High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 226 | 604 | | 4693 | 21436 | 383.8 | 76.01 | 185.02 | 221.64 | 284 | 313 | 337 | 360 | 381 | 402 | 425 | 454 | 486 | 0.0416 | 891 | 1.052 | 130.17 | 34.01 | 1 | 0.0641 | 301 | 0.0008 | 47.52 | 7.327 | 0.1592 | 153105.0 | 63300000 | 27000000000 | 11900000000000 | 0.3995 | 0.2470 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0023 | 0.0002 | 0.0165 | 0.0017 | 0.0621 | 0.0177 | 0.1229 | 0.0293 | 0.1371 | 0.0275 | 0.1688 | 0.0446 | 0.4889 | 0.8790 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0073 | 0.0015 | 0.0275 | 0.0148 | 0.0536 | 0.0238 | 0.0573 | 0.0171 | 0.0744 | 0.0278 | 0.7785 | 0.9150 | 0.0000 | 0.0000 | 0.0120 | 0.0000 | 0.0156 | 0.0000 | 0.0648 | 0.0000 | 0.1212 | 0.0000 | 0.1633 | 0.0000 | 0.1357 | 0.0000 | 0.1465 | 0.0000 | 0.3409 | 0.0000 | 0.0000 | 0.0009 | 0.0069 | 0.0221 | 0.0711 | 0.1111 | 0.0954 | 0.1176 | 0.5748 | 15 | 18 | 24 | 44 | 80 | 141 | 230 | 343 | 529 | 0.0288 | 19.62 | 5.529 | 0.4998 | 83352.2 | 50500000 | 35500000000 | 27500000000000 | 0.4199 | 0.2507 | 0.0207 | 0.0005 | 0.0995 | 0.0062 | 0.2392 | 0.0328 | 0.2041 | 0.0859 | 0.1593 | 0.1798 | 0.1282 | 0.2251 | 0.0610 | 0.1479 | 0.0518 | 0.1262 | 0.0362 | 0.1956 | 0.0004 | 0.0000 | 0.0006 | 0.0003 | 0.0016 | 0.0010 | 0.0080 | 0.0073 | 0.0421 | 0.0351 | 0.0732 | 0.0620 | 0.0459 | 0.0433 | 0.0727 | 0.0653 | 0.7556 | 0.7856 | 0.0000 | 0.0003 | 0.0009 | 0.0012 | 0.0020 | 0.0024 | 0.0131 | 0.0137 | 0.0524 | 0.0608 | 0.0851 | 0.0996 | 0.0622 | 0.0649 | 0.0907 | 0.0941 | 0.6935 | 0.6629 | 0.0001 | 0.0005 | 0.0023 | 0.0104 | 0.0496 | 0.0769 | 0.0547 | 0.0770 | 0.7284 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 270 | 229 | | 650 | 7025 | 1251.1 | 283.87 | 11.58 | 3.56 | 859 | 957 | 1050 | 1150 | 1249 | 1356 | 1450 | 1553 | 1640 | 0.0757 | 532 | 1.003 | 35.47 | 12.37 | 1 | 0.1554 | 101 | 0.0018 | 76.01 | 6.355 | 0.1286 | 1650000.0 | 2260000000 | 3210000000000 | 4.71E+15 | 0.3546 | 0.2714 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0861 | 0.0357 | 0.1632 | 0.0683 | 0.0950 | 0.0233 | 0.1424 | 0.0714 | 0.5104 | 0.8012 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0405 | 0.0356 | 0.0729 | 0.0681 | 0.0304 | 0.0232 | 0.0547 | 0.0464 | 0.7996 | 0.8266 | 0.0000 | 1.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0127 | 0.0000 | 0.0828 | 0.0000 | 0.1083 | 0.0000 | 0.0573 | 0.0000 | 0.1083 | 0.0000 | 0.6306 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0093 | 0.0556 | 0.0710 | 0.0525 | 0.0556 | 0.7562 | 7 | 9 | 10 | 11 | 11 | 12 | 13 | 14 | 16 | 0.0081 | 16.06 | 5.190 | 0.2777 | 146.9 | 2017.49 | 29808.4 | 471003 | 0.4942 | 0.1529 | 0.0108 | 0.0007 | 0.0396 | 0.0047 | 0.0930 | 0.0132 | 0.1508 | 0.0346 | 0.2124 | 0.0636 | 0.2362 | 0.1307 | 0.1635 | 0.2187 | 0.0792 | 0.3144 | 0.0144 | 0.2194 | 0.0046 | 0.0002 | 0.0197 | 0.0029 | 0.0427 | 0.0088 | 0.0534 | 0.0212 | 0.0813 | 0.0412 | 0.1242 | 0.0726 | 0.1697 | 0.1078 | 0.2247 | 0.2453 | 0.2797 | 0.5001 | 0.1226 | 0.2147 | 0.1534 | 0.1587 | 0.1534 | 0.1635 | 0.1480 | 0.1346 | 0.1180 | 0.1010 | 0.0987 | 0.0737 | 0.0887 | 0.0561 | 0.0717 | 0.0657 | 0.0455 | 0.0321 | 0.0277 | 0.0639 | 0.0858 | 0.1141 | 0.1354 | 0.1515 | 0.1521 | 0.1263 | 0.1433 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1069 | 181 | | 1596 | 20629 | 124.5 | 28.67 | 72.87 | 146.49 | 98 | 102 | 107 | 111 | 116 | 122 | 130 | 143 | 162 | 0.0438 | 904 | 0.809 | 207.96 | 60.42 | 1 | 0.3440 | 549 | 0.0093 | 6.72 | 5.134 | 0.4357 | 16321.0 | 2270000 | 339000000 | 54100000000 | 0.4382 | 0.2050 | 0.0064 | 0.0000 | 0.0064 | 0.0000 | 0.0091 | 0.0000 | 0.0246 | 0.0027 | 0.0665 | 0.0317 | 0.0938 | 0.0661 | 0.1084 | 0.0465 | 0.1321 | 0.0715 | 0.5528 | 0.7815 | 0.0051 | 0.0000 | 0.0044 | 0.0000 | 0.0066 | 0.0000 | 0.0139 | 0.0025 | 0.0285 | 0.0257 | 0.0446 | 0.0426 | 0.0599 | 0.0238 | 0.0833 | 0.0401 | 0.7538 | 0.8653 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0111 | 0.0000 | 0.0406 | 0.0000 | 0.1144 | 0.0000 | 0.1476 | 0.0000 | 0.1144 | 0.0000 | 0.1255 | 0.0000 | 0.4428 | 0.0000 | 0.0016 | 0.0081 | 0.0049 | 0.0357 | 0.0535 | 0.1086 | 0.0729 | 0.1135 | 0.6013 | 7 | 9 | 11 | 12 | 13 | 15 | 19 | 61 | 281 | 0.2995 | 21.07 | 3.063 | 0.7088 | 26767.6 | 14200000 | 8950000000 | 6390000000000 | 0.3754 | 0.2426 | 0.1380 | 0.0048 | 0.3646 | 0.0530 | 0.2760 | 0.2133 | 0.1250 | 0.2337 | 0.0781 | 0.2422 | 0.0156 | 0.1627 | 0.0026 | 0.0590 | 0.0000 | 0.0217 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0005 | 0.0062 | 0.0050 | 0.0345 | 0.0311 | 0.0536 | 0.0493 | 0.0409 | 0.0369 | 0.0551 | 0.0516 | 0.8092 | 0.8256 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0018 | 0.0030 | 0.0082 | 0.0075 | 0.0356 | 0.0413 | 0.0757 | 0.0865 | 0.0522 | 0.0543 | 0.0707 | 0.0848 | 0.7559 | 0.7221 | 0.0000 | 0.0003 | 0.0008 | 0.0058 | 0.0340 | 0.0678 | 0.0421 | 0.0646 | 0.7846 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 343 | 266 | | 9188 | 10970 | 380.5 | 50.11 | 368.80 | 331.03 | 317 | 338 | 353 | 366 | 379 | 392 | 407 | 423 | 446 | 0.0837 | 918 | 1.098 | 128.97 | 