High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
MCF7 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1201 147 image if available 25401 21792 80.3 36.47 7.79 3.16 47 51 55 60 67 79 95 111 130 0.0646 1407 0.643 109.48 22.02 3 0.0122 311 0.0238 1.54 4.339 0.6433 7784.7
930349
141000000
27400000000
0.3746 0.2574 0.0183 0.0041 0.0285 0.0101 0.0332 0.0165 0.0445 0.0216 0.0579 0.0307 0.0760 0.0454 0.0991 0.0645 0.1547 0.1011 0.4878 0.7059 0.0063 0.0025 0.0088 0.0051 0.0101 0.0093 0.0128 0.0127 0.0158 0.0171 0.0202 0.0254 0.0263 0.0353 0.0450 0.0545 0.8547 0.8381 0.0029 0.0096 0.0051 0.0076 0.0087 0.0135 0.0154 0.0237 0.0181 0.0317 0.0252 0.0416 0.0356 0.0590 0.0614 0.0833 0.8277 0.7300 0.0039 0.0045 0.0066 0.0106 0.0121 0.0194 0.0250 0.0402 0.8777 4 5 6 7 8 9 9 10 12 0.3288 0.54 1.489 0.7679 70.7
710.738
7758.34
90867.1
0.5651 0.1468 0.0276 0.0002 0.1012 0.0027 0.1830 0.0162 0.2395 0.0448 0.2232 0.1065 0.1440 0.1983 0.0622 0.2724 0.0175 0.2494 0.0018 0.1095 0.0011 0.0001 0.0095 0.0007 0.0313 0.0047 0.0743 0.0148 0.1392 0.0405 0.2209 0.1002 0.2544 0.1989 0.1985 0.3291 0.0707 0.3109 0.0837 0.3817 0.2220 0.3524 0.2715 0.1695 0.2102 0.0699 0.1317 0.0232 0.0547 0.0028 0.0218 0.0004 0.0035 0.0000 0.0010 0.0000 0.0061 0.0422 0.1149 0.1974 0.2403 0.2128 0.1308 0.0484 0.0072
SK-BR-3 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 953 241 image if available 4452 16651 514.3 202.79 16.75 22.48 264 314 365 425 496 574 650 721 776 0.0610 1016 0.831 150.81 30.46 9 0.0806 359 0.0007 46.67 7.524 0.1977 305620.0
203000000
146000000000
112000000000000
0.3891 0.2375 0.0008 0.0022 0.0000 0.0000 0.0142 0.0022 0.0334 0.0103 0.0943 0.0357 0.1060 0.0600 0.1018 0.0527 0.1277 0.0681 0.5217 0.7688 0.0000 0.0003 0.0000 0.0000 0.0015 0.0003 0.0036 0.0052 0.0259 0.0196 0.0353 0.0304 0.0230 0.0232 0.0383 0.0312 0.8724 0.8898 0.0000 0.0000 0.0000 0.0044 0.0019 0.0044 0.0045 0.0166 0.0408 0.0376 0.0388 0.0564 0.0323 0.0431 0.0511 0.0818 0.8305 0.7558 0.0000 0.0000 0.0000 0.0067 0.0262 0.0419 0.0295 0.0409 0.8548 6 7 8 9 11 14 17 22 30 0.1712 0.40 1.575 0.6158 785.9
143855
50100000
21000000000
0.6171 0.0868 0.0605 0.0488 0.0678 0.0590 0.0946 0.0585 0.1398 0.0738 0.1565 0.0814 0.1773 0.0904 0.1603 0.1323 0.1067 0.1903 0.0365 0.2655 0.0178 0.0287 0.0157 0.0319 0.0185 0.0277 0.0267 0.0319 0.0491 0.0406 0.0697 0.0463 0.0717 0.0582 0.1168 0.0921 0.6140 0.6425 0.0160 0.0168 0.0214 0.0291 0.0295 0.0412 0.0447 0.0496 0.0736 0.0814 0.0894 0.0941 0.1054 0.1129 0.1416 0.1313 0.4783 0.4436 0.0152 0.0164 0.0269 0.0290 0.0574 0.0696 0.0884 0.1384 0.5589
