High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 619 | 317 | 7410 | 29983 | 364.7 | 86.29 | 152.06 | 265.97 | 260 | 289 | 313 | 336 | 358 | 380 | 405 | 434 | 477 | 0.0351 | 1051 | 1.206 | 108.37 | 43.84 | 1 | 0.0379 | 281 | 0.0006 | 87.06 | 7.645 | 0.1436 | 140416.0 | 57000000 | 24300000000 | 10900000000000 | 0.4464 | 0.2073 | 0.0005 | 0.0000 | 0.0018 | 0.0001 | 0.0086 | 0.0001 | 0.0271 | 0.0018 | 0.0873 | 0.0187 | 0.1534 | 0.0482 | 0.1532 | 0.0439 | 0.1846 | 0.0654 | 0.3836 | 0.8218 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0001 | 0.0081 | 0.0003 | 0.0365 | 0.0110 | 0.0711 | 0.0286 | 0.0684 | 0.0204 | 0.0949 | 0.0311 | 0.7198 | 0.9085 | 0.0050 | 0.0092 | 0.0093 | 0.0297 | 0.0328 | 0.0343 | 0.0734 | 0.0847 | 0.1290 | 0.1533 | 0.1917 | 0.2197 | 0.1226 | 0.1327 | 0.1347 | 0.1373 | 0.3015 | 0.1991 | 0.0006 | 0.0026 | 0.0110 | 0.0266 | 0.0747 | 0.1389 | 0.1155 | 0.1259 | 0.5043 | 7 | 9 | 11 | 13 | 20 | 43 | 110 | 258 | 517 | 0.1512 | 39.36 | 4.482 | 0.5817 | 93855.6 | 84800000 | 94200000000 | 120000000000000 | 0.4152 | 0.1980 | 0.0734 | 0.0021 | 0.2052 | 0.0259 | 0.2539 | 0.1687 | 0.1640 | 0.1542 | 0.1373 | 0.1932 | 0.0879 | 0.1763 | 0.0480 | 0.1107 | 0.0165 | 0.0824 | 0.0137 | 0.0866 | 0.0000 | 0.0002 | 0.0007 | 0.0005 | 0.0021 | 0.0003 | 0.0100 | 0.0059 | 0.0491 | 0.0469 | 0.0856 | 0.0756 | 0.0537 | 0.0477 | 0.0753 | 0.0702 | 0.7236 | 0.7526 | 0.0003 | 0.0001 | 0.0018 | 0.0006 | 0.0017 | 0.0025 | 0.0090 | 0.0096 | 0.0589 | 0.0634 | 0.0991 | 0.1035 | 0.0632 | 0.0706 | 0.0877 | 0.0978 | 0.6783 | 0.6519 | 0.0001 | 0.0011 | 0.0020 | 0.0119 | 0.0542 | 0.0904 | 0.0605 | 0.0819 | 0.6977 | |
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1271 | 351 | 4157 | 9898 | 475.9 | 89.44 | 163.26 | 251.77 | 360 | 394 | 423 | 449 | 475 | 498 | 524 | 554 | 594 | 0.0813 | 805 | 1.028 | 152.20 | 40.79 | 2 | 0.0871 | 362 | 0.0008 | 73.60 | 7.318 | 0.1483 | 234454.0 | 119000000 | 62600000000 | 33700000000000 | 0.4174 | 0.2233 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0017 | 0.0000 | 0.0196 | 0.0010 | 0.0716 | 0.0187 | 0.1191 | 0.0382 | 0.1160 | 0.0296 | 0.1725 | 0.0500 | 0.4981 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0069 | 0.0007 | 0.0343 | 0.0162 | 0.0480 | 0.0300 | 0.0474 | 0.0157 | 0.0809 | 0.0288 | 0.7811 | 0.9086 | 0.0000 | 0.0390 | 0.0204 | 0.0260 | 0.0471 | 0.1429 | 0.0973 | 0.2597 | 0.1476 | 0.2338 | 0.2057 | 0.1558 | 0.1350 | 0.0779 | 0.1162 | 0.0519 | 0.2308 | 0.0130 | 0.0010 | 0.0010 | 0.0048 | 0.0299 | 0.0676 | 0.1356 | 0.1236 | 0.1472 | 0.4894 | 7 | 10 | 13 | 22 | 39 | 75 | 136 | 293 | 547 | 0.0676 | 32.18 | 4.895 | 0.5343 | 90034.8 | 69000000 | 62100000000 | 62700000000000 | 0.5861 | 0.0893 | 0.0409 | 0.0025 | 0.1595 | 0.0187 | 0.2704 | 0.0934 | 0.2179 | 0.1214 | 0.1595 | 0.1766 | 0.0914 | 0.2054 | 0.0311 | 0.1350 | 0.0214 | 0.1180 | 0.0078 | 0.1290 | 0.0003 | 0.0003 | 0.0013 | 0.0017 | 0.0043 | 0.0049 | 0.0140 | 0.0129 | 0.0478 | 0.0466 | 0.0870 | 0.0765 | 0.0558 | 0.0552 | 0.0797 | 0.0797 | 0.7096 | 0.7222 | 0.0004 | 0.0000 | 0.0016 | 0.0017 | 0.0028 | 0.0043 | 0.0172 | 0.0170 | 0.0537 | 0.0679 | 0.1034 | 0.0909 | 0.0577 | 0.0635 | 0.0885 | 0.0905 | 0.6747 | 0.6642 | 0.0000 | 0.0026 | 0.0026 | 0.0125 | 0.0521 | 0.0922 | 0.0558 | 0.0845 | 0.6978 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 764 | 823 | 6160 | 9088 | 204.9 | 44.54 | 210.61 | 171.66 | 152 | 168 | 179 | 190 | 200 | 211 | 223 | 239 | 264 | 0.0980 | 891 | 1.013 | 96.21 | 25.02 | 1 | 0.0381 | 235 | 0.0012 | 43.96 | 7.040 | 0.1905 | 43952.7 | 9880000 | 2330000000 | 576000000000 | 0.4516 | 0.2009 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0159 | 0.0009 | 0.0737 | 0.0187 | 0.1409 | 0.0415 | 0.1416 | 0.0468 | 0.1792 | 0.0731 | 0.4452 | 0.8191 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0049 | 0.0002 | 0.0318 | 0.0125 | 0.0631 | 0.0233 | 0.0618 | 0.0189 | 0.0953 | 0.0339 | 0.7420 | 0.9113 | 0.0039 | 0.0160 | 0.0106 | 0.0543 | 0.0299 | 0.0607 | 0.0781 | 0.1182 | 0.1408 | 0.1725 | 0.2064 | 0.2013 | 0.1225 | 0.1182 | 0.1524 | 0.1054 | 0.2555 | 0.1534 | 0.0025 | 0.0032 | 0.0104 | 0.0365 | 0.0879 | 0.1397 | 0.1065 | 0.1415 | 0.4718 | 39 | 68 | 97 | 128 | 165 | 210 | 263 | 332 | 440 | 0.0016 | 92.09 | 7.254 | 0.2167 | 73819.8 | 36000000 | 22600000000 | 17500000000000 | 0.5552 | 0.1172 | 0.0288 | 0.0009 | 0.1403 | 0.0040 | 0.2442 | 0.0581 | 0.1735 | 0.1210 | 0.1653 | 0.1922 | 0.1083 | 0.2065 | 0.0802 | 0.1390 | 0.0401 | 0.1287 | 0.0194 | 0.1496 | 0.0002 | 0.0002 | 0.0018 | 0.0009 | 0.0043 | 0.0038 | 0.0235 | 0.0144 | 0.0801 | 0.0642 | 0.1300 | 0.1163 | 0.1023 | 0.0810 | 0.1381 | 0.1164 | 0.5198 | 0.6028 | 0.0014 | 0.0031 | 0.0038 | 0.0031 | 0.0153 | 0.0206 | 0.0400 | 0.0601 | 0.1247 | 0.1250 | 0.1626 | 0.1737 | 0.1107 | 0.1123 | 0.1393 | 0.1368 | 0.4022 | 0.3654 | 0.0003 | 0.0006 | 0.0075 | 0.0304 | 0.1033 | 0.1536 | 0.1133 | 0.1467 | 0.4445 | |
SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 837 | 568 | 3810 | 7691 | 452.3 | 131.47 | 221.21 | 376.57 | 230 | 356 | 426 | 457 | 480 | 503 | 528 | 553 | 586 | 0.0787 | 605 | 1.031 | 95.27 | 22.00 | 2 | 0.0559 | 213 | 0.0026 | 14.07 | 6.352 | 0.2995 | 221894.0 | 114000000 | 60800000000 | 33200000000000 | 0.3620 | 0.2645 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0029 | 0.0000 | 0.0119 | 0.0016 | 0.0530 | 0.0188 | 0.0759 | 0.0350 | 0.0740 | 0.0220 | 0.1050 | 0.0373 | 0.6765 | 0.8854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0145 | 0.0142 | 0.0290 | 0.0275 | 0.0145 | 0.0133 | 0.0244 | 0.0245 | 0.9162 | 0.9198 | 0.0021 | 0.0000 | 0.0054 | 0.0122 | 0.0171 | 0.0000 | 0.0289 | 0.0427 | 0.0567 | 0.1037 | 0.0739 | 0.0732 | 0.1017 | 0.1220 | 0.1210 | 0.0793 | 0.5931 | 0.5671 | 0.0004 | 0.0017 | 0.0021 | 0.0084 | 0.0261 | 0.0433 | 0.0517 | 0.0685 | 0.7977 | 9 | 14 | 18 | 23 | 32 | 56 | 165 | 387 | 734 | 0.0801 | 36.23 | 4.662 | 0.5714 | 190720.0 | 231000000 | 326000000000 | 505000000000000 | 0.5310 | 0.1283 | 0.0284 | 0.0000 | 0.2074 | 0.0058 | 0.3466 | 0.0902 | 0.1307 | 0.1645 | 0.1392 | 0.2082 | 0.0881 | 0.2475 | 0.0256 | 0.1092 | 0.0227 | 0.0975 | 0.0114 | 0.0771 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0008 | 0.0089 | 0.0041 | 0.0491 | 0.0454 | 0.0930 | 0.0827 | 0.0637 | 0.0458 | 0.0885 | 0.0827 | 0.6963 | 0.7387 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0052 | 0.0017 | 0.0063 | 0.0112 | 0.0645 | 0.0730 | 0.1096 | 0.1162 | 0.0739 | 0.0691 | 0.1070 | 0.1072 | 0.6329 | 0.6199 | 0.0000 | 0.0005 | 0.0029 | 0.0082 | 0.0629 | 0.0936 | 0.0739 | 0.0975 | 0.6606 | |||
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 338 | 385 | 6192 | 19742 | 233.9 | 53.78 | 137.63 | 180.46 | 171 | 188 | 203 | 216 | 228 | 242 | 256 | 273 | 303 | 0.0555 | 1095 | 1.184 | 93.43 | 33.02 | 1 | 0.0363 | 225 | 0.0009 | 46.43 | 7.247 | 0.1652 | 57591.1 | 14900000 | 4100000000 | 1190000000000 | 0.3895 | 0.2646 | 0.0000 | 0.0000 | 0.0018 | 0.0002 | 0.0041 | 0.0002 | 0.0216 | 0.0019 | 0.0685 | 0.0188 | 0.1277 | 0.0445 | 0.1508 | 0.0419 | 0.1815 | 0.0664 | 0.4442 | 0.8263 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0002 | 0.0094 | 0.0011 | 0.0292 | 0.0133 | 0.0619 | 0.0277 | 0.0581 | 0.0198 | 0.0873 | 0.0284 | 0.7507 | 0.9093 | 0.0076 | 0.0147 | 0.0066 | 0.0265 | 0.0199 | 0.0265 | 0.0939 | 0.1088 | 0.1319 | 0.1559 | 0.1717 | 0.1706 | 0.1063 | 0.0971 | 0.1395 | 0.1294 | 0.3226 | 0.2706 | 0.0007 | 0.0025 | 0.0074 | 0.0298 | 0.0895 | 0.1288 | 0.1057 | 0.1541 | 0.4816 | 12 | 14 | 17 | 23 | 43 | 88 | 167 | 264 | 387 | 0.0461 | 28.23 | 5.244 | 0.4903 | 51505.6 | 27300000 | 17700000000 | 13300000000000 | 0.5436 | 0.1197 | 0.0589 | 0.0037 | 0.2135 | 0.0134 | 0.3305 | 0.1158 | 0.1622 | 0.1818 | 0.0910 | 0.2308 | 0.0773 | 0.1922 | 0.0344 | 0.1091 | 0.0245 | 0.0820 | 0.0077 | 0.0712 | 0.0000 | 0.0004 | 0.0004 | 0.0007 | 0.0018 | 0.0016 | 0.0103 | 0.0074 | 0.0488 | 0.0426 | 0.0827 | 0.0744 | 0.0564 | 0.0488 | 0.0887 | 0.0770 | 0.7108 | 0.7471 | 0.0003 | 0.0002 | 0.0010 | 0.0013 | 0.0015 | 0.0013 | 0.0126 | 0.0158 | 0.0614 | 0.0710 | 0.1023 | 0.1142 | 0.0737 | 0.0805 | 0.1031 | 0.1182 | 0.6440 | 0.5975 | 0.0002 | 0.0003 | 0.0017 | 0.0124 | 0.0554 | 0.0907 | 0.0685 | 0.0965 | 0.6744 | |
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 382 | 242 | 12664 | 34586 | 373.4 | 98.30 | 213.98 | 284.63 | 263 | 291 | 313 | 335 | 358 | 382 | 408 | 446 | 511 | 0.0376 | 1299 | 0.766 | 102.08 | 31.62 | 1 | 0.0237 | 300 | 0.0005 | 74.63 | 7.800 | 0.1485 | 149085.0 | 63700000 | 29200000000 | 14200000000000 | 0.4340 | 0.2186 | 0.0003 | 0.0001 | 0.0035 | 0.0000 | 0.0057 | 0.0011 | 0.0212 | 0.0027 | 0.0752 | 0.0188 | 0.1495 | 0.0375 | 0.1557 | 0.0407 | 0.1833 | 0.0594 | 0.4057 | 0.8397 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0071 | 0.0004 | 0.0383 | 0.0102 | 0.0764 | 0.0200 | 0.0727 | 0.0183 | 0.1055 | 0.0299 | 0.6974 | 0.9212 | 0.0052 | 0.0055 | 0.0048 | 0.0036 | 0.0180 | 0.0155 | 0.0557 | 0.0675 | 0.0894 | 0.1150 | 0.1198 | 0.1359 | 0.0802 | 0.1004 | 0.1066 | 0.1305 | 0.5202 | 0.4261 | 0.0011 | 0.0038 | 0.0108 | 0.0345 | 0.0819 | 0.1264 | 0.0936 | 0.1140 | 0.5339 | 10 | 14 | 21 | 42 | 78 | 144 | 249 | 393 | 629 | 0.0536 | 36.30 | 5.670 | 0.4778 | 126798.0 | 105000000 | 105000000000 | 118000000000000 | 0.3874 | 0.2464 | 0.0531 | 0.0011 | 0.1879 | 0.0093 | 0.2767 | 0.0927 | 0.1677 | 0.1537 | 0.1237 | 0.2297 | 0.0869 | 0.1936 | 0.0497 | 0.1194 | 0.0326 | 0.0973 | 0.0216 | 0.1031 | 0.0002 | 0.0002 | 0.0003 | 0.0005 | 0.0015 | 0.0010 | 0.0112 | 0.0071 | 0.0544 | 0.0452 | 0.0794 | 0.0732 | 0.0619 | 0.0524 | 0.0887 | 0.0799 | 0.7024 | 0.7405 | 0.0007 | 0.0001 | 0.0007 | 0.0009 | 0.0015 | 0.0024 | 0.0132 | 0.0185 | 0.0721 | 0.0749 | 0.1034 | 0.1143 | 0.0693 | 0.0766 | 0.1068 | 0.1115 | 0.6324 | 0.6008 | 0.0003 | 0.0004 | 0.0017 | 0.0125 | 0.0632 | 0.0921 | 0.0646 | 0.0980 | 0.6673 | |
