High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 550 | 347 | | 2625 | 7570 | 364.6 | 100.61 | 57.27 | 93.59 | 229 | 271 | 313 | 338 | 359 | 381 | 405 | 462 | 513 | 0.0856 | 648 | 0.595 | 111.40 | 19.31 | 7 | 0.1051 | 276 | 0.0012 | 33.64 | 6.958 | 0.2138 | 143052.0 | 59700000 | 26200000000 | 12000000000000 | 0.3697 | 0.2506 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0007 | 0.0023 | 0.0162 | 0.0079 | 0.0855 | 0.0410 | 0.1179 | 0.0843 | 0.0929 | 0.0531 | 0.0899 | 0.0754 | 0.5969 | 0.7346 | 0.0000 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0035 | 0.0016 | 0.0333 | 0.0276 | 0.0455 | 0.0470 | 0.0414 | 0.0272 | 0.0510 | 0.0404 | 0.8253 | 0.8549 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0000 | 0.0216 | 0.0225 | 0.0396 | 0.0722 | 0.1367 | 0.1075 | 0.2086 | 0.0690 | 0.1223 | 0.1043 | 0.1295 | 0.6244 | 0.3309 | 0.0000 | 0.0008 | 0.0048 | 0.0191 | 0.0590 | 0.0901 | 0.0726 | 0.0989 | 0.6547 | 8 | 10 | 12 | 14 | 18 | 23 | 38 | 87 | 161 | 0.1461 | 5.86 | 3.394 | 0.7357 | 12038.0 | 4300000 | 1950000000 | 1010000000000 | 0.6794 | 0.0692 | 0.0238 | 0.0092 | 0.0506 | 0.0184 | 0.1131 | 0.0407 | 0.1310 | 0.0512 | 0.2292 | 0.1168 | 0.2083 | 0.1444 | 0.1280 | 0.1470 | 0.0893 | 0.1745 | 0.0268 | 0.2979 | 0.0019 | 0.0025 | 0.0014 | 0.0038 | 0.0068 | 0.0059 | 0.0106 | 0.0106 | 0.0323 | 0.0317 | 0.0651 | 0.0571 | 0.0458 | 0.0440 | 0.0719 | 0.0693 | 0.7641 | 0.7751 | 0.0006 | 0.0000 | 0.0012 | 0.0006 | 0.0035 | 0.0075 | 0.0098 | 0.0106 | 0.0368 | 0.0399 | 0.0725 | 0.0761 | 0.0478 | 0.0586 | 0.0725 | 0.0773 | 0.7553 | 0.7294 | 0.0005 | 0.0011 | 0.0053 | 0.0090 | 0.0329 | 0.0638 | 0.0515 | 0.0733 | 0.7625 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 552 | 584 | | 9730 | 22960 | 539.9 | 116.17 | 146.55 | 125.01 | 407 | 442 | 468 | 494 | 522 | 550 | 584 | 629 | 705 | 0.0487 | 1118 | 1.101 | 111.89 | 44.42 | 1 | 0.0312 | 304 | 0.0009 | 44.66 | 7.368 | 0.1782 | 304940.0 | 180000000 | 112000000000 | 72500000000000 | 0.4444 | 0.1987 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0022 | 0.0000 | 0.0102 | 0.0014 | 0.0583 | 0.0160 | 0.1054 | 0.0336 | 0.1103 | 0.0294 | 0.1389 | 0.0462 | 0.5744 | 0.8733 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0010 | 0.0000 | 0.0048 | 0.0000 | 0.0270 | 0.0090 | 0.0515 | 0.0177 | 0.0520 | 0.0107 | 0.0667 | 0.0200 | 0.7970 | 0.9425 | 0.0006 | 0.0034 | 0.0104 | 0.0068 | 0.0097 | 0.0273 | 0.0420 | 0.0528 | 0.0981 | 0.1772 | 0.1510 | 0.1772 | 0.1139 | 0.1244 | 0.1364 | 0.1516 | 0.4379 | 0.2794 | 0.0009 | 0.0038 | 0.0081 | 0.0268 | 0.0648 | 0.0997 | 0.0955 | 0.1138 | 0.5866 | 26 | 46 | 69 | 93 | 116 | 141 | 173 | 217 | 307 | 0.0087 | 14.33 | 5.634 | 0.4373 | 37104.1 | 13800000 | 6720000000 | 4000000000000 | 0.5360 | 0.1367 | 0.0163 | 0.0005 | 0.0637 | 0.0048 | 0.1580 | 0.0328 | 0.1548 | 0.0671 | 0.1728 | 0.1313 | 0.1646 | 0.1718 | 0.1121 | 0.1434 | 0.0945 | 0.1555 | 0.0632 | 0.2927 | 0.0004 | 0.0002 | 0.0009 | 0.0007 | 0.0048 | 0.0016 | 0.0166 | 0.0115 | 0.0663 | 0.0489 | 0.1136 | 0.0904 | 0.0895 | 0.0739 | 0.1218 | 0.1031 | 0.5861 | 0.6696 | 0.0010 | 0.0037 | 0.0046 | 0.0085 | 0.0097 | 0.0132 | 0.0331 | 0.0351 | 0.1031 | 0.1074 | 0.1483 | 0.1604 | 0.1084 | 0.1050 | 0.1378 | 0.1369 | 0.4538 | 0.4299 | 0.0014 | 0.0023 | 0.0070 | 0.0228 | 0.0831 | 0.1367 | 0.1048 | 0.1260 | 0.5159 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 553 | 850 | | 1687 | 2459 | 300.5 | 204.06 | 15.65 | 29.61 | 110 | 143 | 172 | 196 | 226 | 271 | 333 | 444 | 654 | 0.1684 | 414 | 0.726 | 89.00 | 15.23 | 2 | 0.1114 | 188 | 0.0012 | 52.86 | 6.939 | 0.2192 | 131887.0 | 75200000 | 49500000000 | 35300000000000 | 0.3308 | 0.2934 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0059 | 0.0039 | 0.0676 | 0.0130 | 0.1618 | 0.0649 | 0.2176 | 0.1104 | 0.1294 | 0.0909 | 0.1147 | 0.1078 | 0.3029 | 0.6091 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0102 | 0.0089 | 0.0422 | 0.0337 | 0.0588 | 0.0452 | 0.0409 | 0.0425 | 0.0537 | 0.0558 | 0.7941 | 0.8113 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0000 | 0.0045 | 0.0056 | 0.0543 | 0.0446 | 0.0860 | 0.0864 | 0.0294 | 0.0362 | 0.0633 | 0.0585 | 0.7579 | 0.7688 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0434 | 0.0701 | 0.0484 | 0.0668 | 0.7613 | 6 | 7 | 8 | 9 | 10 | 11 | 11 | 13 | 16 | 0.6120 | 0.70 | 1.147 | 0.8761 | 1121.1 | 209476 | 49200000 | 12700000000 | 0.5069 | 0.1463 | 0.1731 | 0.0340 | 0.1621 | 0.0635 | 0.1264 | 0.1020 | 0.1978 | 0.1422 | 0.1264 | 0.1592 | 0.1209 | 0.1494 | 0.0604 | 0.1476 | 0.0275 | 0.1127 | 0.0055 | 0.0894 | 0.1136 | 0.0296 | 0.0971 | 0.0553 | 0.0531 | 0.0872 | 0.1081 | 0.1153 | 0.1117 | 0.1379 | 0.1026 | 0.1254 | 0.0861 | 0.1347 | 0.1081 | 0.1160 | 0.2198 | 0.1986 | 0.0110 | 0.0000 | 0.0385 | 0.0060 | 0.0055 | 0.0060 | 0.0220 | 0.0482 | 0.1154 | 0.1024 | 0.1264 | 0.1265 | 0.1154 | 0.1205 | 0.1209 | 0.1325 | 0.4451 | 0.4578 | 0.0618 | 0.0579 | 0.0734 | 0.0463 | 0.0888 | 0.1004 | 0.0811 | 0.1197 | 0.3707 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 555 | 532 | | 3465 | 14759 | 319.8 | 107.54 | 6.73 | 2.27 | 198 | 221 | 243 | 