High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
SK-BR-3 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 770 194 image if available 4106 14842 217.4 110.14 102.63 168.85 87 104 124 149 193 255 309 338 368 0.0595 883 0.734 130.10 25.02 4 0.0774 318 0.0016 20.13 6.862 0.2708 59394.7
18600000
6250000000
2190000000000
0.3003 0.3143 0.0017 0.0020 0.0017 0.0047 0.0050 0.0027 0.0199 0.0182 0.1393 0.0532 0.2703 0.1097 0.1294 0.0787 0.1592 0.1016 0.2736 0.6292 0.0000 0.0004 0.0000 0.0011 0.0005 0.0007 0.0014 0.0043 0.0199 0.0180 0.0398 0.0371 0.0172 0.0213 0.0330 0.0317 0.8883 0.8853 0.0000 0.0000 0.0000 0.0023 0.0019 0.0023 0.0025 0.0070 0.0243 0.0319 0.0473 0.0474 0.0230 0.0365 0.0398 0.0629 0.8613 0.8096 0.0000 0.0000 0.0010 0.0047 0.0210 0.0367 0.0257 0.0352 0.8756 12 15 18 23 35 53 82 137 279 0.0621 16.73 4.450 0.6158 39039.8
25800000
21500000000
20400000000000
0.5806 0.1178 0.0142 0.0012 0.0745 0.0050 0.1347 0.0255 0.1665 0.0751 0.1808 0.1211 0.1548 0.1645 0.1163 0.1413 0.0879 0.1463 0.0703 0.3200 0.0004 0.0002 0.0022 0.0006 0.0034 0.0017 0.0117 0.0140 0.0549 0.0436 0.0904 0.0624 0.0616 0.0618 0.0940 0.0822 0.6814 0.7336 0.0000 0.0000 0.0015 0.0028 0.0065 0.0070 0.0175 0.0228 0.0713 0.0831 0.1208 0.1189 0.0799 0.0856 0.1097 0.1140 0.5927 0.5658 0.0008 0.0024 0.0040 0.0129 0.0630 0.1018 0.0691 0.1036 0.6424
SK-BR-3
0
DRAQ5 1 TMRE 2 2 2 1 927 522 image if available 3614 6289 297.5 144.28 59.44 77.60 127 157 192 233 266 305 406 465 511 0.1040 654 1.229 109.25 47.52 2 0.0819 296 0.0028 6.07 6.131 0.4083 109347.0
45800000
20700000000
9820000000000
0.3640 0.2549 0.0012 0.0000 0.0012 0.0006 0.0036 0.0025 0.0324 0.0086 0.1032 0.0531 0.1429 0.0834 0.1273 0.0562 0.1020 0.0828 0.4862 0.7128 0.0005 0.0000 0.0005 0.0004 0.0005 0.0015 0.0076 0.0030 0.0219 0.0203 0.0343 0.0263 0.0281 0.0192 0.0357 0.0312 0.8710 0.8980 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0016 0.0039 0.0331 0.0347 0.0410 0.0597 0.0316 0.0414 0.0458 0.0462 0.8469 0.8141 0.0020 0.0013 0.0027 0.0054 0.0229 0.0404 0.0242 0.0310 0.8700 8 11 14 19 26 38 58 92 162 0.0962 2.42 3.459 0.6933 9553.8
2410000
755000000
271000000000
0.5400 0.1318 0.0018 0.0033 0.0126 0.0122 0.0650 0.0236 0.1733 0.0447 0.2365 0.0943 0.2166 0.1561 0.1480 0.1423 0.1137 0.1740 0.0325 0.3496 0.0000 0.0015 0.0005 0.0034 0.0032 0.0076 0.0142 0.0125 0.0500 0.0386 0.0866 0.0773 0.0596 0.0583 0.0830 0.0735 0.7030 0.7273 0.0000 0.0000 0.0012 0.0014 0.0037 0.0064 0.0197 0.0227 0.0614 0.0716 0.1020 0.1106 0.0694 0.0738 0.0860 0.0865 0.6566 0.6270 0.0011 0.0027 0.0043 0.0160 0.0543 0.1005 0.0660 0.0787 0.6766
