High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 898 | 503 | | 7597 | 15942 | 143.4 | 27.73 | 173.50 | 120.68 | 110 | 119 | 126 | 132 | 140 | 148 | 157 | 168 | 183 | 0.0661 | 1053 | 1.190 | 84.90 | 37.16 | 1 | 0.0309 | 235 | 0.0025 | 15.67 | 6.274 | 0.2752 | 21329.9 | 3290000 | 525000000 | 86500000000 | 0.4372 | 0.2078 | 0.0006 | 0.0000 | 0.0010 | 0.0000 | 0.0046 | 0.0001 | 0.0191 | 0.0007 | 0.0570 | 0.0136 | 0.1188 | 0.0324 | 0.1394 | 0.0300 | 0.1797 | 0.0527 | 0.4799 | 0.8705 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0096 | 0.0000 | 0.0278 | 0.0107 | 0.0488 | 0.0198 | 0.0578 | 0.0112 | 0.0842 | 0.0195 | 0.7694 | 0.9388 | 0.0070 | 0.0409 | 0.0141 | 0.0591 | 0.0273 | 0.0955 | 0.0703 | 0.1955 | 0.1453 | 0.2727 | 0.1641 | 0.1500 | 0.1258 | 0.0545 | 0.1516 | 0.0864 | 0.2945 | 0.0455 | 0.0017 | 0.0034 | 0.0095 | 0.0337 | 0.0685 | 0.1129 | 0.1067 | 0.1314 | 0.5322 | 41 | 69 | 95 | 120 | 148 | 179 | 215 | 264 | 340 | 0.0019 | 36.17 | 6.887 | 0.2809 | 44665.2 | 14900000 | 5940000000 | 2730000000000 | 0.4612 | 0.1723 | 0.0167 | 0.0012 | 0.0841 | 0.0062 | 0.1709 | 0.0303 | 0.1727 | 0.0682 | 0.1885 | 0.1425 | 0.1471 | 0.1913 | 0.0984 | 0.1576 | 0.0707 | 0.1542 | 0.0507 | 0.2485 | 0.0012 | 0.0005 | 0.0036 | 0.0018 | 0.0077 | 0.0047 | 0.0185 | 0.0109 | 0.0606 | 0.0516 | 0.1144 | 0.0972 | 0.0887 | 0.0746 | 0.1158 | 0.0983 | 0.5895 | 0.6604 | 0.0006 | 0.0021 | 0.0065 | 0.0130 | 0.0156 | 0.0199 | 0.0449 | 0.0483 | 0.1050 | 0.1174 | 0.1463 | 0.1612 | 0.1156 | 0.1174 | 0.1360 | 0.1333 | 0.4295 | 0.3874 | 0.0013 | 0.0034 | 0.0091 | 0.0235 | 0.0795 | 0.1362 | 0.1016 | 0.1281 | 0.5171 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 845 | 391 | | 8714 | 28501 | 282.2 | 64.28 | 121.16 | 121.03 | 206 | 227 | 243 | 259 | 276 | 293 | 313 | 334 | 368 | 0.0454 | 1293 | 1.148 | 102.08 | 30.46 | 1 | 0.0270 | 235 | 0.0023 | 14.79 | 6.394 | 0.2854 | 83742.3 | 26100000 | 8530000000 | 2910000000000 | 0.4516 | 0.1999 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0048 | 0.0004 | 0.0140 | 0.0014 | 0.0658 | 0.0182 | 0.1361 | 0.0403 | 0.1469 | 0.0472 | 0.1796 | 0.0612 | 0.4515 | 0.8313 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0002 | 0.0057 | 0.0007 | 0.0319 | 0.0118 | 0.0595 | 0.0218 | 0.0612 | 0.0237 | 0.0824 | 0.0326 | 0.7570 | 0.9091 | 0.0044 | 0.0000 | 0.0062 | 0.0143 | 0.0187 | 0.0531 | 0.0704 | 0.0755 | 0.1172 | 0.1633 | 0.1509 | 0.2286 | 0.1010 | 0.0857 | 0.1415 | 0.1429 | 0.3897 | 0.2367 | 0.0005 | 0.0007 | 0.0074 | 0.0253 | 0.0763 | 0.1144 | 0.0817 | 0.1207 | 0.5730 | 16 | 28 | 45 | 64 | 86 | 111 | 142 | 189 | 270 | 0.0173 | 10.15 | 5.255 | 0.4896 | 29326.3 | 11100000 | 5770000000 | 3740000000000 | 0.5092 | 0.1670 | 0.0151 | 0.0015 | 0.0740 | 0.0061 | 0.1650 | 0.0287 | 0.1715 | 0.0720 | 0.1760 | 0.1555 | 0.1560 | 0.1872 | 0.1115 | 0.1505 | 0.0848 | 0.1481 | 0.0462 | 0.2505 | 0.0002 | 0.0005 | 0.0014 | 0.0011 | 0.0052 | 0.0033 | 0.0204 | 0.0126 | 0.0607 | 0.0488 | 0.0975 | 0.0843 | 0.0811 | 0.0687 | 0.1062 | 0.0968 | 0.6273 | 0.6839 | 0.0018 | 0.0015 | 0.0029 | 0.0027 | 0.0062 | 0.0087 | 0.0255 | 0.0332 | 0.0815 | 0.0912 | 0.1277 | 0.1335 | 0.0916 | 0.0982 | 0.1235 | 0.1301 | 0.5393 | 0.5010 | 0.0013 | 0.0021 | 0.0052 | 0.0239 | 0.0719 | 0.1113 | 0.0898 | 0.1163 | 0.5781 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1208 | 205 | | 6928 | 22071 | 341.7 | 78.65 | 108.42 | 121.55 | 242 | 273 | 297 | 318 | 338 | 358 | 381 | 406 | 444 | 0.0464 | 1025 | 0.821 | 127.02 | 32.56 | 1 | 0.0485 | 336 | 0.0010 | 44.29 | 7.174 | 0.1864 | 122938.0 | 46400000 | 18300000000 | 7530000000000 | 0.4442 | 0.2150 | 0.0005 | 0.0000 | 0.0009 | 0.0002 | 0.0054 | 0.0000 | 0.0289 | 0.0006 | 0.0774 | 0.0196 | 0.1548 | 0.0468 | 0.1496 | 0.0486 | 0.1733 | 0.0699 | 0.4092 | 0.8144 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0007 | 0.0000 | 0.0054 | 0.0001 | 0.0331 | 0.0134 | 0.0668 | 0.0319 | 0.0580 | 0.0246 | 0.0875 | 0.0358 | 0.7479 | 0.8940 | 0.0023 | 0.0124 | 0.0062 | 0.0155 | 0.0247 | 0.0310 | 0.0918 | 0.1455 | 0.1550 | 0.2012 | 0.1958 | 0.1827 | 0.1210 | 0.1022 | 0.1365 | 0.1269 | 0.2668 | 0.1827 | 0.0003 | 0.0015 | 0.0063 | 0.0271 | 0.0855 | 0.1353 | 0.1139 | 0.1317 | 0.4984 | 9 | 13 | 22 | 40 | 63 | 94 | 133 | 188 | 275 | 0.0306 | 13.52 | 5.344 | 0.4677 | 26526.8 | 9310000 | 4040000000 | 2020000000000 | 0.4133 | 0.2398 | 0.0339 | 0.0012 | 0.1396 | 0.0060 | 0.2401 | 0.0523 | 0.1953 | 0.1264 | 0.1400 | 0.1867 | 0.1291 | 0.2003 | 0.0747 | 0.1544 | 0.0331 | 0.1250 | 0.0141 | 0.1478 | 0.0006 | 0.0003 | 0.0014 | 0.0015 | 0.0028 | 0.0033 | 0.0161 | 0.0120 | 0.0537 | 0.0500 | 0.0941 | 0.0727 | 0.0729 | 0.0606 | 0.1043 | 0.0889 | 0.6540 | 0.7107 | 0.0007 | 0.0010 | 0.0031 | 0.0019 | 0.0047 | 0.0087 | 0.0232 | 0.0267 | 0.0849 | 0.0952 | 0.1181 | 0.1316 | 0.0860 | 0.0864 | 0.1223 | 0.1332 | 0.5570 | 0.5153 | 0.0002 | 0.0019 | 0.0039 | 0.0193 | 0.0666 | 0.1098 | 0.0796 | 0.1117 | 0.6070 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 156 | 594 | | 9080 | 15618 | 311.0 | 68.29 | 98.46 | 121.64 | 229 | 251 | 270 | 288 | 305 | 324 | 344 | 367 | 401 | 0.0788 | 1231 | 0.960 | 135.72 | 35.01 | 1 | 0.0352 | 320 | 0.0013 | 28.86 | 6.929 | 0.2122 | 101409.0 | 34600000 | 12300000000 | 4590000000000 | 0.4537 | 0.2035 | 0.0010 | 0.0000 | 0.0019 | 0.0001 | 0.0068 | 0.0009 | 0.0222 | 0.0025 | 0.0705 | 0.0167 | 0.1362 | 0.0410 | 0.1452 | 0.0416 | 0.1613 | 0.0640 | 0.4548 | 0.8331 | 0.0007 | 0.0000 | 0.0005 | 0.0000 | 0.0027 | 0.0006 | 0.0099 | 0.0020 | 0.0293 | 0.0115 | 0.0662 | 0.0283 | 0.0633 | 0.0223 | 0.0823 | 0.0364 | 0.7452 | 0.8989 | 0.0056 | 0.0027 | 0.0124 | 0.0318 | 0.0204 | 0.0637 | 0.0667 | 0.1141 | 0.1248 | 0.2042 | 0.1513 | 0.1485 | 0.1328 | 0.0716 | 0.1575 | 0.1300 | 0.3286 | 0.2334 | 0.0007 | 0.0030 | 0.0096 | 0.0287 | 0.0674 | 0.1168 | 0.1070 | 0.1261 | 0.5408 | 12 | 14 | 17 | 23 | 41 | 74 | 118 | 173 | 260 | 0.0390 | 25.52 | 5.297 | 0.4490 | 24490.2 | 9030000 | 4150000000 | 2200000000000 | 0.5460 | 0.1292 | 0.0690 | 0.0018 | 0.1999 | 0.0187 | 0.2994 | 0.1257 | 0.1613 | 0.1617 | 0.1323 | 0.2185 | 0.0814 | 0.1892 | 0.0378 | 0.1186 | 0.0145 | 0.0981 | 0.0044 | 0.0678 | 0.0002 | 0.0003 | 0.0012 | 0.0006 | 0.0031 | 0.0027 | 0.0151 | 0.0124 | 0.0691 | 0.0593 | 0.1090 | 0.0934 | 0.0785 | 0.0690 | 0.1141 | 0.1000 | 0.6096 | 0.6622 | 0.0011 | 0.0015 | 0.0023 | 0.0025 | 0.0079 | 0.0093 | 0.0234 | 0.0284 | 0.0888 | 0.0944 | 0.1239 | 0.1444 | 0.0960 | 0.0946 | 0.1298 | 0.1284 | 0.5268 | 0.4966 | 0.0002 | 0.0022 | 0.0039 | 0.0202 | 0.0788 | 0.1208 | 0.0884 | 0.1238 | 0.5618 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1162 | 503 | | 2529 | 2344 | 126.3 | 43.34 | 188.90 | 122.03 | 73 | 88 | 100 | 110 | 122 | 133 | 145 | 162 | 185 | 0.1950 | 457 | 0.720 | 84.38 | 20.03 | 1 | 0.0834 | 211 | 0.0009 | 89.32 | 7.225 | 0.1409 | 17828.9 | 2770000 | 469000000 | 85100000000 | 0.4531 | 0.1879 | 0.0000 | 0.0000 | 0.0045 | 0.0021 | 0.0334 | 0.0032 | 0.0885 | 0.0117 | 0.1554 | 0.0573 | 0.2069 | 0.1183 | 0.1527 | 0.1210 | 0.1509 | 0.1666 | 0.2078 | 0.5199 | 0.0000 | 0.0000 | 0.0006 | 0.0013 | 0.0023 | 0.0018 | 0.0153 | 0.0081 | 0.0512 | 0.0346 | 0.0904 | 0.0606 | 0.0745 | 0.0454 | 0.0944 | 0.0718 | 0.6714 | 0.7764 | 0.0031 | 0.0088 | 0.0077 | 0.0263 | 0.0153 | 0.0351 | 0.0537 | 0.0906 | 0.1503 | 0.1579 | 0.1656 | 0.1813 | 0.1012 | 0.0906 | 0.1518 | 0.1579 | 0.3512 | 0.2515 | 0.0000 | 0.0009 | 0.0043 | 0.0282 | 0.1059 | 0.1443 | 0.1059 | 0.1460 | 0.4646 | 57 | 75 | 104 | 135 | 169 | 201 | 239 | 281 | 355 | 0.0049 | 19.35 | 5.900 | 0.3617 | 50569.7 | 17000000 | 6670000000 | 2960000000000 | 0.5121 | 0.1476 | 0.0119 | 0.0010 | 0.0889 | 0.0089 | 0.1976 | 0.0207 | 0.1621 | 0.0720 | 0.1581 | 0.1519 | 0.1561 | 0.2002 | 0.0870 | 0.1322 | 0.0870 | 0.1686 | 0.0514 | 0.2446 | 0.0000 | 0.0006 | 0.0008 | 0.0006 | 0.0093 | 0.0025 | 0.0202 | 0.0153 | 0.0644 | 0.0567 | 0.1149 | 0.0943 | 0.0901 | 0.0732 | 0.1335 | 0.1115 | 0.5668 | 0.6452 | 0.0013 | 0.0090 | 0.0064 | 0.0162 | 0.0153 | 0.0252 | 0.0435 | 0.0629 | 0.1228 | 0.1457 | 0.1662 | 0.1853 | 0.1368 | 0.1097 | 0.1675 | 0.1583 | 0.3402 | 0.2878 | 0.0000 | 0.0019 | 0.0135 | 0.0348 | 0.0890 | 0.1277 | 0.1180 | 0.1750 | 0.4400 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1249 | 769 | | 4803 | 11247 | 502.2 | 83.00 | 67.05 | 122.38 | 382 | 431 | 463 | 488 | 508 | 528 | 552 | 579 | 608 | 0.0648 | 729 | 1.156 | 88.46 | 33.06 | 1 | 0.0477 | 229 | 0.0014 | 23.98 | 6.830 | 0.2358 | 259094.0 | 137000000 | 73800000000 | 40500000000000 | 0.4284 | 0.2133 | 0.0011 | 0.0000 | 0.0019 | 0.0000 | 0.0044 | 0.0000 | 0.0091 | 0.0002 | 0.0299 | 0.0136 | 0.0517 | 0.0206 | 0.0575 | 0.0124 | 0.0811 | 0.0183 | 0.7632 | 0.9350 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0002 | 0.0170 | 0.0136 | 0.0276 | 0.0206 | 0.0218 | 0.0124 | 0.0377 | 0.0183 | 0.8937 | 0.9350 | 0.0072 | 0.0000 | 0.0181 | 0.0000 | 0.0325 | 0.0000 | 0.0597 | 0.0000 | 0.0868 | 0.0000 | 0.1374 | 0.0000 | 0.1230 | 0.0000 | 0.1754 | 0.0000 | 0.3599 | 0.0000 | 0.0019 | 0.0016 | 0.0054 | 0.0140 | 0.0384 | 0.0594 | 0.0602 | 0.0889 | 0.7301 | 6 | 8 | 10 | 12 | 15 | 20 | 38 | 86 | 207 | 0.1665 | 6.51 | 3.350 | 0.6502 | 19470.7 | 8860000 | 4860000000 | 2970000000000 | 0.5816 | 0.0962 | 0.0324 | 0.0043 | 0.1477 | 0.0208 | 0.2216 | 0.0720 | 0.2090 | 0.1276 | 0.1658 | 0.1753 | 0.1189 | 0.1840 | 0.0613 | 0.1372 | 0.0216 | 0.1345 | 0.0216 | 0.1441 | 0.0007 | 0.0003 | 0.0010 | 0.0009 | 0.0034 | 0.0039 | 0.0172 | 0.0128 | 0.0540 | 0.0538 | 0.0890 | 0.0805 | 0.0639 | 0.0589 | 0.0907 | 0.0838 | 0.6801 | 0.7050 | 0.0000 | 0.0005 | 0.0013 | 0.0019 | 0.0030 | 0.0033 | 0.0166 | 0.0196 | 0.0675 | 0.0650 | 0.0968 | 0.1182 | 0.0739 | 0.0715 | 0.0994 | 0.1005 | 0.6416 | 0.6196 | 0.0004 | 0.0015 | 0.0034 | 0.0145 | 0.0574 | 0.1015 | 0.0624 | 0.0915 | 0.6673 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1030 | 654 | | 4733 | 10425 | 467.9 | 107.24 | 95.77 | 122.81 | 345 | 379 | 404 | 428 | 451 | 479 | 509 | 550 | 613 | 0.0706 | 736 | 0.617 | 150.66 | 41.15 | 1 | 0.0909 | 430 | 0.0008 | 55.01 | 7.358 | 0.1623 | 230448.0 | 120000000 | 65300000000 | 37500000000000 | 0.3787 | 0.2634 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0007 | 0.0134 | 