MDA-MB-231 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 469 438 image if available 2983 6904 291.5 155.73 25.80 36.51 163 179 192 210 232 259 292 423 579 0.1047 723 0.563 78.24 21.26 5 0.0865 258 0.0031 12.41 6.310 0.3653 109220.0
50500000
26800000000
15300000000000
0.4115 0.2245 0.0013 0.0000 0.0013 0.0011 0.0053 0.0049 0.0279 0.0152 0.0810 0.0455 0.1514 0.0829 0.1142 0.0650 0.1116 0.0861 0.5060 0.6994 0.0007 0.0000 0.0007 0.0008 0.0027 0.0036 0.0129 0.0101 0.0278 0.0283 0.0394 0.0449 0.0455 0.0377 0.0502 0.0494 0.8201 0.8251 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0042 0.0048 0.0250 0.0353 0.0722 0.0609 0.0222 0.0304 0.0431 0.0529 0.8333 0.8157 0.0000 0.0022 0.0078 0.0100 0.0288 0.0654 0.0310 0.0488 0.8060 7 9 10 12 14 17 22 30 49 0.1051 1.66 3.110 0.7374 1998.1
320182
69200000
17600000000
0.5249 0.1326 0.0229 0.0158 0.0439 0.0273 0.0768 0.0379 0.1286 0.0532 0.1655 0.0873 0.1864 0.1237 0.1685 0.1324 0.1256 0.1938 0.0818 0.3285 0.0053 0.0100 0.0107 0.0158 0.0191 0.0197 0.0364 0.0262 0.0631 0.0494 0.1039 0.0862 0.0795 0.0733 0.0955 0.1172 0.5866 0.6021 0.0056 0.0129 0.0104 0.0069 0.0288 0.0247 0.0400 0.0366 0.0737 0.0791 0.1017 0.1098 0.0745 0.0692 0.1129 0.0930 0.5524 0.5678 0.0070 0.0152 0.0275 0.0427 0.0719 0.1029 0.0830 0.0918 0.5582
SK-BR-3 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 1220 451 image if available 11232 18145 198.9 80.62 6.13 2.92 96 118 138 163 190 224 254 281 308 0.0881 1598 0.402 135.09 20.03 6 0.0363 408 0.0017 7.54 6.630 0.3605 46068.3
11900000
3280000000
953000000000
0.4257 0.1921 0.0034 0.0015 0.0058 0.0030 0.0089 0.0074 0.0294 0.0164 0.0684 0.0406 0.1042 0.0619 0.1097 0.0584 0.1415 0.0780 0.5287 0.7328 0.0006 0.0003 0.0010 0.0001 0.0022 0.0029 0.0064 0.0067 0.0146 0.0168 0.0254 0.0283 0.0235 0.0230 0.0296 0.0320 0.8967 0.8898 0.0005 0.0025 0.0033 0.0051 0.0060 0.0132 0.0098 0.0229 0.0280 0.0467 0.0282 0.0642 0.0358 0.0778 0.0499 0.0999 0.8385 0.6677 0.0009 0.0007 0.0024 0.0073 0.0189 0.0239 0.0284 0.0375 0.8799 3 4 5 5 6 7 7 8 9 0.1305 0.44 1.002 0.4054 46.1
458.785
7687.85
234458
0.5483 0.1268 0.0123 0.0015 0.0555 0.0107 0.1399 0.0297 0.2151 0.0734 0.2476 0.1533 0.1919 0.2308 0.1031 0.2579 0.0306 0.1797 0.0042 0.0631 0.0008 0.0001 0.0083 0.0014 0.0270 0.0074 0.0633 0.0263 0.1189 0.0658 0.1643 0.1156 0.2017 0.2003 0.2201 0.2840 0.1956 0.2992 0.1197 0.2233 0.1816 0.2100 0.1733 0.1903 0.1579 0.1256 0.1231 0.0803 0.0916 0.0538 0.0625 0.0439 0.0525 0.0381 0.0379 0.0347 0.0066 0.0454 0.0962 0.1383 0.1787 0.1873 0.1512 0.1164 0.0797