MDA-MB-231 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 469 438 image if available 2983 6904 291.5 155.73 25.80 36.51 163 179 192 210 232 259 292 423 579 0.1047 723 0.563 78.24 21.26 5 0.0865 258 0.0031 12.41 6.310 0.3653 109220.0
50500000
26800000000
15300000000000
0.4115 0.2245 0.0013 0.0000 0.0013 0.0011 0.0053 0.0049 0.0279 0.0152 0.0810 0.0455 0.1514 0.0829 0.1142 0.0650 0.1116 0.0861 0.5060 0.6994 0.0007 0.0000 0.0007 0.0008 0.0027 0.0036 0.0129 0.0101 0.0278 0.0283 0.0394 0.0449 0.0455 0.0377 0.0502 0.0494 0.8201 0.8251 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0042 0.0048 0.0250 0.0353 0.0722 0.0609 0.0222 0.0304 0.0431 0.0529 0.8333 0.8157 0.0000 0.0022 0.0078 0.0100 0.0288 0.0654 0.0310 0.0488 0.8060 7 9 10 12 14 17 22 30 49 0.1051 1.66 3.110 0.7374 1998.1
320182
69200000
17600000000
0.5249 0.1326 0.0229 0.0158 0.0439 0.0273 0.0768 0.0379 0.1286 0.0532 0.1655 0.0873 0.1864 0.1237 0.1685 0.1324 0.1256 0.1938 0.0818 0.3285 0.0053 0.0100 0.0107 0.0158 0.0191 0.0197 0.0364 0.0262 0.0631 0.0494 0.1039 0.0862 0.0795 0.0733 0.0955 0.1172 0.5866 0.6021 0.0056 0.0129 0.0104 0.0069 0.0288 0.0247 0.0400 0.0366 0.0737 0.0791 0.1017 0.1098 0.0745 0.0692 0.1129 0.0930 0.5524 0.5678 0.0070 0.0152 0.0275 0.0427 0.0719 0.1029 0.0830 0.0918 0.5582
MDA-MB-231 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 632 365 image if available 4889 13256 383.0 256.14 34.30 57.66 183 197 211 228 257 316 420 590 842 0.0671 890 0.504 95.59 26.87 10 0.0714 349 0.0027 26.56 6.768 0.3301 212277.0
153000000
126000000000
111000000000000
0.4295 0.1988 0.0014 0.0022 0.0000 0.0011 0.0177 0.0092 0.0477 0.0152 0.1376 0.0656 0.2030 0.1062 0.1444 0.0846 0.1253 0.1084 0.3229 0.6076 0.0000 0.0014 0.0000 0.0007 0.0010 0.0058 0.0030 0.0093 0.0272 0.0319 0.0495 0.0436 0.0302 0.0367 0.0475 0.0480 0.8417 0.8226 0.0000 0.0019 0.0000 0.0000 0.0039 0.0000 0.0070 0.0056 0.0396 0.0318 0.0591 0.0589 0.0311 0.0308 0.0521 0.0421 0.8073 0.8290 0.0000 0.0000 0.0000 0.0055 0.0325 0.0644 0.0319 0.0576 0.8081 6 7 9 11 13 17 25 40 85 0.1143 7.18 3.518 0.6992 4501.5
1130000
367000000
138000000000
0.5010 0.1794 0.0284 0.0102 0.0869 0.0191 0.1446 0.0339 0.1683 0.0750 0.1629 0.1280 0.1299 0.1522 0.1034 0.1314 0.1052 0.1526 0.0704 0.2976 0.0040 0.0039 0.0059 0.0071 0.0075 0.0092 0.0215 0.0184 0.0557 0.0417 0.0796 0.0708 0.0632 0.0565 0.0866 0.0877 0.6759 0.7047 0.0019 0.0022 0.0019 0.0013 0.0095 0.0056 0.0175 0.0233 0.0712 0.0739 0.1086 0.1188 0.0712 0.0774 0.1036 0.1059 0.6145 0.5916 0.0032 0.0064 0.0051 0.0185 0.0543 0.1006 0.0716 0.1016 0.6387
