High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 407 | 716 | | 7114 | 12770 | 534.1 | 94.65 | 61.96 | 146.06 | 380 | 451 | 508 | 534 | 555 | 577 | 594 | 611 | 633 | 0.0662 | 846 | 0.850 | 97.59 | 26.25 | 2 | 0.0417 | 297 | 0.0011 | 32.30 | 7.208 | 0.2276 | 294243.0 | 166000000 | 95600000000 | 55900000000000 | 0.4540 | 0.2027 | 0.0002 | 0.0001 | 0.0009 | 0.0006 | 0.0015 | 0.0003 | 0.0052 | 0.0017 | 0.0232 | 0.0121 | 0.0462 | 0.0176 | 0.0420 | 0.0150 | 0.0641 | 0.0232 | 0.8167 | 0.9294 | 0.0002 | 0.0001 | 0.0003 | 0.0006 | 0.0002 | 0.0003 | 0.0007 | 0.0017 | 0.0128 | 0.0121 | 0.0245 | 0.0176 | 0.0130 | 0.0150 | 0.0239 | 0.0232 | 0.9245 | 0.9294 | 0.0121 | 0.0000 | 0.0208 | 0.0000 | 0.0363 | 0.0000 | 0.0813 | 0.0000 | 0.1142 | 0.0000 | 0.1280 | 0.0000 | 0.1090 | 0.0000 | 0.1228 | 0.0000 | 0.3754 | 0.0000 | 0.0005 | 0.0014 | 0.0054 | 0.0119 | 0.0261 | 0.0428 | 0.0447 | 0.0612 | 0.8061 | 9 | 10 | 11 | 12 | 13 | 15 | 17 | 33 | 165 | 0.1905 | 3.26 | 2.362 | 0.6175 | 25171.9 | 16600000 | 13100000000 | 11600000000000 | 0.6507 | 0.0699 | 0.0193 | 0.0057 | 0.1322 | 0.0086 | 0.2204 | 0.0743 | 0.1736 | 0.1329 | 0.1267 | 0.2157 | 0.0909 | 0.1571 | 0.0716 | 0.0929 | 0.0661 | 0.1114 | 0.0992 | 0.2014 | 0.0000 | 0.0008 | 0.0009 | 0.0008 | 0.0031 | 0.0028 | 0.0098 | 0.0102 | 0.0459 | 0.0468 | 0.0570 | 0.0533 | 0.0459 | 0.0403 | 0.0731 | 0.0744 | 0.7643 | 0.7706 | 0.0011 | 0.0006 | 0.0021 | 0.0017 | 0.0069 | 0.0040 | 0.0133 | 0.0108 | 0.0436 | 0.0483 | 0.0760 | 0.0802 | 0.0452 | 0.0495 | 0.0803 | 0.0870 | 0.7315 | 0.7180 | 0.0005 | 0.0019 | 0.0048 | 0.0150 | 0.0446 | 0.0650 | 0.0509 | 0.0805 | 0.7368 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 587 | 223 | | 7211 | 12710 | 578.3 | 90.41 | 89.40 | 111.01 | 452 | 510 | 547 | 574 | 591 | 608 | 625 | 646 | 680 | 0.0629 | 799 | 0.795 | 89.56 | 23.85 | 3 | 0.0344 | 248 | 0.0009 | 62.64 | 7.370 | 0.1958 | 342572.0 | 207000000 | 127000000000 | 79600000000000 | 0.4491 | 0.1905 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0041 | 0.0004 | 0.0233 | 0.0117 | 0.0460 | 0.0246 | 0.0364 | 0.0110 | 0.0566 | 0.0202 | 0.8320 | 0.9321 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0004 | 0.0145 | 0.0117 | 0.0316 | 0.0246 | 0.0189 | 0.0110 | 0.0268 | 0.0179 | 0.9057 | 0.9343 | 0.0091 | 1.0000 | 0.0146 | 0.0000 | 0.0183 | 0.0000 | 0.0530 | 0.0000 | 0.0804 | 0.0000 | 0.1005 | 0.0000 | 0.1024 | 0.0000 | 0.0951 | 0.0000 | 0.5265 | 0.0000 | 0.0002 | 0.0019 | 0.0045 | 0.0124 | 0.0426 | 0.0660 | 0.0670 | 0.0881 | 0.7172 | 10 | 14 | 19 | 27 | 40 | 63 | 103 | 156 | 234 | 0.0268 | 20.05 | 5.200 | 0.4970 | 20313.0 | 7180000 | 3310000000 | 1810000000000 | 0.4322 | 0.2068 | 0.0263 | 0.0009 | 0.1259 | 0.0110 | 0.2488 | 0.0568 | 0.1902 | 0.1088 | 0.1746 | 0.1845 | 0.1190 | 0.2039 | 0.0576 | 0.1352 | 0.0371 | 0.1325 | 0.0205 | 0.1664 | 0.0006 | 0.0000 | 0.0021 | 0.0011 | 0.0049 | 0.0034 | 0.0148 | 0.0150 | 0.0490 | 0.0449 | 0.0884 | 0.0752 | 0.0504 | 0.0554 | 0.0762 | 0.0747 | 0.7136 | 0.7303 | 0.0008 | 0.0006 | 0.0022 | 0.0034 | 0.0048 | 0.0079 | 0.0202 | 0.0248 | 0.0619 | 0.0657 | 0.0967 | 0.1116 | 0.0695 | 0.0730 | 0.0948 | 0.0920 | 0.6491 | 0.6210 | 0.0000 | 0.0017 | 0.0031 | 0.0174 | 0.0513 | 0.0911 | 0.0613 | 0.0830 | 0.6913 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1168 | 309 | | 5738 | 14541 | 555.0 | 97.99 | 135.57 | 201.88 | 430 | 475 | 509 | 532 | 549 | 569 | 595 | 630 | 674 | 0.0558 | 812 | 1.022 | 61.39 | 19.31 | 1 | 0.0284 | 163 | 0.0013 | 20.75 | 6.963 | 0.2451 | 317645.0 | 187000000 | 114000000000 | 71800000000000 | 0.4110 | 0.2319 | 0.0002 | 0.0000 | 0.0005 | 0.0002 | 0.0016 | 0.0000 | 0.0094 | 0.0011 | 0.0237 | 0.0134 | 0.0434 | 0.0246 | 0.0556 | 0.0175 | 0.0657 | 0.0266 | 0.8000 | 0.9168 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0002 | 0.0111 | 0.0115 | 0.0231 | 0.0207 | 0.0271 | 0.0101 | 0.0293 | 0.0171 | 0.9045 | 0.9404 | 0.0060 | 0.0000 | 0.0119 | 0.0000 | 0.0179 | 0.0000 | 0.0448 | 0.0000 | 0.0746 | 0.0000 | 0.0896 | 0.0000 | 0.0940 | 0.0000 | 0.1284 | 0.0000 | 0.5328 | 0.0000 | 0.0037 | 0.0078 | 0.0108 | 0.0257 | 0.0310 | 0.0518 | 0.0567 | 0.0712 | 0.7411 | 6 | 9 | 11 | 15 | 31 | 63 | 129 | 257 | 447 | 0.0557 | 17.52 | 4.450 | 0.4770 | 59131.7 | 35000000 | 24100000000 | 18500000000000 | 0.2802 | 0.3316 | 0.0685 | 0.0029 | 0.2066 | 0.0315 | 0.2433 | 0.1562 | 0.1601 | 0.1358 | 0.1039 | 0.1713 | 0.0844 | 0.1871 | 0.0648 | 0.1125 | 0.0391 | 0.0857 | 0.0293 | 0.1171 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0017 | 0.0011 | 0.0106 | 0.0101 | 0.0494 | 0.0398 | 0.0811 | 0.0787 | 0.0552 | 0.0482 | 0.0684 | 0.0622 | 0.7334 | 0.7591 | 0.0000 | 0.0008 | 0.0005 | 0.0014 | 0.0036 | 0.0028 | 0.0137 | 0.0194 | 0.0588 | 0.0540 | 0.0975 | 0.1111 | 0.0629 | 0.0684 | 0.0890 | 0.0925 | 0.6741 | 0.6495 | 0.0002 | 0.0007 | 0.0019 | 0.0127 | 0.0514 | 0.0927 | 0.0561 | 0.0791 | 0.7052 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 431 | 339 | | 3943 | 10483 | 650.4 | 93.20 | 77.12 | 134.86 | 524 | 578 | 611 | 637 | 655 | 676 | 697 | 725 | 765 | 0.0630 | 660 | 1.066 | 99.30 | 32.65 | 1 | 0.0621 | 