High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 559 | 397 | | 4059 | 4987 | 157.3 | 43.64 | 166.74 | 137.41 | 113 | 123 | 131 | 139 | 148 | 157 | 168 | 187 | 216 | 0.1313 | 655 | 1.114 | 90.61 | 28.23 | 1 | 0.0532 | 216 | 0.0019 | 30.80 | 6.626 | 0.2263 | 26652.8 | 4910000 | 989000000 | 219000000000 | 0.4120 | 0.2290 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0082 | 0.0005 | 0.0341 | 0.0027 | 0.0928 | 0.0269 | 0.1428 | 0.0626 | 0.1670 | 0.0541 | 0.1833 | 0.0802 | 0.3697 | 0.7729 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0039 | 0.0002 | 0.0135 | 0.0015 | 0.0410 | 0.0154 | 0.0693 | 0.0336 | 0.0738 | 0.0197 | 0.1013 | 0.0351 | 0.6956 | 0.8945 | 0.0051 | 0.0053 | 0.0064 | 0.0132 | 0.0128 | 0.0079 | 0.0370 | 0.1164 | 0.1392 | 0.1138 | 0.1520 | 0.2063 | 0.1137 | 0.1190 | 0.1494 | 0.1349 | 0.3844 | 0.2831 | 0.0006 | 0.0043 | 0.0188 | 0.0389 | 0.0832 | 0.1269 | 0.1014 | 0.1263 | 0.4997 | 31 | 49 | 69 | 94 | 126 | 164 | 210 | 272 | 369 | 0.0031 | 48.39 | 6.631 | 0.2926 | 46678.1 | 17300000 | 7530000000 | 3680000000000 | 0.5082 | 0.1638 | 0.0343 | 0.0038 | 0.1220 | 0.0131 | 0.1792 | 0.0451 | 0.1868 | 0.1264 | 0.1753 | 0.1496 | 0.1334 | 0.2034 | 0.0940 | 0.1508 | 0.0445 | 0.1189 | 0.0305 | 0.1890 | 0.0004 | 0.0007 | 0.0034 | 0.0014 | 0.0038 | 0.0031 | 0.0290 | 0.0239 | 0.0720 | 0.0560 | 0.1195 | 0.1000 | 0.0909 | 0.0796 | 0.1136 | 0.1058 | 0.5673 | 0.6295 | 0.0025 | 0.0023 | 0.0019 | 0.0023 | 0.0120 | 0.0232 | 0.0340 | 0.0518 | 0.1051 | 0.1044 | 0.1385 | 0.1353 | 0.0906 | 0.1067 | 0.1284 | 0.1276 | 0.4871 | 0.4462 | 0.0000 | 0.0061 | 0.0096 | 0.0289 | 0.0851 | 0.1327 | 0.0917 | 0.1155 | 0.5304 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 603 | 689 | | 7600 | 15811 | 210.9 | 43.78 | 142.17 | 171.25 | 159 | 173 | 185 | 196 | 207 | 218 | 230 | 245 | 269 | 0.0623 | 985 | 1.140 | 88.32 | 39.01 | 1 | 0.0330 | 251 | 0.0011 | 39.63 | 7.083 | 0.1887 | 46382.0 | 10600000 | 2540000000 | 632000000000 | 0.4649 | 0.1876 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0031 | 0.0000 | 0.0156 | 0.0013 | 0.0581 | 0.0167 | 0.1363 | 0.0365 | 0.1516 | 0.0327 | 0.1761 | 0.0584 | 0.4584 | 0.8545 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0074 | 0.0004 | 0.0307 | 0.0110 | 0.0643 | 0.0228 | 0.0646 | 0.0137 | 0.0939 | 0.0247 | 0.7375 | 0.9274 | 0.0050 | 0.0238 | 0.0058 | 0.0149 | 0.0284 | 0.0387 | 0.0984 | 0.1310 | 0.1418 | 0.1786 | 0.1818 | 0.1994 | 0.0992 | 0.1012 | 0.1276 | 0.1250 | 0.3119 | 0.1875 | 0.0009 | 0.0020 | 0.0111 | 0.0386 | 0.0873 | 0.1384 | 0.1199 | 0.1335 | 0.4684 | 11 | 13 | 15 | 21 | 53 | 120 | 192 | 279 | 392 | 0.0646 | 26.36 | 5.217 | 0.4922 | 49534.8 | 23000000 | 12600000000 | 7870000000000 | 0.5544 | 0.1062 | 0.0575 | 0.0021 | 0.2553 | 0.0185 | 0.3274 | 0.1627 | 0.1596 | 0.1906 | 0.0883 | 0.1964 | 0.0624 | 0.1886 | 0.0300 | 0.1011 | 0.0130 | 0.0719 | 0.0065 | 0.0682 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0005 | 0.0010 | 0.0079 | 0.0052 | 0.0517 | 0.0451 | 0.0963 | 0.0833 | 0.0703 | 0.0593 | 0.0991 | 0.0835 | 0.6739 | 0.7223 | 0.0002 | 0.0004 | 0.0013 | 0.0015 | 0.0029 | 0.0043 | 0.0140 | 0.0201 | 0.0689 | 0.0788 | 0.1235 | 0.1391 | 0.0936 | 0.0936 | 0.1214 | 0.1176 | 0.5743 | 0.5445 | 0.0000 | 0.0003 | 0.0017 | 0.0095 | 0.0610 | 0.1104 | 0.0758 | 0.1149 | 0.6263 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 203 | 497 | | 8616 | 14575 | 174.6 | 44.13 | 171.91 | 149.45 | 122 | 138 | 150 | 161 | 171 | 181 | 192 | 207 | 232 | 0.0673 | 981 | 1.044 | 125.32 | 34.48 | 1 | 0.0331 | 285 | 0.0012 | 38.52 | 7.056 | 0.1977 | 32427.2 | 6400000 | 1340000000 | 300000000000 | 0.4569 | 0.1989 | 0.0000 | 0.0000 | 0.0017 | 0.0001 | 0.0078 | 0.0003 | 0.0287 | 0.0031 | 0.0888 | 0.0227 | 0.1586 | 0.0483 | 0.1617 | 0.0556 | 0.1808 | 0.0817 | 0.3720 | 0.7881 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0011 | 0.0383 | 0.0140 | 0.0683 | 0.0253 | 0.0693 | 0.0240 | 0.0973 | 0.0396 | 0.7154 | 0.8960 | 0.0043 | 0.0068 | 0.0129 | 0.0307 | 0.0302 | 0.0341 | 0.0851 | 0.1022 | 0.1424 | 0.1959 | 0.1763 | 0.1959 | 0.1128 | 0.1141 | 0.1375 | 0.1210 | 0.2984 | 0.1993 | 0.0015 | 0.0050 | 0.0118 | 0.0350 | 0.0866 | 0.1316 | 0.1178 | 0.1480 | 0.4626 | 22 | 43 | 68 | 99 | 135 | 170 | 218 | 279 | 376 | 0.0026 | 76.94 | 7.156 | 0.2520 | 51884.8 | 21400000 | 11000000000 | 6610000000000 | 0.4445 | 0.1894 | 0.0210 | 0.0006 | 0.0998 | 0.0058 | 0.1884 | 0.0378 | 0.1768 | 0.0812 | 0.1748 | 0.1518 | 0.1509 | 0.1963 | 0.0944 | 0.1541 | 0.0536 | 0.1491 | 0.0404 | 0.2232 | 0.0008 | 0.0002 | 0.0013 | 0.0005 | 0.0043 | 0.0019 | 0.0145 | 0.0096 | 0.0545 | 0.0413 | 0.1088 | 0.0813 | 0.0850 | 0.0660 | 0.1138 | 0.0944 | 0.6169 | 0.7048 | 0.0008 | 0.0011 | 0.0042 | 0.0066 | 0.0085 | 0.0130 | 0.0307 | 0.0414 | 0.0827 | 0.0900 | 0.1433 | 0.1572 | 0.1056 | 0.1118 | 0.1272 | 0.1359 | 0.4970 | 0.4431 | 0.0005 | 0.0029 | 0.0095 | 0.0225 | 0.0731 | 0.1165 | 0.1001 | 0.1229 | 0.5519 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1078 | 76 | | 3929 | 6047 | 161.4 | 44.19 | 132.87 | 179.68 | 115 | 126 | 135 | 144 | 153 | 164 | 177 | 192 | 220 | 0.1057 | 639 | 1.011 | 168.43 | 62.07 | 1 | 0.1168 | 459 | 0.0015 | 39.33 | 6.819 | 0.1959 | 28002.9 | 5250000 | 1070000000 | 240000000000 | 0.4412 | 0.2076 | 0.0013 | 0.0000 | 0.0035 | 0.0003 | 0.0083 | 0.0017 | 0.0372 | 0.0034 | 0.0959 | 0.0278 | 0.1713 | 0.0613 | 0.1827 | 0.0573 | 0.1866 | 0.0994 | 0.3132 | 0.7487 | 0.0010 | 0.0000 | 0.0007 | 0.0003 | 0.0023 | 0.0003 | 0.0128 | 0.0000 | 0.0437 | 0.0177 | 0.0801 | 0.0303 | 0.0782 | 0.0230 | 0.1120 | 0.0483 | 0.6693 | 0.8803 | 0.0066 | 0.0058 | 0.0092 | 0.0203 | 0.0328 | 0.0407 | 0.0814 | 0.0872 | 0.1273 | 0.1802 | 0.1654 | 0.2122 | 0.1247 | 0.1105 | 0.1535 | 0.1337 | 0.2992 | 0.2093 | 0.0035 | 0.0035 | 0.0106 | 0.0388 | 0.1052 | 0.1240 | 0.1217 | 0.1499 | 0.4427 | 9 | 12 | 16 | 25 | 49 | 95 | 150 | 233 | 366 | 0.0201 | 68.11 | 5.908 | 0.3842 | 49932.6 | 27200000 | 17800000000 | 13000000000000 | 0.5438 | 0.1149 | 0.0657 | 0.0029 | 0.2044 | 0.0115 | 0.2117 | 0.1319 | 0.1387 | 0.1616 | 0.1515 | 0.2122 | 0.0985 | 0.1539 | 0.0511 | 0.1023 | 0.0547 | 0.0918 | 0.0237 | 0.1319 | 0.0004 | 0.0000 | 0.0018 | 0.0004 | 0.0009 | 0.0031 | 0.0234 | 0.0147 | 0.0661 | 0.0570 | 0.0974 | 0.0892 | 0.0793 | 0.0694 | 0.1058 | 0.0927 | 0.6249 | 0.6735 | 0.0017 | 0.0007 | 0.0006 | 0.0000 | 0.0076 | 0.0046 | 0.0285 | 0.0359 | 0.0802 | 0.0894 | 0.1197 | 0.1305 | 0.0953 | 0.0868 | 0.1104 | 0.1194 | 0.5561 | 0.5329 | 0.0010 | 0.0030 | 0.0081 | 0.0186 | 0.0756 | 0.1149 | 0.0832 | 0.1144 | 0.5811 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 218 | 312 | | 2655 | 8245 | 132.8 | 44.21 | 178.73 | 118.36 | 91 | 99 | 108 | 117 | 125 | 134 | 142 | 155 | 176 | 0.0813 | 670 | 0.683 | 79.32 | 27.66 | 1 | 0.0968 | 257 | 0.0031 | 18.62 | 6.095 | 0.3246 | 19582.2 | 3340000 | 689000000 | 173000000000 | 0.4385 | 0.1979 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0062 | 0.0004 | 0.0256 | 0.0020 | 0.0622 | 0.0283 | 0.1119 | 0.0557 | 0.1140 | 0.0414 | 0.1298 | 0.0602 | 0.5497 | 0.8120 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0037 | 0.0004 | 0.0115 | 0.0015 | 0.0314 | 0.0216 | 0.0492 | 0.0352 | 0.0413 | 0.0250 | 0.0581 | 0.0367 | 0.8043 | 0.8796 | 0.0043 | 0.0000 | 0.0065 | 0.0100 | 0.0151 | 0.0100 | 0.0454 | 0.0350 | 0.1080 | 0.1100 | 0.1058 | 0.1600 | 0.0778 | 0.0750 | 0.1231 | 0.1350 | 0.5140 | 0.4650 | 0.0027 | 0.0018 | 0.0100 | 0.0255 | 0.0656 | 0.0974 | 0.0792 | 0.1193 | 0.5984 | 59 | 76 | 93 | 115 | 144 | 182 | 225 | 275 | 351 | 0.0020 | 52.90 | 6.928 | 0.2551 | 45949.6 | 15000000 | 5740000000 | 2430000000000 | 0.5074 | 0.1593 | 0.0155 | 0.0010 | 0.0882 | 0.0092 | 0.2007 | 0.0209 | 0.1771 | 0.0654 | 0.1630 | 0.1485 | 0.1441 | 0.1660 | 0.0774 | 0.1622 | 0.0566 | 0.1523 | 0.0774 | 0.2745 | 0.0005 | 0.0002 | 0.0027 | 0.0019 | 0.0060 | 0.0044 | 0.0169 | 0.0095 | 0.0638 | 0.0525 | 0.1051 | 0.0712 | 0.0744 | 0.0711 | 0.1097 | 0.0969 | 0.6210 | 0.6922 | 0.0011 | 0.0039 | 0.0068 | 0.0123 | 0.0139 | 0.0178 | 0.0444 | 0.0468 | 0.0889 | 0.0868 | 0.1213 | 0.1391 | 0.0998 | 0.1297 | 0.1348 | 0.1440 | 0.4889 | 0.4196 | 0.0009 | 0.0036 | 0.0083 | 0.0238 | 0.0753 | 0.1202 | 0.0940 | 0.1196 | 0.5542 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 343 | 118 | | 16901 | 26398 | 141.3 | 44.30 | 218.23 | 252.21 | 94 | 105 | 114 | 123 | 132 | 143 | 157 | 175 | 204 | 0.0815 | 2151 | 0.681 | 101.95 | 26.17 | 6 | 0.0180 | 304 | 0.0015 | 29.37 | 6.914 | 0.2233 | 21941.5 | 3740000 | 696000000 | 140000000000 | 0.5305 | 0.1501 | 0.0011 | 0.0003 | 0.0048 | 0.0008 | 0.0158 | 0.0020 | 0.0410 | 0.0075 | 0.1072 | 0.0328 | 0.1650 | 0.0728 | 0.1666 | 0.0720 | 0.1890 | 0.1025 | 0.3095 | 0.7093 | 0.0006 | 0.0002 | 0.0026 | 0.0004 | 0.0058 | 0.0011 | 0.0146 | 0.0036 | 0.0408 | 0.0175 | 0.0693 | 0.0366 | 0.0679 | 0.0300 | 0.0954 | 0.0486 | 0.7030 | 0.8620 | 0.0021 | 0.0030 | 0.0070 | 0.0090 | 0.0120 | 0.0200 | 0.0527 | 0.0656 | 0.1020 | 0.1512 | 0.1411 | 0.1773 | 0.1049 | 0.1097 | 0.1331 | 0.1607 | 0.4451 | 0.3035 | 0.0015 | 0.0049 | 0.0131 | 0.0289 | 0.0754 | 0.1125 | 0.0940 | 0.1202 | 0.5495 | 20 | 29 | 48 | 79 | 120 | 175 | 259 | 375 | 570 | 0.0118 | 66.19 | 6.470 | 0.3644 | 111232.0 | 85900000 | 88000000000 | 113000000000000 | 0.5942 | 0.0903 | 0.0589 | 0.0022 | 0.1898 | 0.0187 | 0.2385 | 0.1095 | 0.1625 | 0.1457 | 0.1298 | 0.1893 | 0.1051 | 0.1818 | 0.0549 | 0.1192 | 0.0407 | 0.1100 | 0.0196 | 0.1236 | 0.0006 | 0.0005 | 0.0022 | 0.0016 | 0.0043 | 0.0051 | 0.0185 | 0.0152 | 0.0708 | 0.0630 | 0.1147 | 0.0979 | 0.0818 | 0.0754 | 0.1208 | 0.1064 | 0.5863 | 0.6349 | 0.0003 | 0.0018 | 0.0031 | 0.0043 | 0.0077 | 0.0110 | 0.0323 | 0.0372 | 0.0907 | 0.0969 | 0.1399 | 0.1479 | 0.1021 | 0.1013 | 0.1285 | 0.1341 | 0.4956 | 0.4656 | 0.0010 | 0.0025 | 0.0059 | 0.0245 | 0.0763 | 0.1324 | 0.0895 | 0.1228 | 0.5449 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 916 | 643 | | 6177 | 7967 | 199.4 | 44.34 | 175.07 | 133.71 | 150 | 163 | 173 | 182 | 192 | 203 | 216 | 234 | 259 | 0.0964 | 768 | 0.994 | 106.57 | 33.42 | 1 | 0.0440 | 272 | 0.0013 | 36.60 | 6.944 | 0.1957 | 41711.5 | 9180000 | 2130000000 | 520000000000 | 0.4243 | 0.2275 | 0.0010 | 0.0000 | 0.0007 | 0.0000 | 0.0032 | 0.0000 | 0.0168 | 0.0009 | 0.0753 | 0.0176 | 0.1308 | 0.0425 | 0.1402 | 0.0375 | 0.1836 | 0.0678 | 0.4482 | 0.8336 | 0.0006 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0000 | 0.0076 | 0.0005 | 0.0326 | 0.0112 | 0.0591 | 0.0230 | 0.0595 | 0.0150 | 0.0870 | 0.0231 | 0.7518 | 0.9272 | 0.0009 | 0.0179 | 0.0091 | 0.0358 | 0.0174 | 0.0657 | 0.0659 | 0.1343 | 0.1473 | 0.1433 | 0.1738 | 0.1791 | 0.1363 | 0.0955 | 0.1537 | 0.1164 | 0.2955 | 0.2119 | 0.0011 | 0.0033 | 0.0110 | 0.0375 | 0.0824 | 0.1191 | 0.1085 | 0.1393 | 0.4978 | 30 | 56 | 84 | 112 | 145 | 182 | 223 | 277 | 360 | 0.0025 | 69.87 | 6.927 | 0.2586 | 48522.6 | 17600000 | 7750000000 | 3970000000000 | 0.4873 | 0.1778 | 0.0220 | 0.0017 | 0.1111 | 0.0031 | 0.1870 | 0.0584 | 0.1544 | 0.1117 | 0.1816 | 0.1633 | 0.1457 | 0.1879 | 0.0951 | 0.1507 | 0.0552 | 0.1240 | 0.0479 | 0.1992 | 0.0002 | 0.0004 | 0.0014 | 0.0006 | 0.0029 | 0.0018 | 0.0145 | 0.0127 | 0.0737 | 0.0543 | 0.1090 | 0.0980 | 0.0872 | 0.0692 | 0.1206 | 0.1000 | 0.5904 | 0.6629 | 0.0015 | 0.0034 | 0.0019 | 0.0029 | 0.0087 | 0.0147 | 0.0417 | 0.0563 | 0.1059 | 0.1337 | 0.1647 | 0.1768 | 0.1097 | 0.1254 | 0.1514 | 0.1528 | 0.4144 | 0.3340 | 0.0006 | 0.0033 | 0.0072 | 0.0275 | 0.0899 | 0.1341 | 0.1039 | 0.1338 | 0.4997 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1197 | 726 | | 3699 | 9192 | 137.4 | 44.39 | 37.17 | 36.11 | 98 | 107 | 113 | 119 | 127 | 135 | 146 | 160 | 187 | 0.0926 | 851 | 1.180 | 107.28 | 41.01 | 1 | 0.0746 | 276 | 0.0024 | 30.51 | 6.416 | 0.2449 | 20843.7 | 3610000 | 733000000 | 177000000000 | 0.4112 | 0.2401 | 0.0009 | 0.0003 | 0.0037 | 0.0006 | 0.0107 | 0.0009 | 0.0409 | 0.0027 | 0.0991 | 0.0285 | 0.1647 | 0.0612 | 0.1629 | 0.0558 | 0.2010 | 0.0876 | 0.3160 | 0.7623 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0050 | 0.0000 | 0.0210 | 0.0014 | 0.0522 | 0.0177 | 0.0878 | 0.0343 | 0.0906 | 0.0296 | 0.1372 | 0.0500 | 0.6048 | 0.8670 | 0.0060 | 0.0031 | 0.0105 | 0.0031 | 0.0180 | 0.0251 | 0.0481 | 0.0721 | 0.1008 | 0.1755 | 0.1474 | 0.1850 | 0.1158 | 0.1129 | 0.1549 | 0.1348 | 0.3985 | 0.2884 | 0.0049 | 0.0084 | 0.0182 | 0.0477 | 0.0869 | 0.1170 | 0.0953 | 0.0988 | 0.5228 | 9 | 13 | 17 | 21 | 25 | 32 | 40 | 53 | 80 | 0.0260 | 5.48 | 4.415 | 0.5610 | 2685.3 | 330423 | 59700000 | 14100000000 | 0.5938 | 0.1120 | 0.0235 | 0.0088 | 0.0780 | 0.0186 | 0.1751 | 0.0368 | 0.2151 | 0.0862 | 0.2240 | 0.1372 | 0.1421 | 0.1696 | 0.0882 | 0.1863 | 0.0406 | 0.1875 | 0.0133 | 0.1690 | 0.0060 | 0.0053 | 0.0070 | 0.0086 | 0.0141 | 0.0129 | 0.0319 | 0.0244 | 0.0718 | 0.0561 | 0.1115 | 0.0821 | 0.1027 | 0.0929 | 0.1364 | 0.1305 | 0.5185 | 0.5871 | 0.0033 | 0.0083 | 0.0129 | 0.0119 | 0.0220 | 0.0217 | 0.0407 | 0.0620 | 0.1073 | 0.1168 | 0.1401 | 0.1302 | 0.1052 | 0.1111 | 0.1393 | 0.1292 | 0.4291 | 0.4088 | 0.0032 | 0.0106 | 0.0122 | 0.0448 | 0.0860 | 0.1246 | 0.1159 | 0.1259 | 0.4767 | ||
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 328 | 685 | | 3310 | 17319 | 115.5 | 44.52 | 5.43 | 1.99 | 62 | 70 | 80 | 93 | 109 | 124 | 140 | 161 | 181 | 0.0577 | 999 | 0.991 | 31.40 | 10.77 | 2 | 0.0266 | 88 | 0.0050 | 4.21 | 5.619 | 0.4414 | 15310.3 | 2260000 | 362000000 | 61100000000 | 0.3498 | 0.2779 | 0.0021 | 0.0010 | 0.0072 | 0.0039 | 0.0123 | 0.0093 | 0.0349 | 0.0181 | 0.0739 | 0.0366 | 0.1242 | 0.0439 | 0.1232 | 0.0649 | 0.1828 | 0.0825 | 0.4394 | 0.7399 | 0.0005 | 0.0007 | 0.0015 | 0.0026 | 0.0035 | 0.0048 | 0.0089 | 0.0096 | 0.0212 | 0.0177 | 0.0227 | 0.0184 | 0.0257 | 0.0302 | 0.0420 | 0.0350 | 0.8741 | 0.8809 | 0.0010 | 0.0000 | 0.0019 | 0.0045 | 0.0086 | 0.0106 | 0.0209 | 0.0151 | 0.0409 | 0.0452 | 0.0571 | 0.0603 | 0.0523 | 0.0724 | 0.0647 | 0.0799 | 0.7526 | 0.7119 | 0.0013 | 0.0000 | 0.0013 | 0.0097 | 0.0232 | 0.0387 | 0.0290 | 0.0574 | 0.8395 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.2714 | 0.47 | 1.049 | 0.6358 | 33.5 | 227.156 | 1669.44 | 13153.9 | 0.4485 | 0.2089 | 0.0313 | 0.0023 | 0.0940 | 0.0125 | 0.1602 | 0.0406 | 0.2077 | 0.0829 | 0.2080 | 0.1416 | 0.1737 | 0.2164 | 0.0888 | 0.2463 | 0.0321 | 0.1826 | 0.0043 | 0.0747 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0030 | 0.0008 | 0.0099 | 0.0050 | 0.0301 | 0.0153 | 0.0780 | 0.0258 | 0.2017 | 0.0630 | 0.3485 | 0.2345 | 0.3287 | 0.6554 | 0.0177 | 0.0768 | 0.0775 | 0.1643 | 0.1302 | 0.2136 | 0.1742 | 0.2130 | 0.1942 | 0.1573 | 0.1860 | 0.0951 | 0.1327 | 0.0548 | 0.0683 | 0.0195 | 0.0192 | 0.0057 | 0.0007 | 0.0109 | 0.0459 | 0.1123 | 0.1876 | 0.2387 | 0.2118 | 0.1393 | 0.0528 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 656 | 535 | | 6091 | 20546 | 242.4 | 44.53 | 137.26 | 192.39 | 187 | 203 | 216 | 228 | 239 | 251 | 264 | 280 | 303 | 0.0476 | 979 | 1.098 | 86.73 | 30.00 | 1 | 0.0368 | 224 | 0.0009 | 51.40 | 7.200 | 0.1626 | 60738.6 | 15700000 | 4190000000 | 1150000000000 | 0.4279 | 0.2267 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0124 | 0.0005 | 0.0636 | 0.0142 | 0.1292 | 0.0326 | 0.1368 | 0.0323 | 0.1768 | 0.0541 | 0.4789 | 0.8663 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0008 | 0.0000 | 0.0040 | 0.0002 | 0.0280 | 0.0117 | 0.0548 | 0.0216 | 0.0579 | 0.0143 | 0.0777 | 0.0241 | 0.7764 | 0.9281 | 0.0078 | 0.0464 | 0.0056 | 0.0265 | 0.0468 | 0.1126 | 0.1158 | 0.2649 | 0.1815 | 0.2119 | 0.2305 | 0.1854 | 0.1236 | 0.0795 | 0.1336 | 0.0530 | 0.1548 | 0.0199 | 0.0003 | 0.0010 | 0.0075 | 0.0369 | 0.0799 | 0.1438 | 0.1237 | 0.1565 | 0.4503 | 10 | 11 | 13 | 16 | 25 | 62 | 149 | 281 | 445 | 0.1040 | 21.77 | 4.771 | 0.5558 | 55854.0 | 29600000 | 17800000000 | 11700000000000 | 0.5221 | 0.1170 | 0.0474 | 0.0028 | 0.1966 | 0.0109 | 0.3034 | 0.1095 | 0.1798 | 0.1664 | 0.1433 | 0.2227 | 0.0870 | 0.1986 | 0.0267 | 0.1227 | 0.0128 | 0.0858 | 0.0030 | 0.0806 | 0.0003 | 0.0003 | 0.0009 | 0.0003 | 0.0017 | 0.0020 | 0.0094 | 0.0084 | 0.0422 | 0.0385 | 0.0682 | 0.0630 | 0.0444 | 0.0432 | 0.0669 | 0.0635 | 0.7660 | 0.7808 | 0.0002 | 0.0002 | 0.0002 | 0.0009 | 0.0014 | 0.0024 | 0.0088 | 0.0122 | 0.0505 | 0.0500 | 0.0741 | 0.0794 | 0.0549 | 0.0568 | 0.0763 | 0.0835 | 0.7338 | 0.7146 | 0.0005 | 0.0006 | 0.0024 | 0.0080 | 0.0436 | 0.0706 | 0.0510 | 0.0733 | 0.7499 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 764 | 823 | | 6160 | 9088 | 204.9 | 44.54 | 210.61 | 171.66 | 152 | 168 | 179 | 190 | 200 | 211 | 223 | 239 | 264 | 0.0980 | 891 | 1.013 | 96.21 | 25.02 | 1 | 0.0381 | 235 | 0.0012 | 43.96 | 7.040 | 0.1905 | 43952.7 | 9880000 | 2330000000 | 576000000000 | 0.4516 | 0.2009 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0159 | 0.0009 | 0.0737 | 0.0187 | 0.1409 | 0.0415 | 0.1416 | 0.0468 | 0.1792 | 0.0731 | 0.4452 | 0.8191 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0049 | 0.0002 | 0.0318 | 0.0125 | 0.0631 | 0.0233 | 0.0618 | 0.0189 | 0.0953 | 0.0339 | 0.7420 | 0.9113 | 0.0039 | 0.0160 | 0.0106 | 0.0543 | 0.0299 | 0.0607 | 0.0781 | 0.1182 | 0.1408 | 0.1725 | 0.2064 | 0.2013 | 0.1225 | 0.1182 | 0.1524 | 0.1054 | 0.2555 | 0.1534 | 0.0025 | 0.0032 | 0.0104 | 0.0365 | 0.0879 | 0.1397 | 0.1065 | 0.1415 | 0.4718 | 39 | 68 | 97 | 128 | 165 | 210 | 263 | 332 | 440 | 0.0016 | 92.09 | 7.254 | 0.2167 | 73819.8 | 36000000 | 22600000000 | 17500000000000 | 0.5552 | 0.1172 | 0.0288 | 0.0009 | 0.1403 | 0.0040 | 0.2442 | 0.0581 | 0.1735 | 0.1210 | 0.1653 | 0.1922 | 0.1083 | 0.2065 | 0.0802 | 0.1390 | 0.0401 | 0.1287 | 0.0194 | 0.1496 | 0.0002 | 0.0002 | 0.0018 | 0.0009 | 0.0043 | 0.0038 | 0.0235 | 0.0144 | 0.0801 | 0.0642 | 0.1300 | 0.1163 | 0.1023 | 0.0810 | 0.1381 | 0.1164 | 0.5198 | 0.6028 | 0.0014 | 0.0031 | 0.0038 | 0.0031 | 0.0153 | 0.0206 | 0.0400 | 0.0601 | 0.1247 | 0.1250 | 0.1626 | 0.1737 | 0.1107 | 0.1123 | 0.1393 | 0.1368 | 0.4022 | 0.3654 | 0.0003 | 0.0006 | 0.0075 | 0.0304 | 0.1033 | 0.1536 | 0.1133 | 0.1467 | 0.4445 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 534 | 923 | | 4850 | 8622 | 162.0 | 44.63 | 180.98 | 189.76 | 115 | 127 | 136 | 144 | 153 | 163 | 176 | 194 | 220 | 0.0923 | 796 | 1.107 | 100.01 | 36.69 | 1 | 0.0542 | 263 | 0.0016 | 35.56 | 6.803 | 0.2042 | 28220.0 | 5320000 | 1090000000 | 244000000000 | 0.4589 | 0.1995 | 0.0007 | 0.0000 | 0.0029 | 0.0005 | 0.0119 | 0.0016 | 0.0353 | 0.0018 | 0.0965 | 0.0224 | 0.1780 | 0.0576 | 0.1567 | 0.0576 | 0.1780 | 0.0908 | 0.3401 | 0.7676 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0024 | 0.0000 | 0.0113 | 0.0004 | 0.0464 | 0.0146 | 0.0848 | 0.0310 | 0.0754 | 0.0240 | 0.1095 | 0.0437 | 0.6690 | 0.8863 | 0.0021 | 0.0124 | 0.0095 | 0.0173 | 0.0148 | 0.0173 | 0.0674 | 0.0990 | 0.1349 | 0.1708 | 0.1802 | 0.1931 | 0.1117 | 0.0990 | 0.1454 | 0.1411 | 0.3340 | 0.2500 | 0.0025 | 0.0020 | 0.0129 | 0.0373 | 0.0821 | 0.1318 | 0.1035 | 0.1274 | 0.5005 | 14 | 24 | 41 | 71 | 110 | 159 | 230 | 325 | 469 | 0.0065 | 92.57 | 6.832 | 0.2972 | 68756.7 | 35000000 | 20900000000 | 13800000000000 | 0.4654 | 0.1787 | 0.0372 | 0.0015 | 0.1157 | 0.0126 | 0.2314 | 0.0576 | 0.2038 | 0.0919 | 0.1826 | 0.1859 | 0.1210 | 0.2273 | 0.0605 | 0.1485 | 0.0297 | 0.1348 | 0.0180 | 0.1399 | 0.0011 | 0.0005 | 0.0019 | 0.0018 | 0.0057 | 0.0016 | 0.0164 | 0.0127 | 0.0655 | 0.0540 | 0.0911 | 0.0881 | 0.0668 | 0.0623 | 0.0898 | 0.0865 | 0.6617 | 0.6924 | 0.0018 | 0.0000 | 0.0015 | 0.0081 | 0.0066 | 0.0098 | 0.0239 | 0.0242 | 0.0668 | 0.0752 | 0.1146 | 0.1134 | 0.0856 | 0.0935 | 0.1050 | 0.1143 | 0.5942 | 0.5616 | 0.0003 | 0.0028 | 0.0070 | 0.0215 | 0.0579 | 0.0958 | 0.0730 | 0.1078 | 0.6339 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 68 | 826 | | 4128 | 6864 | 146.8 | 44.75 | 144.31 | 126.93 | 100 | 110 | 118 | 127 | 136 | 147 | 160 | 181 | 211 | 0.1005 | 690 | 1.168 | 86.40 | 31.91 | 1 | 0.0540 | 223 | 0.0017 | 33.02 | 6.715 | 0.2229 | 23554.4 | 4140000 | 797000000 | 166000000000 | 0.3837 | 0.2702 | 0.0030 | 0.0000 | 0.0044 | 0.0000 | 0.0178 | 0.0020 | 0.0435 | 0.0054 | 0.1156 | 0.0363 | 0.1789 | 0.0632 | 0.1848 | 0.0697 | 0.1912 | 0.1133 | 0.2609 | 0.7102 | 0.0021 | 0.0000 | 0.0021 | 0.0000 | 0.0065 | 0.0008 | 0.0174 | 0.0018 | 0.0533 | 0.0206 | 0.0793 | 0.0323 | 0.0854 | 0.0354 | 0.1083 | 0.0652 | 0.6456 | 0.8440 | 0.0011 | 0.0066 | 0.0033 | 0.0087 | 0.0299 | 0.0175 | 0.0421 | 0.0611 | 0.0965 | 0.1332 | 0.1275 | 0.1681 | 0.0976 | 0.1201 | 0.1197 | 0.1638 | 0.4823 | 0.3210 | 0.0024 | 