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1011 | 503 | 8099 | 27715 | 207.4 | 49.29 | 90.32 | 133.45 | 151 | 164 | 175 | 187 | 199 | 212 | 228 | 248 | 276 | 0.0437 | 1212 | 1.109 | 152.01 | 45.19 | 2 | 0.0436 | 353 | 0.0011 | 36.08 | 7.089 | 0.1990 | 45423.4 | 10500000 | 2560000000 | 657000000000 | 0.4089 | 0.2364 | 0.0004 | 0.0000 | 0.0023 | 0.0001 | 0.0071 | 0.0004 | 0.0235 | 0.0021 | 0.0760 | 0.0188 | 0.1336 | 0.0422 | 0.1525 | 0.0391 | 0.1806 | 0.0611 | 0.4239 | 0.8362 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0001 | 0.0108 | 0.0006 | 0.0290 | 0.0107 | 0.0546 | 0.0216 | 0.0625 | 0.0137 | 0.0784 | 0.0235 | 0.7599 | 0.9297 | 0.0031 | 0.0101 | 0.0081 | 0.0067 | 0.0219 | 0.0236 | 0.0663 | 0.0809 | 0.1006 | 0.1720 | 0.1644 | 0.1585 | 0.1294 | 0.1282 | 0.1413 | 0.1619 | 0.3650 | 0.2580 | 0.0019 | 0.0022 | 0.0111 | 0.0259 | 0.0674 | 0.1078 | 0.1033 | 0.1236 | 0.5567 | 7 | 8 | 10 | 11 | 15 | 35 | 93 | 181 | 284 | 0.1964 | 12.37 | 4.050 | 0.6366 | 25966.7 | 10500000 | 5130000000 | 2920000000000 | 0.4760 | 0.1582 | 0.0839 | 0.0025 | 0.2737 | 0.0194 | 0.3606 | 0.1699 | 0.1380 | 0.2452 | 0.0745 | 0.2308 | 0.0467 | 0.1602 | 0.0182 | 0.0849 | 0.0044 | 0.0541 | 0.0000 | 0.0330 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0003 | 0.0003 | 0.0065 | 0.0072 | 0.0442 | 0.0379 | 0.0776 | 0.0649 | 0.0515 | 0.0468 | 0.0806 | 0.0673 | 0.7388 | 0.7756 | 0.0000 | 0.0001 | 0.0003 | 0.0006 | 0.0004 | 0.0007 | 0.0094 | 0.0113 | 0.0554 | 0.0601 | 0.1006 | 0.1144 | 0.0720 | 0.0756 | 0.1022 | 0.1029 | 0.6597 | 0.6343 | 0.0001 | 0.0000 | 0.0006 | 0.0064 | 0.0501 | 0.0888 | 0.0621 | 0.0936 | 0.6982 | |
Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 798 | 428 | 27432 | 45118 | 211.1 | 59.97 | 98.82 | 173.21 | 140 | 162 | 179 | 194 | 208 | 223 | 239 | 258 | 287 | 0.0427 | 1927 | 0.804 | 104.04 | 21.19 | 1 | 0.0082 | 226 | 0.0007 | 43.54 | 7.545 | 0.1862 | 48158.5 | 11800000 | 3050000000 | 838000000000 | 0.4170 | 0.2298 | 0.0009 | 0.0000 | 0.0014 | 0.0001 | 0.0072 | 0.0005 | 0.0254 | 0.0026 | 0.0661 | 0.0188 | 0.1224 | 0.0410 | 0.1361 | 0.0439 | 0.1737 | 0.0674 | 0.4667 | 0.8259 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0001 | 0.0072 | 0.0009 | 0.0239 | 0.0093 | 0.0448 | 0.0189 | 0.0494 | 0.0177 | 0.0650 | 0.0292 | 0.8061 | 0.9239 | 0.0049 | 0.0049 | 0.0082 | 0.0175 | 0.0196 | 0.0265 | 0.0469 | 0.0746 | 0.0894 | 0.1169 | 0.1266 | 0.1677 | 0.1090 | 0.1102 | 0.1271 | 0.1250 | 0.4683 | 0.3566 | 0.0014 | 0.0023 | 0.0066 | 0.0227 | 0.0535 | 0.0917 | 0.0877 | 0.1135 | 0.6206 | 10 | 12 | 14 | 16 | 20 | 29 | 54 | 137 | 332 | 0.1819 | 23.17 | 3.891 | 0.6587 | 39767.1 | 24100000 | 17400000000 | 14100000000000 | 0.4082 | 0.2647 | 0.1462 | 0.0039 | 0.3078 | 0.0465 | 0.2795 | 0.2378 | 0.1040 | 0.2151 | 0.0818 | 0.2042 | 0.0463 | 0.1441 | 0.0206 | 0.0647 | 0.0093 | 0.0494 | 0.0046 | 0.0343 | 0.0000 | 0.0000 | 0.0009 | 0.0006 | 0.0015 | 0.0011 | 0.0142 | 0.0095 | 0.0704 | 0.0604 | 0.0987 | 0.0930 | 0.0678 | 0.0551 | 0.1104 | 0.0943 | 0.6360 | 0.6860 | 0.0003 | 0.0000 | 0.0017 | 0.0017 | 0.0033 | 0.0043 | 0.0185 | 0.0216 | 0.0848 | 0.0897 | 0.1211 | 0.1251 | 0.0804 | 0.0863 | 0.1188 | 0.1212 | 0.5710 | 0.5502 | 0.0001 | 0.0006 | 0.0030 | 0.0167 | 0.0751 | 0.1185 | 0.0740 | 0.1117 | 0.6002 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 320 | 667 | 5012 | 4003 | 144.6 | 31.00 | 256.96 | 210.61 | 110 | 119 | 126 | 133 | 139 | 146 | 155 | 168 | 187 | 0.1699 | 680 | 1.061 | 130.67 | 36.72 | 1 | 0.0599 | 300 | 0.0023 | 22.41 | 6.404 | 0.2450 | 21873.6 | 3470000 | 577000000 | 101000000000 | 0.4357 | 0.2084 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0059 | 0.0000 | 0.0223 | 0.0013 | 0.0711 | 0.0189 | 0.1355 | 0.0456 | 0.1443 | 0.0439 | 0.1875 | 0.0634 | 0.4320 | 0.8269 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0000 | 0.0083 | 0.0004 | 0.0355 | 0.0130 | 0.0649 | 0.0252 | 0.0675 | 0.0144 | 0.0966 | 0.0244 | 0.7237 | 0.9225 | 0.0073 | 0.0036 | 0.0158 | 0.0144 | 0.0280 | 0.0758 | 0.0767 | 0.1516 | 0.1571 | 0.1913 | 0.1705 | 0.1733 | 0.1255 | 0.1264 | 0.1437 | 0.1155 | 0.2753 | 0.1480 | 0.0038 | 0.0080 | 0.0127 | 0.0363 | 0.0930 | 0.1303 | 0.1085 | 0.1567 | 0.4507 | 33 | 63 | 100 | 155 | 208 | 265 | 333 | 424 | 568 | 0.0020 | 118.54 | 7.148 | 0.2176 | 110371.0 | 60900000 | 39200000000 | 28100000000000 | 0.4840 | 0.1833 | 0.0323 | 0.0038 | 0.1232 | 0.0212 | 0.2097 | 0.0613 | 0.2097 | 0.1272 | 0.1730 | 0.1779 | 0.1510 | 0.2059 | 0.0587 | 0.1476 | 0.0293 | 0.1272 | 0.0132 | 0.1279 | 0.0005 | 0.0000 | 0.0055 | 0.0033 | 0.0099 | 0.0087 | 0.0307 | 0.0229 | 0.0823 | 0.0715 | 0.1368 | 0.1227 | 0.1011 | 0.0932 | 0.1293 | 0.1165 | 0.5040 | 0.5611 | 0.0007 | 0.0055 | 0.0045 | 0.0028 | 0.0112 | 0.0148 | 0.0389 | 0.0572 | 0.1243 | 0.1210 | 0.1534 | 0.1681 | 0.1213 | 0.1385 | 0.1445 | 0.1376 | 0.4012 | 0.3546 | 0.0030 | 0.0066 | 0.0156 | 0.0361 | 0.0968 | 0.1437 | 0.1203 | 0.1371 | 0.4408 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 564 | 834 | 5735 | 9264 | 386.5 | 90.39 | 113.25 | 134.91 | 287 | 312 | 332 | 351 | 371 | 393 | 423 | 457 | 512 | 0.0955 | 885 | 1.153 | 94.87 | 36.50 | 1 | 0.0424 | 243 | 0.0010 | 39.47 | 7.169 | 0.1888 | 157556.0 | 67800000 | 30700000000 | 14700000000000 | 0.4429 | 0.2115 | 0.0008 | 0.0000 | 0.0019 | 0.0006 | 0.0036 | 0.0017 | 0.0202 | 0.0044 | 0.0679 | 0.0189 | 0.1422 | 0.0466 | 0.1486 | 0.0405 | 0.1705 | 0.0615 | 0.4443 | 0.8259 | 0.0004 | 0.0000 | 0.0011 | 0.0002 | 0.0024 | 0.0009 | 0.0105 | 0.0021 | 0.0358 | 0.0126 | 0.0710 | 0.0308 | 0.0693 | 0.0219 | 0.0813 | 0.0324 | 0.7282 | 0.8991 | 0.0076 | 0.0105 | 0.0123 | 0.0026 | 0.0123 | 0.0211 | 0.0550 | 0.0632 | 0.0920 | 0.1395 | 0.1404 | 0.1447 | 0.0920 | 0.1289 | 0.1262 | 0.1421 | 0.4620 | 0.3474 | 0.0012 | 0.0032 | 0.0097 | 0.0385 | 0.0838 | 0.1187 | 0.0956 | 0.1126 | 0.5367 | 9 | 11 | 13 | 22 | 52 | 96 | 147 | 211 | 309 | 0.0380 | 20.61 | 5.347 | 0.4709 | 31025.6 | 11600000 | 5240000000 | 2690000000000 | 0.6389 | 0.0617 | 0.0305 | 0.0023 | 0.1469 | 0.0170 | 0.2362 | 0.0978 | 0.1627 | 0.1213 | 0.1345 | 0.1582 | 0.0949 | 0.1687 | 0.0983 | 0.1201 | 0.0588 | 0.1125 | 0.0373 | 0.2021 | 0.0005 | 0.0000 | 0.0003 | 0.0002 | 0.0016 | 0.0026 | 0.0128 | 0.0086 | 0.0534 | 0.0432 | 0.0826 | 0.0776 | 0.0631 | 0.0491 | 0.1081 | 0.0918 | 0.6777 | 0.7269 | 0.0000 | 0.0008 | 0.0010 | 0.0008 | 0.0054 | 0.0051 | 0.0217 | 0.0249 | 0.0633 | 0.0785 | 0.1178 | 0.1224 | 0.0796 | 0.0890 | 0.1260 | 0.1383 | 0.5852 | 0.5404 | 0.0000 | 0.0006 | 0.0027 | 0.0183 | 0.0601 | 0.0914 | 0.0787 | 0.1213 | 0.6269 | |||
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 707 | 13530 | 19255 | 474.1 | 126.99 | 20.39 | 53.21 | 304 | 394 | 439 | 470 | 494 | 519 | 545 | 573 | 609 | 0.0718 | 1383 | 0.981 | 73.41 | 26.31 | 10 | 0.0152 | 205 | 0.0008 | 44.28 | 7.548 | 0.2080 | 240855.0 | 127000000 | 69400000000 | 38700000000000 | 0.5339 | 0.1308 | 0.0006 | 0.0000 | 0.0010 | 0.0001 | 0.0043 | 0.0006 | 0.0142 | 0.0018 | 0.0585 | 0.0189 | 0.1017 | 0.0371 | 0.0863 | 0.0264 | 0.1091 | 0.0426 | 0.6244 | 0.8725 | 0.0001 | 0.0000 | 0.0002 | 0.0001 | 0.0001 | 0.0000 | 0.0015 | 0.0008 | 0.0170 | 0.0145 | 0.0361 | 0.0292 | 0.0214 | 0.0147 | 0.0347 | 0.0225 | 0.8889 | 0.9183 | 0.0031 | 0.0204 | 0.0058 | 0.0051 | 0.0170 | 0.0636 | 0.0458 | 0.1018 | 0.1021 | 0.1552 | 0.1378 | 0.1578 | 0.1116 | 0.1603 | 0.1412 | 0.1425 | 0.4357 | 0.1934 | 0.0001 | 0.0006 | 0.0021 | 0.0108 | 0.0390 | 0.0782 | 0.0620 | 0.0866 | 0.7204 | 6 | 7 | 8 | 9 | 10 | 11 | 13 | 16 | 31 | 0.4315 | 1.39 | 1.784 | 0.8626 | 3247.0 | 1790000 | 1370000000 | 1200000000000 | 0.6652 | 0.0672 | 0.0808 | 0.0848 | 0.0820 | 0.0869 | 0.1165 | 0.0731 | 0.1440 | 0.0714 | 0.1647 | 0.0831 | 0.1540 | 0.1070 | 0.1277 | 0.1051 | 0.0977 | 0.1288 | 0.0326 | 0.2598 | 0.0277 | 0.0558 | 0.0224 | 0.0571 | 0.0301 | 0.0465 | 0.0388 | 0.0399 | 0.0653 | 0.0505 | 0.0774 | 0.0737 | 0.0629 | 0.0667 | 0.0863 | 0.0911 | 0.5891 | 0.5187 | 0.0078 | 0.0032 | 0.0078 | 0.0050 | 0.0078 | 0.0140 | 0.0168 | 0.0235 | 0.0588 | 0.0587 | 0.0748 | 0.0898 | 0.0643 | 0.0700 | 0.1019 | 0.1020 | 0.6599 | 0.6339 | 0.0183 | 0.0157 | 0.0223 | 0.0265 | 0.0465 | 0.0750 | 0.0550 | 0.0917 | 0.6490 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 849 | 5669 | 11631 | 149.6 | 30.26 | 380.14 | 292.12 | 115 | 126 | 133 | 140 | 146 | 153 | 161 | 172 | 189 | 0.0978 | 1138 | 0.853 | 87.32 | 20.22 | 4 | 0.0376 | 213 | 0.0246 | 2.00 | 4.135 | 0.5882 | 23308.7 | 3780000 | 639000000 | 113000000000 | 0.4512 | 0.2143 | 0.0005 | 0.0000 | 0.0019 | 0.0004 | 0.0066 | 0.0006 | 0.0209 | 0.0047 | 0.0542 | 0.0190 | 0.1074 | 0.0594 | 0.1031 | 0.0456 | 0.1449 | 0.0760 | 0.5605 | 0.7945 | 0.0002 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0005 | 0.0087 | 0.0041 | 0.0281 | 0.0148 | 0.0485 | 0.0422 | 0.0396 | 0.0185 | 0.0686 | 0.0351 | 0.8028 | 0.8846 | 0.0072 | 0.0165 | 0.0217 | 0.0535 | 0.0253 | 0.0535 | 0.0939 | 0.1934 | 0.1721 | 0.2058 | 0.1877 | 0.1934 | 0.1095 | 0.0864 | 0.1300 | 0.0947 | 0.2527 | 0.1029 | 0.0031 | 0.0043 | 0.0152 | 0.0390 | 0.0928 | 0.1383 | 0.1200 | 0.1380 | 0.4493 | 68 | 117 | 173 | 239 | 313 | 389 | 493 | 610 | 797 | 0.0026 | 36.91 | 6.778 | 0.2991 | 229829.0 | 180000000 | 166000000000 | 173000000000000 | 0.5041 | 0.1494 | 0.0174 | 0.0017 | 0.0886 | 0.0073 | 0.1781 | 0.0403 | 0.1658 | 0.0825 | 0.1856 | 0.1556 | 0.1451 | 0.1874 | 0.0933 | 0.1449 | 0.0612 | 0.1473 | 0.0650 | 0.2330 | 0.0002 | 0.0000 | 0.0023 | 0.0006 | 0.0058 | 0.0035 | 0.0167 | 0.0122 | 0.0657 | 0.0480 | 0.1189 | 0.0967 | 0.0796 | 0.0703 | 0.1194 | 0.1013 | 0.5913 | 0.6674 | 0.0015 | 0.0013 | 0.0036 | 0.0039 | 0.0103 | 0.0186 | 0.0328 | 0.0417 | 0.0904 | 0.1037 | 0.1420 | 0.1637 | 0.1030 | 0.1027 | 0.1258 | 0.1376 | 0.4904 | 0.4266 | 0.0006 | 0.0031 | 0.0121 | 0.0249 | 0.0804 | 0.1317 | 0.0936 | 0.1214 | 0.5321 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 503 | 432 | 11808 | 33332 | 318.9 | 77.36 | 142.89 | 210.03 | 224 | 252 | 274 | 294 | 313 | 332 | 354 | 382 | 421 | 0.0347 | 1158 | 1.075 | 96.88 | 32.00 | 1 | 0.0204 | 241 | 0.0011 | 35.28 | 7.136 | 0.2018 | 107664.0 | 38400000 | 14400000000 | 5670000000000 | 0.4385 | 0.2096 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0068 | 0.0004 | 0.0240 | 0.0021 | 0.0823 | 0.0190 | 0.1435 | 0.0483 | 0.1432 | 0.0507 | 0.1608 | 0.0696 | 0.4388 | 0.8100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0071 | 0.0012 | 0.0317 | 0.0115 | 0.0656 | 0.0250 | 0.0600 | 0.0226 | 0.0788 | 0.0331 | 0.7553 | 0.9064 | 0.0047 | 0.0040 | 0.0064 | 0.0162 | 0.0180 | 0.0324 | 0.0588 | 0.1309 | 0.1171 | 0.1646 | 0.1656 | 0.2146 | 0.1257 | 0.1242 | 0.1416 | 0.1026 | 0.3621 | 0.2105 | 0.0020 | 0.0023 | 0.0069 | 0.0236 | 0.0705 | 0.1235 | 0.0941 | 0.1163 | 0.5608 | 6 | 7 | 9 | 11 | 20 | 67 | 166 | 292 | 458 | 0.1413 | 28.98 | 4.701 | 0.5652 | 64528.1 | 40100000 | 31100000000 | 29500000000000 | 0.4198 | 0.2297 | 0.0409 | 0.0008 | 0.1490 | 0.0130 | 0.2877 | 0.0770 | 0.1876 | 0.1317 | 0.1496 | 0.1991 | 0.0863 | 0.2098 | 0.0489 | 0.1278 | 0.0334 | 0.1018 | 0.0167 | 0.1390 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0007 | 0.0046 | 0.0041 | 0.0332 | 0.0264 | 0.0586 | 0.0502 | 0.0443 | 0.0368 | 0.0677 | 0.0562 | 0.7904 | 0.8252 | 0.0000 | 0.0002 | 0.0003 | 0.0008 | 0.0015 | 0.0014 | 0.0069 | 0.0086 | 0.0446 | 0.0485 | 0.0792 | 0.0935 | 0.0610 | 0.0660 | 0.0897 | 0.0966 | 0.7168 | 0.6842 | 0.0000 | 0.0006 | 0.0008 | 0.0069 | 0.0372 | 0.0677 | 0.0539 | 0.0771 | 0.7557 | |
SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 532 | 476 | 5219 | 14862 | 435.3 | 124.40 | 337.57 | 481.74 | 232 | 330 | 406 | 440 | 463 | 485 | 504 | 529 | 568 | 0.0615 | 914 | 1.000 | 128.22 | 48.33 | 2 | 0.0674 | 352 | 0.0008 | 45.97 | 7.490 | 0.1610 | 204925.0 | 101000000 | 51900000000 | 27400000000000 | 0.3800 | 0.2460 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0028 | 0.0002 | 0.0186 | 0.0019 | 0.0502 | 0.0190 | 0.0908 | 0.0389 | 0.0881 | 0.0283 | 0.1132 | 0.0482 | 0.6350 | 0.8635 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0009 | 0.0137 | 0.0123 | 0.0238 | 0.0237 | 0.0137 | 0.0121 | 0.0218 | 0.0185 | 0.9249 | 0.9326 | 0.0043 | 0.0084 | 0.0077 | 0.0422 | 0.0163 | 0.0253 | 0.0463 | 0.0633 | 0.0891 | 0.1266 | 0.1380 | 0.2194 | 0.1157 | 0.1181 | 0.1302 | 0.1646 | 0.4524 | 0.2321 | 0.0000 | 0.0000 | 0.0015 | 0.0080 | 0.0250 | 0.0367 | 0.0598 | 0.0712 | 0.7979 | 11 | 14 | 20 | 38 | 87 | 185 | 377 | 650 | 1059 | 0.0509 | 117.91 | 5.882 | 0.4621 | 346014.0 | 476000000 | 763000000000 | 1.34E+15 | 0.4474 | 0.1983 | 0.0233 | 0.0011 | 0.1329 | 0.0091 | 0.3034 | 0.0582 | 0.1982 | 0.0988 | 0.1639 | 0.2045 | 0.0941 | 0.2654 | 0.0532 | 0.1442 | 0.0199 | 0.1116 | 0.0111 | 0.1073 | 0.0000 | 0.0003 | 0.0002 | 0.0009 | 0.0017 | 0.0007 | 0.0048 | 0.0049 | 0.0457 | 0.0381 | 0.0817 | 0.0764 | 0.0489 | 0.0433 | 0.0740 | 0.0659 | 0.7430 | 0.7695 | 0.0002 | 0.0003 | 0.0007 | 0.0008 | 0.0019 | 0.0033 | 0.0107 | 0.0121 | 0.0534 | 0.0598 | 0.0963 | 0.1052 | 0.0590 | 0.0678 | 0.0919 | 0.0965 | 0.6858 | 0.6543 | 0.0000 | 0.0008 | 0.0017 | 0.0079 | 0.0480 | 0.0926 | 0.0499 | 0.0801 | 0.7189 | |
MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 406 | 806 | 3869 | 9909 | 688.7 | 123.70 | 61.45 | 130.52 | 523 | 588 | 635 | 670 | 698 | 722 | 743 | 770 | 857 | 0.0768 | 761 | 1.128 | 89.45 | 33.12 | 2 | 0.0605 | 234 | 0.0009 | 60.15 | 7.294 | 0.1719 | 489556.0 | 358000000 | 269000000000 | 207000000000000 | 0.3551 | 0.2759 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0039 | 0.0005 | 0.0389 | 0.0191 | 0.0470 | 0.0343 | 0.0473 | 0.0252 | 0.0666 | 0.0433 | 0.7950 | 0.8776 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0021 | 0.0005 | 0.0251 | 0.0187 | 0.0338 | 0.0305 | 0.0311 | 0.0174 | 0.0429 | 0.0274 | 0.8639 | 0.9056 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0217 | 0.0000 | 0.0522 | 0.0000 | 0.0435 | 0.0000 | 0.0783 | 0.0000 | 0.0696 | 0.0000 | 0.7348 | 0.0000 | 0.0005 | 0.0014 | 0.0048 | 0.0144 | 0.0393 | 0.0672 | 0.0561 | 0.0859 | 0.7303 | 6 | 8 | 9 | 10 | 11 | 13 | 21 | 63 | 186 | 0.1948 | 6.58 | 2.831 | 0.6506 | 20808.7 | 11500000 | 7940000000 | 6280000000000 | 0.3866 | 0.2159 | 0.0387 | 0.0072 | 0.1613 | 0.0273 | 0.2355 | 0.1164 | 0.2065 | 0.1193 | 0.1839 | 0.1379 | 0.0903 | 0.1897 | 0.0548 | 0.1149 | 0.0194 | 0.1379 | 0.0097 | 0.1494 | 0.0005 | 0.0000 | 0.0005 | 0.0008 | 0.0009 | 0.0004 | 0.0147 | 0.0132 | 0.0372 | 0.0371 | 0.0689 | 0.0556 | 0.0358 | 0.0342 | 0.0611 | 0.0671 | 0.7804 | 0.7917 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0032 | 0.0017 | 0.0118 | 0.0121 | 0.0428 | 0.0537 | 0.0707 | 0.0779 | 0.0386 | 0.0467 | 0.0739 | 0.0848 | 0.7590 | 0.7213 | 0.0005 | 0.0005 | 0.0020 | 0.0125 | 0.0435 | 0.0659 | 0.0390 | 0.0649 | 0.7712 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1056 | 260 | 4207 | 15495 | 500.5 | 108.07 | 87.49 | 106.42 | 370 | 405 | 433 | 464 | 493 | 520 | 549 | 587 | 643 | 0.0565 | 876 | 0.989 | 119.87 | 30.61 | 1 | 0.0661 | 278 | 0.0007 | 62.59 | 7.399 | 0.1476 | 262186.0 | 144000000 | 82200000000 | 49100000000000 | 0.4288 | 0.2109 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0033 | 0.0003 | 0.0164 | 0.0020 | 0.0574 | 0.0191 | 0.1257 | 0.0417 | 0.1374 | 0.0355 | 0.1640 | 0.0528 | 0.4940 | 0.8486 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0015 | 0.0000 | 0.0073 | 0.0012 | 0.0297 | 0.0144 | 0.0559 | 0.0271 | 0.0612 | 0.0163 | 0.0749 | 0.0302 | 0.7681 | 0.9108 | 0.0029 | 0.0000 | 0.0086 | 0.0052 | 0.0187 | 0.0363 | 0.0691 | 0.0777 | 0.1281 | 0.2280 | 0.1727 | 0.1969 | 0.0964 | 0.0829 | 0.1410 | 0.1451 | 0.3626 | 0.2280 | 0.0015 | 0.0035 | 0.0035 | 0.0266 | 0.0693 | 0.1151 | 0.0925 | 0.1231 | 0.5648 | 8 | 11 | 16 | 26 | 43 | 64 | 98 | 150 | 246 | 0.0352 | 15.63 | 5.119 | 0.5277 | 18978.6 | 5860000 | 2150000000 | 885000000000 | 0.5211 | 0.1359 | 0.0214 | 0.0046 | 0.0878 | 0.0160 | 0.1521 | 0.0567 | 0.1383 | 0.0743 | 0.1784 | 0.1350 | 0.1508 | 0.1607 | 0.1196 | 0.1350 | 0.0920 | 0.1405 | 0.0595 | 0.2771 | 0.0007 | 0.0012 | 0.0020 | 0.0016 | 0.0043 | 0.0040 | 0.0126 | 0.0130 | 0.0415 | 0.0366 | 0.0643 | 0.0582 | 0.0519 | 0.0478 | 0.0821 | 0.0687 | 0.7407 | 0.7690 | 0.0005 | 0.0003 | 0.0002 | 0.0013 | 0.0029 | 0.0039 | 0.0170 | 0.0181 | 0.0503 | 0.0629 | 0.0867 | 0.0982 | 0.0697 | 0.0732 | 0.0965 | 0.1166 | 0.6762 | 0.6256 | 0.0004 | 0.0016 | 0.0036 | 0.0126 | 0.0506 | 0.0725 | 0.0620 | 0.0889 | 0.7079 | |||