0.0009 | 0.0647 | 0.0210 | 0.1390 | 0.0495 | 0.1451 | 0.0401 | 0.1678 | 0.0472 | 0.4677 | 0.8406 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0006 | 0.0057 | 0.0004 | 0.0302 | 0.0145 | 0.0629 | 0.0288 | 0.0577 | 0.0177 | 0.0847 | 0.0228 | 0.7570 | 0.9150 | 0.0023 | 0.0000 | 0.0070 | 0.0000 | 0.0151 | 0.0201 | 0.0568 | 0.0936 | 0.1230 | 0.1472 | 0.1647 | 0.2107 | 0.0974 | 0.1037 | 0.1334 | 0.1171 | 0.4002 | 0.3077 | 0.0005 | 0.0024 | 0.0063 | 0.0250 | 0.0794 | 0.1414 | 0.1034 | 0.1255 | 0.5161 | 8 | 10 | 12 | 16 | 31 | 66 | 119 | 187 | 269 | 0.0567 | 15.85 | 4.921 | 0.5294 | 24254.7 | 8620000 | 3790000000 | 1970000000000 | 0.5285 | 0.1189 | 0.0542 | 0.0020 | 0.2045 | 0.0127 | 0.3074 | 0.1029 | 0.1864 | 0.1470 | 0.1140 | 0.2238 | 0.0695 | 0.2285 | 0.0320 | 0.1142 | 0.0209 | 0.0788 | 0.0111 | 0.0902 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0003 | 0.0011 | 0.0095 | 0.0066 | 0.0504 | 0.0403 | 0.0831 | 0.0816 | 0.0652 | 0.0504 | 0.0967 | 0.0809 | 0.6944 | 0.7391 | 0.0000 | 0.0000 | 0.0013 | 0.0003 | 0.0019 | 0.0021 | 0.0107 | 0.0164 | 0.0630 | 0.0649 | 0.1047 | 0.1238 | 0.0740 | 0.0795 | 0.1160 | 0.1196 | 0.6286 | 0.5934 | 0.0000 | 0.0003 | 0.0014 | 0.0107 | 0.0546 | 0.0976 | 0.0658 | 0.1029 | 0.6668 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 797 | 276 | | 3081 | 14857 | 257.1 | 73.60 | 95.99 | 124.19 | 175 | 187 | 202 | 218 | 241 | 266 | 296 | 325 | 367 | 0.0703 | 1045 | 0.709 | 60.54 | 16.03 | 2 | 0.0568 | 175 | 0.0097 | 3.01 | 5.047 | 0.5308 | 71538.3 | 21500000 | 6880000000 | 2330000000000 | 0.3683 | 0.2682 | 0.0023 | 0.0000 | 0.0053 | 0.0000 | 0.0107 | 0.0015 | 0.0328 | 0.0041 | 0.0710 | 0.0354 | 0.1154 | 0.0479 | 0.1054 | 0.0420 | 0.1398 | 0.0593 | 0.5172 | 0.8099 | 0.0014 | 0.0000 | 0.0019 | 0.0000 | 0.0043 | 0.0007 | 0.0125 | 0.0013 | 0.0288 | 0.0202 | 0.0389 | 0.0276 | 0.0408 | 0.0189 | 0.0504 | 0.0315 | 0.8209 | 0.8998 | 0.0013 | 0.0000 | 0.0000 | 0.0111 | 0.0090 | 0.0028 | 0.0168 | 0.0306 | 0.0530 | 0.0889 | 0.0917 | 0.1306 | 0.0646 | 0.1139 | 0.0904 | 0.1500 | 0.6731 | 0.4722 | 0.0015 | 0.0015 | 0.0052 | 0.0126 | 0.0238 | 0.0535 | 0.0416 | 0.0558 | 0.8045 | 12 | 19 | 29 | 42 | 54 | 70 | 95 | 135 | 230 | 0.0663 | 4.54 | 3.869 | 0.7237 | 24635.6 | 11400000 | 7270000000 | 5520000000000 | 0.4425 | 0.1810 | 0.0092 | 0.0039 | 0.0252 | 0.0102 | 0.0406 | 0.0158 | 0.0729 | 0.0304 | 0.1237 | 0.0621 | 0.1566 | 0.0900 | 0.1494 | 0.0954 | 0.1869 | 0.1280 | 0.2356 | 0.5641 | 0.0025 | 0.0017 | 0.0033 | 0.0049 | 0.0040 | 0.0052 | 0.0113 | 0.0100 | 0.0302 | 0.0240 | 0.0458 | 0.0344 | 0.0473 | 0.0408 | 0.0691 | 0.0611 | 0.7864 | 0.8179 | 0.0008 | 0.0007 | 0.0034 | 0.0027 | 0.0059 | 0.0050 | 0.0163 | 0.0174 | 0.0487 | 0.0557 | 0.0704 | 0.0795 | 0.0637 | 0.0651 | 0.0789 | 0.0849 | 0.7118 | 0.6890 | 0.0011 | 0.0052 | 0.0059 | 0.0142 | 0.0363 | 0.0542 | 0.0582 | 0.0716 | 0.7533 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 461 | 123 | | 3257 | 6809 | 514.7 | 105.53 | 61.25 | 124.20 | 368 | 433 | 474 | 500 | 525 | 551 | 579 | 608 | 638 | 0.0824 | 561 | 0.766 | 87.00 | 16.03 | 3 | 0.0620 | 202 | 0.0010 | 52.75 | 7.148 | 0.1825 | 276060.0 | 153000000 | 86800000000 | 50400000000000 | 0.4286 | 0.2196 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0068 | 0.0000 | 0.0140 | 0.0013 | 0.0512 | 0.0198 | 0.0978 | 0.0406 | 0.0965 | 0.0227 | 0.1277 | 0.0373 | 0.6046 | 0.8782 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0029 | 0.0013 | 0.0220 | 0.0197 | 0.0447 | 0.0384 | 0.0293 | 0.0184 | 0.0411 | 0.0288 | 0.8596 | 0.8934 | 0.0077 | 0.1333 | 0.0173 | 0.1333 | 0.0288 | 0.0667 | 0.0865 | 0.1333 | 0.1404 | 0.2667 | 0.1442 | 0.1333 | 0.1231 | 0.0000 | 0.1654 | 0.1333 | 0.2865 | 0.0000 | 0.0011 | 0.0023 | 0.0079 | 0.0186 | 0.0514 | 0.0814 | 0.0729 | 0.1040 | 0.6605 | 7 | 9 | 11 | 12 | 14 | 19 | 31 | 56 | 175 | 0.1883 | 7.43 | 3.201 | 0.7374 | 19174.6 | 10600000 | 7360000000 | 5780000000000 | 0.4921 | 0.1647 | 0.0338 | 0.0142 | 0.0549 | 0.0252 | 0.0717 | 0.0377 | 0.0928 | 0.0660 | 0.1392 | 0.0849 | 0.1814 | 0.1289 | 0.2363 | 0.1321 | 0.1097 | 0.1525 | 0.0802 | 0.3585 | 0.0034 | 0.0045 | 0.0048 | 0.0078 | 0.0034 | 0.0111 | 0.0109 | 0.0167 | 0.0212 | 0.0279 | 0.0519 | 0.0507 | 0.0355 | 0.0423 | 0.0444 | 0.0591 | 0.8245 | 0.7799 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0073 | 0.0078 | 0.0334 | 0.0336 | 0.0465 | 0.0509 | 0.0302 | 0.0259 | 0.0522 | 0.0578 | 0.8280 | 0.8240 | 0.0008 | 0.0008 | 0.0046 | 0.0106 | 0.0236 | 0.0540 | 0.0274 | 0.0547 | 0.8237 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 145 | 220 | | 5756 | 11661 | 118.5 | 36.39 | 167.20 | 124.25 | 81 | 90 | 98 | 104 | 111 | 118 | 128 | 143 | 165 | 0.0846 | 986 | 0.856 | 102.96 | 27.00 | 1 | 0.0480 | 276 | 0.0023 | 23.04 | 6.430 | 0.2521 | 15367.1 | 2200000 | 352000000 | 62600000000 | 0.4200 | 0.2279 | 0.0020 | 0.0000 | 0.0029 | 0.0002 | 0.0150 | 0.0010 | 0.0444 | 0.0056 | 0.1120 | 0.0292 | 0.1639 | 0.0606 | 0.1681 | 0.0606 | 0.2099 | 0.0964 | 0.2818 | 0.7463 | 0.0014 | 0.0000 | 0.0009 | 0.0000 | 0.0050 | 0.0007 | 0.0159 | 0.0020 | 0.0515 | 0.0182 | 0.0735 | 0.0309 | 