273 | 310 | 350 | 374 | 394 | 435 | 0.0700 | 1033 | 1.221 | 77.39 | 27.66 | 2 | 0.0543 | 188 | 0.0057 | 5.18 | 5.576 | 0.4523 | 113808.0 | 45100000 | 19800000000 | 9650000000000 | 0.4430 | 0.1901 | 0.0028 | 0.0000 | 0.0063 | 0.0000 | 0.0042 | 0.0017 | 0.0245 | 0.0068 | 0.0756 | 0.0345 | 0.1436 | 0.0519 | 0.1289 | 0.0420 | 0.1646 | 0.0615 | 0.4496 | 0.8016 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0004 | 0.0012 | 0.0105 | 0.0031 | 0.0285 | 0.0271 | 0.0558 | 0.0389 | 0.0378 | 0.0249 | 0.0470 | 0.0408 | 0.8187 | 0.8639 | 0.0106 | 0.0000 | 0.0153 | 0.0071 | 0.0188 | 0.0035 | 0.0259 | 0.0390 | 0.0506 | 0.0887 | 0.0576 | 0.0957 | 0.0682 | 0.0780 | 0.0988 | 0.0993 | 0.6541 | 0.5887 | 0.0000 | 0.0024 | 0.0018 | 0.0152 | 0.0328 | 0.0425 | 0.0334 | 0.0468 | 0.8251 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0844 | 0.35 | 0.898 | 0.3300 | 50.5 | 413.246 | 3661.4 | 35082.4 | 0.5392 | 0.1292 | 0.0068 | 0.0003 | 0.0451 | 0.0042 | 0.1067 | 0.0171 | 0.1894 | 0.0476 | 0.2341 | 0.0957 | 0.2205 | 0.1698 | 0.1356 | 0.2507 | 0.0525 | 0.2678 | 0.0093 | 0.1466 | 0.0014 | 0.0002 | 0.0128 | 0.0021 | 0.0344 | 0.0077 | 0.0739 | 0.0219 | 0.1043 | 0.0520 | 0.1474 | 0.0981 | 0.1623 | 0.1436 | 0.2138 | 0.2421 | 0.2497 | 0.4324 | 0.1133 | 0.1976 | 0.1372 | 0.2142 | 0.1664 | 0.1783 | 0.1654 | 0.1636 | 0.1518 | 0.1123 | 0.1186 | 0.0744 | 0.0801 | 0.0372 | 0.0458 | 0.0160 | 0.0213 | 0.0064 | 0.0167 | 0.0531 | 0.0922 | 0.1109 | 0.1310 | 0.1500 | 0.1506 | 0.1588 | 0.1366 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 558 | 297 | | 5154 | 21541 | 500.5 | 100.92 | 62.27 | 98.68 | 379 | 413 | 441 | 465 | 489 | 516 | 545 | 583 | 643 | 0.0452 | 974 | 1.154 | 82.42 | 31.26 | 1 | 0.0415 | 214 | 0.0008 | 54.34 | 7.369 | 0.1710 | 260702.0 | 141000000 | 79400000000 | 46200000000000 | 0.4202 | 0.2271 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0017 | 0.0002 | 0.0098 | 0.0012 | 0.0500 | 0.0161 | 0.1015 | 0.0368 | 0.0980 | 0.0279 | 0.1322 | 0.0328 | 0.6056 | 0.8850 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0006 | 0.0245 | 0.0117 | 0.0493 | 0.0242 | 0.0433 | 0.0125 | 0.0646 | 0.0189 | 0.8118 | 0.9320 | 0.0012 | 0.0000 | 0.0048 | 0.0048 | 0.0119 | 0.0193 | 0.0523 | 0.1063 | 0.1010 | 0.1401 | 0.1354 | 0.2415 | 0.0926 | 0.0918 | 0.1330 | 0.1594 | 0.4679 | 0.2367 | 0.0004 | 0.0034 | 0.0068 | 0.0256 | 0.0631 | 0.1062 | 0.0981 | 0.1207 | 0.5755 | 7 | 8 | 9 | 11 | 13 | 22 | 54 | 107 | 186 | 0.1524 | 8.90 | 3.882 | 0.6556 | 13615.0 | 4670000 | 2040000000 | 1060000000000 | 0.5472 | 0.1233 | 0.0212 | 0.0048 | 0.0778 | 0.0100 | 0.2184 | 0.0291 | 0.2431 | 0.0917 | 0.2007 | 0.1943 | 0.1344 | 0.2273 | 0.0654 | 0.1586 | 0.0309 | 0.1369 | 0.0080 | 0.1473 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0018 | 0.0020 | 0.0078 | 0.0083 | 0.0383 | 0.0319 | 0.0619 | 0.0584 | 0.0403 | 0.0398 | 0.0605 | 0.0521 | 0.7895 | 0.8065 | 0.0000 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0038 | 0.0112 | 0.0113 | 0.0443 | 0.0457 | 0.0656 | 0.0707 | 0.0474 | 0.0532 | 0.0740 | 0.0811 | 0.7534 | 0.7324 | 0.0003 | 0.0000 | 0.0021 | 0.0080 | 0.0402 | 0.0651 | 0.0435 | 0.0623 | 0.7784 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 559 | 397 | | 4059 | 4987 | 157.3 | 43.64 | 166.74 | 137.41 | 113 | 123 | 131 | 139 | 148 | 157 | 168 | 187 | 216 | 0.1313 | 655 | 1.114 | 90.61 | 28.23 | 1 | 0.0532 | 216 | 0.0019 | 30.80 | 6.626 | 0.2263 | 26652.8 | 4910000 | 989000000 | 219000000000 | 0.4120 | 0.2290 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0082 | 0.0005 | 0.0341 | 0.0027 | 0.0928 | 0.0269 | 0.1428 | 0.0626 | 0.1670 | 0.0541 | 0.1833 | 0.0802 | 0.3697 | 0.7729 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0039 | 0.0002 | 0.0135 | 0.0015 | 0.0410 | 0.0154 | 0.0693 | 0.0336 | 0.0738 | 0.0197 | 0.1013 | 0.0351 | 0.6956 | 0.8945 | 0.0051 | 0.0053 | 0.0064 | 0.0132 | 0.0128 | 0.0079 | 0.0370 | 0.1164 | 0.1392 | 0.1138 | 0.1520 | 0.2063 | 0.1137 | 0.1190 | 0.1494 | 0.1349 | 0.3844 | 0.2831 | 0.0006 | 0.0043 | 0.0188 | 0.0389 | 0.0832 | 0.1269 | 0.1014 | 0.1263 | 0.4997 | 31 | 49 | 69 | 94 | 126 | 164 | 210 | 272 | 369 | 0.0031 | 48.39 | 6.631 | 0.2926 | 46678.1 | 17300000 | 7530000000 | 3680000000000 | 0.5082 | 0.1638 | 0.0343 | 0.0038 | 0.1220 | 0.0131 | 0.1792 | 0.0451 | 0.1868 | 0.1264 | 0.1753 | 0.1496 | 0.1334 | 0.2034 | 0.0940 | 0.1508 | 0.0445 | 0.1189 | 0.0305 | 0.1890 | 0.0004 | 0.0007 | 0.0034 | 0.0014 | 0.0038 | 0.0031 | 0.0290 | 0.0239 | 0.0720 | 0.0560 | 0.1195 | 0.1000 | 0.0909 | 0.0796 | 0.1136 | 0.1058 | 0.5673 | 0.6295 | 0.0025 | 0.0023 | 0.0019 | 0.0023 | 0.0120 | 0.0232 | 0.0340 | 0.0518 | 0.1051 | 0.1044 | 0.1385 | 0.1353 | 0.0906 | 0.1067 | 0.1284 | 0.1276 | 0.4871 | 0.4462 | 0.0000 | 0.0061 | 0.0096 | 0.0289 | 0.0851 | 0.1327 | 0.0917 | 0.1155 | 0.5304 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 559 | 324 | | 5411 | 13979 | 127.3 | 31.31 | 130.32 | 107.34 | 89 | 100 | 109 | 117 | 124 | 132 | 141 | 151 | 168 | 0.0763 | 1067 | 1.014 | 110.37 | 33.29 | 4 | 0.0521 | 282 | 0.0023 | 18.78 | 6.376 | 0.2715 | 17190.0 | 2460000 | 372000000 | 