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1111 218 image if available 2639 15470 519.2 295.40 7.24 2.89 158 199 267 362 461 629 752 861 946 0.0584 904 1.018 61.29 17.26 1 0.0561 148 0.0024 14.54 6.516 0.3332 356819.0
281000000
236000000000
206000000000000
0.3341 0.2839 0.0000 0.0000 0.0026 0.0000 0.0102 0.0024 0.0332 0.0071 0.1969 0.0756 0.2123 0.1263 0.1637 0.0862 0.1867 0.1098 0.1944 0.5927 0.0000 0.0000 0.0007 0.0000 0.0014 0.0012 0.0014 0.0018 0.0254 0.0257 0.0357 0.0293 0.0254 0.0246 0.0460 0.0334 0.8640 0.8841 0.0000 0.0000 0.0000 0.0000 0.0000 0.0012 0.0019 0.0058 0.0319 0.0255 0.0432 0.0638 0.0244 0.0290 0.0413 0.0348 0.8573 0.8399 0.0000 0.0000 0.0000 0.0008 0.0262 0.0467 0.0213 0.0344 0.8705 3 5 6 6 7 8 9 10 11 0.1427 0.45 0.999 0.4303 60.8
577.971
6348.95
88018.5
0.4997 0.1587 0.0222 0.0021 0.0836 0.0094 0.1754 0.0371 0.2398 0.0855 0.2237 0.1719 0.1606 0.2362 0.0727 0.2550 0.0202 0.1567 0.0017 0.0461 0.0016 0.0002 0.0068 0.0010 0.0283 0.0046 0.0631 0.0161 0.1191 0.0465 0.1675 0.1004 0.2085 0.1888 0.2349 0.2956 0.1701 0.3468 0.0733 0.1314 0.1319 0.2046 0.1568 0.2008 0.1465 0.1602 0.1442 0.1368 0.1434 0.0882 0.1027 0.0454 0.0718 0.0227 0.0294 0.0099 0.0130 0.0314 0.0618 0.0977 0.1424 0.1625 0.1874 0.1808 0.1230
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 481 100 image if available 7950 9207 278.6 129.42 10.26 12.06 144 163 187 215 241 273 314 413 495 0.0924 851 0.695 94.53 15.03 6 0.0267 212 0.0018 9.35 6.724 0.3596 94338.5
37400000
16500000000
7810000000000
0.4212 0.2162 0.0009 0.0016 0.0013 0.0016 0.0068 0.0043 0.0175 0.0086 0.0554 0.0374 0.0967 0.0491 0.0797 0.0423 0.1121 0.0623 0.6297 0.7930 0.0004 0.0011 0.0007 0.0010 0.0027 0.0027 0.0064 0.0047 0.0202 0.0199 0.0282 0.0236 0.0285 0.0216 0.0407 0.0308 0.8721 0.8946 0.0009 0.0000 0.0009 0.0000 0.0028 0.0017 0.0070 0.0091 0.0167 0.0205 0.0423 0.0400 0.0265 0.0377 0.0307 0.0354 0.8721 0.8556 0.0010 0.0016 0.0049 0.0092 0.0191 0.0384 0.0309 0.0427 0.8521 3 5 5 6 7 8 9 11 19 0.1322 0.45 1.509 0.5124 250.6
12213
813301
62700000
0.5153 0.1526 0.0886 0.0079 0.2162 0.0407 0.2503 0.0797 0.2088 0.1421 0.1362 0.1824 0.0696 0.1959 0.0225 0.1743 0.0078 0.1275 0.0000 0.0493 0.0425 0.0045 0.1012 0.0274 0.1320 0.0540 0.1129 0.0995 0.0975 0.1431 0.0935 0.1554 0.0649 0.1304 0.0728 0.1196 0.2827 0.2662 0.0790 0.0376 0.0515 0.0295 0.0334 0.0302 0.0322 0.0376 0.0632 0.0604 0.0971 0.1150 0.0872 0.0825 0.0989 0.1098 0.4576 0.4974 0.1005 0.0895 0.0781 0.0561 0.0570 0.0875 0.0557 0.0858 0.3897
