High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1056 | 445 | | 5104 | 5780 | 74.9 | 19.31 | 218.45 | 175.33 | 50 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 100 | 0.1151 | 665 | 0.283 | 207.13 | 44.00 | 2 | 0.1532 | 782 | 0.0025 | 15.54 | 6.261 | 0.2795 | 5985.4 | 506947 | 45300000 | 4250000000 | 0.4661 | 0.1911 | 0.0004 | 0.0002 | 0.0039 | 0.0011 | 0.0191 | 0.0004 | 0.0399 | 0.0051 | 0.1042 | 0.0308 | 0.1402 | 0.0523 | 0.1568 | 0.0660 | 0.1812 | 0.0959 | 0.3543 | 0.7482 | 0.0000 | 0.0002 | 0.0010 | 0.0006 | 0.0066 | 0.0004 | 0.0081 | 0.0019 | 0.0403 | 0.0196 | 0.0608 | 0.0315 | 0.0613 | 0.0313 | 0.0861 | 0.0500 | 0.7359 | 0.8646 | 0.0063 | 0.0116 | 0.0188 | 0.0203 | 0.0385 | 0.0698 | 0.0626 | 0.1221 | 0.1181 | 0.1977 | 0.1503 | 0.1599 | 0.1351 | 0.1279 | 0.1485 | 0.1541 | 0.3220 | 0.1366 | 0.0024 | 0.0020 | 0.0083 | 0.0317 | 0.0797 | 0.1094 | 0.1023 | 0.1380 | 0.5262 | 37 | 65 | 100 | 137 | 174 | 217 | 278 | 349 | 460 | 0.0040 | 34.98 | 6.397 | 0.3275 | 78453.6 | 37400000 | 21600000000 | 14300000000000 | 0.5030 | 0.1632 | 0.0118 | 0.0034 | 0.0686 | 0.0049 | 0.1902 | 0.0303 | 0.1873 | 0.0654 | 0.2000 | 0.1563 | 0.1490 | 0.1904 | 0.0961 | 0.1553 | 0.0696 | 0.1484 | 0.0275 | 0.2456 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0045 | 0.0020 | 0.0170 | 0.0107 | 0.0701 | 0.0457 | 0.1114 | 0.0835 | 0.0947 | 0.0760 | 0.1218 | 0.0998 | 0.5791 | 0.6816 | 0.0000 | 0.0000 | 0.0048 | 0.0039 | 0.0064 | 0.0086 | 0.0301 | 0.0368 | 0.0924 | 0.1092 | 0.1557 | 0.1908 | 0.1090 | 0.1132 | 0.1557 | 0.1586 | 0.4458 | 0.3789 | 0.0009 | 0.0009 | 0.0035 | 0.0242 | 0.0797 | 0.1277 | 0.1035 | 0.1364 | 0.5234 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 751 | 267 | | 3996 | 13985 | 152.2 | 33.85 | 141.01 | 145.07 | 113 | 124 | 133 | 140 | 148 | 155 | 165 | 178 | 196 | 0.0633 | 885 | 1.001 | 83.55 | 24.08 | 2 | 0.0488 | 195 | 0.0021 | 21.13 | 6.445 | 0.2487 | 24325.1 | 4090000 | 723000000 | 135000000000 | 0.4071 | 0.2421 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0046 | 0.0000 | 0.0217 | 0.0008 | 0.0685 | 0.0210 | 0.1371 | 0.0445 | 0.1470 | 0.0450 | 0.1702 | 0.0623 | 0.4497 | 0.8264 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0072 | 0.0003 | 0.0302 | 0.0141 | 0.0688 | 0.0303 | 0.0676 | 0.0197 | 0.0894 | 0.0351 | 0.7352 | 0.9005 | 0.0015 | 0.0049 | 0.0160 | 0.0099 | 0.0248 | 0.0049 | 0.0758 | 0.1626 | 0.1487 | 0.1576 | 0.1662 | 0.1921 | 0.1122 | 0.1379 | 0.1327 | 0.1281 | 0.3222 | 0.2020 | 0.0033 | 0.0044 | 0.0116 | 0.0311 | 0.0843 | 0.1337 | 0.0943 | 0.1281 | 0.5092 | 19 | 33 | 50 | 68 | 90 | 118 | 157 | 223 | 339 | 0.0069 | 33.28 | 6.213 | 0.3970 | 40926.9 | 17700000 | 9520000000 | 5890000000000 | 0.6594 | 0.0769 | 0.0120 | 0.0022 | 0.0718 | 0.0095 | 0.1486 | 0.0217 | 0.1626 | 0.0638 | 0.1950 | 0.1371 | 0.1406 | 0.1875 | 0.1077 | 0.1501 | 0.0803 | 0.1521 | 0.0813 | 0.2760 | 0.0019 | 0.0005 | 0.0029 | 0.0029 | 0.0075 | 0.0052 | 0.0196 | 0.0142 | 0.0618 | 0.0479 | 0.0945 | 0.0817 | 0.0723 | 0.0641 | 0.1133 | 0.0906 | 0.6263 | 0.6929 | 0.0008 | 0.0003 | 0.0044 | 0.0049 | 0.0072 | 0.0097 | 0.0294 | 0.0346 | 0.0744 | 0.0822 | 0.1224 | 0.1275 | 0.0945 | 0.1005 | 0.1237 | 0.1287 | 0.5430 | 0.5117 | 0.0017 | 0.0042 | 0.0089 | 0.0256 | 0.0701 | 0.1033 | 0.0830 | 0.1114 | 0.5917 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 338 | 385 | | 6192 | 19742 | 233.9 | 53.78 | 137.63 | 180.46 | 171 | 188 | 203 | 216 | 228 | 242 | 256 | 273 | 303 | 0.0555 | 1095 | 1.184 | 93.43 | 33.02 | 1 | 0.0363 | 225 | 0.0009 | 46.43 | 7.247 | 0.1652 | 57591.1 | 14900000 | 4100000000 | 1190000000000 | 0.3895 | 0.2646 | 0.0000 | 0.0000 | 0.0018 | 0.0002 | 0.0041 | 0.0002 | 0.0216 | 0.0019 | 0.0685 | 0.0188 | 0.1277 | 0.0445 | 0.1508 | 0.0419 | 0.1815 | 0.0664 | 0.4442 | 0.8263 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0002 | 0.0094 | 0.0011 | 0.0292 | 0.0133 | 0.0619 | 0.0277 | 0.0581 | 0.0198 | 0.0873 | 0.0284 | 0.7507 | 0.9093 | 0.0076 | 0.0147 | 0.0066 | 0.0265 | 0.0199 | 0.0265 | 0.0939 | 0.1088 | 0.1319 | 0.1559 | 0.1717 | 0.1706 | 0.1063 | 0.0971 | 0.1395 | 0.1294 | 0.3226 | 0.2706 | 0.0007 | 0.0025 | 0.0074 | 0.0298 | 0.0895 | 0.1288 | 0.1057 | 0.1541 | 0.4816 | 12 | 14 | 17 | 23 | 43 | 88 | 167 | 264 | 387 | 0.0461 | 28.23 | 5.244 | 0.4903 | 51505.6 | 27300000 | 17700000000 | 13300000000000 | 0.5436 | 0.1197 | 0.0589 | 0.0037 | 0.2135 | 0.0134 | 0.3305 | 0.1158 | 0.1622 | 0.1818 | 0.0910 | 0.2308 | 0.0773 | 0.1922 | 0.0344 | 0.1091 | 0.0245 | 0.0820 | 0.0077 | 0.0712 | 0.0000 | 0.0004 | 0.0004 | 0.0007 | 0.0018 | 0.0016 | 0.0103 | 0.0074 | 0.0488 | 0.0426 | 0.0827 | 0.0744 | 0.0564 | 0.0488 | 0.0887 | 0.0770 | 0.7108 | 0.7471 | 0.0003 | 0.0002 | 0.0010 | 0.0013 | 0.0015 | 0.0013 | 0.0126 | 0.0158 | 0.0614 | 0.0710 | 0.1023 | 0.1142 | 0.0737 | 0.0805 | 0.1031 | 0.1182 | 0.6440 | 0.5975 | 0.0002 | 0.0003 | 0.0017 | 0.0124 | 0.0554 | 0.0907 | 0.0685 | 0.0965 | 0.6744 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 977 | 301 | | 13922 | 26863 | 211.1 | 59.41 | 243.85 | 302.54 | 140 | 161 | 177 | 191 | 205 | 221 | 237 | 258 | 290 | 0.0529 | 1421 | 0.517 | 