0.0871 | 0.0309 | 0.1288 | 0.0545 | 0.6358 | 0.8628 | 0.0043 | 0.0018 | 0.0130 | 0.0107 | 0.0260 | 0.0178 | 0.0582 | 0.0516 | 0.1094 | 0.1335 | 0.1432 | 0.2046 | 0.1102 | 0.1174 | 0.1363 | 0.1459 | 0.3993 | 0.3167 | 0.0030 | 0.0057 | 0.0174 | 0.0449 | 0.0858 | 0.1233 | 0.1054 | 0.1337 | 0.4808 | 25 | 50 | 81 | 110 | 144 | 177 | 218 | 274 | 343 | 0.0021 | 46.18 | 7.043 | 0.2601 | 43391.7 | 14100000 | 5330000000 | 2240000000000 | 0.5309 | 0.1392 | 0.0066 | 0.0007 | 0.0509 | 0.0066 | 0.1329 | 0.0201 | 0.1554 | 0.0531 | 0.1718 | 0.1357 | 0.1718 | 0.1713 | 0.1337 | 0.1501 | 0.1001 | 0.1692 | 0.0766 | 0.2933 | 0.0002 | 0.0003 | 0.0019 | 0.0009 | 0.0047 | 0.0031 | 0.0146 | 0.0122 | 0.0480 | 0.0427 | 0.0812 | 0.0603 | 0.0796 | 0.0606 | 0.1017 | 0.0883 | 0.6681 | 0.7316 | 0.0018 | 0.0022 | 0.0028 | 0.0073 | 0.0117 | 0.0105 | 0.0273 | 0.0350 | 0.0734 | 0.0815 | 0.1175 | 0.1238 | 0.0948 | 0.0986 | 0.1233 | 0.1371 | 0.5474 | 0.5040 | 0.0018 | 0.0034 | 0.0086 | 0.0243 | 0.0633 | 0.0955 | 0.0865 | 0.1196 | 0.5971 | ||
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 201 | 479 | | 6474 | 26300 | 321.0 | 57.21 | 100.08 | 124.51 | 249 | 270 | 287 | 303 | 318 | 334 | 351 | 372 | 398 | 0.0455 | 1196 | 1.134 | 99.86 | 37.59 | 2 | 0.0394 | 255 | 0.0006 | 73.06 | 7.553 | 0.1323 | 106297.0 | 36300000 | 12700000000 | 4580000000000 | 0.4555 | 0.1968 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0030 | 0.0002 | 0.0144 | 0.0008 | 0.0453 | 0.0123 | 0.1133 | 0.0261 | 0.1258 | 0.0247 | 0.1709 | 0.0467 | 0.5257 | 0.8892 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0002 | 0.0069 | 0.0003 | 0.0227 | 0.0113 | 0.0501 | 0.0206 | 0.0538 | 0.0157 | 0.0774 | 0.0244 | 0.7881 | 0.9275 | 0.0044 | 0.0805 | 0.0187 | 0.0575 | 0.0430 | 0.1839 | 0.0926 | 0.0920 | 0.1599 | 0.3103 | 0.1985 | 0.1379 | 0.1279 | 0.0460 | 0.1709 | 0.0805 | 0.1841 | 0.0115 | 0.0010 | 0.0025 | 0.0127 | 0.0290 | 0.0762 | 0.1275 | 0.1093 | 0.1393 | 0.5025 | 11 | 13 | 15 | 20 | 36 | 70 | 125 | 189 | 272 | 0.0574 | 15.56 | 4.832 | 0.5328 | 25517.2 | 9400000 | 4360000000 | 2400000000000 | 0.4719 | 0.1702 | 0.0761 | 0.0028 | 0.2702 | 0.0198 | 0.3311 | 0.1800 | 0.1322 | 0.2075 | 0.0992 | 0.2192 | 0.0530 | 0.1607 | 0.0236 | 0.0959 | 0.0105 | 0.0697 | 0.0042 | 0.0445 | 0.0001 | 0.0000 | 0.0007 | 0.0004 | 0.0009 | 0.0012 | 0.0101 | 0.0086 | 0.0551 | 0.0465 | 0.1067 | 0.0874 | 0.0756 | 0.0609 | 0.1039 | 0.0939 | 0.6470 | 0.7011 | 0.0004 | 0.0005 | 0.0005 | 0.0019 | 0.0037 | 0.0034 | 0.0152 | 0.0180 | 0.0736 | 0.0826 | 0.1416 | 0.1590 | 0.0968 | 0.1084 | 0.1346 | 0.1429 | 0.5337 | 0.4833 | 0.0006 | 0.0003 | 0.0023 | 0.0133 | 0.0603 | 0.1279 | 0.0841 | 0.1215 | 0.5898 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 552 | 584 | | 9730 | 22960 | 539.9 | 116.17 | 146.55 | 125.01 | 407 | 442 | 468 | 494 | 522 | 550 | 584 | 629 | 705 | 0.0487 | 1118 | 1.101 | 111.89 | 44.42 | 1 | 0.0312 | 304 | 0.0009 | 44.66 | 7.368 | 0.1782 | 304940.0 | 180000000 | 112000000000 | 72500000000000 | 0.4444 | 0.1987 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0022 | 0.0000 | 0.0102 | 0.0014 | 0.0583 | 0.0160 | 0.1054 | 0.0336 | 0.1103 | 0.0294 | 0.1389 | 0.0462 | 0.5744 | 0.8733 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0010 | 0.0000 | 0.0048 | 0.0000 | 0.0270 | 0.0090 | 0.0515 | 0.0177 | 0.0520 | 0.0107 | 0.0667 | 0.0200 | 0.7970 | 0.9425 | 0.0006 | 0.0034 | 0.0104 | 0.0068 | 0.0097 | 0.0273 | 0.0420 | 0.0528 | 0.0981 | 0.1772 | 0.1510 | 0.1772 | 0.1139 | 0.1244 | 0.1364 | 0.1516 | 0.4379 | 0.2794 | 0.0009 | 0.0038 | 0.0081 | 0.0268 | 0.0648 | 0.0997 | 0.0955 | 0.1138 | 0.5866 | 26 | 46 | 69 | 93 | 116 | 141 | 173 | 217 | 307 | 0.0087 | 14.33 | 5.634 | 0.4373 | 37104.1 | 13800000 | 6720000000 | 4000000000000 | 0.5360 | 0.1367 | 0.0163 | 0.0005 | 0.0637 | 0.0048 | 0.1580 | 0.0328 | 0.1548 | 0.0671 | 0.1728 | 0.1313 | 0.1646 | 0.1718 | 0.1121 | 0.1434 | 0.0945 | 0.1555 | 0.0632 | 0.2927 | 0.0004 | 0.0002 | 0.0009 | 0.0007 | 0.0048 | 0.0016 | 0.0166 | 0.0115 | 0.0663 | 0.0489 | 0.1136 | 0.0904 | 0.0895 | 0.0739 | 0.1218 | 0.1031 | 0.5861 | 0.6696 | 0.0010 | 0.0037 | 0.0046 | 0.0085 | 0.0097 | 0.0132 | 0.0331 | 0.0351 | 0.1031 | 0.1074 | 0.1483 | 0.1604 | 0.1084 | 0.1050 | 0.1378 | 0.1369 | 0.4538 | 0.4299 | 0.0014 | 0.0023 | 0.0070 | 0.0228 | 0.0831 | 0.1367 | 0.1048 | 0.1260 | 0.5159 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 688 | 724 | | 382 | 3170 | 111.2 | 49.61 | 43.27 | 125.08 | 45 | 55 | 71 | 91 | 111 | 133 | 151 | 163 | 177 | 0.1344 | 426 | 0.422 | 253.34 | 46.17 | 1 | 2.3037 | 880 | 0.0037 | 31.49 | 5.680 | 0.1888 | 14813.4 | 2190000 | 345000000 | 56300000000 | 0.2747 | 0.3491 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.2262 | 0.0345 | 0.3929 | 0.1379 | 0.2857 | 0.2184 | 0.0357 | 0.1494 | 0.0595 | 0.2184 | 0.0000 | 0.2356 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0072 | 0.0681 | 0.0578 | 0.0851 | 0.0866 | 0.0511 | 0.0433 | 0.0681 | 0.0650 | 0.7191 | 0.7401 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0194 | 0.0927 | 0.1553 | 0.1192 | 0.1165 | 0.0397 | 0.0971 | 0.1060 | 