | 0.0772 | 0.1217 | 0.1026 | 0.5799 | 0.6597 | 0.0011 | 0.0007 | 0.0029 | 0.0076 | 0.0111 | 0.0152 | 0.0315 | 0.0444 | 0.0978 | 0.1136 | 0.1574 | 0.1758 | 0.0999 | 0.1242 | 0.1479 | 0.1351 | 0.4505 | 0.3834 | 0.0009 | 0.0021 | 0.0064 | 0.0277 | 0.0813 | 0.1285 | 0.1054 | 0.1321 | 0.5156 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 917 | 765 | | 4787 | 6025 | 134.0 | 29.36 | 199.47 | 144.31 | 101 | 111 | 117 | 124 | 130 | 137 | 145 | 154 | 168 | 0.1200 | 723 | 1.159 | 112.49 | 39.01 | 1 | 0.0570 | 273 | 0.0026 | 20.01 | 6.253 | 0.2547 | 18810.6 | 2780000 | 434000000 | 72000000000 | 0.4427 | 0.2093 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0064 | 0.0013 | 0.0155 | 0.0016 | 0.0709 | 0.0202 | 0.1267 | 0.0377 | 0.1506 | 0.0388 | 0.1815 | 0.0566 | 0.4467 | 0.8438 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0073 | 0.0004 | 0.0405 | 0.0149 | 0.0653 | 0.0246 | 0.0710 | 0.0181 | 0.0965 | 0.0305 | 0.7169 | 0.9114 | 0.0043 | 0.0000 | 0.0157 | 0.0082 | 0.0443 | 0.0286 | 0.0944 | 0.1224 | 0.1688 | 0.1510 | 0.1574 | 0.2041 | 0.0987 | 0.1102 | 0.1273 | 0.1224 | 0.2890 | 0.2531 | 0.0018 | 0.0042 | 0.0125 | 0.0365 | 0.0983 | 0.1347 | 0.1117 | 0.1440 | 0.4564 | 44 | 68 | 100 | 134 | 171 | 211 | 256 | 309 | 392 | 0.0015 | 70.67 | 7.066 | 0.2195 | 60610.6 | 23900000 | 11300000000 | 6160000000000 | 0.5305 | 0.1272 | 0.0202 | 0.0004 | 0.0960 | 0.0047 | 0.2098 | 0.0436 | 0.2030 | 0.0781 | 0.1955 | 0.1872 | 0.1348 | 0.1919 | 0.0851 | 0.1725 | 0.0447 | 0.1552 | 0.0110 | 0.1665 | 0.0006 | 0.0003 | 0.0009 | 0.0005 | 0.0019 | 0.0026 | 0.0206 | 0.0127 | 0.0768 | 0.0560 | 0.1070 | 0.0915 | 0.0989 | 0.0710 | 0.1385 | 0.1099 | 0.5548 | 0.6556 | 0.0015 | 0.0032 | 0.0064 | 0.0097 | 0.0124 | 0.0175 | 0.0500 | 0.0662 | 0.1199 | 0.1364 | 0.1640 | 0.1857 | 0.1189 | 0.1422 | 0.1690 | 0.1513 | 0.3578 | 0.2877 | 0.0008 | 0.0008 | 0.0077 | 0.0291 | 0.0926 | 0.1403 | 0.1170 | 0.1592 | 0.4525 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 122 | 891 | | 5327 | 11696 | 148.0 | 43.59 | 217.70 | 199.22 | 99 | 112 | 123 | 132 | 142 | 151 | 163 | 179 | 203 | 0.0892 | 1043 | 1.215 | 95.34 | 38.64 | 1 | 0.0466 | 248 | 0.0014 | 41.30 | 6.881 | 0.2047 | 23789.2 | 4180000 | 807000000 | 172000000000 | 0.4266 | 0.2289 | 0.0000 | 0.0000 | 0.0056 | 0.0000 | 0.0251 | 0.0013 | 0.0471 | 0.0047 | 0.1157 | 0.0325 | 0.1666 | 0.0629 | 0.1649 | 0.0713 | 0.1997 | 0.1120 | 0.2754 | 0.7151 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0038 | 0.0006 | 0.0121 | 0.0008 | 0.0476 | 0.0188 | 0.0784 | 0.0323 | 0.0758 | 0.0298 | 0.1162 | 0.0531 | 0.6657 | 0.8647 | 0.0082 | 0.0150 | 0.0082 | 0.0107 | 0.0245 | 0.0515 | 0.0927 | 0.1180 | 0.1455 | 0.1888 | 0.1936 | 0.1996 | 0.1264 | 0.1245 | 0.1564 | 0.1352 | 0.2445 | 0.1567 | 0.0017 | 0.0038 | 0.0137 | 0.0384 | 0.0970 | 0.1482 | 0.1179 | 0.1521 | 0.4272 | 20 | 42 | 72 | 110 | 157 | 216 | 283 | 375 | 516 | 0.0025 | 101.46 | 7.379 | 0.2318 | 87079.5 | 45700000 | 28000000000 | 19200000000000 | 0.4833 | 0.1693 | 0.0350 | 0.0024 | 0.1038 | 0.0141 | 0.1931 | 0.0587 | 0.1431 | 0.1069 | 0.1600 | 0.1598 | 0.1213 | 0.1625 | 0.1000 | 0.1305 | 0.0781 | 0.1354 | 0.0656 | 0.2298 | 0.0009 | 0.0005 | 0.0017 | 0.0025 | 0.0061 | 0.0045 | 0.0160 | 0.0176 | 0.0575 | 0.0550 | 0.0955 | 0.0812 | 0.0699 | 0.0655 | 0.1043 | 0.0953 | 0.6482 | 0.6780 | 0.0013 | 0.0012 | 0.0039 | 0.0053 | 0.0078 | 0.0112 | 0.0234 | 0.0287 | 0.0793 | 0.0765 | 0.1139 | 0.1255 | 0.0886 | 0.0921 | 0.1219 | 0.1240 | 0.5599 | 0.5353 | 0.0011 | 0.0013 | 0.0071 | 0.0174 | 0.0656 | 0.1025 | 0.0861 | 0.1177 | 0.6012 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 766 | 509 | | 21316 | 24107 | 152.8 | 47.18 | 163.56 | 211.64 | 92 | 112 | 127 | 140 | 153 | 165 | 177 | 192 | 213 | 0.1036 | 2498 | 0.827 | 32.25 | 8.06 | 7 | 0.0040 | 86 | 0.0005 | 77.74 | 7.966 | 0.1418 | 25560.0 | 4600000 | 879000000 | 178000000000 | 0.4877 | 0.1525 | 0.0009 | 0.0000 | 0.0037 | 