High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 571 | 922 | 4617 | 8322 | 491.0 | 95.75 | 198.40 | 274.48 | 372 | 405 | 431 | 459 | 485 | 511 | 541 | 573 | 621 | 0.0908 | 756 | 1.217 | 121.30 | 48.70 | 1 | 0.0682 | 315 | 0.0006 | 68.44 | 7.576 | 0.1426 | 250279.0 | 132000000 | 72100000000 | 40600000000000 | 0.4178 | 0.2313 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0002 | 0.0112 | 0.0025 | 0.0586 | 0.0169 | 0.1189 | 0.0373 | 0.1287 | 0.0263 | 0.1587 | 0.0443 | 0.5217 | 0.8725 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0064 | 0.0011 | 0.0309 | 0.0133 | 0.0554 | 0.0279 | 0.0492 | 0.0168 | 0.0717 | 0.0251 | 0.7855 | 0.9157 | 0.0040 | 0.0000 | 0.0081 | 0.0000 | 0.0256 | 0.0000 | 0.0823 | 0.0000 | 0.1107 | 0.0000 | 0.1741 | 0.0000 | 0.1039 | 0.0000 | 0.1323 | 0.0000 | 0.3590 | 0.0000 | 0.0005 | 0.0023 | 0.0059 | 0.0244 | 0.0765 | 0.1199 | 0.0851 | 0.1231 | 0.5624 | 15 | 20 | 25 | 38 | 68 | 118 | 188 | 348 | 633 | 0.0340 | 31.16 | 5.359 | 0.5201 | 114691.0 | 92700000 | 87100000000 | 90400000000000 | 0.3987 | 0.2243 | 0.0214 | 0.0007 | 0.1193 | 0.0152 | 0.2370 | 0.0550 | 0.1330 | 0.0774 | 0.1361 | 0.1527 | 0.1055 | 0.2069 | 0.0826 | 0.1122 | 0.0841 | 0.1165 | 0.0810 | 0.2634 | 0.0004 | 0.0003 | 0.0029 | 0.0015 | 0.0022 | 0.0021 | 0.0122 | 0.0114 | 0.0561 | 0.0418 | 0.0820 | 0.0749 | 0.0557 | 0.0523 | 0.0805 | 0.0737 | 0.7080 | 0.7419 | 0.0005 | 0.0000 | 0.0014 | 0.0010 | 0.0056 | 0.0031 | 0.0118 | 0.0118 | 0.0592 | 0.0536 | 0.0870 | 0.1050 | 0.0602 | 0.0551 | 0.0827 | 0.0881 | 0.6916 | 0.6823 | 0.0008 | 0.0017 | 0.0033 | 0.0124 | 0.0541 | 0.0880 | 0.0570 | 0.0843 | 0.6985 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 872 | 892 | 3689 | 8762 | 488.5 | 108.21 | 84.63 | 135.98 | 344 | 390 | 427 | 458 | 489 | 518 | 545 | 576 | 623 | 0.0781 | 684 | 1.133 | 118.56 | 47.04 | 1 | 0.0848 | 313 | 0.0006 | 83.19 | 7.600 | 0.1213 | 250362.0 | 134000000 | 74800000000 | 43400000000000 | 0.4340 | 0.2055 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0153 | 0.0026 | 0.0610 | 0.0249 | 0.1194 | 0.0435 | 0.1225 | 0.0384 | 0.1500 | 0.0501 | 0.5305 | 0.8402 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0075 | 0.0017 | 0.0282 | 0.0215 | 0.0411 | 0.0345 | 0.0380 | 0.0246 | 0.0598 | 0.0328 | 0.8247 | 0.8846 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0231 | 0.0000 | 0.0738 | 0.0000 | 0.1323 | 0.0000 | 0.1877 | 0.0000 | 0.1092 | 0.0000 | 0.1154 | 0.0000 | 0.3569 | 0.0000 | 0.0000 | 0.0011 | 0.0032 | 0.0151 | 0.0572 | 0.1068 | 0.0766 | 0.1176 | 0.6224 | 14 | 16 | 19 | 24 | 34 | 51 | 71 | 100 | 208 | 0.0576 | 11.33 | 4.133 | 0.6484 | 25648.9 | 14400000 | 10400000000 | 8570000000000 | 0.5629 | 0.1030 | 0.0175 | 0.0040 | 0.0903 | 0.0070 | 0.1233 | 0.0663 | 0.1155 | 0.0713 | 0.1291 | 0.1216 | 0.1107 | 0.1266 | 0.1097 | 0.1077 | 0.1175 | 0.1171 | 0.1864 | 0.3784 | 0.0014 | 0.0017 | 0.0025 | 0.0028 | 0.0076 | 0.0083 | 0.0245 | 0.0185 | 0.0736 | 0.0578 | 0.0848 | 0.0797 | 0.0704 | 0.0606 | 0.1050 | 0.0857 | 0.6301 | 0.6850 | 0.0011 | 0.0007 | 0.0011 | 0.0027 | 0.0080 | 0.0066 | 0.0218 | 0.0199 | 0.0856 | 0.0922 | 0.1287 | 0.1293 | 0.0666 | 0.0663 | 0.1034 | 0.1015 | 0.5836 | 0.5809 | 0.0042 | 0.0056 | 0.0075 | 0.0258 | 0.0714 | 0.1104 | 0.0770 | 0.0968 | 0.6012 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 226 | 604 | 4693 | 21436 | 383.8 | 76.01 | 185.02 | 221.64 | 284 | 313 | 337 | 360 | 381 | 402 | 425 | 454 | 486 | 0.0416 | 891 | 1.052 | 130.17 | 34.01 | 1 | 0.0641 | 301 | 0.0008 | 47.52 | 7.327 | 0.1592 | 153105.0 | 63300000 | 27000000000 | 11900000000000 | 0.3995 | 0.2470 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0023 | 0.0002 | 0.0165 | 0.0017 | 0.0621 | 0.0177 | 0.1229 | 0.0293 | 0.1371 | 0.0275 | 0.1688 | 0.0446 | 0.4889 | 0.8790 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0073 | 0.0015 | 0.0275 | 0.0148 | 0.0536 | 0.0238 | 0.0573 | 0.0171 | 0.0744 | 0.0278 | 0.7785 | 0.9150 | 0.0000 | 0.0000 | 0.0120 | 0.0000 | 0.0156 | 0.0000 | 0.0648 | 0.0000 | 0.1212 | 0.0000 | 0.1633 | 0.0000 | 0.1357 | 0.0000 | 0.1465 | 0.0000 | 0.3409 | 0.0000 | 0.0000 | 0.0009 | 0.0069 | 0.0221 | 0.0711 | 0.1111 | 0.0954 | 0.1176 | 0.5748 | 15 | 18 | 24 | 44 | 80 | 141 | 230 | 343 | 529 | 0.0288 | 19.62 | 5.529 | 0.4998 | 83352.2 | 50500000 | 35500000000 | 27500000000000 | 0.4199 | 0.2507 | 0.0207 | 0.0005 | 0.0995 | 0.0062 | 0.2392 | 0.0328 | 0.2041 | 0.0859 | 0.1593 | 0.1798 | 0.1282 | 0.2251 | 0.0610 | 0.1479 | 0.0518 | 0.1262 | 0.0362 | 0.1956 | 0.0004 | 0.0000 | 0.0006 | 0.0003 | 0.0016 | 0.0010 | 0.0080 | 0.0073 | 0.0421 | 0.0351 | 0.0732 | 0.0620 | 0.0459 | 0.0433 | 0.0727 | 0.0653 | 0.7556 | 0.7856 | 0.0000 | 0.0003 | 0.0009 | 0.0012 | 0.0020 | 0.0024 | 0.0131 | 0.0137 | 0.0524 | 0.0608 | 0.0851 | 0.0996 | 0.0622 | 0.0649 | 0.0907 | 0.0941 | 0.6935 | 0.6629 | 0.0001 | 0.0005 | 0.0023 | 0.0104 | 0.0496 | 0.0769 | 0.0547 | 0.0770 | 0.7284 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 838 | 827 | 348 | 3785 | 69.6 | 9.59 | 7.19 | 2.56 | 58 | 61 | 63 | 66 | 69 | 71 | 74 | 78 | 83 | 0.1007 | 381 | 1.208 | 26.48 | 9.85 | 4 | 0.2011 | 70 | 0.0757 | 0.82 | 2.819 | 0.6940 | 4931.9 | 356260 | 26200000 | 1970000000 | 0.3634 | 0.2597 | 0.0033 | 0.0000 | 0.0100 | 0.0000 | 0.0133 | 0.0029 | 0.0332 | 0.0144 | 0.0698 | 0.0720 | 0.0997 | 0.0778 | 0.1096 | 0.0692 | 0.2359 | 0.1268 | 0.4252 | 0.6369 | 0.0030 | 0.0000 | 0.0000 | 0.0000 | 0.0090 | 0.0029 | 0.0181 | 0.0144 | 0.0633 | 0.0690 | 0.0843 | 0.0776 | 0.0663 | 0.0690 | 0.1506 | 0.1149 | 0.6054 | 0.6523 | 0.0323 | 1.0000 | 0.0000 | 0.0000 | 0.1613 | 0.0000 | 0.2258 | 0.0000 | 0.1613 | 0.0000 | 0.0968 | 0.0000 | 0.1935 | 0.0000 | 0.1290 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0062 | 0.0247 | 0.0988 | 0.1358 | 0.1420 | 0.1235 | 0.1728 | 0.2840 | 4 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 0.0188 | 7.92 | 4.396 | 0.3583 | 58.2 | 526.12 | 5258.33 | 57582.2 | 0.4841 | 0.1761 | 0.0222 | 0.0039 | 0.0672 | 0.0054 | 0.1627 | 0.0219 | 0.2267 | 0.0409 | 0.2391 | 0.0828 | 0.1725 | 0.1441 | 0.0826 | 0.2539 | 0.0246 | 0.3015 | 0.0025 | 0.1456 | 0.0046 | 0.0003 | 0.0185 | 0.0006 | 0.0490 | 0.0059 | 0.0817 | 0.0178 | 0.1214 | 0.0422 | 0.1762 | 0.0716 | 0.1689 | 0.1446 | 0.1823 | 0.2904 | 0.1974 | 0.4267 | 0.1226 | 0.1623 | 0.1493 | 0.1451 | 0.1143 | 0.1019 | 0.1184 | 0.1036 | 0.0917 | 0.0829 | 0.0937 | 0.0760 | 0.0814 | 0.0864 | 0.0937 | 0.1330 | 0.1349 | 0.1088 | 0.0153 | 0.0463 | 0.0769 | 0.1084 | 0.1441 | 0.1724 | 0.1585 | 0.1298 | 0.1483 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 382 | 919 | 6897 | 11121 | 362.8 | 74.41 | 225.10 | 252.79 | 267 | 298 | 321 | 341 | 358 | 379 | 401 | 427 | 462 | 0.0739 | 822 | 1.086 | 120.93 | 34.41 | 1 | 0.0406 | 280 | 0.0009 | 36.87 | 7.251 | 0.1983 | 137149.0 | 53900000 | 21900000000 | 9220000000000 | 0.4314 | 0.2131 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0022 | 0.0005 | 0.0135 | 0.0012 | 0.0506 | 0.0134 | 0.0981 | 0.0302 | 0.1155 | 0.0258 | 0.1361 | 0.0368 | 0.5832 | 0.8921 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0002 | 0.0004 | 0.0061 | 0.0010 | 0.0215 | 0.0104 | 0.0426 | 0.0219 | 0.0481 | 0.0148 | 0.0570 | 0.0214 | 0.8240 | 0.9300 | 0.0050 | 0.0000 | 0.0075 | 0.0000 | 0.0199 | 0.0000 | 0.0489 | 0.0000 | 0.1095 | 0.0000 | 0.1376 | 0.0000 | 0.1086 | 0.0000 | 0.1327 | 0.0000 | 0.4303 | 0.0000 | 0.0003 | 0.0024 | 0.0055 | 0.0240 | 0.0518 | 0.1046 | 0.0888 | 0.1001 | 0.6225 | 16 | 19 | 26 | 60 | 133 | 209 | 292 | 408 | 608 | 0.0252 | 45.18 | 5.945 | 0.4029 | 114568.0 | 77900000 | 62700000000 | 56900000000000 | 0.5295 | 0.1405 | 0.0233 | 0.0008 | 0.1395 | 0.0101 | 0.2197 | 0.0563 | 0.1828 | 0.1049 | 0.1612 | 0.1734 | 0.1275 | 0.1937 | 0.0762 | 0.1418 | 0.0489 | 0.1329 | 0.0209 | 0.1860 | 0.0004 | 0.0002 | 0.0004 | 0.0004 | 0.0021 | 0.0016 | 0.0092 | 0.0085 | 0.0536 | 0.0397 | 0.0929 | 0.0707 | 0.0709 | 0.0541 | 0.1009 | 0.0724 | 0.6695 | 0.7524 | 0.0003 | 0.0010 | 0.0008 | 0.0029 | 0.0058 | 0.0059 | 0.0202 | 0.0280 | 0.0810 | 0.0982 | 0.1221 | 0.1321 | 0.0928 | 0.0956 | 0.1260 | 0.1337 | 0.5510 | 0.5026 | 0.0000 | 0.0010 | 0.0036 | 0.0157 | 0.0703 | 0.1098 | 0.0834 | 0.1150 | 0.6013 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 666 | 790 | 3561 | 6069 | 315.0 | 63.10 | 119.80 | 156.57 | 227 | 261 | 284 | 299 | 314 | 331 | 348 | 367 | 395 | 0.1005 | 610 | 0.944 | 100.02 | 29.00 | 1 | 0.0702 | 250 | 0.0018 | 20.47 | 6.604 | 0.2773 | 103228.0 | 35100000 | 12300000000 | 4460000000000 | 0.4022 | 0.2404 | 0.0004 | 0.0003 | 0.0000 | 0.0003 | 0.0021 | 0.0003 | 0.0141 | 0.0006 | 0.0428 | 0.0204 | 0.0782 | 0.0351 | 0.0669 | 0.0260 | 0.0973 | 0.0348 | 0.6981 | 0.8823 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0007 | 0.0003 | 0.0034 | 0.0003 | 0.0180 | 0.0162 | 0.0312 | 0.0272 | 0.0220 | 0.0139 | 0.0339 | 0.0210 | 0.8904 | 0.9206 | 0.0055 | 0.0000 | 0.0092 | 0.0000 | 0.0295 | 0.0000 | 0.0368 | 0.0000 | 0.0976 | 0.0000 | 0.1860 | 0.0000 | 0.0994 | 0.0000 | 0.1400 | 0.0000 | 0.3959 | 0.0000 | 0.0006 | 0.0011 | 0.0034 | 0.0169 | 0.0410 | 0.0713 | 0.0691 | 0.0871 | 0.7096 | 20 | 26 | 33 | 40 | 50 | 72 | 111 | 174 | 336 | 0.0366 | 13.58 | 4.709 | 0.5959 | 38861.2 | 20100000 | 13000000000 | 9720000000000 | 0.4035 | 0.2191 | 0.0130 | 0.0025 | 0.0681 | 0.0076 | 0.1426 | 0.0245 | 0.1313 | 0.0700 | 0.1361 | 0.1308 | 0.1669 | 0.1975 | 0.1070 | 0.1156 | 0.1216 | 0.1089 | 0.1135 | 0.3426 | 0.0000 | 0.0008 | 0.0005 | 0.0004 | 0.0044 | 0.0012 | 0.0112 | 0.0082 | 0.0486 | 0.0434 | 0.0816 | 0.0643 | 0.0505 | 0.0549 | 0.0802 | 0.0680 | 0.7230 | 0.7588 | 0.0007 | 0.0008 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0160 | 0.0159 | 0.0625 | 0.0700 | 0.1006 | 0.1026 | 0.0569 | 0.0644 | 0.0944 | 0.0907 | 0.6655 | 0.6547 | 0.0000 | 0.0035 | 0.0047 | 0.0135 | 0.0541 | 0.0858 | 0.0553 | 0.0829 | 0.7002 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 792 | 805 | 4919 | 8206 | 382.1 | 68.91 | 141.31 | 188.12 | 300 | 324 | 344 | 360 | 375 | 392 | 412 | 438 | 476 | 0.0898 | 737 | 1.029 | 141.51 | 47.89 | 1 | 0.0732 | 360 | 0.0011 | 37.46 | 7.089 | 0.1984 | 150764.0 | 61400000 | 25800000000 | 11200000000000 | 0.4301 | 0.2151 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0030 | 0.0000 | 0.0107 | 0.0015 | 0.0411 | 0.0153 | 0.0748 | 0.0283 | 0.0789 | 0.0233 | 0.1114 | 0.0344 | 0.6794 | 0.8971 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0041 | 0.0008 | 0.0202 | 0.0133 | 0.0357 | 0.0198 | 0.0359 | 0.0131 | 0.0538 | 0.0182 | 0.8484 | 0.9348 | 0.0014 | 0.0000 | 0.0043 | 0.0000 | 0.0216 | 0.0000 | 0.0620 | 0.0000 | 0.1037 | 0.0000 | 0.1527 | 0.0000 | 0.1081 | 0.0000 | 0.1326 | 0.0000 | 0.4135 | 0.0000 | 0.0022 | 0.0022 | 0.0118 | 0.0263 | 0.0679 | 0.1121 | 0.0937 | 0.1222 | 0.5617 | 17 | 22 | 29 | 36 | 53 | 94 | 149 | 244 | 370 | 0.0319 | 21.94 | 5.086 | 0.5347 | 55351.4 | 34100000 | 26500000000 | 23500000000000 | 0.4596 | 0.1622 | 0.0237 | 0.0014 | 0.1379 | 0.0121 | 0.2020 | 0.0752 | 0.1323 | 0.1079 | 0.1295 | 0.1526 | 0.1337 | 0.1923 | 0.0975 | 0.1214 | 0.0641 | 0.1008 | 0.0794 | 0.2363 | 0.0000 | 0.0000 | 0.0010 | 0.0003 | 0.0007 | 0.0012 | 0.0104 | 0.0064 | 0.0542 | 0.0436 | 0.0808 | 0.0753 | 0.0636 | 0.0516 | 0.0855 | 0.0680 | 0.7037 | 0.7537 | 0.0013 | 0.0000 | 0.0000 | 0.0010 | 0.0018 | 0.0015 | 0.0075 | 0.0185 | 0.0755 | 0.0713 | 0.1132 | 0.1307 | 0.0644 | 0.0723 | 0.1012 | 0.1142 | 0.6350 | 0.5905 | 0.0004 | 0.0008 | 0.0016 | 0.0117 | 0.0600 | 0.1028 | 0.0631 | 0.0919 | 0.6678 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 692 | 185 | 19415 | 44441 | 368.7 | 56.02 | 244.04 | 276.54 | 299 | 324 | 341 | 357 | 370 | 384 | 398 | 414 | 438 | 0.0403 | 1792 | 0.714 | 124.33 | 24.70 | 1 | 0.0157 | 305 | 0.0014 | 22.18 | 6.923 | 0.2357 | 139081.0 | 53500000 | 21000000000 | 8390000000000 | 0.4311 | 0.2269 | 0.0001 | 0.0000 | 0.0008 | 0.0001 | 0.0028 | 0.0001 | 0.0066 | 0.0002 | 0.0259 | 0.0087 | 0.0530 | 0.0182 | 0.0576 | 0.0109 | 0.0865 | 0.0176 | 0.7667 | 0.9443 | 0.0001 | 0.0000 | 0.0004 | 0.0001 | 0.0011 | 0.0001 | 0.0033 | 0.0002 | 0.0141 | 0.0084 | 0.0282 | 0.0172 | 0.0273 | 0.0090 | 0.0375 | 0.0134 | 0.8880 | 0.9517 | 0.0119 | 0.0000 | 0.0209 | 0.0000 | 0.0346 | 0.0000 | 0.0930 | 0.0000 | 0.1169 | 0.0000 | 0.1574 | 0.0000 | 0.1199 | 0.0000 | 0.1306 | 0.0000 | 0.3148 | 0.0000 | 0.0012 | 0.0035 | 0.0100 | 0.0254 | 0.0509 | 0.0848 | 0.0988 | 0.1192 | 0.6061 | 17 | 22 | 30 | 54 | 118 | 220 | 341 | 473 | 647 | 0.0281 | 44.65 | 6.124 | 0.4266 | 136024.0 | 100000000 | 87800000000 | 88300000000000 | 0.4534 | 0.1804 | 0.0700 | 0.0020 | 0.2411 | 0.0134 | 0.3304 | 0.1499 | 0.1469 | 0.1951 | 0.0898 | 0.2149 | 0.0610 | 0.1886 | 0.0354 | 0.0976 | 0.0173 | 0.0724 | 0.0080 | 0.0662 | 0.0003 | 0.0002 | 0.0010 | 0.0004 | 0.0018 | 0.0013 | 0.0092 | 0.0076 | 0.0506 | 0.0416 | 0.1014 | 0.0881 | 0.0667 | 0.0543 | 0.0944 | 0.0803 | 0.6746 | 0.7262 | 0.0007 | 0.0004 | 0.0014 | 0.0017 | 0.0031 | 0.0043 | 0.0147 | 0.0194 | 0.0670 | 0.0789 | 0.1259 | 0.1392 | 0.0883 | 0.0943 | 0.1136 | 0.1275 | 0.5852 | 0.5343 | 0.0001 | 0.0007 | 0.0030 | 0.0105 | 0.0587 | 0.1131 | 0.0775 | 0.1049 | 0.6315 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 287 | 523 | 301 | 5124 | 89.9 | 7.90 | 7.40 | 2.14 | 79 | 82 | 86 | 88 | 90 | 93 | 95 | 97 | 100 | 0.0720 | 369 | 0.946 | 37.36 | 10.77 | 0 | 0.3223 | 97 | 0.1482 | 0.45 | 2.153 | 0.7860 | 8141.3 | 742840 | 68300000 | 6310000000 | 0.3690 | 0.2667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0066 | 0.0567 | 0.0532 | 0.0767 | 0.0831 | 0.0467 | 0.0432 | 0.0567 | 0.0565 | 0.7567 | 0.7575 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0066 | 0.0567 | 0.0532 | 0.0767 | 0.0831 | 0.0467 | 0.0432 | 0.0567 | 0.0565 | 0.7567 | 0.7575 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0120 | 0.0120 | 0.0542 | 0.0482 | 0.0783 | 0.1205 | 0.1084 | 0.5663 | 5 | 6 | 6 | 7 | 7 | 8 | 8 | 9 | 10 | 0.1708 | 0.51 | 1.021 | 0.4581 | 59.3 | 508.117 | 4604.6 | 43888.8 | 0.4666 | 0.2005 | 0.0058 | 0.0003 | 0.0341 | 0.0016 | 0.0942 | 0.0123 | 0.1790 | 0.0503 | 0.2344 | 0.1168 | 0.2308 | 0.1953 | 0.1477 | 0.2794 | 0.0651 | 0.2535 | 0.0090 | 0.0906 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0070 | 0.0015 | 0.0224 | 0.0088 | 0.0627 | 0.0354 | 0.1193 | 0.0626 | 0.1833 | 0.1375 | 0.3291 | 0.3390 | 0.2756 | 0.4152 | 0.0900 | 0.2589 | 0.1985 | 0.3018 | 0.2363 | 0.2417 | 0.2038 | 0.1227 | 0.1456 | 0.0577 | 0.0887 | 0.0135 | 0.0278 | 0.0025 | 0.0093 | 0.0012 | 0.0000 | 0.0000 | 0.0003 | 0.0097 | 0.0436 | 0.0951 | 0.1730 | 0.2360 | 0.2304 | 0.1642 | 0.0477 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1118 | 571 | 8114 | 11473 | 287.2 | 51.13 | 167.28 | 160.52 | 216 | 244 | 261 | 276 | 288 | 301 | 314 | 330 | 353 | 0.0825 | 946 | 0.972 | 44.55 | 15.65 | 1 | 0.0148 | 120 | 0.0020 | 14.93 | 6.529 | 0.2976 | 85117.2 | 26000000 | 8120000000 | 2600000000000 | 0.4373 | 0.2063 | 0.0005 | 0.0000 | 0.0015 | 0.0001 | 0.0027 | 0.0005 | 0.0121 | 0.0011 | 0.0320 | 0.0115 | 0.0585 | 0.0247 | 0.0605 | 0.0158 | 0.0827 | 0.0277 | 0.7495 | 0.9185 | 0.0003 | 0.0000 | 0.0003 | 0.0001 | 0.0010 | 0.0005 | 0.0049 | 0.0009 | 0.0130 | 0.0100 | 0.0228 | 0.0207 | 0.0186 | 0.0103 | 0.0277 | 0.0182 | 0.9114 | 0.9393 | 0.0075 | 0.0000 | 0.0197 | 0.0000 | 0.0254 | 0.0000 | 0.0630 | 0.0000 | 0.1006 | 0.0000 | 0.1410 | 0.0000 | 0.1194 | 0.0000 | 0.1391 | 0.0000 | 0.3844 | 0.0000 | 0.0017 | 0.0038 | 0.0094 | 0.0183 | 0.0428 | 0.0657 | 0.0729 | 0.0940 | 0.6914 | 14 | 20 | 33 | 56 | 109 | 178 | 247 | 321 | 407 | 0.0262 | 16.95 | 5.600 | 0.4608 | 53749.5 | 21300000 | 9500000000 | 4610000000000 | 0.5388 | 0.1195 | 0.0204 | 0.0036 | 0.0844 | 0.0071 | 0.2027 | 0.0554 | 0.2124 | 0.0996 | 0.1858 | 0.1765 | 0.1449 | 0.1957 | 0.0853 | 0.1425 | 0.0427 | 0.1367 | 0.0213 | 0.1828 | 0.0002 | 0.0002 | 0.0004 | 0.0000 | 0.0021 | 0.0010 | 0.0084 | 0.0088 | 0.0392 | 0.0312 | 0.0742 | 0.0636 | 0.0517 | 0.0429 | 0.0751 | 0.0700 | 0.7487 | 0.7823 | 0.0007 | 0.0000 | 0.0005 | 0.0016 | 0.0047 | 0.0066 | 0.0145 | 0.0172 | 0.0499 | 0.0620 | 0.0929 | 0.1039 | 0.0689 | 0.0823 | 0.0990 | 0.1175 | 0.6690 | 0.6089 | 0.0010 | 0.0008 | 0.0017 | 0.0109 | 0.0468 | 0.0801 | 0.0606 | 0.0887 | 0.7093 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 317 | 690 | 3464 | 11834 | 342.0 | 75.63 | 178.33 | 204.51 | 250 | 275 | 296 | 316 | 334 | 353 | 374 | 407 | 449 | 0.0724 | 857 | 0.954 | 122.41 | 43.14 | 1 | 0.0944 | 327 | 0.0010 | 39.91 | 7.112 | 0.1793 | 122696.0 | 46100000 | 18100000000 | 7380000000000 | 0.3949 | 0.2434 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0033 | 0.0000 | 0.0135 | 0.0025 | 0.0652 | 0.0246 | 0.1226 | 0.0467 | 0.1086 | 0.0418 | 0.1407 | 0.0563 | 0.5461 | 0.8278 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0061 | 0.0015 | 0.0275 | 0.0178 | 0.0582 | 0.0338 | 0.0453 | 0.0228 | 0.0735 | 0.0336 | 0.7874 | 0.8906 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0061 | 0.0000 | 0.0350 | 0.0000 | 0.1035 | 0.0000 | 0.1461 | 0.0000 | 0.0989 | 0.0000 | 0.1370 | 0.0000 | 0.4718 | 0.0000 | 0.0006 | 0.0025 | 0.0063 | 0.0151 | 0.0753 | 0.0834 | 0.0997 | 0.1173 | 0.5997 | 15 | 19 | 31 | 55 | 87 | 145 | 230 | 323 | 470 | 0.0227 | 19.50 | 5.564 | 0.4886 | 73621.5 | 41900000 | 28500000000 | 21900000000000 | 0.6117 | 0.0866 | 0.0329 | 0.0009 | 0.1078 | 0.0038 | 0.2187 | 0.0509 | 0.1920 | 0.0937 | 0.1694 | 0.1715 | 0.1283 | 0.2068 | 0.0688 | 0.1413 | 0.0431 | 0.1328 | 0.0390 | 0.1983 | 0.0002 | 0.0002 | 0.0004 | 0.0002 | 0.0017 | 0.0009 | 0.0090 | 0.0061 | 0.0363 | 0.0348 | 0.0722 | 0.0563 | 0.0539 | 0.0445 | 0.0705 | 0.0661 | 0.7557 | 0.7909 | 0.0003 | 0.0006 | 0.0018 | 0.0012 | 0.0021 | 0.0033 | 0.0127 | 0.0169 | 0.0496 | 0.0586 | 0.0939 | 0.1112 | 0.0702 | 0.0843 | 0.0915 | 0.0991 | 0.6779 | 0.6248 | 0.0000 | 0.0007 | 0.0017 | 0.0106 | 0.0439 | 0.0866 | 0.0599 | 0.0792 | 0.7175 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 77 | 299 | 362 | 804 | 84.7 | 13.26 | 9.06 | 3.12 | 65 | 72 | 78 | 84 | 87 | 90 | 93 | 96 | 100 | 0.2786 | 224 | 0.728 | 31.40 | 8.49 | 1 | 0.2459 | 89 | 0.0508 | 1.25 | 3.272 | 0.6191 | 7352.5 | 651714 | 58800000 | 5400000000 | 0.3674 | 0.2592 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0351 | 0.0028 | 0.0596 | 0.0442 | 0.1053 | 0.0912 | 0.1368 | 0.0276 | 0.1825 | 0.0608 | 0.4737 | 0.7735 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0000 | 0.0256 | 0.0028 | 0.0415 | 0.0442 | 0.0607 | 0.0912 | 0.0607 | 0.0276 | 0.0799 | 0.0608 | 0.7252 | 0.7735 | 0.0714 | 0.0000 | 0.1429 | 0.0000 | 0.1071 | 0.0000 | 0.1429 | 0.0000 | 0.2143 | 0.0000 | 0.1786 | 0.0000 | 0.0357 | 0.0000 | 0.1071 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0242 | 0.0338 | 0.0725 | 0.0725 | 0.0966 | 0.1401 | 0.5556 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 0.0140 | 20.20 | 4.617 | 0.2555 | 91.8 | 1010.84 | 11937.1 | 150060 | 0.5369 | 0.1144 | 0.0442 | 0.0017 | 0.1633 | 0.0034 | 0.2449 | 0.0458 | 0.2415 | 0.1171 | 0.1565 | 0.1460 | 0.0884 | 0.2530 | 0.0476 | 0.2054 | 0.0102 | 0.1562 | 0.0034 | 0.0713 | 0.0018 | 0.0000 | 0.0235 | 0.0000 | 0.0470 | 0.0056 | 0.1302 | 0.0405 | 0.2061 | 0.1103 | 0.2188 | 0.1494 | 0.2116 | 0.1955 | 0.1157 | 0.2598 | 0.0452 | 0.2388 | 0.1042 | 0.3150 | 0.2008 | 0.3858 | 0.2124 | 0.2283 | 0.2432 | 0.0394 | 0.1236 | 0.0315 | 0.0811 | 0.0000 | 0.0270 | 0.0000 | 0.0077 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0424 | 0.1038 | 0.2076 | 0.2182 | 0.1801 | 0.1547 | 0.0657 | 0.0233 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 563 | 523 | 7584 | 13597 | 292.9 | 83.06 | 182.75 | 174.84 | 193 | 209 | 226 | 248 | 286 | 322 | 349 | 375 | 408 | 0.0785 | 1067 | 1.101 | 127.77 | 42.45 | 1 | 0.0407 | 309 | 0.0016 | 18.42 | 6.833 | 0.3003 | 92706.4 | 31400000 | 11200000000 | 4180000000000 | 0.4037 | 0.2427 | 0.0029 | 0.0000 | 0.0068 | 0.0012 | 0.0184 | 0.0023 | 0.0417 | 0.0059 | 0.0763 | 0.0230 | 0.1000 | 0.0516 | 0.1051 | 0.0428 | 0.1263 | 0.0614 | 0.5225 | 0.8120 | 0.0010 | 0.0000 | 0.0022 | 0.0011 | 0.0026 | 0.0007 | 0.0070 | 0.0022 | 0.0191 | 0.0112 | 0.0291 | 0.0256 | 0.0275 | 0.0134 | 0.0388 | 0.0299 | 0.8726 | 0.9160 | 0.0014 | 0.0000 | 0.0023 | 0.0000 | 0.0073 | 0.0000 | 0.0200 | 0.0000 | 0.0514 | 0.0000 | 0.0906 | 0.0000 | 0.0915 | 0.0000 | 0.1138 | 0.0000 | 0.6218 | 0.0000 | 0.0000 | 0.0005 | 0.0005 | 0.0055 | 0.0191 | 0.0372 | 0.0372 | 0.0563 | 0.8437 | 21 | 37 | 61 | 91 | 127 | 171 | 226 | 307 | 431 | 0.0098 | 23.73 | 6.012 | 0.4274 | 63963.5 | 31000000 | 18200000000 | 12200000000000 | 0.4970 | 0.1734 | 0.0146 | 0.0008 | 0.0690 | 0.0059 | 0.1458 | 0.0403 | 0.1437 | 0.0687 | 0.1813 | 0.1390 | 0.1557 | 0.1647 | 0.0967 | 0.1352 | 0.0810 | 0.1280 | 0.1123 | 0.3175 | 0.0002 | 0.0000 | 0.0006 | 0.0014 | 0.0034 | 0.0032 | 0.0156 | 0.0128 | 0.0523 | 0.0433 | 0.0827 | 0.0651 | 0.0658 | 0.0553 | 0.0969 | 0.0768 | 0.6825 | 0.7421 | 0.0007 | 0.0011 | 0.0009 | 0.0049 | 0.0082 | 0.0066 | 0.0238 | 0.0255 | 0.0714 | 0.0887 | 0.1100 | 0.1319 | 0.0872 | 0.0887 | 0.1249 | 0.1379 | 0.5728 | 0.5147 | 0.0002 | 0.0029 | 0.0057 | 0.0176 | 0.0629 | 0.0975 | 0.0805 | 0.1129 | 0.6198 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 488 | 1658 | 7515 | 661.2 | 127.45 | 21.12 | 72.35 | 472 | 534 | 588 | 636 | 672 | 708 | 749 | 791 | 831 | 0.0896 | 673 | 1.056 | 79.26 | 20.40 | 1 | 0.1128 | 187 | 0.0037 | 8.63 | 5.897 | 0.3770 | 453371.0 | 321000000 | 233000000000 | 172000000000000 | 0.3992 | 0.2328 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0029 | 0.0000 | 0.0098 | 0.0018 | 0.0479 | 0.0231 | 0.0685 | 0.0358 | 0.0607 | 0.0219 | 0.0881 | 0.0328 | 0.7202 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0018 | 0.0283 | 0.0231 | 0.0358 | 0.0358 | 0.0253 | 0.0219 | 0.0365 | 0.0328 | 0.8718 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0000 | 0.0344 | 0.0000 | 0.0531 | 0.0000 | 0.0531 | 0.0000 | 0.0688 | 0.0000 | 0.1000 | 0.0000 | 0.6781 | 0.0000 | 0.0011 | 0.0011 | 0.0034 | 0.0135 | 0.0270 | 0.0529 | 0.0450 | 0.0541 | 0.8018 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 12 | 17 | 0.1063 | 2.38 | 1.499 | 0.4250 | 5680.0 | 3330000 | 2380000000 | 1890000000000 | 0.4909 | 0.1207 | 0.0780 | 0.0610 | 0.2110 | 0.0749 | 0.2844 | 0.0999 | 0.2661 | 0.1207 | 0.0826 | 0.1914 | 0.0505 | 0.1692 | 0.0092 | 0.0874 | 0.0138 | 0.0707 | 0.0046 | 0.1248 | 0.0181 | 0.0352 | 0.0233 | 0.0424 | 0.0194 | 0.0488 | 0.0440 | 0.0456 | 0.0660 | 0.0697 | 0.0699 | 0.0689 | 0.0621 | 0.0817 | 0.0776 | 0.0961 | 0.6197 | 0.5116 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0054 | 0.0000 | 0.0090 | 0.0189 | 0.0667 | 0.0682 | 0.1189 | 0.0928 | 0.0360 | 0.0625 | 0.0811 | 0.0795 | 0.6829 | 0.6761 | 0.0016 | 0.0064 | 0.0096 | 0.0305 | 0.0595 | 0.0691 | 0.0740 | 0.0804 | 0.6688 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 153 | 139 | 5758 | 11802 | 360.4 | 40.57 | 302.04 | 287.41 | 307 | 326 | 339 | 350 | 361 | 372 | 383 | 396 | 412 | 0.0835 | 986 | 0.859 | 110.32 | 27.29 | 1 | 0.0455 | 262 | 0.0019 | 22.05 | 6.508 | 0.2365 | 131562.0 | 48600000 | 18200000000 | 6860000000000 | 0.4593 | 0.1900 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0011 | 0.0000 | 0.0030 | 0.0002 | 0.0199 | 0.0116 | 0.0345 | 0.0200 | 0.0450 | 0.0106 | 0.0849 | 0.0181 | 0.8109 | 0.9396 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0002 | 0.0165 | 0.0116 | 0.0244 | 0.0200 | 0.0244 | 0.0106 | 0.0400 | 0.0181 | 0.8916 | 0.9396 | 0.0419 | 0.0000 | 0.1204 | 0.0000 | 0.1414 | 0.0000 | 0.1204 | 0.0000 | 0.0942 | 0.0000 | 0.1204 | 0.0000 | 0.1099 | 0.0000 | 0.1099 | 0.0000 | 0.1414 | 0.0000 | 0.0027 | 0.0030 | 0.0172 | 0.0320 | 0.0573 | 0.1004 | 0.1018 | 0.1375 | 0.5480 | 23 | 35 | 59 | 111 | 207 | 327 | 442 | 575 | 737 | 0.0095 | 68.30 | 6.730 | 0.3226 | 173824.0 | 123000000 | 98700000000 | 86100000000000 | 0.4300 | 0.1996 | 0.0309 | 0.0016 | 0.1561 | 0.0094 | 0.2346 | 0.0661 | 0.1920 | 0.1351 | 0.1669 | 0.2033 | 0.1068 | 0.2090 | 0.0576 | 0.1286 | 0.0434 | 0.1167 | 0.0117 | 0.1302 | 0.0002 | 0.0000 | 0.0004 | 0.0002 | 0.0011 | 0.0013 | 0.0078 | 0.0063 | 0.0446 | 0.0401 | 0.0822 | 0.0683 | 0.0522 | 0.0435 | 0.0816 | 0.0691 | 0.7299 | 0.7711 | 0.0005 | 0.0003 | 0.0007 | 0.0019 | 0.0032 | 0.0051 | 0.0178 | 0.0177 | 0.0597 | 0.0756 | 0.1097 | 0.1293 | 0.0834 | 0.0942 | 0.1134 | 0.1322 | 0.6116 | 0.5437 | 0.0000 | 0.0002 | 0.0008 | 0.0107 | 0.0530 | 0.0945 | 0.0643 | 0.1014 | 0.6751 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 199 | 260 | 10686 | 24087 | 343.1 | 42.34 | 218.62 | 243.80 | 294 | 309 | 319 | 329 | 339 | 349 | 361 | 376 | 398 | 0.0560 | 1348 | 1.108 | 80.65 | 27.02 | 2 | 0.0188 | 201 | 0.0020 | 20.94 | 6.553 | 0.2495 | 119532.0 | 42300000 | 15200000000 | 5550000000000 | 0.4430 | 0.2105 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0032 | 0.0005 | 0.0194 | 0.0089 | 0.0355 | 0.0176 | 0.0461 | 0.0113 | 0.0755 | 0.0211 | 0.8188 | 0.9407 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0015 | 0.0000 | 0.0114 | 0.0086 | 0.0212 | 0.0159 | 0.0232 | 0.0077 | 0.0352 | 0.0146 | 0.9074 | 0.9532 | 0.0199 | 0.0000 | 0.0385 | 0.0000 | 0.0442 | 0.0000 | 0.0855 | 0.0000 | 0.0954 | 0.0000 | 0.1311 | 0.0000 | 0.1197 | 0.0000 | 0.1211 | 0.0000 | 0.3447 | 0.0000 | 0.0047 | 0.0098 | 0.0155 | 0.0422 | 0.0674 | 0.0986 | 0.1131 | 0.1277 | 0.5211 | 18 | 23 | 29 | 46 | 110 | 198 | 297 | 422 | 589 | 0.0307 | 46.12 | 5.951 | 0.4302 | 