0.1165 | 0.6424 | 0.4854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0733 | 0.1257 | 0.0314 | 0.0733 | 0.6963 | 7 | 8 | 9 | 10 | 10 | 11 | 12 | 15 | 33 | 0.6117 | 5.34 | 1.436 | 0.8850 | 17511.8 | 11000000 | 7740000000 | 5940000000000 | 0.6927 | 0.0495 | 0.0357 | 0.0000 | 0.1429 | 0.0385 | 0.2857 | 0.0641 | 0.2143 | 0.1538 | 0.1786 | 0.2436 | 0.1429 | 0.1923 | 0.0000 | 0.1154 | 0.0000 | 0.1538 | 0.0000 | 0.0385 | 0.0032 | 0.0000 | 0.0064 | 0.0085 | 0.0064 | 0.0141 | 0.0129 | 0.0226 | 0.0386 | 0.0621 | 0.0611 | 0.0424 | 0.0675 | 0.0621 | 0.0868 | 0.1017 | 0.7170 | 0.6864 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0035 | 0.0000 | 0.0106 | 0.0181 | 0.0565 | 0.0471 | 0.0636 | 0.0870 | 0.0777 | 0.0725 | 0.0777 | 0.0725 | 0.7102 | 0.6993 | 0.0000 | 0.0000 | 0.0068 | 0.0102 | 0.0476 | 0.0612 | 0.0714 | 0.0884 | 0.7143 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 193 | 840 | | 364 | 9991 | 79.4 | 12.33 | 120.69 | 125.11 | 64 | 69 | 71 | 74 | 78 | 82 | 86 | 91 | 97 | 0.0656 | 655 | 0.892 | 100.23 | 30.02 | 0 | 0.7033 | 256 | 0.0097 | 8.20 | 4.818 | 0.3329 | 6458.0 | 537560 | 45800000 | 3980000000 | 0.4026 | 0.2222 | 0.0000 | 0.0000 | 0.0248 | 0.0028 | 0.0106 | 0.0055 | 0.0496 | 0.0138 | 0.1028 | 0.0608 | 0.1950 | 0.1326 | 0.1915 | 0.0856 | 0.2340 | 0.1105 | 0.1915 | 0.5884 | 0.0000 | 0.0000 | 0.0210 | 0.0027 | 0.0060 | 0.0055 | 0.0330 | 0.0137 | 0.0571 | 0.0604 | 0.1171 | 0.1319 | 0.0781 | 0.0742 | 0.1171 | 0.0934 | 0.5706 | 0.6181 | 0.0196 | 0.0000 | 0.0980 | 1.0000 | 0.0392 | 0.0000 | 0.2549 | 0.0000 | 0.1765 | 0.0000 | 0.2157 | 0.0000 | 0.0980 | 0.0000 | 0.0980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0229 | 0.0571 | 0.0400 | 0.0971 | 0.1371 | 0.1371 | 0.1771 | 0.3314 | 24 | 37 | 47 | 57 | 70 | 90 | 126 | 190 | 293 | 0.0082 | 25.67 | 5.863 | 0.4219 | 30214.6 | 11500000 | 5470000000 | 2990000000000 | 0.6670 | 0.0790 | 0.0168 | 0.0063 | 0.0841 | 0.0145 | 0.1639 | 0.0396 | 0.1869 | 0.0903 | 0.1913 | 0.1538 | 0.1665 | 0.1778 | 0.0939 | 0.1436 | 0.0709 | 0.1429 | 0.0257 | 0.2312 | 0.0013 | 0.0029 | 0.0042 | 0.0050 | 0.0088 | 0.0091 | 0.0255 | 0.0213 | 0.0682 | 0.0615 | 0.1043 | 0.0886 | 0.0823 | 0.0797 | 0.1139 | 0.1042 | 0.5915 | 0.6276 | 0.0008 | 0.0009 | 0.0049 | 0.0070 | 0.0167 | 0.0127 | 0.0318 | 0.0417 | 0.0864 | 0.0961 | 0.1262 | 0.1298 | 0.0936 | 0.1039 | 0.1259 | 0.1373 | 0.5136 | 0.4706 | 0.0016 | 0.0055 | 0.0109 | 0.0257 | 0.0792 | 0.1136 | 0.0911 | 0.1171 | 0.5553 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1049 | 270 | | 3875 | 7952 | 133.1 | 35.91 | 157.83 | 125.74 | 94 | 104 | 113 | 121 | 128 | 136 | 145 | 157 | 179 | 0.0832 | 662 | 0.854 | 78.82 | 25.55 | 2 | 0.0565 | 219 | 0.0020 | 26.25 | 6.494 | 0.2455 | 18997.6 | 2930000 | 490000000 | 89600000000 | 0.4209 | 0.2213 | 0.0000 | 0.0003 | 0.0004 | 0.0000 | 0.0074 | 0.0003 | 0.0302 | 0.0020 | 0.0944 | 0.0294 | 0.1627 | 0.0582 | 0.1605 | 0.0616 | 0.1828 | 0.0913 | 0.3616 | 0.7570 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0003 | 0.0462 | 0.0196 | 0.0716 | 0.0346 | 0.0726 | 0.0291 | 0.1044 | 0.0471 | 0.6921 | 0.8694 | 0.0086 | 0.0097 | 0.0143 | 0.0065 | 0.0399 | 0.0259 | 0.0799 | 0.1003 | 0.1241 | 0.1586 | 0.1526 | 0.1715 | 0.0984 | 0.1100 | 0.1184 | 0.1683 | 0.3638 | 0.2492 | 0.0024 | 0.0083 | 0.0166 | 0.0391 | 0.1073 | 0.1375 | 0.1203 | 0.1316 | 0.4369 | 26 | 44 | 68 | 98 | 128 | 163 | 203 | 251 | 336 | 0.0035 | 41.32 | 6.588 | 0.3220 | 40720.6 | 13800000 | 5550000000 | 2540000000000 | 0.4558 | 0.2138 | 0.0196 | 0.0022 | 0.0713 | 0.0072 | 0.1578 | 0.0421 | 0.1767 | 0.0623 | 0.2000 | 0.1326 | 0.1804 | 0.1870 | 0.1084 | 0.1581 | 0.0531 | 0.1675 | 0.0327 | 0.2410 | 0.0012 | 0.0000 | 0.0015 | 0.0021 | 0.0055 | 0.0037 | 0.0159 | 0.0118 | 0.0585 | 0.0468 | 0.0938 | 0.0773 | 0.0774 | 0.0664 | 0.1074 | 0.0880 | 0.6388 | 0.7040 | 0.0008 | 0.0034 | 0.0053 | 0.0087 | 0.0120 | 0.0135 | 0.0361 | 0.0429 | 0.0847 | 0.1118 | 0.1295 | 0.1301 | 0.1043 | 0.1186 | 0.1401 | 0.1533 | 0.4872 | 0.4178 | 0.0006 | 0.0033 | 0.0108 | 0.0222 | 0.0752 | 0.1049 | 0.0869 | 0.1254 | 0.5707 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 414 | 325 | | 5437 | 7882 | 437.9 | 83.20 | 101.98 | 125.88 | 341 | 366 | 387 | 407 | 426 | 445 | 470 | 508 | 561 | 0.1009 | 795 | 1.215 | 56.61 | 22.20 | 1 | 0.0270 | 147 | 0.0013 | 34.95 | 6.913 | 0.2030 | 198637.0 | 93400000 | 45500000000 | 22900000000000 | 0.4444 | 0.2029 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0000 | 0.0120 | 0.0013 | 0.0499 | 0.0139 | 0.1259 | 0.0375 | 0.1288 | 0.0278 | 0.1661 | 0.0447 | 0.5165 | 0.8745 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0047 | 0.0004 | 0.0231 | 0.0107 | 0.0658 | 0.0258 | 0.0594 | 0.0103 | 0.0912 | 0.0214 | 0.7556 | 0.9315 | 0.0000 | 0.0057 | 0.0056 | 0.0230 | 0.0169 | 0.1092 | 0.0666 | 0.1782 | 0.1332 | 0.1494 | 0.1603 | 0.1839 | 0.0971 | 0.1149 | 0.1332 | 0.0977 | 0.3871 | 0.1379 | 0.0013 | 0.0051 | 0.0161 | 0.0442 | 0.0794 | 0.1219 | 0.0968 | 0.1125 | 0.5227 | 6 | 8 | 10 | 15 | 37 | 76 | 132 | 208 | 298 | 0.0817 | 10.67 | 4.715 | 0.5608 | 26243.7 | 8800000 | 3420000000 | 1480000000000 | 0.4564 | 0.1723 | 0.0249 | 0.0017 | 0.0817 | 0.0059 | 0.2664 | 0.0462 | 0.2433 | 0.0891 | 0.1456 | 0.1756 | 0.1155 | 0.2311 | 0.0639 | 0.1395 | 0.0373 | 0.1218 | 0.0213 | 0.1891 | 0.0007 | 0.0003 | 0.0007 | 0.0006 | 0.0029 | 0.0015 | 0.0098 | 0.0052 | 0.0334 | 0.0268 | 0.0579 | 0.0534 | 0.0435 | 0.0365 | 0.0648 | 0.0589 | 0.7863 | 0.8169 | 0.0008 | 0.0000 | 0.0000 | 0.0004 | 0.0016 | 0.0009 | 0.0148 | 0.0152 | 0.0409 | 0.0567 | 0.0678 | 0.0844 | 0.0650 | 0.0612 | 0.0770 | 0.0933 | 0.7319 | 0.6878 | 0.0004 | 0.0015 | 0.0025 | 0.0105 | 0.0384 | 0.0613 | 0.0537 | 0.0758 | 0.7560 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 426 | 374 | | 4318 | 14420 | 143.7 | 34.49 | 119.50 | 125.97 | 103 | 114 | 123 | 131 | 140 | 148 | 158 | 170 | 188 | 0.0620 | 894 | 1.020 | 115.11 | 27.29 | 1 | 0.0602 | 260 | 0.0019 | 27.37 | 6.560 | 0.2321 | 21832.7 | 3510000 | 599000000 | 108000000000 | 0.4264 | 0.2220 | 0.0004 | 0.0000 | 0.0035 | 0.0005 | 0.0196 | 0.0012 | 0.0369 | 0.0027 | 0.0914 | 0.0222 | 0.1656 | 0.0530 | 0.1672 | 0.0527 | 0.1770 | 0.0782 | 0.3383 | 0.7894 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0000 | 0.0113 | 0.0014 | 0.0416 | 0.0148 | 0.0794 | 0.0319 | 0.0708 | 0.0195 | 0.1002 | 0.0380 | 0.6908 | 0.8945 | 0.0049 | 0.0114 | 0.0160 | 0.0114 | 0.0294 | 0.0456 | 0.0896 | 0.1787 | 0.1521 | 0.2129 | 0.1816 | 0.2053 | 0.1411 | 0.0913 | 0.1546 | 0.1293 | 0.2307 | 0.1141 | 0.0005 | 0.0031 | 0.0112 | 0.0386 | 0.0910 | 0.1352 | 0.1256 | 0.1546 | 0.4403 | 17 | 24 | 35 | 47 | 65 | 91 | 142 | 211 | 313 | 0.0080 | 38.15 | 6.234 | 0.3884 | 30147.3 | 10600000 | 4400000000 | 2040000000000 | 0.5107 | 0.1394 | 0.0427 | 0.0034 | 0.1280 | 0.0141 | 0.2110 | 0.0584 | 0.1420 | 0.1202 | 0.1528 | 0.1742 | 0.1412 | 0.1803 | 0.1009 | 0.1302 | 0.0559 | 0.1289 | 0.0256 | 0.1903 | 0.0007 | 0.0013 | 0.0025 | 0.0025 | 0.0054 | 0.0058 | 0.0116 | 0.0120 | 0.0497 | 0.0465 | 0.0797 | 0.0690 | 0.0606 | 0.0582 | 0.0869 | 0.0833 | 0.7029 | 0.7214 | 0.0002 | 0.0008 | 0.0009 | 0.0008 | 0.0044 | 0.0074 | 0.0114 | 0.0183 | 0.0634 | 0.0731 | 0.0992 | 0.1123 | 0.0727 | 0.0847 | 0.1113 | 0.1107 | 0.6365 | 0.5920 | 0.0004 | 0.0021 | 0.0035 | 0.0136 | 0.0496 | 0.0910 | 0.0683 | 0.0899 | 0.6816 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1099 | 456 | | 4384 | 11255 | 330.4 | 82.17 | 122.23 | 126.09 | 224 | 258 | 283 | 305 | 326 | 347 | 372 | 400 | 446 | 0.0782 | 880 | 1.074 | 91.24 | 29.15 | 1 | 0.0527 | 231 | 0.0005 | 119.89 | 7.749 | 0.1150 | 115898.0 | 42900000 | 16600000000 | 6700000000000 | 0.4213 | 0.2264 | 0.0004 | 0.0003 | 0.0004 | 0.0000 | 0.0020 | 0.0008 | 0.0145 | 0.0036 | 0.0912 | 0.0281 | 0.1739 | 0.0521 | 0.1546 | 0.0521 | 0.1784 | 0.0727 | 0.3846 | 0.7904 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0002 | 0.0038 | 0.0012 | 0.0353 | 0.0176 | 0.0695 | 0.0312 | 0.0601 | 0.0279 | 0.0917 | 0.0391 | 0.7384 | 0.8827 | 0.0032 | 0.0063 | 0.0032 | 0.0158 | 0.0222 | 0.0095 | 0.0549 | 0.0886 | 0.1267 | 0.1203 | 0.1426 | 0.2089 | 0.0971 | 0.1582 | 0.1204 | 0.1487 | 0.4298 | 0.2437 | 0.0019 | 0.0024 | 0.0081 | 0.0276 | 0.0676 | 0.1257 | 0.0995 | 0.1185 | 0.5488 | 12 | 17 | 26 | 41 | 66 | 110 | 167 | 231 | 315 | 0.0244 | 16.78 | 5.456 | 0.4535 | 30835.4 | 10200000 | 3890000000 | 1660000000000 | 0.5357 | 0.1392 | 0.0679 | 0.0019 | 0.2575 | 0.0224 | 0.3413 | 0.1296 | 0.1487 | 0.2072 | 0.0978 | 0.2115 | 0.0459 | 0.1648 | 0.0279 | 0.1034 | 0.0120 | 0.0858 | 0.0010 | 0.0734 | 0.0000 | 0.0000 | 0.0013 | 0.0002 | 0.0025 | 0.0033 | 0.0197 | 0.0144 | 0.0659 | 0.0599 | 0.1055 | 0.0938 | 0.0848 | 0.0719 | 0.1153 | 0.1097 | 0.6050 | 0.6468 | 0.0013 | 0.0012 | 0.0024 | 0.0024 | 0.0109 | 0.0115 | 0.0270 | 0.0329 | 0.0840 | 0.0922 | 0.1224 | 0.1351 | 0.1038 | 0.1031 | 0.1234 | 0.1278 | 0.5248 | 0.4938 | 0.0000 | 0.0014 | 0.0058 | 0.0175 | 0.0782 | 0.1175 | 0.0896 | 0.1249 | 0.5651 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 764 | 363 | | 6534 | 17604 | 111.7 | 25.73 | 145.88 | 126.49 | 83 | 92 | 97 | 103 | 108 | 114 | 120 | 129 | 143 | 0.0564 | 993 | 1.124 | 94.02 | 35.78 | 1 | 0.0376 | 246 | 0.0034 | 14.04 | 6.028 | 0.2979 | 13134.9 | 1640000 | 217000000 | 30900000000 | 0.4275 | 0.2230 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0075 | 0.0010 | 0.0183 | 0.0028 | 0.0649 | 0.0170 | 0.1122 | 0.0403 | 0.1486 | 0.0380 | 0.1796 | 0.0591 | 0.4674 | 0.8418 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0028 | 0.0000 | 0.0079 | 0.0003 | 0.0333 | 0.0128 | 0.0545 | 0.0232 | 0.0712 | 0.0172 | 0.0935 | 0.0318 | 0.7365 | 0.9147 | 0.0071 | 0.0174 | 0.0202 | 0.0174 | 0.0333 | 0.0378 | 0.0787 | 0.0930 | 0.1403 | 0.1715 | 0.1675 | 0.2151 | 0.1120 | 0.0959 | 0.1534 | 0.1163 | 0.2876 | 0.2355 | 0.0028 | 0.0083 | 0.0160 | 0.0333 | 0.0850 | 0.1273 | 0.1197 | 0.1377 | 0.4700 | 21 | 39 | 60 | 85 | 114 | 147 | 184 | 233 | 308 | 0.0032 | 38.65 | 6.813 | 0.3067 | 37278.1 | 13400000 | 6170000000 | 3410000000000 | 0.5292 | 0.1463 | 0.0158 | 0.0007 | 0.0848 | 0.0055 | 0.1961 | 0.0342 | 0.1492 | 0.0782 | 0.1694 | 0.1525 | 0.1634 | 0.1913 | 0.1004 | 0.1376 | 0.0710 | 0.1535 | 