0.0002 | 0.0149 | 0.0010 | 0.0428 | 0.0072 | 0.1047 | 0.0330 | 0.1809 | 0.0736 | 0.1588 | 0.0762 | 0.1780 | 0.0986 | 0.3152 | 0.7103 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0020 | 0.0004 | 0.0097 | 0.0036 | 0.0325 | 0.0180 | 0.0642 | 0.0375 | 0.0588 | 0.0332 | 0.0797 | 0.0428 | 0.7519 | 0.8643 | 0.0029 | 0.0050 | 0.0051 | 0.0208 | 0.0156 | 0.0337 | 0.0478 | 0.0972 | 0.1088 | 0.1622 | 0.1603 | 0.2009 | 0.1202 | 0.1275 | 0.1473 | 0.1314 | 0.3919 | 0.2212 | 0.0008 | 0.0017 | 0.0048 | 0.0220 | 0.0553 | 0.0994 | 0.0941 | 0.1118 | 0.6100 | 16 | 20 | 29 | 40 | 58 | 89 | 164 | 305 | 506 | 0.0680 | 12.41 | 4.640 | 0.6115 | 71539.6 | 42800000 | 29400000000 | 22000000000000 | 0.5538 | 0.1336 | 0.0351 | 0.0046 | 0.1280 | 0.0167 | 0.2120 | 0.0578 | 0.1783 | 0.0940 | 0.1652 | 0.1624 | 0.1225 | 0.1970 | 0.0736 | 0.1265 | 0.0427 | 0.1262 | 0.0427 | 0.2147 | 0.0004 | 0.0008 | 0.0014 | 0.0014 | 0.0027 | 0.0031 | 0.0150 | 0.0104 | 0.0386 | 0.0411 | 0.0622 | 0.0561 | 0.0522 | 0.0433 | 0.0703 | 0.0687 | 0.7572 | 0.7752 | 0.0009 | 0.0010 | 0.0030 | 0.0044 | 0.0068 | 0.0054 | 0.0149 | 0.0123 | 0.0452 | 0.0465 | 0.0647 | 0.0707 | 0.0588 | 0.0625 | 0.0807 | 0.0936 | 0.7250 | 0.7037 | 0.0003 | 0.0026 | 0.0046 | 0.0144 | 0.0427 | 0.0684 | 0.0512 | 0.0708 | 0.7451 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 640 | 505 | | 7321 | 15664 | 132.9 | 24.36 | 203.28 | 114.00 | 103 | 113 | 120 | 126 | 131 | 137 | 144 | 152 | 164 | 0.0602 | 943 | 0.886 | 94.20 | 24.52 | 1 | 0.0328 | 240 | 0.0034 | 11.56 | 6.014 | 0.3124 | 18256.5 | 2590000 | 379000000 | 57200000000 | 0.4249 | 0.2269 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0031 | 0.0001 | 0.0107 | 0.0008 | 0.0451 | 0.0126 | 0.0959 | 0.0291 | 0.1106 | 0.0302 | 0.1519 | 0.0455 | 0.5827 | 0.8815 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0013 | 0.0001 | 0.0041 | 0.0006 | 0.0213 | 0.0113 | 0.0421 | 0.0206 | 0.0458 | 0.0151 | 0.0696 | 0.0214 | 0.8160 | 0.9308 | 0.0083 | 0.0311 | 0.0156 | 0.0497 | 0.0353 | 0.0807 | 0.1048 | 0.1491 | 0.1566 | 0.2609 | 0.1940 | 0.1677 | 0.1193 | 0.0621 | 0.1421 | 0.1429 | 0.2241 | 0.0559 | 0.0026 | 0.0048 | 0.0145 | 0.0318 | 0.0705 | 0.1166 | 0.1066 | 0.1362 | 0.5163 | 66 | 100 | 130 | 159 | 188 | 221 | 256 | 298 | 361 | 0.0013 | 36.57 | 7.039 | 0.2500 | 54319.8 | 17300000 | 6280000000 | 2520000000000 | 0.5417 | 0.1374 | 0.0116 | 0.0006 | 0.0610 | 0.0034 | 0.1692 | 0.0206 | 0.1815 | 0.0547 | 0.2027 | 0.1259 | 0.1727 | 0.1917 | 0.1056 | 0.1593 | 0.0625 | 0.1770 | 0.0330 | 0.2666 | 0.0005 | 0.0002 | 0.0016 | 0.0004 | 0.0064 | 0.0030 | 0.0191 | 0.0101 | 0.0584 | 0.0425 | 0.1194 | 0.0871 | 0.0931 | 0.0697 | 0.1203 | 0.1000 | 0.5810 | 0.6870 | 0.0025 | 0.0036 | 0.0078 | 0.0101 | 0.0228 | 0.0258 | 0.0457 | 0.0697 | 0.1071 | 0.1403 | 0.1660 | 0.1930 | 0.1333 | 0.1409 | 0.1465 | 0.1479 | 0.3682 | 0.2686 | 0.0013 | 0.0039 | 0.0104 | 0.0303 | 0.0787 | 0.1477 | 0.1131 | 0.1412 | 0.4735 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 341 | 154 | | 3660 | 2741 | 145.1 | 40.32 | 362.39 | 193.78 | 100 | 113 | 122 | 131 | 139 | 148 | 158 | 173 | 199 | 0.1423 | 390 | 0.690 | 91.44 | 18.79 | 1 | 0.0628 | 230 | 0.0017 | 31.24 | 6.666 | 0.2130 | 22685.8 | 3840000 | 708000000 | 142000000000 | 0.4590 | 0.1971 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0099 | 0.0000 | 0.0292 | 0.0034 | 0.0887 | 0.0281 | 0.1651 | 0.0650 | 0.1547 | 0.0625 | 0.1731 | 0.0940 | 0.3774 | 0.7470 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0018 | 0.0000 | 0.0113 | 0.0020 | 0.0389 | 0.0146 | 0.0752 | 0.0346 | 0.0724 | 0.0242 | 0.0947 | 0.0466 | 0.7043 | 0.8781 | 0.0056 | 0.0031 | 0.0042 | 0.0061 | 0.0225 | 0.0429 | 0.0591 | 0.0982 | 0.1224 | 0.1595 | 0.1758 | 0.2178 | 0.1097 | 0.1012 | 0.1280 | 0.1380 | 0.3727 | 0.2331 | 0.0000 | 0.0056 | 0.0175 | 0.0437 | 0.0936 | 0.1392 | 0.1180 | 0.1311 | 0.4513 | 105 | 176 | 244 | 302 | 359 | 408 | 457 | 521 | 616 | 0.0007 | 113.79 | 7.416 | 0.1244 | 168859.0 | 91300000 | 54900000000 | 35900000000000 | 0.5411 | 0.1415 | 0.0040 | 0.0007 | 0.0464 | 0.0056 | 0.1300 | 0.0190 | 0.1950 | 0.0556 | 0.1963 | 0.0999 | 0.1817 | 0.1955 | 0.1300 | 0.1871 | 0.0756 | 0.1906 | 0.0411 | 0.2461 | 0.0000 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0049 | 0.0305 | 0.0148 | 0.0610 | 0.0473 | 0.1103 | 0.0976 | 0.1139 | 0.0867 | 0.1144 | 0.1114 | 0.5610 | 0.6358 | 0.0032 | 0.0082 | 0.0095 | 0.0148 | 0.0242 | 0.0346 | 0.0621 | 0.0824 | 0.1137 | 0.1466 | 0.1505 | 0.1928 | 0.1232 | 0.1285 | 0.1568 | 0.1450 | 0.3568 | 0.2471 | 0.0007 | 0.0015 | 0.0154 | 0.0308 | 0.0968 | 0.1357 | 0.1086 | 0.1519 | 0.4585 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1142 | 857 | | 7401 | 14616 | 171.0 | 66.26 | 71.29 | 133.72 | 97 | 113 | 126 | 141 | 159 | 177 | 198 | 227 | 267 | 0.0757 | 1106 | 0.455 | 200.25 | 41.00 | 7 | 0.0947 | 701 | 0.0014 | 22.02 | 6.984 | 0.2885 | 33621.9 | 7480000 | 1840000000 | 492000000000 | 0.3427 | 0.2805 | 0.0023 | 0.0008 | 0.0023 | 0.0025 | 0.0164 | 0.0059 | 0.0279 | 0.0086 | 0.0707 | 0.0301 | 0.1250 | 0.0604 | 0.1170 | 0.0539 | 0.1514 | 0.0722 | 0.4868 | 0.7658 | 0.0004 | 0.0005 | 0.0013 | 0.0012 | 0.0054 | 0.0022 | 0.0073 | 0.0043 | 0.0207 | 0.0130 | 0.0326 | 0.0254 | 0.0318 | 0.0221 | 0.0443 | 0.0300 | 0.8561 | 0.9014 | 0.0010 | 0.0000 | 0.0030 | 0.0041 | 0.0094 | 0.0058 | 0.0189 | 0.0386 | 0.0506 | 0.0641 | 0.0839 | 0.1191 | 0.0645 | 0.0994 | 0.0948 | 0.1224 | 0.6738 | 0.5464 | 0.0012 | 0.0025 | 0.0065 | 0.0109 | 0.0349 | 0.0477 | 0.0514 | 0.0767 | 0.7681 | 10 | 12 | 14 | 16 | 20 | 33 | 59 | 100 | 185 | 0.1556 | 7.37 | 3.609 | 0.6941 | 22963.2 | 18300000 | 21700000000 | 29800000000000 | 0.5623 | 0.1121 | 0.0192 | 0.0013 | 0.1028 | 0.0217 | 0.1742 | 0.0579 | 0.2030 | 0.0744 | 0.1838 | 0.1431 | 0.1324 | 0.1783 | 0.0941 | 0.1601 | 0.0662 | 0.1353 | 0.0244 | 0.2279 | 0.0000 | 0.0002 | 0.0020 | 0.0025 | 0.0051 | 0.0046 | 0.0151 | 0.0122 | 0.0523 | 0.0408 | 0.0785 | 0.0615 | 0.0621 | 0.0522 | 0.0923 | 0.0762 | 0.6926 | 0.7500 | 0.0006 | 0.0003 | 0.0012 | 0.0037 | 0.0062 | 0.0075 | 0.0211 | 0.0251 | 0.0699 | 0.0728 | 0.1077 | 0.1162 | 0.0759 | 0.0799 | 0.1107 | 0.1118 | 0.6067 | 0.5827 | 0.0003 | 0.0008 | 0.0031 | 0.0230 | 0.0637 | 0.0872 | 0.0730 | 0.0993 | 0.6497 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1240 | 782 | | 5520 | 5479 | 133.2 | 23.75 | 110.66 | 100.88 | 104 | 113 | 119 | 126 | 132 | 138 | 144 | 152 | 163 | 0.1374 | 753 | 0.999 | 91.29 | 24.70 | 1 | 0.0397 | 219 | 0.0031 | 14.38 | 6.066 | 0.2851 | 18294.8 | 2590000 | 379000000 | 57200000000 | 0.4125 | 0.2388 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0002 | 0.0212 | 0.0007 | 0.0442 | 0.0156 | 0.0934 | 0.0282 | 0.1204 | 0.0252 | 0.1646 | 0.0404 | 0.5507 | 0.8897 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0083 | 0.0002 | 0.0228 | 0.0129 | 0.0452 | 0.0203 | 0.0504 | 0.0132 | 0.0765 | 0.0234 | 0.7949 | 0.9300 | 0.0226 | 0.0169 | 0.0155 | 0.0763 | 0.0523 | 0.1102 | 0.1088 | 0.1102 | 0.1638 | 0.1525 | 0.1723 | 0.2034 | 0.1201 | 0.1356 | 0.1554 | 0.0847 | 0.1893 | 0.1102 | 0.0033 | 0.0089 | 0.0118 | 0.0380 | 0.0687 | 0.1048 | 0.1063 | 0.1384 | 0.5197 | 27 | 36 | 47 | 60 | 75 | 95 | 123 | 168 | 249 | 0.0062 | 29.53 | 5.971 | 0.3642 | 22419.6 | 6640000 | 2430000000 | 1010000000000 | 0.6287 | 0.0903 | 0.0259 | 0.0043 | 0.1147 | 0.0103 | 0.2160 | 0.0511 | 0.1732 | 0.0983 | 0.1395 | 0.1836 | 0.1192 | 0.1825 | 0.0934 | 0.1477 | 0.0742 | 0.1266 | 0.0439 | 0.1955 | 0.0017 | 0.0020 | 0.0034 | 0.0039 | 0.0089 | 0.0098 | 0.0326 | 0.0219 | 0.0852 | 0.0732 | 0.1360 | 0.1023 | 0.1004 | 0.0859 | 0.1513 | 0.1366 | 0.4805 | 0.5644 | 0.0020 | 0.0025 | 0.0095 | 0.0033 | 0.0102 | 0.0172 | 0.0428 | 0.0582 | 0.1292 | 0.1534 | 0.1747 | 0.1838 | 0.1237 | 0.1017 | 0.1475 | 0.1403 | 0.3603 | 0.3396 | 0.0016 | 0.0064 | 0.0155 | 0.0321 | 0.1095 | 0.1474 | 0.1239 | 0.1394 | 0.4241 