SK-BR-3 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 524 311 image if available 7833 16316 159.4 129.05 84.65 174.06 65 76 86 97 114 131 150 185 382 0.0834 1360 1.188 60.96 23.71 5 0.0200 157 0.0057 7.18 5.903 0.4831 42052.4
16100000
7440000000
3750000000000
0.4134 0.2024 0.0022 0.0044 0.0039 0.0032 0.0061 0.0041 0.0335 0.0116 0.0754 0.0367 0.0972 0.0576 0.0972 0.0547 0.1056 0.0789 0.5788 0.7488 0.0012 0.0031 0.0021 0.0023 0.0027 0.0029 0.0140 0.0079 0.0273 0.0211 0.0334 0.0280 0.0404 0.0320 0.0507 0.0445 0.8282 0.8580 0.0007 0.0000 0.0007 0.0000 0.0033 0.0000 0.0086 0.0022 0.0213 0.0230 0.0452 0.0445 0.0219 0.0208 0.0359 0.0408 0.8625 0.8687 0.0005 0.0039 0.0043 0.0096 0.0294 0.0487 0.0352 0.0545 0.8140 8 10 12 15 18 24 39 87 242 0.1992 8.64 2.988 0.7068 37461.6
26400000
22100000000
20600000000000
0.5330 0.1352 0.0090 0.0029 0.0336 0.0070 0.0493 0.0187 0.1087 0.0531 0.1659 0.0904 0.1839 0.1376 0.1390 0.1405 0.1312 0.1359 0.1794 0.4140 0.0005 0.0009 0.0029 0.0023 0.0029 0.0042 0.0098 0.0168 0.0383 0.0349 0.0554 0.0519 0.0449 0.0496 0.0660 0.0575 0.7794 0.7817 0.0021 0.0004 0.0017 0.0035 0.0045 0.0047 0.0141 0.0116 0.0497 0.0520 0.0783 0.0849 0.0583 0.0621 0.0852 0.0791 0.7060 0.7017 0.0009 0.0033 0.0045 0.0117 0.0415 0.0667 0.0505 0.0739 0.7471
MCF7 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1103 521 image if available 38572 41531 83.7 70.09 7.10 2.74 45 48 50 53 56 62 73 98 152 0.0457 1898 0.782 128.16 45.34 3 0.0101 390 0.0492 1.50 4.084 0.6882 11919.8
2870000
920000000
334000000000
0.4510 0.1895 0.0109 0.0089 0.0164 0.0172 0.0246 0.0246 0.0351 0.0389 0.0605 0.0504 0.0801 0.0590 0.0958 0.0673 0.1409 0.0885 0.5357 0.6452 0.0040 0.0067 0.0055 0.0130 0.0089 0.0188 0.0105 0.0286 0.0183 0.0354 0.0237 0.0412 0.0271 0.0468 0.0418 0.0594 0.8604 0.7500 0.0015 0.0009 0.0027 0.0019 0.0047 0.0041 0.0104 0.0090 0.0173 0.0159 0.0259 0.0282 0.0314 0.0309 0.0401 0.0398 0.8660 0.8695 0.0020 0.0024 0.0056 0.0088 0.0174 0.0214 0.0294 0.0366 0.8764 4 5 6 6 7 8 8 9 11 0.4747 0.33 1.180 0.8414 57.9
527.37
5295.83
58155.7
0.4995 0.1829 0.0184 0.0024 0.0723 0.0096 0.1551 0.0301 0.2242 0.0749 0.2394 0.1555 0.1742 0.2423 0.0889 0.2556 0.0251 0.1713 0.0024 0.0583 0.0022 0.0001 0.0106 0.0010 0.0291 0.0053 0.0623 0.0178 0.1060 0.0556 0.1606 0.1162 0.2066 0.1940 0.2316 0.2914 0.1910 0.3187 0.0905 0.1632 0.1612 0.2060 0.1796 0.1882 0.1754 0.1469 0.1412 0.1102 0.1007 0.0685 0.0624 0.0461 0.0489 0.0412 0.0401 0.0296 0.0110 0.0392 0.0830 0.1233 0.1517 0.1724 0.1677 0.1502 0.1015
