High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 506 | 842 | | 4164 | 7027 | 174.9 | 56.54 | 178.00 | 147.56 | 112 | 130 | 142 | 152 | 163 | 178 | 195 | 217 | 248 | 0.0992 | 697 | 1.133 | 87.73 | 29.97 | 1 | 0.0531 | 221 | 0.0010 | 60.00 | 7.142 | 0.1752 | 33770.8 | 7210000 | 1700000000 | 440000000000 | 0.4464 | 0.2087 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0141 | 0.0006 | 0.0522 | 0.0044 | 0.1370 | 0.0397 | 0.1936 | 0.0823 | 0.1921 | 0.0887 | 0.1775 | 0.1264 | 0.2301 | 0.6580 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0116 | 0.0021 | 0.0475 | 0.0234 | 0.0857 | 0.0412 | 0.0834 | 0.0368 | 0.1113 | 0.0577 | 0.6565 | 0.8388 | 0.0031 | 0.0022 | 0.0021 | 0.0153 | 0.0073 | 0.0131 | 0.0636 | 0.1160 | 0.1366 | 0.1751 | 0.1783 | 0.2079 | 0.1220 | 0.1072 | 0.1689 | 0.1379 | 0.3180 | 0.2254 | 0.0011 | 0.0006 | 0.0034 | 0.0311 | 0.0911 | 0.1324 | 0.1046 | 0.1414 | 0.4943 | 27 | 50 | 74 | 106 | 140 | 178 | 225 | 292 | 389 | 0.0022 | 67.53 | 7.034 | 0.2591 | 53457.0 | 21400000 | 10400000000 | 5770000000000 | 0.4709 | 0.1839 | 0.0246 | 0.0021 | 0.1054 | 0.0050 | 0.2141 | 0.0504 | 0.1742 | 0.0881 | 0.1708 | 0.1448 | 0.1351 | 0.1725 | 0.0799 | 0.1469 | 0.0654 | 0.1452 | 0.0306 | 0.2451 | 0.0003 | 0.0007 | 0.0014 | 0.0000 | 0.0041 | 0.0026 | 0.0151 | 0.0086 | 0.0704 | 0.0509 | 0.1194 | 0.0961 | 0.0898 | 0.0692 | 0.1292 | 0.1056 | 0.5703 | 0.6664 | 0.0022 | 0.0022 | 0.0035 | 0.0049 | 0.0101 | 0.0121 | 0.0321 | 0.0351 | 0.0981 | 0.1185 | 0.1438 | 0.1580 | 0.1130 | 0.0971 | 0.1328 | 0.1377 | 0.4644 | 0.4344 | 0.0004 | 0.0028 | 0.0042 | 0.0276 | 0.0850 | 0.1324 | 0.0967 | 0.1328 | 0.5181 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 508 | 133 | | 5112 | 15953 | 596.9 | 122.93 | 209.99 | 332.25 | 447 | 490 | 521 | 552 | 585 | 617 | 653 | 698 | 767 | 0.0564 | 899 | 0.855 | 86.15 | 24.76 | 1 | 0.0428 | 219 | 0.0004 | 156.57 | 7.925 | 0.1053 | 371349.0 | 241000000 | 162000000000 | 113000000000000 | 0.4423 | 0.2051 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0187 | 0.0008 | 0.0672 | 0.0192 | 0.1466 | 0.0410 | 0.1398 | 0.0373 | 0.1694 | 0.0551 | 0.4551 | 0.8466 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0089 | 0.0004 | 0.0325 | 0.0132 | 0.0678 | 0.0246 | 0.0610 | 0.0151 | 0.0909 | 0.0305 | 0.7386 | 0.9162 | 0.0023 | 0.0043 | 0.0103 | 0.0043 | 0.0195 | 0.0468 | 0.0736 | 0.1319 | 0.1310 | 0.1872 | 0.2080 | 0.2468 | 0.1023 | 0.0936 | 0.1264 | 0.1106 | 0.3264 | 0.1745 | 0.0008 | 0.0025 | 0.0105 | 0.0257 | 0.0758 | 0.1281 | 0.1049 | 0.1184 | 0.5333 | 8 | 10 | 12 | 14 | 20 | 73 | 208 | 417 | 696 | 0.1770 | 37.47 | 4.561 | 0.5961 | 154477.0 | 156000000 | 189000000000 | 260000000000000 | 0.5567 | 0.1171 | 0.0435 | 0.0017 | 0.1317 | 0.0133 | 0.1719 | 0.0920 | 0.1462 | 0.1123 | 0.1551 | 0.1516 | 0.1272 | 0.1707 | 0.1071 | 0.1244 | 0.0737 | 0.1291 | 0.0435 | 0.2049 | 0.0000 | 0.0003 | 0.0002 | 0.0000 | 0.0013 | 0.0010 | 0.0089 | 0.0045 | 0.0312 | 0.0322 | 0.0618 | 0.0501 | 0.0532 | 0.0353 | 0.0709 | 0.0694 | 0.7724 | 0.8070 | 0.0005 | 0.0002 | 0.0000 | 0.0007 | 0.0023 | 0.0015 | 0.0087 | 0.0100 | 0.0449 | 0.0500 | 0.0795 | 0.0826 | 0.0525 | 0.0585 | 0.0887 | 0.0933 | 0.7230 | 0.7032 | 0.0008 | 0.0015 | 0.0023 | 0.0088 | 0.0390 | 0.0736 | 0.0524 | 0.0793 | 0.7423 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 508 | 386 | | 1856 | 6121 | 930.2 | 328.29 | 7.48 | 2.44 | 554 | 653 | 741 | 809 | 938 | 1045 | 1136 | 1227 | 1377 | 0.0853 | 522 | 1.026 | 43.86 | 14.14 | 1 | 0.0641 | 119 | 0.0008 | 115.28 | 7.271 | 0.1207 | 972996.0 | 1100000000 | 1310000000000 | 1.62E+15 | 0.4447 | 0.1728 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0173 | 0.0007 | 0.0317 | 0.0064 | 0.1400 | 0.0443 | 0.2107 | 0.1180 | 0.1486 | 0.0730 | 0.1962 | 0.1001 | 0.2554 | 0.6574 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0006 | 0.0093 | 0.0030 | 0.0388 | 0.0270 | 0.0705 | 0.0642 | 0.0496 | 0.0354 | 0.0659 | 0.0564 | 0.7651 | 0.8134 | 0.0034 | 0.0000 | 0.0000 | 0.0074 | 0.0000 | 0.0037 | 0.0201 | 0.0260 | 0.0586 | 0.1078 | 0.1273 | 0.1933 | 0.0771 | 0.0818 | 0.1039 | 0.0855 | 0.6097 | 0.4944 | 0.0000 | 0.0000 | 0.0000 | 0.0053 | 0.0427 | 0.0907 | 0.0491 | 0.0768 | 0.7353 | 5 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0178 | 7.81 | 4.411 | 0.3613 | 61.9 | 562.793 | 5603.58 | 60707.4 | 0.4721 | 0.1687 | 0.0133 | 0.0031 | 0.0511 | 0.0061 | 0.1011 | 0.0157 | 0.1867 | 0.0367 | 0.2357 | 0.0887 | 0.1933 | 0.1507 | 0.1532 | 0.2219 | 0.0544 | 0.2907 | 0.0113 | 0.1863 | 0.0006 | 0.0000 | 0.0046 | 0.0003 | 0.0191 | 0.0016 | 0.0469 | 0.0087 | 0.0879 | 0.0304 | 0.1387 | 0.0535 | 0.1808 | 0.0957 | 0.2333 | 0.2328 | 0.2882 | 0.5769 | 0.0957 | 0.1536 | 0.1428 | 0.1826 | 0.1400 | 0.1273 | 0.1328 | 0.0834 | 0.1079 | 0.0869 | 0.1063 | 0.0860 | 0.0847 | 0.0808 | 0.0841 | 0.0939 | 0.1057 | 0.1054 | 0.0056 | 0.0360 | 0.0685 | 0.1045 | 0.1391 | 0.1650 | 0.1550 | 0.1468 | 0.1796 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 817 | | 5202 | 13328 | 498.6 | 85.62 | 75.42 | 193.51 | 376 | 424 | 460 | 483 | 503 | 525 | 551 | 573 | 600 | 0.0606 | 808 | 0.924 | 121.38 | 32.28 | 1 | 0.0600 | 312 | 0.0016 | 14.59 | 6.726 | 0.2939 | 255905.0 | 135000000 | 72700000000 | 40000000000000 | 0.4179 | 0.2243 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0023 | 0.0002 | 0.0100 | 0.0010 | 0.0267 | 0.0117 | 0.0460 | 0.0271 | 0.0409 | 0.0125 | 0.0779 | 0.0230 | 0.7949 | 0.9246 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0041 | 0.0008 | 0.0129 | 0.0112 | 0.0226 | 0.0247 | 0.0142 | 0.0106 | 0.0293 | 0.0185 | 0.9158 | 0.9342 | 0.0074 | 0.0227 | 0.0185 | 0.0000 | 0.0444 | 0.0455 | 0.0628 | 0.0455 | 0.0795 | 0.1591 | 0.1109 | 0.1364 | 0.1146 | 0.1136 | 0.1109 | 0.1364 | 0.4510 | 0.3409 | 0.0022 | 0.0041 | 0.0081 | 0.0144 | 0.0276 | 0.0398 | 0.0446 | 0.0692 | 0.7901 | 8 | 10 | 11 | 12 | 14 | 17 | 27 | 59 | 186 | 0.2830 | 9.88 | 2.941 | 0.7317 | 43131.2 | 46900000 | 63500000000 | 95400000000000 | 0.3571 | 0.2342 | 0.0717 | 0.0047 | 0.2131 | 0.0292 | 0.2384 | 0.1318 | 0.1751 | 0.1111 | 0.1245 | 0.1770 | 0.0802 | 0.2062 | 0.0422 | 0.1234 | 0.0295 | 0.1036 | 0.0253 | 0.1130 | 0.0008 | 0.0003 | 0.0011 | 0.0036 | 0.0019 | 0.0062 | 0.0121 | 0.0147 | 0.0524 | 0.0421 | 0.0746 | 0.0718 | 0.0543 | 0.0492 | 0.0758 | 0.0744 | 0.7271 | 0.7378 | 0.0000 | 0.0005 | 0.0009 | 0.0010 | 0.0023 | 0.0025 | 0.0138 | 0.0125 | 0.0555 | 0.0609 | 0.0909 | 0.0973 | 0.0564 | 0.0579 | 0.0844 | 0.0868 | 0.6957 | 0.6806 | 0.0004 | 0.0017 | 0.0008 | 0.0138 | 0.0522 | 0.0823 | 0.0547 | 0.0852 | 0.7090 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 507 | | 7824 | 25276 | 555.9 | 107.56 | 87.69 | 105.95 | 423 | 462 | 493 | 518 | 545 | 575 | 609 | 649 | 706 | 0.0436 | 1102 | 1.007 | 126.85 | 35.51 | 1 | 0.0387 | 303 | 0.0006 | 69.54 | 7.651 | 0.1417 | 320582.0 | 192000000 | 118000000000 | 75400000000000 | 0.3901 | 0.2585 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0078 | 0.0004 | 0.0495 | 0.0148 | 0.1105 | 0.0312 | 0.1156 | 0.0262 | 0.1566 | 0.0356 | 0.5585 | 0.8919 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0235 | 0.0112 | 0.0491 | 0.0226 | 0.0541 | 0.0132 | 0.0699 | 0.0177 | 0.7998 | 0.9352 | 0.0031 | 0.0092 | 0.0086 | 0.0323 | 0.0163 | 0.0276 | 0.0467 | 0.1198 | 0.1346 | 0.1935 | 0.1486 | 0.2166 | 0.1121 | 0.1106 | 0.1307 | 0.1290 | 0.3992 | 0.1613 | 0.0008 | 0.0025 | 0.0044 | 0.0227 | 0.0729 | 0.1111 | 0.1003 | 0.1279 | 0.5575 | 8 | 10 | 12 | 19 | 41 | 74 | 111 | 159 | 230 | 0.0557 | 17.43 | 5.062 | 0.4981 | 18913.8 | 5940000 | 2360000000 | 1110000000000 | 0.5214 | 0.1569 | 0.0217 | 0.0010 | 0.1318 | 0.0082 | 0.2484 | 0.0573 | 0.1624 | 0.1006 | 0.1628 | 0.1863 | 0.1092 | 0.2103 | 0.0691 | 0.1325 | 0.0507 | 0.1178 | 0.0438 | 0.1859 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0013 | 0.0003 | 0.0090 | 0.0059 | 0.0434 | 0.0366 | 0.0864 | 0.0707 | 0.0600 | 0.0485 | 0.0853 | 0.0637 | 0.7144 | 0.7741 | 0.0004 | 0.0001 | 0.0010 | 0.0009 | 0.0023 | 0.0038 | 0.0153 | 0.0204 | 0.0611 | 0.0695 | 0.1126 | 0.1258 | 0.0774 | 0.0886 | 0.1029 | 0.1191 | 0.6271 | 0.5718 | 0.0000 | 0.0001 | 0.0020 | 0.0125 | 0.0561 | 0.0967 | 0.0714 | 0.0968 | 0.6644 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 512 | 618 | | 11255 | 20255 | 428.2 | 87.05 | 105.63 | 203.30 | 309 | 354 | 384 | 408 | 429 | 449 | 474 | 501 | 549 | 0.0544 | 1102 | 0.683 | 111.73 | 25.46 | 6 | 0.0275 | 310 | 0.0009 | 22.99 | 7.263 | 0.2438 | 190902.0 | 88200000 | 42000000000 | 20600000000000 | 0.4424 | 0.2031 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0026 | 0.0004 | 0.0084 | 0.0012 | 0.0280 | 0.0134 | 0.0584 | 0.0238 | 0.0474 | 0.0178 | 0.0713 | 0.0278 | 0.7829 | 0.9155 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0033 | 0.0008 | 0.0135 | 0.0104 | 0.0281 | 0.0209 | 0.0204 | 0.0124 | 0.0313 | 0.0184 | 0.9022 | 0.9370 | 0.0011 | 0.0000 | 0.0063 | 0.0000 | 0.0110 | 0.0000 | 0.0226 | 0.0000 | 0.0479 | 0.0000 | 0.0805 | 0.0000 | 0.0642 | 0.0000 | 0.0789 | 0.0000 | 0.6875 | 0.0000 | 0.0009 | 0.0019 | 0.0058 | 0.0140 | 0.0333 | 0.0539 | 0.0552 | 0.0744 | 0.7606 | 8 | 9 | 10 | 11 | 13 | 16 | 42 | 145 | 378 | 0.0720 | 5.26 | 3.153 | 0.4465 | 52486.1 | 36900000 | 30400000000 | 27900000000000 | 0.5667 | 0.1091 | 0.0648 | 0.0042 | 0.2221 | 0.0305 | 0.2455 | 0.1491 | 0.1821 | 0.1574 | 0.1255 | 0.1533 | 0.0690 | 0.1678 | 0.0331 | 0.1262 | 0.0317 | 0.0846 | 0.0262 | 0.1269 | 0.0004 | 0.0000 | 0.0006 | 0.0006 | 0.0010 | 0.0017 | 0.0112 | 0.0092 | 0.0467 | 0.0430 | 0.0696 | 0.0628 | 0.0485 | 0.0415 | 0.0752 | 0.0685 | 0.7467 | 0.7729 | 0.0005 | 0.0005 | 0.0007 | 0.0007 | 0.0016 | 0.0025 | 0.0113 | 0.0152 | 0.0565 | 0.0539 | 0.0774 | 0.0786 | 0.0493 | 0.0607 | 0.0870 | 0.0851 | 0.7156 | 0.7027 | 0.0007 | 0.0000 | 0.0020 | 0.0119 | 0.0543 | 0.0701 | 0.0508 | 0.0795 | 0.7308 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 516 | 891 | | 618 | 739 | 106.8 | 15.78 | 5.93 | 2.23 | 82 | 92 | 99 | 105 | 109 | 114 | 118 | 121 | 125 | 0.3234 | 239 | 1.055 | 76.24 | 24.70 | 1 | 0.3026 | 187 | 0.0261 | 2.24 | 3.925 | 0.5232 | 11645.2 | 1290000 | 146000000 | 16700000000 | 0.3863 | 0.2434 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0358 | 0.0405 | 0.0875 | 0.0631 | 0.1093 | 0.0275 | 0.1590 | 0.0469 | 0.5885 | 0.8220 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0188 | 0.0000 | 0.0282 | 0.0405 | 0.0545 | 0.0631 | 0.0545 | 0.0275 | 0.0395 | 0.0469 | 0.8045 | 0.8220 | 0.1034 | 0.0000 | 0.2414 | 0.0000 | 0.2414 | 0.0000 | 0.2414 | 0.0000 | 0.1034 | 0.0000 | 0.0690 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0277 | 0.0360 | 0.0305 | 0.0637 | 0.0665 | 0.1108 | 0.6648 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.5158 | 0.30 | 0.942 | 0.8384 | 40.2 | 298.797 | 2399.87 | 20613.1 | 0.4399 | 0.1643 | 0.0054 | 0.0000 | 0.0863 | 0.0054 | 0.1563 | 0.0342 | 0.3100 | 0.1081 | 0.2022 | 0.1856 | 0.1725 | 0.2270 | 0.0566 | 0.2378 | 0.0108 | 0.1640 | 0.0000 | 0.0378 | 0.0000 | 0.0000 | 0.0186 | 0.0016 | 0.0557 | 0.0188 | 0.1002 | 0.0518 | 0.1670 | 0.1256 | 0.2041 | 0.1680 | 0.2059 | 0.2135 | 0.1837 | 0.2370 | 0.0649 | 0.1837 | 0.1845 | 0.4878 | 0.2917 | 0.2195 | 0.2440 | 0.2195 | 0.2024 | 0.0732 | 0.0476 | 0.0000 | 0.0298 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0213 | 0.0520 | 0.1348 | 0.1442 | 0.1891 | 0.1915 | 0.1277 | 0.1040 | 0.0355 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 517 | 209 | | 10942 | 35449 | 447.3 | 110.82 | 142.08 | 205.96 | 312 | 350 | 381 | 410 | 439 | 469 | 501 | 538 | 598 | 0.0363 | 1286 | 0.903 | 94.01 | 21.02 | 3 | 0.0206 | 225 | 0.0006 | 67.31 | 7.714 | 0.1503 | 212393.0 | 107000000 | 56200000000 | 31100000000000 | 0.4346 | 0.2214 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0049 | 0.0003 | 0.0220 | 0.0020 | 0.0807 | 0.0222 | 0.1586 | 0.0494 | 0.1521 | 0.0568 | 0.1699 | 0.0831 | 0.4104 | 0.7861 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0011 | 0.0001 | 0.0069 | 0.0010 | 0.0331 | 0.0142 | 0.0664 | 0.0263 | 0.0584 | 0.0248 | 0.0766 | 0.0387 | 0.7570 | 0.8948 | 0.0022 | 0.0069 | 0.0081 | 0.0139 | 0.0103 | 0.0416 | 0.0550 | 0.1150 | 0.1279 | 0.1967 | 0.1699 | 0.1884 | 0.1225 | 0.1177 | 0.1516 | 0.1399 | 0.3524 | 0.1801 | 0.0008 | 0.0008 | 0.0065 | 0.0223 | 0.0687 | 0.1106 | 0.0929 | 0.1244 | 0.5730 | 7 | 10 | 12 | 15 | 24 | 71 | 163 | 276 | 443 | 0.1042 | 31.77 | 4.906 | 0.5483 | 62607.4 | 38100000 | 28100000000 | 23900000000000 | 0.4712 | 0.1726 | 0.0362 | 0.0022 | 0.1614 | 0.0112 | 0.2304 | 0.0744 | 0.1585 | 0.1487 | 0.1473 | 0.1922 | 0.1121 | 0.1786 | 0.0662 | 0.1198 | 0.0498 | 0.1135 | 0.0382 | 0.1594 | 0.0002 | 0.0001 | 0.0002 | 0.0002 | 0.0007 | 0.0005 | 0.0067 | 0.0061 | 0.0345 | 0.0311 | 0.0658 | 0.0530 | 0.0462 | 0.0389 | 0.0718 | 0.0600 | 0.7738 | 0.8102 | 0.0000 | 0.0005 | 0.0006 | 0.0007 | 0.0010 | 0.0021 | 0.0102 | 0.0107 | 0.0492 | 0.0560 | 0.0855 | 0.0946 | 0.0637 | 0.0738 | 0.0966 | 0.1019 | 0.6933 | 0.6595 | 0.0002 | 0.0003 | 0.0018 | 0.0074 | 0.0431 | 0.0740 | 0.0560 | 0.0876 | 0.7297 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 518 | 503 | | 15648 | 56021 | 320.9 | 59.50 | 142.33 | 181.99 | 244 | 279 | 299 | 315 | 329 | 341 | 354 | 368 | 389 | 0.0239 | 1341 | 0.987 | 126.85 | 36.01 | 1 | 0.0202 | 316 | 0.0015 | 21.65 | 6.855 | 0.2488 | 106538.0 | 36300000 | 12600000000 | 4480000000000 | 0.4413 | 0.2040 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0079 | 0.0003 | 0.0295 | 0.0078 | 0.0562 | 0.0157 | 0.0615 | 0.0104 | 0.0915 | 0.0162 | 0.7503 | 0.9496 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0023 | 0.0003 | 0.0109 | 0.0075 | 0.0242 | 0.0143 | 0.0210 | 0.0081 | 0.0316 | 0.0119 | 0.9098 | 0.9580 | 0.0090 | 0.0536 | 0.0157 | 0.0179 | 0.0336 | 0.1429 | 0.0745 | 0.2143 | 0.1272 | 0.1429 | 0.1557 | 0.1607 | 0.1429 | 0.1071 | 0.1597 | 0.0357 | 0.2818 | 0.1250 | 0.0008 | 0.0025 | 0.0050 | 0.0158 | 0.0410 | 0.0684 | 0.0815 | 0.0977 | 0.6873 | 8 | 10 | 12 | 18 | 51 | 108 | 178 | 269 | 424 | 0.1076 | 16.66 | 4.969 | 0.5393 | 53375.8 | 26600000 | 15300000000 | 9680000000000 | 0.3694 | 0.2725 | 0.0166 | 0.0013 | 0.1012 | 0.0060 | 0.2168 | 0.0361 | 0.1910 | 0.0912 | 0.1770 | 0.1724 | 0.1403 | 0.2115 | 0.0824 | 0.1547 | 0.0457 | 0.1475 | 0.0291 | 0.1792 | 0.0006 | 0.0002 | 0.0006 | 0.0006 | 0.0027 | 0.0015 | 0.0085 | 0.0065 | 0.0354 | 0.0299 | 0.0682 | 0.0565 | 0.0555 | 0.0459 | 0.0719 | 0.0641 | 0.7567 | 0.7947 | 0.0005 | 0.0005 | 0.0022 | 0.0022 | 0.0040 | 0.0048 | 0.0126 | 0.0154 | 0.0463 | 0.0551 | 0.0837 | 0.0934 | 0.0695 | 0.0743 | 0.0862 | 0.0911 | 0.6950 | 0.6633 | 0.0005 | 0.0017 | 0.0041 | 0.0114 | 0.0416 | 0.0737 | 0.0613 | 0.0797 | 0.7260 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 524 | 141 | | 4317 | 6246 | 463.8 | 114.50 | 71.69 | 106.41 | 339 | 369 | 392 | 415 | 440 | 467 | 500 | 549 | 629 | 0.1005 | 628 | 1.211 | 95.02 | 37.48 | 1 | 0.0563 | 243 | 0.0011 | 40.02 | 7.058 | 0.1884 | 228193.0 | 119000000 | 66600000000 | 39500000000000 | 0.3905 | 0.2504 | 0.0000 | 0.0000 | 0.0012 | 0.0005 | 0.0054 | 0.0005 | 0.0173 | 0.0033 | 0.0695 | 0.0228 | 0.1245 | 0.0415 | 0.1318 | 0.0400 | 0.1690 | 0.0488 | 0.4814 | 0.8426 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0000 | 0.0076 | 0.0009 | 0.0334 | 0.0140 | 0.0577 | 0.0244 | 0.0633 | 0.0147 | 0.0882 | 0.0216 | 0.7466 | 0.9244 | 0.0037 | 0.0000 | 