0.0042 | 0.0180 | 0.0342 | 0.0792 | 0.1104 | 0.0870 | 0.1309 | 0.5336 | 30 | 44 | 59 | 79 | 101 | 131 | 171 | 232 | 322 | 0.0037 | 48.50 | 6.480 | 0.3040 | 36934.0 | 13300000 | 5910000000 | 3030000000000 | 0.5053 | 0.1536 | 0.0289 | 0.0009 | 0.1252 | 0.0109 | 0.1753 | 0.0639 | 0.1667 | 0.0948 | 0.1830 | 0.1501 | 0.1532 | 0.1791 | 0.0886 | 0.1497 | 0.0559 | 0.1542 | 0.0231 | 0.1964 | 0.0016 | 0.0003 | 0.0026 | 0.0026 | 0.0078 | 0.0059 | 0.0260 | 0.0221 | 0.0809 | 0.0635 | 0.1135 | 0.0910 | 0.0891 | 0.0846 | 0.1135 | 0.1116 | 0.5650 | 0.6183 | 0.0020 | 0.0018 | 0.0025 | 0.0077 | 0.0088 | 0.0196 | 0.0471 | 0.0422 | 0.0972 | 0.1040 | 0.1290 | 0.1337 | 0.1035 | 0.1040 | 0.1295 | 0.1349 | 0.4804 | 0.4522 | 0.0000 | 0.0060 | 0.0116 | 0.0344 | 0.0800 | 0.1244 | 0.1000 | 0.1224 | 0.5214 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 457 | 212 | | 6322 | 18147 | 382.8 | 44.78 | 238.77 | 294.82 | 326 | 348 | 362 | 373 | 384 | 395 | 406 | 419 | 439 | 0.0600 | 1088 | 1.215 | 99.36 | 36.50 | 1 | 0.0386 | 244 | 0.0018 | 29.68 | 6.658 | 0.2214 | 148564.0 | 58400000 | 23200000000 | 9350000000000 | 0.4200 | 0.2268 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0033 | 0.0005 | 0.0198 | 0.0108 | 0.0385 | 0.0209 | 0.0480 | 0.0104 | 0.0811 | 0.0223 | 0.8084 | 0.9351 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0015 | 0.0005 | 0.0136 | 0.0108 | 0.0260 | 0.0209 | 0.0246 | 0.0104 | 0.0395 | 0.0223 | 0.8947 | 0.9351 | 0.0536 | 0.0000 | 0.0421 | 0.0000 | 0.0651 | 0.0000 | 0.1303 | 0.0000 | 0.1418 | 0.0000 | 0.2222 | 0.0000 | 0.1188 | 0.0000 | 0.1341 | 0.0000 | 0.0920 | 0.0000 | 0.0012 | 0.0049 | 0.0132 | 0.0292 | 0.0679 | 0.1075 | 0.1161 | 0.1588 | 0.5012 | 17 | 22 | 29 | 46 | 89 | 180 | 301 | 457 | 675 | 0.0295 | 57.83 | 5.943 | 0.4328 | 143927.0 | 117000000 | 112000000000 | 121000000000000 | 0.4463 | 0.1845 | 0.0546 | 0.0038 | 0.1914 | 0.0093 | 0.2906 | 0.1053 | 0.1701 | 0.1693 | 0.1184 | 0.2109 | 0.1042 | 0.1922 | 0.0475 | 0.1153 | 0.0156 | 0.0952 | 0.0078 | 0.0987 | 0.0001 | 0.0005 | 0.0011 | 0.0005 | 0.0034 | 0.0014 | 0.0108 | 0.0082 | 0.0532 | 0.0501 | 0.0872 | 0.0742 | 0.0606 | 0.0519 | 0.0872 | 0.0802 | 0.6963 | 0.7330 | 0.0005 | 0.0004 | 0.0021 | 0.0008 | 0.0042 | 0.0052 | 0.0150 | 0.0185 | 0.0656 | 0.0707 | 0.1028 | 0.1137 | 0.0807 | 0.0882 | 0.1081 | 0.1140 | 0.6208 | 0.5885 | 0.0002 | 0.0016 | 0.0046 | 0.0142 | 0.0602 | 0.0943 | 0.0678 | 0.0986 | 0.6586 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 996 | 371 | | 11089 | 20661 | 128.1 | 44.85 | 133.68 | 162.62 | 71 | 85 | 99 | 115 | 127 | 138 | 151 | 166 | 188 | 0.0798 | 1648 | 0.895 | 64.56 | 20.03 | 5 | 0.0157 | 174 | 0.0018 | 12.86 | 6.621 | 0.3191 | 18415.0 | 2900000 | 491000000 | 88000000000 | 0.4803 | 0.1576 | 0.0011 | 0.0006 | 0.0045 | 0.0016 | 0.0117 | 0.0035 | 0.0293 | 0.0084 | 0.0819 | 0.0379 | 0.1359 | 0.0583 | 0.1247 | 0.0644 | 0.1531 | 0.0930 | 0.4578 | 0.7323 | 0.0005 | 0.0003 | 0.0015 | 0.0006 | 0.0021 | 0.0017 | 0.0042 | 0.0037 | 0.0222 | 0.0194 | 0.0351 | 0.0255 | 0.0297 | 0.0272 | 0.0482 | 0.0398 | 0.8566 | 0.8816 | 0.0019 | 0.0046 | 0.0038 | 0.0046 | 0.0118 | 0.0178 | 0.0290 | 0.0462 | 0.0667 | 0.1116 | 0.1062 | 0.1155 | 0.0871 | 0.1063 | 0.1161 | 0.1373 | 0.5774 | 0.4561 | 0.0020 | 0.0040 | 0.0047 | 0.0125 | 0.0360 | 0.0599 | 0.0579 | 0.0894 | 0.7335 | 14 | 19 | 29 | 48 | 73 | 107 | 151 | 215 | 335 | 0.0199 | 22.80 | 5.542 | 0.4729 | 44312.1 | 23700000 | 16900000000 | 14500000000000 | 0.5483 | 0.1240 | 0.0154 | 0.0018 | 0.0718 | 0.0095 | 0.1644 | 0.0294 | 0.1714 | 0.0676 | 0.1731 | 0.1375 | 0.1619 | 0.1889 | 0.0967 | 0.1393 | 0.0751 | 0.1444 | 0.0702 | 0.2815 | 0.0008 | 0.0004 | 0.0017 | 0.0019 | 0.0035 | 0.0031 | 0.0174 | 0.0115 | 0.0505 | 0.0433 | 0.0835 | 0.0717 | 0.0604 | 0.0502 | 0.0852 | 0.0807 | 0.6968 | 0.7370 | 0.0015 | 0.0010 | 0.0051 | 0.0020 | 0.0056 | 0.0073 | 0.0197 | 0.0275 | 0.0672 | 0.0761 | 0.1032 | 0.1073 | 0.0716 | 0.0804 | 0.1082 | 0.1177 | 0.6178 | 0.5806 | 0.0010 | 0.0039 | 0.0055 | 0.0211 | 0.0524 | 0.0978 | 0.0670 | 0.0986 | 0.6527 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 976 | 862 | | 8371 | 10040 | 119.6 | 44.92 | 155.74 | 155.70 | 66 | 82 | 94 | 104 | 115 | 126 | 139 | 155 | 180 | 0.1011 | 1015 | 0.966 | 89.94 | 27.51 | 4 | 0.0288 | 241 | 0.0007 | 62.88 | 7.556 | 0.1767 | 16326.4 | 2490000 | 417000000 | 75800000000 | 0.4543 | 0.2049 | 0.0006 | 0.0000 | 0.0058 | 0.0003 | 0.0252 | 0.0021 | 0.0659 | 0.0106 | 0.1494 | 0.0457 | 0.1923 | 0.0930 | 0.1593 | 0.0951 | 0.1636 | 0.1235 | 0.2379 | 0.6298 | 0.0002 | 0.0000 | 0.0010 | 0.0001 | 0.0033 | 0.0005 | 0.0121 | 0.0036 | 0.0500 | 0.0240 | 0.0668 | 0.0448 | 0.0596 | 0.0367 | 0.0870 | 0.0539 | 0.7200 | 0.8364 | 0.0009 | 0.0034 | 0.0035 | 0.0017 | 0.0132 | 0.0299 | 0.0475 | 0.0708 | 0.1174 | 0.1561 | 0.1500 | 0.1698 | 0.1047 | 0.0998 | 0.1341 | 0.1519 | 0.4288 | 0.3166 | 0.0011 | 0.0037 | 0.0045 | 0.0250 | 0.0677 | 0.1195 | 0.0937 | 0.1219 | 0.5629 | 15 | 25 | 47 | 74 | 107 | 150 | 200 | 260 | 359 | 0.0159 | 26.97 | 5.856 | 0.3967 | 48494.1 | 21800000 | 12600000000 | 8830000000000 | 0.5977 | 0.0835 | 0.0353 | 