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 620 | 230 | | 4285 | 3286 | 144.3 | 36.47 | 138.38 | 91.26 | 103 | 114 | 122 | 130 | 138 | 148 | 158 | 173 | 194 | 0.1869 | 614 | 1.042 | 86.49 | 33.29 | 1 | 0.0567 | 243 | 0.0019 | 26.80 | 6.577 | 0.2264 | 22156.9 | 3620000 | 632000000 | 117000000000 | 0.4068 | 0.2461 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0068 | 0.0008 | 0.0409 | 0.0036 | 0.0895 | 0.0250 | 0.1604 | 0.0595 | 0.1805 | 0.0680 | 0.1781 | 0.0883 | 0.3406 | 0.7550 | 0.0003 | 0.0000 | 0.0015 | 0.0000 | 0.0033 | 0.0007 | 0.0152 | 0.0019 | 0.0396 | 0.0150 | 0.0677 | 0.0307 | 0.0793 | 0.0309 | 0.0999 | 0.0421 | 0.6933 | 0.8786 | 0.0023 | 0.0063 | 0.0058 | 0.0284 | 0.0232 | 0.0473 | 0.0719 | 0.1356 | 0.1241 | 0.1703 | 0.1694 | 0.2177 | 0.1230 | 0.1041 | 0.1381 | 0.1104 | 0.3422 | 0.1798 | 0.0011 | 0.0074 | 0.0079 | 0.0370 | 0.0894 | 0.1174 | 0.1259 | 0.1364 | 0.4775 | 49 | 67 | 82 | 100 | 117 | 136 | 159 | 195 | 252 | 0.0034 | 28.02 | 6.143 | 0.3124 | 27476.4 | 7420000 | 2560000000 | 1060000000000 | 0.5807 | 0.0980 | 0.0129 | 0.0006 | 0.0526 | 0.0104 | 0.1671 | 0.0245 | 0.1542 | 0.0736 | 0.1916 | 0.1373 | 0.1729 | 0.1674 | 0.1320 | 0.1582 | 0.0713 | 0.1398 | 0.0456 | 0.2882 | 0.0006 | 0.0000 | 0.0034 | 0.0030 | 0.0130 | 0.0039 | 0.0419 | 0.0226 | 0.1058 | 0.0826 | 0.1533 | 0.1274 | 0.1250 | 0.1044 | 0.1408 | 0.1261 | 0.4163 | 0.5298 | 0.0066 | 0.0075 | 0.0055 | 0.0105 | 0.0362 | 0.0359 | 0.0768 | 0.0734 | 0.1480 | 0.1722 | 0.1612 | 0.1722 | 0.1261 | 0.1257 | 0.1469 | 0.1437 | 0.2928 | 0.2590 | 0.0023 | 0.0046 | 0.0201 | 0.0610 | 0.1251 | 0.1807 | 0.1127 | 0.1490 | 0.3444 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 266 | 832 | | 5052 | 10241 | 147.7 | 42.12 | 164.11 | 146.78 | 101 | 114 | 123 | 132 | 141 | 151 | 163 | 178 | 201 | 0.0842 | 862 | 1.052 | 93.96 | 28.02 | 1 | 0.0449 | 227 | 0.0015 | 34.75 | 6.782 | 0.2136 | 23601.0 | 4100000 | 775000000 | 160000000000 | 0.4351 | 0.2145 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0119 | 0.0004 | 0.0418 | 0.0025 | 0.1162 | 0.0275 | 0.1757 | 0.0555 | 0.1934 | 0.0737 | 0.1916 | 0.1095 | 0.2680 | 0.7309 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0002 | 0.0152 | 0.0008 | 0.0452 | 0.0174 | 0.0714 | 0.0304 | 0.0903 | 0.0289 | 0.1092 | 0.0521 | 0.6665 | 0.8702 | 0.0029 | 0.0073 | 0.0164 | 0.0171 | 0.0299 | 0.0465 | 0.0598 | 0.1345 | 0.1583 | 0.1736 | 0.1631 | 0.1760 | 0.1361 | 0.1100 | 0.1544 | 0.1271 | 0.2790 | 0.2078 | 0.0023 | 0.0041 | 0.0120 | 0.0322 | 0.0989 | 0.1427 | 0.1141 | 0.1542 | 0.4395 | 13 | 30 | 59 | 89 | 123 | 168 | 218 | 280 | 374 | 0.0051 | 65.13 | 6.912 | 0.2905 | 48476.3 | 18800000 | 8740000000 | 4630000000000 | 0.4979 | 0.1489 | 0.0225 | 0.0023 | 0.1359 | 0.0100 | 0.2239 | 0.0492 | 0.1838 | 0.0904 | 0.1746 | 0.1755 | 0.1352 | 0.2178 | 0.0803 | 0.1586 | 0.0331 | 0.1509 | 0.0106 | 0.1453 | 0.0000 | 0.0002 | 0.0014 | 0.0012 | 0.0045 | 0.0043 | 0.0163 | 0.0104 | 0.0593 | 0.0502 | 0.0964 | 0.0849 | 0.0821 | 0.0672 | 0.1055 | 0.0971 | 0.6345 | 0.6846 | 0.0014 | 0.0028 | 0.0029 | 0.0077 | 0.0063 | 0.0120 | 0.0284 | 0.0359 | 0.0831 | 0.0921 | 0.1287 | 0.1354 | 0.1006 | 0.1051 | 0.1284 | 0.1343 | 0.5201 | 0.4747 | 0.0002 | 0.0029 | 0.0059 | 0.0176 | 0.0699 | 0.1148 | 0.0813 | 0.1176 | 0.5899 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 426 | 374 | | 4318 | 14420 | 143.7 | 34.49 | 119.50 | 125.97 | 103 | 114 | 123 | 131 | 140 | 148 | 158 | 170 | 188 | 0.0620 | 894 | 1.020 | 115.11 | 27.29 | 1 | 0.0602 | 260 | 0.0019 | 27.37 | 6.560 | 0.2321 | 21832.7 | 3510000 | 599000000 | 108000000000 | 0.4264 | 0.2220 | 0.0004 | 0.0000 | 0.0035 | 0.0005 | 0.0196 | 0.0012 | 0.0369 | 0.0027 | 0.0914 | 0.0222 | 0.1656 | 0.0530 | 0.1672 | 0.0527 | 0.1770 | 0.0782 | 0.3383 | 0.7894 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0000 | 0.0113 | 0.0014 | 0.0416 | 0.0148 | 0.0794 | 0.0319 | 0.0708 | 0.0195 | 0.1002 | 0.0380 | 