0.0499 | 0.2464 | 0.0006 | 0.0002 | 0.0008 | 0.0006 | 0.0028 | 0.0019 | 0.0142 | 0.0107 | 0.0533 | 0.0454 | 0.0994 | 0.0759 | 0.0817 | 0.0681 | 0.1120 | 0.0951 | 0.6354 | 0.7021 | 0.0009 | 0.0016 | 0.0027 | 0.0029 | 0.0108 | 0.0144 | 0.0315 | 0.0406 | 0.0887 | 0.1021 | 0.1392 | 0.1515 | 0.1106 | 0.1145 | 0.1317 | 0.1242 | 0.4840 | 0.4482 | 0.0004 | 0.0023 | 0.0046 | 0.0198 | 0.0710 | 0.1242 | 0.0992 | 0.1273 | 0.5511 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 889 | 579 | | 5344 | 14258 | 479.3 | 73.36 | 59.66 | 126.81 | 384 | 417 | 439 | 460 | 479 | 496 | 514 | 540 | 582 | 0.0560 | 799 | 1.214 | 72.84 | 31.83 | 1 | 0.0378 | 202 | 0.0020 | 11.27 | 6.511 | 0.3208 | 235079.0 | 118000000 | 60300000000 | 31500000000000 | 0.4020 | 0.2453 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0066 | 0.0002 | 0.0216 | 0.0122 | 0.0337 | 0.0213 | 0.0309 | 0.0112 | 0.0475 | 0.0182 | 0.8575 | 0.9369 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0002 | 0.0127 | 0.0122 | 0.0206 | 0.0213 | 0.0145 | 0.0112 | 0.0247 | 0.0167 | 0.9252 | 0.9384 | 0.0000 | 1.0000 | 0.0232 | 0.0000 | 0.0066 | 0.0000 | 0.0381 | 0.0000 | 0.0381 | 0.0000 | 0.0614 | 0.0000 | 0.0779 | 0.0000 | 0.0962 | 0.0000 | 0.6584 | 0.0000 | 0.0019 | 0.0026 | 0.0071 | 0.0160 | 0.0360 | 0.0527 | 0.0605 | 0.0854 | 0.7379 | 6 | 7 | 8 | 9 | 11 | 14 | 23 | 58 | 184 | 0.1961 | 6.16 | 3.029 | 0.6633 | 19637.6 | 11000000 | 8130000000 | 7350000000000 | 0.5394 | 0.1197 | 0.0721 | 0.0088 | 0.1081 | 0.0431 | 0.2450 | 0.1186 | 0.1766 | 0.0958 | 0.1315 | 0.1511 | 0.1045 | 0.1722 | 0.0829 | 0.1178 | 0.0541 | 0.1283 | 0.0252 | 0.1643 | 0.0010 | 0.0000 | 0.0013 | 0.0011 | 0.0048 | 0.0056 | 0.0166 | 0.0189 | 0.0507 | 0.0498 | 0.0842 | 0.0715 | 0.0555 | 0.0540 | 0.0778 | 0.0791 | 0.7083 | 0.7200 | 0.0008 | 0.0004 | 0.0027 | 0.0029 | 0.0023 | 0.0037 | 0.0139 | 0.0166 | 0.0616 | 0.0605 | 0.0953 | 0.0957 | 0.0581 | 0.0609 | 0.0817 | 0.0787 | 0.6836 | 0.6807 | 0.0007 | 0.0021 | 0.0021 | 0.0220 | 0.0535 | 0.0839 | 0.0676 | 0.0740 | 0.6941 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 158 | 814 | | 6792 | 9233 | 438.4 | 87.62 | 129.25 | 126.89 | 328 | 360 | 387 | 410 | 432 | 453 | 478 | 510 | 563 | 0.1039 | 959 | 1.120 | 105.12 | 29.02 | 1 | 0.0346 | 235 | 0.0009 | 45.63 | 7.284 | 0.1766 | 199847.0 | 94600000 | 46500000000 | 23600000000000 | 0.4114 | 0.2340 | 0.0002 | 0.0000 | 0.0009 | 0.0002 | 0.0029 | 0.0003 | 0.0152 | 0.0014 | 0.0530 | 0.0166 | 0.1082 | 0.0302 | 0.1148 | 0.0269 | 0.1594 | 0.0440 | 0.5454 | 0.8804 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0064 | 0.0000 | 0.0246 | 0.0109 | 0.0515 | 0.0199 | 0.0494 | 0.0108 | 0.0729 | 0.0223 | 0.7933 | 0.9361 | 0.0091 | 0.0087 | 0.0172 | 0.0435 | 0.0199 | 0.0913 | 0.0661 | 0.1174 | 0.1024 | 0.2261 | 0.1386 | 0.1174 | 0.1232 | 0.1739 | 0.1132 | 0.0870 | 0.4103 | 0.1348 | 0.0006 | 0.0025 | 0.0094 | 0.0253 | 0.0738 | 0.1200 | 0.1088 | 0.1385 | 0.5211 | 15 | 21 | 36 | 60 | 91 | 123 | 163 | 221 | 310 | 0.0144 | 22.41 | 5.893 | 0.4120 | 32805.8 | 11500000 | 4920000000 | 2420000000000 | 0.5918 | 0.1102 | 0.0326 | 0.0008 | 0.0932 | 0.0126 | 0.1546 | 0.0502 | 0.1430 | 0.0942 | 0.1492 | 0.1468 | 0.1430 | 0.1554 | 0.1072 | 0.1181 | 0.1049 | 0.1370 | 0.0723 | 0.2849 | 0.0002 | 0.0000 | 0.0012 | 0.0004 | 0.0062 | 0.0042 | 0.0208 | 0.0156 | 0.0649 | 0.0540 | 0.0900 | 0.0828 | 0.0815 | 0.0608 | 0.1083 | 0.0905 | 0.6269 | 0.6917 | 0.0017 | 0.0008 | 0.0031 | 0.0078 | 0.0133 | 0.0090 | 0.0269 | 0.0377 | 0.0941 | 0.1099 | 0.1339 | 0.1333 | 0.0896 | 0.1005 | 0.1210 | 0.1255 | 0.5164 | 0.4754 | 0.0009 | 0.0028 | 0.0079 | 0.0247 | 0.0791 | 0.1123 | 0.0879 | 0.1140 | 0.5705 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 68 | 826 | | 4128 | 6864 | 146.8 | 44.75 | 144.31 | 126.93 | 100 | 110 | 118 | 127 | 136 | 147 | 160 | 181 | 211 | 0.1005 | 690 | 1.168 | 86.40 | 31.91 | 1 | 0.0540 | 223 | 0.0017 | 33.02 | 6.715 | 0.2229 | 23554.4 | 4140000 | 797000000 | 166000000000 | 0.3837 | 0.2702 | 0.0030 | 0.0000 | 0.0044 | 0.0000 | 0.0178 | 0.0020 | 0.0435 | 0.0054 | 0.1156 | 0.0363 | 0.1789 | 0.0632 | 0.1848 | 0.0697 | 0.1912 | 0.1133 | 0.2609 | 0.7102 | 0.0021 | 0.0000 | 0.0021 | 0.0000 | 0.0065 | 0.0008 | 0.0174 | 0.0018 | 0.0533 | 0.0206 | 0.0793 | 0.0323 | 0.0854 | 0.0354 | 0.1083 | 0.0652 | 0.6456 | 0.8440 | 0.0011 | 0.0066 | 0.0033 | 0.0087 | 0.0299 | 0.0175 | 0.0421 | 0.0611 | 0.0965 | 0.1332 | 0.1275 | 0.1681 | 0.0976 | 0.1201 | 0.1197 | 0.1638 | 0.4823 | 0.3210 | 0.0024 | 0.0042 | 0.0180 | 0.0342 | 0.0792 | 0.1104 | 0.0870 | 0.1309 | 0.5336 | 30 | 44 | 59 | 79 | 101 | 131 | 171 | 232 | 322 | 0.0037 | 48.50 | 6.480 | 0.3040 | 36934.0 | 13300000 | 5910000000 | 3030000000000 | 0.5053 | 0.1536 | 0.0289 | 0.0009 | 0.1252 | 0.0109 | 0.1753 | 0.0639 | 0.1667 | 0.0948 | 0.1830 | 0.1501 | 0.1532 | 0.1791 | 0.0886 | 0.1497 | 0.0559 | 0.1542 | 0.0231 | 0.1964 | 0.0016 | 0.0003 | 0.0026 | 0.0026 | 0.0078 | 0.0059 | 0.0260 | 0.0221 | 0.0809 | 0.0635 | 0.1135 | 0.0910 | 0.0891 | 0.0846 | 0.1135 | 0.1116 | 0.5650 | 0.6183 | 0.0020 | 0.0018 | 0.0025 | 0.0077 | 0.0088 | 0.0196 | 0.0471 | 0.0422 | 0.0972 | 0.1040 | 0.1290 | 0.1337 | 0.1035 | 0.1040 | 0.1295 | 0.1349 | 0.4804 | 0.4522 | 0.0000 | 0.0060 | 0.0116 | 0.0344 | 0.0800 | 0.1244 | 0.1000 | 0.1224 | 0.5214 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1110 | 560 | | 2334 | 4086 | 123.1 | 42.05 | 219.05 | 128.32 | 74 | 87 | 96 | 107 | 117 | 129 | 142 | 157 | 183 | 0.1216 | 497 | 1.080 | 108.23 | 35.38 | 1 | 0.1204 | 281 | 0.0009 | 90.87 | 7.214 | 0.1270 | 16914.4 | 2570000 | 424000000 | 75500000000 | 0.4870 | 0.1611 | 0.0000 | 0.0000 | 0.0062 | 0.0006 | 0.0503 | 0.0006 | 0.1077 | 0.0083 | 0.1877 | 0.0598 | 0.2236 | 0.1374 | 0.1549 | 0.1291 | 0.1251 | 0.1551 | 0.1446 | 0.5091 | 0.0000 | 0.0000 | 0.0013 | 0.0005 | 0.0013 | 0.0000 | 0.0139 | 0.0057 | 0.0606 | 0.0335 | 0.1205 | 0.0746 | 0.0833 | 0.0581 | 0.1091 | 0.0846 | 0.6101 | 0.7430 | 0.0016 | 0.0000 | 0.0049 | 0.0000 | 0.0148 | 0.0256 | 0.0590 | 0.1026 | 0.1426 | 0.1891 | 0.1672 | 0.1987 | 0.1344 | 0.1218 | 0.1656 | 0.1346 | 0.3098 | 0.2276 | 0.0000 | 0.0019 | 0.0104 | 0.0321 | 0.0888 | 0.1671 | 0.1048 | 0.1398 | 0.4551 | 74 | 103 | 134 | 163 | 195 | 230 | 276 | 327 | 396 | 0.0027 | 23.43 | 6.329 | 0.2976 | 64441.3 | 23200000 | 9650000000 | 4520000000000 | 0.5232 | 0.1346 | 0.0093 | 0.0010 | 0.0558 | 0.0031 | 0.1767 | 0.0135 | 0.1787 | 0.0556 | 0.1911 | 0.1329 | 0.1560 | 0.1989 | 0.1188 | 0.1848 | 0.0692 | 0.1776 | 0.0444 | 0.2326 | 0.0004 | 0.0003 | 0.0009 | 0.0007 | 0.0044 | 0.0031 | 0.0126 | 0.0097 | 0.0566 | 0.0384 | 0.1111 | 0.0746 | 0.0910 | 0.0695 | 0.1324 | 0.1126 | 0.5906 | 0.6911 | 0.0015 | 0.0041 | 0.0068 | 0.0021 | 0.0090 | 0.0155 | 0.0384 | 0.0671 | 0.1032 | 0.1405 | 0.1800 | 0.1736 | 0.1122 | 0.1395 | 0.1611 | 0.1736 | 0.3878 | 0.2841 | 0.0000 | 0.0023 | 0.0051 | 0.0277 | 0.0779 | 0.1429 | 0.1107 | 0.1440 | 0.4896 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 609 | 654 | | 7151 | 16942 | 197.2 | 47.67 | 158.72 | 128.62 | 142 | 158 | 169 | 180 | 191 | 204 | 217 | 235 | 262 | 0.0596 | 1009 | 1.165 | 114.14 | 40.26 | 1 | 0.0386 | 276 | 0.0010 | 44.53 | 7.179 | 0.1807 | 41154.1 | 9080000 | 2110000000 | 515000000000 | 0.4398 | 0.2146 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0034 | 0.0005 | 0.0225 | 0.0016 | 0.0918 | 0.0226 | 0.1658 | 0.0544 | 0.1623 | 0.0541 | 0.1830 | 0.0721 | 0.3699 | 0.7947 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0003 | 0.0087 | 0.0007 | 0.0377 | 0.0140 | 0.0650 | 0.0283 | 0.0655 | 0.0241 | 0.0987 | 0.0339 | 0.7223 | 0.8987 | 0.0043 | 0.0021 | 0.0080 | 0.0062 | 0.0217 | 0.0331 | 0.0810 | 0.1198 | 0.1389 | 0.1818 | 0.1975 | 0.2293 | 0.1172 | 0.1198 | 0.1404 | 0.1446 | 0.2909 | 0.1632 | 0.0015 | 0.0028 | 0.0067 | 0.0294 | 0.0781 | 0.1246 | 0.1136 | 0.1476 | 0.4957 | 29 | 50 | 73 | 98 | 124 | 154 | 195 | 255 | 340 | 0.0025 | 49.37 | 6.896 | 0.3087 | 41734.7 | 14900000 | 6570000000 | 3430000000000 | 0.4757 | 0.1683 | 0.0102 | 0.0005 | 0.0551 | 0.0051 | 0.1533 | 0.0172 | 0.1688 | 0.0526 | 0.1754 | 0.1321 | 0.1767 | 0.1793 | 0.1141 | 0.1494 | 0.0913 | 0.1597 | 0.0551 | 0.3041 | 0.0000 | 0.0002 | 0.0006 | 0.0008 | 0.0042 | 0.0018 | 0.0120 | 0.0073 | 0.0502 | 0.0359 | 0.0871 | 0.0632 | 0.0784 | 0.0546 | 0.1087 | 0.0842 | 0.6587 | 0.7522 | 0.0021 | 0.0007 | 0.0015 | 0.0035 | 0.0069 | 0.0106 | 0.0218 | 0.0308 | 0.0832 | 0.0946 | 0.1321 | 0.1464 | 0.1017 | 0.1114 | 0.1388 | 0.1415 | 0.5118 | 0.4604 | 0.0011 | 0.0012 | 0.0050 | 0.0180 | 0.0637 | 0.1167 | 0.0942 | 0.1257 | 0.5744 | ||
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 637 | 251 | | 4831 | 6157 | 434.9 | 144.34 | 87.99 | 128.76 | 226 | 293 | 353 | 413 | 455 | 489 | 520 | 554 | 622 | 0.1176 | 724 | 0.741 | 143.63 | 44.91 | 2 | 0.0909 | 439 | 0.0009 | 28.38 | 7.266 | 0.2359 | 209951.0 | 109000000 | 59200000000 | 33500000000000 | 0.3927 | 0.2352 | 0.0015 | 0.0000 | 0.0035 | 0.0000 | 0.0050 | 0.0003 | 0.0179 | 0.0042 | 0.0601 | 0.0282 | 0.1118 | 0.0434 | 0.0860 | 0.0299 | 0.1143 | 0.0511 | 0.5999 | 0.8429 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0002 | 0.0023 | 0.0022 | 0.0216 | 0.0210 | 0.0347 | 0.0259 | 0.0213 | 0.0213 | 0.0361 | 0.0291 | 0.8835 | 0.9002 | 0.0007 | 0.0000 | 0.0035 | 0.0000 | 0.0084 | 0.0000 | 0.0169 | 0.0000 | 0.0443 | 0.0000 | 0.0718 | 0.0000 | 0.0577 | 0.0000 | 0.0809 | 0.0000 | 0.7157 | 1.0000 | 0.0000 | 0.0007 | 0.0011 | 0.0048 | 0.0257 | 0.0432 | 0.0313 | 0.0555 | 0.8375 | 9 | 11 | 13 | 18 | 26 | 42 | 87 | 147 | 262 | 0.1247 | 11.17 | 3.769 | 0.6386 | 24317.8 | 10200000 | 5220000000 | 3080000000000 | 0.5729 | 0.1008 | 0.0398 | 0.0089 | 0.1273 | 0.0316 | 0.1777 | 0.0671 | 0.1751 | 0.0886 | 0.1565 | 0.1696 | 0.1008 | 0.1810 | 0.0955 | 0.1405 | 0.0822 | 0.1329 | 0.0451 | 0.1797 | 0.0005 | 0.0004 | 0.0020 | 0.0027 | 0.0025 | 0.0027 | 0.0094 | 0.0093 | 0.0480 | 0.0409 | 0.0762 | 0.0721 | 0.0574 | 0.0503 | 0.0826 | 0.0730 | 0.7216 | 0.7486 | 0.0000 | 0.0007 | 0.0018 | 0.0000 | 0.0030 | 0.0048 | 0.0152 | 0.0213 | 0.0626 | 0.0810 | 0.1027 | 0.1071 | 0.0699 | 0.1009 | 0.1240 | 0.1263 | 0.6207 | 0.5580 | 0.0000 | 0.0005 | 0.0016 | 0.0114 | 0.0565 | 0.0864 | 0.0549 | 0.1010 | 0.6877 |