152.46 | 33.12 | 3 | 0.0332 | 462 | 0.0010 | 40.05 | 7.158 | 0.1901 | 48082.9 | 11800000 | 3080000000 | 860000000000 | 0.4554 | 0.1927 | 0.0003 | 0.0000 | 0.0020 | 0.0002 | 0.0126 | 0.0010 | 0.0382 | 0.0033 | 0.1052 | 0.0256 | 0.1779 | 0.0652 | 0.1708 | 0.0702 | 0.1853 | 0.1080 | 0.3078 | 0.7265 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0019 | 0.0001 | 0.0091 | 0.0017 | 0.0405 | 0.0146 | 0.0746 | 0.0338 | 0.0714 | 0.0312 | 0.0998 | 0.0497 | 0.7024 | 0.8688 | 0.0033 | 0.0099 | 0.0092 | 0.0108 | 0.0191 | 0.0381 | 0.0654 | 0.1094 | 0.1325 | 0.1930 | 0.1822 | 0.1872 | 0.1190 | 0.0969 | 0.1457 | 0.1367 | 0.3236 | 0.2179 | 0.0009 | 0.0022 | 0.0066 | 0.0320 | 0.0904 | 0.1306 | 0.1036 | 0.1336 | 0.5001 | 8 | 10 | 14 | 35 | 97 | 203 | 327 | 486 | 702 | 0.0530 | 47.80 | 5.717 | 0.4211 | 150993.0 | 122000000 | 114000000000 | 121000000000000 | 0.4350 | 0.2316 | 0.0406 | 0.0021 | 0.1879 | 0.0150 | 0.2563 | 0.1084 | 0.1660 | 0.1540 | 0.1487 | 0.1826 | 0.0976 | 0.1847 | 0.0579 | 0.1280 | 0.0269 | 0.1004 | 0.0182 | 0.1248 | 0.0001 | 0.0000 | 0.0006 | 0.0003 | 0.0014 | 0.0012 | 0.0074 | 0.0074 | 0.0475 | 0.0377 | 0.0763 | 0.0659 | 0.0613 | 0.0479 | 0.0889 | 0.0735 | 0.7164 | 0.7660 | 0.0003 | 0.0001 | 0.0006 | 0.0004 | 0.0025 | 0.0033 | 0.0148 | 0.0202 | 0.0626 | 0.0746 | 0.1137 | 0.1211 | 0.0770 | 0.0770 | 0.1055 | 0.1172 | 0.6229 | 0.5861 | 0.0001 | 0.0008 | 0.0026 | 0.0105 | 0.0553 | 0.0925 | 0.0698 | 0.1031 | 0.6653 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 484 | 784 | | 7556 | 23389 | 282.7 | 59.70 | 166.78 | 196.60 | 210 | 231 | 247 | 262 | 276 | 293 | 311 | 334 | 366 | 0.0490 | 1145 | 1.213 | 102.16 | 38.05 | 1 | 0.0335 | 253 | 0.0006 | 75.57 | 7.614 | 0.1408 | 83467.9 | 25700000 | 8220000000 | 2730000000000 | 0.4316 | 0.2191 | 0.0002 | 0.0003 | 0.0006 | 0.0001 | 0.0020 | 0.0000 | 0.0170 | 0.0010 | 0.0677 | 0.0158 | 0.1511 | 0.0377 | 0.1521 | 0.0373 | 0.1708 | 0.0609 | 0.4384 | 0.8469 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0056 | 0.0004 | 0.0270 | 0.0106 | 0.0679 | 0.0232 | 0.0670 | 0.0160 | 0.0934 | 0.0265 | 0.7377 | 0.9233 | 0.0044 | 0.0233 | 0.0110 | 0.0233 | 0.0242 | 0.0631 | 0.0696 | 0.1728 | 0.1275 | 0.1960 | 0.1758 | 0.2060 | 0.1231 | 0.1063 | 0.1407 | 0.1296 | 0.3238 | 0.0797 | 0.0012 | 0.0035 | 0.0092 | 0.0372 | 0.0773 | 0.1330 | 0.1108 | 0.1304 | 0.4975 | 13 | 15 | 19 | 28 | 65 | 144 | 233 | 329 | 451 | 0.0382 | 38.04 | 5.638 | 0.4378 | 66466.3 | 34900000 | 21500000000 | 14900000000000 | 0.4729 | 0.1465 | 0.0850 | 0.0014 | 0.2309 | 0.0230 | 0.3225 | 0.1754 | 0.1274 | 0.1961 | 0.0928 | 0.2081 | 0.0531 | 0.1530 | 0.0330 | 0.0985 | 0.0279 | 0.0639 | 0.0274 | 0.0806 | 0.0000 | 0.0000 | 0.0005 | 0.0004 | 0.0009 | 0.0009 | 0.0084 | 0.0061 | 0.0473 | 0.0406 | 0.0840 | 0.0716 | 0.0667 | 0.0537 | 0.1009 | 0.0862 | 0.6912 | 0.7406 | 0.0001 | 0.0001 | 0.0013 | 0.0011 | 0.0031 | 0.0056 | 0.0161 | 0.0217 | 0.0677 | 0.0724 | 0.1058 | 0.1268 | 0.0903 | 0.0954 | 0.1290 | 0.1366 | 0.5867 | 0.5403 | 0.0000 | 0.0011 | 0.0013 | 0.0122 | 0.0536 | 0.0968 | 0.0807 | 0.1121 | 0.6423 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 592 | 492 | | 4236 | 12697 | 651.9 | 140.09 | 147.12 | 254.46 | 443 | 556 | 603 | 639 | 676 | 704 | 732 | 763 | 805 | 0.0784 | 995 | 1.202 | 120.07 | 45.18 | 3 | 0.0708 | 300 | 0.0015 | 22.93 | 6.808 | 0.2599 | 444572.0 | 313000000 | 227000000000 | 168000000000000 | 0.4044 | 0.2398 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0034 | 0.0003 | 0.0058 | 0.0021 | 0.0378 | 0.0206 | 0.0903 | 0.0398 | 0.0701 | 0.0247 | 0.1192 | 0.0367 | 0.6731 | 0.8759 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0003 | 0.0006 | 0.0013 | 0.0152 | 0.0187 | 0.0336 | 0.0329 | 0.0175 | 0.0152 | 0.0336 | 0.0255 | 0.8987 | 0.9062 | 0.0079 | 0.0000 | 0.0111 | 0.0154 | 0.0300 | 0.1385 | 0.0679 | 0.1385 | 0.1153 | 0.2308 | 0.1801 | 0.1846 | 0.1153 | 0.1385 | 0.1485 | 0.1231 | 0.3239 | 0.0308 | 0.0000 | 0.0017 | 0.0033 | 0.0079 | 0.0426 | 0.0857 | 0.0662 | 0.0919 | 0.7007 | 8 | 9 | 11 | 14 | 20 | 38 | 105 | 241 | 506 | 0.1619 | 33.70 | 4.314 | 0.6111 | 86390.9 | 71500000 | 69700000000 | 75500000000000 | 0.6018 | 0.0757 | 0.0644 | 0.0043 | 0.2356 | 0.0325 | 0.2932 | 0.1702 | 0.1458 | 0.1856 | 0.1136 | 0.2002 | 0.0661 | 0.1856 | 0.0373 | 0.0821 | 0.0305 | 0.0736 | 0.0136 | 0.0659 | 0.0000 | 0.0003 | 0.0014 | 0.0000 | 0.0005 | 0.0025 | 0.0096 | 0.0093 | 0.0536 | 0.0496 | 0.1026 | 0.0981 | 0.0517 | 0.0496 | 0.0780 | 0.0733 | 0.7027 | 0.7174 | 0.0003 | 0.0007 | 0.0013 | 0.0004 | 0.0023 | 0.0011 | 0.0134 | 0.0173 | 0.0623 | 0.0665 | 0.1086 | 0.1122 | 0.0633 | 0.0725 | 0.0939 | 0.0952 | 0.6546 | 0.6341 | 0.0000 | 0.0012 | 0.0024 | 0.0150 | 0.0559 | 0.1057 | 0.0574 | 0.0811 | 0.6813 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 819 | 837 | | 4077 | 7402 | 164.0 | 45.49 | 281.51 | 208.60 | 106 | 126 | 139 | 150 | 161 | 172 | 185 | 201 | 225 | 0.0809 | 599 | 0.666 | 68.59 | 22.56 | 2 | 0.0518 | 211 | 0.0013 | 30.19 | 6.879 | 0.2104 | 28976.0 | 5470000 | 1100000000 | 232000000000 | 0.4785 | 0.1795 | 0.0028 | 0.0000 | 0.0032 | 0.0006 | 0.0065 | 0.0020 | 0.0341 | 0.0061 | 0.1138 | 0.0314 | 0.1876 | 0.0802 | 0.1618 | 0.0709 | 0.1834 | 0.0994 | 0.3069 | 0.7095 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0019 | 0.0005 | 0.0081 | 0.0026 | 0.0430 | 0.0195 | 0.0783 | 0.0445 | 0.0608 | 0.0306 | 0.0935 | 0.0458 | 0.7126 | 0.8562 | 0.0043 | 0.0113 | 0.0185 | 0.0226 | 0.0120 | 0.0452 | 0.0663 | 0.1271 | 0.1261 | 0.1582 | 0.1815 | 0.2345 | 0.1239 | 0.1356 | 0.1424 | 0.0989 | 0.3250 | 0.1667 | 0.0015 | 0.0021 | 0.0072 | 0.0355 | 0.0762 | 0.1340 | 0.1061 | 0.1175 | 0.5198 | 41 | 86 | 136 | 190 | 247 | 308 | 370 | 448 | 564 | 0.0018 | 128.90 | 7.431 | 0.1991 | 122752.0 | 67400000 | 43400000000 | 31600000000000 | 0.5494 | 0.1250 | 0.0218 | 0.0004 | 0.1102 | 0.0047 | 0.2408 | 0.0505 | 0.1748 | 0.0920 | 0.1769 | 0.1749 | 0.1363 | 0.2080 | 0.0798 | 0.1531 | 0.0428 | 0.1385 | 0.0167 | 0.1778 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0011 | 0.0151 | 0.0089 | 0.0627 | 0.0498 | 0.1204 | 0.0924 | 0.0929 | 0.0759 | 0.1327 | 0.1043 | 0.5715 | 0.6676 | 0.0000 | 0.0020 | 0.0042 | 0.0036 | 0.0096 | 0.0137 | 0.0301 | 0.0493 | 0.1131 | 0.1301 | 0.1521 | 0.1876 | 0.1212 | 0.1256 | 0.1613 | 0.1520 | 0.4083 | 0.3360 | 0.0015 | 0.0024 | 0.0049 | 0.0182 | 0.0809 | 0.1469 | 0.1031 | 0.1338 | 0.5082 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 735 | 634 | | 3383 | 13602 | 420.5 | 93.73 | 24.16 | 65.07 | 310 | 345 | 369 | 393 | 413 | 435 | 458 | 483 | 531 | 0.0471 | 641 | 0.708 | 187.75 | 42.58 | 1 | 0.1469 | 497 | 0.0008 | 81.64 | 7.362 | 0.1445 | 185607.0 | 86200000 | 42200000000 | 21900000000000 | 0.4414 | 0.2109 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0000 | 0.0190 | 0.0000 | 0.0557 | 0.0201 | 0.1348 | 0.0447 | 0.1232 | 0.0352 | 0.1517 | 0.0569 | 0.5108 | 0.8430 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0061 | 0.0000 | 0.0327 | 0.0138 | 0.0779 | 0.0312 | 0.0610 | 0.0204 | 0.0832 | 0.0309 | 0.7391 | 0.9038 | 0.0169 | 0.0000 | 0.0127 | 0.0252 | 0.0465 | 0.0377 | 0.0465 | 0.0755 | 0.1269 | 0.1447 | 0.1882 | 0.1698 | 0.0867 | 0.1195 | 0.1501 | 0.1069 | 0.3256 | 0.3208 | 0.0000 | 0.0050 | 0.0126 | 0.0320 | 0.0961 | 0.1420 | 0.1030 | 0.1470 | 0.4623 | 5 | 6 | 7 | 7 | 9 | 10 | 13 | 19 | 43 | 0.1856 | 1.96 | 2.069 | 0.6343 | 4817.1 | 2540000 | 1750000000 | 1330000000000 | 0.5397 | 0.1164 | 0.0580 | 0.0279 | 0.1116 | 0.0343 | 0.1949 | 0.0594 | 0.2024 | 0.1054 | 0.1741 | 0.1577 | 0.1310 | 0.1758 | 0.0759 | 0.1589 | 0.0387 | 0.1368 | 0.0134 | 0.1438 | 0.0052 | 0.0139 | 0.0041 | 0.0154 | 0.0067 | 0.0198 | 0.0191 | 0.0302 | 0.0479 | 0.0395 | 0.0621 | 0.0552 | 0.0592 | 0.0599 | 0.0943 | 0.0738 | 0.7012 | 0.6922 | 0.0010 | 0.0012 | 0.0035 | 0.0035 | 0.0045 | 0.0104 | 0.0205 | 0.0267 | 0.0730 | 0.0818 | 0.0985 | 0.1021 | 0.0725 | 0.0754 | 0.1151 | 0.1155 | 0.6113 | 0.5833 | 0.0026 | 0.0039 | 0.0039 | 0.0176 | 0.0511 | 0.0815 | 0.0686 | 0.1047 | 0.6662 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 508 | 133 | | 5112 | 15953 | 596.9 | 122.93 | 209.99 | 332.25 | 447 | 490 | 521 | 552 | 585 | 617 | 653 | 698 | 767 | 0.0564 | 899 | 0.855 | 86.15 | 24.76 | 1 | 0.0428 | 219 | 0.0004 | 156.57 | 7.925 | 0.1053 | 371349.0 | 241000000 | 162000000000 | 113000000000000 | 0.4423 | 0.2051 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0187 | 0.0008 | 0.0672 | 0.0192 | 0.1466 | 0.0410 | 0.1398 | 0.0373 | 0.1694 | 0.0551 | 0.4551 | 0.8466 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0089 | 0.0004 | 0.0325 | 0.0132 | 0.0678 | 0.0246 | 0.0610 | 0.0151 | 0.0909 | 0.0305 | 0.7386 | 0.9162 | 0.0023 | 0.0043 | 0.0103 | 0.0043 | 0.0195 | 0.0468 | 0.0736 | 0.1319 | 0.1310 | 0.1872 | 0.2080 | 0.2468 | 0.1023 | 0.0936 | 0.1264 | 0.1106 | 0.3264 | 0.1745 | 0.0008 | 0.0025 | 0.0105 | 0.0257 | 0.0758 | 0.1281 | 0.1049 | 0.1184 | 0.5333 | 8 | 10 | 12 | 14 | 20 | 73 | 208 | 417 | 696 | 0.1770 | 37.47 | 4.561 | 0.5961 | 154477.0 | 156000000 | 189000000000 | 260000000000000 | 0.5567 | 0.1171 | 0.0435 | 0.0017 | 0.1317 | 0.0133 | 0.1719 | 0.0920 | 0.1462 | 0.1123 | 0.1551 | 0.1516 | 0.1272 | 0.1707 | 0.1071 | 0.1244 | 0.0737 | 0.1291 | 0.0435 | 0.2049 | 0.0000 | 0.0003 | 0.0002 | 0.0000 | 0.0013 | 0.0010 | 0.0089 | 0.0045 | 0.0312 | 0.0322 | 0.0618 | 0.0501 | 0.0532 | 0.0353 | 0.0709 | 0.0694 | 0.7724 | 0.8070 | 0.0005 | 0.0002 | 0.0000 | 0.0007 | 0.0023 | 0.0015 | 0.0087 | 0.0100 | 0.0449 | 0.0500 | 0.0795 | 0.0826 | 0.0525 | 0.0585 | 0.0887 | 0.0933 | 0.7230 | 0.7032 | 0.0008 | 0.0015 | 0.0023 | 0.0088 | 0.0390 | 0.0736 | 0.0524 | 0.0793 | 0.7423 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 662 | 697 | | 5913 | 18261 | 491.0 | 67.94 | 138.35 | 220.58 | 396 | 436 | 462 | 484 | 500 | 513 | 528 | 544 | 572 | 0.0451 | 824 | 1.176 | 94.54 | 34.99 | 1 | 0.0404 | 239 | 0.0021 | 16.68 | 6.549 | 0.2788 | 245703.0 | 125000000 | 64600000000 | 33900000000000 | 0.4193 | 0.2254 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0002 | 0.0206 | 0.0107 | 0.0401 | 0.0231 | 0.0409 | 0.0105 | 0.0497 | 0.0178 | 0.8421 | 0.9378 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0011 | 0.0002 | 0.0140 | 0.0105 | 0.0257 | 0.0222 | 0.0200 | 