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 508 | 133 | 5112 | 15953 | 596.9 | 122.93 | 209.99 | 332.25 | 447 | 490 | 521 | 552 | 585 | 617 | 653 | 698 | 767 | 0.0564 | 899 | 0.855 | 86.15 | 24.76 | 1 | 0.0428 | 219 | 0.0004 | 156.57 | 7.925 | 0.1053 | 371349.0 | 241000000 | 162000000000 | 113000000000000 | 0.4423 | 0.2051 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0187 | 0.0008 | 0.0672 | 0.0192 | 0.1466 | 0.0410 | 0.1398 | 0.0373 | 0.1694 | 0.0551 | 0.4551 | 0.8466 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0089 | 0.0004 | 0.0325 | 0.0132 | 0.0678 | 0.0246 | 0.0610 | 0.0151 | 0.0909 | 0.0305 | 0.7386 | 0.9162 | 0.0023 | 0.0043 | 0.0103 | 0.0043 | 0.0195 | 0.0468 | 0.0736 | 0.1319 | 0.1310 | 0.1872 | 0.2080 | 0.2468 | 0.1023 | 0.0936 | 0.1264 | 0.1106 | 0.3264 | 0.1745 | 0.0008 | 0.0025 | 0.0105 | 0.0257 | 0.0758 | 0.1281 | 0.1049 | 0.1184 | 0.5333 | 8 | 10 | 12 | 14 | 20 | 73 | 208 | 417 | 696 | 0.1770 | 37.47 | 4.561 | 0.5961 | 154477.0 | 156000000 | 189000000000 | 260000000000000 | 0.5567 | 0.1171 | 0.0435 | 0.0017 | 0.1317 | 0.0133 | 0.1719 | 0.0920 | 0.1462 | 0.1123 | 0.1551 | 0.1516 | 0.1272 | 0.1707 | 0.1071 | 0.1244 | 0.0737 | 0.1291 | 0.0435 | 0.2049 | 0.0000 | 0.0003 | 0.0002 | 0.0000 | 0.0013 | 0.0010 | 0.0089 | 0.0045 | 0.0312 | 0.0322 | 0.0618 | 0.0501 | 0.0532 | 0.0353 | 0.0709 | 0.0694 | 0.7724 | 0.8070 | 0.0005 | 0.0002 | 0.0000 | 0.0007 | 0.0023 | 0.0015 | 0.0087 | 0.0100 | 0.0449 | 0.0500 | 0.0795 | 0.0826 | 0.0525 | 0.0585 | 0.0887 | 0.0933 | 0.7230 | 0.7032 | 0.0008 | 0.0015 | 0.0023 | 0.0088 | 0.0390 | 0.0736 | 0.0524 | 0.0793 | 0.7423 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 560 | 270 | 5568 | 18268 | 433.5 | 92.93 | 137.20 | 136.94 | 324 | 352 | 376 | 397 | 422 | 446 | 477 | 510 | 564 | 0.0541 | 989 | 1.182 | 95.60 | 36.50 | 1 | 0.0449 | 250 | 0.0012 | 33.93 | 7.010 | 0.1946 | 196527.0 | 93100000 | 46100000000 | 23700000000000 | 0.4332 | 0.2136 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0020 | 0.0002 | 0.0140 | 0.0011 | 0.0717 | 0.0192 | 0.1259 | 0.0400 | 0.1320 | 0.0390 | 0.1664 | 0.0581 | 0.4877 | 0.8422 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0064 | 0.0000 | 0.0304 | 0.0128 | 0.0556 | 0.0229 | 0.0530 | 0.0152 | 0.0754 | 0.0265 | 0.7781 | 0.9225 | 0.0031 | 0.0070 | 0.0071 | 0.0245 | 0.0224 | 0.0280 | 0.0671 | 0.1294 | 0.1180 | 0.1993 | 0.1699 | 0.2133 | 0.1282 | 0.1084 | 0.1506 | 0.1434 | 0.3337 | 0.1469 | 0.0020 | 0.0016 | 0.0052 | 0.0290 | 0.0708 | 0.1225 | 0.0982 | 0.1301 | 0.5406 | 20 | 35 | 55 | 76 | 97 | 124 | 159 | 209 | 290 | 0.0125 | 11.31 | 5.396 | 0.4946 | 37572.9 | 16400000 | 9620000000 | 6730000000000 | 0.5560 | 0.1152 | 0.0139 | 0.0011 | 0.0448 | 0.0071 | 0.1227 | 0.0245 | 0.1370 | 0.0568 | 0.1652 | 0.1234 | 0.1675 | 0.1608 | 0.1217 | 0.1315 | 0.1118 | 0.1516 | 0.1154 | 0.3433 | 0.0013 | 0.0001 | 0.0016 | 0.0026 | 0.0052 | 0.0039 | 0.0169 | 0.0131 | 0.0498 | 0.0475 | 0.0829 | 0.0732 | 0.0663 | 0.0599 | 0.0861 | 0.0802 | 0.6900 | 0.7194 | 0.0015 | 0.0007 | 0.0029 | 0.0034 | 0.0061 | 0.0079 | 0.0209 | 0.0274 | 0.0672 | 0.0758 | 0.1087 | 0.1185 | 0.0846 | 0.0902 | 0.1045 | 0.1152 | 0.6036 | 0.5609 | 0.0021 | 0.0021 | 0.0044 | 0.0190 | 0.0539 | 0.0970 | 0.0768 | 0.0992 | 0.6453 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 439 | 9462 | 17615 | 66.2 | 18.80 | 11.63 | 7.94 | 45 | 48 | 51 | 57 | 63 | 69 | 76 | 85 | 93 | 0.0582 | 1025 | 0.806 | 93.06 | 26.68 | 0 | 0.0260 | 246 | 0.0396 | 0.80 | 3.627 | 0.7208 | 4738.0 | 364637 | 29900000 | 2590000000 | 0.4090 | 0.2322 | 0.0114 | 0.0009 | 0.0137 | 0.0014 | 0.0190 | 0.0032 | 0.0307 | 0.0089 | 0.0497 | 0.0193 | 0.0678 | 0.0417 | 0.0898 | 0.0415 | 0.1269 | 0.0742 | 0.5909 | 0.8088 | 0.0052 | 0.0000 | 0.0064 | 0.0002 | 0.0081 | 0.0003 | 0.0109 | 0.0024 | 0.0165 | 0.0081 | 0.0215 | 0.0205 | 0.0284 | 0.0132 | 0.0370 | 0.0319 | 0.8659 | 0.9234 | 0.0061 | 0.0140 | 0.0065 | 0.0220 | 0.0105 | 0.0451 | 0.0252 | 0.0762 | 0.0304 | 0.1062 | 0.0527 | 0.1333 | 0.0641 | 0.1283 | 0.0933 | 0.1413 | 0.7112 | 0.3337 | 0.0026 | 0.0049 | 0.0086 | 0.0123 | 0.0283 | 0.0339 | 0.0416 | 0.0706 | 0.7972 | 5 | 6 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 0.2867 | 0.33 | 1.922 | 0.8442 | 198.3 | 4862.52 | 154893 | 5820000 | 0.5138 | 0.1400 | 0.0871 | 0.0128 | 0.1401 | 0.0280 | 0.1505 | 0.0586 | 0.1491 | 0.0912 | 0.1521 | 0.1375 | 0.1294 | 0.1665 | 0.1167 | 0.1770 | 0.0606 | 0.1781 | 0.0146 | 0.1503 | 0.0408 | 0.0059 | 0.0668 | 0.0174 | 0.0671 | 0.0381 | 0.0575 | 0.0614 | 0.0582 | 0.0937 | 0.0540 | 0.1156 | 0.0645 | 0.1142 | 0.0925 | 0.1136 | 0.4986 | 0.4402 | 0.0246 | 0.0157 | 0.0222 | 0.0242 | 0.0309 | 0.0310 | 0.0415 | 0.0336 | 0.0492 | 0.0529 | 0.0632 | 0.0663 | 0.0719 | 0.0777 | 0.1169 | 0.1326 | 0.5796 | 0.5660 | 0.0564 | 0.0389 | 0.0353 | 0.0306 | 0.0484 | 0.0603 | 0.0728 | 0.0984 | 0.5589 | |