0.0018 | 0.1603 | 0.0185 | 0.3052 | 0.0912 | 0.1733 | 0.1119 | 0.1411 | 0.1866 | 0.1005 | 0.2165 | 0.0460 | 0.1263 | 0.0314 | 0.1278 | 0.0069 | 0.1193 | 0.0002 | 0.0006 | 0.0011 | 0.0009 | 0.0055 | 0.0039 | 0.0196 | 0.0131 | 0.0627 | 0.0586 | 0.1262 | 0.1037 | 0.0878 | 0.0736 | 0.1216 | 0.1085 | 0.5754 | 0.6371 | 0.0006 | 0.0030 | 0.0043 | 0.0059 | 0.0101 | 0.0111 | 0.0336 | 0.0392 | 0.0864 | 0.1103 | 0.1639 | 0.1799 | 0.1184 | 0.1136 | 0.1334 | 0.1358 | 0.4495 | 0.4012 | 0.0008 | 0.0015 | 0.0069 | 0.0240 | 0.0769 | 0.1428 | 0.0979 | 0.1329 | 0.5164 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 591 | 329 | | 4059 | 4051 | 149.9 | 44.98 | 152.81 | 103.02 | 95 | 110 | 122 | 134 | 145 | 156 | 170 | 185 | 211 | 0.1824 | 739 | 0.920 | 69.64 | 26.25 | 1 | 0.0493 | 200 | 0.0013 | 36.19 | 6.869 | 0.2026 | 24493.5 | 4340000 | 829000000 | 169000000000 | 0.4381 | 0.2179 | 0.0010 | 0.0000 | 0.0020 | 0.0006 | 0.0237 | 0.0015 | 0.0622 | 0.0050 | 0.1475 | 0.0394 | 0.2153 | 0.0977 | 0.1769 | 0.0924 | 0.1511 | 0.1146 | 0.2203 | 0.6487 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0034 | 0.0008 | 0.0127 | 0.0016 | 0.0491 | 0.0255 | 0.1050 | 0.0516 | 0.0769 | 0.0408 | 0.0978 | 0.0574 | 0.6543 | 0.8222 | 0.0021 | 0.0071 | 0.0032 | 0.0095 | 0.0203 | 0.0309 | 0.0664 | 0.1164 | 0.1756 | 0.2019 | 0.1874 | 0.2233 | 0.1113 | 0.0879 | 0.1520 | 0.1164 | 0.2816 | 0.2067 | 0.0000 | 0.0011 | 0.0070 | 0.0316 | 0.1002 | 0.1522 | 0.0997 | 0.1442 | 0.4641 | 38 | 60 | 81 | 105 | 133 | 164 | 196 | 234 | 296 | 0.0029 | 26.57 | 6.397 | 0.3265 | 33960.4 | 9530000 | 3160000000 | 1200000000000 | 0.5229 | 0.1431 | 0.0171 | 0.0012 | 0.1148 | 0.0116 | 0.2369 | 0.0408 | 0.1685 | 0.0987 | 0.1709 | 0.1749 | 0.1258 | 0.2108 | 0.0733 | 0.1475 | 0.0635 | 0.1511 | 0.0293 | 0.1633 | 0.0000 | 0.0004 | 0.0037 | 0.0011 | 0.0064 | 0.0053 | 0.0320 | 0.0224 | 0.0859 | 0.0765 | 0.1293 | 0.1057 | 0.1028 | 0.0856 | 0.1325 | 0.1118 | 0.5073 | 0.5911 | 0.0037 | 0.0060 | 0.0073 | 0.0140 | 0.0190 | 0.0351 | 0.0467 | 0.0852 | 0.1402 | 0.1543 | 0.1958 | 0.1944 | 0.1242 | 0.1333 | 0.1570 | 0.1353 | 0.3061 | 0.2425 | 0.0017 | 0.0040 | 0.0090 | 0.0384 | 0.0942 | 0.1738 | 0.1196 | 0.1535 | 0.4058 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 834 | 433 | | 10028 | 23515 | 170.4 | 45.07 | 251.81 | 223.41 | 116 | 130 | 142 | 154 | 167 | 180 | 195 | 212 | 231 | 0.0643 | 1511 | 0.433 | 138.81 | 20.40 | 4 | 0.0343 | 344 | 0.0006 | 58.13 | 7.696 | 0.1518 | 31076.2 | 6010000 | 1230000000 | 261000000000 | 0.4626 | 0.2012 | 0.0014 | 0.0001 | 0.0014 | 0.0000 | 0.0051 | 0.0010 | 0.0350 | 0.0070 | 0.1108 | 0.0315 | 0.1699 | 0.0658 | 0.1503 | 0.0658 | 0.1738 | 0.0971 | 0.3522 | 0.7316 | 0.0008 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0007 | 0.0127 | 0.0044 | 0.0411 | 0.0206 | 0.0636 | 0.0401 | 0.0541 | 0.0301 | 0.0732 | 0.0469 | 0.7527 | 0.8573 | 0.0016 | 0.0064 | 0.0036 | 0.0242 | 0.0121 | 0.0382 | 0.0395 | 0.1057 | 0.0999 | 0.1643 | 0.1386 | 0.1771 | 0.1185 | 0.1414 | 0.1350 | 0.1210 | 0.4512 | 0.2217 | 0.0013 | 0.0027 | 0.0055 | 0.0224 | 0.0554 | 0.0952 | 0.0829 | 0.1036 | 0.6310 | 27 | 65 | 104 | 142 | 188 | 246 | 318 | 410 | 550 | 0.0043 | 51.61 | 6.756 | 0.3199 | 113315.0 | 70500000 | 54700000000 | 49800000000000 | 0.5106 | 0.1551 | 0.0197 | 0.0009 | 0.0972 | 0.0050 | 0.2185 | 0.0351 | 0.1851 | 0.0833 | 0.1744 | 0.1635 | 0.1413 | 0.2193 | 0.0821 | 0.1599 | 0.0479 | 0.1407 | 0.0337 | 0.1922 | 0.0004 | 0.0003 | 0.0007 | 0.0007 | 0.0030 | 0.0032 | 0.0179 | 0.0117 | 0.0615 | 0.0449 | 0.0961 | 0.0795 | 0.0799 | 0.0637 | 0.0995 | 0.0868 | 0.6409 | 0.7092 | 0.0008 | 0.0013 | 0.0027 | 0.0038 | 0.0078 | 0.0110 | 0.0324 | 0.0428 | 0.0867 | 0.1042 | 0.1373 | 0.1566 | 0.0965 | 0.1074 | 0.1356 | 0.1445 | 0.5003 | 0.4284 | 0.0004 | 0.0017 | 0.0054 | 0.0273 | 0.0740 | 0.1165 | 0.0851 | 0.1169 | 0.5726 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1013 | 776 | | 4132 | 4149 | 163.6 | 45.21 | 162.20 | 159.12 | 116 | 127 | 136 | 145 | 155 | 166 | 178 | 197 | 224 | 0.1347 | 559 | 1.127 | 94.07 | 29.83 | 1 | 0.0549 | 227 | 0.0016 | 35.59 | 6.765 | 0.2144 | 28795.0 | 5490000 | 1140000000 | 256000000000 | 0.3736 | 0.2711 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0097 | 0.0000 | 0.0313 | 0.0016 | 0.1031 | 0.0289 | 0.1793 | 0.0586 | 0.1696 | 0.0559 | 0.1608 | 0.0805 | 0.3449 | 0.7744 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0000 | 0.0126 | 0.0012 | 0.0426 | 0.0173 | 0.0765 | 0.0318 | 0.0726 | 0.0202 | 0.0833 | 0.0333 | 0.7089 | 0.8961 | 0.0012 | 0.0057 | 0.0060 | 0.0028 | 0.0193 | 0.0342 | 0.0712 | 0.1026 | 0.1351 | 0.1852 | 0.1689 | 0.1538 | 0.1074 | 0.1254 | 0.1544 | 0.1282 | 0.3366 | 0.2621 | 0.0006 | 0.0029 | 0.0081 | 0.0400 | 0.0737 | 0.1398 | 0.0986 | 0.1119 | 0.5244 | 19 | 39 | 59 | 79 | 105 | 140 | 187 | 267 | 405 | 0.0058 | 51.95 | 6.395 | 0.3274 | 51621.9 | 23000000 | 12200000000 | 7280000000000 | 0.4555 | 0.1933 | 0.0214 | 0.0008 | 0.1246 | 0.0084 | 0.2206 | 0.0489 | 0.1851 | 0.1281 | 0.1495 | 0.1778 | 0.1388 | 0.1912 | 0.0747 | 0.1272 | 0.0534 | 0.1348 | 0.0320 | 0.1828 | 0.0006 | 0.0000 | 0.0011 | 0.0036 | 0.0034 | 0.0027 | 0.0238 | 0.0173 | 0.0747 | 0.0600 | 0.1065 | 0.1055 | 0.0821 | 0.0673 | 0.1121 | 0.1014 | 0.5957 | 0.6421 | 0.0017 | 0.0000 | 0.0033 | 0.0040 | 0.0083 | 0.0049 | 0.0282 | 0.0346 | 0.0698 | 0.0949 | 0.1412 | 0.1215 | 0.0947 | 0.1057 | 0.1204 | 0.1364 | 0.5324 | 0.4980 | 0.0007 | 0.0034 | 0.0103 | 0.0248 | 0.0765 | 0.1254 | 0.0827 | 0.1158 | 0.5603 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 532 | 259 | | 3712 | 5457 | 168.2 | 45.22 | 152.55 | 98.18 | 118 | 130 | 141 | 151 | 161 | 171 | 183 | 199 | 228 | 0.1063 | 580 | 0.874 | 81.88 | 22.63 | 1 | 0.0568 | 211 | 0.0014 | 50.43 | 6.887 | 0.1876 | 30320.2 | 5890000 | 1230000000 | 278000000000 | 0.4069 | 0.2403 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0062 | 0.0000 | 0.0317 | 0.0030 | 0.1075 | 0.0290 | 0.1833 | 0.0635 | 0.1611 | 0.0635 | 0.1701 | 0.0982 | 0.3382 | 0.7428 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0000 | 0.0092 | 0.0008 | 0.0427 | 0.0178 | 0.0828 | 0.0324 | 0.0732 | 0.0250 | 0.0970 | 0.0453 | 0.6925 | 0.8788 | 0.0043 | 0.0098 | 0.0085 | 0.0131 | 0.0199 | 0.0359 | 0.0641 | 0.1242 | 0.1709 | 0.1797 | 0.1966 | 0.2222 | 0.1040 | 0.1307 | 0.1496 | 0.1242 | 0.2821 | 0.1601 | 0.0006 | 0.0044 | 0.0087 | 0.0355 | 0.1060 | 0.1390 | 0.1228 | 0.1465 | 0.4364 | 47 | 67 | 88 | 108 | 132 | 156 | 187 | 227 | 288 | 0.0026 | 30.72 | 6.456 | 0.2975 | 32908.8 | 9090000 | 3020000000 | 1160000000000 | 0.5362 | 0.1215 | 0.0115 | 0.0020 | 0.0516 | 0.0061 | 0.1491 | 0.0235 | 0.1589 | 0.0465 | 0.1851 | 0.1266 | 0.1720 | 0.1828 | 0.1261 | 0.1517 | 0.0827 | 0.1485 | 0.0631 | 0.3123 | 0.0007 | 0.0008 | 0.0017 | 0.0011 | 0.0079 | 0.0030 | 0.0171 | 0.0129 | 0.0690 | 0.0487 | 0.1097 | 0.0810 | 0.0861 | 0.0732 | 0.1168 | 0.1001 | 0.5910 | 0.6792 | 0.0012 | 0.0008 | 0.0059 | 0.0096 | 0.0152 | 0.0241 | 0.0463 | 0.0643 | 0.1032 | 0.1230 | 0.1641 | 0.1873 | 0.1208 | 0.1270 | 0.1319 | 0.1367 | 0.4115 | 0.3272 | 0.0018 | 0.0009 | 0.0066 | 0.0331 | 0.0888 | 0.1391 | 0.1069 | 0.1343 | 0.4885 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1018 | 588 | | 3811 | 2194 | 152.8 | 45.25 | 165.29 | 120.38 | 109 | 118 | 126 | 134 | 142 | 151 | 164 | 180 | 214 | 0.2334 | 512 | 1.053 | 95.88 | 21.84 | 1 | 0.0559 | 213 | 0.0019 | 30.81 | 6.595 | 0.2281 | 25408.3 | 4650000 | 946000000 | 214000000000 | 0.3988 | 0.2432 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0000 | 0.0266 | 0.0015 | 0.1000 | 0.0318 | 0.1613 | 0.0588 | 0.1678 | 0.0558 | 0.1730 | 0.0780 | 0.3604 | 0.7742 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0053 | 0.0000 | 0.0145 | 0.0008 | 0.0469 | 0.0184 | 0.0800 | 0.0301 | 0.0793 | 0.0235 | 0.0959 | 0.0379 | 0.6781 | 0.8893 | 0.0014 | 0.0000 | 0.0201 | 0.0000 | 0.0086 | 0.0026 | 0.0459 | 0.0741 | 0.1119 | 0.1481 | 0.1607 | 0.1984 | 0.0947 | 0.1085 | 0.1349 | 0.1614 | 0.4218 | 0.3069 | 0.0040 | 0.0094 | 0.0101 | 0.0330 | 0.0808 | 0.1359 | 0.0969 | 0.1151 | 0.5148 | 45 | 64 | 85 | 108 | 136 | 167 | 200 | 252 | 322 | 0.0021 | 74.42 | 6.577 | 0.2161 | 41805.4 | 14100000 | 5770000000 | 2690000000000 | 0.5152 | 0.1357 | 0.0346 | 0.0000 | 0.1364 | 0.0171 | 0.2165 | 0.0798 | 0.1667 | 0.1277 | 0.1688 | 0.1631 | 0.1190 | 0.1836 | 0.0909 | 0.1072 | 0.0455 | 0.1482 | 0.0216 | 0.1733 | 0.0000 | 0.0000 | 0.0009 | 0.0014 | 0.0097 | 0.0043 | 0.0292 | 0.0264 | 0.1205 | 0.0785 | 0.1763 | 0.1527 | 0.1045 | 0.0935 | 0.1523 | 0.1456 | 0.4066 | 0.4975 | 0.0030 | 0.0057 | 0.0045 | 0.0038 | 0.0285 | 0.0286 | 0.0615 | 0.0782 | 0.1529 | 0.1794 | 0.2144 | 0.2271 | 0.1229 | 0.1355 | 0.1439 | 0.1240 | 0.2684 | 0.2176 | 0.0011 | 0.0034 | 0.0202 | 0.0506 | 0.1406 | 0.1755 | 0.1260 | 0.1586 | 0.3240 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 538 | 522 | | 10143 | 24967 | 137.2 | 45.41 | 180.80 | 230.55 | 91 | 101 | 110 | 118 | 127 | 137 | 150 | 167 | 198 | 0.0470 | 1173 | 0.400 | 194.49 | 33.54 | 5 | 0.0550 | 558 | 0.0019 | 26.27 | 6.724 | 0.2500 | 20883.8 | 3560000 | 679000000 | 145000000000 | 0.4664 | 0.1883 | 0.0012 | 0.0001 | 0.0036 | 0.0001 | 0.0091 | 0.0012 | 0.0383 | 0.0057 | 0.1113 | 0.0305 | 0.1764 | 0.0645 | 0.1603 | 0.0659 | 0.1744 | 0.0958 | 0.3255 | 0.7361 | 0.0007 | 0.0001 | 0.0021 | 0.0001 | 0.0034 | 0.0007 | 0.0142 | 0.0028 | 0.0411 | 0.0161 | 0.0774 | 0.0311 | 0.0693 | 0.0286 | 0.0908 | 0.0446 | 0.7011 | 0.8759 | 0.0032 | 0.0009 | 0.0055 | 0.0026 | 0.0120 | 0.0205 | 0.0443 | 0.0759 | 0.1061 | 0.1253 | 0.1513 | 0.1748 | 0.1070 | 0.1228 | 0.1402 | 0.1313 | 0.4304 | 0.3461 | 0.0022 | 0.0049 | 0.0080 | 0.0279 | 0.0670 | 0.1061 | 0.0989 | 0.1234 | 0.5616 | 11 | 13 | 17 | 26 | 61 | 137 | 226 | 346 | 527 | 0.0541 | 38.24 | 5.495 | 0.4994 | 85842.1 | 54700000 | 40900000000 | 34200000000000 | 0.5806 | 0.1163 | 0.0514 | 0.0037 | 0.1686 | 0.0204 | 0.2152 | 0.1049 | 0.1551 | 0.1368 | 0.1378 | 0.1772 | 0.1287 | 0.1802 | 0.0730 | 0.1206 | 0.0476 | 0.1111 | 0.0226 | 0.1450 | 0.0004 | 0.0003 | 0.0008 | 0.0002 | 0.0017 | 0.0011 | 0.0086 | 0.0061 | 0.0487 | 0.0419 | 0.0930 | 0.0753 | 0.0691 | 0.0562 | 0.0965 | 0.0845 | 0.6812 | 0.7344 | 0.0005 | 0.0003 | 0.0014 | 0.0013 | 0.0031 | 0.0041 | 