107227.0 | 68300000 | 50200000000 | 40800000000000 | 0.5298 | 0.1259 | 0.0245 | 0.0018 | 0.1127 | 0.0149 | 0.2277 | 0.0610 | 0.1750 | 0.0972 | 0.1550 | 0.1809 | 0.1245 | 0.2068 | 0.0732 | 0.1277 | 0.0609 | 0.1204 | 0.0464 | 0.1894 | 0.0000 | 0.0000 | 0.0005 | 0.0002 | 0.0017 | 0.0016 | 0.0077 | 0.0073 | 0.0415 | 0.0338 | 0.0707 | 0.0588 | 0.0495 | 0.0417 | 0.0772 | 0.0625 | 0.7513 | 0.7941 | 0.0004 | 0.0004 | 0.0010 | 0.0016 | 0.0029 | 0.0041 | 0.0139 | 0.0205 | 0.0578 | 0.0653 | 0.0903 | 0.1105 | 0.0763 | 0.0890 | 0.1087 | 0.1110 | 0.6487 | 0.5975 | 0.0001 | 0.0011 | 0.0034 | 0.0105 | 0.0471 | 0.0826 | 0.0615 | 0.0887 | 0.7050 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 465 | 643 | 8720 | 12380 | 327.7 | 56.71 | 178.47 | 263.33 | 253 | 288 | 306 | 320 | 333 | 346 | 358 | 371 | 394 | 0.0826 | 1023 | 1.053 | 189.34 | 55.01 | 1 | 0.0515 | 449 | 0.0016 | 19.71 | 6.739 | 0.2552 | 110617.0 | 38300000 | 13500000000 | 4860000000000 | 0.4132 | 0.2316 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0010 | 0.0001 | 0.0059 | 0.0010 | 0.0246 | 0.0101 | 0.0541 | 0.0199 | 0.0557 | 0.0130 | 0.0950 | 0.0226 | 0.7636 | 0.9332 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0001 | 0.0030 | 0.0009 | 0.0126 | 0.0096 | 0.0228 | 0.0178 | 0.0228 | 0.0096 | 0.0370 | 0.0162 | 0.9017 | 0.9456 | 0.0114 | 0.0000 | 0.0227 | 0.0000 | 0.0272 | 0.0000 | 0.0681 | 0.0000 | 0.0988 | 0.0000 | 0.1703 | 0.0000 | 0.1067 | 0.0000 | 0.1226 | 0.0000 | 0.3723 | 0.0000 | 0.0008 | 0.0019 | 0.0071 | 0.0173 | 0.0483 | 0.0854 | 0.0861 | 0.1201 | 0.6330 | 18 | 25 | 36 | 52 | 72 | 98 | 148 | 262 | 503 | 0.0250 | 35.86 | 5.284 | 0.5431 | 101188.0 | 92200000 | 104000000000 | 133000000000000 | 0.5504 | 0.1103 | 0.0118 | 0.0028 | 0.0634 | 0.0052 | 0.1160 | 0.0282 | 0.1461 | 0.0612 | 0.1912 | 0.1266 | 0.1751 | 0.1507 | 0.1224 | 0.1351 | 0.0988 | 0.1573 | 0.0752 | 0.3329 | 0.0005 | 0.0002 | 0.0003 | 0.0011 | 0.0024 | 0.0023 | 0.0079 | 0.0094 | 0.0482 | 0.0428 | 0.0854 | 0.0656 | 0.0514 | 0.0563 | 0.0801 | 0.0808 | 0.7238 | 0.7415 | 0.0000 | 0.0000 | 0.0021 | 0.0008 | 0.0042 | 0.0035 | 0.0101 | 0.0097 | 0.0538 | 0.0635 | 0.0894 | 0.0884 | 0.0594 | 0.0666 | 0.0876 | 0.0970 | 0.6934 | 0.6706 | 0.0000 | 0.0003 | 0.0031 | 0.0089 | 0.0520 | 0.0851 | 0.0560 | 0.0875 | 0.7072 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 457 | 212 | 6322 | 18147 | 382.8 | 44.78 | 238.77 | 294.82 | 326 | 348 | 362 | 373 | 384 | 395 | 406 | 419 | 439 | 0.0600 | 1088 | 1.215 | 99.36 | 36.50 | 1 | 0.0386 | 244 | 0.0018 | 29.68 | 6.658 | 0.2214 | 148564.0 | 58400000 | 23200000000 | 9350000000000 | 0.4200 | 0.2268 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0033 | 0.0005 | 0.0198 | 0.0108 | 0.0385 | 0.0209 | 0.0480 | 0.0104 | 0.0811 | 0.0223 | 0.8084 | 0.9351 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0015 | 0.0005 | 0.0136 | 0.0108 | 0.0260 | 0.0209 | 0.0246 | 0.0104 | 0.0395 | 0.0223 | 0.8947 | 0.9351 | 0.0536 | 0.0000 | 0.0421 | 0.0000 | 0.0651 | 0.0000 | 0.1303 | 0.0000 | 0.1418 | 0.0000 | 0.2222 | 0.0000 | 0.1188 | 0.0000 | 0.1341 | 0.0000 | 0.0920 | 0.0000 | 0.0012 | 0.0049 | 0.0132 | 0.0292 | 0.0679 | 0.1075 | 0.1161 | 0.1588 | 0.5012 | 17 | 22 | 29 | 46 | 89 | 180 | 301 | 457 | 675 | 0.0295 | 57.83 | 5.943 | 0.4328 | 143927.0 | 117000000 | 112000000000 | 121000000000000 | 0.4463 | 0.1845 | 0.0546 | 0.0038 | 0.1914 | 0.0093 | 0.2906 | 0.1053 | 0.1701 | 0.1693 | 0.1184 | 0.2109 | 0.1042 | 0.1922 | 0.0475 | 0.1153 | 0.0156 | 0.0952 | 0.0078 | 0.0987 | 0.0001 | 0.0005 | 0.0011 | 0.0005 | 0.0034 | 0.0014 | 0.0108 | 0.0082 | 0.0532 | 0.0501 | 0.0872 | 0.0742 | 0.0606 | 0.0519 | 0.0872 | 0.0802 | 0.6963 | 0.7330 | 0.0005 | 0.0004 | 0.0021 | 0.0008 | 0.0042 | 0.0052 | 0.0150 | 0.0185 | 0.0656 | 0.0707 | 0.1028 | 0.1137 | 0.0807 | 0.0882 | 0.1081 | 0.1140 | 0.6208 | 0.5885 | 0.0002 | 0.0016 | 0.0046 | 0.0142 | 0.0602 | 0.0943 | 0.0678 | 0.0986 | 0.6586 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 607 | 425 | 710 | 2523 | 137.3 | 19.50 | 92.60 | 84.78 | 108 | 118 | 127 | 136 | 142 | 146 | 151 | 155 | 160 | 0.1550 | 391 | 0.898 | 77.52 | 25.50 | 1 | 0.3000 | 213 | 0.0194 | 2.48 | 4.222 | 0.5165 | 19229.6 | 2740000 | 397000000 | 58100000000 | 0.3917 | 0.2405 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0028 | 0.0547 | 0.0310 | 0.0547 | 0.0648 | 0.0813 | 0.0254 | 0.1360 | 0.0394 | 0.6617 | 0.8366 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0111 | 0.0028 | 0.0446 | 0.0310 | 0.0350 | 0.0648 | 0.0398 | 0.0254 | 0.0653 | 0.0394 | 0.8041 | 0.8366 | 0.1200 | 0.0000 | 0.2000 | 0.0000 | 0.3200 | 0.0000 | 0.0800 | 0.0000 | 0.2000 | 0.0000 | 0.0400 | 0.0000 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0290 | 0.0338 | 0.0531 | 0.0628 | 0.0773 | 0.7440 | 21 | 29 | 40 | 53 | 69 | 84 | 105 | 131 | 195 | 0.0217 | 5.49 | 4.593 | 0.5505 | 15759.1 | 4090000 | 1360000000 | 524000000000 | 0.5327 | 0.1397 | 0.0216 | 0.0021 | 0.0747 | 0.0164 | 0.0943 | 0.0472 | 0.1179 | 0.0626 | 0.1473 | 0.1067 | 0.1866 | 0.1456 | 0.1218 | 0.1292 | 0.1257 | 0.1518 | 0.1100 | 