High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 439 | | 9462 | 17615 | 66.2 | 18.80 | 11.63 | 7.94 | 45 | 48 | 51 | 57 | 63 | 69 | 76 | 85 | 93 | 0.0582 | 1025 | 0.806 | 93.06 | 26.68 | 0 | 0.0260 | 246 | 0.0396 | 0.80 | 3.627 | 0.7208 | 4738.0 | 364637 | 29900000 | 2590000000 | 0.4090 | 0.2322 | 0.0114 | 0.0009 | 0.0137 | 0.0014 | 0.0190 | 0.0032 | 0.0307 | 0.0089 | 0.0497 | 0.0193 | 0.0678 | 0.0417 | 0.0898 | 0.0415 | 0.1269 | 0.0742 | 0.5909 | 0.8088 | 0.0052 | 0.0000 | 0.0064 | 0.0002 | 0.0081 | 0.0003 | 0.0109 | 0.0024 | 0.0165 | 0.0081 | 0.0215 | 0.0205 | 0.0284 | 0.0132 | 0.0370 | 0.0319 | 0.8659 | 0.9234 | 0.0061 | 0.0140 | 0.0065 | 0.0220 | 0.0105 | 0.0451 | 0.0252 | 0.0762 | 0.0304 | 0.1062 | 0.0527 | 0.1333 | 0.0641 | 0.1283 | 0.0933 | 0.1413 | 0.7112 | 0.3337 | 0.0026 | 0.0049 | 0.0086 | 0.0123 | 0.0283 | 0.0339 | 0.0416 | 0.0706 | 0.7972 | 5 | 6 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 0.2867 | 0.33 | 1.922 | 0.8442 | 198.3 | 4862.52 | 154893 | 5820000 | 0.5138 | 0.1400 | 0.0871 | 0.0128 | 0.1401 | 0.0280 | 0.1505 | 0.0586 | 0.1491 | 0.0912 | 0.1521 | 0.1375 | 0.1294 | 0.1665 | 0.1167 | 0.1770 | 0.0606 | 0.1781 | 0.0146 | 0.1503 | 0.0408 | 0.0059 | 0.0668 | 0.0174 | 0.0671 | 0.0381 | 0.0575 | 0.0614 | 0.0582 | 0.0937 | 0.0540 | 0.1156 | 0.0645 | 0.1142 | 0.0925 | 0.1136 | 0.4986 | 0.4402 | 0.0246 | 0.0157 | 0.0222 | 0.0242 | 0.0309 | 0.0310 | 0.0415 | 0.0336 | 0.0492 | 0.0529 | 0.0632 | 0.0663 | 0.0719 | 0.0777 | 0.1169 | 0.1326 | 0.5796 | 0.5660 | 0.0564 | 0.0389 | 0.0353 | 0.0306 | 0.0484 | 0.0603 | 0.0728 | 0.0984 | 0.5589 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 488 | | 1658 | 7515 | 661.2 | 127.45 | 21.12 | 72.35 | 472 | 534 | 588 | 636 | 672 | 708 | 749 | 791 | 831 | 0.0896 | 673 | 1.056 | 79.26 | 20.40 | 1 | 0.1128 | 187 | 0.0037 | 8.63 | 5.897 | 0.3770 | 453371.0 | 321000000 | 233000000000 | 172000000000000 | 0.3992 | 0.2328 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0029 | 0.0000 | 0.0098 | 0.0018 | 0.0479 | 0.0231 | 0.0685 | 0.0358 | 0.0607 | 0.0219 | 0.0881 | 0.0328 | 0.7202 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0018 | 0.0283 | 0.0231 | 0.0358 | 0.0358 | 0.0253 | 0.0219 | 0.0365 | 0.0328 | 0.8718 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0000 | 0.0344 | 0.0000 | 0.0531 | 0.0000 | 0.0531 | 0.0000 | 0.0688 | 0.0000 | 0.1000 | 0.0000 | 0.6781 | 0.0000 | 0.0011 | 0.0011 | 0.0034 | 0.0135 | 0.0270 | 0.0529 | 0.0450 | 0.0541 | 0.8018 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 12 | 17 | 0.1063 | 2.38 | 1.499 | 0.4250 | 5680.0 | 3330000 | 2380000000 | 1890000000000 | 0.4909 | 0.1207 | 0.0780 | 0.0610 | 0.2110 | 0.0749 | 0.2844 | 0.0999 | 0.2661 | 0.1207 | 0.0826 | 0.1914 | 0.0505 | 0.1692 | 0.0092 | 0.0874 | 0.0138 | 0.0707 | 0.0046 | 0.1248 | 0.0181 | 0.0352 | 0.0233 | 0.0424 | 0.0194 | 0.0488 | 0.0440 | 0.0456 | 0.0660 | 0.0697 | 0.0699 | 0.0689 | 0.0621 | 0.0817 | 0.0776 | 0.0961 | 0.6197 | 0.5116 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0054 | 0.0000 | 0.0090 | 0.0189 | 0.0667 | 0.0682 | 0.1189 | 0.0928 | 0.0360 | 0.0625 | 0.0811 | 0.0795 | 0.6829 | 0.6761 | 0.0016 | 0.0064 | 0.0096 | 0.0305 | 0.0595 | 0.0691 | 0.0740 | 0.0804 | 0.6688 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 919 | 347 | | 5602 | 6122 | 469.4 | 79.21 | 27.49 | 47.62 | 357 | 396 | 427 | 455 | 479 | 496 | 513 | 531 | 559 | 0.1042 | 638 | 0.998 | 133.18 | 37.86 | 1 | 0.0605 | 339 | 0.0017 | 16.11 | 6.642 | 0.3084 | 226643.0 | 112000000 | 57000000000 | 29500000000000 | 0.4201 | 0.2305 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0000 | 0.0068 | 0.0007 | 0.0224 | 0.0104 | 0.0352 | 0.0294 | 0.0373 | 0.0137 | 0.0623 | 0.0225 | 0.8308 | 0.9233 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0025 | 0.0000 | 0.0042 | 0.0005 | 0.0136 | 0.0097 | 0.0247 | 0.0272 | 0.0207 | 0.0098 | 0.0262 | 0.0177 | 0.9067 | 0.9351 | 0.0187 | 0.0000 | 0.0093 | 0.0541 | 0.0093 | 0.0811 | 0.0318 | 0.1622 | 0.0486 | 0.1892 | 0.0542 | 0.1892 | 0.0710 | 0.0811 | 0.0841 | 0.1351 | 0.6729 | 0.1081 | 0.0000 | 0.0020 | 0.0049 | 0.0120 | 0.0273 | 0.0462 | 0.0524 | 0.0908 | 0.7645 | 8 | 10 | 12 | 14 | 15 | 17 | 20 | 29 | 50 | 0.3237 | 1.45 | 2.056 | 0.8309 | 3023.4 | 1020000 | 532000000 | 337000000000 | 0.5358 | 0.1270 | 0.0965 | 0.0392 | 0.0856 | 0.0530 | 0.0911 | 0.0723 | 0.1111 | 0.0933 | 0.1840 | 0.1154 | 0.1858 | 0.1198 | 0.1056 | 0.1375 | 0.1093 | 0.1452 | 0.0310 | 0.2242 | 0.0300 | 0.0239 | 0.0257 | 0.0316 | 0.0178 | 0.0421 | 0.0165 | 0.0541 | 0.0484 | 0.0733 | 0.0772 | 0.0824 | 0.0502 | 0.0798 | 0.0876 | 0.0900 | 0.6467 | 0.5229 | 0.0018 | 0.0011 | 0.0092 | 0.0063 | 0.0111 | 0.0138 | 0.0129 | 0.0180 | 0.0563 | 0.0624 | 0.0969 | 0.0963 | 0.0572 | 0.0709 | 0.0895 | 0.1270 | 0.6651 | 0.6042 | 0.0092 | 0.0077 | 0.0061 | 0.0146 | 0.0452 | 0.0958 | 0.0598 | 0.0782 | 0.6835 | ||
