High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 951 | 364 | | 5225 | 12570 | 114.6 | 29.24 | 148.81 | 175.19 | 84 | 92 | 98 | 104 | 110 | 116 | 124 | 134 | 151 | 0.0699 | 879 | 0.810 | 72.24 | 18.44 | 1 | 0.0389 | 203 | 0.0030 | 17.44 | 6.162 | 0.2786 | 13983.3 | 1830000 | 261000000 | 40800000000 | 0.4284 | 0.2226 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0091 | 0.0002 | 0.0324 | 0.0035 | 0.0800 | 0.0215 | 0.1378 | 0.0503 | 0.1584 | 0.0530 | 0.2021 | 0.0722 | 0.3790 | 0.7993 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0024 | 0.0000 | 0.0124 | 0.0006 | 0.0398 | 0.0144 | 0.0640 | 0.0290 | 0.0688 | 0.0226 | 0.1076 | 0.0342 | 0.7040 | 0.8992 | 0.0056 | 0.0087 | 0.0111 | 0.0173 | 0.0356 | 0.0376 | 0.0934 | 0.1272 | 0.1446 | 0.1821 | 0.1758 | 0.1792 | 0.1224 | 0.1098 | 0.1313 | 0.1156 | 0.2803 | 0.2225 | 0.0027 | 0.0045 | 0.0145 | 0.0377 | 0.0921 | 0.1403 | 0.1135 | 0.1589 | 0.4358 | 11 | 15 | 26 | 46 | 79 | 124 | 182 | 256 | 391 | 0.0134 | 67.23 | 6.423 | 0.3671 | 52832.2 | 26600000 | 16100000000 | 11000000000000 | 0.5002 | 0.1902 | 0.0463 | 0.0026 | 0.1259 | 0.0198 | 0.2117 | 0.0847 | 0.1593 | 0.1067 | 0.1464 | 0.1418 | 0.1017 | 0.1687 | 0.1017 | 0.1354 | 0.0637 | 0.1313 | 0.0432 | 0.2090 | 0.0002 | 0.0000 | 0.0006 | 0.0005 | 0.0035 | 0.0017 | 0.0186 | 0.0129 | 0.0574 | 0.0525 | 0.0893 | 0.0815 | 0.0763 | 0.0603 | 0.1007 | 0.0887 | 0.6535 | 0.7020 | 0.0005 | 0.0012 | 0.0052 | 0.0030 | 0.0073 | 0.0094 | 0.0250 | 0.0301 | 0.0725 | 0.0779 | 0.1207 | 0.1181 | 0.0816 | 0.0907 | 0.1035 | 0.1026 | 0.5837 | 0.5670 | 0.0000 | 0.0011 | 0.0045 | 0.0194 | 0.0690 | 0.1067 | 0.0853 | 0.1053 | 0.6087 | ||
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 766 | 364 | | 612 | 7645 | 99.6 | 21.09 | 6.51 | 2.18 | 75 | 79 | 85 | 92 | 98 | 105 | 112 | 119 | 128 | 0.0838 | 641 | 1.001 | 51.04 | 15.00 | 4 | 0.2108 | 129 | 0.0248 | 1.73 | 3.950 | 0.5777 | 10364.9 | 1120000 | 126000000 | 14600000000 | 0.4146 | 0.2180 | 0.0027 | 0.0000 | 0.0054 | 0.0017 | 0.0161 | 0.0000 | 0.0591 | 0.0051 | 0.1371 | 0.0460 | 0.1505 | 0.0937 | 0.1505 | 0.0528 | 0.1828 | 0.0971 | 0.2957 | 0.7036 | 0.0020 | 0.0000 | 0.0041 | 0.0017 | 0.0082 | 0.0000 | 0.0184 | 0.0050 | 0.0573 | 0.0416 | 0.0532 | 0.0832 | 0.0798 | 0.0349 | 0.1002 | 0.0666 | 0.6769 | 0.7671 | 0.0171 | 0.0714 | 0.0256 | 0.0000 | 0.0427 | 0.2143 | 0.1026 | 0.0714 | 0.1538 | 0.3571 | 0.1880 | 0.1429 | 0.1453 | 0.0714 | 0.1282 | 0.0714 | 0.1966 | 0.0000 | 0.0034 | 0.0034 | 0.0000 | 0.0340 | 0.1020 | 0.1156 | 0.0918 | 0.1667 | 0.4830 | 4 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0231 | 6.70 | 4.222 | 0.3821 | 47.1 | 374.956 | 3259.55 | 30750.1 | 0.5050 | 0.1580 | 0.0158 | 0.0010 | 0.0559 | 0.0056 | 0.1247 | 0.0165 | 0.1847 | 0.0413 | 0.2309 | 0.0800 | 0.2086 | 0.1523 | 0.1279 | 0.2481 | 0.0454 | 0.2940 | 0.0062 | 0.1611 | 0.0049 | 0.0000 | 0.0237 | 0.0014 | 0.0580 | 0.0062 | 0.1000 | 0.0237 | 0.1395 | 0.0478 | 0.1706 | 0.0950 | 0.1637 | 0.1603 | 0.1675 | 0.2610 | 0.1722 | 0.4047 | 0.1697 | 0.2139 | 0.1713 | 0.1778 | 0.1369 | 0.0909 | 0.1041 | 0.0963 | 0.0881 | 0.1257 | 0.1017 | 0.1176 | 0.1057 | 0.0949 | 0.0857 | 0.0602 | 0.0368 | 0.0227 | 0.0417 | 0.0935 | 0.1240 | 0.1420 | 0.1358 | 0.1317 | 0.1030 | 0.1012 | 0.1272 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 632 | 365 | | 4889 | 13256 | 383.0 | 256.14 | 34.30 | 57.66 | 183 | 197 | 211 | 228 | 257 | 316 | 420 | 590 | 842 | 0.0671 | 890 | 0.504 | 95.59 | 26.87 | 10 | 0.0714 | 349 | 0.0027 | 26.56 | 6.768 | 0.3301 | 212277.0 | 153000000 | 126000000000 | 111000000000000 | 0.4295 | 0.1988 | 0.0014 | 0.0022 | 0.0000 | 0.0011 | 0.0177 | 0.0092 | 0.0477 | 0.0152 | 0.1376 | 0.0656 | 0.2030 | 0.1062 | 0.1444 | 0.0846 | 0.1253 | 0.1084 | 0.3229 | 0.6076 | 0.0000 | 0.0014 | 0.0000 | 0.0007 | 0.0010 | 0.0058 | 0.0030 | 0.0093 | 0.0272 | 0.0319 | 0.0495 | 0.0436 | 0.0302 | 0.0367 | 0.0475 | 0.0480 | 0.8417 | 0.8226 | 0.0000 | 0.0019 | 0.0000 | 0.0000 | 0.0039 | 0.0000 | 0.0070 | 0.0056 | 0.0396 | 0.0318 | 0.0591 | 0.0589 | 0.0311 | 0.0308 | 0.0521 | 0.0421 | 0.8073 | 0.8290 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0325 | 0.0644 | 0.0319 | 0.0576 | 0.8081 | 6 | 7 | 9 | 11 | 13 | 17 | 25 | 40 | 85 | 0.1143 | 7.18 | 3.518 | 0.6992 | 4501.5 | 1130000 | 367000000 | 138000000000 | 0.5010 | 0.1794 | 0.0284 | 0.0102 | 0.0869 | 0.0191 | 0.1446 | 0.0339 | 0.1683 | 0.0750 | 0.1629 | 0.1280 | 0.1299 | 0.1522 | 0.1034 | 0.1314 | 0.1052 | 0.1526 | 0.0704 | 0.2976 | 0.0040 | 0.0039 | 0.0059 | 0.0071 | 0.0075 | 0.0092 | 0.0215 | 0.0184 | 0.0557 | 0.0417 | 0.0796 | 0.0708 | 0.0632 | 0.0565 | 0.0866 | 0.0877 | 0.6759 | 0.7047 | 0.0019 | 0.0022 | 0.0019 | 0.0013 | 0.0095 | 0.0056 | 0.0175 | 0.0233 | 0.0712 | 0.0739 | 0.1086 | 0.1188 | 0.0712 | 0.0774 | 0.1036 | 0.1059 | 0.6145 | 0.5916 | 0.0032 | 0.0064 | 0.0051 | 0.0185 | 0.0543 | 0.1006 | 0.0716 | 0.1016 | 0.6387 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 472 | 365 | | 10152 | 16333 | 306.6 | 57.54 | 224.30 | 196.37 | 237 | 256 | 271 | 285 | 301 | 317 | 336 | 357 | 386 | 0.0678 | 1107 | 0.822 | 136.62 | 44.05 | 1 | 0.0396 | 402 | 0.0006 | 77.66 | 7.651 | 0.1416 | 97320.9 | 31900000 | 10800000000 | 3780000000000 | 0.4559 | 0.2016 | 0.0007 | 0.0000 | 0.0006 | 0.0000 | 0.0038 | 0.0001 | 0.0147 | 0.0006 | 0.0559 | 0.0105 | 0.1218 | 0.0272 | 0.1337 | 0.0260 | 0.1584 | 0.0428 | 0.5103 | 0.8928 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0036 | 0.0001 | 0.0257 | 0.0079 | 0.0578 | 0.0184 | 0.0582 | 0.0109 | 0.0841 | 0.0197 | 0.7693 | 0.9430 | 0.0025 | 0.0159 | 0.0101 | 0.0518 | 0.0297 | 0.0876 | 0.0802 | 0.2072 | 0.1723 | 0.1952 | 0.1799 | 0.1474 | 0.1187 | 0.1036 | 0.1503 | 0.0558 | 0.2563 | 0.1355 | 0.0008 | 0.0025 | 0.0127 | 0.0317 | 0.0909 | 0.1254 | 0.1094 | 0.1379 | 0.4885 | 22 | 46 | 83 | 125 | 173 | 229 | 295 | 376 | 500 | 0.0068 | 69.26 | 6.886 | 0.2834 | 88869.9 | 46400000 | 29000000000 | 20500000000000 | 0.5451 | 0.1262 | 0.0275 | 0.0020 | 0.1405 | 0.0066 | 0.2540 | 0.0553 | 0.1753 | 0.1106 | 0.1531 | 0.1890 | 0.1086 | 0.2034 | 0.0715 | 0.1379 | 0.0376 | 0.1361 | 0.0319 | 0.1591 | 0.0004 | 0.0006 | 0.0004 | 0.0007 | 0.0035 | 0.0023 | 0.0163 | 0.0094 | 0.0680 | 0.0540 | 0.1119 | 0.0867 | 0.0864 | 0.0698 | 0.1192 | 0.1056 | 0.5940 | 0.6708 | 0.0002 | 0.0013 | 0.0020 | 0.0036 | 0.0087 | 0.0107 | 0.0296 | 0.0330 | 0.1018 | 0.1162 | 0.1498 | 0.1759 | 0.1073 | 0.1119 | 0.1433 | 0.1478 | 0.4572 | 0.3996 | 0.0004 | 0.0016 | 0.0045 | 0.0181 | 0.0879 | 0.1310 | 0.0994 | 0.1385 | 0.5186 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 79 | 365 | | 355 | 368 | 98.5 | 34.30 | 743.33 | 441.89 | 53 | 66 | 81 | 90 | 95 | 105 | 117 | 132 | 143 | 0.3995 | 147 | 1.183 | 36.12 | 15.52 | 1 | 0.2817 | 100 | 0.0040 | 43.26 | 5.614 | 0.2000 | 10879.1 | 1310000 | 169000000 | 22900000000 | 0.3710 | 0.2410 | 0.0000 | 0.0000 | 0.0265 | 0.0000 | 0.1060 | 0.0041 | 0.0927 | 0.0122 | 0.1258 | 0.1306 | 0.2053 | 0.1796 | 0.1589 | 0.1469 | 0.1126 | 0.1429 | 0.1722 | 0.3837 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0159 | 0.0067 | 0.0556 | 0.0669 | 0.1032 | 0.0635 | 0.0635 | 0.0535 | 0.1111 | 0.0702 | 0.6468 | 0.7391 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0297 | 0.1111 | 0.0792 | 0.2037 | 0.1386 | 0.2037 | 0.2673 | 0.2037 | 0.1287 | 0.1296 | 0.1287 | 0.1111 | 0.2277 | 0.0370 | 0.0000 | 0.0060 | 0.0060 | 0.0539 | 0.1257 | 0.1796 | 0.0958 | 0.1796 | 0.3533 | 167 | 338 | 432 | 575 | 717 | 837 | 975 | 1120 | 1332 | 0.0029 | 177.01 | 5.867 | 0.1008 | 747281.0 | 884000000 | 1170000000000 | 1.66E+15 | 0.3788 | 0.2356 | 0.0116 | 0.0127 | 0.1744 | 0.0570 | 0.2209 | 0.0633 | 0.2326 | 0.1266 | 0.1512 | 0.2089 | 0.1279 | 0.1835 | 0.0814 | 0.1835 | 0.0000 | 0.0886 | 0.0000 | 0.0759 | 0.0000 | 0.0040 | 0.0230 | 0.0199 | 0.0230 | 0.0199 | 0.0829 | 0.0598 | 0.1429 | 0.1474 | 0.1060 | 0.1235 | 0.1567 | 0.1474 | 0.1751 | 0.1633 | 0.2903 | 0.3147 | 0.0000 | 0.0000 | 0.0076 | 0.0108 | 0.0458 | 0.0323 | 0.0458 | 0.0860 | 0.2061 | 0.2688 | 0.1756 | 0.2151 | 0.1374 | 0.1720 | 0.2443 | 0.1828 | 0.1374 | 0.0323 | 0.0058 | 0.0173 | 0.0405 | 0.0578 | 0.1214 | 0.1445 | 0.1792 | 0.1850 | 0.2486 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 301 | 366 | | 6423 | 26442 | 283.5 | 88.59 | 136.46 | 161.23 | 181 | 203 | 226 | 250 | 273 | 298 | 324 | 354 | 403 | 0.0445 | 1176 | 1.048 | 155.22 | 58.08 | 2 | 0.0629 | 404 | 0.0011 | 32.72 | 7.058 | 0.2184 | 88205.5 | 29900000 | 10900000000 | 4280000000000 | 0.4253 | 0.2195 | 0.0007 | 0.0000 | 0.0034 | 0.0009 | 0.0146 | 0.0032 | 0.0409 | 0.0087 | 0.0940 | 0.0368 | 0.1492 | 0.0716 | 0.1359 | 0.0612 | 0.1683 | 0.0927 | 0.3931 | 0.7248 | 0.0002 | 0.0000 | 0.0009 | 0.0007 | 0.0040 | 0.0017 | 0.0105 | 0.0042 | 0.0296 | 0.0204 | 0.0525 | 0.0362 | 0.0423 | 0.0262 | 0.0710 | 0.0400 | 0.7891 | 0.8707 | 0.0013 | 0.0070 | 0.0064 | 0.0098 | 0.0135 | 0.0209 | 0.0411 | 0.0809 | 0.1046 | 0.1492 | 0.1380 | 0.1618 | 0.1014 | 0.1213 | 0.1444 | 0.1269 | 0.4493 | 0.3222 | 0.0000 | 0.0020 | 0.0040 | 0.0131 | 0.0529 | 0.0827 | 0.0844 | 0.1138 | 0.6471 | 9 | 14 | 24 | 38 | 66 | 107 | 167 | 252 | 373 | 0.0462 | 12.01 | 4.985 | 0.5301 | 44615.1 | 20200000 | 11100000000 | 6860000000000 | 0.4314 | 0.2136 | 0.0461 | 0.0018 | 0.1520 | 0.0172 | 0.2501 | 0.0918 | 0.1590 | 0.1281 | 0.1504 | 0.1891 | 0.1005 | 0.1767 | 0.0606 | 0.1214 | 0.0494 | 0.1181 | 0.0317 | 0.1558 | 0.0002 | 0.0002 | 0.0001 | 0.0004 | 0.0016 | 0.0014 | 0.0128 | 0.0100 | 0.0523 | 0.0437 | 0.0925 | 0.0734 | 0.0653 | 0.0565 | 0.0976 | 0.0819 | 0.6777 | 0.7324 | 0.0001 | 0.0006 | 0.0009 | 0.0013 | 0.0036 | 0.0042 | 0.0155 | 0.0196 | 0.0730 | 0.0822 | 0.1241 | 0.1392 | 0.0858 | 0.0894 | 0.1200 | 0.1337 | 0.5771 | 0.5298 | 0.0001 | 0.0005 | 0.0029 | 0.0149 | 0.0623 | 0.1047 | 0.0750 | 0.1099 | 0.6295 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 994 | 366 | | 5578 | 9502 | 439.0 | 109.23 | 7.27 | 7.81 | 292 | 342 | 380 | 410 | 440 | 471 | 499 | 532 | 577 | 0.0764 | 726 | 0.939 | 87.10 | 28.18 | 1 | 0.0446 | 249 | 0.0007 | 54.37 | 7.463 | 0.1610 | 204683.0 | 101000000 | 51800000000 | 27900000000000 | 0.4190 | 0.2212 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0035 | 