0.6908 | 0.8945 | 0.0049 | 0.0114 | 0.0160 | 0.0114 | 0.0294 | 0.0456 | 0.0896 | 0.1787 | 0.1521 | 0.2129 | 0.1816 | 0.2053 | 0.1411 | 0.0913 | 0.1546 | 0.1293 | 0.2307 | 0.1141 | 0.0005 | 0.0031 | 0.0112 | 0.0386 | 0.0910 | 0.1352 | 0.1256 | 0.1546 | 0.4403 | 17 | 24 | 35 | 47 | 65 | 91 | 142 | 211 | 313 | 0.0080 | 38.15 | 6.234 | 0.3884 | 30147.3 | 10600000 | 4400000000 | 2040000000000 | 0.5107 | 0.1394 | 0.0427 | 0.0034 | 0.1280 | 0.0141 | 0.2110 | 0.0584 | 0.1420 | 0.1202 | 0.1528 | 0.1742 | 0.1412 | 0.1803 | 0.1009 | 0.1302 | 0.0559 | 0.1289 | 0.0256 | 0.1903 | 0.0007 | 0.0013 | 0.0025 | 0.0025 | 0.0054 | 0.0058 | 0.0116 | 0.0120 | 0.0497 | 0.0465 | 0.0797 | 0.0690 | 0.0606 | 0.0582 | 0.0869 | 0.0833 | 0.7029 | 0.7214 | 0.0002 | 0.0008 | 0.0009 | 0.0008 | 0.0044 | 0.0074 | 0.0114 | 0.0183 | 0.0634 | 0.0731 | 0.0992 | 0.1123 | 0.0727 | 0.0847 | 0.1113 | 0.1107 | 0.6365 | 0.5920 | 0.0004 | 0.0021 | 0.0035 | 0.0136 | 0.0496 | 0.0910 | 0.0683 | 0.0899 | 0.6816 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 880 | 168 | | 38955 | 26240 | 163.7 | 54.42 | 189.84 | 155.38 | 92 | 114 | 132 | 148 | 164 | 179 | 194 | 210 | 233 | 0.1215 | 3188 | 0.799 | 74.95 | 17.03 | 13 | 0.0043 | 168 | 0.0008 | 32.80 | 7.366 | 0.2060 | 29769.9 | 5880000 | 1240000000 | 280000000000 | 0.5763 | 0.1150 | 0.0010 | 0.0002 | 0.0035 | 0.0005 | 0.0154 | 0.0020 | 0.0472 | 0.0094 | 0.1113 | 0.0378 | 0.1741 | 0.0717 | 0.1653 | 0.0787 | 0.1782 | 0.1069 | 0.3041 | 0.6929 | 0.0003 | 0.0001 | 0.0009 | 0.0002 | 0.0030 | 0.0009 | 0.0108 | 0.0048 | 0.0303 | 0.0203 | 0.0519 | 0.0341 | 0.0512 | 0.0327 | 0.0704 | 0.0446 | 0.7812 | 0.8624 | 0.0018 | 0.0076 | 0.0072 | 0.0135 | 0.0124 | 0.0327 | 0.0413 | 0.0819 | 0.0859 | 0.1325 | 0.1267 | 0.1726 | 0.1108 | 0.1197 | 0.1380 | 0.1307 | 0.4759 | 0.3088 | 0.0012 | 0.0016 | 0.0058 | 0.0209 | 0.0477 | 0.0807 | 0.0801 | 0.1009 | 0.6610 | 30 | 51 | 77 | 110 | 148 | 191 | 245 | 316 | 419 | 0.0043 | 23.31 | 6.446 | 0.3390 | 60178.8 | 24700000 | 11900000000 | 6310000000000 | 0.6103 | 0.0987 | 0.0154 | 0.0035 | 0.0720 | 0.0118 | 0.1491 | 0.0312 | 0.1825 | 0.0787 | 0.1846 | 0.1419 | 0.1799 | 0.1989 | 0.0982 | 0.1547 | 0.0673 | 0.1582 | 0.0509 | 0.2210 | 0.0009 | 0.0008 | 0.0043 | 0.0023 | 0.0067 | 0.0044 | 0.0211 | 0.0165 | 0.0660 | 0.0589 | 0.1135 | 0.1002 | 0.0823 | 0.0792 | 0.1052 | 0.1029 | 0.6000 | 0.6347 | 0.0009 | 0.0028 | 0.0066 | 0.0068 | 0.0095 | 0.0154 | 0.0324 | 0.0388 | 0.0825 | 0.0887 | 0.1348 | 0.1364 | 0.0914 | 0.0993 | 0.1153 | 0.1173 | 0.5266 | 0.4944 | 0.0018 | 0.0040 | 0.0100 | 0.0258 | 0.0759 | 0.1202 | 0.0937 | 0.1112 | 0.5575 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 487 | 388 | | 17803 | 45389 | 157.0 | 50.28 | 154.36 | 177.24 | 92 | 114 | 128 | 142 | 155 | 168 | 183 | 200 | 225 | 0.0425 | 1928 | 1.251 | 24.52 | 7.81 | 5 | 0.0033 | 58 | 0.0011 | 27.12 | 7.140 | 0.2383 | 27189.4 | 5090000 | 1010000000 | 213000000000 | 0.4282 | 0.2106 | 0.0016 | 0.0001 | 0.0027 | 0.0011 | 0.0080 | 0.0022 | 0.0288 | 0.0083 | 0.0923 | 0.0292 | 0.1552 | 0.0530 | 0.1536 | 0.0615 | 0.1813 | 0.0892 | 0.3764 | 0.7554 | 0.0006 | 0.0001 | 0.0008 | 0.0008 | 0.0020 | 0.0012 | 0.0062 | 0.0038 | 0.0238 | 0.0118 | 0.0466 | 0.0193 | 0.0520 | 0.0202 | 0.0673 | 0.0299 | 0.8006 | 0.9130 | 0.0028 | 0.0076 | 0.0051 | 0.0076 | 0.0145 | 0.0286 | 0.0373 | 0.0753 | 0.0821 | 0.1201 | 0.1345 | 0.1711 | 0.1117 | 0.1287 | 0.1381 | 0.1368 | 0.4740 | 0.3241 | 0.0009 | 0.0019 | 0.0057 | 0.0186 | 0.0505 | 0.0897 | 0.0859 | 0.1121 | 0.6346 | 13 | 18 | 26 | 47 | 81 | 128 | 193 | 278 | 407 | 0.0395 | 20.75 | 5.394 | 0.5005 | 55240.7 | 27700000 | 16900000000 | 11900000000000 | 0.4247 | 0.2143 | 0.0378 | 0.0014 | 0.1492 | 0.0110 | 0.2622 | 0.0683 | 0.1893 | 0.1171 | 0.1504 | 0.1913 | 0.1095 | 0.1978 | 0.0586 | 0.1383 | 0.0341 | 0.1296 | 0.0088 | 0.1451 | 0.0003 | 0.0002 | 0.0011 | 0.0008 | 0.0022 | 0.0018 | 0.0130 | 0.0095 | 0.0518 | 0.0406 | 