0.0095 | 0.0276 | 0.0162 | 0.9112 | 0.9414 | 0.0028 | 0.0000 | 0.0142 | 0.1111 | 0.0426 | 0.1111 | 0.0767 | 0.1111 | 0.1392 | 0.4444 | 0.1193 | 0.2222 | 0.1193 | 0.0000 | 0.1591 | 0.0000 | 0.3267 | 0.0000 | 0.0003 | 0.0033 | 0.0069 | 0.0169 | 0.0350 | 0.0555 | 0.0628 | 0.0872 | 0.7320 | 8 | 10 | 12 | 16 | 27 | 52 | 112 | 246 | 464 | 0.1339 | 21.44 | 4.364 | 0.6125 | 67793.0 | 46900000 | 38600000000 | 36000000000000 | 0.3682 | 0.2671 | 0.0646 | 0.0035 | 0.1579 | 0.0234 | 0.2759 | 0.1034 | 0.1692 | 0.1313 | 0.1344 | 0.1895 | 0.0985 | 0.2004 | 0.0595 | 0.1034 | 0.0236 | 0.1193 | 0.0164 | 0.1258 | 0.0004 | 0.0006 | 0.0011 | 0.0015 | 0.0025 | 0.0023 | 0.0114 | 0.0085 | 0.0461 | 0.0447 | 0.0764 | 0.0614 | 0.0517 | 0.0432 | 0.0719 | 0.0705 | 0.7384 | 0.7673 | 0.0011 | 0.0005 | 0.0009 | 0.0007 | 0.0026 | 0.0033 | 0.0168 | 0.0158 | 0.0521 | 0.0575 | 0.0907 | 0.0945 | 0.0618 | 0.0628 | 0.0783 | 0.0833 | 0.6958 | 0.6816 | 0.0006 | 0.0014 | 0.0028 | 0.0152 | 0.0474 | 0.0861 | 0.0548 | 0.0734 | 0.7183 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 951 | 130 | | 6472 | 11634 | 104.2 | 26.74 | 134.36 | 144.55 | 75 | 82 | 88 | 93 | 99 | 106 | 114 | 124 | 140 | 0.0675 | 785 | 1.222 | 77.80 | 31.00 | 1 | 0.0311 | 201 | 0.0033 | 14.98 | 6.074 | 0.2909 | 11575.5 | 1380000 | 176000000 | 24100000000 | 0.4404 | 0.2109 | 0.0008 | 0.0000 | 0.0067 | 0.0000 | 0.0180 | 0.0003 | 0.0355 | 0.0049 | 0.0968 | 0.0225 | 0.1552 | 0.0473 | 0.1791 | 0.0458 | 0.2071 | 0.0729 | 0.3007 | 0.8063 | 0.0002 | 0.0000 | 0.0028 | 0.0000 | 0.0058 | 0.0002 | 0.0154 | 0.0008 | 0.0436 | 0.0128 | 0.0690 | 0.0233 | 0.0790 | 0.0166 | 0.1135 | 0.0378 | 0.6708 | 0.9086 | 0.0078 | 0.0060 | 0.0132 | 0.0302 | 0.0296 | 0.0302 | 0.0685 | 0.0867 | 0.1401 | 0.1512 | 0.1556 | 0.2198 | 0.1222 | 0.1109 | 0.1362 | 0.1431 | 0.3268 | 0.2218 | 0.0014 | 0.0074 | 0.0159 | 0.0337 | 0.0708 | 0.1173 | 0.1045 | 0.1399 | 0.5090 | 11 | 17 | 27 | 47 | 80 | 123 | 170 | 236 | 349 | 0.0095 | 68.36 | 6.495 | 0.3320 | 38946.3 | 15400000 | 7190000000 | 3780000000000 | 0.5106 | 0.1580 | 0.0359 | 0.0011 | 0.1272 | 0.0129 | 0.2289 | 0.0620 | 0.1945 | 0.1073 | 0.1660 | 0.1675 | 0.1137 | 0.2080 | 0.0666 | 0.1442 | 0.0449 | 0.1357 | 0.0224 | 0.1612 | 0.0002 | 0.0000 | 0.0004 | 0.0005 | 0.0036 | 0.0015 | 0.0120 | 0.0079 | 0.0557 | 0.0459 | 0.0946 | 0.0834 | 0.0802 | 0.0594 | 0.1058 | 0.0943 | 0.6476 | 0.7070 | 0.0003 | 0.0013 | 0.0024 | 0.0032 | 0.0089 | 0.0084 | 0.0282 | 0.0316 | 0.0805 | 0.0832 | 0.1194 | 0.1342 | 0.0982 | 0.1048 | 0.1210 | 0.1303 | 0.5413 | 0.5031 | 0.0002 | 0.0014 | 0.0041 | 0.0182 | 0.0668 | 0.1165 | 0.0832 | 0.1178 | 0.5918 | ||
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1040 | 910 | | 3585 | 10231 | 344.3 | 84.59 | 34.10 | 76.86 | 243 | 270 | 294 | 317 | 338 | 360 | 384 | 412 | 458 | 0.0777 | 795 | 0.975 | 80.16 | 26.08 | 1 | 0.0555 | 199 | 0.0010 | 48.18 | 7.091 | 0.1715 | 125705.0 | 48500000 | 19700000000 | 8380000000000 | 0.4417 | 0.2214 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0058 | 0.0006 | 0.0346 | 0.0056 | 0.1029 | 0.0262 | 0.1587 | 0.0586 | 0.1640 | 0.0586 | 0.1722 | 0.0873 | 0.3583 | 0.7630 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0014 | 0.0006 | 0.0122 | 0.0029 | 0.0480 | 0.0161 | 0.0735 | 0.0365 | 0.0724 | 0.0276 | 0.0882 | 0.0419 | 0.7031 | 0.8745 | 0.0056 | 0.0041 | 0.0014 | 0.0331 | 0.0324 | 0.0455 | 0.0606 | 0.0909 | 0.1437 | 0.2066 | 0.1521 | 0.1901 | 0.1211 | 0.1116 | 0.1563 | 0.1570 | 0.3268 | 0.1612 | 0.0006 | 0.0041 | 0.0094 | 0.0241 | 0.0700 | 0.1329 | 0.0988 | 0.1424 | 0.5176 | 5 | 6 | 6 | 8 | 9 | 10 | 14 | 28 | 84 | 0.2835 | 3.77 | 2.562 | 0.7553 | 7069.4 | 2850000 | 1600000000 | 1100000000000 | 0.6411 | 0.0755 | 0.0751 | 0.0073 | 0.1503 | 0.0125 | 0.2306 | 0.0658 | 0.2098 | 0.1524 | 0.1710 | 0.1994 | 0.0984 | 0.1754 | 0.0492 | 0.1242 | 0.0130 | 0.1420 | 0.0026 | 0.1211 | 0.0063 | 0.0020 | 0.0073 | 0.0041 | 0.0078 | 0.0138 | 0.0195 | 0.0292 | 0.0640 | 0.0604 | 0.0762 | 0.0835 | 0.0703 | 0.0722 | 0.0996 | 0.1078 | 0.6489 | 0.6271 | 0.0012 | 0.0040 | 0.0030 | 0.0020 | 0.0084 | 0.0080 | 0.0247 | 0.0172 | 0.0596 | 0.0669 | 0.0915 | 0.0948 | 0.0686 | 0.0749 | 0.1113 | 0.1021 | 0.6318 | 0.6302 | 0.0027 | 0.0027 | 0.0092 | 0.0223 | 0.0566 | 0.0886 | 0.0691 | 0.1033 | 0.6455 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 976 | 627 | | 9507 | 15770 | 172.7 | 40.39 | 150.51 | 142.96 | 124 | 138 | 148 | 159 | 169 | 180 | 192 | 205 | 226 | 0.0652 | 1028 | 0.252 | 178.21 | 38.29 | 2 | 0.0807 | 767 | 0.0013 | 30.28 | 6.953 | 0.2069 | 31455.3 | 6030000 | 1210000000 | 255000000000 | 0.4791 | 0.1735 | 0.0005 | 0.0001 | 0.0012 | 0.0000 | 0.0054 | 0.0005 | 0.0209 | 0.0019 | 0.0790 | 0.0197 | 0.1482 | 0.0402 | 0.1609 | 0.0520 | 0.1854 | 0.0737 | 0.3985 | 0.8119 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0027 | 0.0001 | 0.0082 | 0.0004 | 0.0356 | 0.0131 | 0.0592 | 0.0224 | 0.0625 | 0.0227 | 0.0860 | 0.0360 | 0.7450 | 0.9053 | 0.0072 | 0.0075 | 0.0078 | 0.0226 | 0.0245 | 0.0395 | 0.0686 | 0.1598 | 0.1421 | 0.1692 | 0.1633 | 0.1805 | 0.1165 | 0.1297 | 0.1427 | 0.1147 | 0.3272 | 0.1767 | 