0.0004 | 0.0227 | 0.0026 | 0.0796 | 0.0200 | 0.1332 | 0.0381 | 0.1486 | 0.0495 | 0.1674 | 0.0707 | 0.4438 | 0.8187 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0004 | 0.0055 | 0.0021 | 0.0249 | 0.0145 | 0.0386 | 0.0203 | 0.0420 | 0.0202 | 0.0598 | 0.0259 | 0.8277 | 0.9167 | 0.0025 | 0.0150 | 0.0083 | 0.0300 | 0.0108 | 0.0936 | 0.0717 | 0.1685 | 0.1350 | 0.1648 | 0.1983 | 0.1985 | 0.1250 | 0.0749 | 0.1433 | 0.0599 | 0.3050 | 0.1948 | 0.0011 | 0.0014 | 0.0018 | 0.0164 | 0.0513 | 0.0969 | 0.0840 | 0.1033 | 0.6439 | 3 | 4 | 5 | 6 | 6 | 7 | 8 | 8 | 10 | 0.3430 | 0.51 | 1.198 | 0.7294 | 113.9 | 6884.51 | 785459 | 106000000 | 0.5832 | 0.1225 | 0.0192 | 0.0019 | 0.0770 | 0.0156 | 0.1579 | 0.0462 | 0.2263 | 0.1039 | 0.2280 | 0.1979 | 0.1695 | 0.2473 | 0.0885 | 0.2176 | 0.0290 | 0.1308 | 0.0047 | 0.0389 | 0.0061 | 0.0001 | 0.0245 | 0.0052 | 0.0678 | 0.0214 | 0.1121 | 0.0524 | 0.1595 | 0.1246 | 0.1671 | 0.1799 | 0.1649 | 0.2137 | 0.1572 | 0.2103 | 0.1408 | 0.1925 | 0.1745 | 0.1950 | 0.1707 | 0.1376 | 0.1329 | 0.1217 | 0.1097 | 0.1088 | 0.0929 | 0.0945 | 0.0843 | 0.0801 | 0.0659 | 0.0748 | 0.0751 | 0.0786 | 0.0940 | 0.1088 | 0.0231 | 0.0695 | 0.1299 | 0.1560 | 0.1619 | 0.1493 | 0.1157 | 0.0965 | 0.0981 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 306 | 371 | | 4494 | 4270 | 161.8 | 42.70 | 234.69 | 215.83 | 112 | 124 | 135 | 145 | 156 | 167 | 180 | 196 | 218 | 0.1239 | 529 | 1.009 | 96.75 | 25.96 | 1 | 0.0514 | 231 | 0.0014 | 36.68 | 6.820 | 0.2137 | 28010.0 | 5190000 | 1030000000 | 219000000000 | 0.4291 | 0.2251 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0126 | 0.0000 | 0.0423 | 0.0007 | 0.1057 | 0.0278 | 0.1680 | 0.0566 | 0.1590 | 0.0556 | 0.1745 | 0.0831 | 0.3347 | 0.7761 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0047 | 0.0000 | 0.0109 | 0.0005 | 0.0393 | 0.0157 | 0.0730 | 0.0314 | 0.0659 | 0.0243 | 0.0878 | 0.0444 | 0.7163 | 0.8838 | 0.0022 | 0.0030 | 0.0119 | 0.0211 | 0.0249 | 0.0544 | 0.0692 | 0.0967 | 0.1405 | 0.1601 | 0.1665 | 0.1994 | 0.1373 | 0.0967 | 0.1395 | 0.1178 | 0.3081 | 0.2508 | 0.0005 | 0.0040 | 0.0079 | 0.0287 | 0.0773 | 0.1229 | 0.1145 | 0.1378 | 0.5064 | 19 | 34 | 69 | 122 | 179 | 238 | 316 | 406 | 546 | 0.0057 | 104.66 | 6.818 | 0.2641 | 101650.0 | 57600000 | 38800000000 | 29800000000000 | 0.4229 | 0.2444 | 0.0242 | 0.0057 | 0.1288 | 0.0139 | 0.2254 | 0.0632 | 0.1771 | 0.1165 | 0.1659 | 0.1509 | 0.1385 | 0.1985 | 0.0821 | 0.1600 | 0.0403 | 0.1493 | 0.0177 | 0.1419 | 0.0005 | 0.0004 | 0.0005 | 0.0008 | 0.0063 | 0.0025 | 0.0169 | 0.0144 | 0.0743 | 0.0534 | 0.1139 | 0.0974 | 0.0816 | 0.0732 | 0.1071 | 0.1007 | 0.5989 | 0.6572 | 0.0014 | 0.0016 | 0.0034 | 0.0025 | 0.0096 | 0.0140 | 0.0310 | 0.0404 | 0.0855 | 0.0947 | 0.1365 | 0.1417 | 0.0848 | 0.1046 | 0.1192 | 0.1038 | 0.5286 | 0.4967 | 0.0012 | 0.0040 | 0.0058 | 0.0295 | 0.0728 | 0.1248 | 0.0872 | 0.1092 | 0.5656 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 996 | 371 | | 11089 | 20661 | 128.1 | 44.85 | 133.68 | 162.62 | 71 | 85 | 99 | 115 | 127 | 138 | 151 | 166 | 188 | 0.0798 | 1648 | 0.895 | 64.56 | 20.03 | 5 | 0.0157 | 174 | 0.0018 | 12.86 | 6.621 | 0.3191 | 18415.0 | 2900000 | 491000000 | 88000000000 | 0.4803 | 0.1576 | 0.0011 | 0.0006 | 0.0045 | 0.0016 | 0.0117 | 0.0035 | 0.0293 | 0.0084 | 0.0819 | 0.0379 | 0.1359 | 0.0583 | 0.1247 | 0.0644 | 0.1531 | 0.0930 | 0.4578 | 0.7323 | 0.0005 | 0.0003 | 0.0015 | 0.0006 | 0.0021 | 0.0017 | 0.0042 | 0.0037 | 0.0222 | 0.0194 | 0.0351 | 0.0255 | 0.0297 | 0.0272 | 0.0482 | 0.0398 | 0.8566 | 0.8816 | 0.0019 | 0.0046 | 0.0038 | 0.0046 | 0.0118 | 0.0178 | 0.0290 | 0.0462 | 0.0667 | 0.1116 | 0.1062 | 0.1155 | 0.0871 | 0.1063 | 0.1161 | 0.1373 | 0.5774 | 0.4561 | 0.0020 | 0.0040 | 0.0047 | 0.0125 | 0.0360 | 0.0599 | 0.0579 | 0.0894 | 0.7335 | 14 | 19 | 29 | 48 | 73 | 107 | 151 | 215 | 335 | 0.0199 | 22.80 | 5.542 | 0.4729 | 44312.1 | 23700000 | 16900000000 | 14500000000000 | 0.5483 | 0.1240 | 0.0154 | 0.0018 | 0.0718 | 0.0095 | 0.1644 | 0.0294 | 0.1714 | 0.0676 | 0.1731 | 0.1375 | 0.1619 | 0.1889 | 0.0967 | 0.1393 | 0.0751 | 0.1444 | 0.0702 | 0.2815 | 0.0008 | 0.0004 | 0.0017 | 0.0019 | 0.0035 | 0.0031 | 0.0174 | 0.0115 | 0.0505 | 0.0433 | 0.0835 | 0.0717 | 0.0604 | 0.0502 | 0.0852 | 0.0807 | 0.6968 | 0.7370 | 0.0015 | 0.0010 | 0.0051 | 0.0020 | 0.0056 | 0.0073 | 0.0197 | 0.0275 | 0.0672 | 0.0761 | 0.1032 | 0.1073 | 0.0716 | 0.0804 | 0.1082 | 0.1177 | 0.6178 | 0.5806 | 0.0010 | 0.0039 | 0.0055 | 0.0211 | 0.0524 | 0.0978 | 0.0670 | 0.0986 | 0.6527 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1207 | 372 | | 6747 | 8059 | 84.9 | 22.08 | 226.14 | 174.03 | 59 | 67 | 72 | 77 | 82 | 87 | 94 | 102 | 115 | 0.0973 | 784 | 0.311 | 92.65 | 22.47 | 1 | 0.0539 | 364 | 0.0045 | 9.29 | 5.773 | 0.3415 | 7693.6 | 743325 | 76400000 | 8330000000 | 0.4601 | 0.1955 | 0.0008 | 0.0000 | 0.0035 | 0.0002 | 0.0171 | 0.0032 | 0.0403 | 0.0059 | 0.0875 | 0.0285 | 0.1381 | 0.0496 | 0.1482 | 0.0593 | 0.1825 | 0.0963 | 0.3819 | 0.7571 | 0.0002 | 0.0000 | 0.0006 | 0.0002 | 0.0047 | 0.0008 | 0.0110 | 0.0014 | 0.0359 | 0.0141 | 0.0685 | 