High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 644 | 300 | | 381 | 806 | 12.1 | 3.51 | 5.40 | 1.98 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 17 | 0.3623 | 292 | 0.804 | 32.02 | 8.25 | 0 | 0.2283 | 87 | 0.0100 | 11.54 | 4.797 | 0.2819 | 158.7 | 2234.75 | 33514.1 | 530731 | 0.4187 | 0.2080 | 0.0000 | 0.0000 | 0.0459 | 0.0000 | 0.1429 | 0.0033 | 0.1837 | 0.0262 | 0.2143 | 0.1082 | 0.2245 | 0.1934 | 0.1071 | 0.1836 | 0.0663 | 0.2787 | 0.0153 | 0.2066 | 0.0000 | 0.0000 | 0.0179 | 0.0000 | 0.0286 | 0.0000 | 0.0536 | 0.0143 | 0.0929 | 0.0602 | 0.1071 | 0.0659 | 0.1464 | 0.1347 | 0.1929 | 0.2063 | 0.3607 | 0.5186 | 0.0238 | 0.0682 | 0.1310 | 0.2045 | 0.1310 | 0.1136 | 0.2262 | 0.1591 | 0.1667 | 0.1364 | 0.1548 | 0.2273 | 0.0595 | 0.0455 | 0.0833 | 0.0455 | 0.0238 | 0.0000 | 0.0094 | 0.0330 | 0.0377 | 0.0566 | 0.1226 | 0.1509 | 0.1462 | 0.2217 | 0.2217 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0262 | 8.53 | 4.026 | 0.3635 | 33.1 | 222.937 | 1630.58 | 12844 | 0.5218 | 0.1301 | 0.0340 | 0.0037 | 0.1671 | 0.0201 | 0.2125 | 0.0713 | 0.2351 | 0.1755 | 0.2153 | 0.2194 | 0.0963 | 0.2102 | 0.0397 | 0.1481 | 0.0000 | 0.1097 | 0.0000 | 0.0420 | 0.0014 | 0.0013 | 0.0029 | 0.0000 | 0.0203 | 0.0053 | 0.0695 | 0.0420 | 0.1462 | 0.1183 | 0.1650 | 0.1367 | 0.1838 | 0.1380 | 0.2489 | 0.2076 | 0.1621 | 0.3509 | 0.0355 | 0.1308 | 0.1450 | 0.2664 | 0.2367 | 0.2617 | 0.2426 | 0.1215 | 0.1538 | 0.1308 | 0.0947 | 0.0607 | 0.0562 | 0.0187 | 0.0266 | 0.0000 | 0.0089 | 0.0093 | 0.0018 | 0.0235 | 0.0868 | 0.1374 | 0.1953 | 0.2441 | 0.2080 | 0.0759 | 0.0271 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 845 | 391 | | 8714 | 28501 | 282.2 | 64.28 | 121.16 | 121.03 | 206 | 227 | 243 | 259 | 276 | 293 | 313 | 334 | 368 | 0.0454 | 1293 | 1.148 | 102.08 | 30.46 | 1 | 0.0270 | 235 | 0.0023 | 14.79 | 6.394 | 0.2854 | 83742.3 | 26100000 | 8530000000 | 2910000000000 | 0.4516 | 0.1999 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0048 | 0.0004 | 0.0140 | 0.0014 | 0.0658 | 0.0182 | 0.1361 | 0.0403 | 0.1469 | 0.0472 | 0.1796 | 0.0612 | 0.4515 | 0.8313 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0002 | 0.0057 | 0.0007 | 0.0319 | 0.0118 | 0.0595 | 0.0218 | 0.0612 | 0.0237 | 0.0824 | 0.0326 | 0.7570 | 0.9091 | 0.0044 | 0.0000 | 0.0062 | 0.0143 | 0.0187 | 0.0531 | 0.0704 | 0.0755 | 0.1172 | 0.1633 | 0.1509 | 0.2286 | 0.1010 | 0.0857 | 0.1415 | 0.1429 | 0.3897 | 0.2367 | 0.0005 | 0.0007 | 0.0074 | 0.0253 | 0.0763 | 0.1144 | 0.0817 | 0.1207 | 0.5730 | 16 | 28 | 45 | 64 | 86 | 111 | 142 | 189 | 270 | 0.0173 | 10.15 | 5.255 | 0.4896 | 29326.3 | 11100000 | 5770000000 | 3740000000000 | 0.5092 | 0.1670 | 0.0151 | 0.0015 | 0.0740 | 0.0061 | 0.1650 | 0.0287 | 0.1715 | 0.0720 | 0.1760 | 0.1555 | 0.1560 | 0.1872 | 0.1115 | 0.1505 | 0.0848 | 0.1481 | 0.0462 | 0.2505 | 0.0002 | 0.0005 | 0.0014 | 0.0011 | 0.0052 | 0.0033 | 0.0204 | 0.0126 | 0.0607 | 0.0488 | 0.0975 | 0.0843 | 0.0811 | 0.0687 | 0.1062 | 0.0968 | 0.6273 | 0.6839 | 0.0018 | 0.0015 | 0.0029 | 0.0027 | 0.0062 | 0.0087 | 0.0255 | 0.0332 | 0.0815 | 0.0912 | 0.1277 | 0.1335 | 0.0916 | 0.0982 | 0.1235 | 0.1301 | 0.5393 | 0.5010 | 0.0013 | 0.0021 | 0.0052 | 0.0239 | 0.0719 | 0.1113 | 0.0898 | 0.1163 | 0.5781 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 609 | 654 | | 7151 | 16942 | 197.2 | 47.67 | 158.72 | 128.62 | 142 | 158 | 169 | 180 | 191 | 204 | 217 | 235 | 262 | 0.0596 | 1009 | 1.165 | 114.14 | 40.26 | 1 | 0.0386 | 276 | 0.0010 | 44.53 | 7.179 | 0.1807 | 41154.1 | 9080000 | 2110000000 | 515000000000 | 0.4398 | 0.2146 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0034 | 0.0005 | 0.0225 | 0.0016 | 0.0918 | 0.0226 | 0.1658 | 0.0544 | 0.1623 | 0.0541 | 0.1830 | 0.0721 | 0.3699 | 0.7947 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0003 | 0.0087 | 0.0007 | 0.0377 | 0.0140 | 0.0650 | 0.0283 | 0.0655 | 0.0241 | 0.0987 | 0.0339 | 0.7223 | 0.8987 | 0.0043 | 0.0021 | 0.0080 | 0.0062 | 0.0217 | 0.0331 | 0.0810 | 0.1198 | 0.1389 | 0.1818 | 0.1975 | 0.2293 | 0.1172 | 0.1198 | 0.1404 | 0.1446 | 0.2909 | 0.1632 | 0.0015 | 0.0028 | 0.0067 | 0.0294 | 0.0781 | 0.1246 | 0.1136 | 0.1476 | 0.4957 | 29 | 50 | 73 | 98 | 124 | 154 | 195 | 255 | 340 | 0.0025 | 49.37 | 6.896 | 0.3087 | 41734.7 | 14900000 | 6570000000 | 3430000000000 | 0.4757 | 0.1683 | 0.0102 | 0.0005 | 0.0551 | 0.0051 | 0.1533 | 0.0172 | 0.1688 | 0.0526 | 0.1754 | 0.1321 | 0.1767 | 0.1793 | 0.1141 | 0.1494 | 0.0913 | 0.1597 | 0.0551 | 0.3041 | 0.0000 | 0.0002 | 0.0006 | 0.0008 | 0.0042 | 0.0018 | 0.0120 | 0.0073 | 0.0502 | 0.0359 | 0.0871 | 0.0632 | 0.0784 | 0.0546 | 0.1087 | 0.0842 | 0.6587 | 0.7522 | 0.0021 | 0.0007 | 0.0015 | 0.0035 | 0.0069 | 0.0106 | 0.0218 | 0.0308 | 0.0832 | 0.0946 | 0.1321 | 0.1464 | 0.1017 | 0.1114 | 0.1388 | 0.1415 | 0.5118 | 0.4604 | 0.0011 | 0.0012 | 0.0050 | 0.0180 | 0.0637 | 0.1167 | 0.0942 | 0.1257 | 0.5744 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 854 | 405 | | 7527 | 31665 | 388.4 | 72.66 | 93.45 | 141.02 | 301 | 326 | 347 | 364 | 382 | 400 | 421 | 447 | 487 | 0.0374 | 1185 | 1.088 | 108.58 | 28.32 | 1 | 0.0323 | 