59300000000 | 0.4432 | 0.2029 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0080 | 0.0014 | 0.0234 | 0.0043 | 0.0765 | 0.0204 | 0.1540 | 0.0553 | 0.1534 | 0.0488 | 0.1918 | 0.0784 | 0.3919 | 0.7915 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0012 | 0.0002 | 0.0077 | 0.0019 | 0.0329 | 0.0131 | 0.0659 | 0.0324 | 0.0624 | 0.0240 | 0.0845 | 0.0388 | 0.7452 | 0.8896 | 0.0068 | 0.0157 | 0.0087 | 0.0105 | 0.0243 | 0.0393 | 0.0816 | 0.0785 | 0.1516 | 0.1387 | 0.1642 | 0.2042 | 0.1127 | 0.1230 | 0.1399 | 0.1728 | 0.3100 | 0.2173 | 0.0012 | 0.0027 | 0.0054 | 0.0287 | 0.0794 | 0.1239 | 0.1084 | 0.1328 | 0.5174 | 28 | 45 | 62 | 81 | 100 | 125 | 156 | 198 | 271 | 0.0030 | 34.90 | 6.603 | 0.3130 | 28505.8 | 8880000 | 3530000000 | 1650000000000 | 0.5202 | 0.1472 | 0.0186 | 0.0011 | 0.0727 | 0.0086 | 0.1643 | 0.0338 | 0.1423 | 0.0684 | 0.1790 | 0.1246 | 0.1651 | 0.1717 | 0.1245 | 0.1441 | 0.0808 | 0.1616 | 0.0530 | 0.2861 | 0.0010 | 0.0005 | 0.0022 | 0.0019 | 0.0066 | 0.0044 | 0.0196 | 0.0131 | 0.0583 | 0.0437 | 0.1079 | 0.0808 | 0.0793 | 0.0712 | 0.1135 | 0.0987 | 0.6115 | 0.6857 | 0.0021 | 0.0027 | 0.0062 | 0.0046 | 0.0119 | 0.0161 | 0.0307 | 0.0402 | 0.0858 | 0.1010 | 0.1424 | 0.1586 | 0.1108 | 0.1077 | 0.1350 | 0.1324 | 0.4750 | 0.4367 | 0.0015 | 0.0050 | 0.0110 | 0.0224 | 0.0660 | 0.1195 | 0.1011 | 0.1256 | 0.5478 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 559 | 386 | | 734 | 10113 | 39.1 | 16.71 | 545.35 | 386.84 | 28 | 29 | 30 | 31 | 32 | 34 | 37 | 45 | 64 | 0.0518 | 524 | 0.593 | 209.07 | 60.01 | 2 | 0.9973 | 732 | 0.0308 | 4.90 | 4.259 | 0.5054 | 1809.2 | 103002 | 7120000 | 567000000 | 0.4029 | 0.2328 | 0.0252 | 0.0000 | 0.0540 | 0.0000 | 0.0755 | 0.0000 | 0.1295 | 0.0174 | 0.1403 | 0.0616 | 0.1799 | 0.0585 | 0.1403 | 0.0932 | 0.1475 | 0.0853 | 0.1079 | 0.6840 | 0.0170 | 0.0000 | 0.0365 | 0.0000 | 0.0462 | 0.0000 | 0.0754 | 0.0136 | 0.0730 | 0.0409 | 0.0900 | 0.0368 | 0.0681 | 0.0587 | 0.1095 | 0.0559 | 0.4842 | 0.7940 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0376 | 0.0200 | 0.0752 | 0.1500 | 0.0827 | 0.0400 | 0.0977 | 0.1100 | 0.0752 | 0.1200 | 0.6316 | 0.5600 | 0.0000 | 0.0052 | 0.0103 | 0.0155 | 0.0619 | 0.0825 | 0.0825 | 0.0928 | 0.6495 | 110 | 186 | 267 | 361 | 473 | 591 | 720 | 874 | 1078 | 0.0014 | 42.72 | 7.230 | 0.2482 | 447031.0 | 456000000 | 536000000000 | 698000000000000 | 0.4409 | 0.2151 | 0.0049 | 0.0008 | 0.0213 | 0.0030 | 0.1079 | 0.0134 | 0.1706 | 0.0422 | 0.2262 | 0.1218 | 0.2011 | 0.1874 | 0.1226 | 0.1487 | 0.0823 | 0.1769 | 0.0632 | 0.3059 | 0.0004 | 0.0003 | 0.0013 | 0.0006 | 0.0037 | 0.0034 | 0.0144 | 0.0101 | 0.0397 | 0.0346 | 0.0744 | 0.0570 | 0.0498 | 0.0461 | 0.0699 | 0.0684 | 0.7464 | 0.7795 | 0.0017 | 0.0015 | 0.0017 | 0.0015 | 0.0043 | 0.0070 | 0.0218 | 0.0278 | 0.0519 | 0.0725 | 0.0930 | 0.1147 | 0.0904 | 0.1118 | 0.1106 | 0.1336 | 0.6246 | 0.5296 | 0.0007 | 0.0052 | 0.0059 | 0.0197 | 0.0437 | 0.0749 | 0.0656 | 0.0837 | 0.7007 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 560 | 270 | | 5568 | 18268 | 433.5 | 92.93 | 137.20 | 136.94 | 324 | 352 | 376 | 397 | 422 | 446 | 477 | 510 | 564 | 0.0541 | 989 | 1.182 | 95.60 | 36.50 | 1 | 0.0449 | 250 | 0.0012 | 33.93 | 7.010 | 0.1946 | 196527.0 | 93100000 | 46100000000 | 23700000000000 | 0.4332 | 0.2136 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0020 | 0.0002 | 0.0140 | 0.0011 | 0.0717 | 0.0192 | 0.1259 | 0.0400 | 0.1320 | 0.0390 | 0.1664 | 0.0581 | 0.4877 | 0.8422 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0064 | 0.0000 | 0.0304 | 0.0128 | 0.0556 | 0.0229 | 0.0530 | 0.0152 | 0.0754 | 0.0265 | 0.7781 | 0.9225 | 0.0031 | 0.0070 | 0.0071 | 0.0245 | 0.0224 | 0.0280 | 0.0671 | 0.1294 | 0.1180 | 0.1993 | 0.1699 | 0.2133 | 0.1282 | 0.1084 | 0.1506 | 0.1434 | 0.3337 | 0.1469 | 0.0020 | 0.0016 | 0.0052 | 0.0290 | 0.0708 | 0.1225 | 0.0982 | 0.1301 | 0.5406 | 20 | 35 | 55 | 76 | 97 | 124 | 159 | 209 | 290 | 0.0125 | 11.31 | 5.396 | 0.4946 | 37572.9 | 16400000 | 9620000000 | 6730000000000 | 0.5560 | 0.1152 | 0.0139 | 0.0011 | 0.0448 | 0.0071 | 0.1227 | 0.0245 | 0.1370 | 0.0568 | 0.1652 | 0.1234 | 0.1675 | 0.1608 | 0.1217 | 0.1315 | 0.1118 | 0.1516 | 0.1154 | 0.3433 | 0.0013 | 0.0001 | 0.0016 | 0.0026 | 0.0052 | 0.0039 | 0.0169 | 0.0131 | 0.0498 | 0.0475 | 0.0829 | 0.0732 | 0.0663 | 0.0599 | 0.0861 | 0.0802 | 0.6900 | 0.7194 | 0.0015 | 0.0007 | 0.0029 | 0.0034 | 0.0061 | 0.0079 | 0.0209 | 0.0274 | 0.0672 | 0.0758 | 0.1087 | 0.1185 | 0.0846 | 0.0902 | 0.1045 | 0.1152 | 0.6036 | 0.5609 | 0.0021 | 0.0021 | 0.0044 | 0.0190 | 0.0539 | 0.0970 | 0.0768 | 0.0992 | 0.6453 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 561 | 247 | | 4445 | 15033 | 466.1 | 65.09 | 63.62 | 138.06 | 379 | 413 | 433 | 450 | 466 | 481 | 499 | 521 | 551 | 0.0559 | 840 | 1.186 | 46.40 | 17.49 | 1 | 0.0270 | 120 | 0.0015 | 34.76 | 6.820 | 0.2169 | 221513.0 | 107000000 | 52800000000 | 26400000000000 | 0.4116 | 0.2311 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0035 | 0.0002 | 0.0355 | 0.0137 | 0.0646 | 0.0248 | 0.0635 | 0.0142 | 0.0910 | 0.0205 | 0.7407 | 0.9266 