0.0919 | 0.0720 | 0.0661 | 0.0535 | 0.0987 | 0.0822 | 0.6750 | 0.7394 | 0.0006 | 0.0006 | 0.0012 | 0.0024 | 0.0051 | 0.0080 | 0.0184 | 0.0254 | 0.0735 | 0.0834 | 0.1248 | 0.1314 | 0.0862 | 0.0949 | 0.1190 | 0.1284 | 0.5712 | 0.5254 | 0.0004 | 0.0015 | 0.0030 | 0.0169 | 0.0596 | 0.1071 | 0.0813 | 0.1092 | 0.6210 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1257 | 588 | | 6871 | 2051 | 137.3 | 25.65 | 90.04 | 55.86 | 104 | 115 | 123 | 130 | 137 | 144 | 150 | 159 | 170 | 0.3667 | 752 | 0.924 | 92.78 | 24.76 | 1 | 0.0342 | 235 | 0.0024 | 19.20 | 6.305 | 0.2542 | 19504.3 | 2860000 | 432000000 | 67100000000 | 0.4703 | 0.1831 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0058 | 0.0004 | 0.0210 | 0.0004 | 0.0599 | 0.0142 | 0.1283 | 0.0298 | 0.1440 | 0.0322 | 0.2039 | 0.0594 | 0.4358 | 0.8634 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0026 | 0.0004 | 0.0066 | 0.0001 | 0.0250 | 0.0117 | 0.0591 | 0.0222 | 0.0521 | 0.0126 | 0.0901 | 0.0273 | 0.7638 | 0.9256 | 0.0138 | 0.0690 | 0.0324 | 0.0621 | 0.0482 | 0.1724 | 0.1455 | 0.2621 | 0.1888 | 0.1862 | 0.1642 | 0.1517 | 0.1445 | 0.0759 | 0.1259 | 0.0207 | 0.1367 | 0.0000 | 0.0006 | 0.0048 | 0.0097 | 0.0311 | 0.0829 | 0.1268 | 0.1317 | 0.1622 | 0.4503 | 25 | 40 | 54 | 69 | 83 | 97 | 113 | 133 | 160 | 0.0056 | 13.56 | 5.596 | 0.3618 | 11225.5 | 1750000 | 329000000 | 72100000000 | 0.5016 | 0.1610 | 0.0194 | 0.0010 | 0.1282 | 0.0104 | 0.2039 | 0.0604 | 0.1942 | 0.1093 | 0.1515 | 0.1894 | 0.1612 | 0.2362 | 0.0971 | 0.1592 | 0.0291 | 0.1228 | 0.0155 | 0.1113 | 0.0008 | 0.0007 | 0.0067 | 0.0028 | 0.0193 | 0.0104 | 0.0469 | 0.0291 | 0.1182 | 0.0992 | 0.1869 | 0.1881 | 0.1090 | 0.1013 | 0.1534 | 0.1367 | 0.3588 | 0.4316 | 0.0074 | 0.0125 | 0.0251 | 0.0250 | 0.0457 | 0.0813 | 0.0959 | 0.1479 | 0.1504 | 0.1583 | 0.2021 | 0.1813 | 0.1239 | 0.1458 | 0.1431 | 0.1333 | 0.2065 | 0.1146 | 0.0022 | 0.0108 | 0.0390 | 0.0683 | 0.1354 | 0.1788 | 0.1365 | 0.1560 | 0.2730 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1211 | 933 | | 5107 | 8578 | 147.2 | 34.74 | 108.58 | 88.65 | 103 | 115 | 125 | 137 | 146 | 155 | 166 | 176 | 193 | 0.1170 | 1004 | 0.693 | 160.95 | 32.02 | 2 | 0.0770 | 393 | 0.0018 | 21.51 | 6.568 | 0.2519 | 22877.6 | 3740000 | 639000000 | 114000000000 | 0.4445 | 0.2126 | 0.0014 | 0.0000 | 0.0027 | 0.0000 | 0.0102 | 0.0013 | 0.0287 | 0.0064 | 0.0997 | 0.0227 | 0.1387 | 0.0646 | 0.1499 | 0.0612 | 0.1899 | 0.0939 | 0.3788 | 0.7501 | 0.0008 | 0.0000 | 0.0013 | 0.0000 | 0.0046 | 0.0010 | 0.0074 | 0.0038 | 0.0378 | 0.0178 | 0.0555 | 0.0427 | 0.0558 | 0.0299 | 0.0804 | 0.0465 | 0.7565 | 0.8583 | 0.0089 | 0.0213 | 0.0138 | 0.0390 | 0.0296 | 0.0496 | 0.0847 | 0.1277 | 0.1182 | 0.2163 | 0.1665 | 0.1986 | 0.1369 | 0.0957 | 0.1567 | 0.1454 | 0.2847 | 0.1064 | 0.0012 | 0.0048 | 0.0056 | 0.0306 | 0.0692 | 0.1018 | 0.1078 | 0.1301 | 0.5489 | 25 | 38 | 50 | 65 | 83 | 105 | 133 | 168 | 225 | 0.0092 | 9.19 | 5.417 | 0.4488 | 19647.3 | 5050000 | 1670000000 | 658000000000 | 0.5401 | 0.1235 | 0.0262 | 0.0039 | 0.1077 | 0.0159 | 0.2003 | 0.0478 | 0.1830 | 0.0994 | 0.1727 | 0.1452 | 0.1312 | 0.1800 | 0.0932 | 0.1462 | 0.0559 | 0.1481 | 0.0297 | 0.2135 | 0.0012 | 0.0014 | 0.0039 | 0.0039 | 0.0105 | 0.0082 | 0.0233 | 0.0227 | 0.0730 | 0.0560 | 0.1166 | 0.0957 | 0.0997 | 0.0877 | 0.1274 | 0.1094 | 0.5443 | 0.6150 | 0.0027 | 0.0059 | 0.0080 | 0.0113 | 0.0239 | 0.0231 | 0.0448 | 0.0458 | 0.0964 | 0.1241 | 0.1511 | 0.1571 | 0.1120 | 0.1108 | 0.1257 | 0.1349 | 0.4355 | 0.3870 | 0.0018 | 0.0066 | 0.0123 | 0.0361 | 0.0866 | 0.1372 | 0.1032 | 0.1351 | 0.4810 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 445 | 885 | | 6720 | 10576 | 145.0 | 36.97 | 295.37 | 234.47 | 104 | 115 | 123 | 131 | 139 | 148 | 158 | 172 | 194 | 0.1029 | 1088 | 0.626 | 198.72 | 50.01 | 1 | 0.0999 | 671 | 0.0017 | 31.55 | 6.712 | 0.2250 | 22380.3 | 3690000 | 653000000 | 124000000000 | 0.4622 | 0.1938 | 0.0005 | 0.0000 | 0.0030 | 0.0002 | 0.0103 | 0.0013 | 0.0323 | 0.0038 | 0.0867 | 0.0230 | 0.1608 | 0.0551 | 0.1817 | 0.0633 | 0.1822 | 0.0935 | 0.3425 | 0.7598 | 0.0004 | 0.0000 | 0.0019 | 0.0002 | 0.0023 | 0.0009 | 0.0120 | 0.0021 | 0.0362 | 0.0137 | 0.0734 | 0.0334 | 0.0766 | 0.0241 | 0.1038 | 0.0442 | 0.6935 | 0.8815 | 0.0071 | 0.0081 | 0.0063 | 0.0444 | 0.0205 | 0.0282 | 0.0947 | 0.1290 | 0.1539 | 0.1673 | 0.1902 | 0.1714 | 0.1200 | 0.0968 | 0.1350 | 0.1310 | 0.2723 | 0.2238 | 0.0007 | 0.0044 | 0.0119 | 0.0408 | 0.0983 | 0.1353 | 0.1272 | 0.1452 | 0.4362 | 37 | 76 | 126 | 181 | 247 | 316 | 392 | 484 | 624 | 0.0023 | 85.50 | 7.315 | 0.2151 | 142212.0 | 87400000 | 63000000000 | 51000000000000 | 0.5432 | 0.1364 | 0.0279 | 0.0023 | 0.1381 | 0.0113 | 0.2587 | 0.0476 | 0.1904 | 0.1232 | 0.1774 | 0.1886 | 0.1211 | 0.2083 | 0.0551 | 0.1398 | 0.0244 | 0.1359 | 0.0068 | 0.1429 | 0.0004 | 0.0002 | 0.0022 | 0.0026 | 0.0044 | 0.0034 | 0.0196 | 0.0138 | 0.0714 | 0.0585 | 0.1250 | 0.1079 | 0.1052 | 0.0792 | 0.1248 | 0.1135 | 0.5471 | 0.6207 | 0.0022 | 0.0031 | 0.0054 | 0.0083 | 0.0165 | 0.0211 | 0.0326 | 0.0418 | 0.0979 | 0.1017 | 0.1600 | 0.1663 | 0.1128 | 0.1228 | 0.1279 | 0.1459 | 0.4447 | 0.3890 | 0.0009 | 0.0046 | 0.0110 | 0.0265 | 0.0867 | 0.1423 | 0.1125 | 0.1244 | 0.4912 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 824 | 149 | | 3095 | 1375 | 156.7 | 47.45 | 110.15 | 90.82 | 105 | 115 | 124 | 134 | 145 | 160 | 176 | 196 | 227 | 0.3382 | 465 | 1.062 | 83.41 | 29.00 | 1 | 0.0666 | 206 | 0.0014 | 36.35 | 6.808 | 0.1956 | 26798.4 | 4990000 | 1010000000 | 217000000000 | 0.4010 | 0.2369 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0164 | 0.0004 | 0.0622 | 0.0073 | 0.1630 | 0.0383 | 0.2209 | 0.0865 | 0.1773 | 0.0930 | 0.1651 | 0.1290 | 0.1937 | 0.6455 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0066 | 0.0003 | 0.0164 | 0.0033 | 0.0564 | 0.0210 | 0.0986 | 0.0440 | 0.0737 | 0.0367 | 0.1015 | 0.0660 | 0.6458 | 0.8286 | 0.0014 | 0.0026 | 0.0014 | 0.0104 | 0.0096 | 0.0181 | 0.0493 | 0.0907 | 0.1315 | 0.1684 | 0.1685 | 0.1813 | 0.1055 | 0.1192 | 0.1425 | 0.1684 | 0.3904 | 0.2409 | 0.0008 | 0.0000 | 0.0046 | 0.0245 | 0.0772 | 0.1376 | 0.1009 | 0.1223 | 0.5321 | 23 | 34 | 49 | 66 | 79 | 101 | 130 | 181 | 247 | 0.0068 | 27.40 | 5.667 | 0.3730 | 20376.5 | 5090000 | 1510000000 | 502000000000 | 0.4253 | 0.1878 | 0.0226 | 0.0041 | 0.1584 | 0.0225 | 0.2443 | 0.0736 | 0.1493 | 0.0920 | 0.1946 | 0.2086 | 0.1584 | 0.2658 | 0.0588 | 0.1411 | 0.0136 | 0.1022 | 0.0000 | 0.0900 | 0.0000 | 0.0000 | 0.0112 | 0.0048 | 0.0128 | 0.0060 | 0.0400 | 0.0290 | 0.1808 | 0.1351 | 0.2208 | 0.2268 | 0.1120 | 0.1218 | 0.1408 | 0.1375 | 0.2816 | 0.3390 | 0.0050 | 0.0118 | 0.0099 | 0.0147 | 0.0347 | 0.0265 | 0.0743 | 0.0588 | 0.1535 | 0.1971 | 0.2153 | 0.1971 | 0.0990 | 0.1088 | 0.1361 | 0.1412 | 0.2723 | 0.2441 | 0.0039 | 0.0137 | 0.0333 | 0.0412 | 0.1902 | 0.2039 | 0.1000 | 0.1294 | 0.2843 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1178 | 674 | | 5484 | 6809 | 143.9 | 34.02 | 169.15 | 111.62 | 106 | 116 | 124 | 131 | 139 | 147 | 156 | 168 | 188 | 0.1007 | 686 | 1.157 | 112.97 | 41.40 | 1 | 0.0514 | 282 | 0.0021 | 24.63 | 6.515 | 0.2364 | 21871.4 | 3520000 | 604000000 | 111000000000 | 0.4507 | 0.2018 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0058 | 0.0000 | 0.0260 | 0.0006 | 0.0901 | 0.0200 | 0.1435 | 0.0450 | 0.1588 | 0.0427 | 0.1805 | 0.0719 | 0.3939 | 0.8199 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0023 | 0.0000 | 0.0104 | 0.0000 | 0.0398 | 0.0138 | 0.0659 | 0.0247 | 0.0797 | 0.0192 | 0.1000 | 0.0332 | 0.7008 | 0.9092 | 0.0032 | 0.0155 | 0.0181 | 0.0217 | 0.0288 | 0.0342 | 0.0703 | 0.1025 | 0.1384 | 0.1460 | 0.1853 | 0.2267 | 0.1289 | 0.0932 | 0.1310 | 0.1211 | 0.2961 | 0.2391 | 0.0017 | 0.0041 | 0.0120 | 0.0398 | 0.0915 | 0.1441 | 0.1151 | 0.1416 | 0.4501 | 48 | 70 | 90 | 115 | 144 | 176 | 214 | 261 | 331 | 0.0020 | 