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1161 | 623 | | 4896 | 12890 | 292.1 | 122.93 | 77.58 | 156.83 | 140 | 170 | 195 | 234 | 275 | 322 | 378 | 426 | 471 | 0.0714 | 920 | 0.771 | 63.56 | 16.03 | 4 | 0.0327 | 160 | 0.0010 | 16.01 | 7.132 | 0.2695 | 100453.0 | 38700000 | 16000000000 | 6940000000000 | 0.3486 | 0.2680 | 0.0008 | 0.0004 | 0.0008 | 0.0015 | 0.0008 | 0.0030 | 0.0194 | 0.0109 | 0.0891 | 0.0449 | 0.1336 | 0.0612 | 0.1263 | 0.0581 | 0.1571 | 0.0849 | 0.4721 | 0.7350 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0003 | 0.0018 | 0.0061 | 0.0047 | 0.0187 | 0.0171 | 0.0224 | 0.0237 | 0.0252 | 0.0179 | 0.0330 | 0.0339 | 0.8936 | 0.9006 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0035 | 0.0053 | 0.0087 | 0.0381 | 0.0582 | 0.0545 | 0.0582 | 0.0393 | 0.0616 | 0.0527 | 0.0851 | 0.8102 | 0.7240 | 0.0000 | 0.0004 | 0.0009 | 0.0035 | 0.0274 | 0.0363 | 0.0314 | 0.0456 | 0.8544 | 7 | 9 | 11 | 13 | 17 | 25 | 42 | 84 | 223 | 0.1061 | 17.09 | 3.929 | 0.6640 | 30613.2 | 21000000 | 18400000000 | 18500000000000 | 0.3956 | 0.2278 | 0.0335 | 0.0066 | 0.0911 | 0.0183 | 0.1580 | 0.0374 | 0.2026 | 0.0682 | 0.2286 | 0.1364 | 0.1283 | 0.1540 | 0.1022 | 0.1393 | 0.0353 | 0.1598 | 0.0204 | 0.2801 | 0.0027 | 0.0025 | 0.0047 | 0.0030 | 0.0047 | 0.0050 | 0.0097 | 0.0116 | 0.0484 | 0.0449 | 0.0684 | 0.0581 | 0.0494 | 0.0512 | 0.0735 | 0.0722 | 0.7386 | 0.7516 | 0.0004 | 0.0009 | 0.0004 | 0.0004 | 0.0033 | 0.0035 | 0.0114 | 0.0097 | 0.0521 | 0.0578 | 0.0720 | 0.0843 | 0.0606 | 0.0618 | 0.0781 | 0.0856 | 0.7216 | 0.6961 | 0.0004 | 0.0011 | 0.0026 | 0.0086 | 0.0474 | 0.0784 | 0.0523 | 0.0732 | 0.7359 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 591 | 322 | | 3805 | 8120 | 447.6 | 140.46 | 62.41 | 102.20 | 225 | 309 | 397 | 453 | 481 | 505 | 531 | 568 | 598 | 0.0792 | 643 | 1.179 | 95.75 | 35.78 | 2 | 0.0636 | 242 | 0.0012 | 24.22 | 7.023 | 0.2589 | 220069.0 | 114000000 | 61800000000 | 34400000000000 | 0.3868 | 0.2449 | 0.0017 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0114 | 0.0030 | 0.0542 | 0.0207 | 0.0787 | 0.0353 | 0.0685 | 0.0267 | 0.1038 | 0.0443 | 0.6805 | 0.8697 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0019 | 0.0183 | 0.0158 | 0.0254 | 0.0260 | 0.0183 | 0.0167 | 0.0268 | 0.0236 | 0.9097 | 0.9160 | 0.0009 | 0.0000 | 0.0037 | 0.0000 | 0.0083 | 0.0000 | 0.0111 | 0.0000 | 0.0426 | 0.0000 | 0.0546 | 0.0000 | 0.0592 | 0.0000 | 0.0823 | 0.0000 | 0.7373 | 1.