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0002 | 0.0221 | 0.0137 | 0.0368 | 0.0248 | 0.0314 | 0.0142 | 0.0456 | 0.0187 | 0.8620 | 0.9284 | 0.0110 | 1.0000 | 0.0192 | 0.0000 | 0.0219 | 0.0000 | 0.0959 | 0.0000 | 0.1479 | 0.0000 | 0.1726 | 0.0000 | 0.1397 | 0.0000 | 0.1288 | 0.0000 | 0.2630 | 0.0000 | 0.0004 | 0.0036 | 0.0085 | 0.0278 | 0.0732 | 0.0996 | 0.0961 | 0.1302 | 0.5606 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 57 | 200 | 0.2619 | 11.61 | 3.053 | 0.7574 | 23105.5 | 14100000 | 11000000000 | 10100000000000 | 0.4691 | 0.1844 | 0.0363 | 0.0081 | 0.0726 | 0.0208 | 0.0726 | 0.0728 | 0.1501 | 0.0786 | 0.1622 | 0.1110 | 0.1671 | 0.1260 | 0.1574 | 0.1191 | 0.1090 | 0.1445 | 0.0726 | 0.3191 | 0.0003 | 0.0012 | 0.0013 | 0.0030 | 0.0023 | 0.0044 | 0.0077 | 0.0094 | 0.0229 | 0.0195 | 0.0265 | 0.0301 | 0.0245 | 0.0248 | 0.0368 | 0.0387 | 0.8777 | 0.8689 | 0.0011 | 0.0000 | 0.0011 | 0.0004 | 0.0022 | 0.0024 | 0.0108 | 0.0091 | 0.0238 | 0.0234 | 0.0309 | 0.0313 | 0.0313 | 0.0317 | 0.0395 | 0.0527 | 0.8593 | 0.8490 | 0.0003 | 0.0007 | 0.0048 | 0.0104 | 0.0214 | 0.0308 | 0.0235 | 0.0443 | 0.8637 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 563 | 523 | | 7584 | 13597 | 292.9 | 83.06 | 182.75 | 174.84 | 193 | 209 | 226 | 248 | 286 | 322 | 349 | 375 | 408 | 0.0785 | 1067 | 1.101 | 127.77 | 42.45 | 1 | 0.0407 | 309 | 0.0016 | 18.42 | 6.833 | 0.3003 | 92706.4 | 31400000 | 11200000000 | 4180000000000 | 0.4037 | 0.2427 | 0.0029 | 0.0000 | 0.0068 | 0.0012 | 0.0184 | 0.0023 | 0.0417 | 0.0059 | 0.0763 | 0.0230 | 0.1000 | 0.0516 | 0.1051 | 0.0428 | 0.1263 | 0.0614 | 0.5225 | 0.8120 | 0.0010 | 0.0000 | 0.0022 | 0.0011 | 0.0026 | 0.0007 | 0.0070 | 0.0022 | 0.0191 | 0.0112 | 0.0291 | 0.0256 | 0.0275 | 0.0134 | 0.0388 | 0.0299 | 0.8726 | 0.9160 | 0.0014 | 0.0000 | 0.0023 | 0.0000 | 0.0073 | 0.0000 | 0.0200 | 0.0000 | 0.0514 | 0.0000 | 0.0906 | 0.0000 | 0.0915 | 0.0000 | 0.1138 | 0.0000 | 0.6218 | 0.0000 | 0.0000 | 0.0005 | 0.0005 | 0.0055 | 0.0191 | 0.0372 | 0.0372 | 0.0563 | 0.8437 | 21 | 37 | 61 | 91 | 127 | 171 | 226 | 307 | 431 | 0.0098 | 23.73 | 6.012 | 0.4274 | 63963.5 | 31000000 | 18200000000 | 12200000000000 | 0.4970 | 0.1734 | 0.0146 | 0.0008 | 0.0690 | 0.0059 | 0.1458 | 0.0403 | 0.1437 | 0.0687 | 0.1813 | 0.1390 | 0.1557 | 0.1647 | 0.0967 | 0.1352 | 0.0810 | 0.1280 | 0.1123 | 0.3175 | 0.0002 | 0.0000 | 0.0006 | 0.0014 | 0.0034 | 0.0032 | 0.0156 | 0.0128 | 0.0523 | 0.0433 | 0.0827 | 0.0651 | 0.0658 | 0.0553 | 0.0969 | 0.0768 | 0.6825 | 0.7421 | 0.0007 | 0.0011 | 0.0009 | 0.0049 | 0.0082 | 0.0066 | 0.0238 | 0.0255 | 0.0714 | 0.0887 | 0.1100 | 0.1319 | 0.0872 | 0.0887 | 0.1249 | 0.1379 | 0.5728 | 0.5147 | 0.0002 | 0.0029 | 0.0057 | 0.0176 | 0.0629 | 0.0975 | 0.0805 | 0.1129 | 0.6198 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 564 | 431 | | 338 | 1164 | 102.2 | 15.22 | 7.58 | 3.30 | 84 | 88 | 92 | 95 | 102 | 108 | 112 | 115 | 121 | 0.2259 | 263 | 0.523 | 92.70 | 19.72 | 2 | 0.8195 | 277 | 0.0741 | 0.65 | 2.916 | 0.7228 | 10676.7 | 1140000 | 124000000 | 13800000000 | 0.3677 | 0.2665 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0035 | 0.0000 | 0.0070 | 0.0090 | 0.0662 | 0.0448 | 0.1533 | 0.0985 | 0.0732 | 0.0507 | 0.1150 | 0.0836 | 0.5784 | 0.7134 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0063 | 0.0089 | 0.0508 | 0.0444 | 0.1111 | 0.0947 | 0.0381 | 0.0385 | 0.0730 | 0.0621 | 0.7175 | 0.7515 | 0.0000 | 0.0000 | 0.0357 | 0.0000 | 0.0357 | 1.0000 | 0.1071 | 0.0000 | 0.1786 | 0.0000 | 0.1786 | 0.0000 | 0.1429 | 0.0000 | 0.1071 | 0.0000 | 0.2143 | 0.0000 | 0.0059 | 0.0000 | 0.0000 | 0.0296 | 0.0710 | 0.0888 | 0.0888 | 0.0947 | 0.6213 | 5 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 10 | 0.1160 | 0.40 | 1.049 | 0.4095 | 68.4 | 808.275 | 13870.1 | 338018 | 0.5218 | 0.1263 | 0.0138 | 0.0000 | 0.1041 | 0.0030 | 0.2004 | 0.0099 | 0.2338 | 0.0338 | 0.1847 | 0.0746 | 0.1493 | 0.1014 | 0.0727 | 0.1690 | 0.0393 | 0.3052 | 0.0020 | 0.3032 | 0.0071 | 0.0000 | 0.0454 | 0.0000 | 0.0894 | 0.0055 | 0.1504 | 0.0193 | 0.1660 | 0.0654 | 0.1943 | 0.1096 | 0.1191 | 0.1436 | 0.1121 | 0.2818 | 0.1163 | 0.3748 | 0.2041 | 0.0875 | 0.1735 | 0.1250 | 0.0561 | 0.1250 | 0.0765 | 0.0500 | 0.1173 | 0.0625 | 0.1276 | 0.1750 | 0.0918 | 0.1625 | 0.0918 | 0.1000 | 0.0612 | 0.1125 | 0.0463 | 0.1305 | 0.1347 | 0.1705 | 0.1347 | 0.1200 | 0.0968 | 0.0758 | 0.0905 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 564 | 834 | | 5735 | 9264 | 386.5 | 90.39 | 113.25 | 134.91 | 287 | 312 | 332 | 351 | 371 | 393 | 423 | 457 | 512 | 0.0955 | 885 | 1.153 | 94.87 | 36.50 | 1 | 0.0424 | 243 | 0.0010 | 39.47 | 7.169 | 0.1888 | 157556.0 | 67800000 | 30700000000 | 14700000000000 | 0.4429 | 0.2115 | 0.0008 | 0.0000 | 0.0019 | 0.0006 | 0.0036 | 0.0017 | 0.0202 | 0.0044 | 0.0679 | 0.0189 | 0.1422 | 0.0466 | 0.1486 | 0.0405 | 0.1705 | 0.0615 | 0.4443 | 0.8259 | 0.0004 | 0.0000 | 0.0011 | 0.0002 | 0.0024 | 0.0009 | 0.0105 | 0.0021 | 0.0358 | 0.0126 | 0.0710 | 0.0308 | 0.0693 | 0.0219 | 0.0813 | 0.0324 | 0.7282 | 0.8991 | 0.0076 | 0.0105 | 0.0123 | 0.0026 | 0.0123 | 