29.02 | 1 | 0.0293 | 269 | 0.0014 | 32.93 | 6.904 | 0.2140 | 147263.0 | 58000000 | 23200000000 | 9410000000000 | 0.4808 | 0.1754 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0047 | 0.0002 | 0.0250 | 0.0095 | 0.0514 | 0.0210 | 0.0529 | 0.0104 | 0.0987 | 0.0165 | 0.7665 | 0.9424 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0012 | 0.0001 | 0.0138 | 0.0095 | 0.0278 | 0.0207 | 0.0261 | 0.0093 | 0.0415 | 0.0143 | 0.8895 | 0.9462 | 0.0218 | 0.0000 | 0.0328 | 0.0000 | 0.0593 | 0.0000 | 0.0874 | 0.0000 | 0.1732 | 0.0000 | 0.1841 | 0.0000 | 0.1435 | 0.0000 | 0.1388 | 0.0000 | 0.1591 | 0.0000 | 0.0011 | 0.0040 | 0.0097 | 0.0303 | 0.0725 | 0.1067 | 0.1129 | 0.1309 | 0.5320 | 26 | 44 | 103 | 182 | 274 | 391 | 529 | 679 | 850 | 0.0115 | 87.23 | 6.899 | 0.3039 | 245585.0 | 203000000 | 190000000000 | 195000000000000 | 0.5450 | 0.1332 | 0.0240 | 0.0019 | 0.1159 | 0.0052 | 0.2589 | 0.0480 | 0.1785 | 0.1152 | 0.1414 | 0.1989 | 0.1291 | 0.2063 | 0.0765 | 0.1279 | 0.0433 | 0.1290 | 0.0325 | 0.1677 | 0.0004 | 0.0003 | 0.0015 | 0.0005 | 0.0044 | 0.0031 | 0.0158 | 0.0085 | 0.0472 | 0.0440 | 0.0846 | 0.0769 | 0.0584 | 0.0516 | 0.0824 | 0.0766 | 0.7053 | 0.7384 | 0.0003 | 0.0009 | 0.0025 | 0.0032 | 0.0058 | 0.0059 | 0.0156 | 0.0215 | 0.0666 | 0.0792 | 0.1115 | 0.1340 | 0.0860 | 0.1022 | 0.1267 | 0.1240 | 0.5849 | 0.5290 | 0.0000 | 0.0026 | 0.0050 | 0.0109 | 0.0579 | 0.0934 | 0.0690 | 0.0986 | 0.6626 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1215 | 337 | | 5299 | 15208 | 314.6 | 49.18 | 289.78 | 445.68 | 258 | 273 | 285 | 295 | 306 | 318 | 334 | 356 | 383 | 0.0592 | 900 | 0.916 | 116.83 | 42.76 | 1 | 0.0670 | 355 | 0.0017 | 23.16 | 6.655 | 0.2317 | 101403.0 | 33500000 | 11400000000 | 3950000000000 | 0.3986 | 0.2511 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0023 | 0.0000 | 0.0093 | 0.0002 | 0.0305 | 0.0140 | 0.0753 | 0.0305 | 0.0827 | 0.0190 | 0.1286 | 0.0295 | 0.6705 | 0.9068 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0033 | 0.0000 | 0.0158 | 0.0117 | 0.0404 | 0.0247 | 0.0404 | 0.0102 | 0.0640 | 0.0160 | 0.8348 | 0.9373 | 0.0063 | 0.0000 | 0.0158 | 0.0000 | 0.0412 | 0.0000 | 0.0824 | 0.0000 | 0.1173 | 0.0000 | 0.1347 | 0.0000 | 0.1094 | 0.0000 | 0.1410 | 0.0000 | 0.3518 | 0.0000 | 0.0022 | 0.0083 | 0.0188 | 0.0419 | 0.0777 | 0.1104 | 0.0877 | 0.1144 | 0.5386 | 14 | 17 | 20 | 24 | 37 | 96 | 310 | 568 | 955 | 0.0512 | 92.27 | 5.412 | 0.4889 | 282587.0 | 374000000 | 589000000000 | 1.04E+15 | 0.4260 | 0.2078 | 0.0678 | 0.0021 | 0.2554 | 0.0310 | 0.2713 | 0.1590 | 0.1515 | 0.1654 | 0.1154 | 0.1977 | 0.0736 | 0.1668 | 0.0375 | 0.0880 | 0.0202 | 0.0992 | 0.0072 | 0.0908 | 0.0000 | 0.0000 | 0.0002 | 0.0006 | 0.0006 | 0.0002 | 0.0058 | 0.0039 | 0.0392 | 0.0362 | 0.0676 | 0.0614 | 0.0464 | 0.0369 | 0.0642 | 0.0614 | 0.7760 | 0.7994 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0016 | 0.0038 | 0.0107 | 0.0111 | 0.0513 | 0.0494 | 0.0801 | 0.0970 | 0.0632 | 0.0688 | 0.0880 | 0.0932 | 0.7051 | 0.6762 | 0.0000 | 0.0000 | 0.0009 | 0.0068 | 0.0458 | 0.0717 | 0.0503 | 0.0824 | 0.7421 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 946 | 911 | | 326 | 5218 | 83.2 | 12.55 | 6.61 | 2.23 | 66 | 72 | 76 | 80 | 84 | 87 | 90 | 94 | 100 | 0.0922 | 481 | 0.870 | 40.79 | 10.82 | 5 | 0.2883 | 94 | 0.0484 | 1.29 | 3.265 | 0.6193 | 7072.0 | 613833 | 54300000 | 4880000000 | 0.3970 | 0.2342 | 0.0039 | 0.0000 | 0.0039 | 0.0000 | 0.0078 | 0.0000 | 0.0310 | 0.0153 | 0.0698 | 0.0429 | 0.1512 | 0.0798 | 0.1163 | 0.0583 | 0.1860 | 0.0828 | 0.4302 | 0.7209 | 0.0034 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0206 | 0.0153 | 0.0309 | 0.0429 | 0.0997 | 0.0798 | 0.0550 | 0.0583 | 0.0928 | 0.0828 | 0.6907 | 0.7209 | 0.0303 | 0.0000 | 0.0909 | 0.0000 | 0.0909 | 0.0000 | 0.1818 | 0.0000 | 0.1818 | 0.0000 | 0.2121 | 0.0000 | 0.1212 | 0.0000 | 0.0606 | 0.0000 | 0.0303 | 0.0000 | 0.0055 | 0.0000 | 0.0110 | 0.0440 | 0.0714 | 0.1484 | 0.1154 | 0.2033 | 0.4011 | 4 | 5 | 6 | 6 | 6 | 7 | 7 | 9 | 9 | 0.0270 | 9.36 | 4.124 | 0.3431 | 48.6 | 391.422 | 3419.3 | 32319.8 | 0.5324 | 0.1461 | 0.0043 | 0.0011 | 0.0274 | 0.0040 | 0.0990 | 0.0214 | 0.1877 | 0.0631 | 0.2444 | 0.1213 | 0.2369 | 0.2069 | 0.1372 | 0.2618 | 0.0545 | 0.2256 | 0.0086 | 0.0948 | 0.0005 | 0.0002 | 0.0028 | 0.0019 | 0.0165 | 0.0091 | 0.0505 | 0.0369 | 0.1170 | 0.0831 | 0.1931 | 0.1470 | 0.2540 | 0.2323 | 0.2307 | 0.2820 | 0.1350 | 0.2075 | 0.1429 | 0.4528 | 0.2778 | 0.2397 | 0.2169 | 0.0896 | 0.1614 | 0.0557 | 0.0750 | 0.0436 | 0.0547 | 0.0533 | 0.0335 | 0.0412 | 0.0247 | 0.0194 | 0.0132 | 0.0048 | 0.0201 | 0.0768 | 0.1695 | 0.2209 | 0.1962 | 0.1531 | 0.0866 | 0.0497 | 0.0271 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 713 | 522 | | 16894 | 27359 | 277.6 | 52.05 | 216.35 | 215.57 | 208 | 237 | 256 | 269 | 281 | 294 | 306 | 320 | 341 | 0.0538 | 1471 | 1.091 | 103.16 | 31.06 | 2 | 0.0146 | 247 | 0.0019 | 13.94 | 6.613 | 0.2949 | 79797.3 | 23600000 | 7150000000 | 2220000000000 | 0.4393 | 0.2062 | 0.0005 | 0.0001 | 0.0011 | 0.0000 | 0.0033 | 0.0002 | 0.0092 | 0.0012 | 0.0381 | 0.0103 | 0.0669 | 0.0200 | 0.0670 | 0.0172 | 0.0957 | 0.0278 | 0.7182 | 0.9233 | 0.0001 | 0.0001 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0036 | 0.0009 | 0.0175 | 0.0093 | 0.0294 | 0.0173 | 0.0273 | 0.0120 | 0.0360 | 0.0204 | 0.8849 | 0.9400 | 0.0059 | 0.0000 | 0.0174 | 0.0000 | 0.0329 | 0.0000 | 0.0567 | 0.0000 | 0.1025 | 0.0000 | 0.1459 | 0.0000 | 0.1189 | 0.0000 | 0.1432 | 0.0000 | 0.3765 | 0.0000 | 0.0017 | 0.0028 | 0.0050 | 0.0176 | 0.0419 | 0.0771 | 0.0726 | 0.0997 | 0.6818 | 21 | 32 | 52 | 93 | 142 | 205 | 283 | 380 | 530 | 0.0112 | 32.03 | 6.315 | 0.3897 | 93278.7 | 53900000 | 36900000000 | 28400000000000 | 0.5194 | 0.1468 | 0.0368 | 0.0022 | 0.1715 | 0.0112 | 0.2748 | 0.0782 | 0.1614 | 0.1448 | 0.1334 | 0.1933 | 0.0945 | 0.1853 | 0.0577 | 0.1275 | 0.0408 | 0.1189 | 0.0291 | 0.1384 | 0.0004 | 0.0005 | 0.0011 | 0.0010 | 0.0036 | 0.0028 | 0.0148 | 0.0107 | 0.0581 | 0.0512 | 0.1064 | 0.0873 | 0.0753 | 0.0672 | 0.1096 | 0.0986 | 0.6307 | 0.6805 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0066 | 0.0087 | 0.0278 | 0.0330 | 0.0781 | 0.0932 | 0.1289 | 0.1454 | 0.1017 | 0.1011 | 0.1260 | 0.1267 | 0.5291 | 0.4877 | 0.0007 | 0.0016 | 0.0048 | 0.0183 | 0.0725 | 0.1147 | 0.0880 | 0.1182 | 0.5812 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 77 | 299 | | 362 | 804 | 84.7 | 13.26 | 9.06 | 3.12 | 65 | 72 | 78 | 84 | 87 | 90 | 93 | 96 | 100 | 0.2786 | 224 | 0.728 | 31.40 | 8.49 | 1 | 0.2459 | 89 | 0.0508 | 1.25 | 3.272 | 0.6191 | 7352.5 | 651714 | 58800000 | 5400000000 | 0.3674 | 0.2592 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0351 | 0.0028 | 0.0596 | 0.0442 | 0.1053 | 0.0912 | 0.1368 | 0.0276 | 0.1825 | 0.0608 | 0.4737 | 0.7735 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0000 | 0.0256 | 0.0028 | 0.0415 | 0.0442 | 0.0607 | 0.0912 | 0.0607 | 0.0276 | 0.0799 | 0.0608 | 0.7252 | 0.7735 | 0.0714 | 0.0000 | 0.1429 | 0.0000 | 0.1071 | 0.0000 | 0.1429 | 0.0000 | 0.2143 | 0.0000 | 0.1786 | 0.0000 | 0.0357 | 0.0000 | 0.1071 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0242 | 0.0338 | 0.0725 | 0.0725 | 0.0966 | 0.1401 | 0.5556 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 0.0140 | 20.20 | 4.617 | 0.2555 | 91.8 | 1010.84 | 11937.1 | 150060 | 0.5369 | 0.1144 | 0.0442 | 0.0017 | 0.1633 | 0.0034 | 0.2449 | 0.0458 | 0.2415 | 0.1171 | 0.1565 | 0.1460 | 0.0884 | 0.2530 | 0.0476 | 0.2054 | 0.0102 | 0.1562 | 0.0034 | 0.0713 | 0.0018 | 0.0000 | 0.0235 | 0.0000 | 0.0470 | 0.0056 | 0.1302 | 0.0405 | 0.2061 | 0.1103 | 0.2188 | 0.1494 | 0.2116 | 0.1955 | 0.1157 | 0.2598 | 0.0452 | 0.2388 | 0.1042 | 0.3150 | 0.2008 | 0.3858 | 0.2124 | 0.2283 | 0.2432 | 0.0394 | 0.1236 | 0.0315 | 0.0811 | 0.0000 | 0.0270 | 0.0000 | 0.0077 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0424 | 0.1038 | 0.2076 | 0.2182 | 0.1801 | 0.1547 | 0.0657 | 0.0233 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 244 | 404 | | 494 | 2485 | 92.6 | 12.71 | 8.21 | 2.59 | 77 | 82 | 85 | 87 | 91 | 94 | 99 | 105 | 111 | 0.1469 | 365 | 1.264 | 23.35 | 8.54 | 2 | 0.1215 | 60 | 0.0560 | 0.95 | 3.137 | 0.6794 | 8731.3 | 838707 | 82000000 | 8150000000 | 0.3994 | 0.2357 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0071 | 0.0000 | 0.0165 | 0.0020 | 0.0615 | 0.0405 | 0.1229 | 0.0749 | 0.0827 | 0.0283 | 0.1348 | 0.0445 | 0.5745 | 0.8097 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0020 | 0.0404 | 0.0405 | 0.0702 | 0.0749 | 0.0319 | 0.0283 | 0.0574 | 0.0445 | 0.7915 | 0.8097 | 0.0000 | 0.0000 | 0.0851 | 0.0000 | 0.1277 | 0.0000 | 0.1915 | 0.0000 | 0.2128 | 0.0000 | 0.1702 | 0.0000 | 0.1064 | 0.0000 | 0.1064 | 0.0000 | 0.0000 | 0.0000 | 0.0089 | 0.0133 | 0.0089 | 0.0356 | 0.0667 | 0.0889 | 0.0933 | 0.1200 | 0.5644 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0177 | 10.75 | 4.510 | 0.3406 | 74.1 | 727.275 | 7718.61 | 88127.3 | 0.5118 | 0.1497 | 0.0233 | 0.0000 | 0.0933 | 0.0043 | 0.1707 | 0.0071 | 0.2341 | 0.0331 | 0.2211 | 0.0576 | 0.1763 | 0.0997 | 0.0606 | 0.1790 | 0.0187 | 0.3226 | 0.0019 | 0.2966 | 0.0017 | 0.0000 | 0.0207 | 0.0013 | 0.0407 | 0.0030 | 0.0878 | 0.0127 | 0.1228 | 0.0348 | 0.1641 | 0.0556 | 0.1922 | 0.0824 | 0.1876 | 0.2238 | 0.1824 | 0.5864 | 0.1028 | 0.2563 | 0.1416 | 0.2059 | 0.1490 | 0.1681 | 0.1714 | 0.1261 | 0.1222 | 0.1176 | 0.1386 | 0.0588 | 0.1073 | 0.0504 | 0.0566 | 0.0168 | 0.0104 | 0.0000 | 0.0115 | 0.0413 | 0.0678 | 0.1287 | 0.1430 | 0.1714 | 0.1850 | 0.1558 | 0.0955 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1060 | 312 | | 8531 | 15239 | 406.2 | 51.13 | 226.15 | 245.25 | 342 | 364 | 380 | 392 | 404 | 416 | 431 | 449 | 474 | 0.0668 | 1018 | 0.868 | 57.87 | 17.89 | 1 | 0.0178 | 152 | 0.0013 | 38.37 | 6.954 | 0.1978 | 167626.0 | 70200000 | 29900000000 | 12900000000000 | 0.4561 | 0.1965 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0042 | 0.0000 | 0.0191 | 0.0097 | 0.0469 | 0.0162 | 0.0566 | 0.0088 | 0.0892 | 0.0171 | 0.7825 | 0.9482 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0011 | 0.0000 | 0.0126 | 0.0097 | 0.0255 | 0.0162 | 0.0268 | 0.0088 | 0.0439 | 0.0152 | 0.8900 | 0.9501 | 0.0146 | 1.0000 | 0.0419 | 0.0000 | 0.0419 | 0.0000 | 0.1129 | 0.0000 | 0.1548 | 0.0000 | 0.1876 | 0.0000 | 0.1220 | 0.0000 | 0.1275 | 0.0000 | 0.1967 | 0.0000 | 0.0026 | 0.0043 | 0.0115 | 0.0412 | 0.0740 | 0.1178 | 0.1135 | 0.1283 | 0.5068 | 15 | 19 | 31 | 68 | 137 | 220 | 311 | 421 | 569 | 0.0214 | 62.72 | 6.209 | 0.3748 | 111286.0 | 74000000 | 60400000000 | 58100000000000 | 0.5099 | 0.1391 | 0.0526 | 0.0022 | 0.1940 | 0.0114 | 0.2544 | 0.1134 | 0.1674 | 0.1438 | 0.1298 | 0.1878 | 0.1032 | 0.1837 | 0.0545 | 0.1188 | 0.0292 | 0.1096 | 0.0149 | 0.1292 | 0.0000 | 0.0001 | 0.0001 | 0.0004 | 0.0007 | 0.0003 | 0.0079 | 0.0047 | 0.0500 | 0.0399 | 0.0844 | 0.0694 | 0.0697 | 0.0522 | 0.1028 | 0.0844 | 0.6841 | 0.7486 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0027 | 0.0049 | 0.0148 | 0.0281 | 0.0769 | 0.0926 | 0.1317 | 0.1530 | 0.1039 | 0.1070 | 0.1377 | 0.1459 | 0.5322 | 0.4672 | 0.0000 | 0.0000 | 0.0020 | 0.0090 | 0.0602 | 0.1073 | 0.0860 | 0.1254 | 0.6102 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 772 | | 630 | 2293 | 62.2 | 11.79 | 6.82 | 2.35 | 48 | 51 | 54 | 57 | 61 | 65 | 69 | 73 | 77 | 0.1522 | 349 | 0.662 | 34.06 | 7.21 | 2 | 0.1444 | 91 | 0.0668 | 0.76 | 2.979 | 0.7113 | 4008.3 | 267309 | 18400000 | 1310000000 | 0.4337 | 0.1967 | 0.0000 | 0.0000 | 0.0115 | 0.0000 | 0.0253 | 0.0016 | 0.0484 | 0.0081 | 0.1106 | 0.0520 | 0.1521 | 0.0846 | 0.1728 | 0.0618 | 0.2166 | 0.1317 | 0.2627 | 0.6602 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0075 | 0.0016 | 0.0226 | 0.0048 | 0.0658 | 0.0476 | 0.0921 | 0.0778 | 0.0714 | 0.0429 | 0.1372 | 0.0984 | 0.5996 | 0.7270 | 0.0102 | 0.1333 | 0.0408 | 0.0000 | 0.0612 | 0.1333 | 0.1633 | 0.4000 | 0.1837 | 0.0000 | 0.2245 | 0.2667 | 0.1224 | 0.0000 | 0.1020 | 0.0000 | 0.0918 | 0.0667 | 0.0000 | 0.0000 | 0.0065 | 0.0647 | 0.0971 | 0.1100 | 0.1197 | 0.1553 | 0.4466 | 4 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 10 | 0.0239 | 6.69 | 4.216 | 0.3943 | 52.0 | 441.077 | 4128.92 | 42300.9 | 0.5603 | 0.1272 | 0.0098 | 0.0035 | 0.0446 | 0.0081 | 0.1223 | 0.0190 | 0.1982 | 0.0432 | 0.2580 | 0.0876 | 0.1839 | 0.1643 | 0.1205 | 0.2190 | 0.0509 | 0.2824 | 0.0116 | 0.1729 | 0.0044 | 0.0000 | 0.0196 | 0.0010 | 0.0418 | 0.0068 | 0.0982 | 0.0209 | 0.1483 | 0.0507 | 0.1781 | 0.0989 | 0.1749 | 0.1495 | 0.1477 | 0.2567 | 0.1869 | 0.4155 | 0.1638 | 0.1855 | 0.1048 | 0.0943 | 0.1114 | 0.1006 | 0.1048 | 0.1132 | 0.1201 | 0.1226 | 0.1004 | 0.1164 | 0.1048 | 0.1069 | 0.0873 | 0.0943 | 0.1026 | 0.0660 | 0.0254 | 0.0806 | 0.1569 | 0.1490 | 0.1350 | 0.1060 | 0.1060 | 0.0947 | 0.1464 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 559 | | 1919 | 9291 | 297.6 | 53.29 | 250.19 | 260.24 | 215 | 254 | 277 | 295 | 308 | 321 | 332 | 343 | 357 | 0.0677 | 629 | 1.003 | 87.82 | 29.21 | 1 | 0.1178 | 226 | 0.0022 | 14.65 | 6.307 | 0.2647 | 91416.6 | 28800000 | 9250000000 | 3020000000000 | 0.3763 | 0.2593 | 0.0007 | 0.0005 | 0.0007 | 0.0000 | 0.0021 | 0.0005 | 0.0084 | 0.0011 | 0.0439 | 0.0183 | 0.0927 | 0.0458 | 0.0836 | 0.0188 | 0.1157 | 0.0285 | 0.6523 | 0.8864 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0012 | 0.0011 | 0.0265 | 0.0183 | 0.0468 | 0.0458 | 0.0302 | 0.0188 | 0.0406 | 0.0285 | 0.8548 | 0.8864 | 0.0105 | 0.0000 | 0.0000 | 0.0000 | 0.1000 | 0.0000 | 0.1263 | 0.0000 | 0.1842 | 0.0000 | 0.1842 | 0.0000 | 0.1421 | 0.0000 | 0.1421 | 0.0000 | 0.1105 | 0.0000 | 0.0000 | 0.0009 | 0.0036 | 0.0217 | 0.0407 | 0.0724 | 0.0733 | 0.1005 | 0.6869 | 21 | 33 | 58 | 95 | 149 | 231 | 329 | 452 | 626 | 0.0131 | 45.83 | 6.311 | 0.3810 | 130308.0 | 91600000 | 76700000000 | 72600000000000 | 0.6100 | 0.0919 | 0.0351 | 0.0025 | 0.1174 | 0.0114 | 0.2999 | 0.0602 | 0.1555 | 0.1210 | 0.1525 | 0.1916 | 0.1254 | 0.2020 | 0.0582 | 0.1432 | 0.0381 | 0.1249 | 0.0181 | 0.1432 | 0.0000 | 0.0000 | 0.0007 | 0.0006 | 0.0030 | 0.0017 | 0.0128 | 0.0101 | 0.0650 | 0.0509 | 0.0904 | 0.0798 | 0.0623 | 0.0612 | 0.1067 | 0.0878 | 0.6591 | 0.7078 | 0.0000 | 0.0004 | 0.0020 | 0.0011 | 0.0059 | 0.0061 | 0.0203 | 0.0318 | 0.0764 | 0.0842 | 0.1147 | 0.1248 | 0.0869 | 0.1083 | 0.1275 | 0.1348 | 0.5664 | 0.5084 | 0.0003 | 0.0011 | 0.0046 | 0.0154 | 0.0733 | 0.0984 | 0.0821 | 0.1146 | 0.6102 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 292 | 776 | | 6777 | 12524 | 325.6 | 51.91 | 172.85 | 222.30 | 258 | 277 | 296 | 311 | 323 | 337 | 352 | 369 | 393 | 0.0787 | 986 | 1.019 | 135.34 | 41.01 | 1 | 0.0484 | 328 | 0.0017 | 16.93 | 6.629 | 0.2646 | 108700.0 | 37200000 | 13000000000 | 4670000000000 | 0.3905 | 0.2545 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0001 | 0.0131 | 0.0003 | 0.0300 | 0.0124 | 0.0571 | 0.0234 | 0.0742 | 0.0142 | 0.0991 | 0.0285 | 0.7210 | 0.9211 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0000 | 0.0071 | 0.0001 | 0.0167 | 0.0114 | 0.0295 | 0.0193 | 0.0326 | 0.0106 | 0.0443 | 0.0171 | 0.8660 | 0.9414 | 0.0057 | 0.0000 | 0.0114 | 0.0000 | 0.0341 | 0.0000 | 0.0994 | 0.0000 | 0.0994 | 0.0000 | 0.1605 | 0.0000 | 0.1179 | 0.0000 | 0.1264 | 0.0000 | 0.3452 | 0.0000 | 