39.25 | 6.753 | 0.2608 | 41068.8 | 12600000 | 4490000000 | 1800000000000 | 0.5577 | 0.1336 | 0.0189 | 0.0007 | 0.0769 | 0.0043 | 0.1858 | 0.0340 | 0.1829 | 0.0814 | 0.2010 | 0.1571 | 0.1647 | 0.2049 | 0.0885 | 0.1545 | 0.0508 | 0.1578 | 0.0305 | 0.2052 | 0.0008 | 0.0000 | 0.0022 | 0.0007 | 0.0047 | 0.0045 | 0.0230 | 0.0137 | 0.0604 | 0.0531 | 0.1187 | 0.0871 | 0.0787 | 0.0745 | 0.1281 | 0.1004 | 0.5833 | 0.6661 | 0.0022 | 0.0048 | 0.0049 | 0.0048 | 0.0153 | 0.0137 | 0.0431 | 0.0642 | 0.0969 | 0.1220 | 0.1620 | 0.1803 | 0.1184 | 0.1214 | 0.1463 | 0.1642 | 0.4109 | 0.3248 | 0.0017 | 0.0017 | 0.0098 | 0.0258 | 0.0834 | 0.1386 | 0.0988 | 0.1449 | 0.4951 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1075 | 895 | | 4118 | 4934 | 145.3 | 36.15 | 206.60 | 178.21 | 103 | 116 | 125 | 133 | 141 | 149 | 158 | 171 | 192 | 0.1336 | 659 | 0.978 | 89.59 | 26.42 | 1 | 0.0529 | 218 | 0.0019 | 27.36 | 6.598 | 0.2315 | 22405.4 | 3670000 | 641000000 | 119000000000 | 0.4147 | 0.2407 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0093 | 0.0003 | 0.0201 | 0.0030 | 0.0872 | 0.0280 | 0.1515 | 0.0560 | 0.1519 | 0.0633 | 0.1709 | 0.0810 | 0.4076 | 0.7684 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0060 | 0.0007 | 0.0400 | 0.0177 | 0.0771 | 0.0337 | 0.0689 | 0.0327 | 0.0915 | 0.0434 | 0.7140 | 0.8718 | 0.0013 | 0.0068 | 0.0067 | 0.0136 | 0.0324 | 0.0306 | 0.0931 | 0.1054 | 0.1242 | 0.1667 | 0.1768 | 0.1939 | 0.1188 | 0.1224 | 0.1174 | 0.1361 | 0.3293 | 0.2245 | 0.0005 | 0.0037 | 0.0095 | 0.0349 | 0.1138 | 0.1376 | 0.1027 | 0.1466 | 0.4505 | 24 | 53 | 88 | 122 | 160 | 204 | 256 | 333 | 460 | 0.0021 | 74.59 | 7.103 | 0.2341 | 74435.4 | 36000000 | 21000000000 | 13800000000000 | 0.4404 | 0.2138 | 0.0141 | 0.0018 | 0.0633 | 0.0084 | 0.1547 | 0.0349 | 0.1864 | 0.0699 | 0.1934 | 0.1470 | 0.1536 | 0.1946 | 0.1313 | 0.1524 | 0.0610 | 0.1837 | 0.0422 | 0.2072 | 0.0012 | 0.0003 | 0.0033 | 0.0024 | 0.0067 | 0.0058 | 0.0158 | 0.0151 | 0.0596 | 0.0599 | 0.0979 | 0.0767 | 0.0870 | 0.0712 | 0.1083 | 0.1070 | 0.6202 | 0.6615 | 0.0013 | 0.0024 | 0.0071 | 0.0040 | 0.0110 | 0.0176 | 0.0323 | 0.0353 | 0.0788 | 0.0842 | 0.1072 | 0.1259 | 0.0969 | 0.0874 | 0.1111 | 0.1115 | 0.5543 | 0.5317 | 0.0026 | 0.0026 | 0.0067 | 0.0231 | 0.0817 | 0.0966 | 0.0910 | 0.1182 | 0.5776 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 942 | 402 | | 3688 | 2332 | 151.8 | 43.28 | 180.50 | 133.21 | 108 | 117 | 125 | 132 | 140 | 151 | 164 | 182 | 212 | 0.2213 | 516 | 0.931 | 141.17 | 32.02 | 1 | 0.0876 | 323 | 0.0019 | 31.70 | 6.606 | 0.2258 | 24909.7 | 4450000 | 865000000 | 182000000000 | 0.4279 | 0.2128 | 0.0005 | 0.0000 | 0.0025 | 0.0003 | 0.0128 | 0.0000 | 0.0325 | 0.0040 | 0.1019 | 0.0306 | 0.1791 | 0.0553 | 0.1713 | 0.0550 | 0.1688 | 0.0767 | 0.3307 | 0.7782 | 0.0004 | 0.0000 | 0.0015 | 0.0003 | 0.0062 | 0.0000 | 0.0124 | 0.0017 | 0.0433 | 0.0179 | 0.0822 | 0.0261 | 0.0803 | 0.0228 | 0.1047 | 0.0391 | 0.6692 | 0.8922 | 0.0014 | 0.0000 | 0.0083 | 0.0028 | 0.0139 | 0.0165 | 0.0584 | 0.0771 | 0.1210 | 0.1460 | 0.1919 | 0.1983 | 0.1099 | 0.1102 | 0.1140 | 0.1295 | 0.3811 | 0.3196 | 0.0000 | 0.0041 | 0.0129 | 0.0272 | 0.0918 | 0.1162 | 0.0959 | 0.1312 | 0.5207 | 34 | 55 | 81 | 119 | 156 | 194 | 239 | 293 | 359 | 0.0027 | 61.54 | 6.549 | 0.2559 | 50319.2 | 17900000 | 7550000000 | 3670000000000 | 0.4809 | 0.1585 | 0.0235 | 0.0000 | 0.1362 | 0.0214 | 0.1643 | 0.0571 | 0.2136 | 0.1060 | 0.1573 | 0.1655 | 0.1221 | 0.2143 | 0.0798 | 0.1429 | 0.0540 | 0.1179 | 0.0493 | 0.1750 | 0.0000 | 0.0000 | 0.0048 | 0.0027 | 0.0137 | 0.0096 | 0.0299 | 0.0212 | 0.0792 | 0.0745 | 0.1317 | 0.1217 | 0.0800 | 0.0820 | 0.1309 | 0.1046 | 0.5299 | 0.5837 | 0.0037 | 0.0032 | 0.0111 | 0.0064 | 0.0172 | 0.0305 | 0.0382 | 0.0546 | 0.1207 | 0.1396 | 0.1736 | 0.1862 | 0.1219 | 0.1348 | 0.1515 | 0.1605 | 0.3621 | 0.2841 | 0.0020 | 0.0079 | 0.0188 | 0.0327 | 0.0962 | 0.1409 | 0.1111 | 0.1518 | 0.4385 |