0.0211 | 0.0550 | 0.0632 | 0.0920 | 0.1395 | 0.1404 | 0.1447 | 0.0920 | 0.1289 | 0.1262 | 0.1421 | 0.4620 | 0.3474 | 0.0012 | 0.0032 | 0.0097 | 0.0385 | 0.0838 | 0.1187 | 0.0956 | 0.1126 | 0.5367 | 9 | 11 | 13 | 22 | 52 | 96 | 147 | 211 | 309 | 0.0380 | 20.61 | 5.347 | 0.4709 | 31025.6 | 11600000 | 5240000000 | 2690000000000 | 0.6389 | 0.0617 | 0.0305 | 0.0023 | 0.1469 | 0.0170 | 0.2362 | 0.0978 | 0.1627 | 0.1213 | 0.1345 | 0.1582 | 0.0949 | 0.1687 | 0.0983 | 0.1201 | 0.0588 | 0.1125 | 0.0373 | 0.2021 | 0.0005 | 0.0000 | 0.0003 | 0.0002 | 0.0016 | 0.0026 | 0.0128 | 0.0086 | 0.0534 | 0.0432 | 0.0826 | 0.0776 | 0.0631 | 0.0491 | 0.1081 | 0.0918 | 0.6777 | 0.7269 | 0.0000 | 0.0008 | 0.0010 | 0.0008 | 0.0054 | 0.0051 | 0.0217 | 0.0249 | 0.0633 | 0.0785 | 0.1178 | 0.1224 | 0.0796 | 0.0890 | 0.1260 | 0.1383 | 0.5852 | 0.5404 | 0.0000 | 0.0006 | 0.0027 | 0.0183 | 0.0601 | 0.0914 | 0.0787 | 0.1213 | 0.6269 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 566 | 807 | | 4751 | 7725 | 404.9 | 192.17 | 127.70 | 196.98 | 142 | 186 | 268 | 341 | 396 | 464 | 540 | 611 | 670 | 0.1111 | 858 | 1.078 | 54.04 | 18.87 | 1 | 0.0280 | 133 | 0.0027 | 8.16 | 6.352 | 0.3795 | 200834.0 | 112000000 | 66500000000 | 41200000000000 | 0.3420 | 0.2744 | 0.0000 | 0.0005 | 0.0008 | 0.0005 | 0.0016 | 0.0005 | 0.0219 | 0.0064 | 0.0926 | 0.0401 | 0.1300 | 0.0724 | 0.1024 | 0.0519 | 0.1446 | 0.0738 | 0.5061 | 0.7540 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0003 | 0.0189 | 0.0153 | 0.0314 | 0.0269 | 0.0245 | 0.0136 | 0.0453 | 0.0266 | 0.8762 | 0.9173 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0011 | 0.0008 | 0.0050 | 0.0111 | 0.0296 | 0.0325 | 0.0369 | 0.0507 | 0.0335 | 0.0428 | 0.0464 | 0.0642 | 0.8475 | 0.7971 | 0.0000 | 0.0004 | 0.0000 | 0.0104 | 0.0265 | 0.0370 | 0.0313 | 0.0487 | 0.8456 | 7 | 9 | 11 | 16 | 28 | 63 | 121 | 222 | 412 | 0.0706 | 13.58 | 4.145 | 0.5200 | 55103.2 | 34600000 | 26500000000 | 23100000000000 | 0.6752 | 0.0630 | 0.0314 | 0.0009 | 0.1458 | 0.0204 | 0.2288 | 0.0814 | 0.1513 | 0.1230 | 0.1439 | 0.1748 | 0.1328 | 0.1832 | 0.0627 | 0.1221 | 0.0424 | 0.1240 | 0.0609 | 0.1702 | 0.0008 | 0.0000 | 0.0008 | 0.0003 | 0.0020 | 0.0007 | 0.0106 | 0.0115 | 0.0701 | 0.0687 | 0.1133 | 0.0965 | 0.0830 | 0.0767 | 0.1251 | 0.1154 | 0.5943 | 0.6302 | 0.0015 | 0.0000 | 0.0035 | 0.0028 | 0.0095 | 0.0084 | 0.0160 | 0.0302 | 0.0845 | 0.0878 | 0.1191 | 0.1270 | 0.1046 | 0.1079 | 0.1251 | 0.1208 | 0.5363 | 0.5151 | 0.0000 | 0.0013 | 0.0013 | 0.0191 | 0.0756 | 0.1250 | 0.0894 | 0.1299 | 0.5583 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 568 | 142 | | 3390 | 3676 | 488.2 | 76.89 | 55.99 | 95.47 | 384 | 420 | 448 | 473 | 493 | 513 | 533 | 556 | 587 | 0.1317 | 484 | 0.859 | 109.18 | 23.32 | 5 | 0.0752 | 255 | 0.0012 | 41.51 | 6.959 | 0.2091 | 244289.0 | 125000000 | 65200000000 | 34600000000000 | 0.4456 | 0.2022 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0133 | 0.0009 | 0.0451 | 0.0139 | 0.0863 | 0.0237 | 0.0833 | 0.0160 | 0.1064 | 0.0261 | 0.6638 | 0.9194 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0050 | 0.0009 | 0.0220 | 0.0139 | 0.0441 | 0.0237 | 0.0414 | 0.0154 | 0.0588 | 0.0231 | 0.8284 | 0.9230 | 0.0028 | 0.0000 | 0.0113 | 1.0000 | 0.0395 | 0.0000 | 0.1073 | 0.0000 | 0.1638 | 0.0000 | 0.2147 | 0.0000 | 0.1243 | 0.0000 | 0.1356 | 0.0000 | 0.2006 | 0.0000 | 0.0006 | 0.0017 | 0.0045 | 0.0195 | 0.0658 | 0.1155 | 0.1016 | 0.1267 | 0.5642 | 9 | 11 | 12 | 14 | 17 | 20 | 25 | 75 | 169 | 0.1554 | 6.68 | 3.147 | 0.7267 | 12247.2 | 4240000 | 1770000000 | 834000000000 | 0.4752 | 0.1492 | 0.0192 | 0.0284 | 0.0769 | 0.0355 | 0.1731 | 0.1277 | 0.3462 | 0.1489 | 0.1346 | 0.1915 | 0.1346 | 0.1773 | 0.1154 | 0.1206 | 0.0000 | 0.0709 | 0.0000 | 0.0993 | 0.0000 | 0.0046 | 0.0025 | 0.0058 | 0.0012 | 0.0116 | 0.0037 | 0.0127 | 0.0160 | 0.0197 | 0.0197 | 0.0313 | 0.0271 | 0.0174 | 0.0406 | 0.0440 | 0.8892 | 0.8530 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0028 | 0.0039 | 0.0083 | 0.0211 | 0.0221 | 0.0316 | 0.0456 | 0.0395 | 0.0415 | 0.0684 | 0.0692 | 0.8329 | 0.8105 | 0.0000 | 0.0000 | 0.0013 | 0.0038 | 0.0189 | 0.0215 | 0.0278 | 0.0556 | 0.8712 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 571 | 922 | | 4617 | 8322 | 491.0 | 95.75 | 198.40 | 274.48 | 372 | 405 | 431 | 459 | 485 | 511 | 541 | 573 | 621 | 0.0908 | 756 | 1.217 | 121.30 | 48.70 | 1 | 0.0682 | 315 | 0.0006 | 68.44 | 7.576 | 0.1426 | 250279.0 | 132000000 | 72100000000 | 40600000000000 | 0.4178 | 0.2313 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0002 | 0.0112 | 0.0025 | 0.0586 | 0.0169 | 0.1189 | 0.0373 | 0.1287 | 0.0263 | 0.1587 | 0.0443 | 0.5217 | 0.8725 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0064 | 0.0011 | 0.0309 | 0.0133 | 0.0554 | 0.0279 | 0.0492 | 0.0168 | 0.0717 | 0.0251 | 0.7855 | 0.9157 | 0.0040 | 0.0000 | 0.0081 | 0.0000 | 0.0256 | 0.0000 | 0.0823 | 0.0000 | 0.1107 | 0.0000 | 0.1741 | 0.0000 | 0.1039 | 0.0000 | 0.1323 | 0.0000 | 0.3590 | 0.0000 | 0.0005 | 0.0023 | 0.0059 | 0.0244 | 0.0765 | 0.1199 | 0.0851 | 0.1231 | 0.5624 | 15 | 20 | 25 | 38 | 68 | 118 | 188 | 348 | 633 | 0.0340 | 31.16 | 5.359 | 0.5201 | 114691.0 | 92700000 | 87100000000 | 90400000000000 | 0.3987 | 0.2243 | 0.0214 | 0.0007 | 0.1193 | 0.0152 | 0.2370 | 0.0550 | 0.1330 | 0.0774 | 0.1361 | 0.1527 | 0.1055 | 0.2069 | 0.0826 | 0.1122 | 0.0841 | 0.1165 | 0.0810 | 0.2634 | 0.0004 | 0.0003 | 0.0029 | 0.0015 | 0.0022 | 0.0021 | 0.0122 | 0.0114 | 0.0561 | 0.0418 | 0.0820 | 0.0749 | 0.0557 | 0.0523 | 0.0805 | 0.0737 | 0.7080 | 0.7419 | 0.0005 | 0.0000 | 0.0014 | 0.0010 | 0.0056 | 0.0031 | 0.0118 | 0.0118 | 0.0592 | 0.0536 | 0.0870 | 0.1050 | 0.0602 | 0.0551 | 0.0827 | 0.0881 | 0.6916 | 0.6823 | 0.0008 | 0.0017 | 0.0033 | 0.0124 | 0.0541 | 0.0880 | 0.0570 | 0.0843 | 0.6985 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 576 | 951 | | 438 | 2028 | 54.0 | 7.53 | 156.62 | 225.49 | 45 | 48 | 49 | 51 | 54 | 55 | 57 | 60 | 63 | 0.1686 | 342 | 0.895 | 78.01 | 22.20 | 1 | 0.4566 | 200 | 0.0096 | 10.55 | 4.855 | 0.3142 | 2971.3 | 166797 | 9560000 | 559000000 | 0.3875 | 0.2379 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0023 | 0.0262 | 0.0092 | 0.0945 | 0.0624 | 0.1260 | 0.0901 | 0.1811 | 0.0693 | 0.2520 | 0.1085 | 0.3123 | 0.6582 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0023 | 0.0193 | 0.0091 | 0.0578 | 0.0594 | 0.0988 | 0.0868 | 0.1012 | 0.0548 | 0.1518 | 0.0868 | 0.5639 | 0.7009 | 0.1765 | 0.0000 | 0.1765 | 0.2000 | 0.0588 | 0.2000 | 0.1765 | 0.6000 | 0.1176 | 0.0000 | 0.0294 | 0.0000 | 0.1765 | 0.0000 | 0.0882 | 0.0000 | 0.0000 | 0.0000 | 0.0136 | 0.0318 | 0.0227 | 0.0773 | 0.1364 | 0.1364 | 0.1500 | 0.2091 | 0.2227 | 17 | 21 | 28 | 41 | 64 | 99 | 142 | 241 | 425 | 0.0260 | 58.20 | 5.100 | 0.4350 | 75349.7 | 58100000 | 55000000000 | 57800000000000 | 0.4831 | 0.1439 | 0.1056 | 0.0000 | 0.2609 | 0.0221 | 0.2050 | 0.1838 | 0.0870 | 0.1569 | 0.1242 | 0.1936 | 0.0870 | 0.1201 | 0.0683 | 0.0760 | 0.0435 | 0.1176 | 0.0186 | 0.1299 | 0.0030 | 0.0000 | 0.0030 | 0.0036 | 0.0151 | 0.0059 | 0.0256 | 0.0119 | 0.0935 | 0.0973 | 0.1704 | 0.1269 | 0.0905 | 0.0973 | 0.1297 | 0.1329 | 0.4691 | 0.5243 | 0.0020 | 0.0000 | 0.0060 | 0.0069 | 0.0159 | 0.0207 | 0.0239 | 0.0345 | 0.1076 | 0.1310 | 0.1853 | 0.1816 | 0.1036 | 0.0989 | 0.1474 | 0.1402 | 0.4084 | 0.3862 | 0.0000 | 0.0035 | 0.0159 | 0.0265 | 0.1044 | 0.1805 | 0.0973 | 0.1274 | 0.4442 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 577 | 529 | | 6874 | 21430 | 274.4 | 54.77 | 116.67 | 134.04 | 206 | 226 | 242 | 256 | 270 | 284 | 301 | 322 | 348 | 0.0497 | 1066 | 0.952 | 129.08 | 32.53 | 1 | 0.0428 | 294 | 0.0008 | 54.60 | 7.392 | 0.1620 | 78288.9 | 23200000 | 7120000000 | 2260000000000 | 0.4124 | 0.2339 | 0.0007 | 0.0000 | 0.0004 | 0.0000 | 0.0024 | 0.0002 | 0.0146 | 0.0009 | 0.0620 | 0.0167 | 0.1265 | 0.0357 | 0.1468 | 0.0339 | 0.1774 | 0.0560 | 0.4691 | 0.8567 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0052 | 0.0007 | 0.0245 | 0.0114 | 0.0505 | 0.0239 | 0.0545 | 0.0147 | 0.0759 | 0.0202 | 0.7879 | 0.9290 | 0.0068 | 0.0346 | 0.0101 | 0.0260 | 0.0245 | 0.1126 | 0.0785 | 0.1472 | 0.1647 | 0.2338 | 0.1976 | 0.1515 | 0.1309 | 0.1126 | 0.1512 | 0.1169 | 0.2356 | 0.0649 | 0.0012 | 0.0000 | 0.0080 | 0.0316 | 0.0807 | 0.1133 | 0.1072 | 0.1308 | 0.5272 | 10 | 13 | 16 | 28 | 55 | 99 | 154 | 222 | 315 | 0.0595 | 13.88 | 5.027 | 0.5286 | 31578.4 | 11600000 | 5190000000 | 2690000000000 | 0.5015 | 0.1536 | 0.0506 | 0.0016 | 0.2117 | 0.0180 | 0.3416 | 0.0886 | 0.1686 | 0.1769 | 0.1002 | 0.2501 | 0.0717 | 0.1846 | 0.0372 | 0.1200 | 0.0151 | 0.0904 | 0.0032 | 0.0698 | 0.0001 | 0.0000 | 0.0006 | 0.0005 | 0.0015 | 0.0008 | 0.0076 | 0.0083 | 0.0547 | 0.0435 | 0.0986 | 0.0770 | 0.0711 | 0.0601 | 0.1113 | 0.0927 | 0.6546 | 0.7171 | 0.0003 | 0.0007 | 0.0017 | 0.0016 | 0.0030 | 0.0034 | 0.0156 | 0.0219 | 0.0765 | 0.0905 | 0.1334 | 0.1420 | 0.0961 | 0.1062 | 0.1363 | 0.1430 | 0.5370 | 0.4906 | 0.0003 | 0.0010 | 0.0023 | 0.0117 | 0.0625 | 0.1168 | 0.0835 | 0.1295 | 0.5924 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 580 | 433 | | 1493 | 7000 | 280.3 | 39.92 | 26.94 | 45.70 | 230 | 246 | 259 | 269 | 278 | 289 | 298 | 312 | 333 | 0.0730 | 511 | 0.722 | 72.57 | 16.03 | 1 | 0.1092 | 163 | 0.0044 | 8.62 | 5.687 | 0.3499 | 80150.8 | 23400000 | 6950000000 | 2110000000000 | 0.4223 | 0.2148 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0007 | 0.0385 | 0.0235 | 0.0577 | 0.0450 | 0.0513 | 0.0215 | 0.0810 | 0.0403 | 0.7642 | 0.8690 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0007 | 0.0246 | 0.0221 | 0.0377 | 0.0442 | 0.0261 | 0.0181 | 0.0399 | 0.0328 | 0.8681 | 0.8821 | 0.0226 | 0.2000 | 0.0150 | 0.2000 | 0.0526 | 0.4000 | 0.0677 | 0.2000 | 0.0602 | 0.0000 | 0.1053 | 0.0000 | 0.0902 | 0.0000 | 0.1278 | 0.0000 | 0.4586 | 0.0000 | 0.0014 | 0.0014 | 0.0069 | 0.0220 | 0.0495 | 0.0755 | 0.0975 | 0.1319 | 0.6140 | 7 | 8 | 9 | 10 | 12 | 15 | 20 | 33 | 57 | 0.2933 | 1.67 | 2.358 | 0.8342 | 2814.2 | 777978 | 343000000 | 188000000000 | 0.6091 | 0.1098 | 0.0437 | 0.0353 | 0.0542 | 0.0453 | 0.0822 | 0.0637 | 0.1014 | 0.0599 | 0.1294 | 0.0860 | 0.1451 | 0.1083 | 0.1521 | 0.1045 | 0.1573 | 0.1421 | 0.1346 | 0.3548 | 0.0065 | 0.0172 | 0.0101 | 0.0192 | 0.0081 | 0.0204 | 0.0141 | 0.0188 | 0.0252 | 0.0337 | 0.0348 | 0.0425 | 0.0403 | 0.0357 | 0.0685 | 0.0665 | 0.7924 | 0.7459 | 0.0035 | 0.0050 | 0.0042 | 0.0084 | 0.0099 | 0.0168 | 0.0156 | 0.0218 | 0.0453 | 0.0536 | 0.0545 | 0.0662 | 0.0630 | 0.0679 | 0.1288 | 0.1274 | 0.6752 | 0.6329 | 0.0024 | 0.0047 | 0.0082 | 0.0141 | 0.0294 | 0.0500 | 0.0488 | 0.1106 | 0.7318 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 582 | 250 | | 4778 | 14966 | 457.7 | 96.53 | 89.22 | 140.57 | 342 | 375 | 399 | 423 | 446 | 472 | 503 | 544 | 595 | 0.0565 | 845 | 1.104 | 103.97 | 26.91 | 1 | 0.0479 | 229 | 0.0010 | 47.20 | 7.130 | 0.1892 | 218847.0 | 109000000 | 56500000000 | 30300000000000 | 0.4000 | 0.2511 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0045 | 0.0004 | 0.0175 | 0.0009 | 0.0684 | 0.0206 | 0.1267 | 0.0402 | 0.1305 | 0.0356 | 0.1626 | 0.0566 | 0.4879 | 0.8457 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0048 | 0.0004 | 0.0342 | 0.0151 | 0.0585 | 0.0274 | 0.0650 | 0.0193 | 0.0849 | 0.0278 | 0.7521 | 0.9101 | 0.0078 | 0.0314 | 0.0045 | 0.0314 | 0.0201 | 0.0419 | 0.0536 | 0.0576 | 0.1095 | 0.2042 | 0.1430 | 0.1937 | 0.1128 | 0.1152 | 0.1296 | 0.1571 | 0.4190 | 0.1675 | 0.0018 | 0.0041 | 0.0115 | 0.0290 | 0.0809 | 0.1241 | 0.0938 | 0.1159 | 0.5389 | 5 | 7 | 8 | 10 | 12 | 21 | 71 | 181 | 309 | 0.1594 | 14.47 | 4.050 | 0.6108 | 27717.5 | 11400000 | 5320000000 | 2730000000000 | 0.4192 | 0.2070 | 0.0600 | 0.0054 | 0.1989 | 0.0109 | 0.2420 | 0.0827 | 0.1839 | 0.1544 | 0.1407 | 0.2452 | 0.0882 | 0.1962 | 0.0563 | 0.0990 | 0.0169 | 0.0990 | 0.0131 | 0.1072 | 0.0002 | 0.0002 | 0.0007 | 0.0002 | 0.0009 | 0.0008 | 0.0083 | 0.0087 | 0.0333 | 0.0322 | 0.0492 | 0.0453 | 0.0395 | 0.0316 | 0.0572 | 0.0465 | 0.8108 | 0.8345 | 0.0000 | 0.0005 | 0.0018 | 0.0005 | 0.0025 | 0.0013 | 0.0079 | 0.0070 | 0.0370 | 0.0436 | 0.0631 | 0.0662 | 0.0484 | 0.0554 | 0.0667 | 0.0759 | 0.7725 | 0.7495 | 0.0000 | 0.0000 | 0.0019 | 0.0086 | 0.0378 | 0.0557 | 0.0431 | 0.0633 | 0.7896 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 584 | 956 | | 603 | 2463 | 406.2 | 49.35 | 106.45 | 171.74 | 341 | 360 | 374 | 391 | 405 | 421 | 434 | 449 | 475 | 0.1397 | 344 | 0.741 | 102.83 | 29.41 | 1 | 0.4809 | 290 | 0.0035 | 18.91 | 5.793 | 0.2498 | 167409.0 | 70000000 | 29700000000 | 12800000000000 | 0.3625 | 0.2807 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0037 | 0.0017 | 0.0608 | 0.0415 | 0.0958 | 0.0630 | 0.0608 | 0.0315 | 0.1105 | 0.0481 | 0.6648 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0034 | 0.0017 | 0.0444 | 0.0415 | 0.0650 | 0.0630 | 0.0342 | 0.0315 | 0.0581 | 0.0481 | 0.7932 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0952 | 0.0000 | 0.1190 | 0.0000 | 0.1905 | 0.0000 | 0.2381 | 0.0000 | 0.1429 | 0.0000 | 0.1190 | 0.0000 | 0.0952 | 0.0000 | 0.0000 | 0.0000 | 0.0101 | 0.0269 | 0.0842 | 0.1010 | 0.1010 | 0.1279 | 0.5488 | 8 | 10 | 11 | 13 | 15 | 30 | 107 | 188 | 310 | 0.1805 | 23.87 | 3.814 | 0.6487 | 40814.5 | 22400000 | 14400000000 | 10100000000000 | 0.5211 | 0.1245 | 0.0866 | 0.0122 | 0.0551 | 0.0528 | 0.1417 | 0.1098 | 0.2205 | 0.1138 | 0.1575 | 0.1301 | 0.1890 | 0.1707 | 0.0787 | 0.1220 | 0.0236 | 0.1260 | 0.0472 | 0.1626 | 0.0012 | 0.0000 | 0.0000 | 0.0047 | 0.0025 | 0.0070 | 0.0149 | 0.0117 | 0.0532 | 0.0493 | 0.0916 | 0.0880 | 0.0668 | 0.0563 | 0.0693 | 0.0599 | 0.7005 | 0.7230 | 0.0015 | 0.0017 | 0.0000 | 0.0033 | 0.0132 | 0.0132 | 0.0264 | 0.0281 | 0.0543 | 0.0677 | 0.1189 | 0.1254 | 0.0764 | 0.0858 | 0.0837 | 0.1073 | 0.6256 | 0.5677 | 0.0000 | 0.0013 | 0.0040 | 0.0148 | 0.0617 | 0.1074 | 0.0671 | 0.0832 | 0.6604 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 587 | 223 | | 7211 | 12710 | 578.3 | 90.41 | 89.40 | 111.01 | 452 | 510 | 547 | 574 | 591 | 608 | 625 | 646 | 680 | 0.0629 | 799 | 0.795 | 89.56 | 23.85 | 3 | 0.0344 | 248 | 0.0009 | 62.64 | 7.370 | 0.1958 | 342572.0 | 207000000 | 127000000000 | 79600000000000 | 0.4491 | 0.1905 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0041 | 0.0004 | 0.0233 | 0.0117 | 0.0460 | 0.0246 | 0.0364 | 0.0110 | 0.0566 | 0.0202 | 0.8320 | 0.9321 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0004 | 0.0145 | 0.0117 | 0.0316 | 0.0246 | 0.0189 | 0.0110 | 0.0268 | 0.0179 | 0.9057 | 0.9343 | 0.0091 | 1.0000 | 0.0146 | 0.0000 | 0.0183 | 0.0000 | 0.0530 | 0.0000 | 0.0804 | 0.0000 | 0.1005 | 0.0000 | 0.1024 | 0.0000 | 0.0951 | 0.0000 | 0.5265 | 0.0000 | 0.0002 | 0.0019 | 0.0045 | 0.0124 | 0.0426 | 0.0660 | 0.0670 | 0.0881 | 0.7172 | 10 | 14 | 19 | 27 | 40 | 63 | 103 | 156 | 234 | 0.0268 | 20.05 | 5.200 | 0.4970 | 20313.0 | 7180000 | 3310000000 | 1810000000000 | 0.4322 | 0.2068 | 0.0263 | 0.0009 | 0.1259 | 0.0110 | 0.2488 | 0.0568 | 0.1902 | 0.1088 | 0.1746 | 0.1845 | 0.1190 | 0.2039 | 0.0576 | 0.1352 | 0.0371 | 0.1325 | 0.0205 | 0.1664 | 0.0006 | 0.0000 | 0.0021 | 0.0011 | 0.0049 | 0.0034 | 0.0148 | 0.0150 | 0.0490 | 0.0449 | 0.0884 | 0.0752 | 0.0504 | 0.0554 | 0.0762 | 0.0747 | 0.7136 | 0.7303 | 0.0008 | 0.0006 | 0.0022 | 0.0034 | 0.0048 | 