SK-BR-3
0
DRAQ5 1 TMRE 2 2 2 1 927 522 image if available 3614 6289 297.5 144.28 59.44 77.60 127 157 192 233 266 305 406 465 511 0.1040 654 1.229 109.25 47.52 2 0.0819 296 0.0028 6.07 6.131 0.4083 109347.0
45800000
20700000000
9820000000000
0.3640 0.2549 0.0012 0.0000 0.0012 0.0006 0.0036 0.0025 0.0324 0.0086 0.1032 0.0531 0.1429 0.0834 0.1273 0.0562 0.1020 0.0828 0.4862 0.7128 0.0005 0.0000 0.0005 0.0004 0.0005 0.0015 0.0076 0.0030 0.0219 0.0203 0.0343 0.0263 0.0281 0.0192 0.0357 0.0312 0.8710 0.8980 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0016 0.0039 0.0331 0.0347 0.0410 0.0597 0.0316 0.0414 0.0458 0.0462 0.8469 0.8141 0.0020 0.0013 0.0027 0.0054 0.0229 0.0404 0.0242 0.0310 0.8700 8 11 14 19 26 38 58 92 162 0.0962 2.42 3.459 0.6933 9553.8
2410000
755000000
271000000000
0.5400 0.1318 0.0018 0.0033 0.0126 0.0122 0.0650 0.0236 0.1733 0.0447 0.2365 0.0943 0.2166 0.1561 0.1480 0.1423 0.1137 0.1740 0.0325 0.3496 0.0000 0.0015 0.0005 0.0034 0.0032 0.0076 0.0142 0.0125 0.0500 0.0386 0.0866 0.0773 0.0596 0.0583 0.0830 0.0735 0.7030 0.7273 0.0000 0.0000 0.0012 0.0014 0.0037 0.0064 0.0197 0.0227 0.0614 0.0716 0.1020 0.1106 0.0694 0.0738 0.0860 0.0865 0.6566 0.6270 0.0011 0.0027 0.0043 0.0160 0.0543 0.1005 0.0660 0.0787 0.6766
SK-BR-3
0
DRAQ5 1 TMRE 2 2 2 1 811 224 image if available 3862 6781 328.4 152.30 138.02 238.95 140 175 209 260 309 370 436 481 535 0.0967 656 1.166 181.47 58.73 2 0.1144 442 0.0022 6.00 6.354 0.3863 131046.0
59300000
29000000000
15000000000000
0.3371 0.2738 0.0023 0.0005 0.0000 0.0011 0.0046 0.0043 0.0230 0.0097 0.0908 0.0500 0.1517 0.0844 0.1287 0.0580 0.1356 0.0876 0.4632 0.7045 0.0004 0.0000 0.0000 0.0000 0.0004 0.0004 0.0048 0.0007 0.0205 0.0209 0.0301 0.0301 0.0261 0.0195 0.0305 0.0280 0.8872 0.9005 0.0000 0.0000 0.0000 0.0010 0.0007 0.0052 0.0091 0.0207 0.0252 0.0342 0.0379 0.0726 0.0344 0.0654 0.0456 0.0840 0.8471 0.7168 0.0000 0.0000 0.0022 0.0039 0.0257 0.0363 0.0262 0.0312 0.8745 11 14 19 24 34 55 99 200 413 0.0754 21.49 4.311 0.6192 76139.6
68600000
77600000000
100000000000000
0.5118 0.1375 0.0101 0.0061 0.0553 0.0073 0.1508 0.0340 0.1508 0.0643 0.2462 0.1541 0.1683 0.2184 0.0955 0.1311 0.0628 0.1226 0.0603 0.2621 0.0000 0.0014 0.0021 0.0023 0.0057 0.0027 0.0114 0.0099 0.0532 0.0537 0.0749 0.0722 0.0583 0.0550 0.0800 0.0753 0.7145 0.7276 0.0000 0.0000 0.0039 0.0022 0.0039 0.0036 0.0123 0.0129 0.0578 0.0646 0.0884 0.0940 0.0676 0.0560 0.0799 0.0933 0.6862 0.6734 0.0006 0.0029 0.0053 0.0117 0.0516 0.0844 0.0668 0.0850 0.6917