0.0011 | 0.0022 | 0.0101 | 0.0314 | 0.0686 | 0.1188 | 0.1000 | 0.1331 | 0.5347 | 15 | 26 | 47 | 75 | 109 | 150 | 195 | 249 | 346 | 0.0111 | 36.23 | 6.317 | 0.3622 | 43089.9 | 16900000 | 8150000000 | 4520000000000 | 0.5500 | 0.1433 | 0.0300 | 0.0027 | 0.1203 | 0.0089 | 0.2106 | 0.0533 | 0.1413 | 0.1064 | 0.1498 | 0.1689 | 0.1341 | 0.1813 | 0.0903 | 0.1371 | 0.0662 | 0.1320 | 0.0577 | 0.2093 | 0.0005 | 0.0010 | 0.0013 | 0.0013 | 0.0051 | 0.0033 | 0.0142 | 0.0094 | 0.0556 | 0.0503 | 0.0990 | 0.0768 | 0.0770 | 0.0661 | 0.1045 | 0.0926 | 0.6428 | 0.6991 | 0.0008 | 0.0021 | 0.0025 | 0.0062 | 0.0081 | 0.0129 | 0.0272 | 0.0348 | 0.0805 | 0.0881 | 0.1303 | 0.1407 | 0.0956 | 0.1050 | 0.1222 | 0.1264 | 0.5327 | 0.4839 | 0.0003 | 0.0032 | 0.0054 | 0.0167 | 0.0715 | 0.1122 | 0.0858 | 0.1157 | 0.5891 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 141 | 279 | | 6550 | 28560 | 325.2 | 76.94 | 118.00 | 205.38 | 229 | 259 | 281 | 299 | 318 | 339 | 361 | 391 | 431 | 0.0380 | 1086 | 1.019 | 88.10 | 26.68 | 3 | 0.0337 | 221 | 0.0007 | 63.80 | 7.487 | 0.1467 | 111704.0 | 40400000 | 15300000000 | 6070000000000 | 0.4422 | 0.2121 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0067 | 0.0012 | 0.0248 | 0.0030 | 0.0781 | 0.0206 | 0.1554 | 0.0495 | 0.1682 | 0.0513 | 0.1992 | 0.0834 | 0.3659 | 0.7909 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0003 | 0.0069 | 0.0006 | 0.0339 | 0.0127 | 0.0714 | 0.0286 | 0.0678 | 0.0219 | 0.0992 | 0.0413 | 0.7200 | 0.8945 | 0.0053 | 0.0096 | 0.0114 | 0.0288 | 0.0220 | 0.0745 | 0.0676 | 0.0962 | 0.1277 | 0.1923 | 0.1634 | 0.1635 | 0.1087 | 0.1130 | 0.1664 | 0.1394 | 0.3275 | 0.1827 | 0.0010 | 0.0043 | 0.0085 | 0.0299 | 0.0768 | 0.1404 | 0.1063 | 0.1358 | 0.4970 | 7 | 9 | 10 | 12 | 16 | 29 | 83 | 200 | 398 | 0.1579 | 24.15 | 4.168 | 0.5959 | 56105.0 | 38900000 | 32800000000 | 31500000000000 | 0.4719 | 0.1982 | 0.0778 | 0.0031 | 0.2645 | 0.0291 | 0.3497 | 0.1507 | 0.1482 | 0.1884 | 0.0819 | 0.2342 | 0.0426 | 0.1740 | 0.0180 | 0.0983 | 0.0098 | 0.0746 | 0.0074 | 0.0478 | 0.0000 | 0.0001 | 0.0004 | 0.0002 | 0.0004 | 0.0003 | 0.0067 | 0.0067 | 0.0467 | 0.0397 | 0.0880 | 0.0720 | 0.0536 | 0.0512 | 0.0899 | 0.0787 | 0.7143 | 0.7511 | 0.0001 | 0.0003 | 0.0004 | 0.0012 | 0.0016 | 0.0016 | 0.0092 | 0.0145 | 0.0557 | 0.0597 | 0.1096 | 0.1123 | 0.0663 | 0.0794 | 0.1060 | 0.1115 | 0.6510 | 0.6194 | 0.0000 | 0.0001 | 0.0019 | 0.0094 | 0.0525 | 0.0917 | 0.0654 | 0.0947 | 0.6842 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1182 | 506 | | 5215 | 17071 | 251.9 | 54.05 | 103.06 | 163.53 | 180 | 201 | 217 | 233 | 250 | 266 | 282 | 302 | 327 | 0.0592 | 1011 | 1.075 | 113.14 | 33.02 | 1 | 0.0516 | 269 | 0.0008 | 48.54 | 7.272 | 0.1797 | 66392.4 | 18200000 | 5190000000 | 1520000000000 | 0.4330 | 0.2117 | 0.0006 | 0.0000 | 0.0022 | 0.0000 | 0.0048 | 0.0000 | 0.0275 | 0.0022 | 0.0797 | 0.0138 | 0.1232 | 0.0367 | 0.1331 | 0.0359 | 0.1574 | 0.0648 | 0.4715 | 0.8468 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0077 | 0.0012 | 0.0289 | 0.0106 | 0.0534 | 0.0245 | 0.0530 | 0.0168 | 0.0732 | 0.0315 | 0.7817 | 0.9154 | 0.0029 | 0.0373 | 0.0097 | 0.0683 | 0.0165 | 0.0683 | 0.0584 | 0.1739 | 0.1051 | 0.2050 | 0.1907 | 0.1801 | 0.1430 | 0.1180 | 0.1459 | 0.0745 | 0.3278 | 0.0745 | 0.0004 | 0.0027 | 0.0059 | 0.0212 | 0.0550 | 0.1037 | 0.0923 | 0.1127 | 0.6060 | 8 | 10 | 12 | 14 | 19 | 40 | 88 | 178 | 323 | 0.1315 | 17.54 | 4.370 | 0.5904 | 37361.8 | 20200000 | 13400000000 | 10300000000000 | 0.5718 | 0.1052 | 0.0904 | 0.0025 | 0.2461 | 0.0286 | 0.3176 | 0.1880 | 0.1451 | 0.1835 | 0.0925 | 0.1830 | 0.0641 | 0.1810 | 0.0273 | 0.0847 | 0.0137 | 0.0762 | 0.0032 | 0.0727 | 0.0004 | 0.0000 | 0.0008 | 0.0005 | 0.0013 | 0.0015 | 0.0144 | 0.0131 | 0.0649 | 0.0555 | 0.1011 | 0.0975 | 0.0663 | 0.0604 | 0.0930 | 0.0903 | 0.6578 | 0.6812 | 0.0005 | 0.0005 | 0.0016 | 0.0020 | 0.0060 | 0.0048 | 0.0196 | 0.0218 | 0.0670 | 0.0698 | 0.1097 | 0.1043 | 0.0649 | 0.0698 | 0.0947 | 0.0959 | 0.6360 | 0.6311 | 0.0004 | 0.0010 | 0.0042 | 0.0151 | 0.0692 | 0.1025 | 0.0681 | 0.0903 | 0.6491 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 156 | 594 | | 9080 | 15618 | 311.0 | 68.29 | 98.46 | 121.64 | 229 | 251 | 270 | 288 | 305 | 324 | 344 | 367 | 401 | 0.0788 | 1231 | 0.960 | 135.72 | 35.01 | 1 | 0.0352 | 320 | 0.0013 | 28.86 | 6.929 | 0.2122 | 101409.0 | 34600000 | 12300000000 | 4590000000000 | 0.4537 | 0.2035 | 0.0010 | 0.0000 | 0.0019 | 0.0001 | 0.0068 | 0.0009 | 0.0222 | 0.0025 | 0.0705 | 0.0167 | 0.1362 | 0.0410 | 0.1452 | 0.0416 | 0.1613 | 0.0640 | 0.4548 | 0.8331 | 0.0007 | 0.0000 | 0.0005 | 0.0000 | 0.0027 | 0.0006 | 0.0099 | 0.0020 | 0.0293 | 0.0115 | 0.0662 | 0.0283 | 0.0633 | 0.0223 | 0.0823 | 0.0364 | 0.7452 | 0.8989 | 0.0056 | 0.0027 | 0.0124 | 0.0318 | 0.0204 | 0.0637 | 0.0667 | 0.1141 | 0.1248 | 0.2042 | 0.1513 | 0.1485 | 0.1328 | 0.0716 | 0.1575 | 0.1300 | 0.3286 | 0.2334 | 0.0007 | 0.0030 | 0.0096 | 0.0287 | 0.0674 | 0.1168 | 0.1070 | 0.1261 | 0.5408 | 12 | 14 | 17 | 23 | 41 | 74 | 118 | 173 | 260 | 0.0390 | 25.52 | 5.297 | 0.4490 | 24490.2 | 9030000 | 4150000000 | 2200000000000 | 0.5460 | 0.1292 | 0.0690 | 0.0018 | 0.1999 | 0.0187 | 0.2994 | 0.1257 | 0.1613 | 0.1617 | 0.1323 | 0.2185 | 0.0814 | 0.1892 | 0.0378 | 0.1186 | 0.0145 | 0.0981 | 0.0044 | 0.0678 | 0.0002 | 0.0003 | 0.0012 | 0.0006 | 0.0031 | 0.0027 | 0.0151 | 0.0124 | 0.0691 | 0.0593 | 0.1090 | 0.0934 | 0.0785 | 0.0690 | 0.1141 | 0.1000 | 0.6096 | 0.6622 | 0.0011 | 0.0015 | 0.0023 | 0.0025 | 0.0079 | 0.0093 | 0.0234 | 0.0284 | 0.0888 | 0.0944 | 0.1239 | 0.1444 | 0.0960 | 0.0946 | 0.1298 | 0.1284 | 0.5268 | 0.4966 | 0.0002 | 0.0022 | 0.0039 | 0.0202 | 0.0788 | 0.1208 | 0.0884 | 0.1238 | 0.5618 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 789 | 385 | | 5318 | 5252 | 117.1 | 28.29 | 183.50 | 149.81 | 88 | 95 | 101 | 106 | 111 | 118 | 126 | 135 | 153 | 0.1359 | 714 | 1.185 | 99.25 | 31.11 | 1 | 0.0440 | 234 | 0.0038 | 12.98 | 5.962 | 0.3134 | 14501.7 | 1920000 | 277000000 | 44100000000 | 0.4157 | 0.2302 | 0.0009 | 0.0000 | 0.0020 | 0.0000 | 0.0054 | 0.0000 | 0.0148 | 0.0014 | 0.0594 | 0.0200 | 0.1213 | 0.0451 | 0.1410 | 0.0401 | 0.1627 | 0.0615 | 0.4926 | 0.8319 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0032 | 0.0000 | 0.0092 | 0.0002 | 0.0304 | 0.0127 | 0.0533 | 0.0251 | 0.0612 | 0.0134 | 0.0839 | 0.0215 | 0.7570 | 0.9271 | 0.0036 | 0.0085 | 0.0107 | 0.0142 | 0.0130 | 0.0342 | 0.0627 | 0.0883 | 0.1456 | 0.2023 | 0.1692 | 0.1766 | 0.0994 | 0.0855 | 0.1669 | 0.1595 | 0.3290 | 0.2308 | 0.0013 | 0.0072 | 0.0103 | 0.0354 | 0.0752 | 0.1150 | 0.1115 | 0.1352 | 0.5090 | 34 | 56 | 79 | 108 | 140 | 180 | 233 | 298 | 398 | 0.0028 | 51.84 | 6.696 | 0.3006 | 56111.0 | 22900000 | 11200000000 | 6260000000000 | 0.5751 | 0.1077 | 0.0275 | 0.0017 | 0.1066 | 0.0098 | 0.2575 | 0.0574 | 0.1760 | 0.1074 | 0.1701 | 0.1895 | 0.1401 | 0.1959 | 0.0671 | 0.1430 | 0.0299 | 0.1310 | 0.0251 | 0.1643 | 0.0008 | 0.0000 | 0.0024 | 0.0010 | 0.0052 | 0.0029 | 0.0226 | 0.0226 | 0.0755 | 0.0634 | 0.1156 | 0.0976 | 0.0898 | 0.0789 | 0.1017 | 0.0957 | 0.5866 | 0.6379 | 0.0012 | 0.0007 | 0.0024 | 0.0052 | 0.0125 | 0.0163 | 0.0458 | 0.0570 | 0.0903 | 0.1117 | 0.1729 | 0.1805 | 0.1028 | 0.1139 | 0.1147 | 0.1220 | 0.4575 | 0.3928 | 0.0005 | 0.0044 | 0.0068 | 0.0311 | 0.0856 | 0.1465 | 0.0934 | 0.1226 | 0.5090 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1075 | 895 | | 4118 | 4934 | 145.3 | 36.15 | 206.60 | 178.21 | 103 | 116 | 125 | 133 | 141 | 149 | 158 | 171 | 192 | 0.1336 | 659 | 0.978 | 89.59 | 26.42 | 1 | 0.0529 | 218 | 0.0019 | 27.36 | 6.598 | 0.2315 | 22405.4 | 3670000 | 641000000 | 119000000000 | 0.4147 | 0.2407 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0093 | 0.0003 | 0.0201 | 0.0030 | 0.0872 | 0.0280 | 0.1515 | 0.0560 | 0.1519 | 0.0633 | 0.1709 | 0.0810 | 0.4076 | 0.7684 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0060 | 0.0007 | 0.0400 | 0.0177 | 0.0771 | 0.0337 | 0.0689 | 0.0327 | 0.0915 | 0.0434 | 0.7140 | 0.8718 | 0.0013 | 0.0068 | 0.0067 | 0.0136 | 0.0324 | 0.0306 | 0.0931 | 0.1054 | 0.1242 | 0.1667 | 0.1768 | 0.1939 | 0.1188 | 0.1224 | 0.1174 | 0.1361 | 0.3293 | 0.2245 | 0.0005 | 0.0037 | 0.0095 | 0.0349 | 0.1138 | 0.1376 | 0.1027 | 0.1466 | 0.4505 | 24 | 53 | 88 | 122 | 160 | 204 | 256 | 333 | 460 | 0.0021 | 74.59 | 7.103 | 0.2341 | 74435.4 | 36000000 | 21000000000 | 13800000000000 | 0.4404 | 0.2138 | 0.0141 | 0.0018 | 0.0633 | 0.0084 | 0.1547 | 0.0349 | 0.1864 | 0.0699 | 0.1934 | 0.1470 | 0.1536 | 0.1946 | 0.1313 | 0.1524 | 0.0610 | 0.1837 | 0.0422 | 0.2072 | 0.0012 | 0.0003 | 0.0033 | 0.0024 | 0.0067 | 0.0058 | 0.0158 | 0.0151 | 0.0596 | 0.0599 | 0.0979 | 0.0767 | 0.0870 | 0.0712 | 0.1083 | 0.1070 | 0.6202 | 0.6615 | 0.0013 | 0.0024 | 0.0071 | 0.0040 | 0.0110 | 0.0176 | 0.0323 | 0.0353 | 0.0788 | 0.0842 | 0.1072 | 0.1259 | 0.0969 | 0.0874 | 0.1111 | 0.1115 | 0.5543 | 0.5317 | 0.0026 | 0.0026 | 0.0067 | 0.0231 | 0.0817 | 0.0966 | 0.0910 | 0.1182 | 0.5776 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 170 | 550 | | 8750 | 8424 | 502.4 | 87.96 | 41.36 | 73.23 | 382 | 421 | 449 | 477 | 504 | 533 | 561 | 587 | 616 | 0.0991 | 835 | 0.776 | 84.48 | 24.52 | 5 | 0.0277 | 242 | 0.0010 | 31.96 | 7.187 | 0.2170 | 260103.0 | 138000000 | 75400000000 | 41900000000000 | 0.4172 | 0.2234 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0032 | 0.0000 | 0.0111 | 0.0005 | 0.0476 | 0.0114 | 0.0760 | 0.0187 | 0.0904 | 0.0131 | 0.1317 | 0.0244 | 0.6373 | 0.9319 | 0.0003 | 0.0000 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0005 | 0.0214 | 0.0113 | 0.0331 | 0.0183 | 0.0365 | 0.0119 | 0.0525 | 0.0214 | 0.8509 | 0.9367 | 0.0126 | 0.1000 | 0.0126 | 0.2000 | 0.0356 | 0.5000 | 0.0617 | 0.2000 | 0.1146 | 0.0000 | 0.1486 | 0.0000 | 0.1328 | 0.0000 | 0.1518 | 0.0000 | 0.3296 | 0.0000 | 0.0014 | 0.0023 | 0.0063 | 0.0160 | 0.0405 | 0.0657 | 0.0673 | 0.0822 | 0.7184 | 8 | 10 | 12 | 13 | 16 | 20 | 28 | 44 | 98 | 0.1584 | 2.61 | 3.052 | 0.7597 | 7073.0 | 2420000 | 1080000000 | 547000000000 | 0.6438 | 0.0750 | 0.0266 | 0.0119 | 0.0620 | 0.0252 | 0.1004 | 0.0365 | 0.1492 | 0.0697 | 0.1905 | 0.1048 | 0.1418 | 0.1287 | 0.1536 | 0.1301 | 0.0960 | 0.1858 | 0.0798 | 0.3072 | 0.0055 | 0.0063 | 