High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 508 | 133 | | 5112 | 15953 | 596.9 | 122.93 | 209.99 | 332.25 | 447 | 490 | 521 | 552 | 585 | 617 | 653 | 698 | 767 | 0.0564 | 899 | 0.855 | 86.15 | 24.76 | 1 | 0.0428 | 219 | 0.0004 | 156.57 | 7.925 | 0.1053 | 371349.0 | 241000000 | 162000000000 | 113000000000000 | 0.4423 | 0.2051 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0187 | 0.0008 | 0.0672 | 0.0192 | 0.1466 | 0.0410 | 0.1398 | 0.0373 | 0.1694 | 0.0551 | 0.4551 | 0.8466 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0089 | 0.0004 | 0.0325 | 0.0132 | 0.0678 | 0.0246 | 0.0610 | 0.0151 | 0.0909 | 0.0305 | 0.7386 | 0.9162 | 0.0023 | 0.0043 | 0.0103 | 0.0043 | 0.0195 | 0.0468 | 0.0736 | 0.1319 | 0.1310 | 0.1872 | 0.2080 | 0.2468 | 0.1023 | 0.0936 | 0.1264 | 0.1106 | 0.3264 | 0.1745 | 0.0008 | 0.0025 | 0.0105 | 0.0257 | 0.0758 | 0.1281 | 0.1049 | 0.1184 | 0.5333 | 8 | 10 | 12 | 14 | 20 | 73 | 208 | 417 | 696 | 0.1770 | 37.47 | 4.561 | 0.5961 | 154477.0 | 156000000 | 189000000000 | 260000000000000 | 0.5567 | 0.1171 | 0.0435 | 0.0017 | 0.1317 | 0.0133 | 0.1719 | 0.0920 | 0.1462 | 0.1123 | 0.1551 | 0.1516 | 0.1272 | 0.1707 | 0.1071 | 0.1244 | 0.0737 | 0.1291 | 0.0435 | 0.2049 | 0.0000 | 0.0003 | 0.0002 | 0.0000 | 0.0013 | 0.0010 | 0.0089 | 0.0045 | 0.0312 | 0.0322 | 0.0618 | 0.0501 | 0.0532 | 0.0353 | 0.0709 | 0.0694 | 0.7724 | 0.8070 | 0.0005 | 0.0002 | 0.0000 | 0.0007 | 0.0023 | 0.0015 | 0.0087 | 0.0100 | 0.0449 | 0.0500 | 0.0795 | 0.0826 | 0.0525 | 0.0585 | 0.0887 | 0.0933 | 0.7230 | 0.7032 | 0.0008 | 0.0015 | 0.0023 | 0.0088 | 0.0390 | 0.0736 | 0.0524 | 0.0793 | 0.7423 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1019 | 349 | | 9618 | 24025 | 311.2 | 60.78 | 47.50 | 70.92 | 239 | 262 | 278 | 292 | 306 | 319 | 335 | 359 | 394 | 0.0434 | 1042 | 1.091 | 135.98 | 39.60 | 1 | 0.0332 | 319 | 0.0011 | 37.84 | 7.134 | 0.1930 | 100552.0 | 33700000 | 11700000000 | 4210000000000 | 0.4073 | 0.2422 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0003 | 0.0111 | 0.0010 | 0.0488 | 0.0155 | 0.1086 | 0.0334 | 0.1075 | 0.0315 | 0.1452 | 0.0497 | 0.5765 | 0.8685 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0038 | 0.0000 | 0.0227 | 0.0104 | 0.0535 | 0.0216 | 0.0482 | 0.0135 | 0.0715 | 0.0245 | 0.7995 | 0.9301 | 0.0041 | 0.0134 | 0.0054 | 0.0107 | 0.0277 | 0.0321 | 0.0548 | 0.1417 | 0.1346 | 0.2139 | 0.1623 | 0.1658 | 0.1183 | 0.1604 | 0.1332 | 0.1203 | 0.3597 | 0.1417 | 0.0011 | 0.0068 | 0.0128 | 0.0344 | 0.0831 | 0.1137 | 0.0986 | 0.1283 | 0.5212 | 5 | 7 | 9 | 11 | 17 | 26 | 42 | 70 | 135 | 0.1095 | 3.91 | 3.513 | 0.6301 | 7285.7 | 1790000 | 547000000 | 191000000000 | 0.5936 | 0.0921 | 0.0466 | 0.0069 | 0.1372 | 0.0212 | 0.2066 | 0.0876 | 0.1884 | 0.1127 | 0.1803 | 0.1715 | 0.1165 | 0.1811 | 0.0547 | 0.1403 | 0.0461 | 0.1361 | 0.0238 | 0.1425 | 0.0015 | 0.0021 | 0.0025 | 0.0023 | 0.0037 | 0.0061 | 0.0203 | 0.0169 | 0.0582 | 0.0512 | 0.0902 | 0.0758 | 0.0689 | 0.0641 | 0.0942 | 0.0917 | 0.6606 | 0.6898 | 0.0012 | 0.0004 | 0.0019 | 0.0039 | 0.0074 | 0.0049 | 0.0223 | 0.0239 | 0.0738 | 0.0853 | 0.1163 | 0.1198 | 0.0743 | 0.0803 | 0.1070 | 0.1161 | 0.5957 | 0.5655 | 0.0003 | 0.0022 | 0.0054 | 0.0213 | 0.0700 | 0.0966 | 0.0734 | 0.1075 | 0.6233 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 538 | 522 | | 10143 | 24967 | 137.2 | 45.41 | 180.80 | 230.55 | 91 | 101 | 110 | 118 | 127 | 137 | 150 | 167 | 198 | 0.0470 | 1173 | 0.400 | 194.49 | 33.54 | 5 | 0.0550 | 558 | 0.0019 | 26.27 | 6.724 | 0.2500 | 20883.8 | 3560000 | 679000000 | 145000000000 | 0.4664 | 0.1883 | 0.0012 | 0.0001 | 0.0036 | 0.0001 | 0.0091 | 0.0012 | 0.0383 | 0.0057 | 0.1113 | 0.0305 | 0.1764 | 0.0645 | 0.1603 | 0.0659 | 0.1744 | 0.0958 | 0.3255 | 0.7361 | 0.0007 | 0.0001 | 0.0021 | 0.0001 | 0.0034 | 0.0007 | 0.0142 | 0.0028 | 0.0411 | 0.0161 | 0.0774 | 0.0311 | 0.0693 | 0.0286 | 0.0908 | 0.0446 | 0.7011 | 0.8759 | 0.0032 | 0.0009 | 0.0055 | 0.0026 | 0.0120 | 0.0205 | 0.0443 | 0.0759 | 0.1061 | 0.1253 | 0.1513 | 0.1748 | 0.1070 | 0.1228 | 0.1402 | 0.1313 | 0.4304 | 0.3461 | 0.0022 | 0.0049 | 0.0080 | 0.0279 | 0.0670 | 0.1061 | 0.0989 | 0.1234 | 0.5616 | 11 | 13 | 17 | 26 | 61 | 137 | 226 | 346 | 527 | 0.0541 | 38.24 | 5.495 | 0.4994 | 85842.1 | 54700000 | 40900000000 | 34200000000000 | 0.5806 | 0.1163 | 0.0514 | 0.0037 | 0.1686 | 0.0204 | 0.2152 | 0.1049 | 0.1551 | 0.1368 | 0.1378 | 0.1772 | 0.1287 | 0.1802 | 0.0730 | 0.1206 | 0.0476 | 0.1111 | 0.0226 | 0.1450 | 0.0004 | 0.0003 | 0.0008 | 0.0002 | 0.0017 | 0.0011 | 0.0086 | 0.0061 | 0.0487 | 0.0419 | 0.0930 | 0.0753 | 0.0691 | 0.0562 | 0.0965 | 0.0845 | 0.6812 | 0.7344 | 0.0005 | 0.0003 | 0.0014 | 0.0013 | 0.0031 | 0.0041 | 0.0161 | 0.0199 | 0.0661 | 0.0733 | 0.1165 | 0.1280 | 0.0805 | 0.0882 | 0.1160 | 0.1179 | 0.5998 | 0.5670 | 0.0002 | 0.0007 | 0.0022 | 0.0128 | 0.0574 | 0.1049 | 0.0737 | 0.1099 | 0.6383 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 854 | 405 | | 7527 | 31665 | 388.4 | 72.66 | 93.45 | 141.02 | 301 | 326 | 347 | 364 | 382 | 400 | 421 | 447 | 487 | 0.0374 | 1185 | 1.088 | 108.58 | 28.32 | 1 | 0.0323 | 243 | 0.0008 | 48.68 | 7.360 | 0.1631 | 156148.0 | 64900000 | 27900000000 | 12400000000000 | 0.4021 | 0.2480 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0046 | 0.0001 | 0.0110 | 0.0014 | 0.0414 | 0.0136 | 0.1010 | 0.0353 | 0.0993 | 0.0248 | 0.1508 | 0.0388 | 0.5912 | 0.8859 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0001 | 0.0052 | 0.0005 | 0.0195 | 0.0099 | 0.0510 | 0.0234 | 0.0462 | 0.0107 | 0.0737 | 0.0159 | 0.8031 | 0.9394 | 0.0056 | 0.0138 | 0.0130 | 0.0826 | 0.0241 | 0.0872 | 0.0519 | 0.1193 | 0.1270 | 0.1560 | 0.1724 | 0.2294 | 0.1233 | 0.0917 | 0.1483 | 0.0734 | 0.3346 | 0.1468 | 0.0008 | 0.0025 | 0.0065 | 0.0239 | 0.0686 | 0.1113 | 0.0975 | 0.1231 | 0.5659 | 6 | 8 | 11 | 21 | 39 | 63 | 99 | 156 | 250 | 0.0635 | 9.53 | 4.513 | 0.5426 | 28619.4 | 17100000 | 15800000000 | 18600000000000 | 0.4450 | 0.1844 | 0.0328 | 0.0005 | 0.1395 | 0.0088 | 0.2204 | 0.0603 | 0.1624 | 0.1175 | 0.1549 | 0.1747 | 0.1262 | 0.2022 | 0.0836 | 0.1486 | 0.0471 | 0.1229 | 0.0331 | 0.1645 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0022 | 0.0027 | 0.0119 | 0.0124 | 0.0537 | 0.0399 | 0.0815 | 0.0673 | 0.0674 | 0.0542 | 0.0954 | 0.0807 | 0.6869 | 0.7423 | 0.0007 | 0.0007 | 0.0017 | 0.0008 | 0.0046 | 0.0050 | 0.0176 | 0.0205 | 0.0658 | 0.0826 | 0.1195 | 0.1283 | 0.0762 | 0.0818 | 0.1160 | 0.1209 | 0.5979 | 0.5594 | 0.0003 | 0.0015 | 0.0051 | 0.0174 | 0.0607 | 0.0986 | 0.0754 | 0.1077 | 0.6333 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 343 | 118 | | 16901 | 26398 | 141.3 | 44.30 | 218.23 | 252.21 | 94 | 105 | 114 | 123 | 132 | 143 | 157 | 175 | 204 | 0.0815 | 2151 | 0.681 | 101.95 | 26.17 | 6 | 0.0180 | 304 | 0.0015 | 29.37 | 6.914 | 0.2233 | 21941.5 | 3740000 | 696000000 | 140000000000 | 0.5305 | 0.1501 | 0.0011 | 0.0003 | 0.0048 | 0.0008 | 0.0158 | 0.0020 | 0.0410 | 0.0075 | 0.1072 | 0.0328 | 0.1650 | 0.0728 | 0.1666 | 0.0720 | 0.1890 | 0.1025 | 0.3095 | 0.7093 | 0.0006 | 0.0002 | 0.0026 | 0.0004 | 0.0058 | 0.0011 | 0.0146 | 0.0036 | 0.0408 | 0.0175 | 0.0693 | 0.0366 | 0.0679 | 0.0300 | 0.0954 | 0.0486 | 0.7030 | 0.8620 | 0.0021 | 0.0030 | 0.0070 | 0.0090 | 0.0120 | 0.0200 | 0.0527 | 0.0656 | 0.1020 | 0.1512 | 0.1411 | 0.1773 | 0.1049 | 0.1097 | 0.1331 | 0.1607 | 0.4451 | 0.3035 | 0.0015 | 0.0049 | 0.0131 | 0.0289 | 0.0754 | 0.1125 | 0.0940 | 0.1202 | 0.5495 | 20 | 29 | 48 | 79 | 120 | 175 | 259 | 375 | 570 | 0.0118 | 66.19 | 6.470 | 0.3644 | 111232.0 | 85900000 | 88000000000 | 113000000000000 | 0.5942 | 0.0903 | 0.0589 | 0.0022 | 0.1898 | 0.0187 | 0.2385 | 0.1095 | 0.1625 | 0.1457 | 0.1298 | 0.1893 | 0.1051 | 0.1818 | 0.0549 | 0.1192 | 0.0407 | 0.1100 | 0.0196 | 0.1236 | 0.0006 | 0.0005 | 0.0022 | 0.0016 | 0.0043 | 0.0051 | 0.0185 | 0.0152 | 0.0708 | 0.0630 | 0.1147 | 0.0979 | 0.0818 | 0.0754 | 0.1208 | 0.1064 | 0.5863 | 0.6349 | 0.0003 | 0.0018 | 0.0031 | 0.0043 | 0.0077 | 0.0110 | 0.0323 | 0.0372 | 0.0907 | 0.0969 | 0.1399 | 0.1479 | 0.1021 | 0.1013 | 0.1285 | 0.1341 | 0.4956 | 0.4656 | 0.0010 | 0.0025 | 0.0059 | 0.0245 | 0.0763 | 0.1324 | 0.0895 | 0.1228 | 0.5449 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 110 | 146 | | 3370 | 10890 | 147.0 | 47.54 | 205.95 | 210.52 | 96 | 109 | 120 | 130 | 141 | 152 | 166 | 184 | 210 | 0.0687 | 748 | 0.698 | 87.82 | 16.12 | 1 | 0.0591 | 199 | 0.0013 | 45.70 | 6.937 | 0.1972 | 23872.7 | 4240000 | 821000000 | 172000000000 | 0.4754 | 0.1834 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0213 | 0.0022 | 0.0640 | 0.0076 | 0.1469 | 0.0404 | 0.2133 | 0.0913 | 0.1633 | 0.0822 | 0.1664 | 0.1230 | 0.2176 | 0.6533 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0021 | 0.0003 | 0.0144 | 0.0026 | 0.0499 | 0.0204 | 0.0960 | 0.0459 | 0.0828 | 0.0328 | 0.1240 | 0.0548 | 0.6288 | 0.8431 | 0.0013 | 0.0000 | 0.0038 | 0.0233 | 0.0115 | 0.0465 | 0.0712 | 0.0930 | 0.1387 | 0.1964 | 0.2010 | 0.1783 | 0.1221 | 0.1163 | 0.1425 | 0.1370 | 0.3079 | 0.2093 | 0.0000 | 0.0026 | 0.0073 | 0.0389 | 0.0956 | 0.1404 | 0.1107 | 0.1325 | 0.4720 | 20 | 29 | 54 | 89 | 136 | 193 | 264 | 354 | 501 | 0.0118 | 65.86 | 6.461 | 0.3264 | 86732.2 | 51500000 | 38400000000 | 34300000000000 | 0.4942 | 0.1738 | 0.0577 | 0.0022 | 0.1982 | 0.0147 | 0.2589 | 0.0932 | 0.1590 | 0.1398 | 0.1250 | 0.1746 | 0.0895 | 0.1735 | 0.0643 | 0.1315 | 0.0348 | 0.1305 | 0.0126 | 0.1401 | 0.0006 | 0.0002 | 0.0021 | 0.0007 | 0.0027 | 0.0018 | 0.0144 | 0.0103 | 0.0681 | 0.0533 | 0.1264 | 0.0962 | 0.0930 | 0.0790 | 0.1328 | 0.1098 | 0.5599 | 0.6487 | 0.0006 | 0.0017 | 0.0011 | 0.0058 | 0.0108 | 0.0178 | 0.0354 | 0.0463 | 0.1058 | 0.1014 | 0.1580 | 0.1570 | 0.1044 | 0.1056 | 0.1298 | 0.1395 | 0.4541 | 0.4249 | 0.0000 | 0.0012 | 0.0063 | 0.0167 | 0.0951 | 0.1417 | 0.1103 | 0.1347 | 0.4942 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1179 | 189 | | 16382 | 26563 | 119.9 | 50.77 | 96.33 | 96.08 | 57 | 80 | 93 | 105 | 115 | 128 | 142 | 159 | 186 | 0.0652 | 1732 | 0.279 | 134.45 | 18.44 | 8 | 0.0245 | 401 | 0.0012 | 34.16 | 7.111 | 0.2279 | 16954.2 | 2720000 | 485000000 | 94900000000 | 0.4885 | 0.1704 | 0.0014 | 0.0001 | 0.0069 | 0.0005 | 0.0266 | 0.0024 | 0.0715 | 0.0104 | 0.1597 | 0.0480 | 0.2113 | 0.0993 | 0.1753 | 0.1092 | 0.1597 | 0.1428 | 0.1876 | 0.5873 | 0.0004 | 0.0001 | 0.0017 | 0.0003 | 0.0033 | 0.0012 | 0.0102 | 0.0037 | 0.0386 | 0.0208 | 0.0699 | 0.0357 | 0.0674 | 0.0386 | 0.0962 | 0.0530 | 0.7123 | 0.8467 | 0.0017 | 0.0038 | 0.0051 | 0.0091 | 0.0110 | 0.0152 | 0.0442 | 0.0800 | 0.1188 | 0.1523 | 0.1512 | 0.1789 | 0.1184 | 0.1144 | 0.1491 | 0.1413 | 0.4006 | 0.3050 | 0.0009 | 0.0013 | 0.0058 | 0.0245 | 0.0728 | 0.1185 | 0.1037 | 0.1302 | 0.5422 | 15 | 22 | 32 | 46 | 64 | 86 | 117 | 158 | 222 | 0.0165 | 11.29 | 5.277 | 0.4716 | 18511.3 | 5390000 | 2090000000 | 994000000000 | 0.5640 | 0.1104 | 0.0416 | 0.0021 | 0.1298 | 0.0145 | 0.2417 | 0.0717 | 0.1786 | 0.1322 | 0.1563 | 0.1705 | 0.1056 | 0.1818 | 0.0805 | 0.1400 | 0.0452 | 0.1272 | 0.0207 | 0.1600 | 0.0013 | 0.0006 | 0.0026 | 0.0025 | 0.0052 | 0.0043 | 0.0226 | 0.0158 | 0.0717 | 0.0537 | 0.1141 | 0.0969 | 0.0904 | 0.0786 | 0.1320 | 0.1170 | 0.5601 | 0.6307 | 0.0017 | 0.0015 | 0.0030 | 0.0031 | 0.0089 | 0.0133 | 0.0324 | 0.0402 | 0.0970 | 0.1132 | 0.1484 | 0.1592 | 0.1051 | 0.1113 | 0.1413 | 0.1490 | 0.4622 | 0.4093 | 0.0015 | 0.0038 | 0.0079 | 0.0238 | 0.0829 | 0.1287 | 0.1026 | 0.1362 | 0.5125 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 804 | 192 | | 9922 | 14775 | 134.6 | 40.27 | 276.51 | 259.87 | 90 | 102 | 111 | 120 | 129 | 139 | 151 | 165 | 185 | 0.0923 | 1363 | 0.678 | 210.00 | 48.17 | 5 | 0.0555 | 551 | 0.0016 | 25.40 | 6.776 | 0.2333 | 19732.5 | 3150000 | 551000000 | 105000000000 | 0.4834 | 0.1711 | 0.0002 | 0.0002 | 0.0017 | 0.0006 | 0.0103 | 0.0011 | 0.0422 | 0.0040 | 0.1105 | 0.0312 | 0.1807 | 0.0675 | 0.1790 | 0.0732 | 0.1797 | 0.1114 | 0.2958 | 0.7108 | 0.0000 | 0.0001 | 0.0008 | 0.0005 | 0.0029 | 0.0007 | 0.0109 | 0.0020 | 0.0409 | 0.0198 | 0.0753 | 0.0371 | 0.0711 | 0.0313 | 0.0968 | 0.0504 | 0.7013 | 0.8580 | 0.0027 | 0.0123 | 0.0096 | 0.0212 | 0.0183 | 0.0368 | 0.0636 | 0.0982 | 0.1208 | 0.1618 | 0.1707 | 0.1696 | 0.1304 | 0.1027 | 0.1405 | 0.1395 | 0.3432 | 0.2578 | 0.0009 | 0.0023 | 0.0100 | 0.0275 | 0.0776 | 0.1327 | 0.1116 | 0.1316 | 0.5059 | 27 | 54 | 105 | 157 | 206 | 265 | 334 | 441 | 628 | 0.0057 | 57.11 | 6.881 | 0.3026 | 143987.0 | 105000000 | 93700000000 | 95000000000000 | 0.6013 | 0.0968 | 0.0216 | 0.0014 | 0.0960 | 0.0083 | 0.1877 | 0.0540 | 0.1629 | 0.0789 | 0.1693 | 0.1505 | 0.1733 | 0.1848 | 0.0968 | 0.1576 | 0.0464 | 0.1582 | 0.0460 | 0.2061 | 0.0006 | 0.0002 | 0.0016 | 0.0005 | 0.0059 | 0.0036 | 0.0231 | 0.0129 | 0.0764 | 0.0640 | 0.1265 | 0.1009 | 0.0993 | 0.0832 | 0.1089 | 0.1172 | 0.5577 | 0.6175 | 0.0025 | 0.0011 | 0.0056 | 0.0083 | 0.0181 | 0.0174 | 0.0350 | 0.0365 | 0.0934 | 0.0970 | 0.1313 | 0.1352 | 0.0834 | 0.0918 | 0.1084 | 0.1086 | 0.5223 | 0.5041 | 0.0012 | 0.0041 | 0.0118 | 0.0325 | 0.0905 | 0.1330 | 0.0907 | 0.1109 | 0.5253 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 821 | 296 | | 10441 | 19427 | 121.6 | 37.86 | 144.94 | 161.51 | 79 | 90 | 99 | 108 | 116 | 126 | 138 | 153 | 174 | 0.0627 | 1218 | 0.254 | 218.68 | 45.79 | 4 | 0.0876 | 915 | 0.0020 | 18.42 | 6.592 | 0.2752 | 16229.4 | 2350000 | 367000000 | 61000000000 | 0.4705 | 0.1773 | 0.0012 | 0.0001 | 0.0034 | 0.0006 | 0.0120 | 0.0011 | 0.0412 | 0.0074 | 0.1063 | 0.0358 | 0.1638 | 0.0724 | 0.1588 | 0.0758 | 0.1756 | 0.1072 | 0.3378 | 0.6997 | 0.0007 | 0.0001 | 0.0015 | 0.0001 | 0.0029 | 0.0005 | 0.0135 | 0.0023 | 0.0368 | 0.0171 | 0.0641 | 0.0363 | 0.0621 | 0.0302 | 0.0774 | 0.0464 | 0.7412 | 0.8670 | 0.0044 | 0.0067 | 0.0016 | 0.0117 | 0.0148 | 0.0341 | 0.0487 | 0.0908 | 0.0907 | 0.1341 | 0.1362 | 0.1882 | 0.1286 | 0.1440 | 0.1354 | 0.1440 | 0.4395 | 0.2465 | 0.0006 | 0.0041 | 0.0103 | 0.0299 | 0.0638 | 0.1050 | 0.0907 | 0.1158 | 0.5798 | 11 | 14 | 20 | 40 | 78 | 132 | 194 | 273 | 378 | 0.0407 | 25.51 | 5.518 | 0.4667 | 47091.3 | 20600000 | 10800000000 | 6430000000000 | 0.5620 | 0.1280 | 0.0686 | 0.0021 | 0.1796 | 0.0256 | 0.2678 | 0.1420 | 0.1409 | 0.1373 | 0.1146 | 0.1747 | 0.0965 | 0.1718 | 0.0578 | 0.1136 | 0.0428 | 0.1049 | 0.0315 | 0.1281 | 0.0001 | 0.0004 | 0.0010 | 0.0007 | 0.0020 | 0.0019 | 0.0094 | 0.0061 | 0.0535 | 0.0466 | 0.1056 | 0.0854 | 0.0759 | 0.0627 | 0.1166 | 0.0964 | 0.6358 | 0.6997 | 0.0008 | 0.0011 | 0.0017 | 0.0029 | 0.0042 | 0.0088 | 0.0152 | 0.0241 | 0.0795 | 0.0957 | 0.1485 | 0.1575 | 0.0994 | 0.1066 | 0.1429 | 0.1449 | 0.5079 | 0.4585 | 0.0003 | 0.0016 | 0.0031 | 0.0113 | 0.0700 | 0.1221 | 0.0927 | 0.1315 | 0.5675 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 262 | 293 | | 4620 | 9068 | 125.3 | 34.05 | 229.46 | 230.57 | 87 | 97 | 105 | 113 | 120 | 129 | 139 | 150 | 170 | 0.0786 | 713 | 0.960 | 89.94 | 24.74 | 1 | 0.0455 | 210 | 0.0019 | 28.55 | 6.554 | 0.2287 | 16849.6 | 2440000 | 379000000 | 63400000000 | 0.4415 | 0.2073 | 0.0011 | 0.0000 | 0.0034 | 0.0000 | 0.0134 | 0.0020 | 0.0550 | 0.0044 | 0.1237 | 0.0285 | 0.1753 | 0.0668 | 0.1760 | 0.0717 | 0.1955 | 0.1060 | 0.2566 | 0.7207 | 0.0003 | 0.0000 | 0.0014 | 0.0000 | 0.0025 | 0.0002 | 0.0129 | 0.0016 | 0.0525 | 0.0172 | 0.0784 | 0.0347 | 0.0865 | 0.0293 | 0.1231 | 0.0528 | 0.6423 | 0.8643 | 0.0053 | 0.0075 | 0.0149 | 0.0151 | 0.0351 | 0.0327 | 0.0904 | 0.1332 | 0.1521 | 0.2010 | 0.1883 | 0.2161 | 0.1223 | 0.1156 | 0.1383 | 0.1231 | 0.2532 | 0.1558 | 0.0024 | 0.0043 | 0.0097 | 0.0454 | 0.0985 | 0.1424 | 0.1318 | 0.1544 | 0.4112 | 25 | 41 | 69 | 102 | 141 | 203 | 283 | 398 | 568 | 0.0094 | 60.31 | 6.466 | 0.3430 | 105806.0 | 66900000 | 50200000000 | 42000000000000 | 0.4589 | 0.1675 | 0.0392 | 0.0005 | 0.1446 | 0.0095 | 0.2500 | 0.0695 | 0.1940 | 0.1304 | 0.1567 | 0.1823 | 0.1063 | 0.1972 | 0.0653 | 0.1403 | 0.0336 | 0.1173 | 0.0103 | 0.1530 | 0.0003 | 0.0002 | 0.0005 | 0.0022 | 0.0021 | 0.0028 | 0.0152 | 0.0130 | 0.0627 | 0.0430 | 0.0970 | 0.0745 | 0.0807 | 0.0682 | 0.1031 | 0.0917 | 0.6385 | 0.7043 | 0.0000 | 0.0004 | 0.0036 | 0.0013 | 0.0053 | 0.0101 | 0.0246 | 0.0331 | 0.0891 | 0.0947 | 0.1162 | 0.1404 | 0.1023 | 0.1086 | 0.1276 | 0.1379 | 0.5314 | 0.4736 | 0.0015 | 0.0024 | 0.0037 | 0.0198 | 0.0678 | 0.1110 | 0.0916 | 0.1199 | 0.5823 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 401 | 465 | | 5688 | 21468 | 395.0 | 83.99 | 124.18 | 239.02 | 290 | 326 | 352 | 373 | 392 | 410 | 430 | 457 | 504 | 0.0522 | 1120 | 1.175 | 146.10 | 54.92 | 1 | 0.0647 | 368 | 0.0007 | 85.77 | 7.563 | 0.1400 | 163082.0 | 70200000 | 31500000000 | 14700000000000 | 0.4503 | 0.2076 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0036 | 0.0000 | 0.0145 | 0.0009 | 0.0614 | 0.0220 | 0.1338 | 0.0403 | 0.1196 | 0.0438 | 0.1527 | 0.0645 | 0.5131 | 0.8284 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0036 | 0.0004 | 0.0302 | 0.0151 | 0.0598 | 0.0258 | 0.0550 | 0.0211 | 0.0858 | 0.0337 | 0.7648 | 0.9040 | 0.0011 | 0.0168 | 0.0078 | 0.0294 | 0.0343 | 0.0546 | 0.0676 | 0.1723 | 0.1495 | 0.1765 | 0.2137 | 0.2185 | 0.0952 | 0.0840 | 0.1384 | 0.0840 | 0.2924 | 0.1639 | 0.0018 | 0.0025 | 0.0094 | 0.0305 | 0.0864 | 0.1409 | 0.1097 | 0.1543 | 0.4644 | 7 | 8 | 9 | 11 | 13 | 19 | 59 | 166 | 460 | 0.2326 | 28.31 | 3.763 | 0.6555 | 72548.9 | 59000000 | 55500000000 | 57500000000000 | 0.4057 | 0.2332 | 0.0627 | 0.0034 | 0.2304 | 0.0282 | 0.2413 | 0.1477 | 0.1242 | 0.1167 | 0.1363 | 0.1635 | 0.0893 | 0.1860 | 0.0555 | 0.1037 | 0.0483 | 0.1020 | 0.0121 | 0.1488 | 0.0000 | 0.0002 | 0.0002 | 0.0000 | 0.0007 | 0.0015 | 0.0069 | 0.0057 | 0.0502 | 0.0393 | 0.0700 | 0.0667 | 0.0470 | 0.0434 | 0.0722 | 0.0667 | 0.7528 | 0.7766 | 0.0000 | 0.0002 | 0.0007 | 0.0007 | 0.0015 | 0.0021 | 0.0071 | 0.0088 | 0.0563 | 0.0601 | 0.0801 | 0.0852 | 0.0541 | 0.0560 | 0.0781 | 0.0805 | 0.7221 | 0.7063 | 0.0000 | 0.0000 | 0.0024 | 0.0088 | 0.0529 | 0.0768 | 0.0489 | 0.0729 | 0.7373 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 700 | | 12030 | 35050 | 359.5 | 76.99 | 172.29 | 212.34 | 266 | 289 | 311 | 331 | 350 | 372 | 398 | 428 | 469 | 0.0370 | 1298 | 1.080 | 120.07 | 37.70 | 1 | 0.0246 | 296 | 0.0007 | 42.37 | 7.437 | 0.1770 | 135186.0 | 53100000 | 21700000000 | 9200000000000 | 0.4257 | 0.2254 | 0.0007 | 0.0000 | 0.0024 | 0.0001 | 0.0047 | 0.0001 | 0.0166 | 0.0019 | 0.0578 | 0.0130 | 0.1117 | 0.0286 | 0.1278 | 0.0293 | 0.1729 | 0.0489 | 0.5054 | 0.8782 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0021 | 0.0000 | 0.0074 | 0.0004 | 0.0263 | 0.0079 | 0.0509 | 0.0166 | 0.0541 | 0.0114 | 0.0771 | 0.0203 | 0.7814 | 0.9434 | 0.0031 | 0.0144 | 0.0096 | 0.0431 | 0.0206 | 0.0431 | 0.0477 | 0.1150 | 0.0984 | 0.1889 | 0.1164 | 0.1725 | 0.1067 | 0.1376 | 0.1474 | 0.1212 | 0.4501 | 0.1643 | 0.0022 | 0.0027 | 0.0087 | 0.0265 | 0.0634 | 0.0961 | 0.0890 | 0.1053 | 0.6061 | 8 | 10 | 16 | 35 | 74 | 134 | 219 | 336 | 490 | 0.0515 | 30.59 | 5.525 | 0.4509 | 74768.6 | 43400000 | 30000000000 | 23500000000000 | 0.4088 | 0.2228 | 0.0812 | 0.0029 | 0.2274 | 0.0275 | 0.2491 | 0.1801 | 0.1201 | 0.1627 | 0.1228 | 0.1764 | 0.0750 | 0.1525 | 0.0533 | 0.1018 | 0.0392 | 0.0801 | 0.0320 | 0.1161 | 0.0001 | 0.0001 | 0.0002 | 0.0004 | 0.0010 | 0.0009 | 0.0095 | 0.0074 | 0.0610 | 0.0504 | 0.1018 | 0.0884 | 0.0671 | 0.0617 | 0.1083 | 0.0895 | 0.6509 | 0.7012 | 0.0002 | 0.0002 | 0.0005 | 0.0005 | 0.0022 | 0.0037 | 0.0162 | 0.0203 | 0.0769 | 0.0888 | 0.1277 | 0.1338 | 0.0832 | 0.0898 | 0.1251 | 0.1318 | 0.5682 | 0.5312 | 0.0003 | 0.0002 | 0.0015 | 0.0144 | 0.0678 | 0.1109 | 0.0804 | 0.1157 | 0.6087 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 599 | 374 | | 6551 | 17041 | 267.6 | 66.19 | 105.49 | 114.89 | 194 | 211 | 226 | 241 | 255 | 271 | 293 | 319 | 363 | 0.0596 | 1016 | 1.053 | 98.33 | 35.17 | 1 | 0.0400 | 262 | 0.0008 | 56.30 | 7.438 | 0.1617 | 75974.1 | 22900000 | 7350000000 | 2490000000000 | 0.4000 | 0.2484 | 0.0008 | 0.0000 | 0.0034 | 0.0003 | 0.0047 | 0.0005 | 0.0238 | 0.0032 | 0.0663 | 0.0219 | 0.1305 | 0.0441 | 0.1370 | 0.0413 | 0.1859 | 0.0657 | 0.4477 | 0.8230 | 0.0004 | 0.0000 | 0.0022 | 0.0000 | 0.0022 | 0.0000 | 0.0124 | 0.0008 | 0.0271 | 0.0139 | 0.0574 | 0.0225 | 0.0594 | 0.0169 | 0.0936 | 0.0300 | 0.7454 | 0.9159 | 0.0048 | 0.0079 | 0.0072 | 0.0099 | 0.0183 | 0.0217 | 0.0462 | 0.0791 | 0.0916 | 0.1462 | 0.1371 | 0.1798 | 0.1139 | 0.1146 | 0.1394 | 0.1462 | 0.4414 | 0.2945 | 0.0018 | 0.0029 | 0.0058 | 0.0282 | 0.0762 | 0.1181 | 0.0986 | 0.1203 | 0.5482 | 12 | 15 | 20 | 33 | 58 | 96 | 143 | 192 | 256 | 0.0374 | 9.37 | 5.007 | 0.5330 | 24326.7 | 7980000 | 3300000000 | 1610000000000 | 0.5431 | 0.1194 | 0.0353 | 0.0003 | 0.2286 | 0.0100 | 0.3382 | 0.1134 | 0.1429 | 0.1621 | 0.1127 | 0.2268 | 0.0793 | 0.2001 | 0.0390 | 0.1222 | 0.0157 | 0.0806 | 0.0082 | 0.0845 | 0.0001 | 0.0000 | 0.0003 | 0.0005 | 0.0014 | 0.0004 | 0.0096 | 0.0081 | 0.0557 | 0.0459 | 0.1000 | 0.0861 | 0.0671 | 0.0552 | 0.0956 | 0.0849 | 0.6703 | 0.7189 | 0.0002 | 0.0006 | 0.0016 | 0.0026 | 0.0019 | 0.0060 | 0.0157 | 0.0227 | 0.0714 | 0.0843 | 0.1314 | 0.1389 | 0.0812 | 0.0897 | 0.1127 | 0.1180 | 0.5839 | 0.5372 | 0.0002 | 0.0008 | 0.0031 | 0.0103 | 0.0642 | 0.1150 | 0.0771 | 0.1071 | 0.6223 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1011 | 503 | | 8099 | 27715 | 207.4 | 49.29 | 90.32 | 133.45 | 151 | 164 | 175 | 187 | 199 | 212 | 228 | 248 | 276 | 0.0437 | 1212 | 1.109 | 152.01 | 45.19 | 2 | 0.0436 | 353 | 0.0011 | 36.08 | 7.089 | 0.1990 | 45423.4 | 10500000 | 2560000000 | 657000000000 | 0.4089 | 0.2364 | 0.0004 | 0.0000 | 0.0023 | 0.0001 | 0.0071 | 0.0004 | 0.0235 | 0.0021 | 0.0760 | 0.0188 | 0.1336 | 0.0422 | 0.1525 | 0.0391 | 0.1806 | 0.0611 | 0.4239 | 0.8362 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0001 | 0.0108 | 0.0006 | 0.0290 | 0.0107 | 0.0546 | 0.0216 | 0.0625 | 0.0137 | 0.0784 | 0.0235 | 0.7599 | 0.9297 | 0.0031 | 0.0101 | 0.0081 | 0.0067 | 0.0219 | 0.0236 | 0.0663 | 0.0809 | 0.1006 | 0.1720 | 0.1644 | 0.1585 | 0.1294 | 0.1282 | 0.1413 | 0.1619 | 0.3650 | 0.2580 | 0.0019 | 0.0022 | 0.0111 | 0.0259 | 0.0674 | 0.1078 | 0.1033 | 0.1236 | 0.5567 | 7 | 8 | 10 | 11 | 15 | 35 | 93 | 181 | 284 | 0.1964 | 12.37 | 4.050 | 0.6366 | 25966.7 | 10500000 | 5130000000 | 2920000000000 | 0.4760 | 0.1582 | 0.0839 | 0.0025 | 0.2737 | 0.0194 | 0.3606 | 0.1699 | 0.1380 | 0.2452 | 0.0745 | 0.2308 | 0.0467 | 0.1602 | 0.0182 | 0.0849 | 0.0044 | 0.0541 | 0.0000 | 0.0330 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0003 | 0.0003 | 0.0065 | 0.0072 | 0.0442 | 0.0379 | 0.0776 | 0.0649 | 0.0515 | 0.0468 | 0.0806 | 0.0673 | 0.7388 | 0.7756 | 0.0000 | 0.0001 | 0.0003 | 0.0006 | 0.0004 | 0.0007 | 0.0094 | 0.0113 | 0.0554 | 0.0601 | 0.1006 | 0.1144 | 0.0720 | 0.0756 | 0.1022 | 0.1029 | 0.6597 | 0.6343 | 0.0001 | 0.0000 | 0.0006 | 0.0064 | 0.0501 | 0.0888 | 0.0621 | 0.0936 | 0.6982 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 623 | 128 | | 5953 | 11599 | 530.3 | 117.08 | 264.39 | 415.53 | 392 | 428 | 458 | 485 | 513 | 546 | 584 | 630 | 696 | 0.0813 | 943 | 0.967 | 130.08 | 35.78 | 1 | 0.0519 | 309 | 0.0004 | 120.83 | 7.914 | 0.1104 | 294936.0 | 172000000 | 105000000000 | 66500000000000 | 0.4302 | 0.2128 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0059 | 0.0004 | 0.0185 | 0.0013 | 0.0765 | 0.0215 | 0.1506 | 0.0396 | 0.1458 | 0.0420 | 0.1956 | 0.0637 | 0.4064 | 0.8314 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0035 | 0.0000 | 0.0076 | 0.0003 | 0.0384 | 0.0137 | 0.0657 | 0.0215 | 0.0657 | 0.0178 | 0.0966 | 0.0280 | 0.7218 | 0.9187 | 0.0044 | 0.0061 | 0.0000 | 0.0214 | 0.0142 | 0.0428 | 0.0567 | 0.1284 | 0.1258 | 0.1743 | 0.1709 | 0.2110 | 0.1116 | 0.1376 | 0.1515 | 0.1407 | 0.3649 | 0.1376 | 0.0015 | 0.0015 | 0.0083 | 0.0326 | 0.0701 | 0.1227 | 0.0848 | 0.1148 | 0.5638 | 9 | 12 | 15 | 20 | 32 | 87 | 235 | 532 | 918 | 0.0999 | 84.61 | 5.018 | 0.5316 | 242548.0 | 294000000 | 414000000000 | 650000000000000 | 0.4380 | 0.2212 | 0.0713 | 0.0000 | 0.2240 | 0.0143 | 0.2261 | 0.1554 | 0.1344 | 0.1964 | 0.1303 | 0.1954 | 0.0876 | 0.1573 | 0.0448 | 0.0925 | 0.0407 | 0.0944 | 0.0407 | 0.0944 | 0.0006 | 0.0000 | 0.0003 | 0.0013 | 0.0014 | 0.0020 | 0.0089 | 0.0075 | 0.0371 | 0.0362 | 0.0674 | 0.0619 | 0.0438 | 0.0415 | 0.0726 | 0.0714 | 0.7680 | 0.7782 | 0.0006 | 0.0000 | 0.0000 | 0.0007 | 0.0013 | 0.0014 | 0.0055 | 0.0051 | 0.0375 | 0.0471 | 0.0789 | 0.0792 | 0.0465 | 0.0567 | 0.0818 | 0.0857 | 0.7478 | 0.7240 | 0.0003 | 0.0030 | 0.0021 | 0.0087 | 0.0382 | 0.0659 | 0.0454 | 0.0728 | 0.7636 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 577 | 529 | | 6874 | 21430 | 274.4 | 54.77 | 116.67 | 134.04 | 206 | 226 | 242 | 256 | 270 | 284 | 301 | 322 | 348 | 0.0497 | 1066 | 0.952 | 129.08 | 32.53 | 1 | 0.0428 | 294 | 0.0008 | 54.60 | 7.392 | 0.1620 | 78288.9 | 23200000 | 7120000000 | 2260000000000 | 0.4124 | 0.2339 | 0.0007 | 0.0000 | 0.0004 | 0.0000 | 0.0024 | 0.0002 | 0.0146 | 0.0009 | 0.0620 | 0.0167 | 0.1265 | 0.0357 | 0.1468 | 0.0339 | 0.1774 | 0.0560 | 0.4691 | 0.8567 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0052 | 0.0007 | 0.0245 | 0.0114 | 0.0505 | 0.0239 | 0.0545 | 0.0147 | 0.0759 | 0.0202 | 0.7879 | 0.9290 | 0.0068 | 0.0346 | 0.0101 | 0.0260 | 0.0245 | 0.1126 | 0.0785 | 0.1472 | 0.1647 | 0.2338 | 0.1976 | 0.1515 | 0.1309 | 0.1126 | 0.1512 | 0.1169 | 0.2356 | 0.0649 | 0.0012 | 0.0000 | 0.0080 | 0.0316 | 0.0807 | 0.1133 | 0.1072 | 0.1308 | 0.5272 | 10 | 13 | 16 | 28 | 55 | 99 | 154 | 222 | 315 | 0.0595 | 13.88 | 5.027 | 0.5286 | 31578.4 | 11600000 | 5190000000 | 2690000000000 | 0.5015 | 0.1536 | 0.0506 | 0.0016 | 0.2117 | 0.0180 | 0.3416 | 0.0886 | 0.1686 | 0.1769 | 0.1002 | 0.2501 | 0.0717 | 0.1846 | 0.0372 | 0.1200 | 0.0151 | 0.0904 | 0.0032 | 0.0698 | 0.0001 | 0.0000 | 0.0006 | 0.0005 | 0.0015 | 0.0008 | 0.0076 | 0.0083 | 0.0547 | 0.0435 | 0.0986 | 0.0770 | 0.0711 | 0.0601 | 0.1113 | 0.0927 | 0.6546 | 0.7171 | 0.0003 | 0.0007 | 0.0017 | 0.0016 | 0.0030 | 0.0034 | 0.0156 | 0.0219 | 0.0765 | 0.0905 | 0.1334 | 0.1420 | 0.0961 | 0.1062 | 0.1363 | 0.1430 | 0.5370 | 0.4906 | 0.0003 | 0.0010 | 0.0023 | 0.0117 | 0.0625 | 0.1168 | 0.0835 | 0.1295 | 0.5924 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 162 | 234 | | 7241 | 33553 | 311.8 | 96.47 | 118.63 | 162.69 | 187 | 201 | 237 | 287 | 318 | 345 | 372 | 400 | 436 | 0.0350 | 1175 | 0.651 | 97.19 | 15.30 | 2 | 0.0305 | 221 | 0.0011 | 37.81 | 7.274 | 0.2128 | 106500.0 | 39100000 | 15200000000 | 6200000000000 | 0.4774 | 0.1776 | 0.0004 | 0.0012 | 0.0025 | 0.0024 | 0.0078 | 0.0057 | 0.0252 | 0.0134 | 0.0900 | 0.0431 | 0.1460 | 0.0745 | 0.1488 | 0.0709 | 0.1729 | 0.1150 | 0.4064 | 0.6737 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0012 | 0.0045 | 0.0020 | 0.0085 | 0.0163 | 0.0263 | 0.0285 | 0.0387 | 0.0281 | 0.0343 | 0.0386 | 0.0461 | 0.8853 | 0.8385 | 0.0024 | 0.0155 | 0.0043 | 0.0127 | 0.0119 | 0.0325 | 0.0396 | 0.0876 | 0.0835 | 0.1441 | 0.1098 | 0.1935 | 0.1150 | 0.1483 | 0.1394 | 0.1384 | 0.4940 | 0.2274 | 0.0000 | 0.0011 | 0.0029 | 0.0135 | 0.0296 | 0.0630 | 0.0643 | 0.0849 | 0.7407 | 9 | 11 | 14 | 19 | 34 | 73 | 138 | 222 | 342 | 0.1019 | 11.63 | 4.467 | 0.5909 | 40541.7 | 20200000 | 12600000000 | 9300000000000 | 0.3536 | 0.3217 | 0.0195 | 0.0035 | 0.1006 | 0.0081 | 0.1840 | 0.0477 | 0.1733 | 0.1043 | 0.1800 | 0.1722 | 0.1418 | 0.1779 | 0.1082 | 0.1344 | 0.0594 | 0.1368 | 0.0332 | 0.2151 | 0.0001 | 0.0006 | 0.0006 | 0.0005 | 0.0020 | 0.0011 | 0.0085 | 0.0076 | 0.0341 | 0.0295 | 0.0563 | 0.0485 | 0.0428 | 0.0362 | 0.0619 | 0.0541 | 0.7937 | 0.8219 | 0.0001 | 0.0002 | 0.0013 | 0.0015 | 0.0028 | 0.0035 | 0.0110 | 0.0135 | 0.0448 | 0.0478 | 0.0745 | 0.0869 | 0.0567 | 0.0645 | 0.0842 | 0.0980 | 0.7246 | 0.6843 | 0.0002 | 0.0009 | 0.0028 | 0.0099 | 0.0385 | 0.0629 | 0.0519 | 0.0705 | 0.7623 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 810 | 326 | | 3594 | 12663 | 229.7 | 56.19 | 81.87 | 95.54 | 166 | 186 | 198 | 210 | 222 | 234 | 248 | 268 | 303 | 0.0682 | 864 | 1.030 | 171.21 | 41.76 | 1 | 0.1060 | 381 | 0.0016 | 32.05 | 6.715 | 0.2107 | 55902.4 | 14500000 | 4010000000 | 1190000000000 | 0.5035 | 0.1704 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0073 | 0.0012 | 0.0264 | 0.0054 | 0.0878 | 0.0239 | 0.1665 | 0.0760 | 0.1371 | 0.0611 | 0.1600 | 0.0899 | 0.4133 | 0.7424 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0006 | 0.0112 | 0.0031 | 0.0460 | 0.0184 | 0.0978 | 0.0535 | 0.0678 | 0.0337 | 0.0995 | 0.0538 | 0.6753 | 0.8370 | 0.0016 | 0.0131 | 0.0080 | 0.0218 | 0.0080 | 0.0306 | 0.0563 | 0.0961 | 0.1286 | 0.1747 | 0.1785 | 0.1790 | 0.1125 | 0.1004 | 0.1592 | 0.1048 | 0.3473 | 0.2795 | 0.0026 | 0.0045 | 0.0161 | 0.0407 | 0.0956 | 0.1305 | 0.0988 | 0.1292 | 0.4819 | 8 | 10 | 15 | 23 | 40 | 68 | 102 | 146 | 214 | 0.0700 | 5.97 | 4.296 | 0.5831 | 15830.0 | 4370000 | 1490000000 | 589000000000 | 0.5370 | 0.1417 | 0.0369 | 0.0017 | 0.1133 | 0.0166 | 0.1952 | 0.0706 | 0.1622 | 0.1025 | 0.1663 | 0.1515 | 0.1382 | 0.1893 | 0.0916 | 0.1295 | 0.0618 | 0.1295 | 0.0345 | 0.2088 | 0.0008 | 0.0002 | 0.0002 | 0.0007 | 0.0019 | 0.0021 | 0.0124 | 0.0091 | 0.0415 | 0.0341 | 0.0788 | 0.0600 | 0.0633 | 0.0464 | 0.0852 | 0.0678 | 0.7159 | 0.7797 | 0.0013 | 0.0006 | 0.0010 | 0.0015 | 0.0015 | 0.0067 | 0.0194 | 0.0236 | 0.0704 | 0.0744 | 0.1039 | 0.1254 | 0.0801 | 0.0828 | 0.1100 | 0.1108 | 0.6124 | 0.5742 | 0.0000 | 0.0013 | 0.0020 | 0.0132 | 0.0542 | 0.1022 | 0.0678 | 0.0910 | 0.6682 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 727 | 410 | | 4323 | 18730 | 284.9 | 68.71 | 48.75 | 82.54 | 205 | 226 | 243 | 259 | 275 | 295 | 317 | 340 | 377 | 0.0526 | 985 | 0.713 | 167.73 | 44.42 | 1 | 0.1020 | 441 | 0.0010 | 43.50 | 7.099 | 0.1678 | 85895.4 | 27400000 | 9230000000 | 3280000000000 | 0.4160 | 0.2277 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0066 | 0.0000 | 0.0210 | 0.0018 | 0.0798 | 0.0225 | 0.1736 | 0.0513 | 0.1569 | 0.0548 | 0.1853 | 0.0791 | 0.3760 | 0.7905 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0000 | 0.0082 | 0.0009 | 0.0360 | 0.0172 | 0.0703 | 0.0289 | 0.0670 | 0.0280 | 0.0861 | 0.0407 | 0.7289 | 0.8843 | 0.0059 | 0.0118 | 0.0071 | 0.0078 | 0.0142 | 0.0510 | 0.0673 | 0.0980 | 0.1311 | 0.1922 | 0.1865 | 0.1961 | 0.1074 | 0.1059 | 0.1287 | 0.1216 | 0.3518 | 0.2157 | 0.0021 | 0.0010 | 0.0088 | 0.0247 | 0.0809 | 0.1108 | 0.0876 | 0.1221 | 0.5621 | 6 | 8 | 9 | 11 | 13 | 18 | 32 | 65 | 143 | 0.1830 | 2.23 | 3.000 | 0.7083 | 9189.6 | 2810000 | 1040000000 | 430000000000 | 0.5119 | 0.1460 | 0.0261 | 0.0044 | 0.0782 | 0.0114 | 0.1583 | 0.0409 | 0.1676 | 0.0735 | 0.1918 | 0.1395 | 0.1629 | 0.1883 | 0.1006 | 0.1280 | 0.0726 | 0.1513 | 0.0419 | 0.2626 | 0.0010 | 0.0014 | 0.0014 | 0.0020 | 0.0028 | 0.0041 | 0.0130 | 0.0112 | 0.0434 | 0.0338 | 0.0578 | 0.0500 | 0.0580 | 0.0465 | 0.0811 | 0.0695 | 0.7414 | 0.7815 | 0.0000 | 0.0000 | 0.0018 | 0.0028 | 0.0040 | 0.0050 | 0.0143 | 0.0160 | 0.0564 | 0.0607 | 0.0804 | 0.0958 | 0.0666 | 0.0668 | 0.0927 | 0.0914 | 0.6839 | 0.6616 | 0.0000 | 0.0027 | 0.0049 | 0.0151 | 0.0457 | 0.0722 | 0.0624 | 0.0849 | 0.7122 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 193 | 840 | | 364 | 9991 | 79.4 | 12.33 | 120.69 | 125.11 | 64 | 69 | 71 | 74 | 78 | 82 | 86 | 91 | 97 | 0.0656 | 655 | 0.892 | 100.23 | 30.02 | 0 | 0.7033 | 256 | 0.0097 | 8.20 | 4.818 | 0.3329 | 6458.0 | 537560 | 45800000 | 3980000000 | 0.4026 | 0.2222 | 0.0000 | 0.0000 | 0.0248 | 0.0028 | 0.0106 | 0.0055 | 0.0496 | 0.0138 | 0.1028 | 0.0608 | 0.1950 | 0.1326 | 0.1915 | 0.0856 | 0.2340 | 0.1105 | 0.1915 | 0.5884 | 0.0000 | 0.0000 | 0.0210 | 0.0027 | 0.0060 | 0.0055 | 0.0330 | 0.0137 | 0.0571 | 0.0604 | 0.1171 | 0.1319 | 0.0781 | 0.0742 | 0.1171 | 0.0934 | 0.5706 | 0.6181 | 0.0196 | 0.0000 | 0.0980 | 1.0000 | 0.0392 | 0.0000 | 0.2549 | 0.0000 | 0.1765 | 0.0000 | 0.2157 | 0.0000 | 0.0980 | 0.0000 | 0.0980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0229 | 0.0571 | 0.0400 | 0.0971 | 0.1371 | 0.1371 | 0.1771 | 0.3314 | 24 | 37 | 47 | 57 | 70 | 90 | 126 | 190 | 293 | 0.0082 | 25.67 | 5.863 | 0.4219 | 30214.6 | 11500000 | 5470000000 | 2990000000000 | 0.6670 | 0.0790 | 0.0168 | 0.0063 | 0.0841 | 0.0145 | 0.1639 | 0.0396 | 0.1869 | 0.0903 | 0.1913 | 0.1538 | 0.1665 | 0.1778 | 0.0939 | 0.1436 | 0.0709 | 0.1429 | 0.0257 | 0.2312 | 0.0013 | 0.0029 | 0.0042 | 0.0050 | 0.0088 | 0.0091 | 0.0255 | 0.0213 | 0.0682 | 0.0615 | 0.1043 | 0.0886 | 0.0823 | 0.0797 | 0.1139 | 0.1042 | 0.5915 | 0.6276 | 0.0008 | 0.0009 | 0.0049 | 0.0070 | 0.0167 | 0.0127 | 0.0318 | 0.0417 | 0.0864 | 0.0961 | 0.1262 | 0.1298 | 0.0936 | 0.1039 | 0.1259 | 0.1373 | 0.5136 | 0.4706 | 0.0016 | 0.0055 | 0.0109 | 0.0257 | 0.0792 | 0.1136 | 0.0911 | 0.1171 | 0.5553 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1272 | 883 | | 1150 | 8995 | 239.8 | 65.75 | 123.62 | 67.46 | 158 | 173 | 191 | 209 | 232 | 258 | 286 | 306 | 330 | 0.0845 | 760 | 0.982 | 95.52 | 25.18 | 3 | 0.2000 | 230 | 0.0013 | 67.56 | 6.741 | 0.1434 | 61808.3 | 17000000 | 4910000000 | 1480000000000 | 0.4669 | 0.1629 | 0.0043 | 0.0010 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0469 | 0.0068 | 0.1919 | 0.0476 | 0.2751 | 0.1322 | 0.1663 | 0.0787 | 0.1215 | 0.1351 | 0.1919 | 0.5986 | 0.0013 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0150 | 0.0045 | 0.0614 | 0.0303 | 0.0852 | 0.1025 | 0.0576 | 0.0357 | 0.0827 | 0.0677 | 0.6967 | 0.7585 | 0.0000 | 0.0108 | 0.0000 | 0.0323 | 0.0000 | 0.0538 | 0.0274 | 0.1720 | 0.1337 | 0.1398 | 0.1125 | 0.1613 | 0.1155 | 0.1720 | 0.1763 | 0.1075 | 0.4347 | 0.1505 | 0.0000 | 0.0000 | 0.0019 | 0.0242 | 0.0576 | 0.1022 | 0.0762 | 0.0929 | 0.6450 | 49 | 64 | 78 | 92 | 110 | 130 | 153 | 178 | 216 | 0.0036 | 19.57 | 6.129 | 0.3167 | 19833.3 | 3880000 | 886000000 | 230000000000 | 0.5219 | 0.1301 | 0.0186 | 0.0026 | 0.0971 | 0.0077 | 0.1631 | 0.0208 | 0.1817 | 0.0612 | 0.1719 | 0.1229 | 0.1524 | 0.1718 | 0.1115 | 0.1593 | 0.0678 | 0.1860 | 0.0358 | 0.2677 | 0.0012 | 0.0012 | 0.0034 | 0.0023 | 0.0078 | 0.0055 | 0.0254 | 0.0158 | 0.0730 | 0.0453 | 0.1045 | 0.0772 | 0.1015 | 0.0721 | 0.1389 | 0.1101 | 0.5443 | 0.6705 | 0.0011 | 0.0082 | 0.0102 | 0.0169 | 0.0186 | 0.0416 | 0.0629 | 0.0914 | 0.1265 | 0.1422 | 0.1757 | 0.1792 | 0.1409 | 0.1555 | 0.1452 | 0.1247 | 0.3188 | 0.2402 | 0.0018 | 0.0043 | 0.0128 | 0.0337 | 0.0856 | 0.1573 | 0.1206 | 0.1418 | 0.4421 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 861 | 186 | | 12331 | 15671 | 289.1 | 82.48 | 116.02 | 160.19 | 201 | 225 | 243 | 260 | 276 | 292 | 314 | 345 | 400 | 0.0849 | 1331 | 0.663 | 177.34 | 56.46 | 4 | 0.0431 | 532 | 0.0008 | 58.20 | 7.495 | 0.1717 | 90380.5 | 30600000 | 11200000000 | 4470000000000 | 0.4343 | 0.2144 | 0.0007 | 0.0000 | 0.0013 | 0.0002 | 0.0081 | 0.0007 | 0.0252 | 0.0037 | 0.0800 | 0.0238 | 0.1386 | 0.0531 | 0.1412 | 0.0533 | 0.1670 | 0.0739 | 0.4380 | 0.7912 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0079 | 0.0009 | 0.0344 | 0.0131 | 0.0694 | 0.0240 | 0.0655 | 0.0205 | 0.0934 | 0.0333 | 0.7273 | 0.9081 | 0.0029 | 0.0034 | 0.0074 | 0.0068 | 0.0153 | 0.0316 | 0.0422 | 0.0769 | 0.1071 | 0.1435 | 0.1468 | 0.1973 | 0.1038 | 0.0991 | 0.1443 | 0.1307 | 0.4301 | 0.3108 | 0.0013 | 0.0040 | 0.0106 | 0.0361 | 0.0748 | 0.1272 | 0.0958 | 0.1105 | 0.5396 | 7 | 10 | 13 | 22 | 43 | 73 | 127 | 212 | 335 | 0.0704 | 13.83 | 4.641 | 0.5316 | 39120.6 | 20200000 | 14100000000 | 12400000000000 | 0.5640 | 0.1235 | 0.0406 | 0.0033 | 0.1589 | 0.0200 | 0.2525 | 0.0850 | 0.1954 | 0.1426 | 0.1432 | 0.1904 | 0.1043 | 0.1814 | 0.0579 | 0.1368 | 0.0281 | 0.1111 | 0.0190 | 0.1295 | 0.0000 | 0.0006 | 0.0009 | 0.0012 | 0.0034 | 0.0027 | 0.0101 | 0.0123 | 0.0575 | 0.0454 | 0.0885 | 0.0709 | 0.0600 | 0.0580 | 0.0942 | 0.0801 | 0.6855 | 0.7288 | 0.0002 | 0.0005 | 0.0009 | 0.0015 | 0.0041 | 0.0040 | 