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 566 807 image if available 4751 7725 404.9 192.17 127.70 196.98 142 186 268 341 396 464 540 611 670 0.1111 858 1.078 54.04 18.87 1 0.0280 133 0.0027 8.16 6.352 0.3795 200834.0
112000000
66500000000
41200000000000
0.3420 0.2744 0.0000 0.0005 0.0008 0.0005 0.0016 0.0005 0.0219 0.0064 0.0926 0.0401 0.1300 0.0724 0.1024 0.0519 0.1446 0.0738 0.5061 0.7540 0.0000 0.0000 0.0000 0.0000 0.0003 0.0000 0.0033 0.0003 0.0189 0.0153 0.0314 0.0269 0.0245 0.0136 0.0453 0.0266 0.8762 0.9173 0.0000 0.0000 0.0000 0.0008 0.0011 0.0008 0.0050 0.0111 0.0296 0.0325 0.0369 0.0507 0.0335 0.0428 0.0464 0.0642 0.8475 0.7971 0.0000 0.0004 0.0000 0.0104 0.0265 0.0370 0.0313 0.0487 0.8456 7 9 11 16 28 63 121 222 412 0.0706 13.58 4.145 0.5200 55103.2
34600000
26500000000
23100000000000
0.6752 0.0630 0.0314 0.0009 0.1458 0.0204 0.2288 0.0814 0.1513 0.1230 0.1439 0.1748 0.1328 0.1832 0.0627 0.1221 0.0424 0.1240 0.0609 0.1702 0.0008 0.0000 0.0008 0.0003 0.0020 0.0007 0.0106 0.0115 0.0701 0.0687 0.1133 0.0965 0.0830 0.0767 0.1251 0.1154 0.5943 0.6302 0.0015 0.0000 0.0035 0.0028 0.0095 0.0084 0.0160 0.0302 0.0845 0.0878 0.1191 0.1270 0.1046 0.1079 0.1251 0.1208 0.5363 0.5151 0.0000 0.0013 0.0013 0.0191 0.0756 0.1250 0.0894 0.1299 0.5583
SK-BR-3
0
DRAQ5 1 TMRE 2 2 2 1 758 118 image if available 3722 7678 368.8 182.51 164.24 272.94 145 178 217 266 351 446 510 563 614 0.0847 650 1.108 87.24 31.58 2 0.0623 232 0.0018 10.54 6.623 0.3115 169332.0
88000000
48900000000
28300000000000
0.2899 0.3386 0.0000 0.0007 0.0000 0.0027 0.0086 0.0047 0.0310 0.0167 0.1480 0.0670 0.2220 0.0965 0.1463 0.0810 0.1911 0.1186 0.2530 0.6122 0.0000 0.0000 0.0000 0.0008 0.0010 0.0020 0.0029 0.0035 0.0201 0.0203 0.0315 0.0250 0.0220 0.0238 0.0382 0.0355 0.8844 0.8892 0.0000 0.0009 0.0000 0.0009 0.0000 0.0019 0.0066 0.0149 0.0238 0.0411 0.0416 0.0747 0.0350 0.0691 0.0430 0.0756 0.8500 0.7208 0.0000 0.0000 0.0006 0.0017 0.0251 0.0345 0.0239 0.0395 0.8747 12 17 22 28 43 72 114 240 499 0.0621 27.12 4.594 0.6002 101458.0
93500000
101000000000
118000000000000
0.3873 0.2579 0.0278 0.0021 0.0732 0.0103 0.1995 0.0372 0.1692 0.0702 0.1843 0.1569 0.1162 0.1610 0.0909 0.1352 0.0707 0.1197 0.0682 0.3075 0.0019 0.0000 0.0014 0.0028 0.0053 0.0035 0.0101 0.0102 0.0483 0.0501 0.0718 0.0654 0.0565 0.0556 0.0775 0.0832 0.7271 0.7292 0.0000 0.0006 0.0041 0.0006 0.0053 0.0026 0.0077 0.0057 0.0543 0.0529 0.0721 0.0861 0.0543 0.0529 0.0874 0.0848 0.7147 0.7136 0.0005 0.0027 0.0086 0.0065 0.0507 0.0706 0.0507 0.0841 0.7256