MDA-MB-231 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 1132 783 image if available 5806 15602 539.4 203.19 87.63 159.39 237 320 418 529 593 630 664 708 771 0.0657 1025 0.615 160.90 32.02 5 0.0725 421 0.0005 70.80 7.812 0.1691 332268.0
221000000
155000000000
113000000000000
0.4107 0.2133 0.0000 0.0000 0.0015 0.0005 0.0067 0.0003 0.0370 0.0061 0.1090 0.0389 0.1697 0.0718 0.1398 0.0509 0.1506 0.0799 0.3856 0.7517 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0035 0.0013 0.0213 0.0203 0.0424 0.0428 0.0263 0.0197 0.0354 0.0324 0.8711 0.8834 0.0015 0.0000 0.0078 0.0000 0.0069 0.0000 0.0206 0.0000 0.0553 0.0000 0.0852 0.0000 0.0715 0.0000 0.0832 0.0000 0.6681 1.0000 0.0003 0.0000 0.0003 0.0038 0.0262 0.0487 0.0324 0.0461 0.8422 6 8 9 11 14 23 51 120 297 0.1136 5.25 3.423 0.5908 33081.1
18000000
11400000000
7790000000000
0.5377 0.1183 0.0619 0.0026 0.1417 0.0166 0.2366 0.0806 0.1761 0.1157 0.1747 0.1905 0.0894 0.2027 0.0688 0.1381 0.0303 0.1234 0.0206 0.1298 0.0010 0.0002 0.0007 0.0002 0.0020 0.0017 0.0110 0.0119 0.0483 0.0430 0.0841 0.0733 0.0507 0.0497 0.0741 0.0696 0.7281 0.7502 0.0003 0.0007 0.0012 0.0036 0.0056 0.0029 0.0148 0.0180 0.0545 0.0546 0.0898 0.0971 0.0634 0.0605 0.0756 0.0840 0.6947 0.6788 0.0003 0.0005 0.0038 0.0110 0.0513 0.0880 0.0548 0.0784 0.7120
MDA-MB-231 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 591 322 image if available 3805 8120 447.6 140.46 62.41 102.20 225 309 397 453 481 505 531 568 598 0.0792 643 1.179 95.75 35.78 2 0.0636 242 0.0012 24.22 7.023 0.2589 220069.0
114000000
61800000000
34400000000000
0.3868 0.2449 0.0017 0.0000 0.0000 0.0000 0.0011 0.0003 0.0114 0.0030 0.0542 0.0207 0.0787 0.0353 0.0685 0.0267 0.1038 0.0443 0.6805 0.8697 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0014 0.0019 0.0183 0.0158 0.0254 0.0260 0.0183 0.0167 0.0268 0.0236 0.9097 0.9160 0.0009 0.0000 0.0037 0.0000 0.0083 0.0000 0.0111 0.0000 0.0426 0.0000 0.0546 0.0000 0.0592 0.0000 0.0823 0.0000 0.7373 1.0000 0.0000 0.0000 0.0017 0.0047 0.0236 0.0356 0.0347 0.0592 0.8404 8 9 11 12 16 24 45 91 190 0.1789 5.12 3.242 0.6875 14337.8
5250000
2370000000
1220000000000
0.6067 0.0913 0.0581 0.0060 0.1183 0.0249 0.1618 0.0957 0.1390 0.1256 0.1784 0.1446 0.1515 0.1605 0.1224 0.1296 0.0456 0.0987 0.0249 0.2144 0.0017 0.0015 0.0035 0.0026 0.0035 0.0045 0.0138 0.0146 0.0558 0.0544 0.0878 0.0773 0.0636 0.0484 0.0930 0.0926 0.6775 0.7041 0.0005 0.0006 0.0005 0.0006 0.0033 0.0024 0.0169 0.0192 0.0754 0.0800 0.1038 0.1191 0.0644 0.0565 0.1032 0.1179 0.6319 0.6037 0.0010 0.0034 0.0039 0.0186 0.0658 0.0932 0.0677 0.0991 0.6472