0.0015 | 0.0034 | 0.0073 | 0.0208 | 0.0531 | 0.0784 | 0.0815 | 0.1227 | 0.6313 | 14 | 16 | 19 | 25 | 51 | 113 | 215 | 343 | 515 | 0.0450 | 24.78 | 5.251 | 0.4914 | 79286.9 | 49200000 | 36500000000 | 31300000000000 | 0.4891 | 0.1521 | 0.0682 | 0.0006 | 0.2302 | 0.0144 | 0.3264 | 0.1428 | 0.1949 | 0.1888 | 0.1084 | 0.2199 | 0.0560 | 0.1929 | 0.0097 | 0.1180 | 0.0049 | 0.0760 | 0.0012 | 0.0466 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0015 | 0.0099 | 0.0101 | 0.0578 | 0.0482 | 0.0893 | 0.0778 | 0.0562 | 0.0523 | 0.0885 | 0.0782 | 0.6971 | 0.7317 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0023 | 0.0032 | 0.0138 | 0.0193 | 0.0706 | 0.0776 | 0.1115 | 0.1144 | 0.0701 | 0.0761 | 0.0996 | 0.1129 | 0.6310 | 0.5957 | 0.0000 | 0.0000 | 0.0012 | 0.0129 | 0.0628 | 0.1014 | 0.0584 | 0.0960 | 0.6673 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 465 | 643 | | 8720 | 12380 | 327.7 | 56.71 | 178.47 | 263.33 | 253 | 288 | 306 | 320 | 333 | 346 | 358 | 371 | 394 | 0.0826 | 1023 | 1.053 | 189.34 | 55.01 | 1 | 0.0515 | 449 | 0.0016 | 19.71 | 6.739 | 0.2552 | 110617.0 | 38300000 | 13500000000 | 4860000000000 | 0.4132 | 0.2316 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0010 | 0.0001 | 0.0059 | 0.0010 | 0.0246 | 0.0101 | 0.0541 | 0.0199 | 0.0557 | 0.0130 | 0.0950 | 0.0226 | 0.7636 | 0.9332 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0001 | 0.0030 | 0.0009 | 0.0126 | 0.0096 | 0.0228 | 0.0178 | 0.0228 | 0.0096 | 0.0370 | 0.0162 | 0.9017 | 0.9456 | 0.0114 | 0.0000 | 0.0227 | 0.0000 | 0.0272 | 0.0000 | 0.0681 | 0.0000 | 0.0988 | 0.0000 | 0.1703 | 0.0000 | 0.1067 | 0.0000 | 0.1226 | 0.0000 | 0.3723 | 0.0000 | 0.0008 | 0.0019 | 0.0071 | 0.0173 | 0.0483 | 0.0854 | 0.0861 | 0.1201 | 0.6330 | 18 | 25 | 36 | 52 | 72 | 98 | 148 | 262 | 503 | 0.0250 | 35.86 | 5.284 | 0.5431 | 101188.0 | 92200000 | 104000000000 | 133000000000000 | 0.5504 | 0.1103 | 0.0118 | 0.0028 | 0.0634 | 0.0052 | 0.1160 | 0.0282 | 0.1461 | 0.0612 | 0.1912 | 0.1266 | 0.1751 | 0.1507 | 0.1224 | 0.1351 | 0.0988 | 0.1573 | 0.0752 | 0.3329 | 0.0005 | 0.0002 | 0.0003 | 0.0011 | 0.0024 | 0.0023 | 0.0079 | 0.0094 | 0.0482 | 0.0428 | 0.0854 | 0.0656 | 0.0514 | 0.0563 | 0.0801 | 0.0808 | 0.7238 | 0.7415 | 0.0000 | 0.0000 | 0.0021 | 0.0008 | 0.0042 | 0.0035 | 0.0101 | 0.0097 | 0.0538 | 0.0635 | 0.0894 | 0.0884 | 0.0594 | 0.0666 | 0.0876 | 0.0970 | 0.6934 | 0.6706 | 0.0000 | 0.0003 | 0.0031 | 0.0089 | 0.0520 | 0.0851 | 0.0560 | 0.0875 | 0.7072 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1036 | 656 | | 6909 | 17984 | 410.6 | 89.98 | 149.03 | 156.51 | 291 | 332 | 361 | 387 | 409 | 432 | 457 | 486 | 536 | 0.0622 | 1118 | 0.898 | 69.57 | 17.20 | 1 | 0.0248 | 171 | 0.0008 | 36.78 | 7.401 | 0.1966 | 176674.0 | 79200000 | 36900000000 | 17700000000000 | 0.4312 | 0.2120 | 0.0007 | 0.0000 | 0.0016 | 0.0002 | 0.0034 | 0.0005 | 0.0108 | 0.0020 | 0.0391 | 0.0147 | 0.0913 | 0.0355 | 0.0855 | 0.0290 | 0.1133 | 0.0461 | 0.6543 | 0.8720 | 0.0004 | 0.0000 | 0.0004 | 0.0001 | 0.0025 | 0.0000 | 0.0034 | 0.0009 | 0.0166 | 0.0112 | 0.0378 | 0.0207 | 0.0314 | 0.0124 | 0.0448 | 0.0203 | 0.8629 | 0.9343 | 0.0032 | 0.0000 | 0.0080 | 0.0000 | 0.0135 | 0.0000 | 0.0358 | 0.0000 | 0.0923 | 0.0000 | 0.1146 | 0.0000 | 0.0819 | 0.0000 | 0.1233 | 0.0000 | 0.5274 | 0.0000 | 0.0006 | 0.0024 | 0.0059 | 0.0221 | 0.0489 | 0.0734 | 0.0681 | 0.0943 | 0.6844 | 11 | 14 | 25 | 52 | 91 | 138 | 202 | 281 | 382 | 0.0546 | 17.50 | 5.311 | 0.5113 | 46702.5 | 19100000 | 9060000000 | 4790000000000 | 0.5773 | 0.1082 | 0.0176 | 0.0024 | 0.0828 | 0.0099 | 0.1823 | 0.0387 | 0.1855 | 0.0739 | 0.1780 | 0.1442 | 0.1507 | 0.1991 | 0.0866 | 0.1416 | 0.0663 | 0.1505 | 0.0502 | 0.2396 | 0.0004 | 0.0002 | 0.0013 | 0.0009 | 0.0018 | 0.0020 | 0.0098 | 0.0055 | 0.0367 | 0.0299 | 0.0651 | 0.0490 | 0.0517 | 0.0398 | 0.0765 | 0.0650 | 0.7568 | 0.8077 | 0.0005 | 0.0006 | 0.0005 | 0.0012 | 0.0035 | 0.0038 | 0.0112 | 0.0175 | 0.0539 | 0.0691 | 0.1009 | 0.1110 | 0.0752 | 0.0900 | 0.1122 | 0.1267 | 0.6422 | 0.5802 | 0.0003 | 0.0004 | 0.0029 | 0.0108 | 0.0469 | 0.0779 | 0.0647 | 0.0975 | 0.6985 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 600 | | 4616 | 7928 | 344.2 | 66.06 | 265.90 | 254.61 | 259 | 286 | 308 | 325 | 341 | 359 | 377 | 401 | 435 | 0.1043 | 827 | 1.180 | 138.18 | 54.34 | 1 | 0.0782 | 361 | 0.0012 | 25.73 | 6.964 | 0.2269 | 122856.0 | 45400000 | 17300000000 | 6770000000000 | 0.4140 | 0.2347 | 0.0009 | 0.0000 | 0.0025 | 0.0002 | 0.0041 | 0.0002 | 0.0173 | 0.0013 | 0.0447 | 0.0183 | 0.0676 | 0.0359 | 0.0711 | 0.0219 | 0.1101 | 0.0415 | 0.6818 | 0.8807 | 0.0005 | 0.0000 | 0.0015 | 0.0000 | 0.0020 | 0.0000 | 0.0077 | 0.0007 | 0.0197 | 0.0159 | 0.0277 | 0.0303 | 0.0289 | 0.0135 | 0.0451 | 0.0266 | 0.8668 | 0.9131 | 0.0028 | 0.0000 | 0.0041 | 0.0000 | 0.0180 | 0.0000 | 0.0511 | 0.0000 | 0.0898 | 0.0000 | 0.1367 | 0.0000 | 0.1450 | 0.0000 | 0.1257 | 0.0000 | 0.4268 | 0.0000 | 0.0013 | 0.0031 | 0.0071 | 0.0205 | 0.0361 | 0.0672 | 0.0828 | 0.1033 | 0.6785 | 30 | 47 | 84 | 143 | 199 | 254 | 331 | 426 | 605 | 0.0066 | 