High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 875 | 62 | | 1334 | 3820 | 91.9 | 21.30 | 105.54 | 80.69 | 68 | 74 | 80 | 85 | 90 | 95 | 100 | 106 | 117 | 0.1102 | 421 | 0.866 | 95.82 | 24.17 | 1 | 0.1807 | 241 | 0.0026 | 28.10 | 6.166 | 0.2282 | 8892.5 | 911642 | 99600000 | 11700000000 | 0.4476 | 0.2105 | 0.0034 | 0.0000 | 0.0056 | 0.0000 | 0.0213 | 0.0048 | 0.0369 | 0.0081 | 0.0884 | 0.0306 | 0.1432 | 0.0564 | 0.1454 | 0.0596 | 0.1946 | 0.0854 | 0.3613 | 0.7550 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0000 | 0.0157 | 0.0023 | 0.0507 | 0.0235 | 0.1005 | 0.0454 | 0.0811 | 0.0310 | 0.1180 | 0.0613 | 0.6267 | 0.8365 | 0.0419 | 0.0125 | 0.0366 | 0.0375 | 0.0628 | 0.1000 | 0.0785 | 0.1000 | 0.1937 | 0.2125 | 0.2042 | 0.1000 | 0.0628 | 0.0750 | 0.0995 | 0.1375 | 0.2199 | 0.2250 | 0.0016 | 0.0128 | 0.0096 | 0.0465 | 0.1348 | 0.1750 | 0.1236 | 0.1637 | 0.3323 | 28 | 40 | 52 | 68 | 85 | 105 | 126 | 153 | 212 | 0.0130 | 7.64 | 5.068 | 0.4624 | 17649.0 | 4150000 | 1240000000 | 442000000000 | 0.4801 | 0.1727 | 0.0158 | 0.0013 | 0.0706 | 0.0076 | 0.1364 | 0.0297 | 0.1583 | 0.0607 | 0.1754 | 0.1208 | 0.1851 | 0.1720 | 0.1218 | 0.1562 | 0.0938 | 0.1720 | 0.0426 | 0.2796 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0067 | 0.0050 | 0.0249 | 0.0184 | 0.0716 | 0.0537 | 0.1095 | 0.0910 | 0.0851 | 0.0746 | 0.1183 | 0.1065 | 0.5817 | 0.6491 | 0.0036 | 0.0062 | 0.0099 | 0.0075 | 0.0172 | 0.0249 | 0.0506 | 0.0634 | 0.1112 | 0.1045 | 0.1546 | 0.1505 | 0.1103 | 0.1256 | 0.1338 | 0.1381 | 0.4087 | 0.3794 | 0.0013 | 0.0072 | 0.0118 | 0.0301 | 0.0740 | 0.1382 | 0.0950 | 0.1434 | 0.4990 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 341 | 154 | | 3660 | 2741 | 145.1 | 40.32 | 362.39 | 193.78 | 100 | 113 | 122 | 131 | 139 | 148 | 158 | 173 | 199 | 0.1423 | 390 | 0.690 | 91.44 | 18.79 | 1 | 0.0628 | 230 | 0.0017 | 31.24 | 6.666 | 0.2130 | 22685.8 | 3840000 | 708000000 | 142000000000 | 0.4590 | 0.1971 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0099 | 0.0000 | 0.0292 | 0.0034 | 0.0887 | 0.0281 | 0.1651 | 0.0650 | 0.1547 | 0.0625 | 0.1731 | 0.0940 | 0.3774 | 0.7470 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0018 | 0.0000 | 0.0113 | 0.0020 | 0.0389 | 0.0146 | 0.0752 | 0.0346 | 0.0724 | 0.0242 | 0.0947 | 0.0466 | 0.7043 | 0.8781 | 0.0056 | 0.0031 | 0.0042 | 0.0061 | 0.0225 | 0.0429 | 0.0591 | 0.0982 | 0.1224 | 0.1595 | 0.1758 | 0.2178 | 0.1097 | 0.1012 | 0.1280 | 0.1380 | 0.3727 | 0.2331 | 0.0000 | 0.0056 | 0.0175 | 0.0437 | 0.0936 | 0.1392 | 0.1180 | 0.1311 | 0.4513 | 105 | 176 | 244 | 302 | 359 | 408 | 457 | 521 | 616 | 0.0007 | 113.79 | 7.416 | 0.1244 | 168859.0 | 91300000 | 54900000000 | 35900000000000 | 0.5411 | 0.1415 | 0.0040 | 0.0007 | 0.0464 | 0.0056 | 0.1300 | 0.0190 | 0.1950 | 0.0556 | 0.1963 | 0.0999 | 0.1817 | 0.1955 | 0.1300 | 0.1871 | 0.0756 | 0.1906 | 0.0411 | 0.2461 | 0.0000 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0049 | 0.0305 | 0.0148 | 0.0610 | 0.0473 | 0.1103 | 0.0976 | 0.1139 | 0.0867 | 0.1144 | 0.1114 | 0.5610 | 0.6358 | 0.0032 | 0.0082 | 0.0095 | 0.0148 | 0.0242 | 0.0346 | 0.0621 | 0.0824 | 0.1137 | 0.1466 | 0.1505 | 0.1928 | 0.1232 | 0.1285 | 0.1568 | 0.1450 | 0.3568 | 0.2471 | 0.0007 | 0.0015 | 0.0154 | 0.0308 | 0.0968 | 0.1357 | 0.1086 | 0.1519 | 0.4585 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 203 | 497 | | 8616 | 14575 | 174.6 | 44.13 | 171.91 | 149.45 | 122 | 138 | 150 | 161 | 171 | 181 | 192 | 207 | 232 | 0.0673 | 981 | 1.044 | 125.32 | 34.48 | 1 | 0.0331 | 285 | 0.0012 | 38.52 | 7.056 | 0.1977 | 32427.2 | 6400000 | 1340000000 | 300000000000 | 0.4569 | 0.1989 | 0.0000 | 0.0000 | 0.0017 | 0.0001 | 0.0078 | 0.0003 | 0.0287 | 0.0031 | 0.0888 | 0.0227 | 0.1586 | 0.0483 | 0.1617 | 0.0556 | 0.1808 | 0.0817 | 0.3720 | 0.7881 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0011 | 0.0383 | 0.0140 | 0.0683 | 0.0253 | 0.0693 | 0.0240 | 0.0973 | 0.0396 | 0.7154 | 0.8960 | 0.0043 | 0.0068 | 0.0129 | 0.0307 | 0.0302 | 0.0341 | 0.0851 | 0.1022 | 0.1424 | 0.1959 | 0.1763 | 0.1959 | 0.1128 | 0.1141 | 0.1375 | 0.1210 | 0.2984 | 0.1993 | 0.0015 | 0.0050 | 0.0118 | 0.0350 | 0.0866 | 0.1316 | 0.1178 | 0.1480 | 0.4626 | 22 | 43 | 68 | 99 | 135 | 170 | 218 | 279 | 376 | 0.0026 | 76.94 | 7.156 | 0.2520 | 51884.8 | 21400000 | 11000000000 | 6610000000000 | 0.4445 | 0.1894 | 0.0210 | 0.0006 | 0.0998 | 0.0058 | 0.1884 | 0.0378 | 0.1768 | 0.0812 | 0.1748 | 0.1518 | 0.1509 | 0.1963 | 0.0944 | 0.1541 | 0.0536 | 0.1491 | 0.0404 | 0.2232 | 0.0008 | 0.0002 | 0.0013 | 0.0005 | 0.0043 | 0.0019 | 0.0145 | 0.0096 | 0.0545 | 0.0413 | 0.1088 | 0.0813 | 0.0850 | 0.0660 | 0.1138 | 0.0944 | 0.6169 | 0.7048 | 0.0008 | 0.0011 | 0.0042 | 0.0066 | 0.0085 | 0.0130 | 0.0307 | 0.0414 | 0.0827 | 0.0900 | 0.1433 | 0.1572 | 0.1056 | 0.1118 | 0.1272 | 0.1359 | 0.4970 | 0.4431 | 0.0005 | 0.0029 | 0.0095 | 0.0225 | 0.0731 | 0.1165 | 0.1001 | 0.1229 | 0.5519 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 359 | 542 | | 4621 | 10762 | 146.2 | 33.43 | 222.69 | 177.49 | 107 | 118 | 125 | 134 | 142 | 151 | 161 | 172 | 191 | 0.0783 | 843 | 0.885 | 76.16 | 18.03 | 1 | 0.0390 | 180 | 0.0019 | 23.24 | 6.525 | 0.2373 | 22484.2 | 3640000 | 620000000 | 111000000000 | 0.4346 | 0.2115 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0058 | 0.0002 | 0.0194 | 0.0023 | 0.0890 | 0.0207 | 0.1549 | 0.0458 | 0.1876 | 0.0490 | 0.2146 | 0.0759 | 0.3279 | 0.8061 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0024 | 0.0002 | 0.0059 | 0.0009 | 0.0386 | 0.0147 | 0.0709 | 0.0249 | 0.0768 | 0.0190 | 0.1183 | 0.0332 | 0.6866 | 0.9071 | 0.0061 | 0.0150 | 0.0207 | 0.0187 | 0.0292 | 0.0487 | 0.0901 | 0.1423 | 0.1681 | 0.1723 | 0.1791 | 0.2247 | 0.1108 | 0.1086 | 0.1462 | 0.1236 | 0.2497 | 0.1461 | 0.0009 | 0.0043 | 0.0080 | 0.0326 | 0.0913 | 0.1456 | 0.1210 | 0.1504 | 0.4459 | 44 | 73 | 105 | 144 | 183 | 226 | 275 | 342 | 445 | 0.0015 | 74.52 | 7.246 | 0.2302 | 81090.3 | 40900000 | 26000000000 | 19500000000000 | 0.4630 | 0.1957 | 0.0142 | 0.0014 | 0.0752 | 0.0062 | 0.1565 | 0.0283 | 0.1896 | 0.0627 | 0.1844 | 0.1479 | 0.1697 | 0.2060 | 0.1092 | 0.1512 | 0.0700 | 0.1579 | 0.0312 | 0.2384 | 0.0009 | 0.0003 | 0.0020 | 0.0012 | 0.0062 | 0.0036 | 0.0222 | 0.0121 | 0.0621 | 0.0464 | 0.1076 | 0.0967 | 0.0994 | 0.0695 | 0.1261 | 0.1058 | 0.5735 | 0.6645 | 0.0015 | 0.0019 | 0.0047 | 0.0070 | 0.0174 | 0.0174 | 0.0375 | 0.0557 | 0.0962 | 0.1161 | 0.1535 | 0.1663 | 0.1125 | 0.1199 | 0.1367 | 0.1389 | 0.4401 | 0.3768 | 0.0007 | 0.0043 | 0.0107 | 0.0285 | 0.0859 | 0.1281 | 0.1071 | 0.1381 | 0.4965 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 799 | 497 | | 16816 | 24748 | 122.3 | 34.96 | 236.76 | 206.30 | 82 | 94 | 102 | 110 | 118 | 126 | 136 | 149 | 168 | 0.0650 | 1609 | 1.118 | 72.20 | 25.02 | 3 | 0.0108 | 181 | 0.0021 | 18.82 | 6.539 | 0.2763 | 16190.9 | 2320000 | 358000000 | 60000000000 | 0.4389 | 0.2098 | 0.0010 | 0.0001 | 0.0025 | 0.0003 | 0.0091 | 0.0014 | 0.0328 | 0.0040 | 0.0891 | 0.0250 | 0.1521 | 0.0565 | 0.1545 | 0.0597 | 0.1758 | 0.0901 | 0.3831 | 0.7630 | 0.0004 | 0.0001 | 0.0005 | 0.0000 | 0.0026 | 0.0002 | 0.0095 | 0.0013 | 0.0356 | 0.0130 | 0.0650 | 0.0262 | 0.0618 | 0.0238 | 0.0849 | 0.0395 | 0.7396 | 0.8959 | 0.0031 | 0.0096 | 0.0075 | 0.0071 | 0.0173 | 0.0199 | 0.0537 | 0.1065 | 0.1221 | 0.1508 | 0.1553 | 0.2060 | 0.1205 | 0.1232 | 0.1477 | 0.1521 | 0.3728 | 0.2246 | 0.0013 | 0.0031 | 0.0088 | 0.0298 | 0.0749 | 0.1135 | 0.0977 | 0.1296 | 0.5413 | 21 | 45 | 86 | 134 | 187 | 246 | 312 | 397 | 532 | 0.0053 | 78.87 | 7.190 | 0.2785 | 98609.0 | 53500000 | 34300000000 | 24800000000000 | 0.5106 | 0.1669 | 0.0256 | 0.0012 | 0.1110 | 0.0083 | 0.2322 | 0.0422 | 0.1927 | 0.1005 | 0.1604 | 0.1805 | 0.1290 | 0.2104 | 0.0825 | 0.1584 | 0.0439 | 0.1366 | 0.0227 | 0.1620 | 0.0004 | 0.0002 | 0.0009 | 0.0012 | 0.0050 | 0.0019 | 0.0154 | 0.0099 | 0.0609 | 0.0492 | 0.1064 | 0.0949 | 0.0889 | 0.0752 | 0.1192 | 0.1063 | 0.6028 | 0.6612 | 0.0004 | 0.0013 | 0.0032 | 0.0039 | 0.0100 | 0.0142 | 0.0294 | 0.0412 | 0.0896 | 0.1025 | 0.1454 | 0.1529 | 0.1084 | 0.1139 | 0.1346 | 0.1366 | 0.4791 | 0.4335 | 0.0001 | 0.0020 | 0.0079 | 0.0209 | 0.0743 | 0.1266 | 0.1001 | 0.1318 | 0.5361 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1161 | 623 | | 4896 | 12890 | 292.1 | 122.93 | 77.58 | 156.83 | 140 | 170 | 195 | 234 | 275 | 322 | 378 | 426 | 471 | 0.0714 | 920 | 0.771 | 63.56 | 16.03 | 4 | 0.0327 | 160 | 0.0010 | 16.01 | 7.132 | 0.2695 | 100453.0 | 38700000 | 16000000000 | 6940000000000 | 0.3486 | 0.2680 | 0.0008 | 0.0004 | 0.0008 | 0.0015 | 0.0008 | 0.0030 | 0.0194 | 0.0109 | 0.0891 | 0.0449 | 0.1336 | 0.0612 | 0.1263 | 0.0581 | 0.1571 | 0.0849 | 0.4721 | 0.7350 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0003 | 0.0018 | 0.0061 | 0.0047 | 0.0187 | 0.0171 | 0.0224 | 0.0237 | 0.0252 | 0.0179 | 0.0330 | 0.0339 | 0.8936 | 0.9006 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0035 | 0.0053 | 0.0087 | 0.0381 | 0.0582 | 0.0545 | 0.0582 | 0.0393 | 0.0616 | 0.0527 | 0.0851 | 0.8102 | 0.7240 | 0.0000 | 0.0004 | 0.0009 | 0.0035 | 0.0274 | 0.0363 | 0.0314 | 0.0456 | 0.8544 | 7 | 9 | 11 | 13 | 17 | 25 | 42 | 84 | 223 | 0.1061 | 17.09 | 3.929 | 0.6640 | 30613.2 | 21000000 | 18400000000 | 18500000000000 | 0.3956 | 0.2278 | 0.0335 | 0.0066 | 0.0911 | 0.0183 | 0.1580 | 0.0374 | 0.2026 | 0.0682 | 0.2286 | 0.1364 | 0.1283 | 0.1540 | 0.1022 | 0.1393 | 0.0353 | 0.1598 | 0.0204 | 0.2801 | 0.0027 | 0.0025 | 0.0047 | 0.0030 | 0.0047 | 0.0050 | 0.0097 | 0.0116 | 0.0484 | 0.0449 | 0.0684 | 0.0581 | 0.0494 | 0.0512 | 0.0735 | 0.0722 | 0.7386 | 0.7516 | 0.0004 | 0.0009 | 0.0004 | 0.0004 | 0.0033 | 0.0035 | 0.0114 | 0.0097 | 0.0521 | 0.0578 | 0.0720 | 0.0843 | 0.0606 | 0.0618 | 0.0781 | 0.0856 | 0.7216 | 0.6961 | 0.0004 | 0.0011 | 0.0026 | 0.0086 | 0.0474 | 0.0784 | 0.0523 | 0.0732 | 0.7359 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1165 | 419 | | 423 | 1848 | 89.8 | 13.38 | 5.99 | 2.24 | 70 | 76 | 82 | 87 | 92 | 96 | 99 | 102 | 106 | 0.1580 | 292 | 0.987 | 101.21 | 28.84 | 2 | 0.5816 | 246 | 0.0855 | 0.62 | 2.720 | 0.7418 | 8238.7 | 771134 | 73500000 | 7110000000 | 0.4178 | 0.2216 | 0.0000 | 0.0000 | 0.0060 | 