243 | 0.0008 | 48.68 | 7.360 | 0.1631 | 156148.0 | 64900000 | 27900000000 | 12400000000000 | 0.4021 | 0.2480 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0046 | 0.0001 | 0.0110 | 0.0014 | 0.0414 | 0.0136 | 0.1010 | 0.0353 | 0.0993 | 0.0248 | 0.1508 | 0.0388 | 0.5912 | 0.8859 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0001 | 0.0052 | 0.0005 | 0.0195 | 0.0099 | 0.0510 | 0.0234 | 0.0462 | 0.0107 | 0.0737 | 0.0159 | 0.8031 | 0.9394 | 0.0056 | 0.0138 | 0.0130 | 0.0826 | 0.0241 | 0.0872 | 0.0519 | 0.1193 | 0.1270 | 0.1560 | 0.1724 | 0.2294 | 0.1233 | 0.0917 | 0.1483 | 0.0734 | 0.3346 | 0.1468 | 0.0008 | 0.0025 | 0.0065 | 0.0239 | 0.0686 | 0.1113 | 0.0975 | 0.1231 | 0.5659 | 6 | 8 | 11 | 21 | 39 | 63 | 99 | 156 | 250 | 0.0635 | 9.53 | 4.513 | 0.5426 | 28619.4 | 17100000 | 15800000000 | 18600000000000 | 0.4450 | 0.1844 | 0.0328 | 0.0005 | 0.1395 | 0.0088 | 0.2204 | 0.0603 | 0.1624 | 0.1175 | 0.1549 | 0.1747 | 0.1262 | 0.2022 | 0.0836 | 0.1486 | 0.0471 | 0.1229 | 0.0331 | 0.1645 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0022 | 0.0027 | 0.0119 | 0.0124 | 0.0537 | 0.0399 | 0.0815 | 0.0673 | 0.0674 | 0.0542 | 0.0954 | 0.0807 | 0.6869 | 0.7423 | 0.0007 | 0.0007 | 0.0017 | 0.0008 | 0.0046 | 0.0050 | 0.0176 | 0.0205 | 0.0658 | 0.0826 | 0.1195 | 0.1283 | 0.0762 | 0.0818 | 0.1160 | 0.1209 | 0.5979 | 0.5594 | 0.0003 | 0.0015 | 0.0051 | 0.0174 | 0.0607 | 0.0986 | 0.0754 | 0.1077 | 0.6333 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 717 | 772 | | 5044 | 13779 | 301.7 | 59.20 | 210.76 | 220.75 | 231 | 249 | 265 | 280 | 295 | 312 | 331 | 354 | 385 | 0.0589 | 812 | 0.776 | 118.60 | 32.65 | 1 | 0.0632 | 319 | 0.0007 | 72.96 | 7.469 | 0.1451 | 94502.0 | 30700000 | 10300000000 | 3580000000000 | 0.4636 | 0.1931 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0000 | 0.0145 | 0.0006 | 0.0751 | 0.0121 | 0.1252 | 0.0311 | 0.1304 | 0.0313 | 0.1693 | 0.0459 | 0.4797 | 0.8791 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0044 | 0.0000 | 0.0323 | 0.0096 | 0.0650 | 0.0212 | 0.0617 | 0.0156 | 0.0939 | 0.0258 | 0.7425 | 0.9278 | 0.0060 | 0.0074 | 0.0072 | 0.0148 | 0.0241 | 0.0889 | 0.0869 | 0.1778 | 0.1351 | 0.1926 | 0.1966 | 0.2296 | 0.1230 | 0.1037 | 0.1460 | 0.1185 | 0.2750 | 0.0667 | 0.0004 | 0.0009 | 0.0051 | 0.0381 | 0.0908 | 0.1422 | 0.0934 | 0.1285 | 0.5004 | 12 | 16 | 29 | 71 | 138 | 216 | 302 | 388 | 517 | 0.0184 | 66.02 | 6.381 | 0.3575 | 93147.7 | 54300000 | 38200000000 | 31100000000000 | 0.5593 | 0.0982 | 0.0360 | 0.0028 | 0.1517 | 0.0183 | 0.2992 | 0.0785 | 0.1891 | 0.1391 | 0.1447 | 0.1813 | 0.0976 | 0.2120 | 0.0429 | 0.1411 | 0.0277 | 0.1141 | 0.0111 | 0.1128 | 0.0005 | 0.0000 | 0.0006 | 0.0013 | 0.0024 | 0.0029 | 0.0090 | 0.0067 | 0.0485 | 0.0391 | 0.0883 | 0.0705 | 0.0680 | 0.0561 | 0.1104 | 0.0882 | 0.6724 | 0.7352 | 0.0002 | 0.0007 | 0.0010 | 0.0007 | 0.0043 | 0.0064 | 0.0151 | 0.0203 | 0.0661 | 0.0835 | 0.1350 | 0.1546 | 0.0965 | 0.1018 | 0.1321 | 0.1450 | 0.5497 | 0.4870 | 0.0002 | 0.0009 | 0.0032 | 0.0112 | 0.0580 | 0.1055 | 0.0852 | 0.1259 | 0.6100 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 293 | 422 | | 7600 | 17600 | 391.5 | 79.06 | 96.65 | 175.15 | 294 | 323 | 346 | 368 | 387 | 407 | 428 | 454 | 494 | 0.0666 | 1173 | 1.027 | 120.93 | 40.26 | 1 | 0.0393 | 299 | 0.0010 | 42.54 | 7.175 | 0.1809 | 159521.0 | 67600000 | 29700000000 | 13600000000000 | 0.4253 | 0.2170 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0029 | 0.0001 | 0.0171 | 0.0012 | 0.0549 | 0.0162 | 0.1019 | 0.0305 | 0.1266 | 0.0305 | 0.1577 | 0.0455 | 0.5378 | 0.8759 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0070 | 0.0008 | 0.0228 | 0.0109 | 0.0451 | 0.0198 | 0.0570 | 0.0134 | 0.0686 | 0.0214 | 0.7973 | 0.9336 | 0.0076 | 0.0156 | 0.0143 | 0.0430 | 0.0227 | 0.0352 | 0.0714 | 0.1211 | 0.1294 | 0.1953 | 0.1723 | 0.2305 | 0.1445 | 0.1367 | 0.1437 | 0.0977 | 0.2941 | 0.1250 | 0.0016 | 0.0033 | 0.0068 | 0.0256 | 0.0698 | 0.1192 | 0.1121 | 0.1367 | 0.5248 | 7 | 8 | 10 | 12 | 15 | 25 | 57 | 139 | 334 | 0.1858 | 26.15 | 3.861 | 0.6358 | 40015.7 | 24500000 | 18000000000 | 15000000000000 | 0.4382 | 0.1915 | 0.0832 | 0.0054 | 0.2774 | 0.0380 | 0.2825 | 0.1739 | 0.1261 | 0.1618 | 0.0870 | 0.2101 | 0.0542 | 0.1540 | 0.0429 | 0.0936 | 0.0366 | 0.0713 | 0.0101 | 0.0918 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0011 | 0.0015 | 0.0121 | 0.0107 | 0.0607 | 0.0574 | 0.0962 | 0.0804 | 0.0626 | 0.0563 | 0.0962 | 0.0923 | 0.6700 | 0.7009 | 0.0000 | 0.0003 | 0.0005 | 0.0003 | 0.0023 | 0.0006 | 0.0143 | 0.0109 | 0.0696 | 0.0836 | 0.1222 | 0.1310 | 0.0703 | 0.0729 | 0.1126 | 0.1203 | 0.6081 | 0.5802 | 0.0000 | 0.0007 | 0.0012 | 0.0145 | 0.0655 | 0.1071 | 0.0700 | 0.1014 | 0.6396 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 857 | 519 | | 7896 | 25086 | 549.1 | 111.64 | 115.29 | 108.29 | 407 | 452 | 487 | 515 | 543 | 571 | 603 | 640 | 694 | 0.0453 | 1137 | 0.998 | 121.50 | 33.97 | 1 | 0.0384 | 303 | 0.0006 | 71.62 | 7.693 | 0.1462 | 313964.0 | 187000000 | 115000000000 | 73300000000000 | 0.4442 | 0.2062 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0110 | 0.0013 | 0.0526 | 0.0162 | 0.1198 | 0.0335 | 0.1264 | 0.0258 | 0.1582 | 0.0429 | 0.5295 | 0.8802 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0000 | 0.0247 | 0.0109 | 0.0576 | 0.0223 | 0.0544 | 0.0138 | 0.0738 | 0.0246 | 0.7850 | 0.9284 | 0.0055 | 0.0067 | 0.0079 | 0.0134 | 0.0259 | 0.0235 | 0.0715 | 0.0705 | 0.1155 | 0.1779 | 0.1595 | 0.2315 | 0.1147 | 0.1409 | 0.1304 | 0.1342 | 0.3692 | 0.2013 | 0.0003 | 0.0021 | 0.0045 | 0.0279 | 0.0760 | 0.1244 | 0.0942 | 0.1323 | 0.5384 | 14 | 19 | 30 | 51 | 80 | 116 | 158 | 205 | 271 | 0.0163 | 18.42 | 5.849 | 0.4162 | 25016.0 | 7180000 | 2480000000 | 993000000000 | 0.4965 | 0.1507 | 0.0497 | 0.0008 | 0.2062 | 0.0128 | 0.2854 | 0.1255 | 0.1474 | 0.1729 | 0.1169 | 0.1868 | 0.0873 | 0.1793 | 0.0490 | 0.1096 | 0.0336 | 0.0972 | 0.0245 | 0.1151 | 0.0003 | 0.0000 | 0.0008 | 0.0004 | 0.0022 | 0.0018 | 0.0130 | 0.0103 | 0.0633 | 0.0528 | 0.1135 | 0.0937 | 0.0729 | 0.0627 | 0.1138 | 0.0990 | 0.6201 | 0.6793 | 0.0006 | 0.0004 | 0.0013 | 0.0031 | 0.0045 | 0.0078 | 0.0266 | 0.0355 | 0.0880 | 0.1026 | 0.1507 | 0.1609 | 0.0929 | 0.1075 | 0.1339 | 0.1393 | 0.5016 | 0.4429 | 0.0004 | 0.0013 | 0.0028 | 0.0194 | 0.0737 | 0.1338 | 0.0833 | 0.1256 | 0.5598 | ||
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 735 | 770 | | 6091 | 18694 | 277.5 | 59.08 | 146.13 | 189.54 | 207 | 227 | 242 | 257 | 270 | 286 | 303 | 325 | 360 | 0.0517 | 966 | 1.132 | 134.38 | 47.43 | 1 | 0.0545 | 332 | 0.0007 | 64.70 | 7.464 | 0.1528 | 80490.5 | 24400000 | 7720000000 | 2550000000000 | 0.4323 | 0.2199 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0000 | 0.0154 | 0.0014 | 0.0654 | 0.0175 | 0.1429 | 0.0415 | 0.1509 | 0.0382 | 0.1728 | 0.0693 | 0.4499 | 0.8321 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0079 | 0.0003 | 0.0304 | 0.0134 | 0.0630 | 0.0205 | 0.0642 | 0.0152 | 0.0902 | 0.0304 | 0.7430 | 0.9203 | 0.0019 | 0.0132 | 0.0096 | 0.0166 | 0.0182 | 0.0795 | 0.0738 | 0.1358 | 0.1381 | 0.1821 | 0.1937 | 0.2318 | 0.1035 | 0.0762 | 0.1505 | 0.1126 | 0.3106 | 0.1523 | 0.0018 | 0.0033 | 0.0109 | 0.0301 | 0.0733 | 0.1309 | 0.1099 | 0.1193 | 0.5205 | 9 | 11 | 12 | 15 | 30 | 105 | 203 | 301 | 416 | 0.1325 | 29.91 | 4.805 | 0.5468 | 57276.7 | 29800000 | 18600000000 | 13400000000000 | 0.5440 | 0.1256 | 0.0714 | 0.0031 | 0.2395 | 0.0243 | 0.3145 | 0.1494 | 0.1559 | 0.2050 | 0.1263 | 0.2205 | 0.0462 | 0.1803 | 0.0314 | 0.0985 | 0.0096 | 0.0681 | 0.0052 | 0.0508 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0006 | 0.0006 | 0.0059 | 0.0032 | 0.0420 | 0.0353 | 0.0761 | 0.0653 | 0.0627 | 0.0511 | 0.0960 | 0.0756 | 0.7167 | 0.7688 | 0.0002 | 0.0000 | 0.0007 | 0.0009 | 0.0015 | 0.0021 | 0.0100 | 0.0122 | 0.0607 | 0.0697 | 0.1088 | 0.1264 | 0.0830 | 0.0840 | 0.1178 | 0.1284 | 0.6173 | 0.5762 | 0.0000 | 0.0004 | 0.0006 | 0.0073 | 0.0536 | 0.0927 | 0.0730 | 0.1036 | 0.6688 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 376 | 455 | | 8612 | 19511 | 469.8 | 86.38 | 153.43 | 207.66 | 366 | 398 | 421 | 442 | 462 | 481 | 504 | 535 | 586 | 0.0560 | 1092 | 1.054 | 96.75 | 36.14 | 2 | 0.0303 | 261 | 0.0021 | 17.56 | 6.482 | 0.2579 | 228217.0 | 115000000 | 59600000000 | 32000000000000 | 0.4229 | 0.2282 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0001 | 0.0076 | 0.0005 | 0.0416 | 0.0131 | 0.0841 | 0.0274 | 0.0978 | 0.0207 | 0.1278 | 0.0313 | 0.6396 | 0.9068 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0041 | 0.0000 | 0.0211 | 0.0100 | 0.0414 | 0.0175 | 0.0481 | 0.0110 | 0.0610 | 0.0179 | 0.8237 | 0.9436 | 0.0043 | 0.0036 | 0.0120 | 0.0109 | 0.0197 | 0.0217 | 0.0557 | 0.0833 | 0.1259 | 0.1304 | 0.1430 | 0.2319 | 0.1062 | 0.1196 | 0.1233 | 0.1159 | 0.4101 | 0.2826 | 0.0015 | 0.0043 | 0.0089 | 0.0317 | 0.0735 | 0.1259 | 0.1036 | 0.1315 | 0.5193 | 11 | 13 | 18 | 30 | 60 | 112 | 179 | 264 | 423 | 0.0683 | 25.53 | 5.187 | 0.5116 | 66658.4 | 44800000 | 39000000000 | 40100000000000 | 0.5736 | 0.1127 | 0.0353 | 0.0020 | 0.1686 | 0.0088 | 0.3001 | 0.0775 | 0.1811 | 0.1460 | 0.1407 | 0.2098 | 0.0974 | 0.2095 | 0.0444 | 0.1320 | 0.0256 | 0.1163 | 0.0068 | 0.0981 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0009 | 0.0008 | 0.0093 | 0.0073 | 0.0635 | 0.0515 | 0.0934 | 0.0789 | 0.0696 | 0.0596 | 0.1069 | 0.0928 | 0.6562 | 0.7087 | 0.0009 | 0.0006 | 0.0016 | 0.0028 | 0.0024 | 0.0028 | 0.0164 | 0.0188 | 0.0739 | 0.0858 | 0.1294 | 0.1377 | 0.0880 | 0.0928 | 0.1272 | 0.1341 | 0.5603 | 0.5246 | 0.0002 | 0.0006 | 0.0021 | 0.0135 | 0.0685 | 0.1068 | 0.0784 | 0.1212 | 0.6087 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 318 | 872 | | 12186 | 25790 | 350.1 | 84.35 | 180.74 | 231.33 | 250 | 278 | 300 | 319 | 340 | 362 | 386 | 419 | 463 | 0.0459 | 1185 | 1.241 | 90.52 | 37.58 | 1 | 0.0197 | 240 | 0.0006 | 79.84 | 7.705 | 0.1428 | 129698.0 | 50800000 | 21000000000 | 9160000000000 | 0.4637 | 0.1985 | 0.0008 | 0.0000 | 0.0050 | 0.0002 | 0.0093 | 0.0019 | 0.0269 | 0.0039 | 0.0810 | 0.0184 | 0.1487 | 0.0417 | 0.1625 | 0.0489 | 0.1712 | 0.0732 | 0.3947 | 0.8118 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0020 | 0.0001 | 0.0091 | 0.0003 | 0.0330 | 0.0101 | 0.0662 | 0.0219 | 0.0745 | 0.0199 | 0.0941 | 0.0344 | 0.7203 | 0.9133 | 0.0050 | 0.0088 | 0.0083 | 0.0113 | 0.0190 | 0.0479 | 0.0690 | 0.1614 | 0.1467 | 0.1589 | 0.1789 | 0.2320 | 0.1149 | 0.1236 | 0.1471 | 0.1097 | 0.3112 | 0.1463 | 0.0009 | 0.0031 | 0.0086 | 0.0355 | 0.0810 | 0.1311 | 0.1118 | 0.1336 | 0.4943 | 10 | 15 | 25 | 45 | 80 | 130 | 204 | 324 | 514 | 0.0440 | 29.42 | 5.543 | 0.4890 | 86176.2 | 59000000 | 49700000000 | 48200000000000 | 0.4861 | 0.1546 | 0.0520 | 0.0023 | 0.1701 | 0.0129 | 0.2665 | 0.0966 | 0.1459 | 0.1378 | 0.1201 | 0.1935 | 0.1172 | 0.1886 | 0.0605 | 0.1155 | 0.0372 | 0.1007 | 0.0305 | 0.1521 | 0.0003 | 0.0004 | 0.0012 | 0.0006 | 0.0023 | 0.0023 | 0.0133 | 0.0093 | 0.0591 | 0.0486 | 0.0997 | 0.0816 | 0.0694 | 0.0558 | 0.1037 | 0.0915 | 0.6512 | 0.7099 | 0.0005 | 0.0003 | 0.0007 | 0.0026 | 0.0046 | 0.0032 | 0.0156 | 0.0218 | 0.0784 | 0.0855 | 0.1293 | 0.1333 | 0.0752 | 0.0852 | 0.1163 | 0.1277 | 0.5793 | 0.5404 | 0.0006 | 0.0014 | 0.0033 | 0.0161 | 0.0656 | 0.1205 | 0.0715 | 0.1126 | 0.6084 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 781 | 933 | | 4650 | 7671 | 149.2 | 35.80 | 272.55 | 157.57 | 110 | 120 | 127 | 134 | 142 | 151 | 162 | 176 | 198 | 0.0948 | 727 | 1.075 | 97.75 | 27.80 | 1 | 0.0520 | 242 | 0.0020 | 26.81 | 6.558 | 0.2363 | 23531.1 | 3940000 | 699000000 | 132000000000 | 0.4493 | 0.1999 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0104 | 0.0002 | 0.0338 | 0.0009 | 0.0898 | 0.0243 | 0.1628 | 0.0471 | 0.1597 | 0.0468 | 0.1837 | 0.0695 | 0.3577 | 0.8111 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0002 | 0.0118 | 0.0004 | 0.0454 | 0.0150 | 0.0668 | 0.0232 | 0.0778 | 0.0163 | 0.1088 | 0.0306 | 0.6864 | 0.9142 | 0.0023 | 0.0030 | 0.0092 | 0.0060 | 0.0358 | 0.0329 | 0.0796 | 0.0928 | 0.1476 | 0.1707 | 0.1857 | 0.2335 | 0.1153 | 0.1138 | 0.1361 | 0.1707 | 0.2884 | 0.1766 | 0.0020 | 0.0035 | 0.0111 | 0.0308 | 0.0968 | 0.1402 | 0.1160 | 0.1452 | 0.4544 | 91 | 134 | 171 | 208 | 247 | 291 | 338 | 395 | 486 | 0.0007 | 96.75 | 7.538 | 0.1758 | 99105.9 | 44100000 | 22800000000 | 13300000000000 | 0.5485 | 0.1214 | 0.0151 | 0.0008 | 0.0764 | 0.0058 | 0.1871 | 0.0233 | 0.1861 | 0.0595 | 0.2027 | 0.1375 | 0.1554 | 0.2135 | 0.0941 | 0.1857 | 0.0520 | 0.1666 | 0.0312 | 0.2074 | 0.0009 | 0.0002 | 0.0030 | 0.0007 | 0.0077 | 0.0036 | 0.0219 | 0.0100 | 0.0743 | 0.0552 | 0.1272 | 0.1019 | 0.1078 | 0.0886 | 0.1429 | 0.1166 | 0.5144 | 0.6232 | 0.0008 | 0.0053 | 0.0106 | 0.0148 | 0.0203 | 0.0373 | 0.0519 | 0.0841 | 0.1339 | 0.1587 | 0.1729 | 0.1829 | 0.1303 | 0.1533 | 0.1652 | 0.1385 | 0.3141 | 0.2250 | 0.0009 | 0.0051 | 0.0146 | 0.0363 | 0.0991 | 0.1479 | 0.1303 | 0.1511 | 0.4148 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 786 | 723 | | 4403 | 10505 | 156.8 | 37.21 | 158.32 | 156.07 | 111 | 125 | 136 | 145 | 154 | 163 | 173 | 187 | 207 | 0.0730 | 767 | 1.082 | 105.15 | 39.01 | 1 | 0.0620 | 273 | 0.0017 | 27.23 | 6.665 | 0.2280 | 25980.4 | 4530000 | 831000000 | 159000000000 | 0.4286 | 0.2358 | 0.0007 | 0.0000 | 0.0045 | 0.0003 | 0.0138 | 0.0018 | 0.0302 | 0.0040 | 0.0832 | 0.0260 | 0.1542 | 0.0510 | 0.1486 | 0.0545 | 0.1725 | 0.0808 | 0.3923 | 0.7817 | 0.0000 | 0.0000 | 0.0009 | 0.0002 | 0.0009 | 0.0002 | 0.0068 | 0.0009 | 0.0392 | 0.0176 | 0.0717 | 0.0309 | 0.0697 | 0.0248 | 0.0958 | 0.0405 | 0.7151 | 0.8849 | 0.0024 | 0.0182 | 0.0155 | 0.0146 | 0.0274 | 0.0474 | 0.0764 | 0.1314 | 0.1372 | 0.1788 | 0.2076 | 0.2336 | 0.1313 | 0.0985 | 0.1396 | 0.1314 | 0.2625 | 0.1460 | 0.0024 | 0.0015 | 0.0068 | 0.0336 | 0.0973 | 0.1357 | 0.1051 | 0.1367 | 0.4810 | 15 | 27 | 45 | 75 | 110 | 150 | 199 | 265 | 380 | 0.0051 | 65.67 | 6.760 | 0.3104 | 49420.1 | 21200000 | 11000000000 | 6460000000000 | 0.5076 | 0.1389 | 0.0172 | 0.0010 | 0.0968 | 0.0078 | 0.2177 | 0.0413 | 0.1765 | 0.0889 | 0.1820 | 0.1633 | 0.1360 | 0.1965 | 0.0859 | 0.1508 | 0.0522 | 0.1403 | 0.0357 | 0.2100 | 0.0006 | 0.0000 | 0.0015 | 0.0009 | 0.0038 | 0.0042 | 0.0125 | 0.0116 | 0.0563 | 0.0446 | 0.0987 | 0.0767 | 0.0747 | 0.0616 | 0.1081 | 0.0892 | 0.6439 | 0.7113 | 0.0009 | 0.0015 | 0.0030 | 0.0036 | 0.0093 | 0.0109 | 0.0246 | 0.0318 | 0.0818 | 0.0982 | 0.1325 | 0.1383 | 0.0971 | 0.0985 | 0.1250 | 0.1438 | 0.5259 | 0.4734 | 0.0002 | 0.0017 | 0.0057 | 0.0214 | 0.0664 | 0.1176 | 0.0927 | 0.1161 | 0.5782 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 923 | 124 | | 725 | 2122 | 76.0 | 19.18 | 87.85 | 150.35 | 55 | 62 | 66 | 70 | 74 | 78 | 82 | 89 | 98 | 0.1555 | 330 | 1.062 | 83.67 | 27.73 | 1 | 0.3007 | 218 | 0.0059 | 12.27 | 5.382 | 0.3021 | 6143.7 | 529049 | 48700000 | 4800000000 | 0.4598 | 0.1774 | 0.0021 | 0.0000 | 0.0105 | 0.0000 | 0.0316 | 0.0062 | 0.0547 | 0.0170 | 0.1116 | 0.0602 | 0.1495 | 0.0802 | 0.1558 | 0.0725 | 0.1811 | 0.1065 | 0.3032 | 0.6574 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0100 | 0.0014 | 0.0067 | 0.0029 | 0.0585 | 0.0432 | 0.1137 | 0.0748 | 0.0870 | 0.0489 | 0.1421 | 0.0691 | 0.5803 | 0.7597 | 0.0081 | 0.0213 | 0.0488 | 0.0000 | 0.0407 | 0.0638 | 0.0894 | 0.1489 | 0.2602 | 0.2340 | 0.1057 | 0.2340 | 0.1545 | 0.0638 | 0.1463 | 0.0851 | 0.1463 | 0.1489 | 0.0000 | 0.0030 | 0.0302 | 0.0604 | 0.1329 | 0.1813 | 0.1390 | 0.1601 | 0.2931 | 14 | 17 | 20 | 25 | 38 | 53 | 73 | 106 | 191 | 0.0472 | 42.92 | 4.329 | 0.5495 | 30310.8 | 21700000 | 20800000000 | 23000000000000 | 0.5356 | 0.1304 | 0.0400 | 0.0000 | 0.1778 | 0.0200 | 0.1689 | 0.0798 | 0.2267 | 0.1098 | 0.1289 | 0.1377 | 0.1333 | 0.1896 | 0.0978 | 0.1337 | 0.0178 | 0.1018 | 0.0089 | 0.2275 | 0.0015 | 0.0000 | 0.0122 | 0.0000 | 0.0198 | 0.0141 | 0.0517 | 0.0387 | 0.0836 | 0.0810 | 0.1049 | 0.1244 | 0.1094 | 0.0845 | 0.1261 | 0.1315 | 0.4909 | 0.5258 | 0.0000 | 0.0028 | 0.0139 | 0.0057 | 0.0254 | 0.0256 | 0.0647 | 0.0427 | 0.1062 | 0.1225 | 0.1201 | 0.1595 | 0.1178 | 0.0798 | 0.1293 | 0.1681 | 0.4226 | 0.3932 | 0.0019 | 0.0130 | 0.0093 | 0.0484 | 0.1043 | 0.1229 | 0.0987 | 0.1378 | 0.4637 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 819 | 837 | | 4077 | 7402 | 164.0 | 45.49 | 281.51 | 208.60 | 106 | 126 | 139 | 150 | 161 | 172 | 185 | 201 | 225 | 0.0809 | 599 | 0.666 | 68.59 | 22.56 | 2 | 0.0518 | 211 | 0.0013 | 30.19 | 6.879 | 0.2104 | 28976.0 | 5470000 | 1100000000 | 232000000000 | 0.4785 | 0.1795 | 0.0028 | 0.0000 | 0.0032 | 0.0006 | 0.0065 | 0.0020 | 0.0341 | 0.0061 | 0.1138 | 0.0314 | 0.1876 | 0.0802 | 0.1618 | 0.0709 | 0.1834 | 0.0994 | 0.3069 | 0.7095 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0019 | 0.0005 | 0.0081 | 0.0026 | 0.0430 | 0.0195 | 0.0783 | 0.0445 | 0.0608 | 0.0306 | 0.0935 | 0.0458 | 0.7126 | 0.8562 | 0.0043 | 0.0113 | 0.0185 | 0.0226 | 0.0120 | 0.0452 | 0.0663 | 0.1271 | 0.1261 | 0.1582 | 0.1815 | 0.2345 | 0.1239 | 0.1356 | 0.1424 | 0.0989 | 0.3250 | 0.1667 | 0.0015 | 0.0021 | 0.0072 | 0.0355 | 0.0762 | 0.1340 | 0.1061 | 0.1175 | 0.5198 | 41 | 86 | 136 | 190 | 247 | 308 | 370 | 448 | 564 | 0.0018 | 128.90 | 7.431 | 0.1991 | 122752.0 | 67400000 | 43400000000 | 31600000000000 | 0.5494 | 0.1250 | 0.0218 | 0.0004 | 0.1102 | 0.0047 | 0.2408 | 0.0505 | 0.1748 | 0.0920 | 0.1769 | 0.1749 | 0.1363 | 0.2080 | 0.0798 | 0.1531 | 0.0428 | 0.1385 | 0.0167 | 0.1778 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0011 | 0.0151 | 0.0089 | 0.0627 | 0.0498 | 0.1204 | 0.0924 | 0.0929 | 0.0759 | 0.1327 | 0.1043 | 0.5715 | 0.6676 | 0.0000 | 0.0020 | 0.0042 | 0.0036 | 0.0096 | 0.0137 | 0.0301 | 0.0493 | 0.1131 | 0.1301 | 0.1521 | 0.1876 | 0.1212 | 0.1256 | 0.1613 | 0.1520 | 0.4083 | 0.3360 | 0.0015 | 0.0024 | 0.0049 | 0.0182 | 0.0809 | 0.1469 | 0.1031 | 0.1338 | 0.5082 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 840 | 632 | | 7599 | 25331 | 439.9 | 83.79 | 168.72 | 276.45 | 340 | 369 | 390 | 410 | 429 | 450 | 476 | 508 | 555 | 0.0492 | 1247 | 1.002 | 122.50 | 43.46 | 1 | 0.0425 | 323 | 0.0006 | 77.97 | 7.638 | 0.1430 | 200554.0 | 94700000 | 46300000000 | 23400000000000 | 0.4550 | 0.1957 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0026 | 0.0000 | 0.0094 | 0.0007 | 0.0535 | 0.0144 | 0.1165 | 0.0319 | 0.1324 | 0.0357 | 0.1602 | 0.0471 | 0.5253 | 0.8703 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0278 | 0.0111 | 0.0578 | 0.0182 | 0.0625 | 0.0137 | 0.0881 | 0.0211 | 0.7604 | 0.9358 | 0.0025 | 0.0077 | 0.0101 | 0.0193 | 0.0126 | 0.0386 | 0.0666 | 0.2278 | 0.1265 | 0.2162 | 0.1678 | 0.2355 | 0.1273 | 0.1042 | 0.1669 | 0.0965 | 0.3196 | 0.0541 | 0.0012 | 0.0026 | 0.0096 | 0.0417 | 0.0858 | 0.1214 | 0.1033 | 0.1219 | 0.5125 | 6 | 7 | 9 | 11 | 16 | 45 | 143 | 328 | 583 | 0.1315 | 51.22 | 4.587 | 0.5228 | 104886.0 | 87500000 | 85800000000 | 94300000000000 | 0.5042 | 0.1314 | 0.1174 | 0.0045 | 0.3070 | 0.0508 | 0.2798 | 0.2324 | 0.1277 | 0.2165 | 0.1108 | 0.1884 | 0.0404 | 0.1303 | 0.0113 | 0.0944 | 0.0038 | 0.0477 | 0.0019 | 0.0350 | 0.0001 | 0.0001 | 0.0012 | 0.0004 | 0.0026 | 0.0011 | 0.0093 | 0.0084 | 0.0522 | 0.0465 | 0.0772 | 0.0740 | 0.0532 | 0.0513 | 0.0848 | 0.0734 | 0.7194 | 0.7448 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0021 | 0.0027 | 0.0093 | 0.0091 | 0.0560 | 0.0627 | 0.0918 | 0.1001 | 0.0656 | 0.0705 | 0.1066 | 0.1206 | 0.6678 | 0.6332 | 0.0003 | 0.0015 | 0.0032 | 0.0089 | 0.0529 | 0.0819 | 0.0600 | 0.0898 | 0.7015 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 826 | 768 | | 6744 | 16336 | 268.2 | 71.69 | 141.22 | 168.95 | 172 | 220 | 244 | 260 | 275 | 290 | 307 | 325 | 352 | 0.0586 | 958 | 0.774 | 134.30 | 33.11 | 3 | 0.0550 | 371 | 0.0010 | 38.65 | 7.160 | 0.1905 | 77081.5 | 23200000 | 7220000000 | 2320000000000 | 0.3771 | 0.2521 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0047 | 0.0000 | 0.0202 | 0.0010 | 0.0641 | 0.0201 | 0.1133 | 0.0421 | 0.1271 | 0.0409 | 0.1690 | 0.0603 | 0.5009 | 0.8356 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0022 | 0.0003 | 0.0193 | 0.0134 | 0.0351 | 0.0215 | 0.0430 | 0.0137 | 0.0639 | 0.0228 | 0.8363 | 0.9283 | 0.0020 | 0.0031 | 0.0094 | 0.0282 | 0.0201 | 0.0627 | 0.0602 | 0.1818 | 0.1145 | 0.1567 | 0.1667 | 0.2382 | 0.1245 | 0.1160 | 0.1506 | 0.1097 | 0.3521 | 0.1034 | 0.0005 | 0.0016 | 0.0054 | 0.0231 | 0.0549 | 0.0995 | 0.1012 | 0.1118 | 0.6018 | 11 | 13 | 17 | 33 | 74 | 117 | 174 | 256 | 384 | 0.1123 | 13.02 | 4.544 | 0.6051 | 48483.6 | 23400000 | 14000000000 | 9870000000000 | 0.3529 | 0.3072 | 0.0233 | 0.0006 | 0.0993 | 0.0098 | 0.1771 | 0.0540 | 0.1646 | 0.0816 | 0.1538 | 0.1403 | 0.1514 | 0.1788 | 0.0946 | 0.1438 | 0.0814 | 0.1444 | 0.0545 | 0.2467 | 0.0000 | 0.0000 | 0.0010 | 0.0014 | 0.0024 | 0.0015 | 0.0118 | 0.0068 | 0.0392 | 0.0287 | 0.0668 | 0.0517 | 0.0535 | 0.0373 | 0.0764 | 0.0617 | 0.7488 | 0.8108 | 0.0006 | 0.0011 | 0.0012 | 0.0025 | 0.0052 | 0.0039 | 0.0226 | 0.0215 | 0.0569 | 0.0753 | 0.0967 | 0.1142 | 0.0841 | 0.1007 | 0.1157 | 0.1304 | 0.6171 | 0.5504 | 0.0003 | 0.0014 | 0.0036 | 0.0128 | 0.0544 | 0.0778 | 0.0679 | 0.0958 | 0.6859 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 357 | 710 | | 4921 | 10409 | 582.7 | 104.04 | 163.34 | 169.37 | 446 | 495 | 525 | 552 | 579 | 603 | 634 | 667 | 722 | 0.0790 | 822 | 1.185 | 96.46 | 39.82 | 1 | 0.0528 | 260 | 0.0007 | 60.83 | 7.459 | 0.1592 | 350308.0 | 217000000 | 138000000000 | 90400000000000 | 0.4237 | 0.2197 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0017 | 0.0004 | 0.0084 | 0.0015 | 0.0427 | 0.0174 | 0.0858 | 0.0245 | 0.0936 | 0.0272 | 0.1375 | 0.0367 | 0.6295 | 0.8923 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0031 | 0.0002 | 0.0252 | 0.0151 | 0.0417 | 0.0191 | 0.0370 | 0.0165 | 0.0620 | 0.0242 | 0.8301 | 0.9248 | 0.0075 | 0.0326 | 0.0090 | 0.0000 | 0.0271 | 0.0761 | 0.0827 | 0.1739 | 0.1203 | 0.1739 | 0.1399 | 0.2391 | 0.1068 | 0.1413 | 0.1053 | 0.1087 | 0.4015 | 0.0543 | 0.0017 | 0.0034 | 0.0029 | 0.0253 | 0.0623 | 0.1077 | 0.1098 | 0.1355 | 0.5513 | 11 | 14 | 21 | 52 | 104 | 160 | 229 | 315 | 422 | 0.0230 | 43.80 | 6.033 | 0.3963 | 55363.2 | 23600000 | 11400000000 | 6020000000000 | 0.5634 | 0.1337 | 0.0386 | 0.0005 | 0.1929 | 0.0101 | 0.2671 | 0.0648 | 0.1977 | 0.1411 | 0.1244 | 0.2046 | 0.0839 | 0.1945 | 0.0473 | 0.1177 | 0.0260 | 0.1172 | 0.0222 | 0.1494 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0024 | 0.0004 | 0.0120 | 0.0066 | 0.0468 | 0.0368 | 0.0843 | 0.0643 | 0.0646 | 0.0509 | 0.1058 | 0.0885 | 0.6839 | 0.7518 | 0.0008 | 0.0003 | 0.0011 | 0.0016 | 0.0036 | 0.0038 | 0.0149 | 0.0166 | 0.0618 | 0.0787 | 0.1118 | 0.1234 | 0.0845 | 0.0918 | 0.1220 | 0.1321 | 0.5995 | 0.5516 | 0.0005 | 0.0010 | 0.0027 | 0.0124 | 0.0553 | 0.0981 | 0.0694 | 0.1131 | 0.6476 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 974 | 491 | | 2075 | 6138 | 79.2 | 16.85 | 226.62 | 224.68 | 59 | 65 | 70 | 74 | 77 | 82 | 86 | 93 | 102 | 0.0632 | 388 | 0.768 | 127.88 | 34.79 | 1 | 0.1566 | 325 | 0.0032 | 15.64 | 6.011 | 0.2726 | 6562.2 | 567309 | 51100000 | 4800000000 | 0.4688 | 0.1916 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0073 | 0.0005 | 0.0278 | 0.0010 | 0.0805 | 0.0234 | 0.1426 | 0.0426 | 0.1500 | 0.0483 | 0.2004 | 0.0701 | 0.3899 | 0.8141 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0063 | 0.0000 | 0.0322 | 0.0138 | 0.0679 | 0.0256 | 0.0621 | 0.0177 | 0.1059 | 0.0290 | 0.7238 | 0.9140 | 0.0081 | 0.0370 | 0.0270 | 0.0278 | 0.0377 | 0.0926 | 0.0916 | 0.0833 | 0.1456 | 0.1759 | 0.1806 | 0.2407 | 0.1294 | 0.1204 | 0.1240 | 0.1852 | 0.2561 | 0.0370 | 0.0030 | 0.0071 | 0.0163 | 0.0346 | 0.0925 | 0.1209 | 0.1189 | 0.1423 | 0.4644 | 24 | 43 | 68 | 98 | 138 | 204 | 294 | 397 | 550 | 0.0072 | 49.76 | 6.356 | 0.3422 | 101826.0 | 62200000 | 45000000000 | 36400000000000 | 0.4500 | 0.1910 | 0.0311 | 0.0000 | 0.1627 | 0.0071 | 0.2825 | 0.0767 | 0.1686 | 0.1526 | 0.1361 | 0.1859 | 0.1124 | 0.2314 | 0.0503 | 0.1313 | 0.0355 | 0.0987 | 0.0207 | 0.1164 | 0.0008 | 0.0000 | 0.0023 | 0.0013 | 0.0011 | 0.0016 | 0.0106 | 0.0107 | 0.0513 | 0.0417 | 0.1124 | 0.1059 | 0.0724 | 0.0672 | 0.1116 | 0.0820 | 0.6376 | 0.6897 | 0.0000 | 0.0012 | 0.0005 | 0.0030 | 0.0056 | 0.0077 | 0.0192 | 0.0195 | 0.0709 | 0.0936 | 0.1478 | 0.1647 | 0.1063 | 0.1043 | 0.1184 | 0.1345 | 0.5314 | 0.4716 | 0.0004 | 0.0013 | 0.0053 | 0.0149 | 0.0605 | 0.1329 | 0.0925 | 0.1136 | 0.5785 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 177 | 313 | | 5638 | 13933 | 398.6 | 102.35 | 102.66 | 164.28 | 278 | 312 | 338 | 363 | 391 | 418 | 444 | 477 | 530 | 0.0646 | 900 | 1.105 | 128.16 | 40.36 | 1 | 0.0566 | 319 | 0.0011 | 32.90 | 7.036 | 0.2099 | 169382.0 | 76400000 | 36500000000 | 18500000000000 | 0.3917 | 0.2443 | 0.0000 | 0.0002 | 0.0018 | 0.0000 | 0.0052 | 0.0006 | 0.0231 | 0.0041 | 0.0686 | 0.0246 | 0.1196 | 0.0553 | 0.1310 | 0.0452 | 0.1734 | 0.0712 | 0.4774 | 0.7988 | 0.0000 | 0.0002 | 0.0007 | 0.0000 | 0.0025 | 0.0004 | 0.0080 | 0.0026 | 0.0243 | 0.0159 | 0.0491 | 0.0316 | 0.0505 | 0.0232 | 0.0757 | 0.0338 | 0.7892 | 0.8923 | 0.0054 | 0.0078 | 0.0045 | 0.0207 | 0.0118 | 0.0181 | 0.0570 | 0.0622 | 0.1230 | 0.1425 | 0.1203 | 0.2409 | 0.1401 | 0.1295 | 0.1528 | 0.1529 | 0.3852 | 0.2254 | 0.0011 | 0.0011 | 0.0023 | 0.0196 | 0.0495 | 0.1072 | 0.0966 | 0.1076 | 0.6149 | 10 | 13 | 19 | 31 | 50 | 75 | 104 | 145 | 221 | 0.0586 | 9.85 | 4.528 | 0.5850 | 37525.9 | 28000000 | 28100000000 | 32100000000000 | 0.6066 | 0.1047 | 0.0130 | 0.0014 | 0.0691 | 0.0060 | 0.1943 | 0.0246 | 0.2038 | 0.0773 | 0.1991 | 0.1586 | 0.1471 | 0.2025 | 0.0939 | 0.1627 | 0.0585 | 