245 | 0.0013 | 29.21 | 6.926 | 0.2389 | 431670.0 | 292000000 | 201000000000 | 140000000000000 | 0.4337 | 0.2092 | 0.0006 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0043 | 0.0003 | 0.0239 | 0.0147 | 0.0347 | 0.0234 | 0.0340 | 0.0127 | 0.0534 | 0.0226 | 0.8476 | 0.9264 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0003 | 0.0148 | 0.0147 | 0.0235 | 0.0234 | 0.0179 | 0.0127 | 0.0277 | 0.0226 | 0.9140 | 0.9264 | 0.0065 | 0.0000 | 0.0065 | 0.0000 | 0.0226 | 0.0000 | 0.0355 | 0.0000 | 0.1000 | 0.0000 | 0.0871 | 0.0000 | 0.1065 | 0.0000 | 0.1290 | 0.0000 | 0.5065 | 0.0000 | 0.0000 | 0.0038 | 0.0072 | 0.0191 | 0.0401 | 0.0558 | 0.0615 | 0.0873 | 0.7252 | 6 | 8 | 9 | 11 | 14 | 22 | 53 | 125 | 238 | 0.1380 | 10.00 | 3.574 | 0.6077 | 24132.5 | 11700000 | 7110000000 | 4930000000000 | 0.4308 | 0.2239 | 0.0546 | 0.0060 | 0.1513 | 0.0313 | 0.2122 | 0.0625 | 0.1912 | 0.1159 | 0.1639 | 0.1915 | 0.1261 | 0.1935 | 0.0630 | 0.1381 | 0.0315 | 0.1190 | 0.0063 | 0.1421 | 0.0010 | 0.0000 | 0.0017 | 0.0015 | 0.0024 | 0.0033 | 0.0102 | 0.0118 | 0.0453 | 0.0386 | 0.0572 | 0.0477 | 0.0437 | 0.0443 | 0.0670 | 0.0641 | 0.7716 | 0.7887 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0020 | 0.0017 | 0.0113 | 0.0139 | 0.0577 | 0.0582 | 0.0658 | 0.0747 | 0.0516 | 0.0595 | 0.0791 | 0.0860 | 0.7313 | 0.7059 | 0.0004 | 0.0000 | 0.0015 | 0.0127 | 0.0470 | 0.0601 | 0.0548 | 0.0660 | 0.7576 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 260 | 906 | | 6741 | 5810 | 457.5 | 85.03 | 189.24 | 346.87 | 354 | 397 | 434 | 457 | 471 | 484 | 497 | 515 | 542 | 0.1139 | 662 | 0.726 | 107.34 | 27.78 | 4 | 0.0481 | 324 | 0.0013 | 28.66 | 7.062 | 0.2336 | 216541.0 | 105000000 | 52100000000 | 26300000000000 | 0.4404 | 0.2127 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0038 | 0.0000 | 0.0072 | 0.0011 | 0.0244 | 0.0142 | 0.0415 | 0.0371 | 0.0385 | 0.0169 | 0.0651 | 0.0290 | 0.8182 | 0.9017 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0026 | 0.0000 | 0.0044 | 0.0005 | 0.0175 | 0.0138 | 0.0303 | 0.0338 | 0.0218 | 0.0135 | 0.0322 | 0.0208 | 0.8903 | 0.9176 | 0.0174 | 0.0000 | 0.0209 | 0.0000 | 0.0192 | 0.0000 | 0.0314 | 0.0000 | 0.0401 | 0.0000 | 0.0627 | 0.0000 | 0.0592 | 0.0000 | 0.0941 | 0.0000 | 0.6551 | 0.0000 | 0.0007 | 0.0045 | 0.0057 | 0.0172 | 0.0314 | 0.0528 | 0.0617 | 0.0889 | 0.7372 | 15 | 17 | 18 | 21 | 27 | 55 | 114 | 280 | 602 | 0.2435 | 18.42 | 3.549 | 0.6966 | 156109.0 | 197000000 | 310000000000 | 567000000000000 | 0.6374 | 0.0658 | 0.0763 | 0.0000 | 0.1968 | 0.0329 | 0.2129 | 0.1024 | 0.1566 | 0.1225 | 0.1406 | 0.1846 | 0.1245 | 0.1554 | 0.0482 | 0.1280 | 0.0361 | 0.1188 | 0.0080 | 0.1554 | 0.0013 | 0.0000 | 0.0019 | 0.0006 | 0.0039 | 0.0023 | 0.0142 | 0.0138 | 0.0685 | 0.0619 | 0.0931 | 0.0865 | 0.0672 | 0.0613 | 0.1002 | 0.0980 | 0.6496 | 0.6756 | 0.0008 | 0.0000 | 0.0031 | 0.0025 | 0.0046 | 0.0067 | 0.0208 | 0.0200 | 0.0701 | 0.0835 | 0.1017 | 0.0943 | 0.0770 | 0.0760 | 0.1063 | 0.1077 | 0.6156 | 0.6093 | 0.0000 | 0.0014 | 0.0043 | 0.0157 | 0.0686 | 0.1029 | 0.0657 | 0.1064 | 0.6350 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 141 | 699 | | 7154 | 15239 | 575.9 | 95.31 | 29.74 | 48.68 | 449 | 502 | 533 | 558 | 579 | 601 | 622 | 652 | 696 | 0.0671 | 1023 | 0.931 | 90.61 | 28.60 | 3 | 0.0352 | 252 | 0.0011 | 31.86 | 7.150 | 0.2308 | 340741.0 | 207000000 | 128000000000 | 80800000000000 | 0.4150 | 0.2161 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0061 | 0.0006 | 0.0245 | 0.0127 | 0.0495 | 0.0227 | 0.0463 | 0.0142 | 0.0702 | 0.0222 | 0.8014 | 0.9276 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0025 | 0.0003 | 0.0155 | 0.0122 | 0.0287 | 0.0212 | 0.0234 | 0.0112 | 0.0340 | 0.0164 | 0.8955 | 0.9387 | 0.0066 | 0.0313 | 0.0131 | 0.1875 | 0.0210 | 0.0938 | 0.0329 | 0.1250 | 0.0631 | 0.1875 | 0.0972 | 0.1250 | 0.0907 | 0.0938 | 0.1196 | 0.1250 | 0.5558 | 0.0313 | 0.0011 | 0.0046 | 0.0060 | 0.0179 | 0.0447 | 0.0660 | 0.0690 | 0.0842 | 0.7066 | 6 | 8 | 9 | 10 | 12 | 15 | 21 | 33 | 71 | 0.1972 | 1.48 | 2.529 | 0.7147 | 3254.2 | 656547 | 165000000 | 46700000000 | 0.5056 | 0.1413 | 0.0414 | 0.0294 | 0.0670 | 0.0284 | 0.1535 | 0.0479 | 0.1859 | 0.0812 | 0.1934 | 0.1171 | 0.1618 | 0.1309 | 0.1106 | 0.1486 | 0.0640 | 0.2072 | 0.0226 | 0.2093 | 0.0062 | 0.0147 | 0.0081 | 0.0103 | 0.0180 | 0.0156 | 0.0240 | 0.0182 | 0.0531 | 0.0425 | 0.0837 | 0.0718 | 0.0721 | 0.0609 | 0.0963 | 0.1079 | 0.6385 | 0.6580 | 0.0031 | 0.0036 | 0.0076 | 0.0056 | 0.0132 | 0.0156 | 0.0287 | 0.0324 | 0.0651 | 0.0720 | 0.0970 | 0.0980 | 0.0707 | 0.0720 | 0.1050 | 0.1032 | 0.6096 | 0.5974 | 0.0052 | 0.0084 | 0.0102 | 0.0335 | 0.0664 | 0.0836 | 0.0740 | 0.0976 | 0.6210 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 465 | 643 | | 8720 | 12380 | 327.7 | 56.71 | 178.47 | 263.33 | 253 | 288 | 306 | 320 | 333 | 346 | 358 | 371 | 394 | 0.0826 | 1023 | 1.053 | 189.34 | 55.01 | 1 | 0.0515 | 449 | 0.0016 | 19.71 | 6.739 | 0.2552 | 110617.0 | 38300000 | 13500000000 | 4860000000000 | 0.4132 | 0.2316 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0010 | 0.0001 | 0.0059 | 0.0010 | 0.0246 | 0.0101 | 0.0541 | 0.0199 | 0.0557 | 0.0130 | 0.0950 | 0.0226 | 0.7636 | 0.9332 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0001 | 0.0030 | 0.0009 | 0.0126 | 0.0096 | 0.0228 | 0.0178 | 0.0228 | 0.0096 | 0.0370 | 0.0162 | 0.9017 | 0.9456 | 0.0114 | 0.0000 | 0.0227 | 0.0000 | 0.0272 | 0.0000 | 0.0681 | 0.0000 | 0.0988 | 0.0000 | 0.1703 | 0.0000 | 0.1067 | 0.0000 | 0.1226 | 0.0000 | 0.3723 | 0.0000 | 0.0008 | 0.0019 | 0.0071 | 0.0173 | 0.0483 | 0.0854 | 0.0861 | 0.1201 | 0.6330 | 18 | 25 | 36 | 52 | 72 | 98 | 148 | 262 | 503 | 0.0250 | 35.86 | 5.284 | 0.5431 | 101188.0 | 92200000 | 104000000000 | 133000000000000 | 0.5504 | 0.1103 | 0.0118 | 0.0028 | 0.0634 | 0.0052 | 0.1160 | 0.0282 | 0.1461 | 0.0612 | 0.1912 | 0.1266 | 0.1751 | 0.1507 | 0.1224 | 0.1351 | 0.0988 | 0.1573 | 0.0752 | 0.3329 | 0.0005 | 0.0002 | 0.0003 | 0.0011 | 0.0024 | 0.0023 | 0.0079 | 0.0094 | 0.0482 | 0.0428 | 0.0854 | 0.0656 | 0.0514 | 0.0563 | 0.0801 | 0.0808 | 0.7238 | 0.7415 | 0.0000 | 0.0000 | 0.0021 | 0.0008 | 0.0042 | 0.0035 | 0.0101 | 0.0097 | 0.0538 | 0.0635 | 0.0894 | 0.0884 | 0.0594 | 0.0666 | 0.0876 | 0.0970 | 0.6934 | 0.6706 | 0.0000 | 0.0003 | 0.0031 | 0.0089 | 0.0520 | 0.0851 | 0.0560 | 0.0875 | 0.7072 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 343 | 266 | | 9188 | 10970 | 380.5 | 50.11 | 368.80 | 331.03 | 317 | 338 | 353 | 366 | 379 | 392 | 407 | 423 | 446 | 0.0837 | 918 | 1.098 | 128.97 | 29.02 | 1 | 0.0293 | 269 | 0.0014 | 32.93 | 6.904 | 0.2140 | 147263.0 | 58000000 | 23200000000 | 9410000000000 | 0.4808 | 0.1754 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0047 | 0.0002 | 0.0250 | 0.0095 | 0.0514 | 0.0210 | 0.0529 | 0.0104 | 0.0987 | 0.0165 | 0.7665 | 0.9424 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0012 | 0.0001 | 0.0138 | 0.0095 | 0.0278 | 0.0207 | 0.0261 | 0.0093 | 0.0415 | 0.0143 | 0.8895 | 0.9462 | 0.0218 | 0.0000 | 0.0328 | 0.0000 | 0.0593 | 0.0000 | 0.0874 | 0.0000 | 0.1732 | 0.0000 | 0.1841 | 0.0000 | 0.1435 | 0.0000 | 0.1388 | 0.0000 | 0.1591 | 0.0000 | 0.0011 | 0.0040 | 0.0097 | 0.0303 | 0.0725 | 0.1067 | 0.1129 | 0.1309 | 0.5320 | 26 | 44 | 103 | 182 | 274 | 391 | 529 | 679 | 850 | 0.0115 | 87.23 | 6.899 | 0.3039 | 245585.0 | 203000000 | 190000000000 | 195000000000000 | 0.5450 | 0.1332 | 0.0240 | 0.0019 | 0.1159 | 0.0052 | 0.2589 | 0.0480 | 0.1785 | 0.1152 | 0.1414 | 0.1989 | 0.1291 | 0.2063 | 0.0765 | 0.1279 | 0.0433 | 0.1290 | 0.0325 | 0.1677 | 0.0004 | 0.0003 | 0.0015 | 0.0005 | 0.0044 | 0.0031 | 0.0158 | 0.0085 | 0.0472 | 0.0440 | 0.0846 | 0.0769 | 0.0584 | 0.0516 | 0.0824 | 0.0766 | 0.7053 | 0.7384 | 0.0003 | 0.0009 | 0.0025 | 0.0032 | 0.0058 | 0.0059 | 0.0156 | 0.0215 | 0.0666 | 0.0792 | 0.1115 | 0.1340 | 0.0860 | 0.1022 | 0.1267 | 0.1240 | 0.5849 | 0.5290 | 0.0000 | 0.0026 | 0.0050 | 0.0109 | 0.0579 | 0.0934 | 0.0690 | 0.0986 | 0.6626 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 910 | 235 | | 5650 | 9484 | 613.1 | 99.25 | 15.85 | 17.71 | 472 | 537 | 575 | 601 | 623 | 643 | 663 | 690 | 733 | 0.0777 | 737 | 0.760 | 87.05 | 15.26 | 1 | 0.0388 | 219 | 0.0011 | 30.87 | 7.107 | 0.2252 | 385716.0 | 248000000 | 163000000000 | 109000000000000 | 0.3922 | 0.2485 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0043 | 0.0007 | 0.0256 | 0.0133 | 0.0488 | 0.0204 | 0.0442 | 0.0136 | 0.0551 | 0.0226 | 0.8197 | 0.9294 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0007 | 0.0151 | 0.0133 | 0.0258 | 0.0204 | 0.0208 | 0.0122 | 0.0270 | 0.0190 | 0.9099 | 0.9344 | 0.0036 | 0.2000 | 0.0145 | 0.8000 | 0.0163 | 0.0000 | 0.0435 | 0.0000 | 0.0870 | 0.0000 | 0.1431 | 0.0000 | 0.0833 | 0.0000 | 0.1105 | 0.0000 | 0.4982 | 0.0000 | 0.0019 | 0.0019 | 0.0061 | 0.0129 | 0.0399 | 0.0633 | 0.0672 | 0.0987 | 0.7081 | 5 | 7 | 8 | 9 | 11 | 13 | 15 | 20 | 32 | 0.2512 | 0.44 | 1.751 | 0.7487 | 564.9 | 50306.4 | 9130000 | 2400000000 | 0.5918 | 0.0979 | 0.0534 | 0.0357 | 0.0820 | 0.0510 | 0.0996 | 0.0522 | 0.1245 | 0.0695 | 0.1572 | 0.0948 | 0.1789 | 0.1024 | 0.1727 | 0.1371 | 0.1011 | 0.1779 | 0.0306 | 0.2793 | 0.0244 | 0.0248 | 0.0307 | 0.0322 | 0.0359 | 0.0315 | 0.0432 | 0.0424 | 0.0663 | 0.0619 | 0.0788 | 0.0696 | 0.0772 | 0.0803 | 0.1043 | 0.1080 | 0.5391 | 0.5493 | 0.0219 | 0.0129 | 0.0172 | 0.0233 | 0.0256 | 0.0259 | 0.0339 | 0.0291 | 0.0516 | 0.0505 | 0.0793 | 0.0627 | 0.0652 | 0.0524 | 0.0814 | 0.0996 | 0.6239 | 0.6436 | 0.0286 | 0.0414 | 0.0352 | 0.0447 | 0.0521 | 0.0660 | 0.0663 | 0.1015 | 0.5642 | ||