0.0161 | 0.0199 | 0.0661 | 0.0733 | 0.1165 | 0.1280 | 0.0805 | 0.0882 | 0.1160 | 0.1179 | 0.5998 | 0.5670 | 0.0002 | 0.0007 | 0.0022 | 0.0128 | 0.0574 | 0.1049 | 0.0737 | 0.1099 | 0.6383 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 819 | 837 | | 4077 | 7402 | 164.0 | 45.49 | 281.51 | 208.60 | 106 | 126 | 139 | 150 | 161 | 172 | 185 | 201 | 225 | 0.0809 | 599 | 0.666 | 68.59 | 22.56 | 2 | 0.0518 | 211 | 0.0013 | 30.19 | 6.879 | 0.2104 | 28976.0 | 5470000 | 1100000000 | 232000000000 | 0.4785 | 0.1795 | 0.0028 | 0.0000 | 0.0032 | 0.0006 | 0.0065 | 0.0020 | 0.0341 | 0.0061 | 0.1138 | 0.0314 | 0.1876 | 0.0802 | 0.1618 | 0.0709 | 0.1834 | 0.0994 | 0.3069 | 0.7095 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0019 | 0.0005 | 0.0081 | 0.0026 | 0.0430 | 0.0195 | 0.0783 | 0.0445 | 0.0608 | 0.0306 | 0.0935 | 0.0458 | 0.7126 | 0.8562 | 0.0043 | 0.0113 | 0.0185 | 0.0226 | 0.0120 | 0.0452 | 0.0663 | 0.1271 | 0.1261 | 0.1582 | 0.1815 | 0.2345 | 0.1239 | 0.1356 | 0.1424 | 0.0989 | 0.3250 | 0.1667 | 0.0015 | 0.0021 | 0.0072 | 0.0355 | 0.0762 | 0.1340 | 0.1061 | 0.1175 | 0.5198 | 41 | 86 | 136 | 190 | 247 | 308 | 370 | 448 | 564 | 0.0018 | 128.90 | 7.431 | 0.1991 | 122752.0 | 67400000 | 43400000000 | 31600000000000 | 0.5494 | 0.1250 | 0.0218 | 0.0004 | 0.1102 | 0.0047 | 0.2408 | 0.0505 | 0.1748 | 0.0920 | 0.1769 | 0.1749 | 0.1363 | 0.2080 | 0.0798 | 0.1531 | 0.0428 | 0.1385 | 0.0167 | 0.1778 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0011 | 0.0151 | 0.0089 | 0.0627 | 0.0498 | 0.1204 | 0.0924 | 0.0929 | 0.0759 | 0.1327 | 0.1043 | 0.5715 | 0.6676 | 0.0000 | 0.0020 | 0.0042 | 0.0036 | 0.0096 | 0.0137 | 0.0301 | 0.0493 | 0.1131 | 0.1301 | 0.1521 | 0.1876 | 0.1212 | 0.1256 | 0.1613 | 0.1520 | 0.4083 | 0.3360 | 0.0015 | 0.0024 | 0.0049 | 0.0182 | 0.0809 | 0.1469 | 0.1031 | 0.1338 | 0.5082 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 293 | 128 | | 4381 | 3891 | 142.2 | 45.53 | 116.54 | 68.03 | 93 | 105 | 115 | 124 | 134 | 144 | 156 | 174 | 206 | 0.1773 | 690 | 1.154 | 92.96 | 30.48 | 1 | 0.0539 | 236 | 0.0014 | 45.81 | 6.878 | 0.1869 | 22305.5 | 3870000 | 744000000 | 158000000000 | 0.4152 | 0.2335 | 0.0000 | 0.0000 | 0.0045 | 0.0003 | 0.0186 | 0.0022 | 0.0626 | 0.0091 | 0.1392 | 0.0365 | 0.1946 | 0.0890 | 0.1642 | 0.0862 | 0.1655 | 0.1307 | 0.2508 | 0.6460 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0038 | 0.0010 | 0.0190 | 0.0034 | 0.0514 | 0.0191 | 0.0936 | 0.0528 | 0.0787 | 0.0396 | 0.1148 | 0.0671 | 0.6372 | 0.8169 | 0.0021 | 0.0099 | 0.0063 | 0.0079 | 0.0264 | 0.0258 | 0.0738 | 0.0813 | 0.1276 | 0.1488 | 0.1762 | 0.1925 | 0.1171 | 0.1310 | 0.1403 | 0.1587 | 0.3302 | 0.2440 | 0.0016 | 0.0054 | 0.0136 | 0.0490 | 0.1017 | 0.1447 | 0.1181 | 0.1371 | 0.4287 | 38 | 55 | 71 | 88 | 106 | 126 | 145 | 172 | 209 | 0.0023 | 29.24 | 6.422 | 0.2512 | 18208.7 | 3510000 | 804000000 | 216000000000 | 0.4985 | 0.1471 | 0.0212 | 0.0005 | 0.0945 | 0.0070 | 0.1741 | 0.0289 | 0.1656 | 0.0690 | 0.1975 | 0.1573 | 0.1592 | 0.1669 | 0.0902 | 0.1493 | 0.0637 | 0.1728 | 0.0340 | 0.2483 | 0.0018 | 0.0000 | 0.0041 | 0.0011 | 0.0091 | 0.0040 | 0.0279 | 0.0190 | 0.0741 | 0.0623 | 0.1189 | 0.0845 | 0.1006 | 0.0758 | 0.1161 | 0.1217 | 0.5473 | 0.6316 | 0.0048 | 0.0023 | 0.0088 | 0.0137 | 0.0201 | 0.0286 | 0.0530 | 0.0766 | 0.1349 | 0.1646 | 0.1743 | 0.1737 | 0.1245 | 0.1234 | 0.1414 | 0.1349 | 0.3382 | 0.2823 | 0.0006 | 0.0069 | 0.0103 | 0.0322 | 0.0925 | 0.1516 | 0.1040 | 0.1338 | 0.4681 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 127 | 580 | | 4890 | 10021 | 167.2 | 45.62 | 128.15 | 116.75 | 114 | 127 | 138 | 149 | 161 | 173 | 187 | 205 | 230 | 0.0875 | 877 | 0.739 | 103.47 | 30.61 | 1 | 0.0599 | 293 | 0.0011 | 49.25 | 7.043 | 0.1864 | 30027.2 | 5780000 | 1190000000 | 261000000000 | 0.4177 | 0.2308 | 0.0016 | 0.0002 | 0.0054 | 0.0005 | 0.0140 | 0.0014 | 0.0490 | 0.0063 | 0.1319 | 0.0305 | 0.2074 | 0.0675 | 0.1903 | 0.0781 | 0.1763 | 0.1142 | 0.2241 | 0.7013 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0025 | 0.0004 | 0.0156 | 0.0008 | 0.0542 | 0.0191 | 0.0826 | 0.0342 | 0.0846 | 0.0354 | 0.1043 | 0.0562 | 0.6544 | 0.8538 | 0.0018 | 0.0045 | 0.0120 | 0.0112 | 0.0221 | 0.0604 | 0.0766 | 0.1029 | 0.1485 | 0.2215 | 0.1845 | 0.1879 | 0.1236 | 0.1342 | 0.1494 | 0.1409 | 0.2814 | 0.1365 | 0.0005 | 0.0023 | 0.0104 | 0.0379 | 0.0974 | 0.1312 | 0.1028 | 0.1398 | 0.4779 | 18 | 32 | 51 | 70 | 93 | 120 | 156 | 205 | 286 | 0.0036 | 60.89 | 6.753 | 0.2645 | 30050.3 | 9900000 | 4030000000 | 1890000000000 | 0.5421 | 0.1392 | 0.0340 | 0.0028 | 0.1454 | 0.0145 | 0.2293 | 0.0767 | 0.1787 | 0.1127 | 0.1537 | 0.1622 | 0.1192 | 0.1926 | 0.0769 | 0.1335 | 0.0429 | 0.1338 | 0.0199 | 0.1711 | 0.0004 | 0.0007 | 0.0017 | 0.0025 | 0.0043 | 0.0030 | 0.0229 | 0.0167 | 0.0712 | 0.0549 | 0.1280 | 0.1023 | 0.1062 | 0.0776 | 0.1235 | 0.1156 | 0.5418 | 0.6267 | 0.0023 | 0.0008 | 0.0052 | 0.0076 | 0.0124 | 0.0139 | 0.0322 | 0.0458 | 0.0970 | 0.1178 | 0.1758 | 0.1715 | 0.1120 | 0.1126 | 0.1143 | 0.1182 | 0.4489 | 0.4119 | 0.0005 | 0.0034 | 0.0093 | 0.0276 | 0.0928 | 0.1477 | 0.1082 | 0.1318 | 0.4785 |