0.1518 | 0.0213 | 0.2151 | 0.0004 | 0.0002 | 0.0023 | 0.0006 | 0.0041 | 0.0022 | 0.0209 | 0.0180 | 0.0638 | 0.0512 | 0.0976 | 0.0888 | 0.0749 | 0.0667 | 0.1049 | 0.0915 | 0.6311 | 0.6808 | 0.0012 | 0.0036 | 0.0023 | 0.0047 | 0.0092 | 0.0118 | 0.0286 | 0.0383 | 0.0754 | 0.0777 | 0.1265 | 0.1310 | 0.0826 | 0.0917 | 0.1129 | 0.1167 | 0.5614 | 0.5245 | 0.0014 | 0.0033 | 0.0064 | 0.0226 | 0.0683 | 0.1045 | 0.0824 | 0.1106 | 0.6005 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 558 | 297 | | 5154 | 21541 | 500.5 | 100.92 | 62.27 | 98.68 | 379 | 413 | 441 | 465 | 489 | 516 | 545 | 583 | 643 | 0.0452 | 974 | 1.154 | 82.42 | 31.26 | 1 | 0.0415 | 214 | 0.0008 | 54.34 | 7.369 | 0.1710 | 260702.0 | 141000000 | 79400000000 | 46200000000000 | 0.4202 | 0.2271 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0017 | 0.0002 | 0.0098 | 0.0012 | 0.0500 | 0.0161 | 0.1015 | 0.0368 | 0.0980 | 0.0279 | 0.1322 | 0.0328 | 0.6056 | 0.8850 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0006 | 0.0245 | 0.0117 | 0.0493 | 0.0242 | 0.0433 | 0.0125 | 0.0646 | 0.0189 | 0.8118 | 0.9320 | 0.0012 | 0.0000 | 0.0048 | 0.0048 | 0.0119 | 0.0193 | 0.0523 | 0.1063 | 0.1010 | 0.1401 | 0.1354 | 0.2415 | 0.0926 | 0.0918 | 0.1330 | 0.1594 | 0.4679 | 0.2367 | 0.0004 | 0.0034 | 0.0068 | 0.0256 | 0.0631 | 0.1062 | 0.0981 | 0.1207 | 0.5755 | 7 | 8 | 9 | 11 | 13 | 22 | 54 | 107 | 186 | 0.1524 | 8.90 | 3.882 | 0.6556 | 13615.0 | 4670000 | 2040000000 | 1060000000000 | 0.5472 | 0.1233 | 0.0212 | 0.0048 | 0.0778 | 0.0100 | 0.2184 | 0.0291 | 0.2431 | 0.0917 | 0.2007 | 0.1943 | 0.1344 | 0.2273 | 0.0654 | 0.1586 | 0.0309 | 0.1369 | 0.0080 | 0.1473 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0018 | 0.0020 | 0.0078 | 0.0083 | 0.0383 | 0.0319 | 0.0619 | 0.0584 | 0.0403 | 0.0398 | 0.0605 | 0.0521 | 0.7895 | 0.8065 | 0.0000 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0038 | 0.0112 | 0.0113 | 0.0443 | 0.0457 | 0.0656 | 0.0707 | 0.0474 | 0.0532 | 0.0740 | 0.0811 | 0.7534 | 0.7324 | 0.0003 | 0.0000 | 0.0021 | 0.0080 | 0.0402 | 0.0651 | 0.0435 | 0.0623 | 0.7784 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1140 | 503 | | 4025 | 13483 | 436.8 | 85.79 | 132.10 | 242.48 | 338 | 368 | 391 | 415 | 440 | 463 | 488 | 513 | 540 | 0.0518 | 698 | 1.105 | 49.03 | 18.38 | 2 | 0.0330 | 133 | 0.0012 | 33.18 | 6.972 | 0.2087 | 198109.0 | 92600000 | 44400000000 | 21800000000000 | 0.4526 | 0.1884 | 0.0007 | 0.0000 | 0.0014 | 0.0000 | 0.0035 | 0.0000 | 0.0139 | 0.0010 | 0.0522 | 0.0198 | 0.1099 | 0.0311 | 0.0967 | 0.0257 | 0.1398 | 0.0363 | 0.5819 | 0.8861 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0037 | 0.0005 | 0.0267 | 0.0189 | 0.0517 | 0.0288 | 0.0402 | 0.0186 | 0.0577 | 0.0283 | 0.8190 | 0.9049 | 0.0050 | 0.0000 | 0.0033 | 0.0606 | 0.0429 | 0.1515 | 0.0759 | 0.2121 | 0.1188 | 0.1212 | 0.1914 | 0.2424 | 0.1452 | 0.1515 | 0.1551 | 0.0303 | 0.2624 | 0.0303 | 0.0005 | 0.0024 | 0.0058 | 0.0169 | 0.0551 | 0.0851 | 0.0807 | 0.1054 | 0.6481 | 6 | 7 | 9 | 10 | 14 | 25 | 74 | 196 | 483 | 0.1545 | 27.57 | 4.157 | 0.6237 | 76242.5 | 60100000 | 54300000000 | 53300000000000 | 0.5764 | 0.1021 | 0.0301 | 0.0017 | 0.1284 | 0.0108 | 0.1997 | 0.0687 | 0.1458 | 0.1026 | 0.1838 | 0.1745 | 0.1331 | 0.1977 | 0.0666 | 0.1266 | 0.0602 | 0.1290 | 0.0523 | 0.1886 | 0.0003 | 0.0000 | 0.0005 | 0.0008 | 0.0025 | 0.0013 | 0.0066 | 0.0078 | 0.0442 | 0.0373 | 0.0700 | 0.0607 | 0.0437 | 0.0396 | 0.0626 | 0.0595 | 0.7696 | 0.7931 | 0.0000 | 0.0014 | 0.0013 | 0.0014 | 0.0027 | 0.0036 | 0.0166 | 0.0159 | 0.0525 | 0.0587 | 0.0807 | 0.0844 | 0.0558 | 0.0543 | 0.0751 | 0.0736 | 0.7153 | 0.7065 | 0.0003 | 0.0012 | 0.0033 | 0.0100 | 0.0504 | 0.0697 | 0.0573 | 0.0733 | 0.7346 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 916 | 208 | | 6312 | 22401 | 516.6 | 108.92 | 194.68 | 249.60 | 387 | 432 | 460 | 485 | 506 | 529 | 554 | 590 | 659 | 0.0487 | 1092 | 1.116 | 137.30 | 45.69 | 1 | 0.0535 | 338 | 0.0007 | 69.42 | 7.543 | 0.1440 | 278766.0 | 157000000 | 92800000000 | 57400000000000 | 0.4428 | 0.2109 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0000 | 0.0104 | 0.0019 | 0.0576 | 0.0179 | 0.1165 | 0.0397 | 0.1247 | 0.0358 | 0.1680 | 0.0608 | 0.5208 | 0.8440 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0054 | 0.0008 | 0.0320 | 0.0120 | 0.0592 | 0.0239 | 0.0665 | 0.0194 | 0.0912 | 0.0340 | 0.7446 | 0.9099 | 0.0077 | 0.0096 | 0.0132 | 0.0096 | 0.0252 | 0.0382 | 0.0614 | 0.0669 | 0.1107 | 0.1369 | 0.1590 | 0.2452 | 0.0998 | 0.1051 | 0.1239 | 0.1624 | 0.3991 | 0.2261 | 0.0021 | 0.0045 | 0.0156 | 0.0403 | 0.0904 | 0.1255 | 0.1172 | 0.1321 | 0.4722 | 8 | 11 | 15 | 29 | 79 | 153 | 245 | 373 | 559 | 0.0687 | 42.39 | 5.505 | 0.4513 | 100197.0 | 70500000 | 59900000000 | 58200000000000 | 0.4609 | 0.1681 | 0.0552 | 0.0013 | 0.1678 | 0.0137 | 0.2533 | 0.1058 | 0.1683 | 0.1355 | 0.1438 | 0.1985 | 0.1037 | 0.1961 | 0.0500 | 0.1334 | 0.0302 | 0.1063 | 0.0276 | 0.1095 | 0.0003 | 0.0001 | 0.0002 | 0.0003 | 0.0016 | 0.0011 | 0.0067 | 0.0064 | 0.0528 | 0.0424 | 0.0871 | 0.0742 | 0.0642 | 0.0559 | 0.0943 | 0.0845 | 0.6926 | 0.7352 