SK-BR-3 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 1199 461 image if available 4972 6147 193.3 101.39 92.03 198.27 86 103 120 137 155 189 252 298 348 0.1223 752 0.646 151.35 28.23 6 0.0686 341 0.0019 14.93 6.742 0.3352 47639.3
13900000
4520000000
1570000000000
0.3496 0.2649 0.0060 0.0004 0.0048 0.0035 0.0132 0.0052 0.0396 0.0148 0.1321 0.0461 0.2233 0.0804 0.1417 0.0722 0.1573 0.1039 0.2821 0.6735 0.0016 0.0003 0.0016 0.0017 0.0036 0.0011 0.0084 0.0058 0.0244 0.0172 0.0407 0.0302 0.0339 0.0266 0.0395 0.0388 0.8462 0.8784 0.0000 0.0008 0.0006 0.0015 0.0012 0.0061 0.0096 0.0107 0.0215 0.0313 0.0413 0.0595 0.0311 0.0489 0.0431 0.0794 0.8516 0.7618 0.0005 0.0000 0.0005 0.0046 0.0245 0.0408 0.0245 0.0362 0.8684 6 7 9 10 13 18 35 93 274 0.1539 10.11 3.626 0.6621 47772.6
36200000
31300000000
29200000000000
0.4667 0.1877 0.0120 0.0059 0.0518 0.0098 0.1076 0.0234 0.1992 0.0508 0.2231 0.1484 0.1673 0.2266 0.0916 0.1348 0.0598 0.1465 0.0876 0.2539 0.0007 0.0013 0.0036 0.0026 0.0051 0.0078 0.0182 0.0156 0.0547 0.0591 0.0591 0.0604 0.0562 0.0558 0.0795 0.0734 0.7228 0.7240 0.0000 0.0010 0.0063 0.0019 0.0063 0.0039 0.0116 0.0068 0.0634 0.0623 0.0598 0.0700 0.0625 0.0623 0.0938 0.0944 0.6964 0.6975 0.0008 0.0041 0.0081 0.0122 0.0575 0.0632 0.0624 0.0875 0.7042
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1111 218 image if available 2639 15470 519.2 295.40 7.24 2.89 158 199 267 362 461 629 752 861 946 0.0584 904 1.018 61.29 17.26 1 0.0561 148 0.0024 14.54 6.516 0.3332 356819.0
281000000
236000000000
206000000000000
0.3341 0.2839 0.0000 0.0000 0.0026 0.0000 0.0102 0.0024 0.0332 0.0071 0.1969 0.0756 0.2123 0.1263 0.1637 0.0862 0.1867 0.1098 0.1944 0.5927 0.0000 0.0000 0.0007 0.0000 0.0014 0.0012 0.0014 0.0018 0.0254 0.0257 0.0357 0.0293 0.0254 0.0246 0.0460 0.0334 0.8640 0.8841 0.0000 0.0000 0.0000 0.0000 0.0000 0.0012 0.0019 0.0058 0.0319 0.0255 0.0432 0.0638 0.0244 0.0290 0.0413 0.0348 0.8573 0.8399 0.0000 0.0000 0.0000 0.0008 0.0262 0.0467 0.0213 0.0344 0.8705 3 5 6 6 7 8 9 10 11 0.1427 0.45 0.999 0.4303 60.8
577.971
6348.95
88018.5
0.4997 0.1587 0.0222 0.0021 0.0836 0.0094 0.1754 0.0371 0.2398 0.0855 0.2237 0.1719 0.1606 0.2362 0.0727 0.2550 0.0202 0.1567 0.0017 0.0461 0.0016 0.0002 0.0068 0.0010 0.0283 0.0046 0.0631 0.0161 0.1191 0.0465 0.1675 0.1004 0.2085 0.1888 0.2349 0.2956 0.1701 0.3468 0.0733 0.1314 0.1319 0.2046 0.1568 0.2008 0.1465 0.1602 0.1442 0.1368 0.1434 0.0882 0.1027 0.0454 0.0718 0.0227 0.0294 0.0099 0.0130 0.0314 0.0618 0.0977 0.1424 0.1625 0.1874 0.1808 0.1230