MDA-MB-231 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 1028 231 image if available 11368 9358 393.3 133.58 93.30 136.68 187 274 336 383 422 451 481 509 544 0.1038 971 0.530 101.02 17.03 7 0.0223 254 0.0009 24.62 7.358 0.2464 172513.0
80400000
39000000000
19500000000000
0.5210 0.1387 0.0011 0.0006 0.0017 0.0005 0.0047 0.0018 0.0170 0.0049 0.0766 0.0277 0.1275 0.0545 0.1031 0.0384 0.1389 0.0594 0.5294 0.8122 0.0000 0.0001 0.0001 0.0001 0.0000 0.0002 0.0023 0.0012 0.0230 0.0184 0.0392 0.0346 0.0241 0.0188 0.0387 0.0285 0.8726 0.8980 0.0005 0.0000 0.0029 0.0000 0.0061 0.0000 0.0163 0.0000 0.0472 0.0000 0.0674 0.0000 0.0653 0.0000 0.0888 0.0000 0.7054 1.0000 0.0003 0.0002 0.0009 0.0047 0.0314 0.0487 0.0382 0.0542 0.8214 10 12 15 20 34 52 79 150 276 0.1156 10.49 4.045 0.6216 27384.8
12500000
7130000000
4620000000000
0.4672 0.1594 0.0875 0.0139 0.2611 0.0541 0.2439 0.2073 0.1148 0.1314 0.0933 0.1294 0.0689 0.1208 0.0473 0.0812 0.0445 0.0759 0.0387 0.1861 0.0003 0.0020 0.0031 0.0022 0.0037 0.0053 0.0252 0.0193 0.0857 0.0735 0.1244 0.1092 0.0857 0.0732 0.1163 0.1151 0.5556 0.6003 0.0000 0.0000 0.0004 0.0010 0.0045 0.0077 0.0254 0.0305 0.0994 0.1056 0.1582 0.1608 0.0856 0.0944 0.1270 0.1370 0.4996 0.4630 0.0008 0.0044 0.0044 0.0252 0.0913 0.1442 0.0873 0.1197 0.5226
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 771 431 image if available 4723 9875 420.9 161.67 55.15 99.89 200 251 303 365 431 482 522 568 629 0.0788 778 0.731 105.48 21.21 6 0.0565 267 0.0006 80.85 7.710 0.1749 203288.0
108000000
61500000000
36800000000000
0.4984 0.1471 0.0007 0.0003 0.0007 0.0010 0.0216 0.0033 0.0404 0.0080 0.1246 0.0501 0.1865 0.0951 0.1461 0.0607 0.1538 0.0921 0.3257 0.6894 0.0000 0.0000 0.0000 0.0000 0.0003 0.0000 0.0046 0.0034 0.0355 0.0308 0.0624 0.0490 0.0309 0.0300 0.0558 0.0477 0.8106 0.8391 0.0012 0.0000 0.0025 0.0000 0.0037 0.0000 0.0211 0.0000 0.0460 0.0000 0.0814 0.0000 0.0534 0.0000 0.0764 0.0000 0.7141 1.0000 0.0000 0.0000 0.0004 0.0061 0.0442 0.0626 0.0421 0.0646 0.7799 10 11 12 13 15 20 30 66 151 0.2033 1.45 2.515 0.7047 13017.7
5530000
3000000000
1870000000000
0.6272 0.0766 0.0281 0.0028 0.0884 0.0139 0.1165 0.0558 0.1908 0.0883 0.2028 0.1403 0.1767 0.1589 0.1145 0.1608 0.0643 0.1673 0.0181 0.2119 0.0004 0.0007 0.0008 0.0010 0.0012 0.0042 0.0132 0.0178 0.0474 0.0437 0.0783 0.0615 0.0602 0.0612 0.0799 0.0829 0.7186 0.7269 0.0000 0.0000 0.0010 0.0011 0.0055 0.0056 0.0146 0.0202 0.0592 0.0633 0.0933 0.0959 0.0607 0.0774 0.0933 0.0970 0.6724 0.6396 0.0005 0.0000 0.0027 0.0140 0.0564 0.0794 0.0609 0.0947 0.6916
