High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 699 | 471 | | 4304 | 9250 | 675.2 | 100.28 | 112.63 | 227.13 | 526 | 609 | 656 | 678 | 694 | 707 | 722 | 740 | 781 | 0.0782 | 723 | 1.058 | 105.04 | 31.11 | 1 | 0.0602 | 259 | 0.0017 | 29.52 | 6.816 | 0.2429 | 465980.0 | 327000000 | 234000000000 | 169000000000000 | 0.4313 | 0.2103 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0028 | 0.0000 | 0.0204 | 0.0139 | 0.0353 | 0.0238 | 0.0311 | 0.0120 | 0.0487 | 0.0205 | 0.8609 | 0.9297 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0149 | 0.0139 | 0.0259 | 0.0238 | 0.0191 | 0.0120 | 0.0254 | 0.0205 | 0.9130 | 0.9297 | 0.0082 | 0.0000 | 0.0163 | 0.0000 | 0.0245 | 0.0000 | 0.0367 | 0.0000 | 0.0816 | 0.0000 | 0.0857 | 0.0000 | 0.0816 | 0.0000 | 0.1143 | 0.0000 | 0.5510 | 0.0000 | 0.0004 | 0.0015 | 0.0038 | 0.0128 | 0.0342 | 0.0556 | 0.0680 | 0.0992 | 0.7244 | 8 | 10 | 12 | 14 | 17 | 26 | 59 | 148 | 341 | 0.1976 | 21.25 | 3.579 | 0.6813 | 64269.9 | 61100000 | 74500000000 | 106000000000000 | 0.4869 | 0.1485 | 0.0430 | 0.0000 | 0.1471 | 0.0171 | 0.1991 | 0.0910 | 0.1222 | 0.1229 | 0.1357 | 0.1456 | 0.1154 | 0.1581 | 0.1086 | 0.1229 | 0.0633 | 0.1024 | 0.0656 | 0.2400 | 0.0000 | 0.0000 | 0.0008 | 0.0004 | 0.0013 | 0.0011 | 0.0109 | 0.0094 | 0.0419 | 0.0410 | 0.0747 | 0.0556 | 0.0516 | 0.0402 | 0.0763 | 0.0676 | 0.7425 | 0.7847 | 0.0000 | 0.0006 | 0.0010 | 0.0022 | 0.0031 | 0.0028 | 0.0175 | 0.0185 | 0.0577 | 0.0612 | 0.0911 | 0.1021 | 0.0695 | 0.0606 | 0.0901 | 0.0948 | 0.6699 | 0.6571 | 0.0000 | 0.0009 | 0.0032 | 0.0125 | 0.0529 | 0.0779 | 0.0682 | 0.0904 | 0.6939 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 318 | 624 | | 6835 | 14487 | 545.4 | 80.10 | 171.75 | 314.77 | 430 | 485 | 516 | 537 | 554 | 568 | 585 | 605 | 635 | 0.0583 | 845 | 0.559 | 146.51 | 30.07 | 3 | 0.0660 | 451 | 0.0011 | 31.34 | 7.160 | 0.2167 | 303826.0 | 173000000 | 99800000000 | 58700000000000 | 0.4423 | 0.2040 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0046 | 0.0007 | 0.0219 | 0.0105 | 0.0376 | 0.0227 | 0.0393 | 0.0121 | 0.0589 | 0.0224 | 0.8363 | 0.9315 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0006 | 0.0138 | 0.0100 | 0.0230 | 0.0208 | 0.0226 | 0.0098 | 0.0272 | 0.0183 | 0.9111 | 0.9405 | 0.0093 | 0.0000 | 0.0163 | 0.0000 | 0.0280 | 0.0000 | 0.0676 | 0.0000 | 0.1189 | 0.0000 | 0.1352 | 0.0000 | 0.1119 | 0.0000 | 0.1119 | 0.0000 | 0.4009 | 0.0000 | 0.0008 | 0.0005 | 0.0050 | 0.0188 | 0.0379 | 0.0636 | 0.0767 | 0.0981 | 0.6986 | 11 | 13 | 15 | 19 | 25 | 47 | 102 | 252 | 575 | 0.1437 | 10.43 | 3.781 | 0.6289 | 128574.0 | 142000000 | 187000000000 | 273000000000000 | 0.3937 | 0.2546 | 0.0244 | 0.0022 | 0.0822 | 0.0126 | 0.1735 | 0.0445 | 0.1903 | 0.0867 | 0.2116 | 0.1890 | 0.1248 | 0.1883 | 0.0868 | 0.1401 | 0.0715 | 0.1371 | 0.0350 | 0.1994 | 0.0000 | 0.0005 | 0.0010 | 0.0007 | 0.0036 | 0.0030 | 0.0067 | 0.0079 | 0.0359 | 0.0345 | 0.0508 | 0.0483 | 0.0398 | 0.0391 | 0.0646 | 0.0606 | 0.7976 | 0.8055 | 0.0009 | 0.0007 | 0.0009 | 0.0010 | 0.0028 | 0.0020 | 0.0080 | 0.0081 | 0.0423 | 0.0430 | 0.0537 | 0.0696 | 0.0515 | 0.0545 | 0.0771 | 0.0794 | 0.7628 | 0.7418 | 0.0006 | 0.0014 | 0.0023 | 0.0093 | 0.0369 | 0.0544 | 0.0417 | 0.0668 | 0.7866 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 854 | 416 | | 11131 | 15417 | 454.3 | 71.88 | 90.38 | 157.98 | 358 | 393 | 418 | 438 | 454 | 468 | 484 | 508 | 549 | 0.0688 | 1061 | 1.159 | 147.22 | 49.48 | 2 | 0.0314 | 350 | 0.0013 | 17.13 | 6.964 | 0.2615 | 211570.0 | 101000000 | 49300000000 | 24600000000000 | 0.4019 | 0.2435 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0025 | 0.0005 | 0.0056 | 0.0007 | 0.0198 | 0.0107 | 0.0364 | 0.0188 | 0.0370 | 0.0124 | 0.0542 | 0.0178 | 0.8429 | 0.9388 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0023 | 0.0002 | 0.0110 | 0.0093 | 0.0213 | 0.0169 | 0.0198 | 0.0089 | 0.0278 | 0.0138 | 0.9153 | 0.9509 | 0.0058 | 0.0159 | 0.0075 | 0.0397 | 0.0100 | 0.0556 | 0.0325 | 0.1270 | 0.0600 | 0.0873 | 0.0783 | 0.1349 | 0.0666 | 0.1111 | 0.0966 | 0.0952 | 0.6428 | 0.3333 | 0.0012 | 0.0023 | 0.0068 | 0.0178 | 0.0371 | 0.0570 | 0.0697 | 0.0892 | 0.7189 | 7 | 9 | 10 | 11 | 14 | 23 | 53 | 139 | 311 | 0.2296 | 12.11 | 3.590 | 0.7091 | 33126.6 | 17600000 | 11100000000 | 7920000000000 | 0.5835 | 0.1060 | 0.0228 | 0.0066 | 0.0791 | 0.0185 | 0.1263 | 0.0524 | 0.1948 | 0.0739 | 0.1933 | 0.1344 | 0.1522 | 0.1839 | 0.0898 | 0.1440 | 0.0883 | 0.1322 | 0.0533 | 0.2541 | 0.0000 | 0.0006 | 0.0012 | 0.0017 | 0.0021 | 0.0039 | 0.0062 | 0.0067 | 0.0321 | 0.0323 | 0.0482 | 0.0424 | 0.0349 | 0.0336 | 0.0634 | 0.0528 | 0.8120 | 0.8259 | 0.0011 | 0.0003 | 0.0031 | 0.0018 | 0.0025 | 0.0028 | 0.0098 | 0.0104 | 0.0419 | 0.0429 | 0.0613 | 0.0726 | 0.0526 | 0.0643 | 0.0793 | 0.0867 | 0.7482 | 0.7182 | 0.0003 | 0.0013 | 0.0028 | 0.0103 | 0.0339 | 0.0573 | 0.0419 | 0.0637 | 0.7885 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1249 | 769 | | 4803 | 11247 | 502.2 | 83.00 | 67.05 | 122.38 | 382 | 431 | 463 | 488 | 508 | 528 | 552 | 579 | 608 | 0.0648 | 729 | 1.156 | 88.46 | 33.06 | 1 | 0.0477 | 229 | 0.0014 | 23.98 | 6.830 | 0.2358 | 259094.0 | 137000000 | 73800000000 | 40500000000000 | 0.4284 | 0.2133 | 0.0011 | 0.0000 | 0.0019 | 0.0000 | 0.0044 | 0.0000 | 0.0091 | 0.0002 | 0.0299 | 0.0136 | 0.0517 | 0.0206 | 0.0575 | 0.0124 | 0.0811 | 0.0183 | 0.7632 | 0.9350 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0002 | 0.0170 | 0.0136 | 0.0276 | 0.0206 | 0.0218 | 0.0124 | 0.0377 | 0.0183 | 0.8937 | 0.9350 | 0.0072 | 0.0000 | 0.0181 | 0.0000 | 0.0325 | 0.0000 | 0.0597 | 0.0000 | 0.0868 | 0.0000 | 0.1374 | 0.0000 | 0.1230 | 0.0000 | 0.1754 | 0.0000 | 0.3599 | 0.0000 | 0.0019 | 0.0016 | 0.0054 | 0.0140 | 0.0384 | 0.0594 | 0.0602 | 0.0889 | 0.7301 | 6 | 8 | 10 | 12 | 15 | 20 | 38 | 86 | 207 | 0.1665 | 6.51 | 3.350 | 0.6502 | 19470.7 | 8860000 | 4860000000 | 2970000000000 | 0.5816 | 0.0962 | 0.0324 | 0.0043 | 0.1477 | 0.0208 | 0.2216 | 0.0720 | 0.2090 | 0.1276 | 0.1658 | 0.1753 | 0.1189 | 0.1840 | 0.0613 | 0.1372 | 0.0216 | 0.1345 | 0.0216 | 0.1441 | 0.0007 | 0.0003 | 0.0010 | 0.0009 | 0.0034 | 0.0039 | 0.0172 | 0.0128 | 0.0540 | 0.0538 | 0.0890 | 0.0805 | 0.0639 | 0.0589 | 0.0907 | 0.0838 | 0.6801 | 0.7050 | 0.0000 | 0.0005 | 0.0013 | 0.0019 | 0.0030 | 0.0033 | 0.0166 | 0.0196 | 0.0675 | 0.0650 | 0.0968 | 0.1182 | 0.0739 | 0.0715 | 0.0994 | 0.1005 | 0.6416 | 0.6196 | 0.0004 | 0.0015 | 0.0034 | 0.0145 | 0.0574 | 0.1015 | 0.0624 | 0.0915 | 0.6673 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 817 | | 5202 | 13328 | 498.6 | 85.62 | 75.42 | 193.51 | 376 | 424 | 460 | 483 | 503 | 525 | 551 | 573 | 600 | 0.0606 | 808 | 0.924 | 121.38 | 32.28 | 1 | 0.0600 | 312 | 0.0016 | 14.59 | 6.726 | 0.2939 | 255905.0 | 135000000 | 72700000000 | 40000000000000 | 0.4179 | 0.2243 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0023 | 0.0002 | 0.0100 | 0.0010 | 0.0267 | 0.0117 | 0.0460 | 0.0271 | 0.0409 | 0.0125 | 0.0779 | 0.0230 | 0.7949 | 0.9246 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0041 | 0.0008 | 0.0129 | 0.0112 | 0.0226 | 0.0247 | 0.0142 | 0.0106 | 0.0293 | 0.0185 | 0.9158 | 0.9342 | 0.0074 | 0.0227 | 0.0185 | 0.0000 | 0.0444 | 0.0455 | 0.0628 | 0.0455 | 0.0795 | 0.1591 | 0.1109 | 0.1364 | 0.1146 | 0.1136 | 0.1109 | 0.1364 | 0.4510 | 0.3409 | 0.0022 | 0.0041 | 0.0081 | 0.0144 | 0.0276 | 0.0398 | 0.0446 | 0.0692 | 0.7901 | 8 | 10 | 11 | 12 | 14 | 17 | 27 | 59 | 186 | 0.2830 | 9.88 | 2.941 | 0.7317 | 43131.2 | 46900000 | 63500000000 | 95400000000000 | 0.3571 | 0.2342 | 0.0717 | 0.0047 | 0.2131 | 0.0292 | 0.2384 | 0.1318 | 0.1751 | 0.1111 | 0.1245 | 0.1770 | 0.0802 | 0.2062 | 0.0422 | 0.1234 | 0.0295 | 0.1036 | 0.0253 | 0.1130 | 0.0008 | 0.0003 | 0.0011 | 0.0036 | 0.0019 | 0.0062 | 0.0121 | 0.0147 | 0.0524 | 0.0421 | 0.0746 | 0.0718 | 0.0543 | 0.0492 | 0.0758 | 0.0744 | 0.7271 | 0.7378 | 0.0000 | 0.0005 | 0.0009 | 0.0010 | 0.0023 | 0.0025 | 0.0138 | 0.0125 | 0.0555 | 0.0609 | 0.0909 | 0.0973 | 0.0564 | 0.0579 | 0.0844 | 0.0868 | 0.6957 | 0.6806 | 0.0004 | 0.0017 | 0.0008 | 0.0138 | 0.0522 | 0.0823 | 0.0547 | 0.0852 | 0.7090 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 431 | 339 | | 3943 | 10483 | 650.4 | 93.20 | 77.12 | 134.86 | 524 | 578 | 611 | 637 | 655 | 676 | 697 | 725 | 765 | 0.0630 | 660 | 1.066 | 99.30 | 32.65 | 1 | 0.0621 | 245 | 0.0013 | 29.21 | 6.926 | 0.2389 | 431670.0 | 292000000 | 201000000000 | 140000000000000 | 0.4337 | 0.2092 | 0.0006 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0043 | 0.0003 | 0.0239 | 0.0147 | 0.0347 | 0.0234 | 0.0340 | 0.0127 | 0.0534 | 0.0226 | 0.8476 | 0.9264 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0003 | 0.0148 | 0.0147 | 0.0235 | 0.0234 | 0.0179 | 0.0127 | 0.0277 | 0.0226 | 0.9140 | 0.9264 | 0.0065 | 0.0000 | 0.0065 | 0.0000 | 0.0226 | 0.0000 | 0.0355 | 0.0000 | 0.1000 | 0.0000 | 0.0871 | 0.0000 | 0.1065 | 0.0000 | 0.1290 | 0.0000 | 0.5065 | 0.0000 | 0.0000 | 0.0038 | 0.0072 | 0.0191 | 0.0401 | 0.0558 | 0.0615 | 0.0873 | 0.7252 | 6 | 8 | 9 | 11 | 14 | 22 | 53 | 125 | 238 | 0.1380 | 10.00 | 3.574 | 0.6077 | 24132.5 | 11700000 | 7110000000 | 4930000000000 | 0.4308 | 0.2239 | 0.0546 | 0.0060 | 0.1513 | 0.0313 | 0.2122 | 0.0625 | 0.1912 | 0.1159 | 0.1639 | 0.1915 | 0.1261 | 0.1935 | 0.0630 | 0.1381 | 0.0315 | 0.1190 | 0.0063 | 0.1421 | 0.0010 | 0.0000 | 0.0017 | 0.0015 | 0.0024 | 0.0033 | 0.0102 | 0.0118 | 0.0453 | 0.0386 | 0.0572 | 0.0477 | 0.0437 | 0.0443 | 0.0670 | 0.0641 | 0.7716 | 0.7887 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0020 | 0.0017 | 0.0113 | 0.0139 | 0.0577 | 0.0582 | 0.0658 | 0.0747 | 0.0516 | 0.0595 | 0.0791 | 0.0860 | 0.7313 | 0.7059 | 0.0004 | 0.0000 | 0.0015 | 0.0127 | 0.0470 | 0.0601 | 0.0548 | 0.0660 | 0.7576 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 287 | 208 | | 5091 | 12471 | 474.1 | 73.02 | 68.38 | 135.66 | 363 | 414 | 452 | 475 | 490 | 504 | 518 | 533 | 553 | 0.0763 | 952 | 1.174 | 64.62 | 19.85 | 1 | 0.0297 | 151 | 0.0020 | 19.65 | 6.571 | 0.2736 | 230087.0 | 114000000 | 57200000000 | 29100000000000 | 0.4330 | 0.2034 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0074 | 0.0012 | 0.0203 | 0.0121 | 0.0432 | 0.0234 | 0.0404 | 