0.0000 | 0.0149 | 0.0000 | 0.0268 | 0.0071 | 0.0893 | 0.0567 | 0.1220 | 0.0946 | 0.1369 | 0.0520 | 0.1964 | 0.0827 | 0.4077 | 0.7069 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0109 | 0.0000 | 0.0218 | 0.0071 | 0.0708 | 0.0567 | 0.0627 | 0.0946 | 0.0518 | 0.0520 | 0.0681 | 0.0827 | 0.7084 | 0.7069 | 0.0968 | 0.0000 | 0.2581 | 0.0000 | 0.2581 | 0.0000 | 0.1613 | 0.0000 | 0.0968 | 0.0000 | 0.0968 | 0.0000 | 0.0323 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.0213 | 0.0383 | 0.0553 | 0.0596 | 0.0851 | 0.1532 | 0.5745 | 3 | 4 | 5 | 6 | 6 | 6 | 7 | 8 | 9 | 0.0815 | 0.39 | 0.827 | 0.2673 | 40.9 | 306.966 | 2499.9 | 21880.8 | 0.5165 | 0.1403 | 0.0116 | 0.0008 | 0.0474 | 0.0055 | 0.1063 | 0.0444 | 0.2358 | 0.1014 | 0.2716 | 0.1846 | 0.1884 | 0.2472 | 0.1011 | 0.2274 | 0.0316 | 0.1450 | 0.0063 | 0.0436 | 0.0000 | 0.0000 | 0.0041 | 0.0020 | 0.0186 | 0.0118 | 0.0592 | 0.0341 | 0.1171 | 0.1076 | 0.1860 | 0.1594 | 0.2404 | 0.2270 | 0.2424 | 0.2782 | 0.1322 | 0.1798 | 0.1036 | 0.3053 | 0.2490 | 0.2824 | 0.2829 | 0.1756 | 0.1972 | 0.0954 | 0.1056 | 0.0916 | 0.0418 | 0.0305 | 0.0179 | 0.0153 | 0.0020 | 0.0038 | 0.0000 | 0.0000 | 0.0026 | 0.0290 | 0.0729 | 0.1747 | 0.2186 | 0.2151 | 0.1449 | 0.1010 | 0.0413 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 620 | 230 | | 4285 | 3286 | 144.3 | 36.47 | 138.38 | 91.26 | 103 | 114 | 122 | 130 | 138 | 148 | 158 | 173 | 194 | 0.1869 | 614 | 1.042 | 86.49 | 33.29 | 1 | 0.0567 | 243 | 0.0019 | 26.80 | 6.577 | 0.2264 | 22156.9 | 3620000 | 632000000 | 117000000000 | 0.4068 | 0.2461 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0068 | 0.0008 | 0.0409 | 0.0036 | 0.0895 | 0.0250 | 0.1604 | 0.0595 | 0.1805 | 0.0680 | 0.1781 | 0.0883 | 0.3406 | 0.7550 | 0.0003 | 0.0000 | 0.0015 | 0.0000 | 0.0033 | 0.0007 | 0.0152 | 0.0019 | 0.0396 | 0.0150 | 0.0677 | 0.0307 | 0.0793 | 0.0309 | 0.0999 | 0.0421 | 0.6933 | 0.8786 | 0.0023 | 0.0063 | 0.0058 | 0.0284 | 0.0232 | 0.0473 | 0.0719 | 0.1356 | 0.1241 | 0.1703 | 0.1694 | 0.2177 | 0.1230 | 0.1041 | 0.1381 | 0.1104 | 0.3422 | 0.1798 | 0.0011 | 0.0074 | 0.0079 | 0.0370 | 0.0894 | 0.1174 | 0.1259 | 0.1364 | 0.4775 | 49 | 67 | 82 | 100 | 117 | 136 | 159 | 195 | 252 | 0.0034 | 28.02 | 6.143 | 0.3124 | 27476.4 | 7420000 | 2560000000 | 1060000000000 | 0.5807 | 0.0980 | 0.0129 | 0.0006 | 0.0526 | 0.0104 | 0.1671 | 0.0245 | 0.1542 | 0.0736 | 0.1916 | 0.1373 | 0.1729 | 0.1674 | 0.1320 | 0.1582 | 0.0713 | 0.1398 | 0.0456 | 0.2882 | 0.0006 | 0.0000 | 0.0034 | 0.0030 | 0.0130 | 0.0039 | 0.0419 | 0.0226 | 0.1058 | 0.0826 | 0.1533 | 0.1274 | 0.1250 | 0.1044 | 0.1408 | 0.1261 | 0.4163 | 0.5298 | 0.0066 | 0.0075 | 0.0055 | 0.0105 | 0.0362 | 0.0359 | 0.0768 | 0.0734 | 0.1480 | 0.1722 | 0.1612 | 0.1722 | 0.1261 | 0.1257 | 0.1469 | 0.1437 | 0.2928 | 0.2590 | 0.0023 | 0.0046 | 0.0201 | 0.0610 | 0.1251 | 0.1807 | 0.1127 | 0.1490 | 0.3444 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 404 | 381 | | 364 | 11109 | 91.1 | 12.14 | 8.23 | 2.31 | 76 | 80 | 84 | 87 | 91 | 94 | 97 | 101 | 107 | 0.0564 | 627 | 0.370 | 126.83 | 26.31 | 1 | 1.2060 | 439 | 0.0718 | 0.71 | 2.815 | 0.7088 | 8437.9 | 795470 | 76300000 | 7430000000 | 0.3908 | 0.2100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0192 | 0.0055 | 0.0895 | 0.0714 | 0.1789 | 0.1099 | 0.1278 | 0.0604 | 0.1917 | 0.1044 | 0.3930 | 0.6484 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0117 | 0.0055 | 0.0787 | 0.0714 | 0.1254 | 0.1099 | 0.0671 | 0.0604 | 0.1195 | 0.1044 | 0.5977 | 0.6484 | 0.0333 | 0.0000 | 0.0333 | 0.0000 | 0.0667 | 0.0000 | 0.2667 | 0.0000 | 0.1333 | 0.0000 | 0.2000 | 0.0000 | 0.0667 | 0.0000 | 0.0333 | 0.0000 | 0.1667 | 0.0000 | 0.0055 | 0.0055 | 0.0055 | 0.0546 | 0.1421 | 0.1694 | 0.1038 | 0.1639 | 0.3497 | 5 | 6 | 7 | 8 | 8 | 9 | 9 | 10 | 11 | 0.2651 | 0.45 | 1.038 | 0.6298 | 73.1 | 692.301 | 6934.55 | 73026.4 | 0.5150 | 0.1470 | 0.0084 | 0.0000 | 0.0454 | 0.0006 | 0.1209 | 0.0027 | 0.2055 | 0.0101 | 0.2489 | 0.0293 | 0.2133 | 0.0743 | 0.1150 | 0.1788 | 0.0368 | 0.3510 | 0.0059 | 0.3532 | 0.0002 | 0.0000 | 0.0024 | 0.0000 | 0.0090 | 0.0002 | 0.0345 | 0.0025 | 0.0902 | 0.0128 | 0.1613 | 0.0328 | 0.2251 | 0.0673 | 0.2757 | 0.2320 | 0.2014 | 0.6524 | 0.0871 | 0.3913 | 0.1762 | 0.3337 | 0.2103 | 0.1554 | 0.1847 | 0.0633 | 0.1500 | 0.0368 | 0.1089 | 0.0161 | 0.0537 | 0.0035 | 0.0237 | 0.0000 | 0.0054 | 0.0000 | 0.0034 | 0.0150 | 0.0465 | 0.1072 | 0.1765 | 0.2248 | 0.1975 | 0.1520 | 0.0770 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 781 | 933 | | 4650 | 7671 | 149.2 | 35.80 | 272.55 | 157.57 | 110 | 120 | 127 | 134 | 142 | 151 | 162 | 176 | 198 | 0.0948 | 727 | 1.075 | 97.75 | 27.80 | 1 | 0.0520 | 242 | 0.0020 | 26.81 | 6.558 | 0.2363 | 23531.1 | 3940000 | 699000000 | 132000000000 | 0.4493 | 0.1999 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0104 | 0.0002 | 0.0338 | 0.0009 | 0.0898 | 0.0243 | 0.1628 | 0.0471 | 0.1597 | 0.0468 | 0.1837 | 0.0695 | 0.3577 | 0.8111 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0002 | 0.0118 | 0.0004 | 0.0454 | 0.0150 | 0.0668 | 0.0232 | 0.0778 | 0.0163 | 0.1088 | 0.0306 | 0.6864 | 0.9142 | 0.0023 | 0.0030 | 0.0092 | 0.0060 | 0.0358 | 0.0329 | 0.0796 | 0.0928 | 0.1476 | 0.1707 | 0.1857 | 0.2335 | 0.1153 | 0.1138 | 0.1361 | 0.1707 | 0.2884 | 0.1766 | 0.0020 | 0.0035 | 0.0111 | 0.0308 | 0.0968 | 0.1402 | 0.1160 | 0.1452 | 0.4544 | 91 | 134 | 171 | 208 | 247 | 291 | 338 | 395 | 486 | 0.0007 | 96.75 | 7.538 | 0.1758 | 99105.9 | 44100000 | 22800000000 | 13300000000000 | 0.5485 | 0.1214 | 0.0151 | 0.0008 | 0.0764 | 0.0058 | 0.1871 | 0.0233 | 0.1861 | 0.0595 | 0.2027 | 0.1375 | 0.1554 | 0.2135 | 0.0941 | 0.1857 | 0.0520 | 0.1666 | 0.0312 | 0.2074 | 0.0009 | 0.0002 | 0.0030 | 0.0007 | 0.0077 | 0.0036 | 0.0219 | 0.0100 | 0.0743 | 0.0552 | 0.1272 | 0.1019 | 0.1078 | 0.0886 | 0.1429 | 0.1166 | 0.5144 | 0.6232 | 0.0008 | 0.0053 | 0.0106 | 0.0148 | 0.0203 | 0.0373 | 0.0519 | 0.0841 | 0.1339 | 0.1587 | 0.1729 | 0.1829 | 0.1303 | 0.1533 | 0.1652 | 0.1385 | 0.3141 | 0.2250 | 0.0009 | 0.0051 | 0.0146 | 0.0363 | 0.0991 | 0.1479 | 0.1303 | 0.1511 | 0.4148 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 162 | 234 | | 7241 | 33553 | 311.8 | 96.47 | 118.63 | 162.69 | 187 | 201 | 237 | 287 | 318 | 345 | 372 | 400 | 436 | 0.0350 | 1175 | 0.651 | 97.19 | 15.30 | 2 | 0.0305 | 221 | 0.0011 | 37.81 | 7.274 | 0.2128 | 106500.0 | 39100000 | 15200000000 | 6200000000000 | 0.4774 | 0.1776 | 0.0004 | 0.0012 | 0.0025 | 0.0024 | 0.0078 | 0.0057 | 0.0252 | 0.0134 | 0.0900 | 0.0431 | 0.1460 | 0.0745 | 0.1488 | 0.0709 | 0.1729 | 0.1150 | 0.4064 | 0.6737 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0012 | 0.0045 | 0.0020 | 0.0085 | 0.0163 | 0.0263 | 0.0285 | 0.0387 | 0.0281 | 0.0343 | 0.0386 | 0.0461 | 0.8853 | 0.8385 | 0.0024 | 0.0155 | 0.0043 | 0.0127 | 0.0119 | 0.0325 | 0.0396 | 0.0876 | 0.0835 | 0.1441 | 0.1098 | 0.1935 | 0.1150 | 0.1483 | 0.1394 | 0.1384 | 0.4940 | 0.2274 | 0.0000 | 0.0011 | 0.0029 | 0.0135 | 0.0296 | 0.0630 | 0.0643 | 0.0849 | 0.7407 | 9 | 11 | 14 | 19 | 34 | 73 | 138 | 222 | 342 | 0.1019 | 11.63 | 4.467 | 0.5909 | 40541.7 | 20200000 | 12600000000 | 9300000000000 | 0.3536 | 0.3217 | 0.0195 | 0.0035 | 0.1006 | 0.0081 | 0.1840 | 0.0477 | 0.1733 | 0.1043 | 0.1800 | 0.1722 | 0.1418 | 0.1779 | 0.1082 | 0.1344 | 0.0594 | 0.1368 | 0.0332 | 0.2151 | 0.0001 | 0.0006 | 0.0006 | 0.0005 | 0.0020 | 0.0011 | 0.0085 | 0.0076 | 0.0341 | 0.0295 | 0.0563 | 0.0485 | 0.0428 | 0.0362 | 0.0619 | 0.0541 | 0.7937 | 0.8219 | 0.0001 | 0.0002 | 0.0013 | 0.0015 | 0.0028 | 0.0035 | 0.0110 | 0.0135 | 0.0448 | 0.0478 | 0.0745 | 0.0869 | 0.0567 | 0.0645 | 0.0842 | 0.0980 | 0.7246 | 0.6843 | 0.0002 | 0.0009 | 0.0028 | 0.0099 | 0.0385 | 0.0629 | 0.0519 | 0.0705 | 0.7623 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 284 | 132 | | 3587 | 822 | 127.8 | 29.04 | 269.41 | 172.52 | 95 | 103 | 110 | 116 | 124 | 131 | 139 | 150 | 166 | 0.4538 | 373 | 0.730 | 52.80 | 16.97 | 1 | 0.0435 | 156 | 0.0026 | 19.75 | 6.264 | 0.2480 | 17172.9 | 2430000 | 364000000 | 57600000000 | 0.4499 | 0.2003 | 0.0013 | 0.0000 | 0.0039 | 0.0000 | 0.0057 | 0.0006 | 0.0284 | 0.0024 | 0.0900 | 0.0181 | 0.1429 | 0.0404 | 0.1608 | 0.0440 | 0.2172 | 0.0871 | 0.3497 | 0.8073 | 0.0007 | 0.0000 | 0.0031 | 0.0000 | 0.0021 | 0.0000 | 0.0106 | 0.0011 | 0.0398 | 0.0118 | 0.0621 | 0.0230 | 0.0648 | 0.0149 | 0.1204 | 0.0342 | 0.6964 | 0.9150 | 0.0048 | 0.0197 | 0.0207 | 0.0542 | 0.0287 | 0.0690 | 0.0813 | 0.1232 | 0.1643 | 0.1675 | 0.1978 | 0.1773 | 0.1372 | 0.1330 | 0.1547 | 0.1182 | 0.2105 | 0.1379 | 0.0025 | 0.0044 | 0.0176 | 0.0478 | 0.0806 | 0.1233 | 0.1296 | 0.1517 | 0.4424 | 69 | 114 | 153 | 190 | 229 | 286 | 352 | 427 | 520 | 0.0018 | 138.36 | 6.442 | 0.1434 | 102307.0 | 47200000 | 24500000000 | 13800000000000 | 0.3578 | 0.2281 | 0.0612 | 0.0059 | 0.2245 | 0.0413 | 0.3197 | 0.1150 | 0.1905 | 0.1475 | 0.1020 | 0.2448 | 0.0748 | 0.2035 | 0.0136 | 0.1091 | 0.0136 | 0.0973 | 0.0000 | 0.0354 | 0.0023 | 0.0018 | 0.0093 | 0.0161 | 0.0395 | 0.0233 | 0.0302 | 0.0376 | 0.1674 | 0.1485 | 0.2256 | 0.2093 | 0.1605 | 0.1503 | 0.1581 | 0.1807 | 0.2070 | 0.2326 | 0.0000 | 0.0045 | 0.0071 | 0.0227 | 0.0247 | 0.0455 | 0.0813 | 0.0818 | 0.2226 | 0.2682 | 0.2438 | 0.2182 | 0.1696 | 0.1591 | 0.1060 | 0.0682 | 0.1449 | 0.1318 | 0.0029 | 0.0086 | 0.0173 | 0.0490 | 0.1844 | 0.2478 | 0.1729 | 0.1499 | 0.1671 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1178 | 674 | | 5484 | 6809 | 143.9 | 34.02 | 169.15 | 111.62 | 106 | 116 | 124 | 131 | 139 | 147 | 156 | 168 | 188 | 0.1007 | 686 | 1.157 | 112.97 | 41.40 | 1 | 0.0514 | 282 | 0.0021 | 24.63 | 6.515 | 0.2364 | 21871.4 | 3520000 | 604000000 | 111000000000 | 0.4507 | 0.2018 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0058 | 0.0000 | 0.0260 | 0.0006 | 0.0901 | 0.0200 | 0.1435 | 0.0450 | 0.1588 | 0.0427 | 0.1805 | 0.0719 | 0.3939 | 0.8199 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0023 | 0.0000 | 0.0104 | 0.0000 | 0.0398 | 0.0138 | 0.0659 | 0.0247 | 0.0797 | 0.0192 | 0.1000 | 0.0332 | 0.7008 | 0.9092 | 0.0032 | 0.0155 | 0.0181 | 0.0217 | 0.0288 | 0.0342 | 0.0703 | 0.1025 | 0.1384 | 0.1460 | 0.1853 | 0.2267 | 0.1289 | 0.0932 | 0.1310 | 0.1211 | 0.2961 | 0.2391 | 0.0017 | 0.0041 | 0.0120 | 0.0398 | 0.0915 | 0.1441 | 0.1151 | 0.1416 | 0.4501 | 48 | 70 | 90 | 115 | 144 | 176 | 214 | 261 | 331 | 0.0020 | 39.25 | 6.753 | 0.2608 | 41068.8 | 12600000 | 4490000000 | 1800000000000 | 0.5577 | 0.1336 | 0.0189 | 0.0007 | 0.0769 | 0.0043 | 0.1858 | 0.0340 | 0.1829 | 0.0814 | 0.2010 | 0.1571 | 0.1647 | 0.2049 | 0.0885 | 0.1545 | 0.0508 | 0.1578 | 0.0305 | 0.2052 | 0.0008 | 0.0000 | 0.0022 | 0.0007 | 0.0047 | 0.0045 | 0.0230 | 0.0137 | 0.0604 | 0.0531 | 0.1187 | 0.0871 | 0.0787 | 0.0745 | 0.1281 | 0.1004 | 0.5833 | 0.6661 | 0.0022 | 0.0048 | 0.0049 | 0.0048 | 0.0153 | 0.0137 | 0.0431 | 0.0642 | 0.0969 | 0.1220 | 0.1620 | 0.1803 | 0.1184 | 0.1214 | 0.1463 | 0.1642 | 0.4109 | 0.3248 | 0.0017 | 0.0017 | 0.0098 | 0.0258 | 0.0834 | 0.1386 | 0.0988 | 0.1449 | 0.4951 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 380 | 140 | | 4015 | 11442 | 298.5 | 93.89 | 283.49 | 327.91 | 188 | 224 | 248 | 270 | 290 | 313 | 337 | 371 | 423 | 0.0718 | 821 | 0.641 | 110.89 | 16.16 | 3 | 0.0590 | 237 | 0.0005 | 119.77 | 7.721 | 0.1137 | 97912.3 | 34900000 | 13400000000 | 5490000000000 | 0.4228 | 0.1994 | 0.0000 | 0.0000 | 0.0005 | 0.0003 | 0.0078 | 0.0000 | 0.0352 | 0.0049 | 0.0906 | 0.0391 | 0.1684 | 0.0564 | 0.1361 | 0.0524 | 0.1522 | 0.0795 | 0.4092 | 0.7675 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0135 | 0.0016 | 0.0347 | 0.0237 | 0.0663 | 0.0307 | 0.0579 | 0.0234 | 0.0710 | 0.0373 | 0.7547 | 0.8833 | 0.0011 | 0.0093 | 0.0032 | 0.0023 | 0.0086 | 0.0163 | 0.0452 | 0.0629 | 0.0893 | 0.0979 | 0.1453 | 0.1375 | 0.0969 | 0.1235 | 0.1163 | 0.1142 | 0.4941 | 0.4359 | 0.0005 | 0.0005 | 0.0032 | 0.0244 | 0.0684 | 0.1087 | 0.0976 | 0.1124 | 0.5843 | 18 | 23 | 31 | 69 | 150 | 246 | 370 | 532 | 762 | 0.0260 | 64.88 | 6.232 | 0.4074 | 187886.0 | 166000000 | 173000000000 | 201000000000000 | 0.6183 | 0.1150 | 0.0315 | 0.0018 | 0.0954 | 0.0093 | 0.2028 | 0.0466 | 0.1778 | 0.0888 | 0.1759 | 0.1607 | 0.1389 | 0.1793 | 0.0880 | 0.1474 | 0.0528 | 0.1482 | 0.0370 | 0.2179 | 0.0008 | 0.0000 | 0.0015 | 0.0004 | 0.0054 | 0.0022 | 0.0149 | 0.0104 | 0.0492 | 0.0440 | 0.0677 | 0.0593 | 0.0620 | 0.0557 | 0.0989 | 0.0825 | 0.6996 | 0.7454 | 0.0014 | 0.0000 | 0.0038 | 0.0019 | 0.0049 | 0.0074 | 0.0181 | 0.0211 | 0.0585 | 0.0692 | 0.0937 | 0.0977 | 0.0766 | 0.0922 | 0.1110 | 0.1151 | 0.6320 | 0.5954 | 0.0005 | 0.0026 | 0.0062 | 0.0133 | 0.0554 | 0.0778 | 0.0700 | 0.1011 | 0.6730 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 855 | 295 | | 10991 | 23655 | 262.5 | 76.92 | 158.35 | 201.26 | 177 | 198 | 216 | 232 | 250 | 269 | 292 | 321 | 366 | 0.0567 | 1341 | 1.156 | 118.61 | 44.10 | 2 | 0.0278 | 305 | 0.0005 | 81.23 | 7.822 | 0.1418 | 74835.2 | 23200000 | 7750000000 | 2800000000000 | 0.4804 | 0.1627 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0071 | 0.0009 | 0.0294 | 0.0045 | 0.0907 | 0.0256 | 0.1763 | 0.0635 | 0.1516 | 0.0562 | 0.1834 | 0.0790 | 0.3603 | 0.7703 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0004 | 0.0117 | 0.0023 | 0.0349 | 0.0146 | 0.0759 | 0.0366 | 0.0625 | 0.0262 | 0.0909 | 0.0372 | 0.7224 | 0.8828 | 0.0004 | 0.0038 | 0.0059 | 0.0084 | 0.0143 | 0.0188 | 0.0412 | 0.0619 | 0.1017 | 0.1210 | 0.1509 | 0.1642 | 0.1076 | 0.1098 | 0.1366 | 0.1407 | 0.4414 | 0.3715 | 0.0008 | 0.0036 | 0.0096 | 0.0273 | 0.0644 | 0.1087 | 0.0818 | 0.1101 | 0.5937 | 10 | 12 | 15 | 20 | 43 | 109 | 209 | 323 | 476 | 0.0700 | 31.05 | 5.286 | 0.4973 | 65578.9 | 35100000 | 21700000000 | 15000000000000 | 0.5467 | 0.1326 | 0.0587 | 0.0020 | 0.2015 | 0.0205 | 0.3009 | 0.1523 | 0.1628 | 0.1523 | 0.1274 | 0.1764 | 0.0861 | 0.1946 | 0.0327 | 0.1099 | 0.0254 | 0.0900 | 0.0047 | 0.1020 | 0.0002 | 0.0002 | 0.0004 | 0.0001 | 0.0015 | 0.0005 | 0.0054 | 0.0054 | 0.0421 | 0.0359 | 0.0826 | 0.0761 | 0.0556 | 0.0480 | 0.0768 | 0.0648 | 0.7354 | 0.7690 | 0.0001 | 0.0000 | 0.0009 | 0.0009 | 0.0029 | 0.0031 | 0.0107 | 0.0130 | 0.0544 | 0.0570 | 0.1019 | 0.1180 | 0.0672 | 0.0698 | 0.0986 | 0.1004 | 0.6631 | 0.6377 | 0.0001 | 0.0002 | 0.0014 | 0.0079 | 0.0478 | 0.0936 | 0.0584 | 0.0901 | 0.7003 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 811 | 224 | | 3862 | 6781 | 328.4 | 152.30 | 138.02 | 238.95 | 140 | 175 | 209 | 260 | 309 | 370 | 436 | 481 | 535 | 0.0967 | 656 | 1.166 | 181.47 | 58.73 | 2 | 0.1144 | 442 | 0.0022 | 6.00 | 6.354 | 0.3863 | 131046.0 | 59300000 | 29000000000 | 15000000000000 | 0.3371 | 0.2738 | 0.0023 | 0.0005 | 0.0000 | 0.0011 | 0.0046 | 0.0043 | 0.0230 | 0.0097 | 0.0908 | 0.0500 | 0.1517 | 0.0844 | 0.1287 | 0.0580 | 0.1356 | 0.0876 | 0.4632 | 0.7045 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0048 | 0.0007 | 0.0205 | 0.0209 | 0.0301 | 0.0301 | 0.0261 | 0.0195 | 0.0305 | 0.0280 | 0.8872 | 0.9005 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0007 | 0.0052 | 0.0091 | 0.0207 | 0.0252 | 0.0342 | 0.0379 | 0.0726 | 0.0344 | 0.0654 | 0.0456 | 0.0840 | 0.8471 | 0.7168 | 0.0000 | 0.0000 | 0.0022 | 0.0039 | 0.0257 | 0.0363 | 0.0262 | 0.0312 | 0.8745 | 11 | 14 | 19 | 24 | 34 | 55 | 99 | 200 | 413 | 0.0754 | 21.49 | 