High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1022 | 692 | | 3454 | 3530 | 167.4 | 41.65 | 180.50 | 117.23 | 122 | 134 | 143 | 152 | 160 | 170 | 182 | 197 | 221 | 0.1552 | 548 | 0.994 | 92.70 | 30.02 | 1 | 0.0753 | 260 | 0.0018 | 25.32 | 6.610 | 0.2337 | 29750.6 | 5640000 | 1140000000 | 247000000000 | 0.4167 | 0.2267 | 0.0019 | 0.0000 | 0.0014 | 0.0000 | 0.0079 | 0.0019 | 0.0200 | 0.0045 | 0.0723 | 0.0243 | 0.1361 | 0.0530 | 0.1441 | 0.0501 | 0.1716 | 0.0728 | 0.4448 | 0.7935 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0033 | 0.0000 | 0.0094 | 0.0012 | 0.0333 | 0.0171 | 0.0716 | 0.0339 | 0.0651 | 0.0233 | 0.0763 | 0.0369 | 0.7401 | 0.8876 | 0.0048 | 0.0078 | 0.0032 | 0.0078 | 0.0193 | 0.0273 | 0.0612 | 0.0898 | 0.1433 | 0.1406 | 0.1578 | 0.2031 | 0.1111 | 0.0898 | 0.1481 | 0.1680 | 0.3510 | 0.2656 | 0.0027 | 0.0040 | 0.0121 | 0.0336 | 0.0666 | 0.1217 | 0.0941 | 0.1163 | 0.5488 | 51 | 75 | 99 | 126 | 155 | 189 | 229 | 282 | 342 | 0.0019 | 49.51 | 6.719 | 0.2474 | 46319.3 | 14800000 | 5500000000 | 2270000000000 | 0.4820 | 0.1669 | 0.0110 | 0.0014 | 0.0992 | 0.0081 | 0.1983 | 0.0359 | 0.1832 | 0.0670 | 0.1749 | 0.1475 | 0.1405 | 0.2023 | 0.0992 | 0.1387 | 0.0702 | 0.1732 | 0.0234 | 0.2260 | 0.0011 | 0.0004 | 0.0032 | 0.0013 | 0.0053 | 0.0038 | 0.0185 | 0.0162 | 0.0678 | 0.0489 | 0.1070 | 0.0919 | 0.0970 | 0.0655 | 0.1436 | 0.1123 | 0.5564 | 0.6597 | 0.0017 | 0.0000 | 0.0078 | 0.0103 | 0.0138 | 0.0126 | 0.0491 | 0.0515 | 0.0956 | 0.1214 | 0.1731 | 0.1901 | 0.1051 | 0.1420 | 0.1447 | 0.1741 | 0.4091 | 0.2978 | 0.0013 | 0.0040 | 0.0047 | 0.0330 | 0.0982 | 0.1365 | 0.1063 | 0.1466 | 0.4694 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1013 | 776 | | 4132 | 4149 | 163.6 | 45.21 | 162.20 | 159.12 | 116 | 127 | 136 | 145 | 155 | 166 | 178 | 197 | 224 | 0.1347 | 559 | 1.127 | 94.07 | 29.83 | 1 | 0.0549 | 227 | 0.0016 | 35.59 | 6.765 | 0.2144 | 28795.0 | 5490000 | 1140000000 | 256000000000 | 0.3736 | 0.2711 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0097 | 0.0000 | 0.0313 | 0.0016 | 0.1031 | 0.0289 | 0.1793 | 0.0586 | 0.1696 | 0.0559 | 0.1608 | 0.0805 | 0.3449 | 0.7744 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0000 | 0.0126 | 0.0012 | 0.0426 | 0.0173 | 0.0765 | 0.0318 | 0.0726 | 0.0202 | 0.0833 | 0.0333 | 0.7089 | 0.8961 | 0.0012 | 0.0057 | 0.0060 | 0.0028 | 0.0193 | 0.0342 | 0.0712 | 0.1026 | 0.1351 | 0.1852 | 0.1689 | 0.1538 | 0.1074 | 0.1254 | 0.1544 | 0.1282 | 0.3366 | 0.2621 | 0.0006 | 0.0029 | 0.0081 | 0.0400 | 0.0737 | 0.1398 | 0.0986 | 0.1119 | 0.5244 | 19 | 39 | 59 | 79 | 105 | 140 | 187 | 267 | 405 | 0.0058 | 51.95 | 6.395 | 0.3274 | 51621.9 | 23000000 | 12200000000 | 7280000000000 | 0.4555 | 0.1933 | 0.0214 | 0.0008 | 0.1246 | 0.0084 | 0.2206 | 0.0489 | 0.1851 | 0.1281 | 0.1495 | 0.1778 | 0.1388 | 0.1912 | 0.0747 | 0.1272 | 0.0534 | 0.1348 | 0.0320 | 0.1828 | 0.0006 | 0.0000 | 0.0011 | 0.0036 | 0.0034 | 0.0027 | 0.0238 | 0.0173 | 0.0747 | 0.0600 | 0.1065 | 0.1055 | 0.0821 | 0.0673 | 0.1121 | 0.1014 | 0.5957 | 0.6421 | 0.0017 | 0.0000 | 0.0033 | 0.0040 | 0.0083 | 0.0049 | 0.0282 | 0.0346 | 0.0698 | 0.0949 | 0.1412 | 0.1215 | 0.0947 | 0.1057 | 0.1204 | 0.1364 | 0.5324 | 0.4980 | 0.0007 | 0.0034 | 0.0103 | 0.0248 | 0.0765 | 0.1254 | 0.0827 | 0.1158 | 0.5603 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1101 | 742 | | 4651 | 3841 | 130.8 | 24.62 | 205.76 | 139.04 | 103 | 111 | 116 | 122 | 128 | 133 | 140 | 148 | 161 | 0.1854 | 712 | 1.111 | 92.85 | 30.41 | 1 | 0.0495 | 230 | 0.0036 | 13.07 | 5.941 | 0.2993 | 17710.9 | 2490000 | 365000000 | 56000000000 | 0.4257 | 0.2249 | 0.0014 | 0.0000 | 0.0040 | 0.0000 | 0.0071 | 0.0000 | 0.0190 | 0.0025 | 0.0451 | 0.0167 | 0.0984 | 0.0362 | 0.1083 | 0.0292 | 0.1549 | 0.0442 | 0.5618 | 0.8712 | 0.0012 | 0.0000 | 0.0029 | 0.0000 | 0.0054 | 0.0000 | 0.0103 | 0.0017 | 0.0254 | 0.0129 | 0.0548 | 0.0241 | 0.0523 | 0.0146 | 0.0807 | 0.0226 | 0.7669 | 0.9241 | 0.0071 | 0.0059 | 0.0196 | 0.0294 | 0.0445 | 0.0471 | 0.0943 | 0.0824 | 0.1423 | 0.1765 | 0.1637 | 0.2176 | 0.1121 | 0.0706 | 0.1174 | 0.1647 | 0.2989 | 0.2059 | 0.0044 | 0.0083 | 0.0151 | 0.0432 | 0.0763 | 0.1122 | 0.1102 | 0.1336 | 0.4968 | 59 | 93 | 118 | 141 | 168 | 200 | 248 | 312 | 412 | 0.0015 | 56.43 | 6.903 | 0.2245 | 61663.9 | 23700000 | 10900000000 | 5660000000000 | 0.4849 | 0.1602 | 0.0169 | 0.0036 | 0.0784 | 0.0118 | 0.1858 | 0.0391 | 0.1701 | 0.0751 | 0.1725 | 0.1438 | 0.1556 | 0.1746 | 0.0941 | 0.1473 | 0.0760 | 0.1444 | 0.0507 | 0.2604 | 0.0020 | 0.0019 | 0.0040 | 0.0035 | 0.0106 | 0.0089 | 0.0323 | 0.0216 | 0.0751 | 0.0589 | 0.1280 | 0.0971 | 0.1154 | 0.0890 | 0.1260 | 0.1125 | 0.5066 | 0.6067 | 0.0017 | 0.0044 | 0.0121 | 0.0077 | 0.0113 | 0.0221 | 0.0459 | 0.0464 | 0.1013 | 0.1380 | 0.1636 | 0.1435 | 0.1022 | 0.1280 | 0.1411 | 0.1523 | 0.4208 | 0.3576 | 0.0020 | 0.0101 | 0.0181 | 0.0322 | 0.0938 | 0.1434 | 0.1139 | 0.1273 | 0.4591 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 819 | 741 | | 5979 | 6896 | 220.8 | 55.20 | 179.58 | 138.54 | 160 | 176 | 189 | 201 | 212 | 224 | 239 | 259 | 290 | 0.1115 | 769 | 1.055 | 