0.0127 | 0.0650 | 0.0183 | 0.8215 | 0.9322 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0032 | 0.0012 | 0.0131 | 0.0121 | 0.0257 | 0.0234 | 0.0181 | 0.0127 | 0.0235 | 0.0183 | 0.9163 | 0.9322 | 0.0328 | 0.0000 | 0.0615 | 0.0000 | 0.1025 | 0.0000 | 0.1311 | 0.0000 | 0.1352 | 0.0000 | 0.1352 | 0.0000 | 0.1230 | 0.0000 | 0.0820 | 0.0000 | 0.1967 | 0.0000 | 0.0000 | 0.0026 | 0.0065 | 0.0091 | 0.0308 | 0.0587 | 0.0532 | 0.0834 | 0.7557 | 6 | 8 | 9 | 11 | 15 | 21 | 36 | 71 | 216 | 0.1260 | 12.46 | 3.408 | 0.6217 | 23078.9 | 13100000 | 9690000000 | 8870000000000 | 0.4949 | 0.1599 | 0.0417 | 0.0057 | 0.1106 | 0.0278 | 0.1571 | 0.0785 | 0.1234 | 0.0849 | 0.1619 | 0.1091 | 0.1250 | 0.1320 | 0.1106 | 0.1084 | 0.1090 | 0.1434 | 0.0609 | 0.3103 | 0.0024 | 0.0014 | 0.0044 | 0.0028 | 0.0051 | 0.0068 | 0.0139 | 0.0160 | 0.0493 | 0.0376 | 0.0748 | 0.0673 | 0.0479 | 0.0450 | 0.0816 | 0.0730 | 0.7206 | 0.7501 | 0.0000 | 0.0014 | 0.0017 | 0.0009 | 0.0043 | 0.0047 | 0.0181 | 0.0161 | 0.0513 | 0.0584 | 0.0945 | 0.1011 | 0.0513 | 0.0570 | 0.0815 | 0.0783 | 0.6972 | 0.6820 | 0.0008 | 0.0012 | 0.0043 | 0.0152 | 0.0519 | 0.0831 | 0.0542 | 0.0807 | 0.7087 | ||
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 828 | 731 | | 4916 | 17078 | 344.5 | 49.98 | 70.06 | 109.17 | 278 | 302 | 316 | 330 | 344 | 358 | 374 | 391 | 410 | 0.0440 | 752 | 0.700 | 121.80 | 29.61 | 2 | 0.0728 | 358 | 0.0032 | 8.09 | 6.021 | 0.3596 | 121208.0 | 43500000 | 15900000000 | 5900000000000 | 0.4249 | 0.2173 | 0.0002 | 0.0000 | 0.0015 | 0.0000 | 0.0045 | 0.0000 | 0.0067 | 0.0000 | 0.0270 | 0.0128 | 0.0399 | 0.0214 | 0.0394 | 0.0128 | 0.0789 | 0.0218 | 0.8018 | 0.9312 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0027 | 0.0000 | 0.0144 | 0.0128 | 0.0229 | 0.0214 | 0.0200 | 0.0128 | 0.0328 | 0.0185 | 0.9062 | 0.9345 | 0.0187 | 1.0000 | 0.0258 | 0.0000 | 0.0328 | 0.0000 | 0.0562 | 0.0000 | 0.1007 | 0.0000 | 0.1499 | 0.0000 | 0.1288 | 0.0000 | 0.1241 | 0.0000 | 0.3630 | 0.0000 | 0.0021 | 0.0041 | 0.0062 | 0.0144 | 0.0299 | 0.0533 | 0.0545 | 0.0685 | 0.7671 | 6 | 8 | 10 | 11 | 14 | 26 | 60 | 123 | 221 | 0.1196 | 5.30 | 3.437 | 0.5812 | 16825.5 | 6090000 | 2810000000 | 1590000000000 | 0.3847 | 0.2364 | 0.0327 | 0.0062 | 0.1401 | 0.0166 | 0.2424 | 0.0916 | 0.2139 | 0.1211 | 0.1718 | 0.1868 | 0.1149 | 0.2002 | 0.0516 | 0.1454 | 0.0263 | 0.1174 | 0.0063 | 0.1148 | 0.0000 | 0.0005 | 0.0006 | 0.0010 | 0.0023 | 0.0019 | 0.0083 | 0.0103 | 0.0391 | 0.0317 | 0.0712 | 0.0567 | 0.0463 | 0.0437 | 0.0805 | 0.0695 | 0.7518 | 0.7849 | 0.0000 | 0.0000 | 0.0009 | 0.0013 | 0.0021 | 0.0033 | 0.0145 | 0.0170 | 0.0532 | 0.0625 | 0.0907 | 0.0938 | 0.0628 | 0.0780 | 0.0937 | 0.1001 | 0.6822 | 0.6441 | 0.0004 | 0.0002 | 0.0032 | 0.0122 | 0.0464 | 0.0780 | 0.0622 | 0.0900 | 0.7075 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 465 | 643 | | 8720 | 12380 | 327.7 | 56.71 | 178.47 | 263.33 | 253 | 288 | 306 | 320 | 333 | 346 | 358 | 371 | 394 | 0.0826 | 1023 | 1.053 | 189.34 | 55.01 | 1 | 0.0515 | 449 | 0.0016 | 19.71 | 6.739 | 0.2552 | 110617.0 | 38300000 | 13500000000 | 4860000000000 | 0.4132 | 0.2316 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0010 | 0.0001 | 0.0059 | 0.0010 | 0.0246 | 0.0101 | 0.0541 | 0.0199 | 0.0557 | 0.0130 | 0.0950 | 0.0226 | 0.7636 | 0.9332 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0001 | 0.0030 | 0.0009 | 0.0126 | 0.0096 | 0.0228 | 0.0178 | 0.0228 | 0.0096 | 0.0370 | 0.0162 | 0.9017 | 0.9456 | 0.0114 | 0.0000 | 0.0227 | 0.0000 | 0.0272 | 0.0000 | 0.0681 | 0.0000 | 0.0988 | 0.0000 | 0.1703 | 0.0000 | 0.1067 | 0.0000 | 0.1226 | 0.0000 | 0.3723 | 0.0000 | 0.0008 | 0.0019 | 0.0071 | 0.0173 | 0.0483 | 0.0854 | 0.0861 | 0.1201 | 0.6330 | 18 | 25 | 36 | 52 | 72 | 98 | 148 | 262 | 503 | 0.0250 | 35.86 | 5.284 | 0.5431 | 101188.0 | 92200000 | 104000000000 | 133000000000000 | 0.5504 | 0.1103 | 0.0118 | 0.0028 | 0.0634 | 0.0052 | 0.1160 | 0.0282 | 0.1461 | 0.0612 | 0.1912 | 0.1266 | 0.1751 | 0.1507 | 0.1224 | 0.1351 | 0.0988 | 0.1573 | 0.0752 | 0.3329 | 0.0005 | 0.0002 | 0.0003 | 0.0011 | 0.0024 | 0.0023 | 0.0079 | 0.0094 | 0.0482 | 0.0428 | 0.0854 | 0.0656 | 0.0514 | 0.0563 | 0.0801 | 0.0808 | 0.7238 | 0.7415 | 0.0000 | 0.0000 | 0.0021 | 0.0008 | 0.0042 | 0.0035 | 0.0101 | 0.0097 | 0.0538 | 0.0635 | 0.0894 | 0.0884 | 0.0594 | 0.0666 | 0.0876 | 0.0970 | 0.6934 | 0.6706 | 0.0000 | 0.0003 | 0.0031 | 0.0089 | 0.0520 | 0.0851 | 0.0560 | 0.0875 | 0.7072 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 170 | 550 | | 8750 | 8424 | 502.4 | 87.96 | 41.36 | 73.23 | 382 | 421 | 449 | 477 | 504 | 533 | 561 | 587 | 616 | 0.0991 | 835 | 0.776 | 84.48 | 24.52 | 5 | 0.0277 | 242 | 0.0010 | 31.96 | 7.187 | 0.2170 | 260103.0 | 138000000 | 75400000000 | 41900000000000 | 0.4172 | 0.2234 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0032 | 0.0000 | 0.0111 | 0.0005 | 0.0476 | 0.0114 | 0.0760 | 0.0187 | 0.0904 | 0.0131 | 0.1317 | 0.0244 | 0.6373 | 0.9319 | 0.0003 | 0.0000 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0005 | 0.0214 | 0.0113 | 0.0331 | 0.0183 | 0.0365 | 0.0119 | 0.0525 | 