0.0175 | 0.0184 | 0.0723 | 0.0875 | 0.1159 | 0.1187 | 0.0771 | 0.0804 | 0.1104 | 0.1200 | 0.6016 | 0.5689 | 0.0000 | 0.0012 | 0.0028 | 0.0153 | 0.0630 | 0.1041 | 0.0675 | 0.1093 | 0.6367 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 610 | 740 | | 10995 | 21735 | 347.4 | 98.02 | 165.63 | 275.68 | 237 | 265 | 287 | 309 | 330 | 354 | 385 | 424 | 482 | 0.0543 | 1180 | 0.823 | 156.77 | 42.94 | 1 | 0.0379 | 417 | 0.0006 | 76.46 | 7.762 | 0.1421 | 130306.0 | 52800000 | 23000000000 | 10800000000000 | 0.4099 | 0.2391 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0050 | 0.0004 | 0.0293 | 0.0030 | 0.0976 | 0.0224 | 0.1934 | 0.0609 | 0.1532 | 0.0578 | 0.1697 | 0.0815 | 0.3511 | 0.7739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0001 | 0.0100 | 0.0014 | 0.0366 | 0.0128 | 0.0819 | 0.0266 | 0.0642 | 0.0246 | 0.0880 | 0.0371 | 0.7185 | 0.8974 | 0.0021 | 0.0038 | 0.0037 | 0.0104 | 0.0099 | 0.0133 | 0.0489 | 0.0579 | 0.1039 | 0.1670 | 0.1691 | 0.2201 | 0.1158 | 0.0911 | 0.1404 | 0.1670 | 0.4064 | 0.2695 | 0.0002 | 0.0032 | 0.0077 | 0.0270 | 0.0753 | 0.1302 | 0.0823 | 0.1115 | 0.5626 | 7 | 9 | 11 | 13 | 23 | 59 | 139 | 282 | 558 | 0.1212 | 27.49 | 4.518 | 0.5579 | 103430.0 | 90600000 | 93300000000 | 107000000000000 | 0.5655 | 0.1379 | 0.0639 | 0.0036 | 0.1916 | 0.0216 | 0.2652 | 0.1161 | 0.1568 | 0.1490 | 0.1285 | 0.1970 | 0.0930 | 0.1954 | 0.0558 | 0.1189 | 0.0323 | 0.1029 | 0.0129 | 0.0953 | 0.0002 | 0.0003 | 0.0003 | 0.0003 | 0.0008 | 0.0007 | 0.0092 | 0.0067 | 0.0505 | 0.0462 | 0.0921 | 0.0768 | 0.0586 | 0.0549 | 0.0894 | 0.0845 | 0.6990 | 0.7296 | 0.0004 | 0.0002 | 0.0007 | 0.0000 | 0.0020 | 0.0010 | 0.0127 | 0.0148 | 0.0665 | 0.0758 | 0.1061 | 0.1131 | 0.0700 | 0.0705 | 0.1023 | 0.1056 | 0.6393 | 0.6190 | 0.0003 | 0.0007 | 0.0012 | 0.0100 | 0.0608 | 0.1027 | 0.0621 | 0.0993 | 0.6629 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 146 | 51 | | 354 | 2232 | 83.5 | 10.81 | 232.77 | 142.92 | 70 | 73 | 77 | 80 | 83 | 86 | 89 | 94 | 99 | 0.1223 | 273 | 1.033 | 88.84 | 22.85 | 0 | 0.5791 | 205 | 0.0101 | 9.66 | 4.753 | 0.3349 | 7088.7 | 611712 | 53600000 | 4780000000 | 0.4194 | 0.1966 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0130 | 0.0028 | 0.0357 | 0.0085 | 0.0779 | 0.0397 | 0.1331 | 0.1473 | 0.1331 | 0.0368 | 0.2110 | 0.0822 | 0.3929 | 0.6827 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0030 | 0.0028 | 0.0178 | 0.0056 | 0.0562 | 0.0424 | 0.1124 | 0.1441 | 0.0621 | 0.0339 | 0.1213 | 0.0763 | 0.6243 | 0.6949 | 0.0000 | 1.0000 | 0.1000 | 0.0000 | 0.3667 | 0.0000 | 0.1000 | 0.0000 | 0.1667 | 0.0000 | 0.1333 | 0.0000 | 0.0667 | 0.0000 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0430 | 0.0699 | 0.1505 | 0.1720 | 0.1290 | 0.1559 | 0.2688 | 68 | 106 | 142 | 176 | 210 | 248 | 292 | 342 | 423 | 0.0013 | 85.74 | 6.901 | 0.1836 | 74597.8 | 29500000 | 13700000000 | 7190000000000 | 0.4379 | 0.1909 | 0.0169 | 0.0028 | 0.0639 | 0.0075 | 0.1899 | 0.0197 | 0.2199 | 0.0563 | 0.1748 | 0.1315 | 0.1485 | 0.1840 | 0.0846 | 0.1897 | 0.0639 | 0.1615 | 0.0376 | 0.2469 | 0.0008 | 0.0013 | 0.0016 | 0.0019 | 0.0055 | 0.0044 | 0.0181 | 0.0120 | 0.0604 | 0.0405 | 0.1319 | 0.0790 | 0.0981 | 0.0765 | 0.1389 | 0.0967 | 0.5447 | 0.6877 | 0.0013 | 0.0039 | 0.0054 | 0.0135 | 0.0148 | 0.0271 | 0.0620 | 0.0832 | 0.1334 | 0.1605 | 0.1536 | 0.1741 | 0.1361 | 0.1586 | 0.1860 | 0.1470 | 0.3073 | 0.2321 | 0.0000 | 0.0020 | 0.0121 | 0.0302 | 0.1099 | 0.1532 | 0.1149 | 0.1734 | 0.4042 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 767 | 375 | | 10994 | 36702 | 317.2 | 66.33 | 88.78 | 117.60 | 238 | 259 | 276 | 292 | 309 | 327 | 346 | 373 | 410 | 0.0385 | 1412 | 0.777 | 113.02 | 23.02 | 1 | 0.0226 | 249 | 0.0006 | 70.27 | 7.726 | 0.1479 | 104984.0 | 36300000 | 13000000000 | 4880000000000 | 0.4228 | 0.2250 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0001 | 0.0125 | 0.0008 | 0.0612 | 0.0134 | 0.1259 | 0.0305 | 0.1295 | 0.0324 | 0.1666 | 0.0567 | 0.4994 | 0.8660 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0062 | 0.0003 | 0.0265 | 0.0088 | 0.0510 | 0.0177 | 0.0541 | 0.0124 | 0.0766 | 0.0239 | 0.7828 | 0.9370 | 0.0031 | 0.0102 | 0.0078 | 0.0225 | 0.0225 | 0.0758 | 0.0628 | 0.1250 | 0.1313 | 0.1557 | 0.1763 | 0.1475 | 0.1104 | 0.1025 | 0.1423 | 0.1270 | 0.3433 | 0.2336 | 0.0010 | 0.0030 | 0.0062 | 0.0294 | 0.0726 | 0.1184 | 0.1031 | 0.1345 | 0.5318 | 10 | 12 | 14 | 19 | 32 | 55 | 97 | 156 | 255 | 0.0788 | 13.52 | 4.639 | 0.5538 | 21712.5 | 8010000 | 3800000000 | 2180000000000 | 0.4103 | 0.2154 | 0.0637 | 0.0009 | 0.2390 | 0.0098 | 0.3525 | 0.1068 | 0.1643 | 0.1924 | 0.0959 | 0.2534 | 0.0480 | 0.2004 | 0.0216 | 0.1040 | 0.0113 | 0.0742 | 0.0037 | 0.0580 | 0.0002 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0012 | 0.0109 | 0.0097 | 0.0639 | 0.0507 | 0.0964 | 0.0843 | 0.0715 | 0.0616 | 0.1087 | 0.0931 | 0.6473 | 0.6989 | 0.0002 | 0.0004 | 0.0011 | 0.0016 | 0.0034 | 0.0043 | 0.0175 | 0.0189 | 0.0814 | 0.0927 | 0.1222 | 0.1338 | 0.0853 | 0.0887 | 0.1273 | 0.1253 | 0.5616 | 0.5343 | 0.0001 | 0.0004 | 0.0016 | 0.0110 | 0.0724 | 0.1147 | 0.0774 | 0.1169 | 0.6055 |