0.0318 | 0.0726 | 0.0278 | 0.1047 | 0.0507 | 0.7019 | 0.8732 | 0.0043 | 0.0187 | 0.0100 | 0.0280 | 0.0278 | 0.0392 | 0.0563 | 0.1157 | 0.1069 | 0.1530 | 0.1732 | 0.1549 | 0.1354 | 0.1194 | 0.1468 | 0.1269 | 0.3393 | 0.2444 | 0.0013 | 0.0070 | 0.0152 | 0.0394 | 0.0795 | 0.1166 | 0.0994 | 0.1259 | 0.5157 | 30 | 54 | 86 | 130 | 191 | 253 | 322 | 398 | 487 | 0.0018 | 56.22 | 7.234 | 0.2526 | 81419.7 | 35200000 | 16800000000 | 8580000000000 | 0.4421 | 0.1940 | 0.0106 | 0.0013 | 0.0478 | 0.0071 | 0.1354 | 0.0260 | 0.1726 | 0.0586 | 0.2159 | 0.1525 | 0.1850 | 0.2115 | 0.1062 | 0.1406 | 0.0770 | 0.1560 | 0.0496 | 0.2464 | 0.0002 | 0.0000 | 0.0002 | 0.0011 | 0.0022 | 0.0025 | 0.0077 | 0.0053 | 0.0453 | 0.0374 | 0.0716 | 0.0706 | 0.0573 | 0.0443 | 0.0759 | 0.0693 | 0.7395 | 0.7695 | 0.0000 | 0.0000 | 0.0023 | 0.0032 | 0.0043 | 0.0056 | 0.0149 | 0.0269 | 0.0503 | 0.0622 | 0.0897 | 0.1060 | 0.0659 | 0.0779 | 0.1007 | 0.1212 | 0.6719 | 0.5969 | 0.0003 | 0.0017 | 0.0031 | 0.0136 | 0.0454 | 0.0838 | 0.0532 | 0.0830 | 0.7160 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1120 | 374 | | 1013 | 7639 | 932.9 | 280.82 | 18.77 | 68.99 | 520 | 632 | 745 | 866 | 972 | 1068 | 1154 | 1217 | 1274 | 0.0730 | 558 | 0.951 | 63.01 | 16.64 | 2 | 0.1382 | 140 | 0.0016 | 66.58 | 6.568 | 0.1620 | 949022.0 | 1030000000 | 1160000000000 | 1.34E+15 | 0.2997 | 0.3332 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0013 | 0.0141 | 0.0025 | 0.1155 | 0.0401 | 0.2197 | 0.0877 | 0.1380 | 0.0401 | 0.1662 | 0.0677 | 0.3437 | 0.7607 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0000 | 0.0368 | 0.0311 | 0.0637 | 0.0681 | 0.0326 | 0.0219 | 0.0425 | 0.0381 | 0.8201 | 0.8408 | 0.0000 | 0.0000 | 0.0000 | 0.0145 | 0.0000 | 0.0000 | 0.0171 | 0.0580 | 0.0484 | 0.1449 | 0.0883 | 0.1014 | 0.0570 | 0.1014 | 0.0712 | 0.2029 | 0.7179 | 0.3768 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0427 | 0.0816 | 0.0278 | 0.0594 | 0.7885 | 4 | 5 | 6 | 6 | 8 | 8 | 9 | 11 | 13 | 0.1323 | 2.99 | 1.460 | 0.4553 | 5111.7 | 3110000 | 2280000000 | 1870000000000 | 0.4103 | 0.1711 | 0.2687 | 0.1623 | 0.2463 | 0.1455 | 0.2015 | 0.1545 | 0.2612 | 0.1636 | 0.0224 | 0.1325 | 0.0000 | 0.1273 | 0.0000 | 0.0688 | 0.0000 | 0.0416 | 0.0000 | 0.0039 | 0.0357 | 0.1050 | 0.0187 | 0.0915 | 0.0221 | 0.0882 | 0.0306 | 0.0747 | 0.0629 | 0.0571 | 0.0510 | 0.0756 | 0.0952 | 0.0655 | 0.0799 | 0.0756 | 0.6037 | 0.3669 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0066 | 0.0000 | 0.0176 | 0.0143 | 0.0683 | 0.0903 | 0.1101 | 0.1021 | 0.0551 | 0.0570 | 0.0991 | 0.1069 | 0.6410 | 0.6295 | 0.0100 | 0.0060 | 0.0040 | 0.0260 | 0.0680 | 0.0820 | 0.0740 | 0.0900 | 0.6400 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 426 | 374 | | 4318 | 14420 | 143.7 | 34.49 | 119.50 | 125.97 | 103 | 114 | 123 | 131 | 140 | 148 | 158 | 170 | 188 | 0.0620 | 894 | 1.020 | 115.11 | 27.29 | 1 | 0.0602 | 260 | 0.0019 | 27.37 | 6.560 | 0.2321 | 21832.7 | 3510000 | 599000000 | 108000000000 | 0.4264 | 0.2220 | 0.0004 | 0.0000 | 0.0035 | 0.0005 | 0.0196 | 0.0012 | 0.0369 | 0.0027 | 0.0914 | 0.0222 | 0.1656 | 0.0530 | 0.1672 | 0.0527 | 0.1770 | 0.0782 | 0.3383 | 0.7894 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0000 | 0.0113 | 0.0014 | 0.0416 | 0.0148 | 0.0794 | 0.0319 | 0.0708 | 0.0195 | 0.1002 | 0.0380 | 0.6908 | 0.8945 | 0.0049 | 0.0114 | 0.0160 | 0.0114 | 0.0294 | 0.0456 | 0.0896 | 0.1787 | 0.1521 | 0.2129 | 0.1816 | 0.2053 | 0.1411 | 0.0913 | 0.1546 | 0.1293 | 0.2307 | 0.1141 | 0.0005 | 0.0031 | 0.0112 | 0.0386 | 0.0910 | 0.1352 | 0.1256 | 0.1546 | 0.4403 | 17 | 24 | 35 | 47 | 65 | 91 | 142 | 211 | 313 | 0.0080 | 38.15 | 6.234 | 0.3884 | 30147.3 | 10600000 | 4400000000 | 2040000000000 | 0.5107 | 0.1394 | 0.0427 | 0.0034 | 0.1280 | 0.0141 | 0.2110 | 0.0584 | 0.1420 | 0.1202 | 0.1528 | 0.1742 | 0.1412 | 0.1803 | 0.1009 | 0.1302 | 0.0559 | 0.1289 | 0.0256 | 0.1903 | 0.0007 | 0.0013 | 0.0025 | 0.0025 | 0.0054 | 0.0058 | 0.0116 | 0.0120 | 0.0497 | 0.0465 | 0.0797 | 0.0690 | 0.0606 | 0.0582 | 0.0869 | 0.0833 | 0.7029 | 0.7214 | 0.0002 | 0.0008 | 0.0009 | 0.0008 | 0.0044 | 0.0074 | 0.0114 | 0.0183 | 0.0634 | 0.0731 | 0.0992 | 0.1123 | 0.0727 | 0.0847 | 0.1113 | 0.1107 | 0.6365 | 0.5920 | 0.0004 | 0.0021 | 0.0035 | 0.0136 | 0.0496 | 0.0910 | 0.0683 | 0.0899 | 0.6816 | ||
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 599 | 374 | | 6551 | 17041 | 267.6 | 66.19 | 105.49 | 114.89 | 194 | 211 | 226 | 241 | 255 | 271 | 293 | 319 | 363 | 0.0596 | 1016 | 1.053 | 98.33 | 35.17 | 1 | 0.0400 | 262 | 0.0008 | 56.30 | 7.438 | 0.1617 | 75974.1 | 22900000 | 7350000000 | 2490000000000 | 0.4000 | 0.2484 | 0.0008 | 0.0000 | 0.0034 | 0.0003 | 0.0047 | 0.0005 | 0.0238 | 0.0032 | 0.0663 | 0.0219 | 0.1305 | 0.0441 | 0.1370 | 0.0413 | 0.1859 | 0.0657 | 0.4477 | 0.8230 | 0.0004 | 0.0000 | 0.0022 | 0.0000 | 0.0022 | 0.0000 | 0.0124 | 0.0008 | 0.0271 | 0.0139 | 0.0574 | 0.0225 | 0.0594 | 0.0169 | 0.0936 | 0.0300 | 0.7454 | 0.9159 | 0.0048 | 0.0079 | 0.0072 | 0.0099 | 0.0183 | 0.0217 | 0.0462 | 0.0791 | 0.0916 | 0.1462 | 0.1371 | 0.1798 | 0.1139 | 0.1146 | 