0.0214 | 0.8509 | 0.9367 | 0.0126 | 0.1000 | 0.0126 | 0.2000 | 0.0356 | 0.5000 | 0.0617 | 0.2000 | 0.1146 | 0.0000 | 0.1486 | 0.0000 | 0.1328 | 0.0000 | 0.1518 | 0.0000 | 0.3296 | 0.0000 | 0.0014 | 0.0023 | 0.0063 | 0.0160 | 0.0405 | 0.0657 | 0.0673 | 0.0822 | 0.7184 | 8 | 10 | 12 | 13 | 16 | 20 | 28 | 44 | 98 | 0.1584 | 2.61 | 3.052 | 0.7597 | 7073.0 | 2420000 | 1080000000 | 547000000000 | 0.6438 | 0.0750 | 0.0266 | 0.0119 | 0.0620 | 0.0252 | 0.1004 | 0.0365 | 0.1492 | 0.0697 | 0.1905 | 0.1048 | 0.1418 | 0.1287 | 0.1536 | 0.1301 | 0.0960 | 0.1858 | 0.0798 | 0.3072 | 0.0055 | 0.0063 | 0.0104 | 0.0116 | 0.0127 | 0.0137 | 0.0209 | 0.0256 | 0.0563 | 0.0460 | 0.0700 | 0.0674 | 0.0691 | 0.0593 | 0.1004 | 0.1092 | 0.6547 | 0.6608 | 0.0000 | 0.0045 | 0.0052 | 0.0037 | 0.0085 | 0.0082 | 0.0184 | 0.0231 | 0.0636 | 0.0723 | 0.0932 | 0.0835 | 0.0636 | 0.0776 | 0.1122 | 0.1148 | 0.6352 | 0.6122 | 0.0011 | 0.0038 | 0.0098 | 0.0235 | 0.0573 | 0.0742 | 0.0770 | 0.1070 | 0.6463 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 489 | 816 | | 9613 | 19666 | 390.1 | 60.27 | 175.40 | 251.54 | 316 | 341 | 358 | 372 | 386 | 400 | 417 | 439 | 471 | 0.0499 | 981 | 1.140 | 113.53 | 39.96 | 1 | 0.0287 | 276 | 0.0011 | 38.49 | 7.151 | 0.1882 | 155802.0 | 63700000 | 26600000000 | 11400000000000 | 0.4343 | 0.2166 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0063 | 0.0003 | 0.0283 | 0.0097 | 0.0643 | 0.0203 | 0.0756 | 0.0131 | 0.1055 | 0.0246 | 0.7186 | 0.9320 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0028 | 0.0001 | 0.0131 | 0.0084 | 0.0304 | 0.0170 | 0.0306 | 0.0084 | 0.0456 | 0.0152 | 0.8770 | 0.9508 | 0.0087 | 0.0000 | 0.0135 | 0.0000 | 0.0279 | 0.0000 | 0.0983 | 0.0000 | 0.1387 | 0.0000 | 0.1513 | 0.0000 | 0.1416 | 0.0000 | 0.1262 | 0.0000 | 0.2938 | 0.0000 | 0.0011 | 0.0035 | 0.0104 | 0.0298 | 0.0782 | 0.1108 | 0.1017 | 0.1210 | 0.5436 | 14 | 16 | 20 | 33 | 69 | 120 | 189 | 295 | 474 | 0.0394 | 31.15 | 5.368 | 0.5068 | 94034.5 | 84100000 | 103000000000 | 154000000000000 | 0.3897 | 0.2589 | 0.0213 | 0.0011 | 0.1385 | 0.0082 | 0.2420 | 0.0616 | 0.1776 | 0.1065 | 0.1672 | 0.1616 | 0.1236 | 0.1947 | 0.0759 | 0.1312 | 0.0374 | 0.1260 | 0.0167 | 0.2092 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0018 | 0.0009 | 0.0087 | 0.0075 | 0.0520 | 0.0374 | 0.0873 | 0.0660 | 0.0601 | 0.0490 | 0.0912 | 0.0703 | 0.6988 | 0.7683 | 0.0002 | 0.0002 | 0.0016 | 0.0006 | 0.0035 | 0.0034 | 0.0199 | 0.0226 | 0.0723 | 0.0866 | 0.1159 | 0.1289 | 0.0783 | 0.0860 | 0.1143 | 0.1210 | 0.5940 | 0.5507 | 0.0000 | 0.0008 | 0.0022 | 0.0144 | 0.0633 | 0.0998 | 0.0700 | 0.1025 | 0.6469 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 308 | 884 | | 5050 | 10182 | 749.7 | 126.97 | 42.65 | 71.54 | 594 | 652 | 686 | 713 | 737 | 762 | 805 | 871 | 942 | 0.0693 | 706 | 1.198 | 99.81 | 37.54 | 1 | 0.0493 | 249 | 0.0009 | 44.07 | 7.331 | 0.2040 | 578151.0 | 458000000 | 371000000000 | 308000000000000 | 0.4226 | 0.2196 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0068 | 0.0006 | 0.0285 | 0.0120 | 0.0415 | 0.0212 | 0.0388 | 0.0132 | 0.0616 | 0.0186 | 0.8190 | 0.9345 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0020 | 0.0006 | 0.0159 | 0.0120 | 0.0237 | 0.0212 | 0.0190 | 0.0116 | 0.0326 | 0.0178 | 0.9061 | 0.9369 | 0.0036 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0169 | 1.0000 | 0.0495 | 0.0000 | 0.0579 | 0.0000 | 0.0760 | 0.0000 | 0.0893 | 0.0000 | 0.7045 | 0.0000 | 0.0027 | 0.0054 | 0.0125 | 0.0152 | 0.0411 | 0.0438 | 0.0585 | 0.0688 | 0.7520 | 6 | 8 | 9 | 11 | 13 | 19 | 36 | 60 | 109 | 0.1640 | 2.95 | 2.935 | 0.7102 | 6935.9 | 2170000 | 941000000 | 501000000000 | 0.4404 | 0.1899 | 0.0194 | 0.0075 | 0.0535 | 0.0125 | 0.1069 | 0.0337 | 0.1470 | 0.0580 | 0.1701 | 0.1079 | 0.1750 | 0.1341 | 0.1665 | 0.1248 | 0.1130 | 0.1622 | 0.0486 | 0.3593 | 0.0013 | 0.0014 | 0.0041 | 0.0022 | 0.0048 | 0.0064 | 0.0153 | 0.0160 | 0.0396 | 0.0329 | 0.0616 | 0.0440 | 0.0517 | 0.0442 | 0.0727 | 0.0650 | 0.7490 | 0.7879 | 0.0017 | 0.0020 | 0.0043 | 0.0035 | 0.0108 | 0.0055 | 0.0208 | 0.0179 | 0.0554 | 0.0546 | 0.0705 | 0.0789 | 0.0575 | 0.0645 | 0.0809 | 0.0904 | 0.6981 | 0.6827 | 0.0015 | 0.0037 | 0.0104 | 0.0186 | 0.0443 | 0.0707 | 0.0592 | 0.0878 | 0.7039 | ||
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 945 | 791 | | 7136 | 8653 | 396.4 | 68.86 | 331.09 | 487.17 | 292 | 338 | 365 | 386 | 406 | 423 | 439 | 454 | 478 | 0.0953 | 825 | 1.046 | 109.66 | 38.48 | 6 | 0.0419 | 299 | 0.0024 | 9.08 | 6.362 | 0.3660 | 161888.0 | 67800000 | 29000000000 | 12700000000000 | 0.4181 | 0.2153 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0038 | 0.0000 | 0.0079 | 0.0011 | 0.0218 | 0.0106 | 0.0533 | 0.0271 | 0.0385 | 0.0132 | 0.0585 | 0.0186 | 0.8142 | 0.9294 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0011 | 0.0113 | 0.0105 | 0.0289 | 0.0260 | 0.0141 | 0.0119 | 0.0204 | 0.0173 | 0.9222 | 0.9333 | 0.0066 | 0.0000 | 0.0066 | 0.0000 | 0.0263 | 0.0000 | 0.0447 | 0.0000 | 0.1092 | 0.0000 | 0.1184 | 0.0000 | 0.1158 | 0.0000 | 0.1382 | 0.0000 | 0.4342 | 0.0000 | 0.0005 | 0.0015 | 0.0051 | 