47.91 | 6.596 | 0.3097 | 135523.0 | 96800000 | 84600000000 | 83800000000000 | 0.5314 | 0.1336 | 0.0148 | 0.0008 | 0.0818 | 0.0076 | 0.2167 | 0.0239 | 0.1528 | 0.0725 | 0.1730 | 0.1457 | 0.1302 | 0.1803 | 0.1005 | 0.1489 | 0.0733 | 0.1636 | 0.0569 | 0.2568 | 0.0000 | 0.0000 | 0.0011 | 0.0007 | 0.0061 | 0.0013 | 0.0143 | 0.0088 | 0.0586 | 0.0424 | 0.1040 | 0.0805 | 0.0828 | 0.0621 | 0.1157 | 0.0988 | 0.6175 | 0.7053 | 0.0008 | 0.0010 | 0.0016 | 0.0075 | 0.0076 | 0.0139 | 0.0298 | 0.0378 | 0.0953 | 0.0925 | 0.1460 | 0.1492 | 0.0973 | 0.1089 | 0.1375 | 0.1318 | 0.4841 | 0.4575 | 0.0003 | 0.0016 | 0.0046 | 0.0178 | 0.0753 | 0.1358 | 0.0976 | 0.1289 | 0.5381 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 792 | 805 | | 4919 | 8206 | 382.1 | 68.91 | 141.31 | 188.12 | 300 | 324 | 344 | 360 | 375 | 392 | 412 | 438 | 476 | 0.0898 | 737 | 1.029 | 141.51 | 47.89 | 1 | 0.0732 | 360 | 0.0011 | 37.46 | 7.089 | 0.1984 | 150764.0 | 61400000 | 25800000000 | 11200000000000 | 0.4301 | 0.2151 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0030 | 0.0000 | 0.0107 | 0.0015 | 0.0411 | 0.0153 | 0.0748 | 0.0283 | 0.0789 | 0.0233 | 0.1114 | 0.0344 | 0.6794 | 0.8971 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0041 | 0.0008 | 0.0202 | 0.0133 | 0.0357 | 0.0198 | 0.0359 | 0.0131 | 0.0538 | 0.0182 | 0.8484 | 0.9348 | 0.0014 | 0.0000 | 0.0043 | 0.0000 | 0.0216 | 0.0000 | 0.0620 | 0.0000 | 0.1037 | 0.0000 | 0.1527 | 0.0000 | 0.1081 | 0.0000 | 0.1326 | 0.0000 | 0.4135 | 0.0000 | 0.0022 | 0.0022 | 0.0118 | 0.0263 | 0.0679 | 0.1121 | 0.0937 | 0.1222 | 0.5617 | 17 | 22 | 29 | 36 | 53 | 94 | 149 | 244 | 370 | 0.0319 | 21.94 | 5.086 | 0.5347 | 55351.4 | 34100000 | 26500000000 | 23500000000000 | 0.4596 | 0.1622 | 0.0237 | 0.0014 | 0.1379 | 0.0121 | 0.2020 | 0.0752 | 0.1323 | 0.1079 | 0.1295 | 0.1526 | 0.1337 | 0.1923 | 0.0975 | 0.1214 | 0.0641 | 0.1008 | 0.0794 | 0.2363 | 0.0000 | 0.0000 | 0.0010 | 0.0003 | 0.0007 | 0.0012 | 0.0104 | 0.0064 | 0.0542 | 0.0436 | 0.0808 | 0.0753 | 0.0636 | 0.0516 | 0.0855 | 0.0680 | 0.7037 | 0.7537 | 0.0013 | 0.0000 | 0.0000 | 0.0010 | 0.0018 | 0.0015 | 0.0075 | 0.0185 | 0.0755 | 0.0713 | 0.1132 | 0.1307 | 0.0644 | 0.0723 | 0.1012 | 0.1142 | 0.6350 | 0.5905 | 0.0004 | 0.0008 | 0.0016 | 0.0117 | 0.0600 | 0.1028 | 0.0631 | 0.0919 | 0.6678 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1211 | 757 | | 6987 | 17413 | 330.1 | 42.49 | 131.75 | 174.14 | 277 | 295 | 309 | 320 | 331 | 341 | 352 | 366 | 384 | 0.0637 | 1110 | 0.875 | 72.84 | 16.16 | 1 | 0.0238 | 166 | 0.0022 | 16.55 | 6.447 | 0.2611 | 110777.0 | 37800000 | 13100000000 | 4580000000000 | 0.4400 | 0.2087 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0062 | 0.0000 | 0.0213 | 0.0109 | 0.0321 | 0.0178 | 0.0485 | 0.0100 | 0.0745 | 0.0186 | 0.8160 | 0.9427 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0000 | 0.0128 | 0.0109 | 0.0169 | 0.0178 | 0.0198 | 0.0095 | 0.0305 | 0.0166 | 0.9167 | 0.9453 | 0.0122 | 0.0000 | 0.0389 | 1.0000 | 0.0681 | 0.0000 | 0.1387 | 0.0000 | 0.1363 | 0.0000 | 0.1533 | 0.0000 | 0.1314 | 0.0000 | 0.1265 | 0.0000 | 0.1946 | 0.0000 | 0.0017 | 0.0047 | 0.0111 | 0.0255 | 0.0505 | 0.0813 | 0.0921 | 0.1160 | 0.6171 | 11 | 14 | 16 | 20 | 45 | 85 | 148 | 242 | 391 | 0.0761 | 18.56 | 4.883 | 0.5466 | 47679.7 | 24000000 | 14300000000 | 9510000000000 | 0.5710 | 0.1004 | 0.0354 | 0.0022 | 0.1286 | 0.0170 | 0.1973 | 0.0815 | 0.1517 | 0.1130 | 0.1402 | 0.1735 | 0.1156 | 0.1590 | 0.0860 | 0.1101 | 0.0744 | 0.1093 | 0.0708 | 0.2342 | 0.0002 | 0.0003 | 0.0005 | 0.0013 | 0.0017 | 0.0015 | 0.0103 | 0.0083 | 0.0444 | 0.0392 | 0.0713 | 0.0616 | 0.0547 | 0.0447 | 0.0799 | 0.0686 | 0.7370 | 0.7746 | 0.0002 | 0.0007 | 0.0022 | 0.0016 | 0.0044 | 0.0034 | 0.0156 | 0.0158 | 0.0577 | 0.0657 | 0.0944 | 0.1062 | 0.0716 | 0.0725 | 0.0954 | 0.1069 | 0.6586 | 0.6274 | 0.0004 | 0.0009 | 0.0034 | 0.0130 | 0.0497 | 0.0852 | 0.0639 | 0.0887 | 0.6949 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1195 | 448 | | 4077 | 9038 | 310.9 | 53.86 | 181.75 | 300.58 | 243 | 263 | 279 | 292 | 306 | 323 | 341 | 360 | 384 | 0.0823 | 744 | 0.923 | 64.47 | 17.49 | 1 | 0.0373 | 152 | 0.0015 | 24.49 | 6.739 | 0.2284 | 99584.3 | 32800000 | 11100000000 | 3850000000000 | 0.4223 | 0.2256 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0002 | 0.0166 | 0.0005 | 0.0445 | 0.0156 | 0.0831 | 0.0297 | 0.0950 | 0.0225 | 0.1292 | 0.0312 | 0.6276 | 0.9002 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0014 | 0.0002 | 0.0081 | 0.0005 | 0.0209 | 0.0152 | 0.0345 | 0.0258 | 0.0376 | 0.0142 | 0.0585 | 0.0219 | 0.8387 | 0.9222 | 0.0069 | 0.0000 | 0.0086 | 0.0000 | 0.0293 | 0.0000 | 0.0810 | 0.0000 | 0.1207 | 0.0000 | 0.1828 | 0.0000 | 0.1293 | 0.0000 | 0.1483 | 0.0000 | 0.2931 | 0.0000 | 0.0026 | 0.0021 | 0.0057 | 0.0188 | 0.0490 | 0.0834 | 0.0870 | 0.1021 | 0.6493 | 19 | 24 | 31 | 45 | 71 | 99 | 135 | 242 | 489 | 0.0344 | 32.85 | 5.199 | 0.5254 | 123371.0 | 146000000 | 217000000000 | 363000000000000 | 0.4937 | 0.1466 | 0.0515 | 0.0058 | 0.1530 | 0.0187 | 0.2641 | 0.0515 | 0.1578 | 0.1120 | 