MDA-MB-231 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 680 102 image if available 4304 6744 541.8 144.02 32.62 45.34 329 395 450 516 566 606 638 670 705 0.0948 639 0.542 117.00 26.02 1 0.0853 367 0.0008 32.43 7.325 0.2185 314288.0
192000000
122000000000
80400000000000
0.3875 0.2444 0.0010 0.0000 0.0025 0.0003 0.0069 0.0003 0.0212 0.0022 0.0562 0.0210 0.0877 0.0339 0.0946 0.0234 0.1252 0.0358 0.6047 0.8831 0.0000 0.0000 0.0000 0.0003 0.0006 0.0003 0.0044 0.0015 0.0197 0.0172 0.0292 0.0288 0.0251 0.0175 0.0368 0.0275 0.8842 0.9070 0.0000 0.0000 0.0080 0.0000 0.0187 0.0000 0.0276 0.0000 0.0480 0.0000 0.0730 0.0000 0.0747 0.0000 0.1103 0.0000 0.6397 1.0000 0.0000 0.0013 0.0017 0.0055 0.0233 0.0355 0.0364 0.0508 0.8455 8 9 11 12 15 18 26 44 83 0.2567 1.27 2.377 0.7837 3119.9
589671
172000000
67600000000
0.6419 0.0827 0.0252 0.0246 0.1124 0.0419 0.1550 0.0583 0.2190 0.0887 0.1725 0.1297 0.1570 0.1478 0.1066 0.1445 0.0504 0.1650 0.0019 0.1995 0.0035 0.0115 0.0080 0.0167 0.0141 0.0199 0.0251 0.0267 0.0693 0.0554 0.1065 0.0940 0.0749 0.0737 0.0965 0.0992 0.6020 0.6029 0.0034 0.0031 0.0054 0.0085 0.0075 0.0124 0.0360 0.0325 0.0658 0.0688 0.1126 0.1145 0.0855 0.0828 0.1119 0.1121 0.5719 0.5654 0.0012 0.0070 0.0153 0.0282 0.0728 0.1045 0.0752 0.1057 0.5901
MDA-MB-231 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 637 251 image if available 4831 6157 434.9 144.34 87.99 128.76 226 293 353 413 455 489 520 554 622 0.1176 724 0.741 143.63 44.91 2 0.0909 439 0.0009 28.38 7.266 0.2359 209951.0
109000000
59200000000
33500000000000
0.3927 0.2352 0.0015 0.0000 0.0035 0.0000 0.0050 0.0003 0.0179 0.0042 0.0601 0.0282 0.1118 0.0434 0.0860 0.0299 0.1143 0.0511 0.5999 0.8429 0.0000 0.0000 0.0003 0.0000 0.0003 0.0002 0.0023 0.0022 0.0216 0.0210 0.0347 0.0259 0.0213 0.0213 0.0361 0.0291 0.8835 0.9002 0.0007 0.0000 0.0035 0.0000 0.0084 0.0000 0.0169 0.0000 0.0443 0.0000 0.0718 0.0000 0.0577 0.0000 0.0809 0.0000 0.7157 1.0000 0.0000 0.0007 0.0011 0.0048 0.0257 0.0432 0.0313 0.0555 0.8375 9 11 13 18 26 42 87 147 262 0.1247 11.17 3.769 0.6386 24317.8
10200000
5220000000
3080000000000
0.5729 0.1008 0.0398 0.0089 0.1273 0.0316 0.1777 0.0671 0.1751 0.0886 0.1565 0.1696 0.1008 0.1810 0.0955 0.1405 0.0822 0.1329 0.0451 0.1797 0.0005 0.0004 0.0020 0.0027 0.0025 0.0027 0.0094 0.0093 0.0480 0.0409 0.0762 0.0721 0.0574 0.0503 0.0826 0.0730 0.7216 0.7486 0.0000 0.0007 0.0018 0.0000 0.0030 0.0048 0.0152 0.0213 0.0626 0.0810 0.1027 0.1071 0.0699 0.1009 0.1240 0.1263 0.6207 0.5580 0.0000 0.0005 0.0016 0.0114 0.0565 0.0864 0.0549 0.1010 0.6877