0.0079 | 0.0202 | 0.0248 | 0.0619 | 0.0657 | 0.0967 | 0.1116 | 0.0695 | 0.0730 | 0.0948 | 0.0920 | 0.6491 | 0.6210 | 0.0000 | 0.0017 | 0.0031 | 0.0174 | 0.0513 | 0.0911 | 0.0613 | 0.0830 | 0.6913 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 590 | 585 | | 6499 | 12657 | 474.1 | 105.05 | 39.01 | 84.66 | 344 | 379 | 410 | 438 | 465 | 494 | 525 | 566 | 619 | 0.0658 | 833 | 0.436 | 85.09 | 24.33 | 2 | 0.0495 | 322 | 0.0005 | 98.02 | 7.849 | 0.1181 | 235821.0 | 123000000 | 66600000000 | 37500000000000 | 0.4186 | 0.2373 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0081 | 0.0002 | 0.0234 | 0.0021 | 0.0846 | 0.0185 | 0.1319 | 0.0439 | 0.1403 | 0.0446 | 0.1617 | 0.0662 | 0.4487 | 0.8246 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0075 | 0.0012 | 0.0359 | 0.0131 | 0.0667 | 0.0284 | 0.0658 | 0.0201 | 0.0850 | 0.0339 | 0.7372 | 0.9033 | 0.0024 | 0.0066 | 0.0072 | 0.0197 | 0.0168 | 0.0623 | 0.0455 | 0.1049 | 0.1310 | 0.2164 | 0.1566 | 0.1934 | 0.1054 | 0.1213 | 0.1454 | 0.1016 | 0.3898 | 0.1738 | 0.0007 | 0.0013 | 0.0093 | 0.0251 | 0.0753 | 0.1245 | 0.0951 | 0.1176 | 0.5510 | 8 | 10 | 11 | 13 | 14 | 16 | 20 | 32 | 83 | 0.3458 | 2.93 | 2.365 | 0.7930 | 8689.1 | 4200000 | 2620000000 | 1850000000000 | 0.5811 | 0.1080 | 0.0885 | 0.0104 | 0.2543 | 0.0345 | 0.2812 | 0.1127 | 0.1438 | 0.1577 | 0.1011 | 0.2117 | 0.0616 | 0.1837 | 0.0442 | 0.1186 | 0.0221 | 0.0840 | 0.0032 | 0.0866 | 0.0012 | 0.0043 | 0.0039 | 0.0074 | 0.0075 | 0.0086 | 0.0365 | 0.0296 | 0.0821 | 0.0734 | 0.1147 | 0.0932 | 0.0825 | 0.0839 | 0.1222 | 0.1175 | 0.5495 | 0.5820 | 0.0016 | 0.0023 | 0.0031 | 0.0012 | 0.0047 | 0.0059 | 0.0350 | 0.0457 | 0.0957 | 0.1019 | 0.1479 | 0.1547 | 0.0883 | 0.0873 | 0.1181 | 0.1131 | 0.5055 | 0.4880 | 0.0009 | 0.0059 | 0.0054 | 0.0345 | 0.0917 | 0.1226 | 0.0903 | 0.1207 | 0.5279 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 591 | 329 | | 4059 | 4051 | 149.9 | 44.98 | 152.81 | 103.02 | 95 | 110 | 122 | 134 | 145 | 156 | 170 | 185 | 211 | 0.1824 | 739 | 0.920 | 69.64 | 26.25 | 1 | 0.0493 | 200 | 0.0013 | 36.19 | 6.869 | 0.2026 | 24493.5 | 4340000 | 829000000 | 169000000000 | 0.4381 | 0.2179 | 0.0010 | 0.0000 | 0.0020 | 0.0006 | 0.0237 | 0.0015 | 0.0622 | 0.0050 | 0.1475 | 0.0394 | 0.2153 | 0.0977 | 0.1769 | 0.0924 | 0.1511 | 0.1146 | 0.2203 | 0.6487 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0034 | 0.0008 | 0.0127 | 0.0016 | 0.0491 | 0.0255 | 0.1050 | 0.0516 | 0.0769 | 0.0408 | 0.0978 | 0.0574 | 0.6543 | 0.8222 | 0.0021 | 0.0071 | 0.0032 | 0.0095 | 0.0203 | 0.0309 | 0.0664 | 0.1164 | 0.1756 | 0.2019 | 0.1874 | 0.2233 | 0.1113 | 0.0879 | 0.1520 | 0.1164 | 0.2816 | 0.2067 | 0.0000 | 0.0011 | 0.0070 | 0.0316 | 0.1002 | 0.1522 | 0.0997 | 0.1442 | 0.4641 | 38 | 60 | 81 | 105 | 133 | 164 | 196 | 234 | 296 | 0.0029 | 26.57 | 6.397 | 0.3265 | 33960.4 | 9530000 | 3160000000 | 1200000000000 | 0.5229 | 0.1431 | 0.0171 | 0.0012 | 0.1148 | 0.0116 | 0.2369 | 0.0408 | 0.1685 | 0.0987 | 0.1709 | 0.1749 | 0.1258 | 0.2108 | 0.0733 | 0.1475 | 0.0635 | 0.1511 | 0.0293 | 0.1633 | 0.0000 | 0.0004 | 0.0037 | 0.0011 | 0.0064 | 0.0053 | 0.0320 | 0.0224 | 0.0859 | 0.0765 | 0.1293 | 0.1057 | 0.1028 | 0.0856 | 0.1325 | 0.1118 | 0.5073 | 0.5911 | 0.0037 | 0.0060 | 0.0073 | 0.0140 | 0.0190 | 0.0351 | 0.0467 | 0.0852 | 0.1402 | 0.1543 | 0.1958 | 0.1944 | 0.1242 | 0.1333 | 0.1570 | 0.1353 | 0.3061 | 0.2425 | 0.0017 | 0.0040 | 0.0090 | 0.0384 | 0.0942 | 0.1738 | 0.1196 | 0.1535 | 0.4058 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 591 | 322 | | 3805 | 8120 | 447.6 | 140.46 | 62.41 | 102.20 | 225 | 309 | 397 | 453 | 481 | 505 | 531 | 568 | 598 | 0.0792 | 643 | 1.179 | 95.75 | 35.78 | 2 | 0.0636 | 242 | 0.0012 | 24.22 | 7.023 | 0.2589 | 220069.0 | 114000000 | 61800000000 | 34400000000000 | 0.3868 | 0.2449 | 0.0017 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0114 | 0.0030 | 0.0542 | 0.0207 | 0.0787 | 0.0353 | 0.0685 | 0.0267 | 0.1038 | 0.0443 | 0.6805 | 0.8697 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0019 | 0.0183 | 0.0158 | 0.0254 | 0.0260 | 0.0183 | 0.0167 | 0.0268 | 0.0236 | 0.9097 | 0.9160 | 0.0009 | 0.0000 | 0.0037 | 0.0000 | 0.0083 | 0.0000 | 0.0111 | 0.0000 | 0.0426 | 0.0000 | 0.0546 | 0.0000 | 0.0592 | 0.0000 | 0.0823 | 0.0000 | 0.7373 | 1.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0047 | 0.0236 | 0.0356 | 0.0347 | 0.0592 | 0.8404 | 8 | 9 | 11 | 12 | 16 | 24 | 45 | 91 | 190 | 0.1789 | 5.12 | 3.242 | 0.6875 | 14337.8 | 5250000 | 2370000000 | 1220000000000 | 0.6067 | 0.0913 | 0.0581 | 0.0060 | 0.1183 | 0.0249 | 0.1618 | 0.0957 | 0.1390 | 0.1256 | 0.1784 | 0.1446 | 0.1515 | 0.1605 | 0.1224 | 0.1296 | 0.0456 | 0.0987 | 0.0249 | 0.2144 | 0.0017 | 0.0015 | 0.0035 | 0.0026 | 0.0035 | 0.0045 | 0.0138 | 0.0146 | 0.0558 | 0.0544 | 0.0878 | 0.0773 | 0.0636 | 0.0484 | 0.0930 | 0.0926 | 0.6775 | 0.7041 | 0.0005 | 0.0006 | 0.0005 | 0.0006 | 0.0033 | 0.0024 | 0.0169 | 0.0192 | 0.0754 | 0.0800 | 0.1038 | 0.1191 | 0.0644 | 0.0565 | 0.1032 | 0.1179 | 0.6319 | 0.6037 | 0.0010 | 0.0034 | 0.0039 | 0.0186 | 0.0658 | 0.0932 | 0.0677 | 0.0991 | 0.6472 |