105.12 | 32.02 | 1 | 0.0418 | 250 | 0.0010 | 54.65 | 7.224 | 0.1685 | 51796.9 | 13000000 | 3490000000 | 1010000000000 | 0.4435 | 0.2077 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0040 | 0.0000 | 0.0187 | 0.0015 | 0.0749 | 0.0195 | 0.1570 | 0.0462 | 0.1484 | 0.0436 | 0.1840 | 0.0676 | 0.4128 | 0.8214 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0000 | 0.0059 | 0.0002 | 0.0381 | 0.0134 | 0.0733 | 0.0232 | 0.0677 | 0.0209 | 0.1008 | 0.0375 | 0.7133 | 0.9047 | 0.0048 | 0.0024 | 0.0107 | 0.0000 | 0.0213 | 0.0095 | 0.0804 | 0.0735 | 0.1231 | 0.1659 | 0.1841 | 0.2109 | 0.0940 | 0.0948 | 0.1260 | 0.1469 | 0.3556 | 0.2962 | 0.0016 | 0.0020 | 0.0102 | 0.0317 | 0.0939 | 0.1412 | 0.1146 | 0.1451 | 0.4597 | 35 | 59 | 83 | 111 | 142 | 182 | 230 | 292 | 373 | 0.0020 | 58.17 | 6.937 | 0.2558 | 51437.9 | 19300000 | 8700000000 | 4480000000000 | 0.5354 | 0.1275 | 0.0234 | 0.0012 | 0.1292 | 0.0079 | 0.2559 | 0.0540 | 0.1882 | 0.1092 | 0.1683 | 0.1926 | 0.1110 | 0.1934 | 0.0642 | 0.1357 | 0.0399 | 0.1274 | 0.0199 | 0.1785 | 0.0000 | 0.0000 | 0.0012 | 0.0007 | 0.0041 | 0.0040 | 0.0199 | 0.0119 | 0.0809 | 0.0632 | 0.1232 | 0.1038 | 0.0870 | 0.0722 | 0.1300 | 0.1109 | 0.5537 | 0.6333 | 0.0022 | 0.0006 | 0.0018 | 0.0033 | 0.0106 | 0.0155 | 0.0343 | 0.0472 | 0.1004 | 0.1210 | 0.1612 | 0.1805 | 0.1233 | 0.1260 | 0.1440 | 0.1460 | 0.4223 | 0.3598 | 0.0018 | 0.0029 | 0.0068 | 0.0310 | 0.0863 | 0.1320 | 0.1059 | 0.1469 | 0.4864 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 666 | 790 | | 3561 | 6069 | 315.0 | 63.10 | 119.80 | 156.57 | 227 | 261 | 284 | 299 | 314 | 331 | 348 | 367 | 395 | 0.1005 | 610 | 0.944 | 100.02 | 29.00 | 1 | 0.0702 | 250 | 0.0018 | 20.47 | 6.604 | 0.2773 | 103228.0 | 35100000 | 12300000000 | 4460000000000 | 0.4022 | 0.2404 | 0.0004 | 0.0003 | 0.0000 | 0.0003 | 0.0021 | 0.0003 | 0.0141 | 0.0006 | 0.0428 | 0.0204 | 0.0782 | 0.0351 | 0.0669 | 0.0260 | 0.0973 | 0.0348 | 0.6981 | 0.8823 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0007 | 0.0003 | 0.0034 | 0.0003 | 0.0180 | 0.0162 | 0.0312 | 0.0272 | 0.0220 | 0.0139 | 0.0339 | 0.0210 | 0.8904 | 0.9206 | 0.0055 | 0.0000 | 0.0092 | 0.0000 | 0.0295 | 0.0000 | 0.0368 | 0.0000 | 0.0976 | 0.0000 | 0.1860 | 0.0000 | 0.0994 | 0.0000 | 0.1400 | 0.0000 | 0.3959 | 0.0000 | 0.0006 | 0.0011 | 0.0034 | 0.0169 | 0.0410 | 0.0713 | 0.0691 | 0.0871 | 0.7096 | 20 | 26 | 33 | 40 | 50 | 72 | 111 | 174 | 336 | 0.0366 | 13.58 | 4.709 | 0.5959 | 38861.2 | 20100000 | 13000000000 | 9720000000000 | 0.4035 | 0.2191 | 0.0130 | 0.0025 | 0.0681 | 0.0076 | 0.1426 | 0.0245 | 0.1313 | 0.0700 | 0.1361 | 0.1308 | 0.1669 | 0.1975 | 0.1070 | 0.1156 | 0.1216 | 0.1089 | 0.1135 | 0.3426 | 0.0000 | 0.0008 | 0.0005 | 0.0004 | 0.0044 | 0.0012 | 0.0112 | 0.0082 | 0.0486 | 0.0434 | 0.0816 | 0.0643 | 0.0505 | 0.0549 | 0.0802 | 0.0680 | 0.7230 | 0.7588 | 0.0007 | 0.0008 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0160 | 0.0159 | 0.0625 | 0.0700 | 0.1006 | 0.1026 | 0.0569 | 0.0644 | 0.0944 | 0.0907 | 0.6655 | 0.6547 | 0.0000 | 0.0035 | 0.0047 | 0.0135 | 0.0541 | 0.0858 | 0.0553 | 0.0829 | 0.7002 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 765 | 448 | | 1036 | 4704 | 600.2 | 210.48 | 6.20 | 1.84 | 332 | 391 | 444 | 509 | 577 | 659 | 743 | 818 | 904 | 0.0897 | 422 | 1.225 | 53.31 | 21.95 | 1 | 0.1332 | 138 | 0.0016 | 24.08 | 6.554 | 0.2404 | 404516.0 | 298000000 | 234000000000 | 192000000000000 | 0.3419 | 0.2894 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0031 | 0.0043 | 0.1242 | 0.0558 | 0.2329 | 0.1016 | 0.1304 | 0.0629 | 0.1739 | 0.0801 | 0.3354 | 0.6938 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0392 | 0.0339 | 0.0633 | 0.0532 | 0.0271 | 0.0271 | 0.0542 | 0.0407 | 0.8163 | 0.8439 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0324 | 0.0585 | 0.0649 | 0.0848 | 0.1135 | 0.0409 | 0.0757 | 0.0673 | 0.0811 | 0.7427 | 0.6324 | 0.0000 | 0.0000 | 0.0021 | 0.0062 | 0.0374 | 0.0811 | 0.0395 | 0.0457 | 0.7879 | 4 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 8 | 0.0274 | 6.20 | 3.980 | 0.3875 | 41.8 | 302.145 | 2320.55 | 18932.6 | 0.4537 | 0.1856 | 0.0023 | 0.0005 | 0.0113 | 0.0013 | 0.0441 | 0.0090 | 0.1027 | 0.0249 | 0.1782 | 0.0542 | 0.2398 | 0.1111 | 0.2262 | 0.2325 | 0.1613 | 0.3262 | 0.0341 | 0.2402 | 0.0000 | 0.0000 | 0.0017 | 0.0005 | 0.0047 | 0.0016 | 0.0231 | 0.0099 | 0.0540 | 0.0309 | 0.1005 | 0.0574 | 0.1816 | 0.1030 | 0.3028 | 0.2870 | 0.3314 | 0.5097 | 0.1740 | 0.3416 | 0.2290 | 0.2805 | 0.1980 | 0.1584 | 0.1530 | 0.1041 | 0.1140 | 0.0679 | 0.0770 | 0.0181 | 0.0260 | 0.0158 | 0.0230 | 0.0090 | 0.0060 | 0.0045 | 0.0029 | 0.0141 | 0.0417 | 0.0959 | 0.1617 | 0.2172 | 0.2159 | 0.1543 | 0.0962 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 508 | 386 | | 1856 | 6121 | 930.2 | 328.29 | 7.48 | 2.44 | 554 | 653 | 741 | 809 | 938 | 1045 | 1136 | 1227 | 1377 | 0.0853 | 522 | 1.026 | 43.86 | 14.14 | 1 | 0.0641 | 119 | 0.0008 | 115.28 | 7.271 | 0.1207 | 972996.0 | 1100000000 | 1310000000000 | 1.62E+15 | 0.4447 | 0.1728 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0173 | 0.0007 | 0.0317 | 0.0064 | 0.1400 | 0.0443 | 0.2107 | 0.1180 | 0.1486 | 0.0730 | 0.1962 | 0.1001 | 0.2554 | 0.6574 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0006 | 0.0093 | 0.0030 | 0.0388 | 0.0270 | 0.0705 | 0.0642 | 0.0496 | 0.0354 | 0.0659 | 0.0564 | 0.7651 | 0.8134 | 0.0034 | 0.0000 | 0.0000 | 0.0074 | 0.0000 | 0.0037 | 0.0201 | 0.0260 | 0.0586 | 0.1078 | 0.1273 | 0.1933 | 0.0771 | 0.0818 | 0.1039 | 0.0855 | 0.6097 | 0.4944 | 0.0000 | 0.0000 | 0.0000 | 0.0053 | 0.0427 | 0.0907 | 0.0491 | 0.0768 | 0.7353 | 5 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0178 | 7.81 | 4.411 | 0.3613 | 61.9 | 562.793 | 5603.58 | 60707.4 | 0.4721 | 0.1687 | 0.0133 | 0.0031 | 0.0511 | 0.0061 | 0.1011 | 0.0157 | 0.1867 | 0.0367 | 0.2357 | 0.0887 | 0.1933 | 0.1507 | 0.1532 | 0.2219 | 0.0544 | 0.2907 | 0.0113 | 0.1863 | 0.0006 | 0.0000 | 0.0046 | 0.0003 | 0.0191 | 0.0016 | 0.0469 | 0.0087 | 0.0879 | 0.0304 | 0.1387 | 0.0535 | 0.1808 | 0.0957 | 0.2333 | 0.2328 | 0.2882 | 0.5769 | 0.0957 | 0.1536 | 0.1428 | 0.1826 | 0.1400 | 0.1273 | 0.1328 | 0.0834 | 0.1079 | 0.0869 | 0.1063 | 0.0860 | 0.0847 | 0.0808 | 0.0841 | 0.0939 | 0.1057 | 0.1054 | 0.0056 | 0.0360 | 0.0685 | 0.1045 | 0.1391 | 0.1650 | 0.1550 | 0.1468 | 0.1796 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 781 | 933 | | 4650 | 7671 | 149.2 | 35.80 | 272.55 | 157.57 | 110 | 120 | 127 | 134 | 142 | 151 | 162 | 176 | 198 | 0.0948 | 727 | 1.075 | 97.75 | 27.80 | 1 | 0.0520 | 242 | 0.0020 | 26.81 | 6.558 | 0.2363 | 23531.1 | 3940000 | 699000000 | 132000000000 | 0.4493 | 0.1999 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0104 | 0.0002 | 0.0338 | 0.0009 | 0.0898 | 0.0243 | 0.1628 | 0.0471 | 0.1597 | 0.0468 | 0.1837 | 0.0695 | 0.3577 | 0.8111 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0002 | 0.0118 | 0.0004 | 0.0454 | 0.0150 | 0.0668 | 0.0232 | 0.0778 | 0.0163 | 0.1088 | 0.0306 | 0.6864 | 0.9142 | 0.0023 | 0.0030 | 0.0092 | 0.0060 | 0.0358 | 0.0329 | 0.0796 | 0.0928 | 0.1476 | 0.1707 | 0.1857 | 0.2335 | 0.1153 | 0.1138 | 0.1361 | 0.1707 | 0.2884 | 0.1766 | 0.0020 | 0.0035 | 0.0111 | 0.0308 | 0.0968 | 0.1402 | 0.1160 | 0.1452 | 0.4544 | 91 | 134 | 171 | 208 | 247 | 291 | 338 | 395 | 486 | 0.0007 | 96.75 | 7.538 | 0.1758 | 99105.9 | 44100000 | 22800000000 | 13300000000000 | 0.5485 | 0.1214 | 0.0151 | 0.0008 | 0.0764 | 0.0058 | 0.1871 | 0.0233 | 0.1861 | 0.0595 | 0.2027 | 0.1375 | 0.1554 | 0.2135 | 0.0941 | 0.1857 | 0.0520 | 0.1666 | 0.0312 | 0.2074 | 0.0009 | 0.0002 | 0.0030 | 0.0007 | 0.0077 | 0.0036 | 0.0219 | 0.0100 | 0.0743 | 0.0552 | 0.1272 | 0.1019 | 0.1078 | 0.0886 | 0.1429 | 0.1166 | 0.5144 | 0.6232 | 0.0008 | 0.0053 | 0.0106 | 0.0148 | 0.0203 | 0.0373 | 0.0519 | 0.0841 | 0.1339 | 0.1587 | 0.1729 | 0.1829 | 0.1303 | 0.1533 | 0.1652 | 0.1385 | 0.3141 | 0.2250 | 0.0009 | 0.0051 | 0.0146 | 0.0363 | 0.0991 | 0.1479 | 0.1303 | 0.1511 | 0.4148 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1030 | 874 | | 3673 | 4603 | 174.5 | 51.15 | 215.89 | 185.55 | 121 | 134 | 145 | 155 | 165 | 176 | 189 | 208 | 237 | 0.1288 | 593 | 1.114 | 100.81 | 36.62 | 1 | 0.0719 | 264 | 0.0014 | 45.62 | 6.851 | 0.2136 | 33048.1 | 6890000 | 1610000000 | 426000000000 | 0.4339 | 0.2118 | 0.0005 | 0.0000 | 0.0029 | 0.0003 | 0.0103 | 0.0009 | 0.0275 | 0.0024 | 0.1035 | 0.0323 | 0.1844 | 0.0579 | 0.1540 | 0.0695 | 0.1923 | 0.1040 | 0.3247 | 0.7325 | 0.0004 | 0.0000 | 0.0011 | 0.0003 | 0.0054 | 0.0006 | 0.0098 | 0.0011 | 0.0493 | 0.0198 | 0.0761 | 0.0320 | 0.0692 | 0.0315 | 0.1036 | 0.0546 | 0.6853 | 0.8602 | 0.0042 | 0.0032 | 0.0083 | 0.0288 | 0.0208 | 0.0192 | 0.0554 | 0.1058 | 0.1302 | 0.1827 | 0.1911 | 0.1538 | 0.0817 | 0.1250 | 0.1440 | 0.1410 | 0.3643 | 0.2404 | 0.0033 | 0.0026 | 0.0131 | 0.0328 | 0.0858 | 0.1343 | 0.0878 | 0.1304 | 0.5098 | 21 | 49 | 86 | 127 | 170 | 218 | 276 | 353 | 485 | 0.0039 | 128.55 | 7.024 | 0.2296 | 81028.4 | 39900000 | 23100000000 | 14900000000000 | 0.4728 | 0.1730 | 0.0382 | 0.0006 | 0.1401 | 0.0110 | 0.2051 | 0.0760 | 0.1949 | 0.1098 | 0.1809 | 0.1696 | 0.1121 | 0.1982 | 0.0650 | 0.1404 | 0.0420 | 0.1261 | 0.0217 | 0.1683 | 0.0009 | 0.0004 | 0.0026 | 0.0011 | 0.0035 | 0.0044 | 0.0215 | 0.0139 | 0.0953 | 0.0645 | 0.1156 | 0.1004 | 0.0888 | 0.0751 | 0.1301 | 0.1084 | 0.5417 | 0.6319 | 0.0013 | 0.0042 | 0.0080 | 0.0059 | 0.0195 | 0.0210 | 0.0436 | 0.0470 | 0.1113 | 0.1293 | 0.1482 | 0.1839 | 0.1261 | 0.1167 | 0.1368 | 0.1310 | 0.4051 | 0.3610 | 0.0021 | 0.0016 | 0.0102 | 0.0376 | 0.0950 | 0.1432 | 0.1073 | 0.1266 | 0.4764 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 292 | 776 | | 6777 | 12524 | 325.6 | 51.91 | 172.85 | 222.30 | 258 | 277 | 296 | 311 | 323 | 337 | 352 | 369 | 393 | 0.0787 | 986 | 1.019 | 135.34 | 41.01 | 1 | 0.0484 | 328 | 0.0017 | 16.93 | 6.629 | 0.2646 | 108700.0 | 37200000 | 13000000000 | 4670000000000 | 0.3905 | 0.2545 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0001 | 0.0131 | 0.0003 | 0.0300 | 0.0124 | 0.0571 | 0.0234 | 0.0742 | 0.0142 | 0.0991 | 0.0285 | 0.7210 | 0.9211 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0000 | 0.0071 | 0.0001 | 0.0167 | 0.0114 | 0.0295 | 