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 977 | 894 | | 8678 | 22119 | 392.0 | 75.13 | 173.89 | 314.23 | 282 | 322 | 354 | 381 | 401 | 420 | 435 | 453 | 485 | 0.0511 | 1131 | 1.201 | 88.96 | 38.42 | 7 | 0.0282 | 245 | 0.0021 | 9.63 | 6.499 | 0.3468 | 159312.0 | 66800000 | 28800000000 | 12700000000000 | 0.4083 | 0.2246 | 0.0002 | 0.0000 | 0.0025 | 0.0000 | 0.0025 | 0.0001 | 0.0084 | 0.0015 | 0.0256 | 0.0120 | 0.0520 | 0.0300 | 0.0441 | 0.0144 | 0.0689 | 0.0254 | 0.7959 | 0.9166 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0007 | 0.0001 | 0.0032 | 0.0014 | 0.0140 | 0.0107 | 0.0286 | 0.0280 | 0.0184 | 0.0113 | 0.0282 | 0.0210 | 0.9063 | 0.9274 | 0.0066 | 0.0000 | 0.0148 | 0.0000 | 0.0206 | 0.0000 | 0.0378 | 0.0000 | 0.0395 | 0.0000 | 0.0625 | 0.0000 | 0.0740 | 0.0000 | 0.0806 | 0.0000 | 0.6637 | 0.0000 | 0.0015 | 0.0023 | 0.0048 | 0.0094 | 0.0270 | 0.0347 | 0.0425 | 0.0628 | 0.8151 | 8 | 9 | 11 | 13 | 17 | 36 | 101 | 281 | 635 | 0.1573 | 22.71 | 4.082 | 0.6152 | 128970.0 | 132000000 | 157000000000 | 209000000000000 | 0.4818 | 0.1310 | 0.0786 | 0.0027 | 0.1743 | 0.0342 | 0.2141 | 0.1218 | 0.1446 | 0.1207 | 0.1503 | 0.1613 | 0.1230 | 0.1795 | 0.0501 | 0.1111 | 0.0353 | 0.1058 | 0.0296 | 0.1629 | 0.0005 | 0.0002 | 0.0003 | 0.0003 | 0.0018 | 0.0015 | 0.0102 | 0.0083 | 0.0355 | 0.0349 | 0.0697 | 0.0563 | 0.0468 | 0.0443 | 0.0615 | 0.0621 | 0.7736 | 0.7921 | 0.0002 | 0.0008 | 0.0014 | 0.0008 | 0.0024 | 0.0030 | 0.0102 | 0.0095 | 0.0454 | 0.0447 | 0.0733 | 0.0818 | 0.0542 | 0.0653 | 0.0806 | 0.0799 | 0.7323 | 0.7140 | 0.0002 | 0.0013 | 0.0044 | 0.0091 | 0.0417 | 0.0714 | 0.0488 | 0.0701 | 0.7531 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 154 | 245 | | 7441 | 18098 | 595.1 | 99.87 | 158.05 | 276.24 | 459 | 515 | 549 | 576 | 598 | 618 | 640 | 669 | 725 | 0.0530 | 960 | 0.791 | 112.90 | 27.89 | 2 | 0.0372 | 277 | 0.0011 | 26.39 | 7.165 | 0.2288 | 364116.0 | 229000000 | 147000000000 | 96900000000000 | 0.4475 | 0.1984 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0016 | 0.0000 | 0.0053 | 0.0005 | 0.0258 | 0.0124 | 0.0455 | 0.0206 | 0.0458 | 0.0151 | 0.0692 | 0.0230 | 0.8059 | 0.9282 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0003 | 0.0163 | 0.0116 | 0.0267 | 0.0174 | 0.0252 | 0.0115 | 0.0358 | 0.0181 | 0.8938 | 0.9412 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0292 | 0.0000 | 0.0560 | 0.0000 | 0.0840 | 0.0000 | 0.0793 | 0.0000 | 0.1039 | 0.0000 | 0.6196 | 0.0000 | 0.0018 | 0.0036 | 0.0094 | 0.0214 | 0.0420 | 0.0641 | 0.0646 | 0.0876 | 0.7055 | 11 | 14 | 17 | 20 | 25 | 35 | 85 | 239 | 575 | 0.1535 | 16.74 | 4.037 | 0.6476 | 101285.0 | 90600000 | 95000000000 | 112000000000000 | 0.3437 | 0.2785 | 0.0470 | 0.0020 | 0.1678 | 0.0214 | 0.1893 | 0.0935 | 0.1530 | 0.1136 | 0.1732 | 0.1877 | 0.0980 | 0.1717 | 0.0779 | 0.1236 | 0.0671 | 0.1142 | 0.0268 | 0.1723 | 0.0002 | 0.0000 | 0.0008 | 0.0002 | 0.0008 | 0.0013 | 0.0102 | 0.0086 | 0.0376 | 0.0335 | 0.0599 | 0.0539 | 0.0436 | 0.0392 | 0.0626 | 0.0588 | 0.7843 | 0.8046 | 0.0000 | 0.0003 | 0.0012 | 0.0000 | 0.0042 | 0.0040 | 0.0138 | 0.0138 | 0.0413 | 0.0458 | 0.0655 | 0.0684 | 0.0487 | 0.0468 | 0.0667 | 0.0620 | 0.7586 | 0.7589 | 0.0002 | 0.0007 | 0.0023 | 0.0114 | 0.0416 | 0.0654 | 0.0444 | 0.0633 | 0.7707 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 692 | 185 | | 19415 | 44441 | 368.7 | 56.02 | 244.04 | 276.54 | 299 | 324 | 341 | 357 | 370 | 384 | 398 | 414 | 438 | 0.0403 | 1792 | 0.714 | 124.33 | 24.70 | 1 | 0.0157 | 305 | 0.0014 | 22.18 | 6.923 | 0.2357 | 139081.0 | 53500000 | 21000000000 | 8390000000000 | 0.4311 | 0.2269 | 0.0001 | 0.0000 | 0.0008 | 0.0001 | 0.0028 | 0.0001 | 0.0066 | 0.0002 | 0.0259 | 0.0087 | 0.0530 | 0.0182 | 0.0576 | 0.0109 | 0.0865 | 0.0176 | 0.7667 | 0.9443 | 0.0001 | 0.0000 | 0.0004 | 0.0001 | 0.0011 | 0.0001 | 0.0033 | 0.0002 | 0.0141 | 0.0084 | 0.0282 | 0.0172 | 0.0273 | 0.0090 | 0.0375 | 0.0134 | 0.8880 | 0.9517 | 0.0119 | 0.0000 | 0.0209 | 0.0000 | 0.0346 | 0.0000 | 0.0930 | 0.0000 | 0.1169 | 0.0000 | 0.1574 | 0.0000 | 0.1199 | 0.0000 | 0.1306 | 0.0000 | 0.3148 | 0.0000 | 0.0012 | 0.0035 | 0.0100 | 0.0254 | 0.0509 | 0.0848 | 0.0988 | 0.1192 | 0.6061 | 17 | 22 | 30 | 54 | 118 | 220 | 341 | 473 | 647 | 0.0281 | 44.65 | 6.124 | 0.4266 | 136024.0 | 100000000 | 87800000000 | 88300000000000 | 0.4534 | 0.1804 | 0.0700 | 0.0020 | 0.2411 | 0.0134 | 0.3304 | 0.1499 | 0.1469 | 0.1951 | 0.0898 | 0.2149 | 0.0610 | 0.1886 | 0.0354 | 0.0976 | 0.0173 | 0.0724 | 0.0080 | 0.0662 | 0.0003 | 0.0002 | 0.0010 | 0.0004 | 0.0018 | 0.0013 | 0.0092 | 0.0076 | 0.0506 | 0.0416 | 0.1014 | 0.0881 | 0.0667 | 0.0543 | 0.0944 | 0.0803 | 0.6746 | 0.7262 | 0.0007 | 0.0004 | 0.0014 | 0.0017 | 0.0031 | 0.0043 | 0.0147 | 0.0194 | 0.0670 | 0.0789 | 0.1259 | 0.1392 | 0.0883 | 0.0943 | 0.1136 | 0.1275 | 0.5852 | 0.5343 | 0.0001 | 0.0007 | 0.0030 | 0.0105 | 0.0587 | 0.1131 | 0.0775 | 0.1049 | 0.6315 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 125 | 813 | | 4044 | 8852 | 602.6 | 91.52 | 41.19 | 63.75 | 467 | 546 | 581 | 603 | 621 | 637 | 653 | 670 | 697 | 0.0916 | 811 | 0.861 | 103.18 | 25.63 | 4 | 0.0601 | 243 | 0.0019 | 32.85 | 6.649 | 0.2422 | 371488.0 | 233000000 | 149000000000 | 95900000000000 | 0.4344 | 0.2018 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0008 | 0.0262 | 0.0168 | 0.0455 | 0.0300 | 0.0385 | 0.0173 | 0.0691 | 0.0297 | 0.8172 | 0.9055 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0008 | 0.0201 | 0.0167 | 0.0321 | 0.0289 | 0.0201 | 0.0157 | 0.0338 | 0.0282 | 0.8928 | 0.9097 | 0.0279 | 0.0000 | 0.0391 | 0.0000 | 0.0615 | 0.1429 | 0.1006 | 0.2857 | 0.1006 | 0.2857 | 0.1564 | 0.2857 | 0.1229 | 0.0000 | 0.0950 | 0.0000 | 0.2961 | 0.0000 | 0.0008 | 0.0021 | 