0.0104 | 0.0116 | 0.0127 | 0.0137 | 0.0209 | 0.0256 | 0.0563 | 0.0460 | 0.0700 | 0.0674 | 0.0691 | 0.0593 | 0.1004 | 0.1092 | 0.6547 | 0.6608 | 0.0000 | 0.0045 | 0.0052 | 0.0037 | 0.0085 | 0.0082 | 0.0184 | 0.0231 | 0.0636 | 0.0723 | 0.0932 | 0.0835 | 0.0636 | 0.0776 | 0.1122 | 0.1148 | 0.6352 | 0.6122 | 0.0011 | 0.0038 | 0.0098 | 0.0235 | 0.0573 | 0.0742 | 0.0770 | 0.1070 | 0.6463 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 541 | 522 | | 7538 | 10729 | 182.1 | 53.16 | 151.55 | 105.15 | 123 | 138 | 150 | 162 | 173 | 185 | 200 | 220 | 253 | 0.0842 | 903 | 1.033 | 124.56 | 28.32 | 1 | 0.0358 | 270 | 0.0011 | 47.33 | 7.166 | 0.1859 | 35971.8 | 7740000 | 1820000000 | 464000000000 | 0.4607 | 0.1986 | 0.0008 | 0.0002 | 0.0033 | 0.0003 | 0.0110 | 0.0014 | 0.0358 | 0.0038 | 0.1099 | 0.0259 | 0.1983 | 0.0649 | 0.1693 | 0.0640 | 0.1888 | 0.0978 | 0.2827 | 0.7419 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0075 | 0.0010 | 0.0464 | 0.0143 | 0.0907 | 0.0329 | 0.0762 | 0.0285 | 0.1180 | 0.0474 | 0.6588 | 0.8759 | 0.0038 | 0.0055 | 0.0070 | 0.0083 | 0.0203 | 0.0290 | 0.0725 | 0.0981 | 0.1462 | 0.1630 | 0.1697 | 0.2003 | 0.1132 | 0.1077 | 0.1373 | 0.1436 | 0.3299 | 0.2445 | 0.0003 | 0.0050 | 0.0050 | 0.0400 | 0.1026 | 0.1488 | 0.1079 | 0.1417 | 0.4487 | 38 | 59 | 80 | 102 | 128 | 157 | 190 | 236 | 297 | 0.0020 | 46.88 | 6.872 | 0.2760 | 34024.8 | 9800000 | 3360000000 | 1320000000000 | 0.5574 | 0.1310 | 0.0165 | 0.0000 | 0.1056 | 0.0050 | 0.2130 | 0.0382 | 0.1703 | 0.0893 | 0.1387 | 0.1551 | 0.1488 | 0.2086 | 0.0826 | 0.1535 | 0.0716 | 0.1259 | 0.0528 | 0.2244 | 0.0005 | 0.0000 | 0.0002 | 0.0006 | 0.0020 | 0.0016 | 0.0138 | 0.0112 | 0.0620 | 0.0424 | 0.1227 | 0.0865 | 0.0888 | 0.0730 | 0.1299 | 0.1037 | 0.5802 | 0.6811 | 0.0006 | 0.0004 | 0.0029 | 0.0049 | 0.0119 | 0.0162 | 0.0365 | 0.0503 | 0.1192 | 0.1521 | 0.1812 | 0.1923 | 0.1190 | 0.1367 | 0.1520 | 0.1559 | 0.3768 | 0.2911 | 0.0002 | 0.0009 | 0.0049 | 0.0238 | 0.0980 | 0.1462 | 0.1128 | 0.1557 | 0.4576 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 680 | 551 | | 5987 | 6093 | 134.6 | 38.08 | 176.05 | 235.22 | 92 | 104 | 113 | 122 | 129 | 138 | 148 | 161 | 182 | 0.1188 | 724 | 1.000 | 95.60 | 29.27 | 1 | 0.0403 | 241 | 0.0020 | 24.09 | 6.532 | 0.2581 | 19556.5 | 3090000 | 540000000 | 105000000000 | 0.4491 | 0.2026 | 0.0006 | 0.0000 | 0.0035 | 0.0004 | 0.0088 | 0.0006 | 0.0253 | 0.0021 | 0.0823 | 0.0225 | 0.1531 | 0.0497 | 0.1611 | 0.0584 | 0.1743 | 0.0871 | 0.3909 | 0.7792 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0031 | 0.0000 | 0.0090 | 0.0005 | 0.0374 | 0.0132 | 0.0593 | 0.0258 | 0.0654 | 0.0231 | 0.0842 | 0.0390 | 0.7408 | 0.8984 | 0.0009 | 0.0104 | 0.0128 | 0.0084 | 0.0239 | 0.0251 | 0.0632 | 0.0898 | 0.1376 | 0.1962 | 0.1709 | 0.1649 | 0.1043 | 0.1211 | 0.1564 | 0.1608 | 0.3299 | 0.2234 | 0.0023 | 0.0023 | 0.0095 | 0.0338 | 0.0834 | 0.1244 | 0.1085 | 0.1301 | 0.5059 | 10 | 11 | 13 | 16 | 34 | 115 | 229 | 352 | 553 | 0.1116 | 42.16 | 4.818 | 0.5374 | 86309.7 | 54700000 | 39600000000 | 31400000000000 | 0.5384 | 0.1532 | 0.0884 | 0.0052 | 0.2601 | 0.0551 | 0.2652 | 0.1627 | 0.1288 | 0.1890 | 0.0833 | 0.2008 | 0.0758 | 0.1444 | 0.0581 | 0.0866 | 0.0227 | 0.0735 | 0.0177 | 0.0827 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0020 | 0.0121 | 0.0068 | 0.0484 | 0.0419 | 0.0963 | 0.0971 | 0.0652 | 0.0532 | 0.0963 | 0.0789 | 0.6799 | 0.7201 | 0.0000 | 0.0006 | 0.0016 | 0.0017 | 0.0021 | 0.0058 | 0.0172 | 0.0221 | 0.0667 | 0.0813 | 0.1199 | 0.1371 | 0.0896 | 0.0936 | 0.1214 | 0.1174 | 0.5816 | 0.5404 | 0.0000 | 0.0014 | 0.0023 | 0.0136 | 0.0567 | 0.1068 | 0.0829 | 0.1036 | 0.6326 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 293 | 128 | | 4381 | 3891 | 142.2 | 45.53 | 116.54 | 68.03 | 93 | 105 | 115 | 124 | 134 | 144 | 156 | 174 | 206 | 0.1773 | 690 | 1.154 | 92.96 | 30.48 | 1 | 0.0539 | 236 | 0.0014 | 45.81 | 6.878 | 0.1869 | 22305.5 | 3870000 | 744000000 | 158000000000 | 0.4152 | 0.2335 | 0.0000 | 0.0000 | 0.0045 | 0.0003 | 0.0186 | 0.0022 | 0.0626 | 0.0091 | 0.1392 | 0.0365 | 0.1946 | 0.0890 | 0.1642 | 0.0862 | 0.1655 | 0.1307 | 0.2508 | 0.6460 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0038 | 0.0010 | 0.0190 | 0.0034 | 0.0514 | 0.0191 | 0.0936 | 0.0528 | 0.0787 | 0.0396 | 0.1148 | 0.0671 | 0.6372 | 0.8169 | 0.0021 | 0.0099 | 0.0063 | 0.0079 | 0.0264 | 0.0258 | 0.0738 | 0.0813 | 0.1276 | 0.1488 | 0.1762 | 0.1925 | 0.1171 | 0.1310 | 0.1403 | 0.1587 | 0.3302 | 0.2440 | 0.0016 | 0.0054 | 0.0136 | 0.0490 | 0.1017 | 0.1447 | 0.1181 | 0.1371 | 0.4287 | 38 | 55 | 71 | 88 | 106 | 126 | 145 | 172 | 209 | 0.0023 | 29.24 | 6.422 | 0.2512 | 18208.7 | 3510000 | 804000000 | 216000000000 | 0.4985 | 0.1471 | 0.0212 | 0.0005 | 0.0945 | 0.0070 | 0.1741 | 0.0289 | 0.1656 | 0.0690 | 0.1975 | 0.1573 | 0.1592 | 0.1669 | 0.0902 | 0.1493 | 0.0637 | 0.1728 | 0.0340 | 0.2483 | 0.0018 | 0.0000 | 0.0041 | 0.0011 | 0.0091 | 0.0040 | 0.0279 | 0.0190 | 0.0741 | 0.0623 | 0.1189 | 0.0845 | 0.1006 | 0.0758 | 0.1161 | 0.1217 | 0.5473 | 0.6316 | 0.0048 | 0.0023 | 0.0088 | 0.0137 | 0.0201 | 0.0286 | 0.0530 | 0.0766 | 0.1349 | 0.1646 | 0.1743 | 0.1737 | 0.1245 | 0.1234 | 0.1414 | 0.1349 | 0.3382 | 0.2823 | 0.0006 | 0.0069 | 0.0103 | 0.0322 | 0.0925 | 0.1516 | 0.1040 | 0.1338 | 0.4681 | ||