0.0193 | 0.0326 | 0.0106 | 0.0443 | 0.0171 | 0.8660 | 0.9414 | 0.0057 | 0.0000 | 0.0114 | 0.0000 | 0.0341 | 0.0000 | 0.0994 | 0.0000 | 0.0994 | 0.0000 | 0.1605 | 0.0000 | 0.1179 | 0.0000 | 0.1264 | 0.0000 | 0.3452 | 0.0000 | 0.0015 | 0.0034 | 0.0073 | 0.0208 | 0.0531 | 0.0784 | 0.0815 | 0.1227 | 0.6313 | 14 | 16 | 19 | 25 | 51 | 113 | 215 | 343 | 515 | 0.0450 | 24.78 | 5.251 | 0.4914 | 79286.9 | 49200000 | 36500000000 | 31300000000000 | 0.4891 | 0.1521 | 0.0682 | 0.0006 | 0.2302 | 0.0144 | 0.3264 | 0.1428 | 0.1949 | 0.1888 | 0.1084 | 0.2199 | 0.0560 | 0.1929 | 0.0097 | 0.1180 | 0.0049 | 0.0760 | 0.0012 | 0.0466 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0015 | 0.0099 | 0.0101 | 0.0578 | 0.0482 | 0.0893 | 0.0778 | 0.0562 | 0.0523 | 0.0885 | 0.0782 | 0.6971 | 0.7317 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0023 | 0.0032 | 0.0138 | 0.0193 | 0.0706 | 0.0776 | 0.1115 | 0.1144 | 0.0701 | 0.0761 | 0.0996 | 0.1129 | 0.6310 | 0.5957 | 0.0000 | 0.0000 | 0.0012 | 0.0129 | 0.0628 | 0.1014 | 0.0584 | 0.0960 | 0.6673 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 599 | 374 | | 6551 | 17041 | 267.6 | 66.19 | 105.49 | 114.89 | 194 | 211 | 226 | 241 | 255 | 271 | 293 | 319 | 363 | 0.0596 | 1016 | 1.053 | 98.33 | 35.17 | 1 | 0.0400 | 262 | 0.0008 | 56.30 | 7.438 | 0.1617 | 75974.1 | 22900000 | 7350000000 | 2490000000000 | 0.4000 | 0.2484 | 0.0008 | 0.0000 | 0.0034 | 0.0003 | 0.0047 | 0.0005 | 0.0238 | 0.0032 | 0.0663 | 0.0219 | 0.1305 | 0.0441 | 0.1370 | 0.0413 | 0.1859 | 0.0657 | 0.4477 | 0.8230 | 0.0004 | 0.0000 | 0.0022 | 0.0000 | 0.0022 | 0.0000 | 0.0124 | 0.0008 | 0.0271 | 0.0139 | 0.0574 | 0.0225 | 0.0594 | 0.0169 | 0.0936 | 0.0300 | 0.7454 | 0.9159 | 0.0048 | 0.0079 | 0.0072 | 0.0099 | 0.0183 | 0.0217 | 0.0462 | 0.0791 | 0.0916 | 0.1462 | 0.1371 | 0.1798 | 0.1139 | 0.1146 | 0.1394 | 0.1462 | 0.4414 | 0.2945 | 0.0018 | 0.0029 | 0.0058 | 0.0282 | 0.0762 | 0.1181 | 0.0986 | 0.1203 | 0.5482 | 12 | 15 | 20 | 33 | 58 | 96 | 143 | 192 | 256 | 0.0374 | 9.37 | 5.007 | 0.5330 | 24326.7 | 7980000 | 3300000000 | 1610000000000 | 0.5431 | 0.1194 | 0.0353 | 0.0003 | 0.2286 | 0.0100 | 0.3382 | 0.1134 | 0.1429 | 0.1621 | 0.1127 | 0.2268 | 0.0793 | 0.2001 | 0.0390 | 0.1222 | 0.0157 | 0.0806 | 0.0082 | 0.0845 | 0.0001 | 0.0000 | 0.0003 | 0.0005 | 0.0014 | 0.0004 | 0.0096 | 0.0081 | 0.0557 | 0.0459 | 0.1000 | 0.0861 | 0.0671 | 0.0552 | 0.0956 | 0.0849 | 0.6703 | 0.7189 | 0.0002 | 0.0006 | 0.0016 | 0.0026 | 0.0019 | 0.0060 | 0.0157 | 0.0227 | 0.0714 | 0.0843 | 0.1314 | 0.1389 | 0.0812 | 0.0897 | 0.1127 | 0.1180 | 0.5839 | 0.5372 | 0.0002 | 0.0008 | 0.0031 | 0.0103 | 0.0642 | 0.1150 | 0.0771 | 0.1071 | 0.6223 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 866 | 124 | | 7868 | 18298 | 509.3 | 103.27 | 71.24 | 63.85 | 380 | 418 | 450 | 475 | 502 | 530 | 561 | 596 | 645 | 0.0624 | 1141 | 1.024 | 98.60 | 36.00 | 1 | 0.0336 | 264 | 0.0007 | 43.87 | 7.460 | 0.1703 | 270039.0 | 149000000 | 85000000000 | 50300000000000 | 0.4294 | 0.2140 | 0.0004 | 0.0000 | 0.0011 | 0.0001 | 0.0029 | 0.0005 | 0.0116 | 0.0009 | 0.0506 | 0.0141 | 0.0958 | 0.0303 | 0.1076 | 0.0255 | 0.1326 | 0.0412 | 0.5975 | 0.8874 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0044 | 0.0005 | 0.0218 | 0.0097 | 0.0421 | 0.0212 | 0.0456 | 0.0141 | 0.0611 | 0.0214 | 0.8231 | 0.9329 | 0.0015 | 0.0151 | 0.0115 | 0.0075 | 0.0137 | 0.0491 | 0.0634 | 0.0943 | 0.0977 | 0.1698 | 0.1504 | 0.1698 | 0.1107 | 0.1132 | 0.1427 | 0.1208 | 0.4084 | 0.2604 | 0.0005 | 0.0021 | 0.0061 | 0.0192 | 0.0541 | 0.0908 | 0.0842 | 0.1111 | 0.6320 | 12 | 20 | 32 | 44 | 56 | 67 | 82 | 103 | 155 | 0.0160 | 5.43 | 4.946 | 0.5259 | 9151.3 | 1720000 | 410000000 | 113000000000 | 0.3977 | 0.2161 | 0.0063 | 0.0014 | 0.0287 | 0.0034 | 0.0848 | 0.0127 | 0.1175 | 0.0402 | 0.1734 | 0.0962 | 0.1759 | 0.1181 | 0.1582 | 0.1348 | 0.1455 | 0.1664 | 0.1097 | 0.4269 | 0.0011 | 0.0006 | 0.0036 | 0.0013 | 0.0059 | 0.0046 | 0.0190 | 0.0127 | 0.0462 | 0.0332 | 0.0641 | 0.0471 | 0.0697 | 0.0516 | 0.0984 | 0.0760 | 0.6920 | 0.7730 | 0.0018 | 0.0028 | 0.0049 | 0.0062 | 0.0101 | 0.0130 | 0.0352 | 0.0370 | 0.0677 | 0.0795 | 0.0948 | 0.0956 | 0.0883 | 0.0857 | 0.1176 | 0.1134 | 0.5795 | 0.5667 | 0.0029 | 0.0063 | 0.0092 | 0.0245 | 0.0550 | 0.0789 | 0.0782 | 0.1114 | 0.6337 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1211 | 757 | | 6987 | 17413 | 330.1 | 42.49 | 131.75 | 174.14 | 277 | 295 | 309 | 320 | 331 | 341 | 352 | 366 | 384 | 0.0637 | 1110 | 0.875 | 72.84 | 16.16 | 1 | 0.0238 | 166 | 0.0022 | 16.55 | 6.447 | 0.2611 | 110777.0 | 37800000 | 13100000000 | 4580000000000 | 0.4400 | 0.2087 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0062 | 0.0000 | 0.0213 | 0.0109 | 0.0321 | 0.0178 | 0.0485 | 0.0100 | 0.0745 | 0.0186 | 0.8160 | 0.9427 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0000 | 0.0128 | 0.0109 | 0.0169 | 0.0178 | 0.0198 | 0.0095 | 0.0305 | 0.0166 | 0.9167 | 0.9453 | 0.0122 | 0.0000 | 0.0389 | 1.0000 | 0.0681 | 0.0000 | 0.1387 | 0.0000 | 0.1363 | 0.0000 | 0.1533 | 0.0000 | 0.1314 | 0.0000 | 0.1265 | 0.0000 | 0.1946 | 0.0000 | 0.0017 | 