SK-BR-3 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 770 194 image if available 4106 14842 217.4 110.14 102.63 168.85 87 104 124 149 193 255 309 338 368 0.0595 883 0.734 130.10 25.02 4 0.0774 318 0.0016 20.13 6.862 0.2708 59394.7
18600000
6250000000
2190000000000
0.3003 0.3143 0.0017 0.0020 0.0017 0.0047 0.0050 0.0027 0.0199 0.0182 0.1393 0.0532 0.2703 0.1097 0.1294 0.0787 0.1592 0.1016 0.2736 0.6292 0.0000 0.0004 0.0000 0.0011 0.0005 0.0007 0.0014 0.0043 0.0199 0.0180 0.0398 0.0371 0.0172 0.0213 0.0330 0.0317 0.8883 0.8853 0.0000 0.0000 0.0000 0.0023 0.0019 0.0023 0.0025 0.0070 0.0243 0.0319 0.0473 0.0474 0.0230 0.0365 0.0398 0.0629 0.8613 0.8096 0.0000 0.0000 0.0010 0.0047 0.0210 0.0367 0.0257 0.0352 0.8756 12 15 18 23 35 53 82 137 279 0.0621 16.73 4.450 0.6158 39039.8
25800000
21500000000
20400000000000
0.5806 0.1178 0.0142 0.0012 0.0745 0.0050 0.1347 0.0255 0.1665 0.0751 0.1808 0.1211 0.1548 0.1645 0.1163 0.1413 0.0879 0.1463 0.0703 0.3200 0.0004 0.0002 0.0022 0.0006 0.0034 0.0017 0.0117 0.0140 0.0549 0.0436 0.0904 0.0624 0.0616 0.0618 0.0940 0.0822 0.6814 0.7336 0.0000 0.0000 0.0015 0.0028 0.0065 0.0070 0.0175 0.0228 0.0713 0.0831 0.1208 0.1189 0.0799 0.0856 0.1097 0.1140 0.5927 0.5658 0.0008 0.0024 0.0040 0.0129 0.0630 0.1018 0.0691 0.1036 0.6424
SK-BR-3 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 524 311 image if available 7833 16316 159.4 129.05 84.65 174.06 65 76 86 97 114 131 150 185 382 0.0834 1360 1.188 60.96 23.71 5 0.0200 157 0.0057 7.18 5.903 0.4831 42052.4
16100000
7440000000
3750000000000
0.4134 0.2024 0.0022 0.0044 0.0039 0.0032 0.0061 0.0041 0.0335 0.0116 0.0754 0.0367 0.0972 0.0576 0.0972 0.0547 0.1056 0.0789 0.5788 0.7488 0.0012 0.0031 0.0021 0.0023 0.0027 0.0029 0.0140 0.0079 0.0273 0.0211 0.0334 0.0280 0.0404 0.0320 0.0507 0.0445 0.8282 0.8580 0.0007 0.0000 0.0007 0.0000 0.0033 0.0000 0.0086 0.0022 0.0213 0.0230 0.0452 0.0445 0.0219 0.0208 0.0359 0.0408 0.8625 0.8687 0.0005 0.0039 0.0043 0.0096 0.0294 0.0487 0.0352 0.0545 0.8140 8 10 12 15 18 24 39 87 242 0.1992 8.64 2.988 0.7068 37461.6
26400000
22100000000
20600000000000
0.5330 0.1352 0.0090 0.0029 0.0336 0.0070 0.0493 0.0187 0.1087 0.0531 0.1659 0.0904 0.1839 0.1376 0.1390 0.1405 0.1312 0.1359 0.1794 0.4140 0.0005 0.0009 0.0029 0.0023 0.0029 0.0042 0.0098 0.0168 0.0383 0.0349 0.0554 0.0519 0.0449 0.0496 0.0660 0.0575 0.7794 0.7817 0.0021 0.0004 0.0017 0.0035 0.0045 0.0047 0.0141 0.0116 0.0497 0.0520 0.0783 0.0849 0.0583 0.0621 0.0852 0.0791 0.7060 0.7017 0.0009 0.0033 0.0045 0.0117 0.0415 0.0667 0.0505 0.0739 0.7471