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 646 | 630 | 4918 | 16500 | 250.8 | 54.45 | 183.21 | 159.38 | 187 | 204 | 216 | 230 | 243 | 258 | 275 | 294 | 325 | 0.0553 | 912 | 1.082 | 114.59 | 36.69 | 1 | 0.0567 | 279 | 0.0010 | 47.80 | 7.180 | 0.1740 | 65866.1 | 18100000 | 5220000000 | 1580000000000 | 0.3928 | 0.2565 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0047 | 0.0000 | 0.0187 | 0.0019 | 0.0548 | 0.0194 | 0.1246 | 0.0446 | 0.1390 | 0.0381 | 0.1798 | 0.0538 | 0.4774 | 0.8422 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0081 | 0.0010 | 0.0259 | 0.0120 | 0.0548 | 0.0269 | 0.0577 | 0.0141 | 0.0883 | 0.0210 | 0.7634 | 0.9249 | 0.0059 | 0.0039 | 0.0012 | 0.0116 | 0.0190 | 0.0814 | 0.0853 | 0.1357 | 0.1291 | 0.1667 | 0.1623 | 0.1744 | 0.1232 | 0.1202 | 0.1374 | 0.1279 | 0.3365 | 0.1783 | 0.0009 | 0.0023 | 0.0064 | 0.0273 | 0.0792 | 0.1152 | 0.1184 | 0.1211 | 0.5291 | 18 | 33 | 60 | 103 | 150 | 198 | 247 | 309 | 400 | 0.0089 | 24.20 | 6.264 | 0.3693 | 58965.6 | 24900000 | 12800000000 | 7660000000000 | 0.5028 | 0.1524 | 0.0298 | 0.0012 | 0.1446 | 0.0060 | 0.2626 | 0.0670 | 0.1569 | 0.1200 | 0.1430 | 0.1772 | 0.1184 | 0.1974 | 0.0763 | 0.1242 | 0.0453 | 0.1282 | 0.0230 | 0.1788 | 0.0001 | 0.0000 | 0.0006 | 0.0004 | 0.0025 | 0.0008 | 0.0117 | 0.0094 | 0.0594 | 0.0454 | 0.1105 | 0.0804 | 0.0780 | 0.0631 | 0.1181 | 0.0977 | 0.6190 | 0.7028 | 0.0007 | 0.0013 | 0.0026 | 0.0028 | 0.0058 | 0.0118 | 0.0286 | 0.0350 | 0.0883 | 0.1071 | 0.1510 | 0.1803 | 0.1152 | 0.1150 | 0.1405 | 0.1436 | 0.4674 | 0.4032 | 0.0003 | 0.0018 | 0.0020 | 0.0202 | 0.0756 | 0.1282 | 0.0992 | 0.1368 | 0.5359 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1125 | 641 | 11752 | 25342 | 232.5 | 61.19 | 170.59 | 255.96 | 162 | 186 | 201 | 215 | 228 | 242 | 257 | 278 | 310 | 0.0510 | 1293 | 1.092 | 30.46 | 9.43 | 3 | 0.0062 | 73 | 0.0008 | 52.10 | 7.510 | 0.1713 | 57786.2 | 15300000 | 4280000000 | 1270000000000 | 0.4266 | 0.2087 | 0.0003 | 0.0000 | 0.0011 | 0.0002 | 0.0038 | 0.0004 | 0.0137 | 0.0016 | 0.0570 | 0.0194 | 0.1221 | 0.0376 | 0.1242 | 0.0374 | 0.1725 | 0.0532 | 0.5053 | 0.8503 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0015 | 0.0000 | 0.0056 | 0.0005 | 0.0238 | 0.0113 | 0.0480 | 0.0188 | 0.0513 | 0.0158 | 0.0752 | 0.0235 | 0.7940 | 0.9300 | 0.0039 | 0.0023 | 0.0117 | 0.0081 | 0.0174 | 0.0151 | 0.0516 | 0.0755 | 0.0951 | 0.1231 | 0.1428 | 0.1649 | 0.0872 | 0.1115 | 0.1228 | 0.1161 | 0.4674 | 0.3833 | 0.0018 | 0.0029 | 0.0093 | 0.0250 | 0.0622 | 0.0988 | 0.0949 | 0.1131 | 0.5921 | 9 | 12 | 17 | 32 | 58 | 95 | 152 | 272 | 534 | 0.0689 | 34.29 | 5.267 | 0.5297 | 94612.1 | 77200000 | 75700000000 | 83200000000000 | 0.3585 | 0.3278 | 0.0395 | 0.0012 | 0.1512 | 0.0108 | 0.2256 | 0.0794 | 0.1461 | 0.1072 | 0.1502 | 0.1684 | 0.1169 | 0.1823 | 0.0707 | 0.1281 | 0.0608 | 0.1168 | 0.0390 | 0.2056 | 0.0006 | 0.0003 | 0.0021 | 0.0014 | 0.0038 | 0.0026 | 0.0153 | 0.0136 | 0.0581 | 0.0480 | 0.0869 | 0.0812 | 0.0666 | 0.0586 | 0.0861 | 0.0828 | 0.6805 | 0.7116 | 0.0002 | 0.0007 | 0.0019 | 0.0034 | 0.0056 | 0.0081 | 0.0251 | 0.0236 | 0.0640 | 0.0649 | 0.0941 | 0.0908 | 0.0674 | 0.0685 | 0.0855 | 0.0777 | 0.6563 | 0.6622 | 0.0007 | 0.0013 | 0.0062 | 0.0194 | 0.0623 | 0.0938 | 0.0645 | 0.0859 | 0.6660 | |||
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 819 | 741 | 5979 | 6896 | 220.8 | 55.20 | 179.58 | 138.54 | 160 | 176 | 189 | 201 | 212 | 224 | 239 | 259 | 290 | 0.1115 | 769 | 1.055 | 105.12 | 32.02 | 1 | 0.0418 | 250 | 0.0010 | 54.65 | 7.224 | 0.1685 | 51796.9 | 13000000 | 3490000000 | 1010000000000 | 0.4435 | 0.2077 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0040 | 0.0000 | 0.0187 | 0.0015 | 0.0749 | 0.0195 | 0.1570 | 0.0462 | 0.1484 | 0.0436 | 0.1840 | 0.0676 | 0.4128 | 0.8214 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0000 | 0.0059 | 0.0002 | 0.0381 | 0.0134 | 0.0733 | 0.0232 | 0.0677 | 0.0209 | 0.1008 | 0.0375 | 0.7133 | 0.9047 | 0.0048 | 0.0024 | 0.0107 | 0.0000 | 0.0213 | 0.0095 | 0.0804 | 0.0735 | 0.1231 | 0.1659 | 0.1841 | 0.2109 | 0.0940 | 0.0948 | 0.1260 | 0.1469 | 0.3556 | 0.2962 | 0.0016 | 0.0020 | 0.0102 | 0.0317 | 0.0939 | 0.1412 | 0.1146 | 0.1451 | 0.4597 | 35 | 59 | 83 | 111 | 142 | 182 | 230 | 292 | 373 | 0.0020 | 58.17 | 6.937 | 0.2558 | 51437.9 | 19300000 | 8700000000 | 4480000000000 | 0.5354 | 0.1275 | 0.0234 | 0.0012 | 0.1292 | 0.0079 | 0.2559 | 0.0540 | 0.1882 | 0.1092 | 0.1683 | 0.1926 | 0.1110 | 0.1934 | 0.0642 | 0.1357 | 0.0399 | 0.1274 | 0.0199 | 0.1785 | 0.0000 | 0.0000 | 0.0012 | 0.0007 | 0.0041 | 0.0040 | 0.0199 | 0.0119 | 0.0809 | 0.0632 | 0.1232 | 0.1038 | 0.0870 | 0.0722 | 0.1300 | 0.1109 | 0.5537 | 0.6333 | 0.0022 | 