0.0047 | 0.0111 | 0.0255 | 0.0505 | 0.0813 | 0.0921 | 0.1160 | 0.6171 | 11 | 14 | 16 | 20 | 45 | 85 | 148 | 242 | 391 | 0.0761 | 18.56 | 4.883 | 0.5466 | 47679.7 | 24000000 | 14300000000 | 9510000000000 | 0.5710 | 0.1004 | 0.0354 | 0.0022 | 0.1286 | 0.0170 | 0.1973 | 0.0815 | 0.1517 | 0.1130 | 0.1402 | 0.1735 | 0.1156 | 0.1590 | 0.0860 | 0.1101 | 0.0744 | 0.1093 | 0.0708 | 0.2342 | 0.0002 | 0.0003 | 0.0005 | 0.0013 | 0.0017 | 0.0015 | 0.0103 | 0.0083 | 0.0444 | 0.0392 | 0.0713 | 0.0616 | 0.0547 | 0.0447 | 0.0799 | 0.0686 | 0.7370 | 0.7746 | 0.0002 | 0.0007 | 0.0022 | 0.0016 | 0.0044 | 0.0034 | 0.0156 | 0.0158 | 0.0577 | 0.0657 | 0.0944 | 0.1062 | 0.0716 | 0.0725 | 0.0954 | 0.1069 | 0.6586 | 0.6274 | 0.0004 | 0.0009 | 0.0034 | 0.0130 | 0.0497 | 0.0852 | 0.0639 | 0.0887 | 0.6949 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 937 | 869 | | 4358 | 4787 | 150.5 | 35.67 | 215.35 | 167.50 | 110 | 121 | 130 | 138 | 145 | 153 | 163 | 177 | 197 | 0.1249 | 598 | 1.001 | 107.62 | 26.02 | 1 | 0.0569 | 248 | 0.0019 | 28.98 | 6.582 | 0.2338 | 23927.0 | 4030000 | 718000000 | 136000000000 | 0.4618 | 0.1848 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0307 | 0.0025 | 0.0928 | 0.0234 | 0.1506 | 0.0557 | 0.1593 | 0.0605 | 0.1827 | 0.0891 | 0.3778 | 0.7688 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0113 | 0.0009 | 0.0423 | 0.0174 | 0.0675 | 0.0300 | 0.0805 | 0.0244 | 0.1032 | 0.0449 | 0.6920 | 0.8824 | 0.0053 | 0.0070 | 0.0119 | 0.0105 | 0.0185 | 0.0281 | 0.0793 | 0.1333 | 0.1506 | 0.2702 | 0.2127 | 0.1754 | 0.1136 | 0.1053 | 0.1532 | 0.1368 | 0.2550 | 0.1333 | 0.0032 | 0.0048 | 0.0117 | 0.0472 | 0.0881 | 0.1342 | 0.1146 | 0.1363 | 0.4599 | 40 | 68 | 99 | 133 | 170 | 220 | 274 | 347 | 446 | 0.0016 | 96.66 | 7.105 | 0.2131 | 74423.1 | 33600000 | 18100000000 | 10900000000000 | 0.5058 | 0.1647 | 0.0429 | 0.0024 | 0.1767 | 0.0102 | 0.2798 | 0.0783 | 0.1951 | 0.1428 | 0.1325 | 0.2055 | 0.0994 | 0.2127 | 0.0393 | 0.1350 | 0.0172 | 0.1183 | 0.0172 | 0.0950 | 0.0008 | 0.0007 | 0.0013 | 0.0020 | 0.0029 | 0.0038 | 0.0256 | 0.0133 | 0.0797 | 0.0673 | 0.1472 | 0.1206 | 0.1065 | 0.0823 | 0.1254 | 0.1209 | 0.5107 | 0.5891 | 0.0000 | 0.0016 | 0.0051 | 0.0048 | 0.0134 | 0.0104 | 0.0535 | 0.0670 | 0.1217 | 0.1316 | 0.1637 | 0.2041 | 0.1312 | 0.1276 | 0.1548 | 0.1515 | 0.3567 | 0.3014 | 0.0010 | 0.0035 | 0.0051 | 0.0238 | 0.1190 | 0.1570 | 0.1023 | 0.1489 | 0.4392 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 602 | 376 | | 1156 | 4064 | 474.2 | 143.37 | 10.35 | 8.30 | 315 | 334 | 360 | 391 | 431 | 490 | 562 | 644 | 697 | 0.0947 | 385 | 1.114 | 51.86 | 18.44 | 1 | 0.1211 | 140 | 0.0033 | 11.41 | 6.019 | 0.2906 | 245360.0 | 137000000 | 81700000000 | 51000000000000 | 0.3632 | 0.2648 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0025 | 0.0010 | 0.0327 | 0.0031 | 0.0955 | 0.0462 | 0.1382 | 0.0776 | 0.1709 | 0.0525 | 0.1608 | 0.0860 | 0.3995 | 0.7324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0009 | 0.0136 | 0.0017 | 0.0339 | 0.0304 | 0.0434 | 0.0470 | 0.0542 | 0.0261 | 0.0488 | 0.0487 | 0.8049 | 0.8452 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0118 | 0.0152 | 0.0559 | 0.0812 | 0.0588 | 0.0812 | 0.0559 | 0.0558 | 0.0765 | 0.1269 | 0.7412 | 0.6396 | 0.0000 | 0.0000 | 0.0000 | 0.0041 | 0.0412 | 0.0741 | 0.0329 | 0.0658 | 0.7819 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 15 | 0.0098 | 16.68 | 5.103 | 0.3379 | 176.1 | 6409.85 | 409709 | 33400000 | 0.4040 | 0.2136 | 0.0440 | 0.0038 | 0.1040 | 0.0105 | 0.1253 | 0.0332 | 0.2015 | 0.0514 | 0.2154 | 0.0867 | 0.1685 | 0.1160 | 0.1026 | 0.1499 | 0.0330 | 0.2376 | 0.0059 | 0.3110 | 0.0174 | 0.0014 | 0.0349 | 0.0052 | 0.0418 | 0.0193 | 0.0499 | 0.0293 | 0.0774 | 0.0503 | 0.1078 | 0.0748 | 0.1139 | 0.0871 | 0.1390 | 0.1550 | 0.4179 | 0.5775 | 0.0490 | 0.0472 | 0.0672 | 0.0407 | 0.0608 | 0.0650 | 0.0572 | 0.0911 | 0.0762 | 0.1382 | 0.1016 | 0.1154 | 0.1143 | 0.1073 | 0.1661 | 0.1268 | 0.3076 | 0.2683 | 0.0357 | 0.0421 | 0.0562 | 0.0761 | 0.0860 | 0.1094 | 0.1018 | 0.1281 | 0.3645 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 489 | 816 | | 9613 | 19666 | 390.1 | 60.27 | 175.40 | 251.54 | 316 | 341 | 358 | 372 | 386 | 400 | 417 | 439 | 471 | 0.0499 | 981 | 1.140 | 113.53 | 39.96 | 1 | 0.0287 | 276 | 0.0011 | 38.49 | 7.151 | 0.1882 | 155802.0 | 63700000 | 26600000000 | 11400000000000 | 0.4343 | 0.2166 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0063 | 0.0003 | 0.0283 | 0.0097 | 0.0643 | 0.0203 | 0.0756 | 0.0131 | 0.1055 | 0.0246 | 0.7186 | 0.9320 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0028 | 0.0001 | 0.0131 | 0.0084 | 0.0304 | 0.0170 | 0.0306 | 0.0084 | 0.0456 | 0.0152 | 0.8770 | 0.9508 | 0.0087 | 0.0000 | 0.0135 | 0.0000 | 0.0279 | 0.0000 | 0.0983 | 0.0000 | 0.1387 | 0.0000 | 0.1513 | 0.0000 | 0.1416 | 0.0000 | 0.1262 | 0.0000 | 0.2938 | 0.0000 | 0.0011 | 0.0035 | 0.0104 | 0.0298 | 0.0782 | 0.1108 | 0.1017 | 0.1210 | 0.5436 | 14 | 16 | 20 | 33 | 69 | 120 | 189 | 295 | 474 | 0.0394 | 31.15 | 5.368 | 0.5068 | 94034.5 | 84100000 | 103000000000 | 154000000000000 | 0.3897 | 0.2589 | 