0.0062 | 0.0181 | 0.0402 | 0.0743 | 0.0812 | 0.0952 | 0.6820 | 9 | 11 | 14 | 16 | 19 | 24 | 32 | 45 | 88 | 0.0559 | 3.74 | 3.856 | 0.6364 | 5760.6 | 1520000 | 505000000 | 191000000000 | 0.4879 | 0.1680 | 0.0222 | 0.0179 | 0.0677 | 0.0335 | 0.0812 | 0.0288 | 0.1141 | 0.0594 | 0.1460 | 0.0957 | 0.1470 | 0.0868 | 0.1692 | 0.1094 | 0.1335 | 0.1627 | 0.1190 | 0.4059 | 0.0058 | 0.0099 | 0.0173 | 0.0192 | 0.0142 | 0.0128 | 0.0242 | 0.0271 | 0.0468 | 0.0434 | 0.0560 | 0.0449 | 0.0629 | 0.0545 | 0.0844 | 0.0813 | 0.6884 | 0.7067 | 0.0032 | 0.0069 | 0.0153 | 0.0122 | 0.0159 | 0.0130 | 0.0312 | 0.0298 | 0.0503 | 0.0519 | 0.0751 | 0.0833 | 0.0649 | 0.0596 | 0.0808 | 0.0795 | 0.6635 | 0.6639 | 0.0049 | 0.0113 | 0.0157 | 0.0300 | 0.0458 | 0.0679 | 0.0684 | 0.0915 | 0.6644 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1217 | 492 | | 4158 | 8748 | 478.3 | 77.87 | 112.81 | 236.09 | 376 | 414 | 441 | 464 | 483 | 499 | 516 | 535 | 574 | 0.0725 | 634 | 0.983 | 79.31 | 27.31 | 1 | 0.0536 | 223 | 0.0016 | 22.49 | 6.757 | 0.2408 | 234837.0 | 118000000 | 60800000000 | 31900000000000 | 0.3975 | 0.2479 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0070 | 0.0005 | 0.0263 | 0.0161 | 0.0444 | 0.0266 | 0.0456 | 0.0159 | 0.0702 | 0.0242 | 0.8058 | 0.9168 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0002 | 0.0174 | 0.0145 | 0.0277 | 0.0252 | 0.0261 | 0.0128 | 0.0397 | 0.0206 | 0.8859 | 0.9267 | 0.0048 | 0.0000 | 0.0048 | 0.0000 | 0.0096 | 0.0556 | 0.0264 | 0.0833 | 0.0769 | 0.1667 | 0.0817 | 0.1389 | 0.1082 | 0.1667 | 0.1034 | 0.1111 | 0.5841 | 0.2778 | 0.0014 | 0.0018 | 0.0063 | 0.0136 | 0.0407 | 0.0678 | 0.0691 | 0.0985 | 0.7010 | 5 | 7 | 8 | 9 | 10 | 12 | 22 | 146 | 413 | 0.1638 | 17.76 | 3.315 | 0.5824 | 68457.9 | 58700000 | 59900000000 | 68200000000000 | 0.3262 | 0.2943 | 0.0588 | 0.0025 | 0.2888 | 0.0296 | 0.2513 | 0.1605 | 0.1016 | 0.1951 | 0.1123 | 0.1975 | 0.0695 | 0.1383 | 0.1016 | 0.0864 | 0.0107 | 0.0963 | 0.0053 | 0.0938 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0005 | 0.0081 | 0.0076 | 0.0389 | 0.0360 | 0.0567 | 0.0536 | 0.0354 | 0.0337 | 0.0445 | 0.0469 | 0.8164 | 0.8208 | 0.0006 | 0.0006 | 0.0000 | 0.0012 | 0.0045 | 0.0041 | 0.0078 | 0.0088 | 0.0380 | 0.0364 | 0.0553 | 0.0634 | 0.0330 | 0.0346 | 0.0508 | 0.0511 | 0.8101 | 0.7999 | 0.0000 | 0.0000 | 0.0005 | 0.0123 | 0.0410 | 0.0511 | 0.0373 | 0.0453 | 0.8125 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 817 | | 5202 | 13328 | 498.6 | 85.62 | 75.42 | 193.51 | 376 | 424 | 460 | 483 | 503 | 525 | 551 | 573 | 600 | 0.0606 | 808 | 0.924 | 121.38 | 32.28 | 1 | 0.0600 | 312 | 0.0016 | 14.59 | 6.726 | 0.2939 | 255905.0 | 135000000 | 72700000000 | 40000000000000 | 0.4179 | 0.2243 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0023 | 0.0002 | 0.0100 | 0.0010 | 0.0267 | 0.0117 | 0.0460 | 0.0271 | 0.0409 | 0.0125 | 0.0779 | 0.0230 | 0.7949 | 0.9246 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0041 | 0.0008 | 0.0129 | 0.0112 | 0.0226 | 0.0247 | 0.0142 | 0.0106 | 0.0293 | 0.0185 | 0.9158 | 0.9342 | 0.0074 | 0.0227 | 0.0185 | 0.0000 | 0.0444 | 0.0455 | 0.0628 | 0.0455 | 0.0795 | 0.1591 | 0.1109 | 0.1364 | 0.1146 | 0.1136 | 0.1109 | 0.1364 | 0.4510 | 0.3409 | 0.0022 | 0.0041 | 0.0081 | 0.0144 | 0.0276 | 0.0398 | 0.0446 | 0.0692 | 0.7901 | 8 | 10 | 11 | 12 | 14 | 17 | 27 | 59 | 186 | 0.2830 | 9.88 | 2.941 | 0.7317 | 43131.2 | 46900000 | 63500000000 | 95400000000000 | 0.3571 | 0.2342 | 0.0717 | 0.0047 | 0.2131 | 0.0292 | 0.2384 | 0.1318 | 0.1751 | 0.1111 | 0.1245 | 0.1770 | 0.0802 | 0.2062 | 0.0422 | 0.1234 | 0.0295 | 0.1036 | 0.0253 | 0.1130 | 0.0008 | 0.0003 | 0.0011 | 0.0036 | 0.0019 | 0.0062 | 0.0121 | 0.0147 | 0.0524 | 0.0421 | 0.0746 | 0.0718 | 0.0543 | 0.0492 | 0.0758 | 0.0744 | 0.7271 | 0.7378 | 0.0000 | 0.0005 | 0.0009 | 0.0010 | 0.0023 | 0.0025 | 0.0138 | 0.0125 | 0.0555 | 0.0609 | 0.0909 | 0.0973 | 0.0564 | 0.0579 | 0.0844 | 0.0868 | 0.6957 | 0.6806 | 0.0004 | 0.0017 | 0.0008 | 0.0138 | 0.0522 | 0.0823 | 0.0547 | 0.0852 | 0.7090 | ||
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 708 | 397 | | 15447 | 27394 | 562.4 | 113.78 | 118.30 | 212.73 | 394 | 458 | 507 | 542 | 576 | 606 | 636 | 667 | 703 | 0.0495 | 1356 | 0.896 | 108.19 | 30.00 | 3 | 0.0188 | 291 | 0.0006 | 29.72 | 7.605 | 0.2191 | 329218.0 | 199000000 | 124000000000 | 78600000000000 | 0.3988 | 0.2308 | 0.0014 | 0.0000 | 0.0019 | 0.0001 | 0.0040 | 0.0004 | 0.0105 | 0.0011 | 0.0269 | 0.0087 | 0.0473 | 0.0169 | 0.0485 | 0.0102 | 0.0672 | 0.0157 | 0.7922 | 0.9469 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0001 | 0.0023 | 0.0010 | 0.0107 | 0.0080 | 0.0188 | 0.0166 | 0.0160 | 0.0091 | 0.0204 | 0.0143 | 0.9310 | 0.9510 | 0.0029 | 0.0000 | 0.0095 | 0.0179 | 0.0147 | 0.0536 | 0.0297 | 0.1607 | 0.0612 | 0.1250 | 0.0718 | 0.1071 | 0.0872 | 0.2500 | 0.1213 | 0.1071 | 0.6015 | 0.1786 | 0.0008 | 0.0010 | 0.0032 | 0.0069 | 0.0226 | 0.0401 | 0.0411 | 0.0534 | 0.8309 | 7 | 9 | 10 | 11 | 12 | 15 | 40 | 206 | 467 | 0.3132 | 20.18 | 3.462 | 0.7115 | 59247.2 | 38200000 | 27600000000 | 21600000000000 | 0.5023 | 0.1444 | 0.0436 | 