0.0101 | 0.0281 | 0.0398 | 0.0367 | 0.0529 | 0.8252 | 10 | 12 | 15 | 26 | 85 | 211 | 381 | 631 | 998 | 0.1055 | 26.80 | 5.014 | 0.5502 | 346927.0 | 541000000 | 1110000000000 | 2.77E+15 | 0.4761 | 0.1685 | 0.0161 | 0.0031 | 0.0966 | 0.0086 | 0.1804 | 0.0350 | 0.1739 | 0.0871 | 0.1643 | 0.1540 | 0.1433 | 0.1882 | 0.0934 | 0.1407 | 0.0805 | 0.1198 | 0.0515 | 0.2636 | 0.0003 | 0.0008 | 0.0006 | 0.0014 | 0.0025 | 0.0017 | 0.0063 | 0.0068 | 0.0348 | 0.0256 | 0.0659 | 0.0501 | 0.0446 | 0.0400 | 0.0681 | 0.0535 | 0.7768 | 0.8202 | 0.0000 | 0.0004 | 0.0004 | 0.0018 | 0.0039 | 0.0049 | 0.0102 | 0.0123 | 0.0481 | 0.0511 | 0.0777 | 0.0886 | 0.0560 | 0.0675 | 0.0765 | 0.0825 | 0.7272 | 0.6909 | 0.0000 | 0.0004 | 0.0036 | 0.0093 | 0.0411 | 0.0750 | 0.0496 | 0.0650 | 0.7562 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 372 | 900 | | 5044 | 9324 | 570.5 | 98.09 | 110.30 | 193.81 | 423 | 504 | 548 | 574 | 591 | 608 | 625 | 644 | 675 | 0.0741 | 691 | 0.949 | 144.16 | 41.87 | 3 | 0.0765 | 386 | 0.0009 | 58.08 | 7.313 | 0.1858 | 335121.0 | 201000000 | 123000000000 | 76200000000000 | 0.4530 | 0.1918 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0002 | 0.0055 | 0.0012 | 0.0271 | 0.0139 | 0.0472 | 0.0212 | 0.0462 | 0.0133 | 0.0650 | 0.0234 | 0.8066 | 0.9268 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0018 | 0.0012 | 0.0148 | 0.0139 | 0.0237 | 0.0212 | 0.0189 | 0.0133 | 0.0283 | 0.0218 | 0.9121 | 0.9285 | 0.0051 | 1.0000 | 0.0204 | 0.0000 | 0.0382 | 0.0000 | 0.0789 | 0.0000 | 0.1399 | 0.0000 | 0.1527 | 0.0000 | 0.1425 | 0.0000 | 0.1552 | 0.0000 | 0.2672 | 0.0000 | 0.0006 | 0.0016 | 0.0039 | 0.0132 | 0.0319 | 0.0631 | 0.0673 | 0.0879 | 0.7304 | 13 | 15 | 17 | 20 | 24 | 37 | 65 | 143 | 347 | 0.2499 | 4.68 | 3.068 | 0.7533 | 49725.0 | 35000000 | 30000000000 | 29200000000000 | 0.6863 | 0.0611 | 0.0201 | 0.0070 | 0.0828 | 0.0120 | 0.2081 | 0.0468 | 0.1834 | 0.0807 | 0.1969 | 0.1723 | 0.1454 | 0.1912 | 0.0805 | 0.1524 | 0.0403 | 0.1404 | 0.0425 | 0.1972 | 0.0004 | 0.0022 | 0.0004 | 0.0022 | 0.0021 | 0.0065 | 0.0116 | 0.0151 | 0.0418 | 0.0391 | 0.0708 | 0.0613 | 0.0472 | 0.0459 | 0.0911 | 0.0911 | 0.7345 | 0.7368 | 0.0000 | 0.0006 | 0.0005 | 0.0006 | 0.0051 | 0.0011 | 0.0142 | 0.0146 | 0.0524 | 0.0611 | 0.0956 | 0.0952 | 0.0478 | 0.0538 | 0.0935 | 0.0947 | 0.6909 | 0.6784 | 0.0000 | 0.0000 | 0.0019 | 0.0116 | 0.0551 | 0.0811 | 0.0487 | 0.0982 | 0.7034 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 149 | 240 | | 6671 | 12334 | 390.0 | 50.74 | 109.56 | 270.04 | 317 | 352 | 374 | 389 | 399 | 409 | 419 | 431 | 446 | 0.0712 | 878 | 0.700 | 125.40 | 29.61 | 3 | 0.0475 | 317 | 0.0019 | 22.81 | 6.624 | 0.2349 | 154695.0 | 62200000 | 25300000000 | 10400000000000 | 0.4580 | 0.1948 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0037 | 0.0003 | 0.0169 | 0.0112 | 0.0407 | 0.0210 | 0.0412 | 0.0134 | 0.0715 | 0.0187 | 0.8249 | 0.9354 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0023 | 0.0003 | 0.0133 | 0.0112 | 0.0316 | 0.0210 | 0.0235 | 0.0134 | 0.0319 | 0.0187 | 0.8969 | 0.9354 | 0.1176 | 0.0000 | 0.1438 | 0.0000 | 0.1373 | 0.0000 | 0.1830 | 0.0000 | 0.1111 | 0.0000 | 0.1569 | 0.0000 | 0.0261 | 0.0000 | 0.0523 | 0.0000 | 0.0719 | 0.0000 | 0.0020 | 0.0033 | 0.0091 | 0.0202 | 0.0463 | 0.0663 | 0.0825 | 0.1189 | 0.6514 | 9 | 11 | 12 | 14 | 15 | 18 | 24 | 59 | 344 | 0.2142 | 6.81 | 2.736 | 0.6641 | 84919.1 | 101000000 | 144000000000 | 229000000000000 | 0.5929 | 0.1077 | 0.0204 | 0.0068 | 0.0980 | 0.0068 | 0.1592 | 0.0492 | 0.1878 | 0.0881 | 0.2082 | 0.1593 | 0.1755 | 0.1864 | 0.1020 | 0.1203 | 0.0367 | 0.1661 | 0.0122 | 0.2169 | 0.0005 | 0.0017 | 0.0019 | 0.0004 | 0.0014 | 0.0034 | 0.0052 | 0.0085 | 0.0331 | 0.0296 | 0.0553 | 0.0525 | 0.0355 | 0.0407 | 0.0766 | 0.0805 | 0.7905 | 0.7827 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0021 | 0.0017 | 0.0064 | 0.0079 | 0.0380 | 0.0350 | 0.0545 | 0.0599 | 0.0401 | 0.0418 | 0.0866 | 0.0870 | 0.7722 | 0.7662 | 0.0000 | 0.0000 | 0.0020 | 0.0076 | 0.0289 | 0.0613 | 0.0370 | 0.0770 | 0.7863 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1218 | 150 | | 8328 | 20825 | 278.7 | 60.80 | 290.87 | 439.80 | 204 | 240 | 258 | 272 | 285 | 298 | 311 | 327 | 347 | 0.0520 | 1082 | 0.814 | 131.22 | 25.94 | 2 | 0.0359 | 299 | 0.0015 | 25.68 | 6.861 | 0.2311 | 81369.2 | 24600000 | 7610000000 | 2410000000000 | 0.4056 | 0.2353 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0106 | 0.0006 | 0.0413 | 0.0112 | 0.0811 | 0.0241 | 0.0864 | 0.0135 | 0.1377 | 0.0258 | 0.6381 | 0.9247 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0001 | 0.0143 | 0.0100 | 0.0289 | 0.0185 | 0.0247 | 0.0084 | 0.0466 | 0.0146 | 0.8830 | 0.9483 | 0.0055 | 0.0364 | 0.0234 | 0.0182 | 0.0343 | 0.0455 | 0.0810 | 0.1273 | 0.1262 | 0.1364 | 0.1752 | 0.3091 | 0.1371 | 0.0909 | 0.1269 | 0.0727 | 0.2905 | 0.1636 | 0.0015 | 0.0033 | 0.0074 | 0.0220 | 0.0435 | 0.0863 | 0.0844 | 0.1177 | 0.6340 | 7 | 10 | 13 | 17 | 28 | 115 | 308 | 594 | 1020 | 0.0848 | 69.35 | 5.353 | 0.4886 | 278017.0 | 336000000 | 456000000000 | 669000000000000 | 0.5138 | 0.1645 | 0.0468 | 0.0052 | 0.1680 | 0.0170 | 0.2305 | 0.1168 | 0.1460 | 0.1394 | 0.1433 | 0.1748 | 0.1148 | 0.1667 | 0.0661 | 0.1295 | 0.0487 | 0.1130 | 0.0358 | 0.1375 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0009 | 0.0009 | 0.0078 | 0.0073 | 0.0402 | 0.0330 | 0.0717 | 0.0659 | 0.0532 | 0.0476 | 0.0763 | 0.0708 | 0.7497 | 0.7740 | 0.0002 | 0.0011 | 0.0003 | 0.0020 | 0.0034 | 0.0050 | 0.0145 | 0.0131 | 0.0489 | 0.0487 | 0.0799 | 0.0830 | 0.0597 | 0.0625 | 0.0824 | 0.0882 | 0.7106 | 0.6963 | 0.0002 | 0.0002 | 0.0019 | 0.0108 | 0.0438 | 0.0821 | 0.0547 | 0.0780 | 0.7283 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 910 | 235 | | 5650 | 9484 | 613.1 | 99.25 | 15.85 | 17.71 | 472 | 537 | 575 | 601 | 623 | 643 | 663 | 690 | 733 | 0.0777 | 737 | 0.760 | 87.05 | 15.26 | 1 | 0.0388 | 219 | 0.0011 | 30.87 | 7.107 | 0.2252 | 385716.0 | 248000000 | 163000000000 | 109000000000000 | 0.3922 | 0.2485 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0043 | 0.0007 | 0.0256 | 0.0133 | 0.0488 | 0.0204 | 0.0442 | 0.0136 | 0.0551 | 0.0226 | 0.8197 | 0.9294 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0007 | 0.0151 | 0.0133 | 0.0258 | 0.0204 | 0.0208 | 0.0122 | 0.0270 | 0.0190 | 0.9099 | 0.9344 | 0.0036 | 0.2000 | 0.0145 | 0.8000 | 0.0163 | 0.0000 | 0.0435 | 0.0000 | 0.0870 | 0.0000 | 0.1431 | 0.0000 | 0.0833 | 0.0000 | 0.1105 | 0.0000 | 0.4982 | 0.0000 | 0.0019 | 0.0019 | 0.0061 | 0.0129 | 0.0399 | 0.0633 | 0.0672 | 0.0987 | 0.7081 | 5 | 7 | 8 | 9 | 11 | 13 | 15 | 20 | 32 | 0.2512 | 0.44 | 1.751 | 0.7487 | 564.9 | 50306.4 | 9130000 | 2400000000 | 0.5918 | 0.0979 | 0.0534 | 0.0357 | 0.0820 | 0.0510 | 0.0996 | 0.0522 | 0.1245 | 0.0695 | 0.1572 | 0.0948 | 0.1789 | 0.1024 | 0.1727 | 0.1371 | 0.1011 | 0.1779 | 0.0306 | 0.2793 | 0.0244 | 0.0248 | 0.0307 | 0.0322 | 0.0359 | 0.0315 | 0.0432 | 0.0424 | 0.0663 | 0.0619 | 0.0788 | 0.0696 | 0.0772 | 0.0803 | 0.1043 | 0.1080 | 0.5391 | 0.5493 | 0.0219 | 0.0129 | 0.0172 | 0.0233 | 0.0256 | 0.0259 | 0.0339 | 0.0291 | 0.0516 | 0.0505 | 0.0793 | 0.0627 | 0.0652 | 0.0524 | 0.0814 | 0.0996 | 0.6239 | 0.6436 | 0.0286 | 0.0414 | 0.0352 | 0.0447 | 0.0521 | 0.0660 | 0.0663 | 0.1015 | 0.5642 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 919 | 347 | | 5602 | 6122 | 469.4 | 79.21 | 27.49 | 47.62 | 357 | 396 | 427 | 455 | 479 | 496 | 513 | 531 | 559 | 0.1042 | 638 | 0.998 | 133.18 | 37.86 | 1 | 0.0605 | 339 | 0.0017 | 16.11 | 6.642 | 0.3084 | 226643.0 | 112000000 | 57000000000 | 29500000000000 | 0.4201 | 0.2305 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0000 | 0.0068 | 0.0007 | 0.0224 | 0.0104 | 0.0352 | 0.0294 | 0.0373 | 0.0137 | 0.0623 | 0.0225 | 0.8308 | 0.9233 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0025 | 0.0000 | 0.0042 | 0.0005 | 0.0136 | 0.0097 | 0.0247 | 0.0272 | 0.0207 | 0.0098 | 0.0262 | 0.0177 | 0.9067 | 0.9351 | 0.0187 | 0.0000 | 0.0093 | 0.0541 | 0.0093 | 0.0811 | 0.0318 | 0.1622 | 0.0486 | 0.1892 | 0.0542 | 0.1892 | 0.0710 | 0.0811 | 0.0841 | 0.1351 | 0.6729 | 0.1081 | 0.0000 | 0.0020 | 0.0049 | 0.0120 | 0.0273 | 0.0462 | 0.0524 | 0.0908 | 0.7645 | 8 | 10 | 12 | 14 | 15 | 17 | 20 | 29 | 50 | 0.3237 | 1.45 | 2.056 | 0.8309 | 3023.4 | 1020000 | 532000000 | 337000000000 | 0.5358 | 0.1270 | 0.0965 | 0.0392 | 0.0856 | 0.0530 | 0.0911 | 0.0723 | 0.1111 | 0.0933 | 0.1840 | 0.1154 | 0.1858 | 0.1198 | 0.1056 | 0.1375 | 0.1093 | 0.1452 | 0.0310 | 0.2242 | 0.0300 | 0.0239 | 0.0257 | 0.0316 | 0.0178 | 0.0421 | 0.0165 | 0.0541 | 0.0484 | 0.0733 | 0.0772 | 0.0824 | 0.0502 | 0.0798 | 0.0876 | 0.0900 | 0.6467 | 0.5229 | 0.0018 | 0.0011 | 0.0092 | 0.0063 | 0.0111 | 0.0138 | 0.0129 | 0.0180 | 0.0563 | 0.0624 | 0.0969 | 0.0963 | 0.0572 | 0.0709 | 0.0895 | 0.1270 | 0.6651 | 0.6042 | 0.0092 | 0.0077 | 0.0061 | 0.0146 | 0.0452 | 0.0958 | 0.0598 | 0.0782 | 0.6835 | ||
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 980 | 154 | | 9107 | 15265 | 478.7 | 85.92 | 198.56 | 276.33 | 358 | 401 | 437 | 463 | 485 | 506 | 527 | 552 | 588 | 0.0735 | 1122 | 0.982 | 84.40 | 29.43 | 4 | 0.0254 | 231 | 0.0010 | 22.23 | 7.221 | 0.2396 | 236580.0 | 120000000 | 62600000000 | 33300000000000 | 0.4434 | 0.2060 | 0.0008 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0001 | 0.0113 | 0.0006 | 0.0270 | 0.0119 | 0.0415 | 0.0194 | 0.0463 | 0.0139 | 0.0694 | 0.0222 | 0.7980 | 0.9319 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0012 | 0.0000 | 0.0040 | 0.0006 | 0.0131 | 0.0117 | 0.0209 | 0.0179 | 0.0208 | 0.0114 | 0.0297 | 0.0180 | 0.9101 | 0.9405 | 0.0083 | 0.0294 | 0.0173 | 0.0588 | 0.0273 | 0.0882 | 0.0380 | 0.2059 | 0.0512 | 0.2353 | 0.0760 | 0.1471 | 0.0950 | 0.1471 | 0.1230 | 0.0588 | 0.5640 | 0.0294 | 0.0010 | 0.0031 | 0.0072 | 0.0149 | 0.0256 | 0.0345 | 0.0450 | 0.0565 | 0.8122 | 11 | 14 | 19 | 34 | 73 | 133 | 224 | 349 | 565 | 0.0491 | 47.73 | 5.568 | 0.4783 | 115779.0 | 101000000 | 112000000000 | 147000000000000 | 0.3844 | 0.2395 | 0.0410 | 0.0015 | 0.1640 | 0.0173 | 0.2243 | 0.0857 | 0.1640 | 0.1357 | 0.1446 | 0.1765 | 0.1106 | 0.1922 | 0.0789 | 0.1361 | 0.0472 | 0.1023 | 0.0255 | 0.1526 | 0.0004 | 0.0003 | 0.0011 | 0.0014 | 0.0023 | 0.0048 | 0.0151 | 0.0114 | 0.0519 | 0.0457 | 0.0774 | 0.0628 | 0.0614 | 0.0517 | 0.0854 | 0.0750 | 0.7052 | 0.7469 | 0.0002 | 0.0005 | 0.0018 | 0.0031 | 0.0067 | 0.0089 | 0.0220 | 0.0270 | 0.0687 | 0.0786 | 0.1061 | 0.1226 | 0.0859 | 0.0881 | 0.1079 | 0.1098 | 0.6006 | 0.5613 | 0.0004 | 0.0012 | 0.0052 | 0.0181 | 0.0596 | 0.0890 | 0.0721 | 0.1031 | 0.6512 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 141 | 699 | | 7154 | 15239 | 575.9 | 95.31 | 29.74 | 48.68 | 449 | 502 | 533 | 558 | 579 | 601 | 622 | 652 | 696 | 0.0671 | 1023 | 0.931 | 90.61 | 28.60 | 3 | 0.0352 | 252 | 0.0011 | 31.86 | 7.150 | 0.2308 | 340741.0 | 207000000 | 128000000000 | 80800000000000 | 0.4150 | 0.2161 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0061 | 0.0006 | 0.0245 | 0.0127 | 0.0495 | 0.0227 | 0.0463 | 0.0142 | 0.0702 | 0.0222 | 0.8014 | 0.9276 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0025 | 0.0003 | 0.0155 | 0.0122 | 0.0287 | 0.0212 | 0.0234 | 0.0112 | 0.0340 | 0.0164 | 0.8955 | 0.9387 | 0.0066 | 0.0313 | 0.0131 | 0.1875 | 0.0210 | 0.0938 | 0.0329 | 0.1250 | 0.0631 | 0.1875 | 0.0972 | 0.1250 | 0.0907 | 0.0938 | 0.1196 | 0.1250 | 0.5558 | 0.0313 | 0.0011 | 0.0046 | 0.0060 | 0.0179 | 0.0447 | 0.0660 | 0.0690 | 0.0842 | 0.7066 | 6 | 8 | 9 | 10 | 12 | 15 | 21 | 33 | 71 | 0.1972 | 1.48 | 2.529 | 0.7147 | 3254.2 | 656547 | 165000000 | 46700000000 | 0.5056 | 0.1413 | 0.0414 | 0.0294 | 0.0670 | 0.0284 | 0.1535 | 0.0479 | 0.1859 | 0.0812 | 0.1934 | 0.1171 | 0.1618 | 0.1309 | 0.1106 | 0.1486 | 0.0640 | 0.2072 | 0.0226 | 0.2093 | 0.0062 | 0.0147 | 0.0081 | 0.0103 | 0.0180 | 0.0156 | 0.0240 | 0.0182 | 0.0531 | 0.0425 | 0.0837 | 0.0718 | 0.0721 | 0.0609 | 0.0963 | 0.1079 | 0.6385 | 0.6580 | 0.0031 | 0.0036 | 0.0076 | 0.0056 | 0.0132 | 0.0156 | 0.0287 | 0.0324 | 0.0651 | 0.0720 | 0.0970 | 0.0980 | 0.0707 | 0.0720 | 0.1050 | 0.1032 | 0.6096 | 0.5974 | 0.0052 | 0.0084 | 0.0102 | 0.0335 | 0.0664 | 0.0836 | 0.0740 | 0.0976 | 0.6210 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 561 | 247 | | 4445 | 15033 | 466.1 | 65.09 | 63.62 | 138.06 | 379 | 413 | 433 | 450 | 466 | 481 | 499 | 521 | 551 | 0.0559 | 840 | 1.186 | 46.40 | 17.49 | 1 | 0.0270 | 120 | 0.0015 | 34.76 | 6.820 | 0.2169 | 221513.0 | 107000000 | 52800000000 | 26400000000000 | 0.4116 | 0.2311 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0035 | 0.0002 | 0.0355 | 0.0137 | 0.0646 | 0.0248 | 0.0635 | 0.0142 | 0.0910 | 0.0205 | 0.7407 | 0.9266 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0002 | 0.0221 | 0.0137 | 0.0368 | 0.0248 | 0.0314 | 0.0142 | 0.0456 | 0.0187 | 0.8620 | 0.9284 | 0.0110 | 1.0000 | 0.0192 | 0.0000 | 0.0219 | 0.0000 | 0.0959 | 0.0000 | 0.1479 | 0.0000 | 0.1726 | 0.0000 | 0.1397 | 0.0000 | 0.1288 | 0.0000 | 0.2630 | 0.0000 | 0.0004 | 0.0036 | 0.0085 | 0.0278 | 0.0732 | 0.0996 | 0.0961 | 0.1302 | 0.5606 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 57 | 200 | 0.2619 | 11.61 | 3.053 | 0.7574 | 23105.5 | 14100000 | 11000000000 | 10100000000000 | 0.4691 | 0.1844 | 0.0363 | 0.0081 | 0.0726 | 0.0208 | 0.0726 | 0.0728 | 0.1501 | 0.0786 | 0.1622 | 0.1110 | 0.1671 | 0.1260 | 0.1574 | 0.1191 | 0.1090 | 0.1445 | 0.0726 | 0.3191 | 0.0003 | 0.0012 | 0.0013 | 0.0030 | 0.0023 | 0.0044 | 0.0077 | 0.0094 | 0.0229 | 0.0195 | 0.0265 | 0.0301 | 0.0245 | 0.0248 | 0.0368 | 0.0387 | 0.8777 | 0.8689 | 0.0011 | 0.0000 | 0.0011 | 0.0004 | 0.0022 | 0.0024 | 0.0108 | 0.0091 | 0.0238 | 0.0234 | 0.0309 | 0.0313 | 0.0313 | 0.0317 | 0.0395 | 0.0527 | 0.8593 | 0.8490 | 0.0003 | 0.0007 | 0.0048 | 0.0104 | 0.0214 | 0.0308 | 0.0235 | 0.0443 | 0.8637 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 292 | 776 | | 6777 | 12524 | 325.6 | 51.91 | 172.85 | 222.30 | 258 | 277 | 296 | 311 | 323 | 337 | 352 | 369 | 393 | 0.0787 | 986 | 1.019 | 135.34 | 41.01 | 1 | 0.0484 | 328 | 0.0017 | 16.93 | 6.629 | 0.2646 | 108700.0 | 37200000 | 13000000000 | 4670000000000 | 0.3905 | 0.2545 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0001 | 0.0131 | 0.0003 | 0.0300 | 0.0124 | 0.0571 | 0.0234 | 0.0742 | 0.0142 | 0.0991 | 0.0285 | 0.7210 | 0.9211 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0000 | 0.0071 | 0.0001 | 0.0167 | 0.0114 | 0.0295 | 0.0193 | 0.0326 | 0.0106 | 0.0443 | 0.0171 | 0.8660 | 0.9414 | 0.0057 | 0.0000 | 0.0114 | 0.0000 | 0.0341 | 0.0000 | 0.0994 | 0.0000 | 0.0994 | 0.0000 | 0.1605 | 0.0000 | 0.1179 | 0.0000 | 0.1264 | 0.0000 | 0.3452 | 0.0000 | 0.0015 | 0.0034 | 0.0073 | 0.0208 | 0.0531 | 0.0784 | 0.0815 | 0.1227 | 0.6313 | 14 | 16 | 19 | 25 | 51 | 113 | 215 | 343 | 515 | 0.0450 | 24.78 | 5.251 | 0.4914 | 79286.9 | 49200000 | 36500000000 | 31300000000000 | 0.4891 | 0.1521 | 0.0682 | 0.0006 | 0.2302 | 0.0144 | 0.3264 | 0.1428 | 0.1949 | 0.1888 | 0.1084 | 0.2199 | 0.0560 | 0.1929 | 0.0097 | 0.1180 | 0.0049 | 0.0760 | 0.0012 | 0.0466 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0015 | 0.0099 | 0.0101 | 0.0578 | 0.0482 | 0.0893 | 0.0778 | 0.0562 | 0.0523 | 0.0885 | 0.0782 | 0.6971 | 0.7317 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0023 | 0.0032 | 0.0138 | 0.0193 | 0.0706 | 0.0776 | 0.1115 | 0.1144 | 0.0701 | 0.0761 | 0.0996 | 0.1129 | 0.6310 | 0.5957 | 0.0000 | 0.0000 | 0.0012 | 0.0129 | 0.0628 | 0.1014 | 0.0584 | 0.0960 | 0.6673 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 977 | 894 | | 8678 | 22119 | 392.0 | 75.13 | 173.89 | 314.23 | 282 | 322 | 354 | 381 | 401 | 420 | 435 | 453 | 485 | 0.0511 | 1131 | 1.201 | 88.96 | 38.42 | 7 | 0.0282 | 245 | 0.0021 | 9.63 | 6.499 | 0.3468 | 159312.0 | 66800000 | 28800000000 | 12700000000000 | 0.4083 | 0.2246 | 0.0002 | 0.0000 | 0.0025 | 0.0000 | 0.0025 | 0.0001 | 0.0084 | 0.0015 | 0.0256 | 0.0120 | 0.0520 | 0.0300 | 0.0441 | 0.0144 | 0.0689 | 0.0254 | 0.7959 | 0.9166 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0007 | 0.0001 | 0.0032 | 0.0014 | 0.0140 | 0.0107 | 0.0286 | 0.0280 | 0.0184 | 0.0113 | 0.0282 | 0.0210 | 0.9063 | 0.9274 | 0.0066 | 0.0000 | 0.0148 | 0.0000 | 0.0206 | 0.0000 | 0.0378 | 0.0000 | 0.0395 | 0.0000 | 0.0625 | 0.0000 | 0.0740 | 0.0000 | 0.0806 | 0.0000 | 0.6637 | 0.0000 | 0.0015 | 0.0023 | 0.0048 | 0.0094 | 0.0270 | 0.0347 | 0.0425 | 0.0628 | 0.8151 | 8 | 9 | 11 | 13 | 17 | 36 | 101 | 281 | 635 | 0.1573 | 22.71 | 4.082 | 0.6152 | 128970.0 | 132000000 | 157000000000 | 209000000000000 | 0.4818 | 0.1310 | 0.0786 | 0.0027 | 0.1743 | 0.0342 | 0.2141 | 0.1218 | 0.1446 | 0.1207 | 0.1503 | 0.1613 | 0.1230 | 0.1795 | 0.0501 | 0.1111 | 0.0353 | 0.1058 | 0.0296 | 0.1629 | 0.0005 | 0.0002 | 0.0003 | 0.0003 | 0.0018 | 0.0015 | 0.0102 | 0.0083 | 0.0355 | 0.0349 | 0.0697 | 0.0563 | 0.0468 | 0.0443 | 0.0615 | 0.0621 | 0.7736 | 0.7921 | 0.0002 | 0.0008 | 0.0014 | 0.0008 | 0.0024 | 0.0030 | 0.0102 | 0.0095 | 0.0454 | 0.0447 | 0.0733 | 0.0818 | 0.0542 | 0.0653 | 0.0806 | 0.0799 | 0.7323 | 0.7140 | 0.0002 | 0.0013 | 0.0044 | 0.0091 | 0.0417 | 0.0714 | 0.0488 | 0.0701 | 0.7531 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 740 | 703 | | 8862 | 18824 | 530.1 | 80.43 | 114.15 | 251.56 | 421 | 467 | 496 | 517 | 535 | 553 | 573 | 598 | 631 | 0.0548 | 1032 | 0.545 | 114.22 | 22.67 | 5 | 0.0372 | 330 | 0.0009 | 38.41 | 7.314 | 0.2073 | 287452.0 | 159000000 | 89500000000 | 51200000000000 | 0.4491 | 0.2025 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0007 | 0.0001 | 0.0056 | 0.0007 | 0.0282 | 0.0139 | 0.0564 | 0.0200 | 0.0512 | 0.0144 | 0.0715 | 0.0211 | 0.7858 | 0.9298 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0016 | 0.0007 | 0.0179 | 0.0139 | 0.0306 | 0.0200 | 0.0252 | 0.0144 | 0.0335 | 0.0202 | 0.8913 | 0.9307 | 0.0075 | 1.0000 | 0.0188 | 0.0000 | 0.0225 | 0.0000 | 0.0476 | 0.0000 | 0.1164 | 0.0000 | 0.1640 | 0.0000 | 0.1014 | 0.0000 | 0.1502 | 0.0000 | 0.3717 | 0.0000 | 0.0006 | 0.0036 | 0.0074 | 0.0181 | 0.0434 | 0.0613 | 0.0734 | 0.0863 | 0.7059 | 9 | 10 | 12 | 13 | 15 | 20 | 38 | 121 | 352 | 0.1429 | 9.00 | 3.049 | 0.5952 | 76308.2 | 79500000 | 99600000000 | 139000000000000 | 0.5235 | 0.1294 | 0.0259 | 0.0023 | 0.0761 | 0.0164 | 0.2120 | 0.0561 | 0.1942 | 0.0865 | 0.2006 | 0.1645 | 0.1003 | 0.2050 | 0.1036 | 0.1458 | 0.0631 | 0.1341 | 0.0243 | 0.1894 | 0.0000 | 0.0004 | 0.0002 | 0.0004 | 0.0012 | 0.0011 | 0.0067 | 0.0072 | 0.0396 | 0.0383 | 0.0538 | 0.0475 | 0.0401 | 0.0385 | 0.0569 | 0.0591 | 0.8015 | 0.8073 | 0.0003 | 0.0000 | 0.0006 | 0.0006 | 0.0017 | 0.0021 | 0.0056 | 0.0079 | 0.0476 | 0.0539 | 0.0673 | 0.0667 | 0.0437 | 0.0521 | 0.0707 | 0.0758 | 0.7625 | 0.7409 | 0.0000 | 0.0005 | 0.0016 | 0.0065 | 0.0428 | 0.0586 | 0.0418 | 0.0664 | 0.7819 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 422 | 387 | | 8367 | 21686 | 338.6 | 51.23 | 216.62 | 253.93 | 275 | 292 | 307 | 321 | 337 | 351 | 367 | 383 | 406 | 0.0592 | 1284 | 1.224 | 118.07 | 44.69 | 1 | 0.0354 | 296 | 0.0016 | 21.25 | 6.715 | 0.2518 | 117279.0 | 41500000 | 15000000000 | 5540000000000 | 0.4429 | 0.2078 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0080 | 0.0001 | 0.0305 | 0.0112 | 0.0543 | 0.0192 | 0.0664 | 0.0146 | 0.1150 | 0.0208 | 0.7238 | 0.9341 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0034 | 0.0000 | 0.0155 | 0.0105 | 0.0264 | 0.0169 | 0.0305 | 0.0096 | 0.0535 | 0.0147 | 0.8698 | 0.9484 | 0.0147 | 0.0000 | 0.0209 | 0.0000 | 0.0466 | 0.0000 | 0.0798 | 0.0000 | 0.1325 | 0.0000 | 0.1509 | 0.0000 | 0.1166 | 0.0000 | 0.1387 | 0.0000 | 0.2994 | 0.0000 | 0.0029 | 0.0037 | 0.0079 | 0.0179 | 0.0489 | 0.0872 | 0.0769 | 0.1138 | 0.6407 | 23 | 31 | 44 | 65 | 97 | 158 | 256 | 389 | 599 | 0.0168 | 30.30 | 6.006 | 0.4494 | 111401.0 | 80200000 | 68700000000 | 66100000000000 | 0.5043 | 0.1472 | 0.0237 | 0.0026 | 0.1369 | 0.0072 | 0.2565 | 0.0574 | 0.1751 | 0.1186 | 0.1568 | 0.1945 | 0.1196 | 0.2092 | 0.0501 | 0.1261 | 0.0356 | 0.1132 | 0.0458 | 0.1711 | 0.0002 | 0.0003 | 0.0005 | 0.0006 | 0.0022 | 0.0014 | 0.0105 | 0.0091 | 0.0514 | 0.0447 | 0.0911 | 0.0790 | 0.0565 | 0.0498 | 0.0825 | 0.0754 | 0.7050 | 0.7396 | 0.0003 | 0.0002 | 0.0011 | 0.0016 | 0.0023 | 0.0053 | 0.0156 | 0.0192 | 0.0627 | 0.0685 | 0.1061 | 0.1174 | 0.0749 | 0.0819 | 0.0955 | 0.0997 | 0.6414 | 0.6062 | 0.0001 | 0.0003 | 0.0026 | 0.0142 | 0.0598 | 0.0932 | 0.0668 | 0.0874 | 0.6756 |