0.0213 | 0.0011 | 0.1385 | 0.0082 | 0.2420 | 0.0616 | 0.1776 | 0.1065 | 0.1672 | 0.1616 | 0.1236 | 0.1947 | 0.0759 | 0.1312 | 0.0374 | 0.1260 | 0.0167 | 0.2092 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0018 | 0.0009 | 0.0087 | 0.0075 | 0.0520 | 0.0374 | 0.0873 | 0.0660 | 0.0601 | 0.0490 | 0.0912 | 0.0703 | 0.6988 | 0.7683 | 0.0002 | 0.0002 | 0.0016 | 0.0006 | 0.0035 | 0.0034 | 0.0199 | 0.0226 | 0.0723 | 0.0866 | 0.1159 | 0.1289 | 0.0783 | 0.0860 | 0.1143 | 0.1210 | 0.5940 | 0.5507 | 0.0000 | 0.0008 | 0.0022 | 0.0144 | 0.0633 | 0.0998 | 0.0700 | 0.1025 | 0.6469 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1139 | 881 | | 6326 | 14317 | 189.9 | 47.31 | 165.02 | 129.26 | 138 | 151 | 161 | 171 | 182 | 193 | 206 | 224 | 252 | 0.0773 | 1106 | 1.024 | 100.80 | 38.29 | 1 | 0.0438 | 277 | 0.0012 | 42.09 | 7.012 | 0.1876 | 38280.7 | 8230000 | 1890000000 | 462000000000 | 0.4259 | 0.2291 | 0.0005 | 0.0000 | 0.0013 | 0.0000 | 0.0057 | 0.0000 | 0.0234 | 0.0019 | 0.0776 | 0.0210 | 0.1558 | 0.0447 | 0.1631 | 0.0445 | 0.1831 | 0.0635 | 0.3895 | 0.8244 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0000 | 0.0098 | 0.0003 | 0.0319 | 0.0121 | 0.0718 | 0.0241 | 0.0706 | 0.0168 | 0.0970 | 0.0254 | 0.7152 | 0.9213 | 0.0052 | 0.0064 | 0.0103 | 0.0107 | 0.0207 | 0.0258 | 0.0767 | 0.0794 | 0.1259 | 0.1803 | 0.1759 | 0.1674 | 0.1190 | 0.1180 | 0.1250 | 0.1545 | 0.3414 | 0.2575 | 0.0007 | 0.0055 | 0.0117 | 0.0371 | 0.0950 | 0.1273 | 0.1185 | 0.1383 | 0.4659 | 34 | 48 | 69 | 97 | 132 | 170 | 214 | 268 | 354 | 0.0028 | 59.79 | 6.896 | 0.2662 | 43937.1 | 15200000 | 6170000000 | 2820000000000 | 0.5199 | 0.1445 | 0.0243 | 0.0025 | 0.1004 | 0.0068 | 0.2160 | 0.0533 | 0.1831 | 0.1121 | 0.1711 | 0.1528 | 0.1263 | 0.1873 | 0.0814 | 0.1483 | 0.0675 | 0.1416 | 0.0300 | 0.1953 | 0.0008 | 0.0007 | 0.0008 | 0.0002 | 0.0040 | 0.0028 | 0.0205 | 0.0158 | 0.0656 | 0.0457 | 0.0960 | 0.0802 | 0.0795 | 0.0679 | 0.1224 | 0.0924 | 0.6103 | 0.6942 | 0.0013 | 0.0018 | 0.0055 | 0.0060 | 0.0103 | 0.0189 | 0.0352 | 0.0463 | 0.0967 | 0.1178 | 0.1415 | 0.1568 | 0.1118 | 0.1307 | 0.1417 | 0.1494 | 0.4561 | 0.3722 | 0.0007 | 0.0012 | 0.0066 | 0.0298 | 0.0752 | 0.1185 | 0.1015 | 0.1342 | 0.5323 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1189 | 155 | | 5618 | 13253 | 344.2 | 70.32 | 104.68 | 99.98 | 259 | 282 | 300 | 316 | 333 | 354 | 379 | 407 | 444 | 0.0684 | 907 | 0.910 | 83.20 | 23.02 | 1 | 0.0377 | 212 | 0.0019 | 20.54 | 6.561 | 0.2353 | 123384.0 | 46000000 | 17900000000 | 7180000000000 | 0.3957 | 0.2470 | 0.0003 | 0.0000 | 0.0008 | 0.0002 | 0.0063 | 0.0002 | 0.0181 | 0.0011 | 0.0550 | 0.0161 | 0.1125 | 0.0345 | 0.1341 | 0.0319 | 0.1675 | 0.0521 | 0.5055 | 0.8638 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0032 | 0.0000 | 0.0071 | 0.0002 | 0.0199 | 0.0120 | 0.0402 | 0.0218 | 0.0557 | 0.0130 | 0.0771 | 0.0230 | 0.7960 | 0.9301 | 0.0029 | 0.0140 | 0.0069 | 0.0421 | 0.0255 | 0.0514 | 0.0609 | 0.1495 | 0.1159 | 0.1822 | 0.1906 | 0.1869 | 0.1375 | 0.1122 | 0.1503 | 0.1075 | 0.3094 | 0.1542 | 0.0020 | 0.0024 | 0.0071 | 0.0256 | 0.0643 | 0.1057 | 0.0923 | 0.1179 | 0.5826 | 14 | 27 | 43 | 59 | 75 | 94 | 119 | 159 | 237 | 0.0186 | 8.63 | 5.042 | 0.5074 | 20954.6 | 6170000 | 2290000000 | 982000000000 | 0.4377 | 0.2064 | 0.0105 | 0.0017 | 0.0659 | 0.0063 | 0.1467 | 0.0244 | 0.1714 | 0.0701 | 0.1841 | 0.1287 | 0.1586 | 0.1670 | 0.1270 | 0.1575 | 0.0857 | 0.1608 | 0.0501 | 0.2834 | 0.0010 | 0.0010 | 0.0042 | 0.0013 | 0.0055 | 0.0034 | 0.0205 | 0.0174 | 0.0627 | 0.0477 | 0.0920 | 0.0753 | 0.0818 | 0.0727 | 0.1040 | 0.0953 | 0.6284 | 0.6859 | 0.0011 | 0.0027 | 0.0038 | 0.0036 | 0.0089 | 0.0103 | 0.0277 | 0.0262 | 0.0728 | 0.0839 | 0.1098 | 0.1194 | 0.0899 | 0.0902 | 0.1106 | 0.1154 | 0.5756 | 0.5484 | 0.0011 | 0.0045 | 0.0087 | 0.0268 | 0.0665 | 0.1035 | 0.0854 | 0.1079 | 0.5957 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 373 | 297 | | 8100 | 26881 | 413.8 | 80.21 | 134.66 | 112.18 | 311 | 343 | 368 | 389 | 410 | 432 | 457 | 483 | 520 | 0.0428 | 1150 | 1.063 | 121.84 | 35.38 | 1 | 0.0363 | 294 | 0.0012 | 29.87 | 6.930 | 0.2112 | 177657.0 | 78900000 | 36200000000 | 17100000000000 | 0.4441 | 0.2061 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0031 | 0.0001 | 0.0127 | 0.0006 | 0.0529 | 0.0119 | 0.1206 | 0.0278 | 0.1395 | 0.0227 | 0.1558 | 0.0414 | 0.5151 | 0.8954 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0038 | 0.0005 | 0.0215 | 0.0096 | 0.0486 | 0.0211 | 0.0558 | 0.0122 | 0.0700 | 0.0216 | 0.7987 | 0.9350 | 0.0038 | 0.0471 | 0.0045 | 0.0059 | 0.0257 | 0.0941 | 0.0863 | 0.1588 | 0.1529 | 0.1412 | 0.2044 | 0.2118 | 0.1317 | 0.0647 | 0.1363 | 0.0706 | 0.2544 | 0.2059 | 0.0005 | 0.0013 | 0.0066 | 0.0247 | 0.0683 | 0.1268 | 0.1056 | 0.1298 | 0.5363 | 27 | 46 | 66 | 85 | 107 | 130 | 159 | 200 | 272 | 0.0091 | 10.68 | 5.490 | 0.4380 | 30717.4 | 10300000 | 4530000000 | 2410000000000 | 0.4651 | 0.1879 | 0.0107 | 0.0010 | 0.0569 | 0.0033 | 0.1502 | 0.0207 | 0.1620 | 0.0586 | 0.1808 | 0.1345 | 0.1705 | 0.1748 | 0.1171 | 0.1516 | 0.0871 | 0.1645 | 0.0646 | 0.2909 | 0.0008 | 0.0005 | 0.0020 | 0.0009 | 0.0061 | 0.0038 | 0.0179 | 0.0117 | 0.0589 | 0.0446 | 0.1034 | 0.0774 | 0.0837 | 0.0680 | 0.1176 | 0.1006 | 0.6097 | 0.6925 | 0.0016 | 0.0022 | 0.0055 | 0.0050 | 0.0095 | 0.0162 | 0.0356 | 0.0429 | 0.0832 | 0.1003 | 0.1356 | 0.1457 | 0.1111 | 0.1195 | 0.1349 | 0.1425 | 0.4830 | 0.4257 | 0.0007 | 0.0045 | 0.0076 | 0.0250 | 0.0755 | 0.1170 | 0.0983 | 0.1280 | 0.5435 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 560 | 270 | | 5568 | 18268 | 433.5 | 92.93 | 137.20 | 136.94 | 324 | 352 | 376 | 397 | 422 | 446 | 477 | 510 | 564 | 0.0541 | 989 | 1.182 | 95.60 | 36.50 | 1 | 0.0449 | 250 | 0.0012 | 33.93 | 7.010 | 0.1946 | 196527.0 | 93100000 | 46100000000 | 23700000000000 | 0.4332 | 0.2136 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0020 | 0.0002 | 0.0140 | 0.0011 | 0.0717 | 0.0192 | 0.1259 | 0.0400 | 0.1320 | 0.0390 | 0.1664 | 0.0581 | 0.4877 | 0.8422 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0064 | 0.0000 | 0.0304 | 0.0128 | 0.0556 | 0.0229 | 0.0530 | 0.0152 | 0.0754 | 0.0265 | 0.7781 | 0.9225 | 0.0031 | 0.0070 | 0.0071 | 0.0245 | 0.0224 | 0.0280 | 0.0671 | 0.1294 | 0.1180 | 0.1993 | 0.1699 | 0.2133 | 0.1282 | 0.1084 | 0.1506 | 0.1434 | 0.3337 | 0.1469 | 0.0020 | 0.0016 | 0.0052 | 0.0290 | 0.0708 | 0.1225 | 0.0982 | 0.1301 | 0.5406 | 20 | 35 | 55 | 76 | 97 | 124 | 159 | 209 | 290 | 0.0125 | 11.31 | 5.396 | 0.4946 | 37572.9 | 16400000 | 9620000000 | 6730000000000 | 0.5560 | 0.1152 | 0.0139 | 0.0011 | 0.0448 | 0.0071 | 0.1227 | 0.0245 | 0.1370 | 0.0568 | 0.1652 | 0.1234 | 0.1675 | 0.1608 | 0.1217 | 0.1315 | 0.1118 | 0.1516 | 0.1154 | 0.3433 | 0.0013 | 0.0001 | 0.0016 | 0.0026 | 0.0052 | 0.0039 | 0.0169 | 0.0131 | 0.0498 | 0.0475 | 0.0829 | 0.0732 | 0.0663 | 0.0599 | 0.0861 | 0.0802 | 0.6900 | 0.7194 | 0.0015 | 0.0007 | 0.0029 | 0.0034 | 0.0061 | 0.0079 | 0.0209 | 0.0274 | 0.0672 | 0.0758 | 0.1087 | 0.1185 | 0.0846 | 0.0902 | 0.1045 | 0.1152 | 0.6036 | 0.5609 | 0.0021 | 0.0021 | 0.0044 | 0.0190 | 0.0539 | 0.0970 | 0.0768 | 0.0992 | 0.6453 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 177 | 313 | | 5638 | 13933 | 398.6 | 102.35 | 102.66 | 164.28 | 278 | 312 | 338 | 363 | 391 | 418 | 444 | 477 | 530 | 0.0646 | 900 | 1.105 | 128.16 | 40.36 | 1 | 0.0566 | 319 | 0.0011 | 32.90 | 7.036 | 0.2099 | 169382.0 | 76400000 | 36500000000 | 18500000000000 | 0.3917 | 0.2443 | 0.0000 | 0.0002 | 0.0018 | 0.0000 | 0.0052 | 0.0006 | 0.0231 | 0.0041 | 0.0686 | 0.0246 | 0.1196 | 0.0553 | 0.1310 | 0.0452 | 0.1734 | 0.0712 | 0.4774 | 0.7988 | 0.0000 | 0.0002 | 0.0007 | 0.0000 | 0.0025 | 0.0004 | 0.0080 | 0.0026 | 0.0243 | 0.0159 | 0.0491 | 0.0316 | 0.0505 | 0.0232 | 0.0757 | 0.0338 | 0.7892 | 0.8923 | 0.0054 | 0.0078 | 0.0045 | 0.0207 | 0.0118 | 0.0181 | 0.0570 | 0.0622 | 0.1230 | 0.1425 | 0.1203 | 0.2409 | 0.1401 | 0.1295 | 0.1528 | 0.1529 | 0.3852 | 0.2254 | 0.0011 | 0.0011 | 0.0023 | 0.0196 | 0.0495 | 0.1072 | 0.0966 | 0.1076 | 0.6149 | 10 | 13 | 19 | 31 | 50 | 75 | 104 | 145 | 221 | 0.0586 | 9.85 | 4.528 | 0.5850 | 37525.9 | 28000000 | 28100000000 | 32100000000000 | 0.6066 | 0.1047 | 0.0130 | 0.0014 | 0.0691 | 0.0060 | 0.1943 | 0.0246 | 0.2038 | 0.0773 | 0.1991 | 0.1586 | 0.1471 | 0.2025 | 0.0939 | 0.1627 | 0.0585 | 0.1518 | 0.0213 | 0.2151 | 0.0004 | 0.0002 | 0.0023 | 0.0006 | 0.0041 | 0.0022 | 0.0209 | 0.0180 | 0.0638 | 0.0512 | 0.0976 | 0.0888 | 0.0749 | 0.0667 | 0.1049 | 0.0915 | 0.6311 | 0.6808 | 0.0012 | 0.0036 | 0.0023 | 0.0047 | 0.0092 | 0.0118 | 0.0286 | 0.0383 | 0.0754 | 0.0777 | 0.1265 | 0.1310 | 0.0826 | 0.0917 | 0.1129 | 0.1167 | 0.5614 | 0.5245 | 0.0014 | 0.0033 | 0.0064 | 0.0226 | 0.0683 | 0.1045 | 0.0824 | 0.1106 | 0.6005 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 845 | 391 | | 8714 | 28501 | 282.2 | 64.28 | 121.16 | 121.03 | 206 | 227 | 243 | 259 | 276 | 293 | 313 | 334 | 368 | 0.0454 | 1293 | 1.148 | 102.08 | 30.46 | 1 | 0.0270 | 235 | 0.0023 | 14.79 | 6.394 | 0.2854 | 83742.3 | 26100000 | 8530000000 | 2910000000000 | 0.4516 | 0.1999 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0048 | 0.0004 | 0.0140 | 0.0014 | 0.0658 | 0.0182 | 0.1361 | 0.0403 | 0.1469 | 0.0472 | 0.1796 | 0.0612 | 0.4515 | 0.8313 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0002 | 0.0057 | 0.0007 | 0.0319 | 0.0118 | 0.0595 | 0.0218 | 0.0612 | 0.0237 | 0.0824 | 0.0326 | 0.7570 | 0.9091 | 0.0044 | 0.0000 | 0.0062 | 0.0143 | 0.0187 | 0.0531 | 0.0704 | 0.0755 | 0.1172 | 0.1633 | 0.1509 | 0.2286 | 0.1010 | 0.0857 | 0.1415 | 0.1429 | 0.3897 | 0.2367 | 0.0005 | 0.0007 | 0.0074 | 0.0253 | 0.0763 | 0.1144 | 0.0817 | 0.1207 | 0.5730 | 16 | 28 | 45 | 64 | 86 | 111 | 142 | 189 | 270 | 0.0173 | 10.15 | 5.255 | 0.4896 | 29326.3 | 11100000 | 5770000000 | 3740000000000 | 0.5092 | 0.1670 | 0.0151 | 0.0015 | 0.0740 | 0.0061 | 0.1650 | 0.0287 | 0.1715 | 0.0720 | 0.1760 | 0.1555 | 0.1560 | 0.1872 | 0.1115 | 0.1505 | 0.0848 | 0.1481 | 0.0462 | 0.2505 | 0.0002 | 0.0005 | 0.0014 | 0.0011 | 0.0052 | 0.0033 | 0.0204 | 0.0126 | 0.0607 | 0.0488 | 0.0975 | 0.0843 | 0.0811 | 0.0687 | 0.1062 | 0.0968 | 0.6273 | 0.6839 | 0.0018 | 0.0015 | 0.0029 | 0.0027 | 0.0062 | 0.0087 | 0.0255 | 0.0332 | 0.0815 | 0.0912 | 0.1277 | 0.1335 | 0.0916 | 0.0982 | 0.1235 | 0.1301 | 0.5393 | 0.5010 | 0.0013 | 0.0021 | 0.0052 | 0.0239 | 0.0719 | 0.1113 | 0.0898 | 0.1163 | 0.5781 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 504 | 454 | | 4632 | 9949 | 526.7 | 103.94 | 144.23 | 161.03 | 403 | 434 | 461 | 488 | 517 | 541 | 573 | 613 | 674 | 0.0767 | 763 | 1.167 | 101.13 | 34.54 | 1 | 0.0531 | 246 | 0.0009 | 55.30 | 7.231 | 0.1624 | 288245.0 | 164000000 | 96700000000 | 59100000000000 | 0.4365 | 0.2052 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0095 | 0.0004 | 0.0653 | 0.0181 | 0.1242 | 0.0349 | 0.1378 | 0.0329 | 0.1714 | 0.0511 | 0.4897 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0044 | 0.0002 | 0.0279 | 0.0136 | 0.0541 | 0.0242 | 0.0597 | 0.0141 | 0.0859 | 0.0249 | 0.7668 | 0.9230 | 0.0054 | 0.0188 | 0.0054 | 0.0125 | 0.0201 | 0.0313 | 0.0698 | 0.1438 | 0.1557 | 0.2438 | 0.1906 | 0.1750 | 0.1302 | 0.1188 | 0.1664 | 0.1563 | 0.2564 | 0.1000 | 0.0009 | 0.0038 | 0.0033 | 0.0302 | 0.0797 | 0.1282 | 0.1249 | 0.1556 | 0.4734 | 18 | 28 | 46 | 67 | 93 | 124 | 163 | 220 | 330 | 0.0156 | 19.65 | 5.459 | 0.4608 | 46729.0 | 24700000 | 17300000000 | 14400000000000 | 0.5530 | 0.1302 | 0.0176 | 0.0010 | 0.1067 | 0.0100 | 0.2360 | 0.0424 | 0.1854 | 0.0883 | 0.1601 | 0.1621 | 0.1292 | 0.2014 | 0.0730 | 0.1717 | 0.0597 | 0.1438 | 0.0323 | 0.1793 | 0.0002 | 0.0000 | 0.0009 | 0.0012 | 0.0024 | 0.0019 | 0.0176 | 0.0129 | 0.0691 | 0.0574 | 0.1203 | 0.0945 | 0.0888 | 0.0781 | 0.1108 | 0.1107 | 0.5899 | 0.6432 | 0.0004 | 0.0009 | 0.0011 | 0.0022 | 0.0061 | 0.0106 | 0.0301 | 0.0396 | 0.1050 | 0.1091 | 0.1384 | 0.1552 | 0.0986 | 0.0994 | 0.1376 | 0.1271 | 0.4828 | 0.4560 | 0.0017 | 0.0012 | 0.0043 | 0.0240 | 0.0822 | 0.1343 | 0.0909 | 0.1308 | 0.5305 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 634 | 828 | | 6200 | 7303 | 203.7 | 43.18 | 209.83 | 149.65 | 154 | 167 | 178 | 188 | 198 | 208 | 221 | 237 | 262 | 0.1191 | 870 | 1.113 | 92.59 | 26.68 | 1 | 0.0353 | 219 | 0.0012 | 41.78 | 7.014 | 0.1838 | 43340.5 | 9650000 | 2250000000 | 547000000000 | 0.4334 | 0.2122 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0031 | 0.0003 | 0.0157 | 0.0007 | 0.0711 | 0.0174 | 0.1256 | 0.0376 | 0.1517 | 0.0398 | 0.1830 | 0.0615 | 0.4490 | 0.8428 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0002 | 0.0066 | 0.0000 | 0.0335 | 0.0122 | 0.0534 | 0.0229 | 0.0720 | 0.0143 | 0.0964 | 0.0265 | 0.7359 | 0.9239 | 0.0059 | 0.0102 | 0.0088 | 0.0307 | 0.0137 | 0.0648 | 0.0715 | 0.1160 | 0.1538 | 0.1945 | 0.1851 | 0.1672 | 0.1303 | 0.1297 | 0.1538 | 0.1229 | 0.2772 | 0.1638 | 0.0025 | 0.0040 | 0.0087 | 0.0395 | 0.0938 | 0.1242 | 0.1177 | 0.1409 | 0.4687 | 40 | 70 | 103 | 137 | 177 | 225 | 280 | 343 | 426 | 0.0014 | 93.66 | 7.304 | 0.1920 | 66420.4 | 25900000 | 11500000000 | 5580000000000 | 0.5796 | 0.1202 | 0.0390 | 0.0023 | 0.1851 | 0.0148 | 0.2695 | 0.0760 | 0.1802 | 0.1442 | 0.1420 | 0.1832 | 0.1063 | 0.2186 | 0.0446 | 0.1454 | 0.0219 | 0.1134 | 0.0114 | 0.1021 | 0.0005 | 0.0007 | 0.0029 | 0.0009 | 0.0084 | 0.0050 | 0.0260 | 0.0176 | 0.0825 | 0.0686 | 0.1372 | 0.1114 | 0.1075 | 0.0997 | 0.1319 | 0.1233 | 0.5030 | 0.5729 | 0.0019 | 0.0034 | 0.0051 | 0.0059 | 0.0179 | 0.0206 | 0.0451 | 0.0677 | 0.1147 | 0.1290 | 0.1683 | 0.1986 | 0.1306 | 0.1226 | 0.1446 | 0.1466 | 0.3719 | 0.3055 | 0.0003 | 0.0064 | 0.0121 | 0.0359 | 0.0978 | 0.1547 | 0.1134 | 0.1556 | 0.4239 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 317 | 690 | | 3464 | 11834 | 342.0 | 75.63 | 178.33 | 204.51 | 250 | 275 | 296 | 316 | 334 | 353 | 374 | 407 | 449 | 0.0724 | 857 | 0.954 | 122.41 | 43.14 | 1 | 0.0944 | 327 | 0.0010 | 39.91 | 7.112 | 0.1793 | 122696.0 | 46100000 | 18100000000 | 7380000000000 | 0.3949 | 0.2434 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0033 | 0.0000 | 0.0135 | 0.0025 | 0.0652 | 0.0246 | 0.1226 | 0.0467 | 0.1086 | 0.0418 | 0.1407 | 0.0563 | 0.5461 | 0.8278 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0061 | 0.0015 | 0.0275 | 0.0178 | 0.0582 | 0.0338 | 0.0453 | 0.0228 | 0.0735 | 0.0336 | 0.7874 | 0.8906 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0061 | 0.0000 | 0.0350 | 0.0000 | 0.1035 | 0.0000 | 0.1461 | 0.0000 | 0.0989 | 0.0000 | 0.1370 | 0.0000 | 0.4718 | 0.0000 | 0.0006 | 0.0025 | 0.0063 | 0.0151 | 0.0753 | 0.0834 | 0.0997 | 0.1173 | 0.5997 | 15 | 19 | 31 | 55 | 87 | 145 | 230 | 323 | 470 | 0.0227 | 19.50 | 5.564 | 0.4886 | 73621.5 | 41900000 | 28500000000 | 21900000000000 | 0.6117 | 0.0866 | 0.0329 | 0.0009 | 0.1078 | 0.0038 | 0.2187 | 0.0509 | 0.1920 | 0.0937 | 0.1694 | 0.1715 | 0.1283 | 0.2068 | 0.0688 | 0.1413 | 0.0431 | 0.1328 | 0.0390 | 0.1983 | 0.0002 | 0.0002 | 0.0004 | 0.0002 | 0.0017 | 0.0009 | 0.0090 | 0.0061 | 0.0363 | 0.0348 | 0.0722 | 0.0563 | 0.0539 | 0.0445 | 0.0705 | 0.0661 | 0.7557 | 0.7909 | 0.0003 | 0.0006 | 0.0018 | 0.0012 | 0.0021 | 0.0033 | 0.0127 | 0.0169 | 0.0496 | 0.0586 | 0.0939 | 0.1112 | 0.0702 | 0.0843 | 0.0915 | 0.0991 | 0.6779 | 0.6248 | 0.0000 | 0.0007 | 0.0017 | 0.0106 | 0.0439 | 0.0866 | 0.0599 | 0.0792 | 0.7175 |