4.311 | 0.6192 | 76139.6 | 68600000 | 77600000000 | 100000000000000 | 0.5118 | 0.1375 | 0.0101 | 0.0061 | 0.0553 | 0.0073 | 0.1508 | 0.0340 | 0.1508 | 0.0643 | 0.2462 | 0.1541 | 0.1683 | 0.2184 | 0.0955 | 0.1311 | 0.0628 | 0.1226 | 0.0603 | 0.2621 | 0.0000 | 0.0014 | 0.0021 | 0.0023 | 0.0057 | 0.0027 | 0.0114 | 0.0099 | 0.0532 | 0.0537 | 0.0749 | 0.0722 | 0.0583 | 0.0550 | 0.0800 | 0.0753 | 0.7145 | 0.7276 | 0.0000 | 0.0000 | 0.0039 | 0.0022 | 0.0039 | 0.0036 | 0.0123 | 0.0129 | 0.0578 | 0.0646 | 0.0884 | 0.0940 | 0.0676 | 0.0560 | 0.0799 | 0.0933 | 0.6862 | 0.6734 | 0.0006 | 0.0029 | 0.0053 | 0.0117 | 0.0516 | 0.0844 | 0.0668 | 0.0850 | 0.6917 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1239 | 302 | | 2914 | 11468 | 89.0 | 23.47 | 185.84 | 181.95 | 62 | 70 | 76 | 82 | 86 | 92 | 98 | 105 | 117 | 0.0557 | 639 | 1.081 | 95.21 | 32.02 | 1 | 0.0824 | 240 | 0.0040 | 15.08 | 5.828 | 0.3126 | 8469.4 | 866721 | 96000000 | 11600000000 | 0.4610 | 0.1943 | 0.0023 | 0.0000 | 0.0046 | 0.0011 | 0.0200 | 0.0027 | 0.0372 | 0.0057 | 0.0910 | 0.0289 | 0.1390 | 0.0427 | 0.1653 | 0.0632 | 0.2105 | 0.0967 | 0.3301 | 0.7589 | 0.0009 | 0.0000 | 0.0013 | 0.0004 | 0.0071 | 0.0000 | 0.0106 | 0.0014 | 0.0468 | 0.0195 | 0.0693 | 0.0287 | 0.0803 | 0.0337 | 0.1112 | 0.0553 | 0.6727 | 0.8611 | 0.0173 | 0.0000 | 0.0135 | 0.0406 | 0.0308 | 0.0508 | 0.0963 | 0.1015 | 0.1638 | 0.1929 | 0.1503 | 0.1675 | 0.1233 | 0.1168 | 0.1561 | 0.1269 | 0.2486 | 0.2030 | 0.0007 | 0.0045 | 0.0164 | 0.0425 | 0.0970 | 0.1231 | 0.1351 | 0.1552 | 0.4254 | 18 | 23 | 38 | 72 | 122 | 186 | 260 | 345 | 454 | 0.0125 | 51.50 | 6.479 | 0.3282 | 67639.0 | 31600000 | 17100000000 | 10300000000000 | 0.5344 | 0.1560 | 0.0634 | 0.0020 | 0.2146 | 0.0083 | 0.2992 | 0.1102 | 0.1675 | 0.1972 | 0.0951 | 0.2102 | 0.0764 | 0.1783 | 0.0472 | 0.1063 | 0.0187 | 0.0960 | 0.0179 | 0.0917 | 0.0002 | 0.0000 | 0.0004 | 0.0007 | 0.0031 | 0.0017 | 0.0183 | 0.0137 | 0.0645 | 0.0576 | 0.1169 | 0.1040 | 0.0833 | 0.0705 | 0.1163 | 0.1042 | 0.5970 | 0.6476 | 0.0010 | 0.0015 | 0.0027 | 0.0029 | 0.0067 | 0.0102 | 0.0284 | 0.0344 | 0.0832 | 0.0857 | 0.1256 | 0.1409 | 0.0964 | 0.1038 | 0.1348 | 0.1269 | 0.5211 | 0.4937 | 0.0009 | 0.0022 | 0.0037 | 0.0224 | 0.0757 | 0.1246 | 0.0944 | 0.1173 | 0.5588 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1018 | 411 | | 2600 | 6088 | 103.7 | 24.69 | 101.32 | 87.25 | 73 | 84 | 90 | 96 | 102 | 108 | 114 | 122 | 135 | 0.1304 | 794 | 0.757 | 122.10 | 28.23 | 2 | 0.1200 | 312 | 0.0039 | 11.20 | 5.825 | 0.3318 | 11365.0 | 1320000 | 161000000 | 21000000000 | 0.5268 | 0.1497 | 0.0006 | 0.0000 | 0.0037 | 0.0004 | 0.0141 | 0.0012 | 0.0263 | 0.0050 | 0.0912 | 0.0308 | 0.1769 | 0.0791 | 0.1622 | 0.0579 | 0.1714 | 0.0991 | 0.3537 | 0.7265 | 0.0005 | 0.0000 | 0.0014 | 0.0004 | 0.0038 | 0.0008 | 0.0100 | 0.0031 | 0.0491 | 0.0212 | 0.0920 | 0.0586 | 0.0734 | 0.0358 | 0.0972 | 0.0657 | 0.6725 | 0.8144 | 0.0043 | 0.0071 | 0.0259 | 0.0496 | 0.0237 | 0.0567 | 0.1034 | 0.1064 | 0.1315 | 0.2199 | 0.1810 | 0.1348 | 0.1099 | 0.1277 | 0.1142 | 0.1064 | 0.3060 | 0.1915 | 0.0033 | 0.0033 | 0.0181 | 0.0280 | 0.0954 | 0.1151 | 0.1127 | 0.1332 | 0.4910 | 24 | 33 | 44 | 57 | 72 | 91 | 120 | 163 | 222 | 0.0127 | 11.75 | 5.310 | 0.4411 | 17878.5 | 4610000 | 1580000000 | 681000000000 | 0.5373 | 0.1316 | 0.0246 | 0.0041 | 0.1026 | 0.0157 | 0.2041 | 0.0508 | 0.1688 | 0.1015 | 0.1709 | 0.1614 | 0.1368 | 0.1756 | 0.0887 | 0.1558 | 0.0641 | 0.1355 | 0.0395 | 0.1995 | 0.0022 | 0.0020 | 0.0051 | 0.0055 | 0.0091 | 0.0086 | 0.0215 | 0.0204 | 0.0680 | 0.0540 | 0.1066 | 0.0870 | 0.0844 | 0.0804 | 0.1135 | 0.1042 | 0.5897 | 0.6380 | 0.0022 | 0.0013 | 0.0039 | 0.0053 | 0.0061 | 0.0112 | 0.0259 | 0.0258 | 0.0783 | 0.0998 | 0.1517 | 0.1685 | 0.0998 | 0.1005 | 0.1224 | 0.1375 | 0.5097 | 0.4501 | 0.0027 | 0.0032 | 0.0163 | 0.0195 | 0.0736 | 0.1290 | 0.0940 | 0.1154 | 0.5463 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1099 | 456 | | 4384 | 11255 | 330.4 | 82.17 | 122.23 | 126.09 | 224 | 258 | 283 | 305 | 326 | 347 | 372 | 400 | 446 | 0.0782 | 880 | 1.074 | 91.24 | 29.15 | 1 | 0.0527 | 231 | 0.0005 | 119.89 | 7.749 | 0.1150 | 115898.0 | 42900000 | 16600000000 | 6700000000000 | 0.4213 | 0.2264 | 0.0004 | 0.0003 | 0.0004 | 0.0000 | 0.0020 | 0.0008 | 0.0145 | 0.0036 | 0.0912 | 0.0281 | 0.1739 | 0.0521 | 0.1546 | 0.0521 | 0.1784 | 0.0727 | 0.3846 | 0.7904 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0002 | 0.0038 | 0.0012 | 0.0353 | 0.0176 | 0.0695 | 0.0312 | 0.0601 | 0.0279 | 0.0917 | 0.0391 | 0.7384 | 0.8827 | 0.0032 | 0.0063 | 0.0032 | 0.0158 | 0.0222 | 0.0095 | 0.0549 | 0.0886 | 0.1267 | 0.1203 | 0.1426 | 0.2089 | 0.0971 | 0.1582 | 0.1204 | 0.1487 | 0.4298 | 0.2437 | 0.0019 | 0.0024 | 0.0081 | 0.0276 | 0.0676 | 0.1257 | 0.0995 | 0.1185 | 0.5488 | 12 | 17 | 26 | 41 | 66 | 110 | 167 | 231 | 315 | 0.0244 | 16.78 | 5.456 | 0.4535 | 30835.4 | 10200000 | 3890000000 | 1660000000000 | 0.5357 | 0.1392 | 0.0679 | 0.0019 | 0.2575 | 0.0224 | 0.3413 | 0.1296 | 0.1487 | 0.2072 | 0.0978 | 0.2115 | 0.0459 | 0.1648 | 0.0279 | 0.1034 | 0.0120 | 