0.0006 | 0.0018 | 0.0033 | 0.0106 | 0.0155 | 0.0343 | 0.0472 | 0.1004 | 0.1210 | 0.1612 | 0.1805 | 0.1233 | 0.1260 | 0.1440 | 0.1460 | 0.4223 | 0.3598 | 0.0018 | 0.0029 | 0.0068 | 0.0310 | 0.0863 | 0.1320 | 0.1059 | 0.1469 | 0.4864 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 972 | 297 | 4771 | 7211 | 303.5 | 65.31 | 240.93 | 226.65 | 218 | 246 | 266 | 285 | 301 | 318 | 336 | 359 | 393 | 0.1144 | 825 | 0.746 | 99.85 | 18.25 | 1 | 0.0470 | 224 | 0.0006 | 79.54 | 7.546 | 0.1380 | 96372.4 | 31900000 | 11000000000 | 3900000000000 | 0.4166 | 0.2336 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0180 | 0.0018 | 0.0709 | 0.0195 | 0.1275 | 0.0424 | 0.1468 | 0.0462 | 0.1774 | 0.0735 | 0.4551 | 0.8167 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0004 | 0.0315 | 0.0150 | 0.0601 | 0.0295 | 0.0668 | 0.0242 | 0.0840 | 0.0406 | 0.7492 | 0.8903 | 0.0069 | 0.0237 | 0.0183 | 0.0473 | 0.0171 | 0.1065 | 0.0674 | 0.1598 | 0.1063 | 0.2189 | 0.1337 | 0.1479 | 0.1029 | 0.0651 | 0.1349 | 0.0947 | 0.4126 | 0.1361 | 0.0004 | 0.0004 | 0.0056 | 0.0299 | 0.0837 | 0.1205 | 0.1008 | 0.1166 | 0.5421 | 18 | 24 | 51 | 105 | 176 | 253 | 344 | 445 | 581 | 0.0200 | 42.53 | 6.319 | 0.3498 | 109411.0 | 62100000 | 40100000000 | 28400000000000 | 0.5244 | 0.1362 | 0.0141 | 0.0041 | 0.1315 | 0.0113 | 0.1984 | 0.0504 | 0.1737 | 0.0989 | 0.2007 | 0.1819 | 0.1080 | 0.2044 | 0.0869 | 0.1380 | 0.0552 | 0.1220 | 0.0317 | 0.1890 | 0.0003 | 0.0000 | 0.0020 | 0.0008 | 0.0014 | 0.0013 | 0.0098 | 0.0072 | 0.0571 | 0.0424 | 0.0704 | 0.0721 | 0.0637 | 0.0570 | 0.0947 | 0.0816 | 0.7006 | 0.7377 | 0.0004 | 0.0005 | 0.0023 | 0.0027 | 0.0104 | 0.0068 | 0.0154 | 0.0263 | 0.0677 | 0.0693 | 0.0903 | 0.1014 | 0.0765 | 0.0928 | 0.1107 | 0.1241 | 0.6263 | 0.5761 | 0.0003 | 0.0027 | 0.0020 | 0.0140 | 0.0578 | 0.0905 | 0.0708 | 0.1002 | 0.6617 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 458 | 196 | 2487 | 4852 | 502.4 | 108.13 | 28.97 | 67.04 | 323 | 396 | 462 | 498 | 525 | 549 | 572 | 595 | 625 | 0.1008 | 489 | 1.136 | 122.50 | 41.00 | 3 | 0.1186 | 295 | 0.0011 | 45.67 | 6.999 | 0.1815 | 264107.0 | 144000000 | 80400000000 | 45900000000000 | 0.4074 | 0.2236 | 0.0000 | 0.0000 | 0.0007 | 0.0017 | 0.0013 | 0.0017 | 0.0137 | 0.0038 | 0.0586 | 0.0196 | 0.1036 | 0.0325 | 0.0971 | 0.0282 | 0.1153 | 0.0440 | 0.6098 | 0.8684 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0017 | 0.0036 | 0.0038 | 0.0214 | 0.0196 | 0.0300 | 0.0311 | 0.0254 | 0.0230 | 0.0376 | 0.0358 | 0.8821 | 0.8834 | 0.0000 | 0.0000 | 0.0093 | 0.5000 | 0.0231 | 0.5000 | 0.0579 | 0.0000 | 0.1435 | 0.0000 | 0.2176 | 0.0000 | 0.0995 | 0.0000 | 0.1435 | 0.0000 | 0.3056 | 0.0000 | 0.0000 | 0.0021 | 0.0027 | 0.0103 | 0.0397 | 0.0637 | 0.0582 | 0.0794 | 0.7440 | 7 | 9 | 10 | 12 | 13 | 16 | 20 | 25 | 39 | 0.2290 | 1.64 | 2.351 | 0.8187 | 5332.5 | 2350000 | 1240000000 | 703000000000 | 0.6224 | 0.1004 | 0.0481 | 0.0325 | 0.0611 | 0.0293 | 0.0722 | 0.0357 | 0.0907 | 0.0325 | 0.1389 | 0.0523 | 0.1889 | 0.0722 | 0.1611 | 0.1094 | 0.1333 | 0.1665 | 0.1056 | 0.4695 | 0.0208 | 0.0226 | 0.0271 | 0.0203 | 0.0253 | 0.0231 | 0.0316 | 0.0220 | 0.0479 | 0.0365 | 0.0949 | 0.0602 | 0.0723 | 0.0747 | 0.1102 | 0.1169 | 0.5700 | 0.6238 | 0.0212 | 0.0086 | 0.0194 | 0.0107 | 0.0212 | 0.0086 | 0.0300 | 0.0193 | 0.0423 | 0.0428 | 0.0758 | 0.0600 | 0.0406 | 0.0450 | 0.0882 | 0.0878 | 0.6614 | 0.7173 | 0.0202 | 0.0265 | 0.0277 | 0.0429 | 0.0542 | 0.0845 | 0.0605 | 0.0782 | 0.6053 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1208 | 205 | 6928 | 22071 | 341.7 | 78.65 | 108.42 | 121.55 | 242 | 273 | 297 | 318 | 338 | 358 | 381 | 406 | 444 | 0.0464 | 1025 | 0.821 | 127.02 | 32.56 | 1 | 0.0485 | 336 | 0.0010 | 44.29 | 7.174 | 0.1864 | 122938.0 | 46400000 | 18300000000 | 7530000000000 | 0.4442 | 0.2150 | 0.0005 | 0.0000 | 0.0009 | 0.0002 | 0.0054 | 0.0000 | 0.0289 | 0.0006 | 0.0774 | 0.0196 | 0.1548 | 0.0468 | 0.1496 | 0.0486 | 0.1733 | 0.0699 | 0.4092 | 0.8144 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0007 | 0.0000 | 0.0054 | 0.0001 | 0.0331 | 0.0134 | 0.0668 | 0.0319 | 0.0580 | 0.0246 | 0.0875 | 0.0358 | 0.7479 | 0.8940 | 0.0023 | 0.0124 | 0.0062 | 0.0155 | 0.0247 | 0.0310 | 0.0918 | 0.1455 | 0.1550 | 0.2012 | 0.1958 | 0.1827 | 0.1210 | 0.1022 | 0.1365 | 0.1269 | 0.2668 | 0.1827 | 0.0003 | 0.0015 | 0.0063 | 0.0271 | 0.0855 | 0.1353 | 0.1139 | 0.1317 | 0.4984 | 9 | 13 | 22 | 40 | 63 | 94 | 133 | 188 | 275 | 0.0306 | 13.52 | 5.344 | 0.4677 | 26526.8 | 9310000 | 4040000000 | 2020000000000 | 0.4133 | 0.2398 | 0.0339 | 0.0012 | 0.1396 | 0.0060 | 0.2401 | 0.0523 | 0.1953 | 0.1264 | 0.1400 | 0.1867 | 0.1291 | 0.2003 | 0.0747 | 0.1544 | 0.0331 | 0.1250 | 0.0141 | 0.1478 | 0.0006 | 0.0003 | 0.0014 | 0.0015 | 0.0028 | 0.0033 | 0.0161 | 0.0120 | 0.0537 | 0.0500 | 0.0941 | 0.0727 | 0.0729 | 0.0606 | 0.1043 | 0.0889 | 0.6540 | 0.7107 | 0.0007 | 0.0010 | 0.0031 | 0.0019 | 0.0047 | 0.0087 | 0.0232 | 0.0267 | 0.0849 | 0.0952 | 0.1181 | 0.1316 | 0.0860 | 0.0864 | 0.1223 | 0.1332 | 0.5570 | 0.5153 | 0.0002 | 0.0019 | 0.0039 | 0.0193 | 0.0666 | 0.1098 | 0.0796 | 0.1117 | 0.6070 |