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0047 | 0.0236 | 0.0356 | 0.0347 | 0.0592 | 0.8404 | 8 | 9 | 11 | 12 | 16 | 24 | 45 | 91 | 190 | 0.1789 | 5.12 | 3.242 | 0.6875 | 14337.8 | 5250000 | 2370000000 | 1220000000000 | 0.6067 | 0.0913 | 0.0581 | 0.0060 | 0.1183 | 0.0249 | 0.1618 | 0.0957 | 0.1390 | 0.1256 | 0.1784 | 0.1446 | 0.1515 | 0.1605 | 0.1224 | 0.1296 | 0.0456 | 0.0987 | 0.0249 | 0.2144 | 0.0017 | 0.0015 | 0.0035 | 0.0026 | 0.0035 | 0.0045 | 0.0138 | 0.0146 | 0.0558 | 0.0544 | 0.0878 | 0.0773 | 0.0636 | 0.0484 | 0.0930 | 0.0926 | 0.6775 | 0.7041 | 0.0005 | 0.0006 | 0.0005 | 0.0006 | 0.0033 | 0.0024 | 0.0169 | 0.0192 | 0.0754 | 0.0800 | 0.1038 | 0.1191 | 0.0644 | 0.0565 | 0.1032 | 0.1179 | 0.6319 | 0.6037 | 0.0010 | 0.0034 | 0.0039 | 0.0186 | 0.0658 | 0.0932 | 0.0677 | 0.0991 | 0.6472 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 956 | 481 | | 1986 | 9878 | 45.3 | 11.48 | 35.21 | 55.46 | 30 | 34 | 39 | 42 | 45 | 48 | 51 | 56 | 60 | 0.0765 | 756 | 0.806 | 36.77 | 10.44 | 2 | 0.0539 | 107 | 0.0083 | 3.62 | 5.056 | 0.4649 | 2186.4 | 111365 | 5950000 | 331000000 | 0.4003 | 0.2238 | 0.0019 | 0.0000 | 0.0028 | 0.0011 | 0.0131 | 0.0045 | 0.0327 | 0.0129 | 0.0515 | 0.0286 | 0.0776 | 0.0432 | 0.1132 | 0.0510 | 0.1506 | 0.0875 | 0.5566 | 0.7712 | 0.0006 | 0.0000 | 0.0006 | 0.0000 | 0.0039 | 0.0021 | 0.0129 | 0.0078 | 0.0207 | 0.0204 | 0.0311 | 0.0266 | 0.0317 | 0.0282 | 0.0498 | 0.0408 | 0.8485 | 0.8741 | 0.0084 | 0.0229 | 0.0231 | 0.0458 | 0.0231 | 0.1069 | 0.0273 | 0.0992 | 0.0588 | 0.0840 | 0.0546 | 0.0992 | 0.0777 | 0.1603 | 0.1387 | 0.1221 | 0.5882 | 0.2595 | 0.0019 | 0.0058 | 0.0145 | 0.0270 | 0.0462 | 0.0568 | 0.0751 | 0.0934 | 0.6792 | 12 | 14 | 15 | 16 | 18 | 22 | 28 | 39 | 66 | 0.3765 | 2.00 | 2.023 | 0.8544 | 4314.9 | 1380000 | 642000000 | 351000000000 | 0.5769 | 0.1123 | 0.0338 | 0.0176 | 0.0938 | 0.0290 | 0.1429 | 0.0522 | 0.1420 | 0.0746 | 0.1488 | 0.1228 | 0.1505 | 0.1485 | 0.1234 | 0.1246 | 0.1023 | 0.1456 | 0.0626 | 0.2849 | 0.0033 | 0.0112 | 0.0063 | 