0.0049 | 0.0057 | 0.0099 | 0.0345 | 0.0469 | 0.0690 | 0.0877 | 0.1293 | 0.1395 | 0.1264 | 0.1025 | 0.1264 | 0.1173 | 0.1494 | 0.4877 | 0.3592 | 0.0006 | 0.0051 | 0.0130 | 0.0395 | 0.0745 | 0.1072 | 0.0874 | 0.0987 | 0.5742 | 7 | 10 | 12 | 15 | 21 | 31 | 56 | 127 | 227 | 0.0902 | 12.13 | 4.224 | 0.6055 | 16459.4 | 5640000 | 2380000000 | 1160000000000 | 0.4828 | 0.1513 | 0.0532 | 0.0047 | 0.1894 | 0.0235 | 0.2990 | 0.0691 | 0.2359 | 0.1821 | 0.1196 | 0.2323 | 0.0698 | 0.2276 | 0.0266 | 0.1366 | 0.0000 | 0.0754 | 0.0066 | 0.0487 | 0.0000 | 0.0014 | 0.0000 | 0.0014 | 0.0022 | 0.0039 | 0.0129 | 0.0082 | 0.0533 | 0.0488 | 0.0787 | 0.0768 | 0.0566 | 0.0497 | 0.0981 | 0.0888 | 0.6983 | 0.7209 | 0.0000 | 0.0000 | 0.0013 | 0.0021 | 0.0058 | 0.0077 | 0.0154 | 0.0112 | 0.0624 | 0.0732 | 0.0977 | 0.0962 | 0.0585 | 0.0635 | 0.1145 | 0.1123 | 0.6444 | 0.6339 | 0.0000 | 0.0018 | 0.0035 | 0.0183 | 0.0589 | 0.0796 | 0.0654 | 0.0961 | 0.6765 | ||
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 524 | 311 | | 7833 | 16316 | 159.4 | 129.05 | 84.65 | 174.06 | 65 | 76 | 86 | 97 | 114 | 131 | 150 | 185 | 382 | 0.0834 | 1360 | 1.188 | 60.96 | 23.71 | 5 | 0.0200 | 157 | 0.0057 | 7.18 | 5.903 | 0.4831 | 42052.4 | 16100000 | 7440000000 | 3750000000000 | 0.4134 | 0.2024 | 0.0022 | 0.0044 | 0.0039 | 0.0032 | 0.0061 | 0.0041 | 0.0335 | 0.0116 | 0.0754 | 0.0367 | 0.0972 | 0.0576 | 0.0972 | 0.0547 | 0.1056 | 0.0789 | 0.5788 | 0.7488 | 0.0012 | 0.0031 | 0.0021 | 0.0023 | 0.0027 | 0.0029 | 0.0140 | 0.0079 | 0.0273 | 0.0211 | 0.0334 | 0.0280 | 0.0404 | 0.0320 | 0.0507 | 0.0445 | 0.8282 | 0.8580 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0033 | 0.0000 | 0.0086 | 0.0022 | 0.0213 | 0.0230 | 0.0452 | 0.0445 | 0.0219 | 0.0208 | 0.0359 | 0.0408 | 0.8625 | 0.8687 | 0.0005 | 0.0039 | 0.0043 | 0.0096 | 0.0294 | 0.0487 | 0.0352 | 0.0545 | 0.8140 | 8 | 10 | 12 | 15 | 18 | 24 | 39 | 87 | 242 | 0.1992 | 8.64 | 2.988 | 0.7068 | 37461.6 | 26400000 | 22100000000 | 20600000000000 | 0.5330 | 0.1352 | 0.0090 | 0.0029 | 0.0336 | 0.0070 | 0.0493 | 0.0187 | 0.1087 | 0.0531 | 0.1659 | 0.0904 | 0.1839 | 0.1376 | 0.1390 | 0.1405 | 0.1312 | 0.1359 | 0.1794 | 0.4140 | 0.0005 | 0.0009 | 0.0029 | 0.0023 | 0.0029 | 0.0042 | 0.0098 | 0.0168 | 0.0383 | 0.0349 | 0.0554 | 0.0519 | 0.0449 | 0.0496 | 0.0660 | 0.0575 | 0.7794 | 0.7817 | 0.0021 | 0.0004 | 0.0017 | 0.0035 | 0.0045 | 0.0047 | 0.0141 | 0.0116 | 0.0497 | 0.0520 | 0.0783 | 0.0849 | 0.0583 | 0.0621 | 0.0852 | 0.0791 | 0.7060 | 0.7017 | 0.0009 | 0.0033 | 0.0045 | 0.0117 | 0.0415 | 0.0667 | 0.0505 | 0.0739 | 0.7471 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 525 | 784 | | 306 | 3162 | 64.0 | 11.66 | 117.65 | 178.73 | 49 | 52 | 58 | 61 | 64 | 67 | 70 | 74 | 79 | 0.1395 | 441 | 1.153 | 68.73 | 23.77 | 1 | 0.5556 | 170 | 0.0077 | 10.17 | 5.047 | 0.3110 | 4226.0 | 287862 | 20200000 | 1450000000 | 0.4562 | 0.1761 | 0.0000 | 0.0000 | 0.0147 | 0.0033 | 0.0196 | 0.0000 | 0.0686 | 0.0133 | 0.1520 | 0.0365 | 0.1765 | 0.1794 | 0.1520 | 0.0332 | 0.1912 | 0.1296 | 0.2255 | 0.6047 | 0.0000 | 0.0000 | 0.0118 | 0.0033 | 0.0039 | 0.0000 | 0.0433 | 0.0131 | 0.0630 | 0.0359 | 0.1299 | 0.1634 | 0.0591 | 0.0327 | 0.1378 | 0.0882 | 0.5512 | 0.6634 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0800 | 0.0000 | 0.0600 | 0.8000 | 0.2200 | 0.2000 | 0.2000 | 0.0000 | 0.1400 | 0.0000 | 0.1400 | 0.0000 | 0.1200 | 0.0000 | 0.0062 | 0.0124 | 0.0248 | 0.0559 | 0.1242 | 0.0994 | 0.1242 | 0.1180 | 0.4348 | 11 | 12 | 13 | 15 | 18 | 44 | 106 | 220 | 400 | 0.1851 | 37.34 | 4.002 | 0.6018 | 45776.0 | 25200000 | 16900000000 | 13200000000000 | 0.6720 | 0.0567 | 0.1282 | 0.0081 | 0.1949 | 0.0782 | 0.2513 | 0.1240 | 0.1179 | 0.1563 | 0.1128 | 0.1725 | 0.0667 | 0.1590 | 0.0359 | 0.0755 | 0.0359 | 0.0916 | 0.0564 | 0.1348 | 0.0010 | 0.0000 | 0.0010 | 0.0009 | 0.0040 | 0.0027 | 0.0210 | 0.0153 | 0.0791 | 0.0694 | 0.1351 | 0.1127 | 0.1011 | 0.0902 | 0.1592 | 0.1461 | 0.4985 | 0.5627 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0012 | 0.0054 | 0.0348 | 0.0312 | 0.1057 | 0.1098 | 0.1480 | 0.1707 | 0.1294 | 0.1328 | 0.1654 | 0.1667 | 0.4142 | 0.3821 | 0.0011 | 0.0000 | 0.0033 | 0.0255 | 0.0909 | 0.1408 | 0.1098 | 0.1663 | 0.4623 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 526 | 612 | | 4592 | 11096 | 714.2 | 99.82 | 91.74 | 166.81 | 589 | 634 | 669 | 693 | 712 | 732 | 756 | 790 | 865 | 0.0617 | 685 | 1.192 | 82.49 | 32.31 | 1 | 0.0464 | 213 | 0.0012 | 39.16 | 7.036 | 0.2240 | 520098.0 | 386000000 | 291000000000 | 223000000000000 | 0.3926 | 0.2577 | 0.0013 | 0.0000 | 0.0016 | 0.0000 | 0.0024 | 0.0000 | 0.0078 | 0.0000 | 0.0202 | 0.0126 | 0.0427 | 0.0244 | 0.0333 | 0.0109 | 0.0462 | 0.0196 | 0.8444 | 0.9324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0000 | 0.0120 | 0.0126 | 0.0271 | 0.0244 | 0.0165 | 0.0109 | 0.0268 | 0.0196 | 0.9153 | 0.9324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0133 | 0.0000 | 0.0285 | 0.0000 | 0.0645 | 0.0000 | 0.1082 | 0.0000 | 0.1176 | 0.0000 | 0.1442 | 0.0000 | 0.5237 | 0.0000 | 0.0022 | 0.0027 | 0.0111 | 0.0200 | 0.0408 | 0.0616 | 0.0585 | 0.0789 | 0.7242 | 7 | 9 | 10 | 13 | 19 | 35 | 59 | 122 | 282 | 0.1396 | 15.62 | 3.866 | 0.6295 | 36238.5 | 22600000 | 17000000000 | 14400000000000 | 0.4303 | 0.1803 | 0.0541 | 0.0062 | 0.1723 | 0.0346 | 0.2804 | 0.0892 | 0.1486 | 0.1277 | 0.1216 | 0.1600 | 0.0912 | 0.1738 | 0.0456 | 0.1138 | 0.0372 | 0.1200 | 0.0490 | 0.1746 | 0.0007 | 0.0006 | 0.0014 | 0.0026 | 0.0061 | 0.0038 | 0.0208 | 0.0191 | 0.0546 | 0.0430 | 0.0869 | 0.0774 | 0.0440 | 0.0543 | 0.0617 | 0.0676 | 0.7238 | 0.7317 | 0.0009 | 0.0009 | 0.0021 | 0.0023 | 0.0081 | 0.0069 | 0.0214 | 0.0236 | 0.0585 | 0.0573 | 0.0880 | 0.0906 | 0.0440 | 0.0495 | 0.0679 | 0.0703 | 0.7091 | 0.6986 | 0.0008 | 0.0015 | 0.0073 | 0.0191 | 0.0546 | 0.0863 | 0.0454 | 0.0569 | 0.7281 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 527 | 515 | | 5715 | 12689 | 251.9 | 56.62 | 150.62 | 209.22 | 183 | 202 | 219 | 233 | 247 | 260 | 276 | 297 | 331 | 0.0632 | 802 | 1.048 | 109.64 | 33.14 | 1 | 0.0469 | 268 | 0.0008 | 63.76 | 7.408 | 0.1534 | 66641.6 | 18500000 | 5370000000 | 1630000000000 | 0.4360 | 0.2148 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0025 | 0.0002 | 0.0187 | 0.0025 | 0.0696 | 0.0238 | 0.1504 | 0.0429 | 0.1390 | 0.0489 | 0.1636 | 0.0736 | 0.4555 | 0.8082 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0002 | 0.0059 | 0.0005 | 0.0317 | 0.0144 | 0.0696 | 0.0231 | 0.0635 | 0.0224 | 0.0854 | 0.0339 | 0.7433 | 0.9055 | 0.0039 | 0.0090 | 0.0117 | 0.0180 | 0.0098 | 0.0689 | 0.0615 | 0.1377 | 0.1200 | 0.1707 | 0.1698 | 0.2006 | 0.1307 | 0.1257 | 0.1512 | 0.1168 | 0.3415 | 0.1527 | 0.0004 | 0.0038 | 0.0072 | 0.0249 | 0.0879 | 0.1271 | 0.1094 | 0.1309 | 0.5085 | 13 | 16 | 20 | 28 | 50 | 82 | 128 | 280 | 472 | 0.0397 | 26.37 | 5.194 | 0.5314 | 66455.3 | 40900000 | 29300000000 | 23200000000000 | 0.6051 | 0.0829 | 0.0898 | 0.0028 | 0.1918 | 0.0158 | 0.2116 | 0.1088 | 0.1233 | 0.1172 | 0.1218 | 0.1714 | 0.1233 | 0.1426 | 0.0502 | 0.0857 | 0.0548 | 0.1144 | 0.0335 | 0.2413 | 0.0015 | 0.0000 | 0.0020 | 0.0002 | 0.0046 | 0.0019 | 0.0130 | 0.0093 | 0.0490 | 0.0542 | 0.0785 | 0.0762 | 0.0554 | 0.0529 | 0.0773 | 0.0855 | 0.7187 | 0.7197 | 0.0003 | 0.0000 | 0.0003 | 0.0007 | 0.0015 | 0.0007 | 0.0079 | 0.0102 | 0.0580 | 0.0565 | 0.0827 | 0.0953 | 0.0638 | 0.0723 | 0.0958 | 0.1029 | 0.6898 | 0.6614 | 0.0006 | 0.0003 | 0.0017 | 0.0073 | 0.0525 | 0.0797 | 0.0581 | 0.0850 | 0.7149 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 532 | 259 | | 3712 | 5457 | 168.2 | 45.22 | 152.55 | 98.18 | 118 | 130 | 141 | 151 | 161 | 171 | 183 | 199 | 228 | 0.1063 | 580 | 0.874 | 81.88 | 22.63 | 1 | 0.0568 | 211 | 0.0014 | 50.43 | 6.887 | 0.1876 | 30320.2 | 5890000 | 1230000000 | 278000000000 | 0.4069 | 0.2403 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0062 | 0.0000 | 0.0317 | 0.0030 | 0.1075 | 0.0290 | 0.1833 | 0.0635 | 0.1611 | 0.0635 | 0.1701 | 0.0982 | 0.3382 | 0.7428 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0000 | 0.0092 | 0.0008 | 0.0427 | 0.0178 | 0.0828 | 0.0324 | 0.0732 | 0.0250 | 0.0970 | 0.0453 | 0.6925 | 0.8788 | 0.0043 | 0.0098 | 0.0085 | 0.0131 | 0.0199 | 0.0359 | 0.0641 | 0.1242 | 0.1709 | 0.1797 | 0.1966 | 0.2222 | 0.1040 | 0.1307 | 0.1496 | 0.1242 | 0.2821 | 0.1601 | 0.0006 | 0.0044 | 0.0087 | 0.0355 | 0.1060 | 0.1390 | 0.1228 | 0.1465 | 0.4364 | 47 | 67 | 88 | 108 | 132 | 156 | 187 | 227 | 288 | 0.0026 | 30.72 | 6.456 | 0.2975 | 32908.8 | 9090000 | 3020000000 | 1160000000000 | 0.5362 | 0.1215 | 0.0115 | 0.0020 | 0.0516 | 0.0061 | 0.1491 | 0.0235 | 0.1589 | 0.0465 | 0.1851 | 0.1266 | 0.1720 | 0.1828 | 0.1261 | 0.1517 | 0.0827 | 0.1485 | 0.0631 | 0.3123 | 0.0007 | 0.0008 | 0.0017 | 0.0011 | 0.0079 | 0.0030 | 0.0171 | 0.0129 | 0.0690 | 0.0487 | 0.1097 | 0.0810 | 0.0861 | 0.0732 | 0.1168 | 0.1001 | 0.5910 | 0.6792 | 0.0012 | 0.0008 | 0.0059 | 0.0096 | 0.0152 | 0.0241 | 0.0463 | 0.0643 | 0.1032 | 0.1230 | 0.1641 | 0.1873 | 0.1208 | 0.1270 | 0.1319 | 0.1367 | 0.4115 | 0.3272 | 0.0018 | 0.0009 | 0.0066 | 0.0331 | 0.0888 | 0.1391 | 0.1069 | 0.1343 | 0.4885 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 532 | 476 | | 5219 | 14862 | 435.3 | 124.40 | 337.57 | 481.74 | 232 | 330 | 406 | 440 | 463 | 485 | 504 | 529 | 568 | 0.0615 | 914 | 1.000 | 128.22 | 48.33 | 2 | 0.0674 | 352 | 0.0008 | 45.97 | 7.490 | 0.1610 | 204925.0 | 101000000 | 51900000000 | 27400000000000 | 0.3800 | 0.2460 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0028 | 0.0002 | 0.0186 | 0.0019 | 0.0502 | 0.0190 | 0.0908 | 0.0389 | 0.0881 | 0.0283 | 0.1132 | 0.0482 | 0.6350 | 0.8635 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0009 | 0.0137 | 0.0123 | 0.0238 | 0.0237 | 0.0137 | 0.0121 | 0.0218 | 0.0185 | 0.9249 | 0.9326 | 0.0043 | 0.0084 | 0.0077 | 0.0422 | 0.0163 | 0.0253 | 0.0463 | 0.0633 | 0.0891 | 0.1266 | 0.1380 | 0.2194 | 0.1157 | 0.1181 | 0.1302 | 0.1646 | 0.4524 | 0.2321 | 0.0000 | 0.0000 | 0.0015 | 0.0080 | 0.0250 | 0.0367 | 0.0598 | 0.0712 | 0.7979 | 11 | 14 | 20 | 38 | 87 | 185 | 377 | 650 | 1059 | 0.0509 | 117.91 | 5.882 | 0.4621 | 346014.0 | 476000000 | 763000000000 | 1.34E+15 | 0.4474 | 0.1983 | 0.0233 | 0.0011 | 0.1329 | 0.0091 | 0.3034 | 0.0582 | 0.1982 | 0.0988 | 0.1639 | 0.2045 | 0.0941 | 0.2654 | 0.0532 | 0.1442 | 0.0199 | 0.1116 | 0.0111 | 0.1073 | 0.0000 | 0.0003 | 0.0002 | 0.0009 | 0.0017 | 0.0007 | 0.0048 | 0.0049 | 0.0457 | 0.0381 | 0.0817 | 0.0764 | 0.0489 | 0.0433 | 0.0740 | 0.0659 | 0.7430 | 0.7695 | 0.0002 | 0.0003 | 0.0007 | 0.0008 | 0.0019 | 0.0033 | 0.0107 | 0.0121 | 0.0534 | 0.0598 | 0.0963 | 0.1052 | 0.0590 | 0.0678 | 0.0919 | 0.0965 | 0.6858 | 0.6543 | 0.0000 | 0.0008 | 0.0017 | 0.0079 | 0.0480 | 0.0926 | 0.0499 | 0.0801 | 0.7189 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 533 | 682 | | 7313 | 29998 | 383.9 | 96.67 | 156.93 | 277.72 | 269 | 302 | 327 | 350 | 372 | 397 | 429 | 467 | 513 | 0.0399 | 1198 | 1.208 | 132.80 | 56.82 | 1 | 0.0483 | 353 | 0.0008 | 42.70 | 7.362 | 0.1796 | 156719.0 | 67700000 | 30900000000 | 14700000000000 | 0.4294 | 0.2186 | 0.0000 | 0.0002 | 0.0019 | 0.0000 | 0.0056 | 0.0006 | 0.0223 | 0.0032 | 0.0776 | 0.0240 | 0.1395 | 0.0531 | 0.1380 | 0.0451 | 0.1584 | 0.0649 | 0.4567 | 0.8089 | 0.0000 | 0.0001 | 0.0011 | 0.0000 | 0.0023 | 0.0003 | 0.0074 | 0.0016 | 0.0342 | 0.0155 | 0.0598 | 0.0314 | 0.0600 | 0.0208 | 0.0798 | 0.0327 | 0.7556 | 0.8977 | 0.0032 | 0.0056 | 0.0051 | 0.0093 | 0.0051 | 0.0075 | 0.0329 | 0.0746 | 0.0981 | 0.1362 | 0.1253 | 0.2034 | 0.1101 | 0.1063 | 0.1380 | 0.1716 | 0.4823 | 0.2854 | 0.0003 | 0.0015 | 0.0075 | 0.0301 | 0.0733 | 0.1004 | 0.0869 | 0.1025 | 0.5975 | 8 | 9 | 11 | 12 | 15 | 25 | 92 | 285 | 569 | 0.2355 | 33.94 | 3.958 | 0.6313 | 101753.0 | 91200000 | 98600000000 | 124000000000000 | 0.4779 | 0.1557 | 0.1073 | 0.0081 | 0.3320 | 0.0585 | 0.3330 | 0.2590 | 0.1394 | 0.2001 | 0.0471 | 0.2020 | 0.0301 | 0.1388 | 0.0090 | 0.0741 | 0.0020 | 0.0371 | 0.0000 | 0.0223 | 0.0002 | 0.0004 | 0.0006 | 0.0011 | 0.0008 | 0.0010 | 0.0076 | 0.0093 | 0.0425 | 0.0390 | 0.0726 | 0.0654 | 0.0486 | 0.0443 | 0.0803 | 0.0682 | 0.7467 | 0.7711 | 0.0001 | 0.0001 | 0.0004 | 0.0000 | 0.0019 | 0.0013 | 0.0107 | 0.0116 | 0.0477 | 0.0518 | 0.0894 | 0.1012 | 0.0658 | 0.0667 | 0.0972 | 0.1078 | 0.6868 | 0.6595 | 0.0000 | 0.0005 | 0.0009 | 0.0099 | 0.0457 | 0.0788 | 0.0566 | 0.0902 | 0.7173 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 534 | 923 | | 4850 | 8622 | 162.0 | 44.63 | 180.98 | 189.76 | 115 | 127 | 136 | 144 | 153 | 163 | 176 | 194 | 220 | 0.0923 | 796 | 1.107 | 100.01 | 36.69 | 1 | 0.0542 | 263 | 0.0016 | 35.56 | 6.803 | 0.2042 | 28220.0 | 5320000 | 1090000000 | 244000000000 | 0.4589 | 0.1995 | 0.0007 | 0.0000 | 0.0029 | 0.0005 | 0.0119 | 0.0016 | 0.0353 | 0.0018 | 0.0965 | 0.0224 | 0.1780 | 0.0576 | 0.1567 | 0.0576 | 0.1780 | 0.0908 | 0.3401 | 0.7676 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0024 | 0.0000 | 0.0113 | 0.0004 | 0.0464 | 0.0146 | 0.0848 | 0.0310 | 0.0754 | 0.0240 | 0.1095 | 0.0437 | 0.6690 | 0.8863 | 0.0021 | 0.0124 | 0.0095 | 0.0173 | 0.0148 | 0.0173 | 0.0674 | 0.0990 | 0.1349 | 0.1708 | 0.1802 | 0.1931 | 0.1117 | 0.0990 | 0.1454 | 0.1411 | 0.3340 | 0.2500 | 0.0025 | 0.0020 | 0.0129 | 0.0373 | 0.0821 | 0.1318 | 0.1035 | 0.1274 | 0.5005 | 14 | 24 | 41 | 71 | 110 | 159 | 230 | 325 | 469 | 0.0065 | 92.57 | 6.832 | 0.2972 | 68756.7 | 35000000 | 20900000000 | 13800000000000 | 0.4654 | 0.1787 | 0.0372 | 0.0015 | 0.1157 | 0.0126 | 0.2314 | 0.0576 | 0.2038 | 0.0919 | 0.1826 | 0.1859 | 0.1210 | 0.2273 | 0.0605 | 0.1485 | 0.0297 | 0.1348 | 0.0180 | 0.1399 | 0.0011 | 0.0005 | 0.0019 | 0.0018 | 0.0057 | 0.0016 | 0.0164 | 0.0127 | 0.0655 | 0.0540 | 0.0911 | 0.0881 | 0.0668 | 0.0623 | 0.0898 | 0.0865 | 0.6617 | 0.6924 | 0.0018 | 0.0000 | 0.0015 | 0.0081 | 0.0066 | 0.0098 | 0.0239 | 0.0242 | 0.0668 | 0.0752 | 0.1146 | 0.1134 | 0.0856 | 0.0935 | 0.1050 | 0.1143 | 0.5942 | 0.5616 | 0.0003 | 0.0028 | 0.0070 | 0.0215 | 0.0579 | 0.0958 | 0.0730 | 0.1078 | 0.6339 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 536 | 592 | | 11784 | 41678 | 115.6 | 34.59 | 207.83 | 214.61 | 75 | 86 | 94 | 103 | 111 | 120 | 130 | 144 | 163 | 0.0416 | 1732 | 0.727 | 154.55 | 39.40 | 3 | 0.0386 | 455 | 0.0021 | 19.63 | 6.518 | 0.2766 | 14550.8 | 1990000 | 293000000 | 46400000000 | 0.4899 | 0.1699 | 0.0021 | 0.0004 | 0.0048 | 0.0007 | 0.0141 | 0.0032 | 0.0416 | 0.0077 | 0.1062 | 0.0329 | 0.1621 | 0.0738 | 0.1591 | 0.0708 | 0.1647 | 0.0991 | 0.3453 | 0.7113 | 0.0007 | 0.0001 | 0.0018 | 0.0005 | 0.0040 | 0.0013 | 0.0122 | 0.0039 | 0.0406 | 0.0176 | 0.0687 | 0.0392 | 0.0628 | 0.0280 | 0.0796 | 0.0464 | 0.7295 | 0.8631 | 0.0022 | 0.0025 | 0.0041 | 0.0115 | 0.0137 | 0.0329 | 0.0504 | 0.0873 | 0.1067 | 0.1853 | 0.1530 | 0.1919 | 0.1278 | 0.1227 | 0.1467 | 0.1524 | 0.3956 | 0.2133 | 0.0013 | 0.0036 | 0.0085 | 0.0266 | 0.0690 | 0.1142 | 0.0929 | 0.1140 | 0.5699 | 15 | 20 | 37 | 80 | 139 | 203 | 278 | 375 | 515 | 0.0215 | 74.38 | 6.685 | 0.3397 | 89248.9 | 51000000 | 34800000000 | 27200000000000 | 0.4252 | 0.2362 | 0.0235 | 0.0012 | 0.1173 | 0.0073 | 0.2179 | 0.0568 | 0.1485 | 0.1081 | 0.1623 | 0.1648 | 0.1467 | 0.2023 | 0.0826 | 0.1340 | 0.0615 | 0.1331 | 0.0396 | 0.1923 | 0.0003 | 0.0001 | 