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 776 | 533 | | 11980 | 33861 | 383.5 | 82.50 | 120.63 | 176.56 | 283 | 310 | 334 | 355 | 376 | 398 | 421 | 451 | 496 | 0.0356 | 1205 | 1.136 | 140.66 | 55.15 | 1 | 0.0313 | 375 | 0.0009 | 37.01 | 7.234 | 0.1929 | 153867.0 | 64500000 | 28200000000 | 12800000000000 | 0.4493 | 0.2003 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0028 | 0.0000 | 0.0182 | 0.0008 | 0.0630 | 0.0134 | 0.1320 | 0.0320 | 0.1379 | 0.0333 | 0.1599 | 0.0519 | 0.4853 | 0.8686 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0010 | 0.0000 | 0.0076 | 0.0001 | 0.0277 | 0.0090 | 0.0540 | 0.0170 | 0.0581 | 0.0126 | 0.0745 | 0.0212 | 0.7764 | 0.9401 | 0.0019 | 0.0113 | 0.0047 | 0.0244 | 0.0159 | 0.0357 | 0.0637 | 0.1429 | 0.1404 | 0.1560 | 0.1807 | 0.2237 | 0.1147 | 0.0977 | 0.1470 | 0.1278 | 0.3310 | 0.1805 | 0.0004 | 0.0018 | 0.0069 | 0.0208 | 0.0738 | 0.1090 | 0.1005 | 0.1337 | 0.5532 | 7 | 8 | 10 | 13 | 28 | 71 | 135 | 223 | 358 | 0.1025 | 9.69 | 4.335 | 0.5557 | 45723.5 | 25300000 | 17600000000 | 14200000000000 | 0.3892 | 0.2409 | 0.0580 | 0.0013 | 0.2129 | 0.0223 | 0.2772 | 0.1129 | 0.1731 | 0.1468 | 0.1215 | 0.2079 | 0.0876 | 0.1983 | 0.0398 | 0.1203 | 0.0207 | 0.0982 | 0.0093 | 0.0921 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0008 | 0.0004 | 0.0071 | 0.0056 | 0.0520 | 0.0410 | 0.0868 | 0.0707 | 0.0678 | 0.0584 | 0.0917 | 0.0804 | 0.6937 | 0.7434 | 0.0005 | 0.0002 | 0.0012 | 0.0009 | 0.0018 | 0.0021 | 0.0154 | 0.0152 | 0.0663 | 0.0760 | 0.1097 | 0.1251 | 0.0819 | 0.0859 | 0.1104 | 0.1159 | 0.6128 | 0.5786 | 0.0001 | 0.0003 | 0.0013 | 0.0107 | 0.0581 | 0.1011 | 0.0739 | 0.1012 | 0.6533 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 883 | 333 | | 6557 | 23757 | 237.9 | 49.19 | 167.48 | 247.49 | 178 | 194 | 208 | 219 | 232 | 246 | 261 | 279 | 306 | 0.0424 | 1007 | 0.712 | 125.45 | 28.02 | 1 | 0.0450 | 295 | 0.0009 | 51.46 | 7.234 | 0.1754 | 59019.4 | 15300000 | 4100000000 | 1150000000000 | 0.4457 | 0.2085 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0056 | 0.0002 | 0.0195 | 0.0010 | 0.0674 | 0.0163 | 0.1393 | 0.0371 | 0.1433 | 0.0322 | 0.1613 | 0.0570 | 0.4629 | 0.8563 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0061 | 0.0002 | 0.0308 | 0.0103 | 0.0701 | 0.0231 | 0.0660 | 0.0135 | 0.0840 | 0.0266 | 0.7414 | 0.9264 | 0.0026 | 0.0174 | 0.0141 | 0.0208 | 0.0132 | 0.0590 | 0.0695 | 0.1042 | 0.1240 | 0.1979 | 0.1803 | 0.1736 | 0.1152 | 0.1285 | 0.1495 | 0.1250 | 0.3316 | 0.1736 | 0.0013 | 0.0020 | 0.0073 | 0.0295 | 0.0809 | 0.1283 | 0.1037 | 0.1332 | 0.5138 | 10 | 11 | 13 | 15 | 22 | 70 | 185 | 328 | 546 | 0.0818 | 47.97 | 5.085 | 0.5273 | 89297.6 | 63700000 | 53300000000 | 49900000000000 | 0.5956 | 0.0948 | 0.0674 | 0.0040 | 0.2566 | 0.0182 | 0.3191 | 0.1656 | 0.1332 | 0.1895 | 0.1118 | 0.2077 | 0.0683 | 0.1749 | 0.0238 | 0.1020 | 0.0132 | 0.0814 | 0.0066 | 0.0567 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0008 | 0.0079 | 0.0064 | 0.0468 | 0.0389 | 0.0815 | 0.0785 | 0.0589 | 0.0508 | 0.0832 | 0.0748 | 0.7206 | 0.7498 | 0.0003 | 0.0000 | 0.0012 | 0.0024 | 0.0026 | 0.0046 | 0.0111 | 0.0124 | 0.0508 | 0.0535 | 0.0996 | 0.1030 | 0.0647 | 0.0701 | 0.0889 | 0.0964 | 0.6808 | 0.6577 | 0.0001 | 0.0012 | 0.0017 | 0.0109 | 0.0482 | 0.0875 | 0.0665 | 0.0853 | 0.6985 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 232 | 638 | | 6254 | 5949 | 114.7 | 25.41 | 187.62 | 143.24 | 87 | 94 | 100 | 105 | 110 | 116 | 123 | 132 | 150 | 0.1308 | 778 | 0.961 | 106.23 | 31.32 | 1 | 0.0421 | 263 | 0.0034 | 14.14 | 6.046 | 0.2876 | 13792.0 | 1750000 | 233000000 | 32800000000 | 0.4648 | 0.1869 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0092 | 0.0003 | 0.0230 | 0.0024 | 0.0653 | 0.0177 | 0.1219 | 0.0491 | 0.1387 | 0.0346 | 0.1702 | 0.0694 | 0.4696 | 0.8265 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0003 | 0.0324 | 0.0105 | 0.0605 | 0.0277 | 0.0714 | 0.0137 | 0.0961 | 0.0290 | 0.7274 | 0.9189 | 0.0097 | 0.0198 | 0.0117 | 0.0074 | 0.0272 | 0.0272 | 0.0690 | 0.0743 | 0.1370 | 0.2030 | 0.1594 | 0.1807 | 0.1108 | 0.1436 | 0.1429 | 0.1337 | 0.3324 | 0.2104 | 0.0023 | 0.0109 | 0.0214 | 0.0436 | 0.1019 | 0.1320 | 0.1169 | 0.1421 | 0.4289 | 42 | 65 | 88 | 115 | 148 | 183 | 233 | 303 | 394 | 0.0021 | 69.90 | 6.913 | 0.2582 | 55713.5 | 21700000 | 10100000000 | 5300000000000 | 0.5779 | 0.0961 | 0.0346 | 0.0023 | 0.1508 | 0.0121 | 0.2315 | 0.0680 | 0.1585 | 0.1253 | 0.1537 | 0.1524 | 0.1162 | 0.1729 | 0.0836 | 0.1356 | 0.0500 | 0.1212 | 0.0211 | 0.2102 | 0.0017 | 0.0003 | 0.0017 | 0.0017 | 0.0069 | 0.0050 | 0.0247 | 0.0182 | 0.0897 | 0.0636 | 0.1357 | 0.1151 | 0.1103 | 0.0851 | 0.1454 | 0.1258 | 0.4838 | 0.5854 | 0.0016 | 0.0047 | 0.0064 | 0.0034 | 0.0112 | 0.0229 | 0.0508 | 0.0518 | 0.1086 | 0.1312 | 0.1825 | 0.1783 | 0.1215 | 0.1285 | 0.1429 | 0.1406 | 0.3745 | 0.3385 | 0.0004 | 0.0017 | 0.0120 | 0.0322 | 0.1043 | 0.1550 | 0.1245 | 0.1426 | 0.4272 |