0.0858 | 0.0010 | 0.0734 | 0.0000 | 0.0000 | 0.0013 | 0.0002 | 0.0025 | 0.0033 | 0.0197 | 0.0144 | 0.0659 | 0.0599 | 0.1055 | 0.0938 | 0.0848 | 0.0719 | 0.1153 | 0.1097 | 0.6050 | 0.6468 | 0.0013 | 0.0012 | 0.0024 | 0.0024 | 0.0109 | 0.0115 | 0.0270 | 0.0329 | 0.0840 | 0.0922 | 0.1224 | 0.1351 | 0.1038 | 0.1031 | 0.1234 | 0.1278 | 0.5248 | 0.4938 | 0.0000 | 0.0014 | 0.0058 | 0.0175 | 0.0782 | 0.1175 | 0.0896 | 0.1249 | 0.5651 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 426 | 374 | | 4318 | 14420 | 143.7 | 34.49 | 119.50 | 125.97 | 103 | 114 | 123 | 131 | 140 | 148 | 158 | 170 | 188 | 0.0620 | 894 | 1.020 | 115.11 | 27.29 | 1 | 0.0602 | 260 | 0.0019 | 27.37 | 6.560 | 0.2321 | 21832.7 | 3510000 | 599000000 | 108000000000 | 0.4264 | 0.2220 | 0.0004 | 0.0000 | 0.0035 | 0.0005 | 0.0196 | 0.0012 | 0.0369 | 0.0027 | 0.0914 | 0.0222 | 0.1656 | 0.0530 | 0.1672 | 0.0527 | 0.1770 | 0.0782 | 0.3383 | 0.7894 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0000 | 0.0113 | 0.0014 | 0.0416 | 0.0148 | 0.0794 | 0.0319 | 0.0708 | 0.0195 | 0.1002 | 0.0380 | 0.6908 | 0.8945 | 0.0049 | 0.0114 | 0.0160 | 0.0114 | 0.0294 | 0.0456 | 0.0896 | 0.1787 | 0.1521 | 0.2129 | 0.1816 | 0.2053 | 0.1411 | 0.0913 | 0.1546 | 0.1293 | 0.2307 | 0.1141 | 0.0005 | 0.0031 | 0.0112 | 0.0386 | 0.0910 | 0.1352 | 0.1256 | 0.1546 | 0.4403 | 17 | 24 | 35 | 47 | 65 | 91 | 142 | 211 | 313 | 0.0080 | 38.15 | 6.234 | 0.3884 | 30147.3 | 10600000 | 4400000000 | 2040000000000 | 0.5107 | 0.1394 | 0.0427 | 0.0034 | 0.1280 | 0.0141 | 0.2110 | 0.0584 | 0.1420 | 0.1202 | 0.1528 | 0.1742 | 0.1412 | 0.1803 | 0.1009 | 0.1302 | 0.0559 | 0.1289 | 0.0256 | 0.1903 | 0.0007 | 0.0013 | 0.0025 | 0.0025 | 0.0054 | 0.0058 | 0.0116 | 0.0120 | 0.0497 | 0.0465 | 0.0797 | 0.0690 | 0.0606 | 0.0582 | 0.0869 | 0.0833 | 0.7029 | 0.7214 | 0.0002 | 0.0008 | 0.0009 | 0.0008 | 0.0044 | 0.0074 | 0.0114 | 0.0183 | 0.0634 | 0.0731 | 0.0992 | 0.1123 | 0.0727 | 0.0847 | 0.1113 | 0.1107 | 0.6365 | 0.5920 | 0.0004 | 0.0021 | 0.0035 | 0.0136 | 0.0496 | 0.0910 | 0.0683 | 0.0899 | 0.6816 | ||
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 380 | 183 | | 11039 | 18903 | 371.9 | 102.23 | 380.94 | 449.84 | 242 | 284 | 315 | 342 | 366 | 390 | 419 | 454 | 501 | 0.0627 | 1185 | 0.969 | 171.70 | 54.42 | 2 | 0.0400 | 442 | 0.0005 | 88.34 | 7.910 | 0.1324 | 148751.0 | 63700000 | 29100000000 | 14200000000000 | 0.4490 | 0.2026 | 0.0005 | 0.0000 | 0.0023 | 0.0001 | 0.0082 | 0.0004 | 0.0272 | 0.0029 | 0.0918 | 0.0254 | 0.1600 | 0.0644 | 0.1476 | 0.0628 | 0.1698 | 0.0955 | 0.3925 | 0.7484 | 0.0000 | 0.0000 | 0.0014 | 0.0001 | 0.0014 | 0.0002 | 0.0061 | 0.0012 | 0.0305 | 0.0163 | 0.0618 | 0.0383 | 0.0559 | 0.0283 | 0.0817 | 0.0492 | 0.7612 | 0.8664 | 0.0017 | 0.0049 | 0.0075 | 0.0233 | 0.0200 | 0.0331 | 0.0553 | 0.1129 | 0.1226 | 0.1755 | 0.1816 | 0.1718 | 0.1131 | 0.1055 | 0.1463 | 0.1313 | 0.3520 | 0.2417 | 0.0010 | 0.0019 | 0.0072 | 0.0234 | 0.0705 | 0.1244 | 0.0974 | 0.1322 | 0.5419 | 14 | 21 | 36 | 86 | 184 | 326 | 510 | 738 | 1059 | 0.0281 | 91.44 | 6.434 | 0.3906 | 347456.0 | 416000000 | 584000000000 | 919000000000000 | 0.5129 | 0.1516 | 0.0334 | 0.0012 | 0.1468 | 0.0085 | 0.2688 | 0.0832 | 0.1754 | 0.1376 | 0.1420 | 0.1939 | 0.1025 | 0.2057 | 0.0710 | 0.1331 | 0.0413 | 0.1056 | 0.0188 | 0.1313 | 0.0004 | 0.0001 | 0.0005 | 0.0002 | 0.0010 | 0.0015 | 0.0098 | 0.0078 | 0.0487 | 0.0404 | 0.0789 | 0.0691 | 0.0535 | 0.0457 | 0.0867 | 0.0737 | 0.7204 | 0.7615 | 0.0003 | 0.0002 | 0.0010 | 0.0016 | 0.0018 | 0.0031 | 0.0173 | 0.0236 | 0.0629 | 0.0721 | 0.1053 | 0.1168 | 0.0686 | 0.0778 | 0.1103 | 0.1157 | 0.6324 | 0.5891 | 0.0001 | 0.0003 | 0.0021 | 0.0129 | 0.0563 | 0.0923 | 0.0627 | 0.0991 | 0.6741 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 609 | 654 | | 7151 | 16942 | 197.2 | 47.67 | 158.72 | 128.62 | 142 | 158 | 169 | 180 | 191 | 204 | 217 | 235 | 262 | 0.0596 | 1009 | 1.165 | 114.14 | 40.26 | 1 | 0.0386 | 276 | 0.0010 | 44.53 | 7.179 | 0.1807 | 41154.1 | 9080000 | 2110000000 | 515000000000 | 0.4398 | 0.2146 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0034 | 0.0005 | 0.0225 | 0.0016 | 0.0918 | 0.0226 | 0.1658 | 0.0544 | 0.1623 | 0.0541 | 0.1830 | 0.0721 | 0.3699 | 0.7947 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0003 | 0.0087 | 0.0007 | 0.0377 | 0.0140 | 0.0650 | 0.0283 | 0.0655 | 0.0241 | 0.0987 | 0.0339 | 0.7223 | 0.8987 | 0.0043 | 0.0021 | 0.0080 | 0.0062 | 0.0217 | 0.0331 | 0.0810 | 0.1198 | 0.1389 | 0.1818 | 0.1975 | 0.2293 | 0.1172 | 0.1198 | 0.1404 | 0.1446 | 0.2909 | 0.1632 | 0.0015 | 0.0028 | 0.0067 | 0.0294 | 0.0781 | 0.1246 | 0.1136 | 0.1476 | 0.4957 | 29 | 50 | 73 | 98 | 124 | 154 | 195 | 255 | 340 | 0.0025 | 49.37 | 6.896 | 0.3087 | 41734.7 | 14900000 | 6570000000 | 3430000000000 | 0.4757 | 0.1683 | 0.0102 | 0.0005 | 0.0551 | 0.0051 | 0.1533 | 0.0172 | 0.1688 | 0.0526 | 0.1754 | 0.1321 | 0.1767 | 0.1793 | 0.1141 | 0.1494 | 0.0913 | 0.1597 | 0.0551 | 0.3041 | 0.0000 | 0.0002 | 0.0006 | 0.0008 | 0.0042 | 0.0018 | 0.0120 | 0.0073 | 0.0502 | 0.0359 | 0.0871 | 0.0632 | 0.0784 | 0.0546 | 0.1087 | 0.0842 | 