0.0036 | 0.1336 | 0.0128 | 0.2377 | 0.1026 | 0.1744 | 0.1354 | 0.1547 | 0.1810 | 0.1069 | 0.1882 | 0.0675 | 0.1055 | 0.0520 | 0.1119 | 0.0295 | 0.1589 | 0.0000 | 0.0003 | 0.0003 | 0.0004 | 0.0010 | 0.0004 | 0.0058 | 0.0038 | 0.0203 | 0.0189 | 0.0418 | 0.0353 | 0.0301 | 0.0220 | 0.0517 | 0.0418 | 0.8491 | 0.8771 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0058 | 0.0079 | 0.0263 | 0.0302 | 0.0558 | 0.0631 | 0.0452 | 0.0492 | 0.0622 | 0.0705 | 0.8037 | 0.7782 | 0.0000 | 0.0000 | 0.0006 | 0.0049 | 0.0263 | 0.0486 | 0.0405 | 0.0571 | 0.8221 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 828 | 731 | | 4916 | 17078 | 344.5 | 49.98 | 70.06 | 109.17 | 278 | 302 | 316 | 330 | 344 | 358 | 374 | 391 | 410 | 0.0440 | 752 | 0.700 | 121.80 | 29.61 | 2 | 0.0728 | 358 | 0.0032 | 8.09 | 6.021 | 0.3596 | 121208.0 | 43500000 | 15900000000 | 5900000000000 | 0.4249 | 0.2173 | 0.0002 | 0.0000 | 0.0015 | 0.0000 | 0.0045 | 0.0000 | 0.0067 | 0.0000 | 0.0270 | 0.0128 | 0.0399 | 0.0214 | 0.0394 | 0.0128 | 0.0789 | 0.0218 | 0.8018 | 0.9312 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0027 | 0.0000 | 0.0144 | 0.0128 | 0.0229 | 0.0214 | 0.0200 | 0.0128 | 0.0328 | 0.0185 | 0.9062 | 0.9345 | 0.0187 | 1.0000 | 0.0258 | 0.0000 | 0.0328 | 0.0000 | 0.0562 | 0.0000 | 0.1007 | 0.0000 | 0.1499 | 0.0000 | 0.1288 | 0.0000 | 0.1241 | 0.0000 | 0.3630 | 0.0000 | 0.0021 | 0.0041 | 0.0062 | 0.0144 | 0.0299 | 0.0533 | 0.0545 | 0.0685 | 0.7671 | 6 | 8 | 10 | 11 | 14 | 26 | 60 | 123 | 221 | 0.1196 | 5.30 | 3.437 | 0.5812 | 16825.5 | 6090000 | 2810000000 | 1590000000000 | 0.3847 | 0.2364 | 0.0327 | 0.0062 | 0.1401 | 0.0166 | 0.2424 | 0.0916 | 0.2139 | 0.1211 | 0.1718 | 0.1868 | 0.1149 | 0.2002 | 0.0516 | 0.1454 | 0.0263 | 0.1174 | 0.0063 | 0.1148 | 0.0000 | 0.0005 | 0.0006 | 0.0010 | 0.0023 | 0.0019 | 0.0083 | 0.0103 | 0.0391 | 0.0317 | 0.0712 | 0.0567 | 0.0463 | 0.0437 | 0.0805 | 0.0695 | 0.7518 | 0.7849 | 0.0000 | 0.0000 | 0.0009 | 0.0013 | 0.0021 | 0.0033 | 0.0145 | 0.0170 | 0.0532 | 0.0625 | 0.0907 | 0.0938 | 0.0628 | 0.0780 | 0.0937 | 0.1001 | 0.6822 | 0.6441 | 0.0004 | 0.0002 | 0.0032 | 0.0122 | 0.0464 | 0.0780 | 0.0622 | 0.0900 | 0.7075 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 980 | 154 | | 9107 | 15265 | 478.7 | 85.92 | 198.56 | 276.33 | 358 | 401 | 437 | 463 | 485 | 506 | 527 | 552 | 588 | 0.0735 | 1122 | 0.982 | 84.40 | 29.43 | 4 | 0.0254 | 231 | 0.0010 | 22.23 | 7.221 | 0.2396 | 236580.0 | 120000000 | 62600000000 | 33300000000000 | 0.4434 | 0.2060 | 0.0008 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0001 | 0.0113 | 0.0006 | 0.0270 | 0.0119 | 0.0415 | 0.0194 | 0.0463 | 0.0139 | 0.0694 | 0.0222 | 0.7980 | 0.9319 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0012 | 0.0000 | 0.0040 | 0.0006 | 0.0131 | 0.0117 | 0.0209 | 0.0179 | 0.0208 | 0.0114 | 0.0297 | 0.0180 | 0.9101 | 0.9405 | 0.0083 | 0.0294 | 0.0173 | 0.0588 | 0.0273 | 0.0882 | 0.0380 | 0.2059 | 0.0512 | 0.2353 | 0.0760 | 0.1471 | 0.0950 | 0.1471 | 0.1230 | 0.0588 | 0.5640 | 0.0294 | 0.0010 | 0.0031 | 0.0072 | 0.0149 | 0.0256 | 0.0345 | 0.0450 | 0.0565 | 0.8122 | 11 | 14 | 19 | 34 | 73 | 133 | 224 | 349 | 565 | 0.0491 | 47.73 | 5.568 | 0.4783 | 115779.0 | 101000000 | 112000000000 | 147000000000000 | 0.3844 | 0.2395 | 0.0410 | 0.0015 | 0.1640 | 0.0173 | 0.2243 | 0.0857 | 0.1640 | 0.1357 | 0.1446 | 0.1765 | 0.1106 | 0.1922 | 0.0789 | 0.1361 | 0.0472 | 0.1023 | 0.0255 | 0.1526 | 0.0004 | 0.0003 | 0.0011 | 0.0014 | 0.0023 | 0.0048 | 0.0151 | 0.0114 | 0.0519 | 0.0457 | 0.0774 | 0.0628 | 0.0614 | 0.0517 | 0.0854 | 0.0750 | 0.7052 | 0.7469 | 0.0002 | 0.0005 | 0.0018 | 0.0031 | 0.0067 | 0.0089 | 0.0220 | 0.0270 | 0.0687 | 0.0786 | 0.1061 | 0.1226 | 0.0859 | 0.0881 | 0.1079 | 0.1098 | 0.6006 | 0.5613 | 0.0004 | 0.0012 | 0.0052 | 0.0181 | 0.0596 | 0.0890 | 0.0721 | 0.1031 | 0.6512 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 372 | 900 | | 5044 | 9324 | 570.5 | 98.09 | 110.30 | 193.81 | 423 | 504 | 548 | 574 | 591 | 608 | 625 | 644 | 675 | 0.0741 | 691 | 0.949 | 144.16 | 41.87 | 3 | 0.0765 | 386 | 0.0009 | 58.08 | 7.313 | 0.1858 | 335121.0 | 201000000 | 123000000000 | 76200000000000 | 0.4530 | 0.1918 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0002 | 0.0055 | 0.0012 | 0.0271 | 0.0139 | 0.0472 | 0.0212 | 0.0462 | 0.0133 | 0.0650 | 0.0234 | 0.8066 | 0.9268 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0018 | 0.0012 | 0.0148 | 0.0139 | 0.0237 | 0.0212 | 0.0189 | 0.0133 | 0.0283 | 0.0218 | 0.9121 | 0.9285 | 0.0051 | 1.0000 | 0.0204 | 0.0000 | 0.0382 | 0.0000 | 0.0789 | 0.0000 | 0.1399 | 0.0000 | 0.1527 | 0.0000 | 0.1425 | 0.0000 | 0.1552 | 0.0000 | 0.2672 | 0.0000 | 0.0006 | 0.0016 | 0.0039 | 0.0132 | 0.0319 | 0.0631 | 0.0673 | 0.0879 | 0.7304 | 13 | 15 | 17 | 20 | 24 | 37 | 65 | 143 | 347 | 0.2499 | 4.68 | 3.068 | 0.7533 | 49725.0 | 35000000 | 30000000000 | 29200000000000 | 0.6863 | 0.0611 | 0.0201 | 0.0070 | 0.0828 | 0.0120 | 0.2081 | 0.0468 | 0.1834 | 0.0807 | 0.1969 | 0.1723 | 0.1454 | 0.1912 | 0.0805 | 0.1524 | 0.0403 | 0.1404 | 0.0425 | 0.1972 | 0.0004 | 0.0022 | 0.0004 | 0.0022 | 0.0021 | 0.0065 | 0.0116 | 0.0151 | 0.0418 | 0.0391 | 0.0708 | 0.0613 | 0.0472 | 0.0459 | 0.0911 | 0.0911 | 0.7345 | 0.7368 | 0.0000 | 0.0006 | 0.0005 | 0.0006 | 0.0051 | 0.0011 | 0.0142 | 0.0146 | 0.0524 | 0.0611 | 0.0956 | 0.0952 | 0.0478 | 0.0538 | 0.0935 | 0.0947 | 0.6909 | 0.6784 | 0.0000 | 0.0000 | 0.0019 | 0.0116 | 0.0551 | 0.0811 | 0.0487 | 0.0982 | 0.7034 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 165 | 346 | | 2161 | 4173 | 394.6 | 54.04 | 116.71 | 168.59 | 331 | 354 | 368 | 382 | 402 | 418 | 431 | 442 | 455 | 0.1006 | 420 | 1.034 | 84.17 | 27.73 | 4 | 0.0995 | 215 | 0.0035 | 8.75 | 5.908 | 0.3537 | 158617.0 | 64700000 | 26800000000 | 11200000000000 | 0.4254 | 0.2146 | 0.0000 | 0.0000 | 0.0005 | 0.0005 | 0.0025 | 0.0000 | 0.0051 | 0.0028 | 0.0275 | 0.0151 | 0.0499 | 0.0420 | 0.0403 | 0.0193 | 0.0780 | 0.0297 | 0.7961 | 0.8906 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0010 | 0.0000 | 0.0025 | 0.0028 | 0.0218 | 0.0151 | 0.0412 | 0.0420 | 0.0233 | 0.0193 | 0.0377 | 0.0297 | 0.8724 | 0.8906 | 0.0962 | 0.0000 | 0.2115 | 0.0000 | 0.2115 | 0.0000 | 0.1346 | 0.0000 | 0.1731 | 0.0000 | 0.0962 | 0.0000 | 0.0577 | 0.0000 | 0.0192 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0034 | 0.0034 | 0.0145 | 0.0298 | 0.0375 | 0.0486 | 0.0520 | 0.8090 | 14 | 17 | 20 | 25 | 38 | 61 | 108 | 180 | 346 | 0.1096 | 12.03 | 4.053 | 0.6346 | 42038.0 | 22900000 | 14900000000 | 10800000000000 | 0.3901 | 0.2553 | 0.0117 | 0.0015 | 0.0731 | 0.0030 | 0.2251 | 0.0345 | 0.1842 | 0.0811 | 0.1754 | 0.1532 | 0.1023 | 0.2387 | 0.0877 | 0.1517 | 0.0614 | 0.1276 | 0.0789 | 0.2087 | 0.0000 | 0.0006 | 0.0015 | 0.0000 | 0.0037 | 0.0019 | 0.0110 | 0.0146 | 0.0389 | 0.0285 | 0.0946 | 0.0856 | 0.0484 | 0.0463 | 0.0748 | 0.0533 | 0.7273 | 0.7692 | 0.0000 | 0.0000 | 0.0029 | 0.0022 | 0.0039 | 0.0011 | 0.0157 | 0.0176 | 0.0695 | 0.0812 | 0.1282 | 0.1405 | 0.0744 | 0.0768 | 0.1018 | 0.1098 | 0.6037 | 0.5708 | 0.0000 | 0.0017 | 0.0042 | 0.0135 | 0.0581 | 0.1053 | 0.0699 | 0.1003 | 0.6470 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 655 | 519 | | 12431 | 24620 | 390.0 | 70.08 | 73.02 | 145.52 | 287 | 322 | 350 | 376 | 398 | 418 | 437 | 454 | 476 | 0.0531 | 1307 | 0.717 | 116.71 | 35.11 | 3 | 0.0323 | 401 | 0.0014 | 13.24 | 6.814 | 0.3028 | 157023.0 | 65000000 | 27500000000 | 11900000000000 | 0.4378 | 0.1981 | 0.0007 | 0.0000 | 0.0029 | 0.0000 | 0.0055 | 0.0000 | 0.0115 | 0.0009 | 0.0276 | 0.0098 | 0.0447 | 0.0175 | 0.0492 | 0.0111 | 0.0732 | 0.0171 | 0.7847 | 0.9436 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0000 | 0.0037 | 0.0009 | 0.0122 | 0.0098 | 0.0195 | 0.0175 | 0.0178 | 0.0105 | 0.0271 | 0.0152 | 0.9168 | 0.9461 | 0.0102 | 1.0000 | 0.0215 | 0.0000 | 0.0269 | 0.0000 | 0.0449 | 0.0000 | 0.0682 | 0.0000 | 0.0922 | 0.0000 | 0.0999 | 0.0000 | 0.1191 | 0.0000 | 0.5171 | 0.0000 | 0.0007 | 0.0036 | 0.0042 | 0.0104 | 0.0227 | 0.0348 | 0.0407 | 0.0547 | 0.8282 | 8 | 10 | 11 | 13 | 15 | 20 | 33 | 82 | 218 | 0.1379 | 2.58 | 2.741 | 0.6004 | 26508.4 | 16200000 | 12600000000 | 11400000000000 | 0.6289 | 0.0769 | 0.0413 | 0.0027 | 0.1013 | 0.0182 | 0.1888 | 0.0633 | 0.1750 | 0.0919 | 0.1721 | 0.1461 | 0.1327 | 0.1875 | 0.1013 | 0.1379 | 0.0560 | 0.1347 | 0.0315 | 0.2176 | 0.0002 | 0.0005 | 0.0007 | 0.0006 | 0.0016 | 0.0015 | 0.0123 | 0.0101 | 0.0446 | 0.0428 | 0.0768 | 0.0683 | 0.0519 | 0.0466 | 0.0718 | 0.0703 | 0.7402 | 0.7592 | 0.0004 | 0.0009 | 0.0008 | 0.0018 | 0.0023 | 0.0018 | 0.0159 | 0.0140 | 0.0529 | 0.0605 | 0.0898 | 0.0918 | 0.0567 | 0.0628 | 0.0814 | 0.0868 | 0.6997 | 0.6794 | 0.0004 | 0.0000 | 0.0015 | 0.0114 | 0.0529 | 0.0806 | 0.0550 | 0.0825 | 0.7157 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 968 | 293 | | 9056 | 13099 | 516.1 | 88.24 | 114.69 | 251.28 | 396 | 459 | 491 | 512 | 529 | 545 | 562 | 583 | 612 | 0.0837 | 1097 | 0.940 | 103.45 | 28.16 | 6 | 0.0282 | 255 | 0.0009 | 51.99 | 7.361 | 0.1986 | 274112.0 | 149000000 | 82200000000 | 46100000000000 | 0.4370 | 0.2059 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0050 | 0.0007 | 0.0278 | 0.0152 | 0.0543 | 0.0277 | 0.0482 | 0.0150 | 0.0760 | 0.0288 | 0.7879 | 0.9127 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0007 | 0.0168 | 0.0152 | 0.0317 | 0.0272 | 0.0203 | 0.0143 | 0.0351 | 0.0258 | 0.8942 | 0.9168 | 0.0106 | 0.0000 | 0.0080 | 0.0000 | 0.0359 | 0.0000 | 0.0638 | 0.0000 | 0.1237 | 0.0000 | 0.1463 | 0.0000 | 0.1077 | 0.0000 | 0.1303 | 0.0000 | 0.3737 | 0.0000 | 0.0015 | 0.0017 | 0.0063 | 0.0160 | 0.0428 | 0.0699 | 0.0713 | 0.1070 | 0.6836 | 8 | 10 | 12 | 14 | 20 | 34 | 63 | 120 | 305 | 0.0778 | 7.79 | 3.212 | 0.5546 | 76290.7 | 93700000 | 170000000000 | 429000000000000 | 0.7394 | 0.0357 | 0.0196 | 0.0006 | 0.0825 | 0.0106 | 0.1649 | 0.0417 | 0.1872 | 0.0636 | 0.1702 | 0.1514 | 0.1584 | 0.2125 | 0.1152 | 0.1383 | 0.0654 | 0.1383 | 0.0366 | 0.2430 | 0.0003 | 0.0000 | 0.0019 | 0.0013 | 0.0083 | 0.0037 | 0.0156 | 0.0088 | 0.0568 | 0.0470 | 0.0879 | 0.0948 | 0.0632 | 0.0564 | 0.0959 | 0.0866 | 0.6702 | 0.7013 | 0.0008 | 0.0005 | 0.0004 | 0.0014 | 0.0059 | 0.0028 | 0.0184 | 