MCF7 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1103 521 image if available 38572 41531 83.7 70.09 7.10 2.74 45 48 50 53 56 62 73 98 152 0.0457 1898 0.782 128.16 45.34 3 0.0101 390 0.0492 1.50 4.084 0.6882 11919.8
2870000
920000000
334000000000
0.4510 0.1895 0.0109 0.0089 0.0164 0.0172 0.0246 0.0246 0.0351 0.0389 0.0605 0.0504 0.0801 0.0590 0.0958 0.0673 0.1409 0.0885 0.5357 0.6452 0.0040 0.0067 0.0055 0.0130 0.0089 0.0188 0.0105 0.0286 0.0183 0.0354 0.0237 0.0412 0.0271 0.0468 0.0418 0.0594 0.8604 0.7500 0.0015 0.0009 0.0027 0.0019 0.0047 0.0041 0.0104 0.0090 0.0173 0.0159 0.0259 0.0282 0.0314 0.0309 0.0401 0.0398 0.8660 0.8695 0.0020 0.0024 0.0056 0.0088 0.0174 0.0214 0.0294 0.0366 0.8764 4 5 6 6 7 8 8 9 11 0.4747 0.33 1.180 0.8414 57.9
527.37
5295.83
58155.7
0.4995 0.1829 0.0184 0.0024 0.0723 0.0096 0.1551 0.0301 0.2242 0.0749 0.2394 0.1555 0.1742 0.2423 0.0889 0.2556 0.0251 0.1713 0.0024 0.0583 0.0022 0.0001 0.0106 0.0010 0.0291 0.0053 0.0623 0.0178 0.1060 0.0556 0.1606 0.1162 0.2066 0.1940 0.2316 0.2914 0.1910 0.3187 0.0905 0.1632 0.1612 0.2060 0.1796 0.1882 0.1754 0.1469 0.1412 0.1102 0.1007 0.0685 0.0624 0.0461 0.0489 0.0412 0.0401 0.0296 0.0110 0.0392 0.0830 0.1233 0.1517 0.1724 0.1677 0.1502 0.1015
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 481 100 image if available 7950 9207 278.6 129.42 10.26 12.06 144 163 187 215 241 273 314 413 495 0.0924 851 0.695 94.53 15.03 6 0.0267 212 0.0018 9.35 6.724 0.3596 94338.5
37400000
16500000000
7810000000000
0.4212 0.2162 0.0009 0.0016 0.0013 0.0016 0.0068 0.0043 0.0175 0.0086 0.0554 0.0374 0.0967 0.0491 0.0797 0.0423 0.1121 0.0623 0.6297 0.7930 0.0004 0.0011 0.0007 0.0010 0.0027 0.0027 0.0064 0.0047 0.0202 0.0199 0.0282 0.0236 0.0285 0.0216 0.0407 0.0308 0.8721 0.8946 0.0009 0.0000 0.0009 0.0000 0.0028 0.0017 0.0070 0.0091 0.0167 0.0205 0.0423 0.0400 0.0265 0.0377 0.0307 0.0354 0.8721 0.8556 0.0010 0.0016 0.0049 0.0092 0.0191 0.0384 0.0309 0.0427 0.8521 3 5 5 6 7 8 9 11 19 0.1322 0.45 1.509 0.5124 250.6
12213
813301
62700000
0.5153 0.1526 0.0886 0.0079 0.2162 0.0407 0.2503 0.0797 0.2088 0.1421 0.1362 0.1824 0.0696 0.1959 0.0225 0.1743 0.0078 0.1275 0.0000 0.0493 0.0425 0.0045 0.1012 0.0274 0.1320 0.0540 0.1129 0.0995 0.0975 0.1431 0.0935 0.1554 0.0649 0.1304 0.0728 0.1196 0.2827 0.2662 0.0790 0.0376 0.0515 0.0295 0.0334 0.0302 0.0322 0.0376 0.0632 0.0604 0.0971 0.1150 0.0872 0.0825 0.0989 0.1098 0.4576 0.4974 0.1005 0.0895 0.0781 0.0561 0.0570 0.0875 0.0557 0.0858 0.3897