0.1394 | 0.1462 | 0.4414 | 0.2945 | 0.0018 | 0.0029 | 0.0058 | 0.0282 | 0.0762 | 0.1181 | 0.0986 | 0.1203 | 0.5482 | 12 | 15 | 20 | 33 | 58 | 96 | 143 | 192 | 256 | 0.0374 | 9.37 | 5.007 | 0.5330 | 24326.7 | 7980000 | 3300000000 | 1610000000000 | 0.5431 | 0.1194 | 0.0353 | 0.0003 | 0.2286 | 0.0100 | 0.3382 | 0.1134 | 0.1429 | 0.1621 | 0.1127 | 0.2268 | 0.0793 | 0.2001 | 0.0390 | 0.1222 | 0.0157 | 0.0806 | 0.0082 | 0.0845 | 0.0001 | 0.0000 | 0.0003 | 0.0005 | 0.0014 | 0.0004 | 0.0096 | 0.0081 | 0.0557 | 0.0459 | 0.1000 | 0.0861 | 0.0671 | 0.0552 | 0.0956 | 0.0849 | 0.6703 | 0.7189 | 0.0002 | 0.0006 | 0.0016 | 0.0026 | 0.0019 | 0.0060 | 0.0157 | 0.0227 | 0.0714 | 0.0843 | 0.1314 | 0.1389 | 0.0812 | 0.0897 | 0.1127 | 0.1180 | 0.5839 | 0.5372 | 0.0002 | 0.0008 | 0.0031 | 0.0103 | 0.0642 | 0.1150 | 0.0771 | 0.1071 | 0.6223 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 986 | 375 | | 3412 | 6862 | 481.9 | 117.20 | 93.02 | 146.48 | 305 | 387 | 443 | 490 | 520 | 538 | 554 | 572 | 596 | 0.0851 | 584 | 0.932 | 72.01 | 24.21 | 1 | 0.0592 | 202 | 0.0011 | 37.12 | 7.131 | 0.2177 | 245995.0 | 130000000 | 70600000000 | 39000000000000 | 0.3975 | 0.2313 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0023 | 0.0000 | 0.0153 | 0.0006 | 0.0384 | 0.0161 | 0.0685 | 0.0274 | 0.0782 | 0.0187 | 0.1319 | 0.0332 | 0.6645 | 0.9040 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0179 | 0.0160 | 0.0285 | 0.0249 | 0.0223 | 0.0150 | 0.0347 | 0.0278 | 0.8936 | 0.9159 | 0.0209 | 0.0435 | 0.0104 | 0.0000 | 0.0330 | 0.0000 | 0.0557 | 0.0435 | 0.0783 | 0.3478 | 0.0870 | 0.1739 | 0.0991 | 0.0000 | 0.1113 | 0.3043 | 0.5043 | 0.0870 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0247 | 0.0451 | 0.0400 | 0.0679 | 0.8162 | 10 | 13 | 16 | 21 | 27 | 40 | 68 | 138 | 287 | 0.0426 | 28.93 | 4.699 | 0.5709 | 30108.0 | 15300000 | 9600000000 | 6980000000000 | 0.4972 | 0.1660 | 0.0636 | 0.0056 | 0.1051 | 0.0237 | 0.0954 | 0.0847 | 0.1345 | 0.0790 | 0.1614 | 0.0926 | 0.1809 | 0.1400 | 0.1394 | 0.1264 | 0.0831 | 0.1072 | 0.0367 | 0.3409 | 0.0005 | 0.0013 | 0.0005 | 0.0017 | 0.0036 | 0.0031 | 0.0180 | 0.0144 | 0.0598 | 0.0423 | 0.0721 | 0.0737 | 0.0562 | 0.0471 | 0.0814 | 0.0702 | 0.7079 | 0.7462 | 0.0013 | 0.0000 | 0.0020 | 0.0007 | 0.0007 | 0.0000 | 0.0196 | 0.0156 | 0.0607 | 0.0675 | 0.0881 | 0.0896 | 0.0529 | 0.0490 | 0.0783 | 0.0888 | 0.6965 | 0.6887 | 0.0012 | 0.0012 | 0.0029 | 0.0175 | 0.0544 | 0.0807 | 0.0526 | 0.0807 | 0.7089 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 767 | 375 | | 10994 | 36702 | 317.2 | 66.33 | 88.78 | 117.60 | 238 | 259 | 276 | 292 | 309 | 327 | 346 | 373 | 410 | 0.0385 | 1412 | 0.777 | 113.02 | 23.02 | 1 | 0.0226 | 249 | 0.0006 | 70.27 | 7.726 | 0.1479 | 104984.0 | 36300000 | 13000000000 | 4880000000000 | 0.4228 | 0.2250 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0001 | 0.0125 | 0.0008 | 0.0612 | 0.0134 | 0.1259 | 0.0305 | 0.1295 | 0.0324 | 0.1666 | 0.0567 | 0.4994 | 0.8660 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0062 | 0.0003 | 0.0265 | 0.0088 | 0.0510 | 0.0177 | 0.0541 | 0.0124 | 0.0766 | 0.0239 | 0.7828 | 0.9370 | 0.0031 | 0.0102 | 0.0078 | 0.0225 | 0.0225 | 0.0758 | 0.0628 | 0.1250 | 0.1313 | 0.1557 | 0.1763 | 0.1475 | 0.1104 | 0.1025 | 0.1423 | 0.1270 | 0.3433 | 0.2336 | 0.0010 | 0.0030 | 0.0062 | 0.0294 | 0.0726 | 0.1184 | 0.1031 | 0.1345 | 0.5318 | 10 | 12 | 14 | 19 | 32 | 55 | 97 | 156 | 255 | 0.0788 | 13.52 | 4.639 | 0.5538 | 21712.5 | 8010000 | 3800000000 | 2180000000000 | 0.4103 | 0.2154 | 0.0637 | 0.0009 | 0.2390 | 0.0098 | 0.3525 | 0.1068 | 0.1643 | 0.1924 | 0.0959 | 0.2534 | 0.0480 | 0.2004 | 0.0216 | 0.1040 | 0.0113 | 0.0742 | 0.0037 | 0.0580 | 0.0002 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0012 | 0.0109 | 0.0097 | 0.0639 | 0.0507 | 0.0964 | 0.0843 | 0.0715 | 0.0616 | 0.1087 | 0.0931 | 0.6473 | 0.6989 | 0.0002 | 0.0004 | 0.0011 | 0.0016 | 0.0034 | 0.0043 | 0.0175 | 0.0189 | 0.0814 | 0.0927 | 0.1222 | 0.1338 | 0.0853 | 0.0887 | 0.1273 | 0.1253 | 0.5616 | 0.5343 | 0.0001 | 0.0004 | 0.0016 | 0.0110 | 0.0724 | 0.1147 | 0.0774 | 0.1169 | 0.6055 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 266 | 376 | | 7359 | 22890 | 393.9 | 80.84 | 63.34 | 78.23 | 293 | 321 | 344 | 366 | 388 | 412 | 437 | 465 | 502 | 0.0496 | 1136 | 1.153 | 96.80 | 33.29 | 1 | 0.0322 | 237 | 0.0011 | 27.80 | 7.040 | 0.2106 | 161669.0 | 69000000 | 30500000000 | 14000000000000 | 0.3789 | 0.2650 | 0.0002 | 0.0000 | 0.0015 | 0.0001 | 0.0032 | 0.0000 | 0.0152 | 0.0013 | 0.0513 | 0.0148 | 0.1046 | 0.0312 | 0.1114 | 0.0227 | 0.1436 | 0.0383 | 0.5691 | 0.8916 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0012 | 0.0000 | 0.0045 | 0.0004 | 0.0205 | 0.0108 | 0.0419 | 0.0204 | 0.0431 | 0.0107 | 0.0589 | 0.0187 | 0.8289 | 0.9389 | 0.0038 | 0.0124 | 0.0076 | 0.0124 | 0.0213 | 0.0661 | 0.0510 | 0.0992 | 0.1194 | 0.1488 | 0.1567 | 0.2149 | 0.1202 | 0.1281 | 0.1316 | 0.1033 | 0.3886 | 0.2149 | 0.0003 | 0.0023 | 0.0094 | 0.0185 | 0.0548 | 0.0921 | 0.0878 | 0.1112 | 0.6235 | 7 | 9 | 11 | 14 | 28 | 52 | 78 | 110 | 165 | 0.0820 | 6.27 | 4.370 | 0.6091 | 10131.0 | 2470000 | 787000000 | 303000000000 | 0.5661 | 0.0914 | 0.0148 | 0.0031 | 0.0881 | 0.0065 | 0.2066 | 0.0355 | 0.2098 | 0.0860 | 0.1801 | 0.1727 | 0.1478 | 0.1879 | 0.0804 | 0.1596 | 0.0557 | 0.1560 | 0.0166 | 0.1926 | 0.0000 | 0.0003 | 0.0006 | 0.0003 | 0.0018 | 0.0020 | 0.0116 | 0.0097 | 0.0434 | 0.0335 | 0.0720 | 0.0539 | 0.0567 | 0.0493 | 0.0830 | 0.0702 | 0.7307 | 0.7809 | 0.0009 | 0.0012 | 0.0021 | 0.0038 | 0.0055 | 0.0092 | 0.0237 | 0.0233 | 0.0528 | 0.0618 | 0.0945 | 0.0986 | 0.0705 | 0.0783 | 0.0970 | 0.1101 | 0.6531 | 0.6139 | 0.0005 | 0.0011 | 0.0028 | 0.0161 | 0.0534 | 0.0756 | 0.0638 | 0.0933 | 0.6935 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1274 | 376 | | 2281 | 2786 | 112.4 | 25.36 | 148.51 | 132.43 | 87 | 92 | 97 | 102 | 107 | 112 | 119 | 128 | 147 | 0.1637 | 456 | 1.143 | 80.71 | 26.48 | 1 | 0.0886 | 202 | 0.0048 | 13.65 | 5.717 | 0.3134 | 13272.8 | 1660000 | 220000000 | 31200000000 | 0.3671 | 0.2788 | 0.0013 | 0.0000 | 0.0019 | 0.0000 | 0.0126 | 0.0000 | 0.0265 | 0.0028 | 0.0670 | 0.0317 | 0.1062 | 0.0602 | 0.1207 | 0.0417 | 0.1903 | 0.0677 | 0.4735 | 0.7958 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0083 | 0.0000 | 0.0129 | 0.0013 | 0.0326 | 0.0193 | 0.0625 | 0.0408 | 0.0641 | 0.0171 | 0.1013 | 0.0289 | 0.7163 | 0.8926 | 0.0085 | 0.0000 | 0.0170 | 0.0176 | 0.0255 | 0.0353 | 0.0595 | 0.1000 | 0.1360 | 0.1294 | 0.1105 | 0.1471 | 0.1133 | 0.1647 | 0.1586 | 0.1353 | 0.3711 | 0.2706 | 0.0044 | 0.0065 | 0.0153 | 0.0513 | 0.0938 | 0.1134 | 0.1080 | 0.1363 | 0.4711 | 14 | 25 | 51 | 80 | 114 | 151 | 191 | 253 | 347 | 0.0074 | 29.86 | 6.106 | 0.3653 | 39586.9 | 13600000 | 5450000000 | 2400000000000 | 0.4919 | 0.1616 | 0.0228 | 0.0059 | 0.0752 | 0.0164 | 0.1686 | 0.0457 | 0.1595 | 0.0726 | 0.1800 | 0.1581 | 0.1458 | 0.1546 | 0.0911 | 0.1347 | 0.0752 | 0.1475 | 0.0820 | 0.2646 | 0.0015 | 0.0012 | 0.0044 | 0.0019 | 0.0059 | 0.0062 | 0.0236 | 0.0137 | 0.0707 | 0.0616 | 0.1216 | 0.1082 | 0.0892 | 0.0721 | 0.1054 | 0.0927 | 0.5777 | 0.6424 | 0.0033 | 0.0027 | 0.0044 | 0.0080 | 0.0142 | 0.0159 | 0.0381 | 0.0491 | 0.0817 | 0.1048 | 0.1569 | 0.1605 | 0.1122 | 0.1061 | 0.1100 | 0.1194 | 0.4793 | 0.4337 | 0.0009 | 0.0062 | 0.0133 | 0.0318 | 0.0681 | 0.1388 | 0.1149 | 0.1114 | 0.5146 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 602 | 376 | | 1156 | 4064 | 474.2 | 143.37 | 10.35 | 8.30 | 315 | 334 | 360 | 391 | 431 | 490 | 562 | 644 | 697 | 0.0947 | 385 | 1.114 | 51.86 | 18.44 | 1 | 0.1211 | 140 | 0.0033 | 11.41 | 6.019 | 0.2906 | 245360.0 | 137000000 | 81700000000 | 51000000000000 | 0.3632 | 0.2648 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0025 | 0.0010 | 0.0327 | 0.0031 | 0.0955 | 0.0462 | 0.1382 | 0.0776 | 0.1709 | 0.0525 | 0.1608 | 0.0860 | 0.3995 | 0.7324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0009 | 0.0136 | 0.0017 | 0.0339 | 0.0304 | 0.0434 | 0.0470 | 0.0542 | 0.0261 | 0.0488 | 0.0487 | 0.8049 | 0.8452 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0118 | 0.0152 | 0.0559 | 0.0812 | 0.0588 | 0.0812 | 0.0559 | 0.0558 | 0.0765 | 0.1269 | 0.7412 | 0.6396 | 0.0000 | 0.0000 | 0.0000 | 0.0041 | 0.0412 | 0.0741 | 0.0329 | 0.0658 | 0.7819 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 15 | 0.0098 | 16.68 | 5.103 | 0.3379 | 176.1 | 6409.85 | 409709 | 33400000 | 0.4040 | 0.2136 | 0.0440 | 0.0038 | 0.1040 | 0.0105 | 0.1253 | 0.0332 | 0.2015 | 0.0514 | 0.2154 | 0.0867 | 0.1685 | 0.1160 | 0.1026 | 0.1499 | 0.0330 | 0.2376 | 0.0059 | 0.3110 | 0.0174 | 0.0014 | 0.0349 | 0.0052 | 0.0418 | 0.0193 | 0.0499 | 0.0293 | 0.0774 | 0.0503 | 0.1078 | 0.0748 | 0.1139 | 0.0871 | 0.1390 | 0.1550 | 0.4179 | 0.5775 | 0.0490 | 0.0472 | 0.0672 | 0.0407 | 0.0608 | 0.0650 | 0.0572 | 0.0911 | 0.0762 | 0.1382 | 0.1016 | 0.1154 | 0.1143 | 0.1073 | 0.1661 | 0.1268 | 0.3076 | 0.2683 | 0.0357 | 0.0421 | 0.0562 | 0.0761 | 0.0860 | 0.1094 | 0.1018 | 0.1281 | 0.3645 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 987 | 380 | | 12791 | 25828 | 244.0 | 56.67 | 95.18 | 198.31 | 177 | 201 | 217 | 230 | 243 | 256 | 271 | 289 | 316 | 0.0428 | 1106 | 0.611 | 50.00 | 6.08 | 2 | 0.0081 | 104 | 0.0009 | 41.29 | 7.385 | 0.1837 | 62748.8 | 16900000 | 4720000000 | 1370000000000 | 0.4150 | 0.2225 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0040 | 0.0001 | 0.0139 | 0.0020 | 0.0437 | 0.0128 | 0.0935 | 0.0267 | 0.1037 | 0.0271 | 0.1485 | 0.0436 | 0.5911 | 0.8877 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0051 | 0.0007 | 0.0167 | 0.0075 | 0.0370 | 0.0142 | 0.0370 | 0.0105 | 0.0578 | 0.0186 | 0.8443 | 0.9484 | 0.0051 | 0.0074 | 0.0136 | 0.0297 | 0.0230 | 0.0408 | 0.0519 | 0.1169 | 0.0928 | 0.1447 | 0.1328 | 0.1855 | 0.0992 | 0.1039 | 0.1507 | 0.1169 | 0.4308 | 0.2542 | 0.0013 | 0.0041 | 0.0084 | 0.0209 | 0.0523 | 0.0900 | 0.0917 | 0.1156 | 0.6157 | 10 | 11 | 13 | 16 | 19 | 30 | 61 | 128 | 252 | 0.1445 | 34.06 | 4.024 | 0.6355 | 48384.8 | 50100000 | 70500000000 | 115000000000000 | 0.4211 | 0.2561 | 0.0753 | 0.0013 | 0.2507 | 0.0276 | 0.3011 | 0.1619 | 0.1172 | 0.1639 | 0.1051 | 0.2101 | 0.0717 | 0.1905 | 0.0362 | 0.0921 | 0.0291 | 0.0768 | 0.0135 | 0.0758 | 0.0001 | 0.0002 | 0.0003 | 0.0001 | 0.0021 | 0.0012 | 0.0147 | 0.0116 | 0.0679 | 0.0616 | 0.1162 | 0.1005 | 0.0657 | 0.0596 | 0.1024 | 0.0930 | 0.6306 | 0.6721 | 0.0002 | 0.0012 | 0.0012 | 0.0028 | 0.0041 | 0.0058 | 0.0225 | 0.0271 | 0.0797 | 0.0776 | 0.1234 | 0.1387 | 0.0808 | 0.0856 | 0.1154 | 0.1264 | 0.5727 | 0.5349 | 0.0002 | 0.0013 | 0.0034 | 0.0168 | 0.0750 | 0.1186 | 0.0738 | 0.1066 | 0.6045 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1039 | 381 | | 3800 | 9893 | 128.9 | 35.24 | 177.58 | 105.97 | 91 | 99 | 107 | 113 | 121 | 131 | 142 | 156 | 177 | 0.0668 | 661 | 1.078 | 92.18 | 30.89 | 1 | 0.0611 | 232 | 0.0025 | 19.96 | 6.337 | 0.2693 | 17862.2 | 2670000 | 431000000 | 74800000000 | 0.4064 | 0.2310 | 0.0020 | 0.0000 | 0.0049 | 0.0000 | 0.0133 | 0.0003 | 0.0405 | 0.0023 | 0.0968 | 0.0290 | 0.1532 | 0.0582 | 0.1502 | 0.0603 | 0.1789 | 0.0892 | 0.3602 | 0.7607 | 0.0007 | 0.0000 | 0.0028 | 0.0000 | 0.0032 | 0.0000 | 0.0142 | 0.0011 | 0.0383 | 0.0165 | 0.0663 | 0.0315 | 0.0670 | 0.0221 | 0.1018 | 0.0464 | 0.7057 | 0.8824 | 0.0013 | 0.0000 | 0.0025 | 0.0150 | 0.0226 | 0.0240 | 0.0477 | 0.1201 | 0.1206 | 0.1592 | 0.1520 | 0.1742 | 0.1244 | 0.1171 | 0.1595 | 0.1411 | 0.3693 | 0.2492 | 0.0019 | 0.0038 | 0.0107 | 0.0239 | 0.0704 | 0.1157 | 0.0855 | 0.1157 | 0.5723 | 56 | 84 | 110 | 137 | 161 | 189 | 217 | 254 | 321 | 0.0018 | 32.40 | 6.743 | 0.2735 | 42762.9 | 12800000 | 4530000000 | 1830000000000 | 0.5224 | 0.1428 | 0.0069 | 0.0004 | 0.0360 | 0.0032 | 0.1033 | 0.0123 | 0.1645 | 0.0379 | 0.1920 | 0.0917 | 0.1882 | 0.1453 | 0.1446 | 0.1523 | 0.1037 | 0.1707 | 0.0608 | 0.3863 | 0.0007 | 0.0000 | 0.0011 | 0.0007 | 0.0051 | 0.0014 | 0.0161 | 0.0074 | 0.0562 | 0.0314 | 0.0904 | 0.0636 | 0.0907 | 0.0624 | 0.1212 | 0.0865 | 0.6186 | 0.7466 | 0.0019 | 0.0053 | 0.0061 | 0.0144 | 0.0200 | 0.0202 | 0.0517 | 0.0554 | 0.0950 | 0.1391 | 0.1363 | 0.1464 | 0.1266 | 0.1165 | 0.1315 | 0.1310 | 0.4309 | 0.3717 | 0.0011 | 0.0046 | 0.0090 | 0.0264 | 0.0790 | 0.1152 | 0.1061 | 0.1299 | 0.5287 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 404 | 381 | | 364 | 11109 | 91.1 | 12.14 | 8.23 | 2.31 | 76 | 80 | 84 | 87 | 91 | 94 | 97 | 101 | 107 | 0.0564 | 627 | 0.370 | 126.83 | 26.31 | 1 | 1.2060 | 439 | 0.0718 | 0.71 | 2.815 | 0.7088 | 8437.9 | 795470 | 76300000 | 7430000000 | 0.3908 | 0.2100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0192 | 0.0055 | 0.0895 | 0.0714 | 0.1789 | 0.1099 | 0.1278 | 0.0604 | 0.1917 | 0.1044 | 0.3930 | 0.6484 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0117 | 0.0055 | 0.0787 | 0.0714 | 0.1254 | 0.1099 | 0.0671 | 0.0604 | 0.1195 | 0.1044 | 0.5977 | 0.6484 | 0.0333 | 0.0000 | 0.0333 | 0.0000 | 0.0667 | 0.0000 | 0.2667 | 0.0000 | 0.1333 | 0.0000 | 0.2000 | 0.0000 | 0.0667 | 0.0000 | 0.0333 | 0.0000 | 0.1667 | 0.0000 | 0.0055 | 0.0055 | 0.0055 | 0.0546 | 0.1421 | 0.1694 | 0.1038 | 0.1639 | 0.3497 | 5 | 6 | 7 | 8 | 8 | 9 | 9 | 10 | 11 | 0.2651 | 0.45 | 1.038 | 0.6298 | 73.1 | 692.301 | 6934.55 | 73026.4 | 0.5150 | 0.1470 | 0.0084 | 0.0000 | 0.0454 | 0.0006 | 0.1209 | 0.0027 | 0.2055 | 0.0101 | 0.2489 | 0.0293 | 0.2133 | 0.0743 | 0.1150 | 0.1788 | 0.0368 | 0.3510 | 0.0059 | 0.3532 | 0.0002 | 0.0000 | 0.0024 | 0.0000 | 0.0090 | 0.0002 | 0.0345 | 0.0025 | 0.0902 | 0.0128 | 0.1613 | 0.0328 | 0.2251 | 0.0673 | 0.2757 | 0.2320 | 0.2014 | 0.6524 | 0.0871 | 0.3913 | 0.1762 | 0.3337 | 0.2103 | 0.1554 | 0.1847 | 0.0633 | 0.1500 | 0.0368 | 0.1089 | 0.0161 | 0.0537 | 0.0035 | 0.0237 | 0.0000 | 0.0054 | 0.0000 | 0.0034 | 0.0150 | 0.0465 | 0.1072 | 0.1765 | 0.2248 | 0.1975 | 0.1520 | 0.0770 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 919 | 384 | | 3864 | 10644 | 549.9 | 111.66 | 119.69 | 118.07 | 401 | 445 | 482 | 515 | 547 | 581 | 614 | 651 | 699 | 0.0750 | 798 | 1.029 | 90.48 | 35.85 | 1 | 0.0663 | 256 | 0.0007 | 70.72 | 7.491 | 0.1370 | 314839.0 | 187000000 | 115000000000 | 72500000000000 | 0.4423 | 0.2000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0000 | 0.0131 | 0.0027 | 0.0668 | 0.0158 | 0.1439 | 0.0363 | 0.1447 | 0.0328 | 0.1681 | 0.0507 | 0.4596 | 0.8617 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0021 | 0.0277 | 0.0136 | 0.0621 | 0.0288 | 0.0535 | 0.0207 | 0.0701 | 0.0298 | 0.7804 | 0.9050 | 0.0029 | 0.0519 | 0.0114 | 0.0390 | 0.0157 | 0.0390 | 0.0672 | 0.1818 | 0.1502 | 0.2338 | 0.1788 | 0.1948 | 0.1288 | 0.1169 | 0.1431 | 0.0519 | 0.3019 | 0.0909 | 0.0000 | 0.0010 | 0.0037 | 0.0199 | 0.0659 | 0.1141 | 0.0795 | 0.1141 | 0.6018 | 11 | 15 | 23 | 44 | 81 | 122 | 165 | 219 | 293 | 0.0192 | 16.46 | 5.675 | 0.4317 | 28266.0 | 8580000 | 3000000000 | 1160000000000 | 0.4622 | 0.1810 | 0.0320 | 0.0021 | 0.1652 | 0.0111 | 0.2654 | 0.0848 | 0.1446 | 0.1330 | 0.1611 | 0.2072 | 0.1002 | 0.1734 | 0.0666 | 0.1199 | 0.0411 | 0.1273 | 0.0238 | 0.1413 | 0.0004 | 0.0004 | 0.0002 | 0.0004 | 0.0026 | 0.0020 | 0.0100 | 0.0065 | 0.0573 | 0.0464 | 0.0915 | 0.0770 | 0.0713 | 0.0525 | 0.1045 | 0.0919 | 0.6622 | 0.7230 | 0.0003 | 0.0006 | 0.0019 | 0.0016 | 0.0054 | 0.0048 | 0.0200 | 0.0279 | 0.0764 | 0.0901 | 0.1300 | 0.1487 | 0.0978 | 0.0983 | 0.1230 | 0.1376 | 0.5451 | 0.4903 | 0.0005 | 0.0016 | 0.0023 | 0.0137 | 0.0615 | 0.1121 | 0.0896 | 0.1246 | 0.5942 | ||