0.0229 | 0.0675 | 0.0744 | 0.1010 | 0.1155 | 0.0700 | 0.0734 | 0.1014 | 0.1001 | 0.6345 | 0.6090 | 0.0015 | 0.0018 | 0.0041 | 0.0170 | 0.0595 | 0.0983 | 0.0698 | 0.0953 | 0.6526 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 512 | 618 | | 11255 | 20255 | 428.2 | 87.05 | 105.63 | 203.30 | 309 | 354 | 384 | 408 | 429 | 449 | 474 | 501 | 549 | 0.0544 | 1102 | 0.683 | 111.73 | 25.46 | 6 | 0.0275 | 310 | 0.0009 | 22.99 | 7.263 | 0.2438 | 190902.0 | 88200000 | 42000000000 | 20600000000000 | 0.4424 | 0.2031 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0026 | 0.0004 | 0.0084 | 0.0012 | 0.0280 | 0.0134 | 0.0584 | 0.0238 | 0.0474 | 0.0178 | 0.0713 | 0.0278 | 0.7829 | 0.9155 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0033 | 0.0008 | 0.0135 | 0.0104 | 0.0281 | 0.0209 | 0.0204 | 0.0124 | 0.0313 | 0.0184 | 0.9022 | 0.9370 | 0.0011 | 0.0000 | 0.0063 | 0.0000 | 0.0110 | 0.0000 | 0.0226 | 0.0000 | 0.0479 | 0.0000 | 0.0805 | 0.0000 | 0.0642 | 0.0000 | 0.0789 | 0.0000 | 0.6875 | 0.0000 | 0.0009 | 0.0019 | 0.0058 | 0.0140 | 0.0333 | 0.0539 | 0.0552 | 0.0744 | 0.7606 | 8 | 9 | 10 | 11 | 13 | 16 | 42 | 145 | 378 | 0.0720 | 5.26 | 3.153 | 0.4465 | 52486.1 | 36900000 | 30400000000 | 27900000000000 | 0.5667 | 0.1091 | 0.0648 | 0.0042 | 0.2221 | 0.0305 | 0.2455 | 0.1491 | 0.1821 | 0.1574 | 0.1255 | 0.1533 | 0.0690 | 0.1678 | 0.0331 | 0.1262 | 0.0317 | 0.0846 | 0.0262 | 0.1269 | 0.0004 | 0.0000 | 0.0006 | 0.0006 | 0.0010 | 0.0017 | 0.0112 | 0.0092 | 0.0467 | 0.0430 | 0.0696 | 0.0628 | 0.0485 | 0.0415 | 0.0752 | 0.0685 | 0.7467 | 0.7729 | 0.0005 | 0.0005 | 0.0007 | 0.0007 | 0.0016 | 0.0025 | 0.0113 | 0.0152 | 0.0565 | 0.0539 | 0.0774 | 0.0786 | 0.0493 | 0.0607 | 0.0870 | 0.0851 | 0.7156 | 0.7027 | 0.0007 | 0.0000 | 0.0020 | 0.0119 | 0.0543 | 0.0701 | 0.0508 | 0.0795 | 0.7308 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 740 | 703 | | 8862 | 18824 | 530.1 | 80.43 | 114.15 | 251.56 | 421 | 467 | 496 | 517 | 535 | 553 | 573 | 598 | 631 | 0.0548 | 1032 | 0.545 | 114.22 | 22.67 | 5 | 0.0372 | 330 | 0.0009 | 38.41 | 7.314 | 0.2073 | 287452.0 | 159000000 | 89500000000 | 51200000000000 | 0.4491 | 0.2025 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0007 | 0.0001 | 0.0056 | 0.0007 | 0.0282 | 0.0139 | 0.0564 | 0.0200 | 0.0512 | 0.0144 | 0.0715 | 0.0211 | 0.7858 | 0.9298 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0016 | 0.0007 | 0.0179 | 0.0139 | 0.0306 | 0.0200 | 0.0252 | 0.0144 | 0.0335 | 0.0202 | 0.8913 | 0.9307 | 0.0075 | 1.0000 | 0.0188 | 0.0000 | 0.0225 | 0.0000 | 0.0476 | 0.0000 | 0.1164 | 0.0000 | 0.1640 | 0.0000 | 0.1014 | 0.0000 | 0.1502 | 0.0000 | 0.3717 | 0.0000 | 0.0006 | 0.0036 | 0.0074 | 0.0181 | 0.0434 | 0.0613 | 0.0734 | 0.0863 | 0.7059 | 9 | 10 | 12 | 13 | 15 | 20 | 38 | 121 | 352 | 0.1429 | 9.00 | 3.049 | 0.5952 | 76308.2 | 79500000 | 99600000000 | 139000000000000 | 0.5235 | 0.1294 | 0.0259 | 0.0023 | 0.0761 | 0.0164 | 0.2120 | 0.0561 | 0.1942 | 0.0865 | 0.2006 | 0.1645 | 0.1003 | 0.2050 | 0.1036 | 0.1458 | 0.0631 | 0.1341 | 0.0243 | 0.1894 | 0.0000 | 0.0004 | 0.0002 | 0.0004 | 0.0012 | 0.0011 | 0.0067 | 0.0072 | 0.0396 | 0.0383 | 0.0538 | 0.0475 | 0.0401 | 0.0385 | 0.0569 | 0.0591 | 0.8015 | 0.8073 | 0.0003 | 0.0000 | 0.0006 | 0.0006 | 0.0017 | 0.0021 | 0.0056 | 0.0079 | 0.0476 | 0.0539 | 0.0673 | 0.0667 | 0.0437 | 0.0521 | 0.0707 | 0.0758 | 0.7625 | 0.7409 | 0.0000 | 0.0005 | 0.0016 | 0.0065 | 0.0428 | 0.0586 | 0.0418 | 0.0664 | 0.7819 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 489 | 816 | | 9613 | 19666 | 390.1 | 60.27 | 175.40 | 251.54 | 316 | 341 | 358 | 372 | 386 | 400 | 417 | 439 | 471 | 0.0499 | 981 | 1.140 | 113.53 | 39.96 | 1 | 0.0287 | 276 | 0.0011 | 38.49 | 7.151 | 0.1882 | 155802.0 | 63700000 | 26600000000 | 11400000000000 | 0.4343 | 0.2166 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0063 | 0.0003 | 0.0283 | 0.0097 | 0.0643 | 0.0203 | 0.0756 | 0.0131 | 0.1055 | 0.0246 | 0.7186 | 0.9320 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0028 | 0.0001 | 0.0131 | 0.0084 | 0.0304 | 0.0170 | 0.0306 | 0.0084 | 0.0456 | 0.0152 | 0.8770 | 0.9508 | 0.0087 | 0.0000 | 0.0135 | 0.0000 | 0.0279 | 0.0000 | 0.0983 | 0.0000 | 0.1387 | 0.0000 | 0.1513 | 0.0000 | 0.1416 | 0.0000 | 0.1262 | 0.0000 | 0.2938 | 0.0000 | 0.0011 | 0.0035 | 0.0104 | 0.0298 | 0.0782 | 0.1108 | 0.1017 | 0.1210 | 0.5436 | 14 | 16 | 20 | 33 | 69 | 120 | 189 | 295 | 474 | 0.0394 | 31.15 | 5.368 | 0.5068 | 94034.5 | 84100000 | 103000000000 | 154000000000000 | 0.3897 | 0.2589 | 0.0213 | 0.0011 | 0.1385 | 0.0082 | 0.2420 | 0.0616 | 0.1776 | 0.1065 | 0.1672 | 0.1616 | 0.1236 | 0.1947 | 0.0759 | 0.1312 | 0.0374 | 0.1260 | 0.0167 | 0.2092 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0018 | 0.0009 | 0.0087 | 0.0075 | 0.0520 | 0.0374 | 0.0873 | 0.0660 | 0.0601 | 0.0490 | 0.0912 | 0.0703 | 0.6988 | 0.7683 | 0.0002 | 0.0002 | 0.0016 | 0.0006 | 0.0035 | 0.0034 | 0.0199 | 0.0226 | 0.0723 | 0.0866 | 0.1159 | 0.1289 | 0.0783 | 0.0860 | 0.1143 | 0.1210 | 0.5940 | 0.5507 | 0.0000 | 0.0008 | 0.0022 | 0.0144 | 0.0633 | 0.0998 | 0.0700 | 0.1025 | 0.6469 |