0.6587 | 0.7522 | 0.0021 | 0.0007 | 0.0015 | 0.0035 | 0.0069 | 0.0106 | 0.0218 | 0.0308 | 0.0832 | 0.0946 | 0.1321 | 0.1464 | 0.1017 | 0.1114 | 0.1388 | 0.1415 | 0.5118 | 0.4604 | 0.0011 | 0.0012 | 0.0050 | 0.0180 | 0.0637 | 0.1167 | 0.0942 | 0.1257 | 0.5744 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1203 | 196 | | 3608 | 1256 | 112.8 | 33.02 | 56.49 | 42.34 | 79 | 87 | 93 | 99 | 105 | 112 | 122 | 134 | 156 | 0.4076 | 512 | 0.975 | 95.35 | 33.06 | 2 | 0.0734 | 265 | 0.0032 | 16.99 | 6.143 | 0.2879 | 13822.0 | 1860000 | 276000000 | 45100000000 | 0.3979 | 0.2576 | 0.0010 | 0.0003 | 0.0065 | 0.0006 | 0.0176 | 0.0028 | 0.0391 | 0.0056 | 0.0918 | 0.0314 | 0.1565 | 0.0637 | 0.1590 | 0.0566 | 0.1951 | 0.0942 | 0.3335 | 0.7448 | 0.0004 | 0.0000 | 0.0026 | 0.0000 | 0.0097 | 0.0008 | 0.0164 | 0.0025 | 0.0421 | 0.0200 | 0.0742 | 0.0382 | 0.0753 | 0.0306 | 0.1037 | 0.0514 | 0.6755 | 0.8564 | 0.0102 | 0.0029 | 0.0116 | 0.0117 | 0.0277 | 0.0264 | 0.0524 | 0.0733 | 0.1252 | 0.1554 | 0.1514 | 0.1525 | 0.1208 | 0.1202 | 0.1339 | 0.1320 | 0.3668 | 0.3255 | 0.0035 | 0.0085 | 0.0148 | 0.0318 | 0.0890 | 0.1329 | 0.1025 | 0.1576 | 0.4594 | 20 | 26 | 31 | 37 | 45 | 55 | 65 | 79 | 102 | 0.0171 | 7.89 | 4.661 | 0.4707 | 4982.0 | 681992 | 133000000 | 33000000000 | 0.5597 | 0.0948 | 0.0435 | 0.0159 | 0.1268 | 0.0336 | 0.1739 | 0.0814 | 0.1775 | 0.1310 | 0.1920 | 0.1717 | 0.1522 | 0.1664 | 0.0942 | 0.1451 | 0.0254 | 0.1469 | 0.0145 | 0.1080 | 0.0016 | 0.0073 | 0.0126 | 0.0085 | 0.0316 | 0.0208 | 0.0411 | 0.0403 | 0.1785 | 0.1404 | 0.2054 | 0.2088 | 0.1627 | 0.1416 | 0.1769 | 0.1844 | 0.1896 | 0.2479 | 0.0056 | 0.0197 | 0.0364 | 0.0630 | 0.0756 | 0.0709 | 0.1064 | 0.1102 | 0.2269 | 0.2283 | 0.1961 | 0.1811 | 0.1064 | 0.1457 | 0.1457 | 0.1220 | 0.1008 | 0.0591 | 0.0021 | 0.0123 | 0.0452 | 0.0903 | 0.2074 | 0.2177 | 0.1561 | 0.1335 | 0.1355 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 684 | 361 | | 399 | 6206 | 58.4 | 9.74 | 24.73 | 66.86 | 46 | 49 | 52 | 54 | 57 | 61 | 64 | 69 | 72 | 0.1017 | 631 | 0.682 | 36.24 | 8.54 | 1 | 0.2607 | 104 | 0.0248 | 2.23 | 3.908 | 0.5277 | 3503.6 | 215851 | 13600000 | 881000000 | 0.3536 | 0.2676 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0071 | 0.0000 | 0.0426 | 0.0101 | 0.0922 | 0.0628 | 0.1525 | 0.0678 | 0.1489 | 0.0653 | 0.1915 | 0.0879 | 0.3617 | 0.7060 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0225 | 0.0100 | 0.0535 | 0.0627 | 0.0817 | 0.0677 | 0.0789 | 0.0652 | 0.1042 | 0.0677 | 0.6563 | 0.7268 | 0.0137 | 1.0000 | 0.0000 | 0.0000 | 0.0274 | 0.0000 | 0.0822 | 0.0000 | 0.0822 | 0.0000 | 0.1781 | 0.0000 | 0.1370 | 0.0000 | 0.2055 | 0.0000 | 0.2740 | 0.0000 | 0.0053 | 0.0053 | 0.0159 | 0.0265 | 0.0635 | 0.1111 | 0.1058 | 0.0899 | 0.5767 | 5 | 6 | 7 | 8 | 9 | 10 | 13 | 18 | 40 | 0.3348 | 9.79 | 2.064 | 0.7707 | 5081.6 | 2730000 | 1940000000 | 1570000000000 | 0.6341 | 0.0846 | 0.0349 | 0.0330 | 0.1163 | 0.0366 | 0.1453 | 0.0425 | 0.1628 | 0.0837 | 0.2006 | 0.1262 | 0.1919 | 0.1498 | 0.1163 | 0.1462 | 0.0233 | 0.1686 | 0.0087 | 0.2134 | 0.0053 | 0.0181 | 0.0079 | 0.0194 | 0.0184 | 0.0148 | 0.0202 | 0.0258 | 0.0746 | 0.0523 | 0.0886 | 0.0690 | 0.0912 | 0.0800 | 0.1202 | 0.1052 | 0.5737 | 0.6155 | 0.0025 | 0.0028 | 0.0013 | 0.0000 | 0.0088 | 0.0043 | 0.0251 | 0.0256 | 0.0842 | 0.0954 | 0.1256 | 0.1439 | 0.0942 | 0.1068 | 0.1344 | 0.1296 | 0.5239 | 0.4915 | 0.0022 | 0.0098 | 0.0065 | 0.0271 | 0.0869 | 0.0912 | 0.0988 | 0.1325 | 0.5451 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 487 | 388 | | 17803 | 45389 | 157.0 | 50.28 | 154.36 | 177.24 | 92 | 114 | 128 | 142 | 155 | 168 | 183 | 200 | 225 | 0.0425 | 1928 | 1.251 | 24.52 | 7.81 | 5 | 0.0033 | 58 | 0.0011 | 27.12 | 7.140 | 0.2383 | 27189.4 | 5090000 | 1010000000 | 213000000000 | 0.4282 | 0.2106 | 0.0016 | 0.0001 | 0.0027 | 0.0011 | 0.0080 | 0.0022 | 0.0288 | 0.0083 | 0.0923 | 0.0292 | 0.1552 | 0.0530 | 0.1536 | 0.0615 | 0.1813 | 0.0892 | 0.3764 | 0.7554 | 0.0006 | 0.0001 | 0.0008 | 0.0008 | 0.0020 | 0.0012 | 0.0062 | 0.0038 | 0.0238 | 0.0118 | 0.0466 | 0.0193 | 0.0520 | 0.0202 | 0.0673 | 0.0299 | 0.8006 | 0.9130 | 0.0028 | 0.0076 | 0.0051 | 0.0076 | 0.0145 | 0.0286 | 0.0373 | 0.0753 | 0.0821 | 0.1201 | 0.1345 | 0.1711 | 0.1117 | 0.1287 | 0.1381 | 0.1368 | 0.4740 | 0.3241 | 0.0009 | 0.0019 | 0.0057 | 0.0186 | 0.0505 | 0.0897 | 0.0859 | 0.1121 | 0.6346 | 13 | 18 | 26 | 47 | 81 | 128 | 193 | 278 | 407 | 0.0395 | 20.75 | 5.394 | 0.5005 | 55240.7 | 27700000 | 16900000000 | 11900000000000 | 0.4247 | 0.2143 | 0.0378 | 0.0014 | 0.1492 | 0.0110 | 0.2622 | 0.0683 | 0.1893 | 0.1171 | 0.1504 | 0.1913 | 0.1095 | 0.1978 | 0.0586 | 0.1383 | 0.0341 | 0.1296 | 0.0088 | 0.1451 | 0.0003 | 0.0002 | 0.0011 | 0.0008 | 0.0022 | 0.0018 | 0.0130 | 0.0095 | 0.0518 | 0.0406 | 0.0919 | 0.0720 | 0.0661 | 0.0535 | 0.0987 | 0.0822 | 0.6750 | 0.7394 | 0.0006 | 0.0006 | 0.0012 | 0.0024 | 0.0051 | 0.0080 | 0.0184 | 0.0254 | 0.0735 | 0.0834 | 0.1248 | 0.1314 | 0.0862 | 0.0949 | 0.1190 | 0.1284 | 0.5712 | 0.5254 | 0.0004 | 0.0015 | 0.0030 | 0.0169 | 0.0596 | 0.1071 | 0.0813 | 0.1092 | 0.6210 |