0.3385 | 0.0000 | 0.0014 | 0.0085 | 0.0041 | 0.0136 | 0.0135 | 0.0298 | 0.0230 | 0.0562 | 0.0594 | 0.1285 | 0.0939 | 0.0809 | 0.0689 | 0.1260 | 0.1060 | 0.5566 | 0.6300 | 0.0030 | 0.0099 | 0.0120 | 0.0059 | 0.0150 | 0.0198 | 0.0435 | 0.0435 | 0.0901 | 0.1087 | 0.1667 | 0.1601 | 0.0901 | 0.1186 | 0.1396 | 0.1719 | 0.4399 | 0.3617 | 0.0056 | 0.0134 | 0.0134 | 0.0335 | 0.0838 | 0.1173 | 0.1039 | 0.1363 | 0.4927 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 305 | 577 | 1224 | 107.4 | 19.71 | 5.63 | 1.94 | 82 | 89 | 96 | 101 | 108 | 113 | 118 | 125 | 133 | 0.2230 | 273 | 1.197 | 35.36 | 14.21 | 1 | 0.1664 | 96 | 0.0277 | 1.58 | 3.824 | 0.5880 | 11913.2 | 1360000 | 161000000 | 19400000000 | 0.3940 | 0.2372 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0051 | 0.0000 | 0.0304 | 0.0018 | 0.0658 | 0.0406 | 0.1392 | 0.0689 | 0.1342 | 0.0548 | 0.1519 | 0.0707 | 0.4709 | 0.7633 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0000 | 0.0000 | 0.0143 | 0.0017 | 0.0369 | 0.0399 | 0.0656 | 0.0624 | 0.0615 | 0.0295 | 0.0820 | 0.0503 | 0.7377 | 0.8163 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0968 | 0.6364 | 0.1290 | 0.1818 | 0.2796 | 0.0909 | 0.1075 | 0.0909 | 0.1398 | 0.0000 | 0.2473 | 0.0000 | 0.0034 | 0.0068 | 0.0169 | 0.0203 | 0.0811 | 0.0980 | 0.0743 | 0.0845 | 0.6149 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0263 | 7.62 | 3.939 | 0.3680 | 35.5 | 244.168 | 1810.28 | 14316.1 | 0.5714 | 0.1153 | 0.0047 | 0.0000 | 0.0712 | 0.0040 | 0.1377 | 0.0160 | 0.2389 | 0.0419 | 0.2358 | 0.1028 | 0.2294 | 0.1766 | 0.0585 | 0.2535 | 0.0190 | 0.2685 | 0.0047 | 0.1367 | 0.0000 | 0.0000 | 0.0154 | 0.0019 | 0.0475 | 0.0065 | 0.1342 | 0.0260 | 0.1853 | 0.0854 | 0.2601 | 0.1365 | 0.1936 | 0.2201 | 0.1211 | 0.2934 | 0.0428 | 0.2303 | 0.3190 | 0.5467 | 0.3667 | 0.3333 | 0.1571 | 0.1067 | 0.1238 | 0.0133 | 0.0286 | 0.0000 | 0.0048 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0280 | 0.1226 | 0.1559 | 0.1961 | 0.2259 | 0.1471 | 0.0753 | 0.0350 | 0.0140 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 559 | 1919 | 9291 | 297.6 | 53.29 | 250.19 | 260.24 | 215 | 254 | 277 | 295 | 308 | 321 | 332 | 343 | 357 | 0.0677 | 629 | 1.003 | 87.82 | 29.21 | 1 | 0.1178 | 226 | 0.0022 | 14.65 | 6.307 | 0.2647 | 91416.6 | 28800000 | 9250000000 | 3020000000000 | 0.3763 | 0.2593 | 0.0007 | 0.0005 | 0.0007 | 0.0000 | 0.0021 | 0.0005 | 0.0084 | 0.0011 | 0.0439 | 0.0183 | 0.0927 | 0.0458 | 0.0836 | 0.0188 | 0.1157 | 0.0285 | 0.6523 | 0.8864 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0012 | 0.0011 | 0.0265 | 0.0183 | 0.0468 | 0.0458 | 0.0302 | 0.0188 | 0.0406 | 0.0285 | 0.8548 | 0.8864 | 0.0105 | 0.0000 | 0.0000 | 0.0000 | 0.1000 | 0.0000 | 0.1263 | 0.0000 | 0.1842 | 0.0000 | 0.1842 | 0.0000 | 0.1421 | 0.0000 | 0.1421 | 0.0000 | 0.1105 | 0.0000 | 0.0000 | 0.0009 | 0.0036 | 0.0217 | 0.0407 | 0.0724 | 0.0733 | 0.1005 | 0.6869 | 21 | 33 | 58 | 95 | 149 | 231 | 329 | 452 | 626 | 0.0131 | 45.83 | 6.311 | 0.3810 | 130308.0 | 91600000 | 76700000000 | 72600000000000 | 0.6100 | 0.0919 | 0.0351 | 0.0025 | 0.1174 | 0.0114 | 0.2999 | 0.0602 | 0.1555 | 0.1210 | 0.1525 | 0.1916 | 0.1254 | 0.2020 | 0.0582 | 0.1432 | 0.0381 | 0.1249 | 0.0181 | 0.1432 | 0.0000 | 0.0000 | 0.0007 | 0.0006 | 0.0030 | 0.0017 | 0.0128 | 0.0101 | 0.0650 | 0.0509 | 0.0904 | 0.0798 | 0.0623 | 0.0612 | 0.1067 | 0.0878 | 0.6591 | 0.7078 | 0.0000 | 0.0004 | 0.0020 | 0.0011 | 0.0059 | 0.0061 | 0.0203 | 0.0318 | 0.0764 | 0.0842 | 0.1147 | 0.1248 | 0.0869 | 0.1083 | 0.1275 | 0.1348 | 0.5664 | 0.5084 | 0.0003 | 0.0011 | 0.0046 | 0.0154 | 0.0733 | 0.0984 | 0.0821 | 0.1146 | 0.6102 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1195 | 448 | 4077 | 9038 | 310.9 | 53.86 | 181.75 | 300.58 | 243 | 263 | 279 | 292 | 306 | 323 | 341 | 360 | 384 | 0.0823 | 744 | 0.923 | 64.47 | 17.49 | 1 | 0.0373 | 152 | 0.0015 | 24.49 | 6.739 | 0.2284 | 99584.3 | 32800000 | 11100000000 | 3850000000000 | 0.4223 | 0.2256 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0002 | 0.0166 | 0.0005 | 0.0445 | 0.0156 | 0.0831 | 0.0297 | 0.0950 | 0.0225 | 0.1292 | 0.0312 | 0.6276 | 0.9002 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0014 | 0.0002 | 0.0081 | 0.0005 | 0.0209 | 0.0152 | 0.0345 | 0.0258 | 0.0376 | 0.0142 | 0.0585 | 0.0219 | 0.8387 | 0.9222 | 0.0069 | 0.0000 | 0.0086 | 0.0000 | 0.0293 | 0.0000 | 0.0810 | 0.0000 | 0.1207 | 0.0000 | 0.1828 | 0.0000 | 0.1293 | 0.0000 | 0.1483 | 0.0000 | 0.2931 | 0.0000 | 0.0026 | 0.0021 | 0.0057 | 0.0188 | 0.0490 | 0.0834 | 0.0870 | 0.1021 | 0.6493 | 19 | 24 | 31 | 45 | 71 | 99 | 135 | 242 | 489 | 0.0344 | 32.85 | 5.199 | 0.5254 | 123371.0 | 146000000 | 217000000000 | 363000000000000 | 0.4937 | 0.1466 | 0.0515 | 0.0058 | 0.1530 | 0.0187 | 0.2641 | 0.0515 | 0.1578 | 0.1120 | 0.1401 | 0.1552 | 0.1014 | 0.1964 | 0.0354 | 0.1365 | 0.0290 | 0.1223 | 0.0676 | 0.2015 | 0.0012 | 0.0021 | 0.0063 | 0.0021 | 0.0067 | 0.0027 | 0.0185 | 0.0209 | 0.0653 | 0.0581 | 0.1034 | 0.0877 | 0.0594 | 0.0714 | 0.0975 | 0.1025 | 0.6418 | 0.6525 | 0.0005 | 0.0000 | 0.0010 | 0.0023 | 0.0031 | 0.0029 | 0.0166 | 0.0165 | 0.0786 | 0.0764 | 0.0994 | 0.1107 | 0.0708 | 0.0696 | 0.1124 | 0.1095 | 0.6176 | 0.6121 | 0.0000 | 0.0014 | 0.0023 | 0.0148 | 0.0696 | 0.1035 | 0.0650 | 0.1072 | 0.6362 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1069 | 181 | 1596 | 20629 | 124.5 | 28.67 | 72.87 | 146.49 | 98 | 102 | 107 | 111 | 116 | 122 | 130 | 143 | 162 | 0.0438 | 904 | 0.809 | 207.96 | 60.42 | 1 | 0.3440 | 549 | 0.0093 | 6.72 | 5.134 | 0.4357 | 16321.0 | 2270000 | 339000000 | 54100000000 | 0.4382 | 0.2050 | 0.0064 | 0.0000 | 0.0064 | 0.0000 | 0.0091 | 0.0000 | 0.0246 | 0.0027 | 0.0665 | 0.0317 | 0.0938 | 0.0661 | 0.1084 | 0.0465 | 0.1321 | 0.0715 | 0.5528 | 0.7815 | 0.0051 | 0.0000 | 0.0044 | 0.0000 | 0.0066 | 0.0000 | 0.0139 | 0.0025 | 0.0285 | 0.0257 | 0.0446 | 0.0426 | 0.0599 | 0.0238 | 0.0833 | 0.0401 | 0.7538 | 0.8653 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0111 | 0.0000 | 0.0406 | 0.0000 | 0.1144 | 0.0000 | 0.1476 | 0.0000 | 0.1144 | 0.0000 | 0.1255 | 0.0000 | 0.4428 | 0.0000 | 0.0016 | 0.0081 | 0.0049 | 0.0357 | 0.0535 | 0.1086 | 0.0729 | 0.1135 | 0.6013 | 7 | 9 | 11 | 12 | 13 | 15 | 19 | 61 | 281 | 0.2995 | 21.07 | 3.063 | 0.7088 | 26767.6 | 14200000 | 8950000000 | 6390000000000 | 0.3754 | 0.2426 | 0.1380 | 0.0048 | 0.3646 | 0.0530 | 0.2760 | 0.2133 | 0.1250 | 0.2337 | 0.0781 | 0.2422 | 0.0156 | 0.1627 | 0.0026 | 0.0590 | 0.0000 | 0.0217 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0005 | 0.0062 | 0.0050 | 0.0345 | 0.0311 | 0.0536 | 0.0493 | 0.0409 | 0.0369 | 0.0551 | 0.0516 | 0.8092 | 0.8256 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0018 | 0.0030 | 0.0082 | 0.0075 | 0.0356 | 0.0413 | 0.0757 | 0.0865 | 0.0522 | 0.0543 | 0.0707 | 0.0848 | 0.7559 | 0.7221 | 0.0000 | 0.0003 | 0.0008 | 0.0058 | 0.0340 | 0.0678 | 0.0421 | 0.0646 | 0.7846 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 910 | 235 | 5650 | 9484 | 613.1 | 99.25 | 15.85 | 17.71 | 472 | 537 | 575 | 601 | 623 | 643 | 663 | 690 | 733 | 0.0777 | 737 | 0.760 | 87.05 | 15.26 | 1 | 0.0388 | 219 | 0.0011 | 30.87 | 7.107 | 0.2252 | 385716.0 | 248000000 | 163000000000 | 109000000000000 | 0.3922 | 0.2485 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0043 | 0.0007 | 0.0256 | 0.0133 | 0.0488 | 0.0204 | 0.0442 | 0.0136 | 0.0551 | 0.0226 | 0.8197 | 0.9294 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0007 | 0.0151 | 0.0133 | 0.0258 | 0.0204 | 0.0208 | 0.0122 | 0.0270 | 0.0190 | 0.9099 | 0.9344 | 0.0036 | 0.2000 | 0.0145 | 0.8000 | 0.0163 | 0.0000 | 0.0435 | 0.0000 | 0.0870 | 0.0000 | 0.1431 | 0.0000 | 0.0833 | 0.0000 | 0.1105 | 0.0000 | 0.4982 | 0.0000 | 0.0019 | 0.0019 | 0.0061 | 0.0129 | 0.0399 | 0.0633 | 0.0672 | 0.0987 | 0.7081 | 5 | 7 | 8 | 9 | 11 | 13 | 15 | 20 | 32 | 0.2512 | 0.44 | 1.751 | 0.7487 | 564.9 | 50306.4 | 9130000 | 2400000000 | 0.5918 | 0.0979 | 0.0534 | 0.0357 | 0.0820 | 0.0510 | 0.0996 | 0.0522 | 0.1245 | 0.0695 | 0.1572 | 0.0948 | 0.1789 | 0.1024 | 0.1727 | 0.1371 | 0.1011 | 0.1779 | 0.0306 | 0.2793 | 0.0244 | 0.0248 | 0.0307 | 0.0322 | 0.0359 | 0.0315 | 0.0432 | 0.0424 | 0.0663 | 0.0619 | 0.0788 | 0.0696 | 0.0772 | 0.0803 | 0.1043 | 0.1080 | 0.5391 | 0.5493 | 0.0219 | 0.0129 | 0.0172 | 0.0233 | 0.0256 | 0.0259 | 0.0339 | 0.0291 | 0.0516 | 0.0505 | 0.0793 | 0.0627 | 0.0652 | 0.0524 | 0.0814 | 0.0996 | 0.6239 | 0.6436 | 0.0286 | 0.0414 | 0.0352 | 0.0447 | 0.0521 | 0.0660 | 0.0663 | 0.1015 | 0.5642 | |||
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 287 | 208 | 5091 | 12471 | 474.1 | 73.02 | 68.38 | 135.66 | 363 | 414 | 452 | 475 | 490 | 504 | 518 | 533 | 553 | 0.0763 | 952 | 1.174 | 64.62 | 19.85 | 1 | 0.0297 | 151 | 0.0020 | 19.65 | 6.571 | 0.2736 | 230087.0 | 114000000 | 57200000000 | 29100000000000 | 0.4330 | 0.2034 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0074 | 0.0012 | 0.0203 | 0.0121 | 0.0432 | 0.0234 | 0.0404 | 0.0127 | 0.0650 | 0.0183 | 0.8215 | 0.9322 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0032 | 0.0012 | 0.0131 | 0.0121 | 0.0257 | 0.0234 | 0.0181 | 0.0127 | 0.0235 | 0.0183 | 0.9163 | 0.9322 | 0.0328 | 0.0000 | 0.0615 | 0.0000 | 0.1025 | 0.0000 | 0.1311 | 0.0000 | 0.1352 | 0.0000 | 0.1352 | 0.0000 | 0.1230 | 0.0000 | 0.0820 | 0.0000 | 0.1967 | 0.0000 | 0.0000 | 0.0026 | 0.0065 | 0.0091 | 0.0308 | 0.0587 | 0.0532 | 0.0834 | 0.7557 | 6 | 8 | 9 | 11 | 15 | 21 | 36 | 71 | 216 | 0.1260 | 12.46 | 3.408 | 0.6217 | 23078.9 | 13100000 | 9690000000 | 8870000000000 | 0.4949 | 0.1599 | 0.0417 | 0.0057 | 0.1106 | 0.0278 | 0.1571 | 0.0785 | 0.1234 | 0.0849 | 0.1619 | 0.1091 | 0.1250 | 0.1320 | 0.1106 | 0.1084 | 0.1090 | 0.1434 | 0.0609 | 0.3103 | 0.0024 | 0.0014 | 0.0044 | 0.0028 | 0.0051 | 0.0068 | 0.0139 | 0.0160 | 0.0493 | 0.0376 | 0.0748 | 0.0673 | 0.0479 | 0.0450 | 0.0816 | 0.0730 | 0.7206 | 0.7501 | 0.0000 | 0.0014 | 0.0017 | 0.0009 | 0.0043 | 0.0047 | 0.0181 | 0.0161 | 0.0513 | 0.0584 | 0.0945 | 0.1011 | 0.0513 | 0.0570 | 0.0815 | 0.0783 | 0.6972 | 0.6820 | 0.0008 | 0.0012 | 0.0043 | 0.0152 | 0.0519 | 0.0831 | 0.0542 | 0.0807 | 0.7087 |