0.0006 | 0.0004 | 0.0028 | 0.0018 | 0.0089 | 0.0066 | 0.0493 | 0.0407 | 0.0985 | 0.0784 | 0.0722 | 0.0592 | 0.0927 | 0.0831 | 0.6748 | 0.7298 | 0.0013 | 0.0008 | 0.0022 | 0.0025 | 0.0046 | 0.0081 | 0.0169 | 0.0211 | 0.0664 | 0.0802 | 0.1232 | 0.1307 | 0.0875 | 0.0958 | 0.1112 | 0.1158 | 0.5867 | 0.5449 | 0.0005 | 0.0023 | 0.0051 | 0.0144 | 0.0596 | 0.1114 | 0.0778 | 0.1061 | 0.6229 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 537 | 652 | | 760 | 4733 | 183.3 | 48.14 | 141.14 | 250.71 | 130 | 142 | 153 | 163 | 173 | 188 | 202 | 222 | 250 | 0.1054 | 499 | 0.979 | 146.17 | 42.01 | 2 | 0.4618 | 351 | 0.0030 | 36.55 | 6.002 | 0.2222 | 35909.5 | 7530000 | 1680000000 | 400000000000 | 0.4861 | 0.1592 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0652 | 0.0044 | 0.0966 | 0.0175 | 0.1473 | 0.0773 | 0.1546 | 0.0962 | 0.1812 | 0.0845 | 0.1594 | 0.0962 | 0.1860 | 0.6239 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0297 | 0.0054 | 0.0822 | 0.0549 | 0.1154 | 0.0776 | 0.1136 | 0.0415 | 0.1416 | 0.0776 | 0.5105 | 0.7430 | 0.0000 | 0.0000 | 0.0063 | 0.0000 | 0.0253 | 0.0328 | 0.0823 | 0.2131 | 0.2595 | 0.2295 | 0.1329 | 0.2131 | 0.1139 | 0.0984 | 0.1835 | 0.1311 | 0.1962 | 0.0820 | 0.0000 | 0.0000 | 0.0150 | 0.0300 | 0.1502 | 0.1922 | 0.0991 | 0.1381 | 0.3754 | 7 | 8 | 10 | 12 | 18 | 39 | 88 | 210 | 496 | 0.1437 | 25.58 | 4.029 | 0.5929 | 82762.0 | 66600000 | 60800000000 | 59600000000000 | 0.6762 | 0.0517 | 0.0645 | 0.0022 | 0.2719 | 0.0410 | 0.3548 | 0.1339 | 0.1475 | 0.2009 | 0.0876 | 0.2203 | 0.0553 | 0.1749 | 0.0138 | 0.1058 | 0.0046 | 0.0756 | 0.0000 | 0.0454 | 0.0008 | 0.0000 | 0.0000 | 0.0007 | 0.0008 | 0.0007 | 0.0094 | 0.0131 | 0.0602 | 0.0518 | 0.1063 | 0.0801 | 0.0493 | 0.0608 | 0.1009 | 0.0849 | 0.6724 | 0.7079 | 0.0000 | 0.0000 | 0.0019 | 0.0020 | 0.0028 | 0.0020 | 0.0104 | 0.0132 | 0.0669 | 0.0731 | 0.1121 | 0.1015 | 0.0574 | 0.0701 | 0.0989 | 0.1036 | 0.6497 | 0.6345 | 0.0000 | 0.0000 | 0.0034 | 0.0086 | 0.0738 | 0.0935 | 0.0626 | 0.0995 | 0.6587 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 538 | 522 | | 10143 | 24967 | 137.2 | 45.41 | 180.80 | 230.55 | 91 | 101 | 110 | 118 | 127 | 137 | 150 | 167 | 198 | 0.0470 | 1173 | 0.400 | 194.49 | 33.54 | 5 | 0.0550 | 558 | 0.0019 | 26.27 | 6.724 | 0.2500 | 20883.8 | 3560000 | 679000000 | 145000000000 | 0.4664 | 0.1883 | 0.0012 | 0.0001 | 0.0036 | 0.0001 | 0.0091 | 0.0012 | 0.0383 | 0.0057 | 0.1113 | 0.0305 | 0.1764 | 0.0645 | 0.1603 | 0.0659 | 0.1744 | 0.0958 | 0.3255 | 0.7361 | 0.0007 | 0.0001 | 0.0021 | 0.0001 | 0.0034 | 0.0007 | 0.0142 | 0.0028 | 0.0411 | 0.0161 | 0.0774 | 0.0311 | 0.0693 | 0.0286 | 0.0908 | 0.0446 | 0.7011 | 0.8759 | 0.0032 | 0.0009 | 0.0055 | 0.0026 | 0.0120 | 0.0205 | 0.0443 | 0.0759 | 0.1061 | 0.1253 | 0.1513 | 0.1748 | 0.1070 | 0.1228 | 0.1402 | 0.1313 | 0.4304 | 0.3461 | 0.0022 | 0.0049 | 0.0080 | 0.0279 | 0.0670 | 0.1061 | 0.0989 | 0.1234 | 0.5616 | 11 | 13 | 17 | 26 | 61 | 137 | 226 | 346 | 527 | 0.0541 | 38.24 | 5.495 | 0.4994 | 85842.1 | 54700000 | 40900000000 | 34200000000000 | 0.5806 | 0.1163 | 0.0514 | 0.0037 | 0.1686 | 0.0204 | 0.2152 | 0.1049 | 0.1551 | 0.1368 | 0.1378 | 0.1772 | 0.1287 | 0.1802 | 0.0730 | 0.1206 | 0.0476 | 0.1111 | 0.0226 | 0.1450 | 0.0004 | 0.0003 | 0.0008 | 0.0002 | 0.0017 | 0.0011 | 0.0086 | 0.0061 | 0.0487 | 0.0419 | 0.0930 | 0.0753 | 0.0691 | 0.0562 | 0.0965 | 0.0845 | 0.6812 | 0.7344 | 0.0005 | 0.0003 | 0.0014 | 0.0013 | 0.0031 | 0.0041 | 0.0161 | 0.0199 | 0.0661 | 0.0733 | 0.1165 | 0.1280 | 0.0805 | 0.0882 | 0.1160 | 0.1179 | 0.5998 | 0.5670 | 0.0002 | 0.0007 | 0.0022 | 0.0128 | 0.0574 | 0.1049 | 0.0737 | 0.1099 | 0.6383 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 541 | 522 | | 7538 | 10729 | 182.1 | 53.16 | 151.55 | 105.15 | 123 | 138 | 150 | 162 | 173 | 185 | 200 | 220 | 253 | 0.0842 | 903 | 1.033 | 124.56 | 28.32 | 1 | 0.0358 | 270 | 0.0011 | 47.33 | 7.166 | 0.1859 | 35971.8 | 7740000 | 1820000000 | 464000000000 | 0.4607 | 0.1986 | 0.0008 | 0.0002 | 0.0033 | 0.0003 | 0.0110 | 0.0014 | 0.0358 | 0.0038 | 0.1099 | 0.0259 | 0.1983 | 0.0649 | 0.1693 | 0.0640 | 0.1888 | 0.0978 | 0.2827 | 0.7419 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0075 | 0.0010 | 0.0464 | 0.0143 | 0.0907 | 0.0329 | 0.0762 | 0.0285 | 0.1180 | 0.0474 | 0.6588 | 0.8759 | 0.0038 | 0.0055 | 0.0070 | 0.0083 | 0.0203 | 0.0290 | 0.0725 | 0.0981 | 0.1462 | 0.1630 | 0.1697 | 0.2003 | 0.1132 | 0.1077 | 0.1373 | 0.1436 | 0.3299 | 0.2445 | 0.0003 | 0.0050 | 0.0050 | 0.0400 | 0.1026 | 0.1488 | 0.1079 | 0.1417 | 0.4487 | 38 | 59 | 80 | 102 | 128 | 157 | 190 | 236 | 297 | 0.0020 | 46.88 | 6.872 | 0.2760 | 34024.8 | 9800000 | 3360000000 | 1320000000000 | 0.5574 | 0.1310 | 0.0165 | 0.0000 | 0.1056 | 0.0050 | 0.2130 | 0.0382 | 0.1703 | 0.0893 | 0.1387 | 0.1551 | 0.1488 | 0.2086 | 0.0826 | 0.1535 | 0.0716 | 0.1259 | 0.0528 | 0.2244 | 0.0005 | 0.0000 | 0.0002 | 0.0006 | 0.0020 | 0.0016 | 0.0138 | 0.0112 | 0.0620 | 0.0424 | 0.1227 | 0.0865 | 0.0888 | 0.0730 | 0.1299 | 0.1037 | 0.5802 | 0.6811 | 0.0006 | 0.0004 | 0.0029 | 0.0049 | 0.0119 | 0.0162 | 0.0365 | 0.0503 | 0.1192 | 0.1521 | 0.1812 | 0.1923 | 0.1190 | 0.1367 | 0.1520 | 0.1559 | 0.3768 | 0.2911 | 0.0002 | 0.0009 | 0.0049 | 0.0238 | 0.0980 | 0.1462 | 0.1128 | 0.1557 | 0.4576 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 547 | 120 | | 5210 | 7031 | 116.5 | 33.51 | 67.29 | 88.49 | 82 | 90 | 96 | 102 | 109 | 116 | 126 | 140 | 161 | 0.1074 | 755 | 0.962 | 86.27 | 33.84 | 2 | 0.0478 | 249 | 0.0029 | 20.97 | 6.262 | 0.2723 | 14702.5 | 2030000 | 306000000 | 50600000000 | 0.4062 | 0.2387 | 0.0018 | 0.0000 | 0.0032 | 0.0000 | 0.0093 | 0.0009 | 0.0370 | 0.0017 | 0.1025 | 0.0273 | 0.1787 | 0.0577 | 0.1630 | 0.0624 | 0.1798 | 0.0955 | 0.3247 | 0.7545 | 0.0010 | 0.0000 | 0.0021 | 0.0000 | 0.0044 | 0.0004 | 0.0154 | 0.0008 | 0.0427 | 0.0160 | 0.0740 | 0.0248 | 0.0717 | 0.0220 | 0.1040 | 0.0419 | 0.6847 | 0.8941 | 0.0019 | 0.0042 | 0.0049 | 0.0166 | 0.0165 | 0.0374 | 0.0525 | 0.0832 | 0.1380 | 0.1933 | 0.1672 | 0.2121 | 0.1263 | 0.0894 | 0.1545 | 0.1538 | 0.3382 | 0.2100 | 0.0039 | 0.0048 | 0.0101 | 0.0400 | 0.0761 | 0.1094 | 0.1104 | 0.1359 | 0.5094 | 12 | 15 | 20 | 26 | 33 | 43 | 64 | 100 | 163 | 0.0295 | 19.01 | 4.722 | 0.5549 | 12357.0 | 4090000 | 1840000000 | 978000000000 | 0.7256 | 0.0616 | 0.0176 | 0.0062 | 0.0821 | 0.0241 | 0.1437 | 0.0469 | 0.1935 | 0.0841 | 0.1686 | 0.1496 | 0.1569 | 0.1695 | 0.0997 | 0.1447 | 0.0982 | 0.1371 | 0.0396 | 0.2378 | 0.0025 | 0.0024 | 0.0050 | 0.0041 | 0.0103 | 0.0111 | 0.0227 | 0.0199 | 0.0900 | 0.0827 | 0.1399 | 0.1253 | 0.0929 | 0.0918 | 0.1312 | 0.1236 | 0.5056 | 0.5392 | 0.0011 | 0.0020 | 0.0092 | 0.0033 | 0.0075 | 0.0139 | 0.0316 | 0.0463 | 0.1086 | 0.1026 | 0.1580 | 0.1794 | 0.1080 | 0.1112 | 0.1356 | 0.1456 | 0.4406 | 0.3958 | 0.0034 | 0.0034 | 0.0112 | 0.0244 | 0.0937 | 0.1541 | 0.0941 | 0.1332 | 0.4824 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 547 | 289 | | 11285 | 27072 | 244.5 | 58.73 | 197.38 | 232.26 | 172 | 193 | 209 | 224 | 239 | 255 | 274 | 296 | 325 | 0.0436 | 1181 | 1.186 | 113.74 | 45.89 | 1 | 0.0262 | 296 | 0.0006 | 59.04 | 7.598 | 0.1608 | 63242.6 | 17200000 | 4920000000 | 1470000000000 | 0.4595 | 0.1977 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0003 | 0.0222 | 0.0030 | 0.0838 | 0.0183 | 0.1665 | 0.0428 | 0.1519 | 0.0447 | 0.1695 | 0.0687 | 0.4015 | 0.8221 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0009 | 0.0000 | 0.0056 | 0.0015 | 0.0329 | 0.0117 | 0.0689 | 0.0232 | 0.0624 | 0.0202 | 0.0836 | 0.0302 | 0.7454 | 0.9132 | 0.0042 | 0.0118 | 0.0042 | 0.0251 | 0.0161 | 0.0340 | 0.0589 | 0.0991 | 0.1158 | 0.1731 | 0.1866 | 0.1864 | 0.1001 | 0.1080 | 0.1387 | 0.1391 | 0.3753 | 0.2234 | 0.0010 | 0.0019 | 0.0079 | 0.0250 | 0.0784 | 0.1238 | 0.0992 | 0.1291 | 0.5338 | 14 | 18 | 26 | 48 | 94 | 162 | 255 | 375 | 541 | 0.0240 | 59.33 | 6.100 | 0.4045 | 92900.8 | 59800000 | 46700000000 | 42500000000000 | 0.3821 | 0.2440 | 0.0415 | 0.0013 | 0.1747 | 0.0119 | 0.3178 | 0.1184 | 0.1407 | 0.1403 | 0.1199 | 0.1896 | 0.0884 | 0.1946 | 0.0465 | 0.1232 | 0.0336 | 0.1013 | 0.0369 | 0.1196 | 0.0001 | 0.0002 | 0.0000 | 0.0003 | 0.0009 | 0.0010 | 0.0080 | 0.0057 | 0.0480 | 0.0394 | 0.0973 | 0.0776 | 0.0603 | 0.0509 | 0.0905 | 0.0756 | 0.6949 | 0.7492 | 0.0002 | 0.0004 | 0.0020 | 0.0014 | 0.0027 | 0.0026 | 0.0159 | 0.0171 | 0.0664 | 0.0775 | 0.1207 | 0.1335 | 0.0813 | 0.0857 | 0.1106 | 0.1232 | 0.6001 | 0.5585 | 0.0001 | 0.0006 | 0.0019 | 0.0122 | 0.0586 | 0.1142 | 0.0705 | 0.1007 | 0.6412 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 550 | 347 | | 2625 | 7570 | 364.6 | 100.61 | 57.27 | 93.59 | 229 | 271 | 313 | 338 | 359 | 381 | 405 | 462 | 513 | 0.0856 | 648 | 0.595 | 111.40 | 19.31 | 7 | 0.1051 | 276 | 0.0012 | 33.64 | 6.958 | 0.2138 | 143052.0 | 59700000 | 26200000000 | 12000000000000 | 0.3697 | 0.2506 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0007 | 0.0023 | 0.0162 | 0.0079 | 0.0855 | 0.0410 | 0.1179 | 0.0843 | 0.0929 | 0.0531 | 0.0899 | 0.0754 | 0.5969 | 0.7346 | 0.0000 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0035 | 0.0016 | 0.0333 | 0.0276 | 0.0455 | 0.0470 | 0.0414 | 0.0272 | 0.0510 | 0.0404 | 0.8253 | 0.8549 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0000 | 0.0216 | 0.0225 | 0.0396 | 0.0722 | 0.1367 | 0.1075 | 0.2086 | 0.0690 | 0.1223 | 0.1043 | 0.1295 | 0.6244 | 0.3309 | 0.0000 | 0.0008 | 0.0048 | 0.0191 | 0.0590 | 0.0901 | 0.0726 | 0.0989 | 0.6547 | 8 | 10 | 12 | 14 | 18 | 23 | 38 | 87 | 161 | 0.1461 | 5.86 | 3.394 | 0.7357 | 12038.0 | 4300000 | 1950000000 | 1010000000000 | 0.6794 | 0.0692 | 0.0238 | 0.0092 | 0.0506 | 0.0184 | 0.1131 | 0.0407 | 0.1310 | 0.0512 | 0.2292 | 0.1168 | 0.2083 | 0.1444 | 0.1280 | 0.1470 | 0.0893 | 0.1745 | 0.0268 | 0.2979 | 0.0019 | 0.0025 | 0.0014 | 0.0038 | 0.0068 | 0.0059 | 0.0106 | 0.0106 | 0.0323 | 0.0317 | 0.0651 | 0.0571 | 0.0458 | 0.0440 | 0.0719 | 0.0693 | 0.7641 | 0.7751 | 0.0006 | 0.0000 | 0.0012 | 0.0006 | 0.0035 | 0.0075 | 0.0098 | 0.0106 | 0.0368 | 0.0399 | 0.0725 | 0.0761 | 0.0478 | 0.0586 | 0.0725 | 0.0773 | 0.7553 | 0.7294 | 0.0005 | 0.0011 | 0.0053 | 0.0090 | 0.0329 | 0.0638 | 0.0515 | 0.0733 | 0.7625 |