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 981 | 384 | | 5976 | 15063 | 375.2 | 139.04 | 87.22 | 138.43 | 122 | 252 | 332 | 379 | 411 | 436 | 459 | 488 | 529 | 0.0690 | 1040 | 1.006 | 89.27 | 27.02 | 6 | 0.0370 | 221 | 0.0008 | 30.99 | 7.402 | 0.2347 | 160087.0 | 72700000 | 34300000000 | 16600000000000 | 0.3898 | 0.2387 | 0.0000 | 0.0007 | 0.0017 | 0.0002 | 0.0067 | 0.0009 | 0.0168 | 0.0037 | 0.0750 | 0.0273 | 0.1215 | 0.0375 | 0.1056 | 0.0371 | 0.1567 | 0.0526 | 0.5159 | 0.8400 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0010 | 0.0162 | 0.0143 | 0.0270 | 0.0202 | 0.0191 | 0.0149 | 0.0299 | 0.0212 | 0.9067 | 0.9283 | 0.0010 | 0.0079 | 0.0044 | 0.0111 | 0.0092 | 0.0142 | 0.0247 | 0.0190 | 0.0499 | 0.0774 | 0.0727 | 0.0900 | 0.0751 | 0.0979 | 0.0931 | 0.1327 | 0.6699 | 0.5498 | 0.0000 | 0.0000 | 0.0003 | 0.0047 | 0.0261 | 0.0387 | 0.0368 | 0.0506 | 0.8428 | 6 | 9 | 12 | 16 | 25 | 42 | 68 | 128 | 272 | 0.0676 | 12.92 | 4.513 | 0.5910 | 26768.0 | 12200000 | 6560000000 | 3860000000000 | 0.6432 | 0.1082 | 0.0291 | 0.0037 | 0.1315 | 0.0140 | 0.2008 | 0.0494 | 0.1526 | 0.1090 | 0.1345 | 0.1747 | 0.1305 | 0.1850 | 0.0723 | 0.1072 | 0.0773 | 0.1235 | 0.0713 | 0.2335 | 0.0004 | 0.0011 | 0.0020 | 0.0030 | 0.0027 | 0.0032 | 0.0162 | 0.0112 | 0.0605 | 0.0539 | 0.0900 | 0.0723 | 0.0693 | 0.0632 | 0.0924 | 0.0883 | 0.6664 | 0.7038 | 0.0017 | 0.0010 | 0.0017 | 0.0041 | 0.0049 | 0.0073 | 0.0171 | 0.0188 | 0.0713 | 0.0786 | 0.0991 | 0.0958 | 0.0739 | 0.0856 | 0.1026 | 0.1117 | 0.6275 | 0.5969 | 0.0016 | 0.0028 | 0.0041 | 0.0173 | 0.0693 | 0.0929 | 0.0745 | 0.0962 | 0.6412 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 789 | 385 | | 5318 | 5252 | 117.1 | 28.29 | 183.50 | 149.81 | 88 | 95 | 101 | 106 | 111 | 118 | 126 | 135 | 153 | 0.1359 | 714 | 1.185 | 99.25 | 31.11 | 1 | 0.0440 | 234 | 0.0038 | 12.98 | 5.962 | 0.3134 | 14501.7 | 1920000 | 277000000 | 44100000000 | 0.4157 | 0.2302 | 0.0009 | 0.0000 | 0.0020 | 0.0000 | 0.0054 | 0.0000 | 0.0148 | 0.0014 | 0.0594 | 0.0200 | 0.1213 | 0.0451 | 0.1410 | 0.0401 | 0.1627 | 0.0615 | 0.4926 | 0.8319 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0032 | 0.0000 | 0.0092 | 0.0002 | 0.0304 | 0.0127 | 0.0533 | 0.0251 | 0.0612 | 0.0134 | 0.0839 | 0.0215 | 0.7570 | 0.9271 | 0.0036 | 0.0085 | 0.0107 | 0.0142 | 0.0130 | 0.0342 | 0.0627 | 0.0883 | 0.1456 | 0.2023 | 0.1692 | 0.1766 | 0.0994 | 0.0855 | 0.1669 | 0.1595 | 0.3290 | 0.2308 | 0.0013 | 0.0072 | 0.0103 | 0.0354 | 0.0752 | 0.1150 | 0.1115 | 0.1352 | 0.5090 | 34 | 56 | 79 | 108 | 140 | 180 | 233 | 298 | 398 | 0.0028 | 51.84 | 6.696 | 0.3006 | 56111.0 | 22900000 | 11200000000 | 6260000000000 | 0.5751 | 0.1077 | 0.0275 | 0.0017 | 0.1066 | 0.0098 | 0.2575 | 0.0574 | 0.1760 | 0.1074 | 0.1701 | 0.1895 | 0.1401 | 0.1959 | 0.0671 | 0.1430 | 0.0299 | 0.1310 | 0.0251 | 0.1643 | 0.0008 | 0.0000 | 0.0024 | 0.0010 | 0.0052 | 0.0029 | 0.0226 | 0.0226 | 0.0755 | 0.0634 | 0.1156 | 0.0976 | 0.0898 | 0.0789 | 0.1017 | 0.0957 | 0.5866 | 0.6379 | 0.0012 | 0.0007 | 0.0024 | 0.0052 | 0.0125 | 0.0163 | 0.0458 | 0.0570 | 0.0903 | 0.1117 | 0.1729 | 0.1805 | 0.1028 | 0.1139 | 0.1147 | 0.1220 | 0.4575 | 0.3928 | 0.0005 | 0.0044 | 0.0068 | 0.0311 | 0.0856 | 0.1465 | 0.0934 | 0.1226 | 0.5090 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 338 | 385 | | 6192 | 19742 | 233.9 | 53.78 | 137.63 | 180.46 | 171 | 188 | 203 | 216 | 228 | 242 | 256 | 273 | 303 | 0.0555 | 1095 | 1.184 | 93.43 | 33.02 | 1 | 0.0363 | 225 | 0.0009 | 46.43 | 7.247 | 0.1652 | 57591.1 | 14900000 | 4100000000 | 1190000000000 | 0.3895 | 0.2646 | 0.0000 | 0.0000 | 0.0018 | 0.0002 | 0.0041 | 0.0002 | 0.0216 | 0.0019 | 0.0685 | 0.0188 | 0.1277 | 0.0445 | 0.1508 | 0.0419 | 0.1815 | 0.0664 | 0.4442 | 0.8263 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0002 | 0.0094 | 0.0011 | 0.0292 | 0.0133 | 0.0619 | 0.0277 | 0.0581 | 0.0198 | 0.0873 | 0.0284 | 0.7507 | 0.9093 | 0.0076 | 0.0147 | 0.0066 | 0.0265 | 0.0199 | 0.0265 | 0.0939 | 0.1088 | 0.1319 | 0.1559 | 0.1717 | 0.1706 | 0.1063 | 0.0971 | 0.1395 | 0.1294 | 0.3226 | 0.2706 | 0.0007 | 0.0025 | 0.0074 | 0.0298 | 0.0895 | 0.1288 | 0.1057 | 0.1541 | 0.4816 | 12 | 14 | 17 | 23 | 43 | 88 | 167 | 264 | 387 | 0.0461 | 28.23 | 5.244 | 0.4903 | 51505.6 | 27300000 | 17700000000 | 13300000000000 | 0.5436 | 0.1197 | 0.0589 | 0.0037 | 0.2135 | 0.0134 | 0.3305 | 0.1158 | 0.1622 | 0.1818 | 0.0910 | 0.2308 | 0.0773 | 0.1922 | 0.0344 | 0.1091 | 0.0245 | 0.0820 | 0.0077 | 0.0712 | 0.0000 | 0.0004 | 0.0004 | 0.0007 | 0.0018 | 0.0016 | 0.0103 | 0.0074 | 0.0488 | 0.0426 | 0.0827 | 0.0744 | 0.0564 | 0.0488 | 0.0887 | 0.0770 | 0.7108 | 0.7471 | 0.0003 | 0.0002 | 0.0010 | 0.0013 | 0.0015 | 0.0013 | 0.0126 | 0.0158 | 0.0614 | 0.0710 | 0.1023 | 0.1142 | 0.0737 | 0.0805 | 0.1031 | 0.1182 | 0.6440 | 0.5975 | 0.0002 | 0.0003 | 0.0017 | 0.0124 | 0.0554 | 0.0907 | 0.0685 | 0.0965 | 0.6744 |