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0026 | 0.0047 | 0.0182 | 0.0210 | 0.0633 | 0.0712 | 0.1119 | 0.1303 | 0.0840 | 0.0811 | 0.1128 | 0.1143 | 0.6064 | 0.5764 | 0.0003 | 0.0010 | 0.0028 | 0.0120 | 0.0577 | 0.0977 | 0.0730 | 0.1042 | 0.6513 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 508 | 133 | | 5112 | 15953 | 596.9 | 122.93 | 209.99 | 332.25 | 447 | 490 | 521 | 552 | 585 | 617 | 653 | 698 | 767 | 0.0564 | 899 | 0.855 | 86.15 | 24.76 | 1 | 0.0428 | 219 | 0.0004 | 156.57 | 7.925 | 0.1053 | 371349.0 | 241000000 | 162000000000 | 113000000000000 | 0.4423 | 0.2051 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0187 | 0.0008 | 0.0672 | 0.0192 | 0.1466 | 0.0410 | 0.1398 | 0.0373 | 0.1694 | 0.0551 | 0.4551 | 0.8466 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0089 | 0.0004 | 0.0325 | 0.0132 | 0.0678 | 0.0246 | 0.0610 | 0.0151 | 0.0909 | 0.0305 | 0.7386 | 0.9162 | 0.0023 | 0.0043 | 0.0103 | 0.0043 | 0.0195 | 0.0468 | 0.0736 | 0.1319 | 0.1310 | 0.1872 | 0.2080 | 0.2468 | 0.1023 | 0.0936 | 0.1264 | 0.1106 | 0.3264 | 0.1745 | 0.0008 | 0.0025 | 0.0105 | 0.0257 | 0.0758 | 0.1281 | 0.1049 | 0.1184 | 0.5333 | 8 | 10 | 12 | 14 | 20 | 73 | 208 | 417 | 696 | 0.1770 | 37.47 | 4.561 | 0.5961 | 154477.0 | 156000000 | 189000000000 | 260000000000000 | 0.5567 | 0.1171 | 0.0435 | 0.0017 | 0.1317 | 0.0133 | 0.1719 | 0.0920 | 0.1462 | 0.1123 | 0.1551 | 0.1516 | 0.1272 | 0.1707 | 0.1071 | 0.1244 | 0.0737 | 0.1291 | 0.0435 | 0.2049 | 0.0000 | 0.0003 | 0.0002 | 0.0000 | 0.0013 | 0.0010 | 0.0089 | 0.0045 | 0.0312 | 0.0322 | 0.0618 | 0.0501 | 0.0532 | 0.0353 | 0.0709 | 0.0694 | 0.7724 | 0.8070 | 0.0005 | 0.0002 | 0.0000 | 0.0007 | 0.0023 | 0.0015 | 0.0087 | 0.0100 | 0.0449 | 0.0500 | 0.0795 | 0.0826 | 0.0525 | 0.0585 | 0.0887 | 0.0933 | 0.7230 | 0.7032 | 0.0008 | 0.0015 | 0.0023 | 0.0088 | 0.0390 | 0.0736 | 0.0524 | 0.0793 | 0.7423 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 387 | 777 | | 3566 | 6931 | 639.4 | 107.04 | 10.06 | 4.66 | 486 | 547 | 588 | 620 | 651 | 674 | 700 | 732 | 773 | 0.0884 | 613 | 1.124 | 98.72 | 31.38 | 1 | 0.0670 | 239 | 0.0010 | 36.61 | 7.121 | 0.1989 | 420338.0 | 283000000 | 195000000000 | 137000000000000 | 0.3984 | 0.2382 | 0.0011 | 0.0000 | 0.0011 | 0.0000 | 0.0053 | 0.0000 | 0.0083 | 0.0003 | 0.0320 | 0.0164 | 0.0531 | 0.0288 | 0.0531 | 0.0164 | 0.0753 | 0.0257 | 0.7708 | 0.9124 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0029 | 0.0003 | 0.0186 | 0.0158 | 0.0258 | 0.0270 | 0.0225 | 0.0141 | 0.0287 | 0.0217 | 0.9000 | 0.9211 | 0.0000 | 0.0000 | 0.0149 | 0.1667 | 0.0446 | 0.0833 | 0.0718 | 0.2500 | 0.0767 | 0.2500 | 0.1287 | 0.2500 | 0.0965 | 0.0000 | 0.1658 | 0.0000 | 0.4010 | 0.0000 | 0.0010 | 0.0005 | 0.0021 | 0.0124 | 0.0361 | 0.0465 | 0.0589 | 0.0780 | 0.7646 | 5 | 7 | 7 | 8 | 9 | 10 | 12 | 13 | 16 | 0.4127 | 0.30 | 1.079 | 0.7896 | 122.9 | 1790.87 | 30353.2 | 582290 | 0.5361 | 0.1291 | 0.0335 | 0.0045 | 0.0959 | 0.0139 | 0.1633 | 0.0252 | 0.2000 | 0.0536 | 0.2138 | 0.0902 | 0.1661 | 0.1532 | 0.0951 | 0.2086 | 0.0264 | 0.2648 | 0.0059 | 0.1859 | 0.0097 | 0.0003 | 0.0311 | 0.0027 | 0.0593 | 0.0058 | 0.0757 | 0.0236 | 0.0929 | 0.0587 | 0.1048 | 0.1040 | 0.1018 | 0.1321 | 0.1193 | 0.1860 | 0.4054 | 0.4869 | 0.0652 | 0.0615 | 0.0666 | 0.0608 | 0.0576 | 0.0615 | 0.0566 | 0.0660 | 0.0756 | 0.0801 | 0.0809 | 0.1008 | 0.0856 | 0.1127 | 0.1365 | 0.1579 | 0.3754 | 0.2987 | 0.0501 | 0.0714 | 0.0772 | 0.0740 | 0.0778 | 0.0730 | 0.0804 | 0.1126 | 0.3836 | ||
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 290 | 183 | | 4256 | 13621 | 278.3 | 66.28 | 52.14 | 89.83 | 200 | 217 | 234 | 252 | 270 | 288 | 309 | 335 | 371 | 0.0612 | 833 | 0.939 | 141.41 | 38.83 | 1 | 0.0834 | 355 | 0.0016 | 23.89 | 6.657 | 0.2270 | 81857.7 | 25400000 | 8320000000 | 2860000000000 | 0.4253 | 0.2138 | 0.0008 | 0.0000 | 0.0025 | 0.0000 | 0.0074 | 0.0005 | 0.0252 | 0.0015 | 0.0724 | 0.0233 | 0.1410 | 0.0432 | 0.1398 | 0.0399 | 0.1538 | 0.0598 | 0.4570 | 0.8318 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0021 | 0.0002 | 0.0097 | 0.0005 | 0.0314 | 0.0158 | 0.0557 | 0.0227 | 0.0588 | 0.0161 | 0.0679 | 0.0250 | 0.7738 | 0.9197 | 0.0035 | 0.0040 | 0.0046 | 0.0316 | 0.0139 | 0.0316 | 0.0600 | 0.1107 | 0.0970 | 0.1304 | 0.1420 | 0.2530 | 0.1328 | 0.1265 | 0.1582 | 0.1265 | 0.3880 | 0.1858 | 0.0000 | 0.0026 | 0.0072 | 0.0231 | 0.0610 | 0.0882 | 0.0897 | 0.1138 | 0.6144 | 9 | 12 | 15 | 19 | 25 | 33 | 46 | 64 | 104 | 0.0785 | 5.90 | 3.743 | 0.6772 | 10786.6 | 5170000 | 3390000000 | 2570000000000 | 0.6243 | 0.0753 | 0.0181 | 0.0077 | 0.0561 | 0.0176 | 0.1074 | 0.0366 | 0.1767 | 0.0628 | 0.1659 | 0.1173 | 0.1671 | 0.1313 | 0.1586 | 0.1494 | 0.1031 | 0.1736 | 0.0470 | 0.3037 | 0.0025 | 0.0042 | 0.0049 | 0.0065 | 0.0096 | 0.0102 | 0.0257 | 0.0169 | 0.0558 | 0.0506 | 0.0842 | 0.0709 | 0.0788 | 0.0603 | 0.1058 | 0.0884 | 0.6327 | 0.6919 | 0.0021 | 0.0030 | 0.0071 | 0.0061 | 0.0163 | 0.0177 | 0.0351 | 0.0402 | 0.0844 | 0.0987 | 0.1163 | 0.1043 | 0.0879 | 0.0948 | 0.1180 | 0.1168 | 0.5328 | 0.5184 | 0.0025 | 0.0044 | 0.0119 | 0.0266 | 0.0716 | 0.1041 | 0.0858 | 0.1224 | 0.5706 |