0.1401 | 0.1552 | 0.1014 | 0.1964 | 0.0354 | 0.1365 | 0.0290 | 0.1223 | 0.0676 | 0.2015 | 0.0012 | 0.0021 | 0.0063 | 0.0021 | 0.0067 | 0.0027 | 0.0185 | 0.0209 | 0.0653 | 0.0581 | 0.1034 | 0.0877 | 0.0594 | 0.0714 | 0.0975 | 0.1025 | 0.6418 | 0.6525 | 0.0005 | 0.0000 | 0.0010 | 0.0023 | 0.0031 | 0.0029 | 0.0166 | 0.0165 | 0.0786 | 0.0764 | 0.0994 | 0.1107 | 0.0708 | 0.0696 | 0.1124 | 0.1095 | 0.6176 | 0.6121 | 0.0000 | 0.0014 | 0.0023 | 0.0148 | 0.0696 | 0.1035 | 0.0650 | 0.1072 | 0.6362 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 838 | 827 | | 348 | 3785 | 69.6 | 9.59 | 7.19 | 2.56 | 58 | 61 | 63 | 66 | 69 | 71 | 74 | 78 | 83 | 0.1007 | 381 | 1.208 | 26.48 | 9.85 | 4 | 0.2011 | 70 | 0.0757 | 0.82 | 2.819 | 0.6940 | 4931.9 | 356260 | 26200000 | 1970000000 | 0.3634 | 0.2597 | 0.0033 | 0.0000 | 0.0100 | 0.0000 | 0.0133 | 0.0029 | 0.0332 | 0.0144 | 0.0698 | 0.0720 | 0.0997 | 0.0778 | 0.1096 | 0.0692 | 0.2359 | 0.1268 | 0.4252 | 0.6369 | 0.0030 | 0.0000 | 0.0000 | 0.0000 | 0.0090 | 0.0029 | 0.0181 | 0.0144 | 0.0633 | 0.0690 | 0.0843 | 0.0776 | 0.0663 | 0.0690 | 0.1506 | 0.1149 | 0.6054 | 0.6523 | 0.0323 | 1.0000 | 0.0000 | 0.0000 | 0.1613 | 0.0000 | 0.2258 | 0.0000 | 0.1613 | 0.0000 | 0.0968 | 0.0000 | 0.1935 | 0.0000 | 0.1290 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0062 | 0.0247 | 0.0988 | 0.1358 | 0.1420 | 0.1235 | 0.1728 | 0.2840 | 4 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 0.0188 | 7.92 | 4.396 | 0.3583 | 58.2 | 526.12 | 5258.33 | 57582.2 | 0.4841 | 0.1761 | 0.0222 | 0.0039 | 0.0672 | 0.0054 | 0.1627 | 0.0219 | 0.2267 | 0.0409 | 0.2391 | 0.0828 | 0.1725 | 0.1441 | 0.0826 | 0.2539 | 0.0246 | 0.3015 | 0.0025 | 0.1456 | 0.0046 | 0.0003 | 0.0185 | 0.0006 | 0.0490 | 0.0059 | 0.0817 | 0.0178 | 0.1214 | 0.0422 | 0.1762 | 0.0716 | 0.1689 | 0.1446 | 0.1823 | 0.2904 | 0.1974 | 0.4267 | 0.1226 | 0.1623 | 0.1493 | 0.1451 | 0.1143 | 0.1019 | 0.1184 | 0.1036 | 0.0917 | 0.0829 | 0.0937 | 0.0760 | 0.0814 | 0.0864 | 0.0937 | 0.1330 | 0.1349 | 0.1088 | 0.0153 | 0.0463 | 0.0769 | 0.1084 | 0.1441 | 0.1724 | 0.1585 | 0.1298 | 0.1483 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 153 | 139 | | 5758 | 11802 | 360.4 | 40.57 | 302.04 | 287.41 | 307 | 326 | 339 | 350 | 361 | 372 | 383 | 396 | 412 | 0.0835 | 986 | 0.859 | 110.32 | 27.29 | 1 | 0.0455 | 262 | 0.0019 | 22.05 | 6.508 | 0.2365 | 131562.0 | 48600000 | 18200000000 | 6860000000000 | 0.4593 | 0.1900 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0011 | 0.0000 | 0.0030 | 0.0002 | 0.0199 | 0.0116 | 0.0345 | 0.0200 | 0.0450 | 0.0106 | 0.0849 | 0.0181 | 0.8109 | 0.9396 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0002 | 0.0165 | 0.0116 | 0.0244 | 0.0200 | 0.0244 | 0.0106 | 0.0400 | 0.0181 | 0.8916 | 0.9396 | 0.0419 | 0.0000 | 0.1204 | 0.0000 | 0.1414 | 0.0000 | 0.1204 | 0.0000 | 0.0942 | 0.0000 | 0.1204 | 0.0000 | 0.1099 | 0.0000 | 0.1099 | 0.0000 | 0.1414 | 0.0000 | 0.0027 | 0.0030 | 0.0172 | 0.0320 | 0.0573 | 0.1004 | 0.1018 | 0.1375 | 0.5480 | 23 | 35 | 59 | 111 | 207 | 327 | 442 | 575 | 737 | 0.0095 | 68.30 | 6.730 | 0.3226 | 173824.0 | 123000000 | 98700000000 | 86100000000000 | 0.4300 | 0.1996 | 0.0309 | 0.0016 | 0.1561 | 0.0094 | 0.2346 | 0.0661 | 0.1920 | 0.1351 | 0.1669 | 0.2033 | 0.1068 | 0.2090 | 0.0576 | 0.1286 | 0.0434 | 0.1167 | 0.0117 | 0.1302 | 0.0002 | 0.0000 | 0.0004 | 0.0002 | 0.0011 | 0.0013 | 0.0078 | 0.0063 | 0.0446 | 0.0401 | 0.0822 | 0.0683 | 0.0522 | 0.0435 | 0.0816 | 0.0691 | 0.7299 | 0.7711 | 0.0005 | 0.0003 | 0.0007 | 0.0019 | 0.0032 | 0.0051 | 0.0178 | 0.0177 | 0.0597 | 0.0756 | 0.1097 | 0.1293 | 0.0834 | 0.0942 | 0.1134 | 0.1322 | 0.6116 | 0.5437 | 0.0000 | 0.0002 | 0.0008 | 0.0107 | 0.0530 | 0.0945 | 0.0643 | 0.1014 | 0.6751 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 159 | 548 | | 379 | 3429 | 61.1 | 11.87 | 9.11 | 3.08 | 46 | 49 | 53 | 56 | 61 | 64 | 69 | 74 | 78 | 0.1105 | 379 | 1.104 | 39.12 | 14.21 | 3 | 0.2797 | 106 | 0.0614 | 0.78 | 2.978 | 0.7032 | 3871.4 | 253941 | 17200000 | 1190000000 | 0.4114 | 0.2187 | 0.0000 | 0.0000 | 0.0338 | 0.0000 | 0.0211 | 0.0027 | 0.0717 | 0.0133 | 0.1392 | 0.0398 | 0.1477 | 0.0928 | 0.1477 | 0.0398 | 0.1181 | 0.0955 | 0.3207 | 0.7162 | 0.0000 | 0.0000 | 0.0223 | 0.0000 | 0.0096 | 0.0026 | 0.0287 | 0.0132 | 0.0510 | 0.0396 | 0.0701 | 0.0923 | 0.0605 | 0.0343 | 0.0764 | 0.0686 | 0.6815 | 0.7493 | 0.0000 | 0.0000 | 0.0000 | 1.0000 | 0.0519 | 0.0000 | 0.0649 | 0.0000 | 0.2208 | 0.0000 | 0.1818 | 0.0000 | 0.2078 | 0.0000 | 0.1688 | 0.0000 | 0.1039 | 0.0000 | 0.0000 | 0.0209 | 0.0105 | 0.0419 | 0.0995 | 0.0942 | 0.1047 | 0.1152 | 0.5131 | 5 | 7 | 7 | 8 | 9 | 10 | 10 | 11 | 13 | 0.0137 | 13.19 | 4.745 | 0.3048 | 92.4 | 1038.16 | 12866.9 | 175722 | 0.4767 | 0.1774 | 0.0306 | 0.0011 | 0.0977 | 0.0053 | 0.1939 | 0.0174 | 0.2558 | 0.0474 | 0.2165 | 0.0913 | 0.1348 | 0.1588 | 0.0547 | 0.2421 | 0.0160 | 0.2736 | 0.0000 | 0.1629 | 0.0040 | 0.0000 | 0.0215 | 0.0007 | 0.0553 | 0.0059 | 0.0975 | 0.0180 | 0.1615 | 0.0475 | 0.1708 | 0.0992 | 0.1550 | 0.1490 | 0.1519 | 0.2449 | 0.1826 | 0.4348 | 0.1258 | 0.1928 | 0.1479 | 0.1639 | 0.1336 | 0.1470 | 0.1291 | 0.1012 | 0.1049 | 0.1036 | 0.0894 | 0.1108 | 0.0993 | 0.0916 | 0.1038 | 0.0675 | 0.0662 | 0.0217 | 0.0221 | 0.0550 | 0.1024 | 0.1185 | 0.1422 | 0.1212 | 0.1315 | 0.1245 | 0.1827 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 457 | 212 | | 6322 | 18147 | 382.8 | 44.78 | 238.77 | 294.82 | 326 | 348 | 362 | 373 | 384 | 395 | 406 | 419 | 439 | 0.0600 | 1088 | 1.215 | 99.36 | 36.50 | 1 | 0.0386 | 244 | 0.0018 | 29.68 | 6.658 | 0.2214 | 148564.0 | 58400000 | 23200000000 | 9350000000000 | 0.4200 | 0.2268 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0033 | 0.0005 | 0.0198 | 0.0108 | 0.0385 | 0.0209 | 0.0480 | 0.0104 | 0.0811 | 0.0223 | 0.8084 | 0.9351 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0015 | 0.0005 | 0.0136 | 0.0108 | 0.0260 | 0.0209 | 0.0246 | 0.0104 | 0.0395 | 0.0223 | 0.8947 | 0.9351 | 0.0536 | 0.0000 | 0.0421 | 0.0000 | 0.0651 | 0.0000 | 0.1303 | 0.0000 | 0.1418 | 0.0000 | 0.2222 | 0.0000 | 0.1188 | 0.0000 | 0.1341 | 0.0000 | 0.0920 | 0.0000 | 0.0012 | 0.0049 | 0.0132 | 0.0292 | 0.0679 | 0.1075 | 0.1161 | 0.1588 | 0.5012 | 17 | 22 | 29 | 46 | 89 | 180 | 301 | 457 | 675 | 0.0295 | 57.83 | 5.943 | 0.4328 | 143927.0 | 117000000 | 112000000000 | 121000000000000 | 0.4463 | 0.1845 | 0.0546 | 0.0038 | 0.1914 | 0.0093 | 0.2906 | 0.1053 | 0.1701 | 0.1693 | 0.1184 | 0.2109 | 0.1042 | 0.1922 | 0.0475 | 0.1153 | 0.0156 | 0.0952 | 0.0078 | 0.0987 | 0.0001 | 0.0005 | 0.0011 | 0.0005 | 0.0034 | 0.0014 | 0.0108 | 0.0082 | 0.0532 | 0.0501 | 0.0872 | 0.0742 | 0.0606 | 0.0519 | 0.0872 | 0.0802 | 0.6963 | 0.7330 | 0.0005 | 0.0004 | 0.0021 | 0.0008 | 0.0042 | 0.0052 | 0.0150 | 0.0185 | 0.0656 | 0.0707 | 0.1028 | 0.1137 | 0.0807 | 0.0882 | 0.1081 | 0.1140 | 0.6208 | 0.5885 | 0.0002 | 0.0016 | 0.0046 | 0.0142 | 0.0602 | 0.0943 | 0.0678 | 0.0986 | 0.6586 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 564 | 431 | | 338 | 1164 | 102.2 | 15.22 | 7.58 | 3.30 | 84 | 88 | 92 | 95 | 102 | 108 | 112 | 115 | 121 | 0.2259 | 263 | 0.523 | 92.70 | 19.72 | 2 | 0.8195 | 277 | 0.0741 | 0.65 | 2.916 | 0.7228 | 10676.7 | 1140000 | 124000000 | 13800000000 | 0.3677 | 0.2665 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0035 | 0.0000 | 0.0070 | 0.0090 | 0.0662 | 0.0448 | 0.1533 | 0.0985 | 0.0732 | 0.0507 | 0.1150 | 0.0836 | 0.5784 | 0.7134 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0063 | 0.0089 | 0.0508 | 0.0444 | 0.1111 | 0.0947 | 0.0381 | 0.0385 | 0.0730 | 0.0621 | 0.7175 | 0.7515 | 0.0000 | 0.0000 | 0.0357 | 0.0000 | 0.0357 | 1.0000 | 0.1071 | 0.0000 | 0.1786 | 0.0000 | 0.1786 | 0.0000 | 0.1429 | 0.0000 | 0.1071 | 0.0000 | 0.2143 | 0.0000 | 0.0059 | 0.0000 | 0.0000 | 0.0296 | 0.0710 | 0.0888 | 0.0888 | 0.0947 | 0.6213 | 5 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 10 | 0.1160 | 0.40 | 1.049 | 0.4095 | 68.4 | 808.275 | 13870.1 | 338018 | 0.5218 | 0.1263 | 0.0138 | 0.0000 | 0.1041 | 0.0030 | 0.2004 | 0.0099 | 0.2338 | 0.0338 | 0.1847 | 0.0746 | 0.1493 | 0.1014 | 0.0727 | 0.1690 | 0.0393 | 0.3052 | 0.0020 | 0.3032 | 0.0071 | 0.0000 | 0.0454 | 0.0000 | 0.0894 | 0.0055 | 0.1504 | 0.0193 | 0.1660 | 0.0654 | 0.1943 | 0.1096 | 0.1191 | 0.1436 | 0.1121 | 0.2818 | 0.1163 | 0.3748 | 0.2041 | 0.0875 | 0.1735 | 0.1250 | 0.0561 | 0.1250 | 0.0765 | 0.0500 | 0.1173 | 0.0625 | 0.1276 | 0.1750 | 0.0918 | 0.1625 | 0.0918 | 0.1000 | 0.0612 | 0.1125 | 0.0463 | 0.1305 | 0.1347 | 0.1705 | 0.1347 | 0.1200 | 0.0968 | 0.0758 | 0.0905 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1165 | 419 | | 423 | 1848 | 89.8 | 13.38 | 5.99 | 2.24 | 70 | 76 | 82 | 87 | 92 | 96 | 99 | 102 | 106 | 0.1580 | 292 | 0.987 | 101.21 | 28.84 | 2 | 0.5816 | 246 | 0.0855 | 0.62 | 2.720 | 0.7418 | 8238.7 | 771134 | 73500000 | 7110000000 | 0.4178 | 0.2216 | 0.0000 | 0.0000 | 0.0060 | 0.0000 | 0.0149 | 0.0000 | 0.0268 | 0.0071 | 0.0893 | 0.0567 | 0.1220 | 0.0946 | 0.1369 | 0.0520 | 0.1964 | 0.0827 | 0.4077 | 0.7069 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0109 | 0.0000 | 0.0218 | 0.0071 | 0.0708 | 0.0567 | 0.0627 | 0.0946 | 0.0518 | 0.0520 | 0.0681 | 0.0827 | 0.7084 | 0.7069 | 0.0968 | 0.0000 | 0.2581 | 0.0000 | 0.2581 | 0.0000 | 0.1613 | 0.0000 | 0.0968 | 0.0000 | 0.0968 | 0.0000 | 0.0323 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.0213 | 0.0383 | 0.0553 | 0.0596 | 0.0851 | 0.1532 | 0.5745 | 3 | 4 | 5 | 6 | 6 | 6 | 7 | 8 | 9 | 0.0815 | 0.39 | 0.827 | 0.2673 | 40.9 | 306.966 | 2499.9 | 21880.8 | 0.5165 | 0.1403 | 0.0116 | 0.0008 | 0.0474 | 0.0055 | 0.1063 | 0.0444 | 0.2358 | 0.1014 | 0.2716 | 0.1846 | 0.1884 | 0.2472 | 0.1011 | 0.2274 | 0.0316 | 0.1450 | 0.0063 | 0.0436 | 0.0000 | 0.0000 | 0.0041 | 0.0020 | 0.0186 | 0.0118 | 0.0592 | 0.0341 | 0.1171 | 0.1076 | 0.1860 | 0.1594 | 0.2404 | 0.2270 | 0.2424 | 0.2782 | 0.1322 | 0.1798 | 0.1036 | 0.3053 | 0.2490 | 0.2824 | 0.2829 | 0.1756 | 0.1972 | 0.0954 | 0.1056 | 0.0916 | 0.0418 | 0.0305 | 0.0179 | 0.0153 | 0.0020 | 0.0038 | 0.0000 | 0.0000 | 0.0026 | 0.0290 | 0.0729 | 0.1747 | 0.2186 | 0.2151 | 0.1449 | 0.1010 | 0.0413 |