0.0160 | 0.0139 | 0.0227 | 0.0325 | 0.0284 | 0.0634 | 0.0516 | 0.0933 | 0.0672 | 0.0863 | 0.0700 | 0.1218 | 0.1011 | 0.5792 | 0.6317 | 0.0016 | 0.0048 | 0.0055 | 0.0068 | 0.0131 | 0.0109 | 0.0344 | 0.0505 | 0.1071 | 0.1038 | 0.1301 | 0.1633 | 0.0945 | 0.1004 | 0.1519 | 0.1346 | 0.4617 | 0.4249 | 0.0047 | 0.0060 | 0.0125 | 0.0324 | 0.0824 | 0.1100 | 0.0846 | 0.1342 | 0.5332 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 703 | 330 | | 1517 | 7267 | 260.9 | 69.91 | 59.78 | 117.99 | 178 | 191 | 206 | 227 | 248 | 274 | 304 | 331 | 369 | 0.0860 | 625 | 1.115 | 107.79 | 38.05 | 1 | 0.1793 | 272 | 0.0105 | 1.72 | 4.763 | 0.5649 | 72953.0 | 21700000 | 6830000000 | 2240000000000 | 0.3508 | 0.2996 | 0.0016 | 0.0000 | 0.0031 | 0.0000 | 0.0062 | 0.0015 | 0.0171 | 0.0067 | 0.0715 | 0.0340 | 0.0964 | 0.0503 | 0.1026 | 0.0392 | 0.1291 | 0.0673 | 0.5723 | 0.8010 | 0.0010 | 0.0000 | 0.0019 | 0.0000 | 0.0019 | 0.0000 | 0.0057 | 0.0040 | 0.0306 | 0.0224 | 0.0373 | 0.0369 | 0.0335 | 0.0257 | 0.0450 | 0.0383 | 0.8431 | 0.8727 | 0.0025 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0061 | 0.0124 | 0.0549 | 0.0423 | 0.0610 | 0.0547 | 0.0549 | 0.0448 | 0.1220 | 0.0821 | 0.0854 | 0.7512 | 0.6159 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0337 | 0.0527 | 0.0366 | 0.0439 | 0.8228 | 7 | 8 | 9 | 10 | 11 | 15 | 28 | 57 | 188 | 0.1752 | 2.71 | 2.781 | 0.6871 | 17493.2 | 7830000 | 4090000000 | 2340000000000 | 0.4255 | 0.2007 | 0.0273 | 0.0043 | 0.0648 | 0.0086 | 0.1297 | 0.0114 | 0.2150 | 0.0643 | 0.2116 | 0.1186 | 0.1502 | 0.1686 | 0.1229 | 0.1429 | 0.0614 | 0.1629 | 0.0171 | 0.3186 | 0.0031 | 0.0010 | 0.0037 | 0.0021 | 0.0074 | 0.0026 | 0.0155 | 0.0129 | 0.0372 | 0.0290 | 0.0440 | 0.0403 | 0.0415 | 0.0445 | 0.0551 | 0.0672 | 0.7926 | 0.8004 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0023 | 0.0024 | 0.0053 | 0.0097 | 0.0371 | 0.0308 | 0.0393 | 0.0559 | 0.0446 | 0.0454 | 0.0598 | 0.0608 | 0.8086 | 0.7950 | 0.0000 | 0.0021 | 0.0049 | 0.0119 | 0.0295 | 0.0372 | 0.0400 | 0.0534 | 0.8209 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 214 | 329 | | 2935 | 11303 | 279.9 | 61.40 | 6.40 | 2.56 | 193 | 217 | 240 | 262 | 283 | 300 | 320 | 339 | 363 | 0.0572 | 646 | 0.707 | 220.60 | 68.41 | 1 | 0.2290 | 672 | 0.0038 | 5.82 | 5.792 | 0.3874 | 82100.6 | 25100000 | 7920000000 | 2580000000000 | 0.3742 | 0.2640 | 0.0012 | 0.0000 | 0.0055 | 0.0000 | 0.0068 | 0.0003 | 0.0197 | 0.0035 | 0.0419 | 0.0219 | 0.0653 | 0.0299 | 0.0635 | 0.0285 | 0.1054 | 0.0597 | 0.6907 | 0.8563 | 0.0009 | 0.0000 | 0.0018 | 0.0000 | 0.0013 | 0.0003 | 0.0075 | 0.0027 | 0.0168 | 0.0196 | 0.0266 | 0.0240 | 0.0239 | 0.0192 | 0.0350 | 0.0343 | 0.8862 | 0.8998 | 0.0031 | 0.1875 | 0.0126 | 0.2813 | 0.0173 | 0.3750 | 0.0346 | 0.0938 | 0.0456 | 0.0625 | 0.0566 | 0.0000 | 0.0629 | 0.0000 | 0.0849 | 0.0000 | 0.6824 | 0.0000 | 0.0013 | 0.0020 | 0.0059 | 0.0092 | 0.0277 | 0.0323 | 0.0323 | 0.0554 | 0.8339 | 3 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 10 | 0.4396 | 0.38 | 1.169 | 0.8081 | 47.5 | 391.249 | 3512.14 | 33881.8 | 0.4867 | 0.1660 | 0.0087 | 0.0004 | 0.0533 | 0.0075 | 0.1339 | 0.0348 | 0.2382 | 0.1039 | 0.2579 | 0.1830 | 0.1883 | 0.2424 | 0.0921 | 0.2426 | 0.0230 | 0.1419 | 0.0046 | 0.0434 | 0.0002 | 0.0000 | 0.0018 | 0.0009 | 0.0097 | 0.0035 | 0.0393 | 0.0162 | 0.0799 | 0.0427 | 0.1426 | 0.0876 | 0.2155 | 0.1902 | 0.2757 | 0.3292 | 0.2352 | 0.3297 | 0.0810 | 0.1861 | 0.1648 | 0.2753 | 0.2049 | 0.2537 | 0.1900 | 0.1433 | 0.1511 | 0.0792 | 0.1073 | 0.0385 | 0.0628 | 0.0186 | 0.0300 | 0.0043 | 0.0081 | 0.0009 | 0.0035 | 0.0243 | 0.0659 | 0.1244 | 0.1728 | 0.2058 | 0.2030 | 0.1370 | 0.0633 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 328 | 685 | | 3310 | 17319 | 115.5 | 44.52 | 5.43 | 1.99 | 62 | 70 | 80 | 93 | 109 | 124 | 140 | 161 | 181 | 0.0577 | 999 | 0.991 | 31.40 | 10.77 | 2 | 0.0266 | 88 | 0.0050 | 4.21 | 5.619 | 0.4414 | 15310.3 | 2260000 | 362000000 | 61100000000 | 0.3498 | 0.2779 | 0.0021 | 0.0010 | 0.0072 | 0.0039 | 0.0123 | 0.0093 | 0.0349 | 0.0181 | 0.0739 | 0.0366 | 0.1242 | 0.0439 | 0.1232 | 0.0649 | 0.1828 | 0.0825 | 0.4394 | 0.7399 | 0.0005 | 0.0007 | 0.0015 | 0.0026 | 0.0035 | 0.0048 | 0.0089 | 0.0096 | 0.0212 | 0.0177 | 0.0227 | 0.0184 | 0.0257 | 0.0302 | 0.0420 | 0.0350 | 0.8741 | 0.8809 | 0.0010 | 0.0000 | 0.0019 | 0.0045 | 0.0086 | 0.0106 | 0.0209 | 0.0151 | 0.0409 | 0.0452 | 0.0571 | 0.0603 | 0.0523 | 0.0724 | 0.0647 | 0.0799 | 0.7526 | 0.7119 | 0.0013 | 0.0000 | 0.0013 | 0.0097 | 0.0232 | 0.0387 | 0.0290 | 0.0574 | 0.8395 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.2714 | 0.47 | 1.049 | 0.6358 | 33.5 | 227.156 | 1669.44 | 13153.9 | 0.4485 | 0.2089 | 0.0313 | 0.0023 | 0.0940 | 0.0125 | 0.1602 | 0.0406 | 0.2077 | 0.0829 | 0.2080 | 0.1416 | 0.1737 | 0.2164 | 0.0888 | 0.2463 | 0.0321 | 0.1826 | 0.0043 | 0.0747 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0030 | 0.0008 | 0.0099 | 0.0050 | 0.0301 | 0.0153 | 0.0780 | 0.0258 | 0.2017 | 0.0630 | 0.3485 | 0.2345 | 0.3287 | 0.6554 | 0.0177 | 0.0768 | 0.0775 | 0.1643 | 0.1302 | 0.2136 | 0.1742 | 0.2130 | 0.1942 | 0.1573 | 0.1860 | 0.0951 | 0.1327 | 0.0548 | 0.0683 | 0.0195 | 0.0192 | 0.0057 | 0.0007 | 0.0109 | 0.0459 | 0.1123 | 0.1876 | 0.2387 | 0.2118 | 0.1393 | 0.0528 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 705 | 656 | | 2086 | 7084 | 755.3 | 409.67 | 4.68 | 2.47 | 169 | 264 | 426 | 649 | 862 | 982 | 1060 | 1141 | 1240 | 0.0841 | 596 | 0.902 | 85.38 | 22.85 | 2 | 0.1112 | 232 | 0.0008 | 88.53 | 7.287 | 0.1150 | 738249.0 | 798000000 | 907000000000 | 1.07E+15 | 0.3090 | 0.2823 | 0.0000 | 0.0000 | 0.0167 | 0.0013 | 0.0167 | 0.0013 | 0.0733 | 0.0088 | 0.3067 | 0.1107 | 0.2867 | 0.1723 | 0.1300 | 0.1233 | 0.1300 | 0.1849 | 0.0400 | 0.3975 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0264 | 0.0280 | 0.0380 | 0.0350 | 0.0233 | 0.0224 | 0.0396 | 0.0378 | 0.8712 | 0.8768 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0016 | 0.0030 | 0.0174 | 0.0324 | 0.0757 | 0.0576 | 0.1372 | 0.0536 | 0.0931 | 0.0890 | 0.1483 | 0.7634 | 0.5268 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0328 | 0.0345 | 0.0276 | 0.0405 | 0.8638 | 2 | 3 | 3 | 4 | 4 | 5 | 6 | 7 | 8 | 0.0353 | 0.22 | 0.723 | 0.2177 | 28.0 | 197.373 | 1573.42 | 13861.8 | 0.4480 | 0.1854 | 0.0919 | 0.0083 | 0.1989 | 0.0206 | 0.2527 | 0.0511 | 0.2301 | 0.0975 | 0.1382 | 0.1832 | 0.0656 | 0.2464 | 0.0204 | 0.2343 | 0.0022 | 0.1254 | 0.0000 | 0.0331 | 0.0082 | 0.0009 | 0.0316 | 0.0026 | 0.0687 | 0.0139 | 0.0919 | 0.0357 | 0.1178 | 0.0764 | 0.1357 | 0.1283 | 0.1428 | 0.1664 | 0.1753 | 0.2158 | 0.2280 | 0.3601 | 0.0631 | 0.0852 | 0.0954 | 0.1085 | 0.0927 | 0.1085 | 0.0907 | 0.1143 | 0.1286 | 0.1214 | 0.1226 | 0.1375 | 0.1302 | 0.1336 | 0.1434 | 0.0943 | 0.1334 | 0.0968 | 0.0278 | 0.0633 | 0.1001 | 0.0986 | 0.1143 | 0.1134 | 0.1331 | 0.1597 | 0.1898 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 555 | 532 | | 3465 | 14759 | 319.8 | 107.54 | 6.73 | 2.27 | 198 | 221 | 243 | 273 | 310 | 350 | 374 | 394 | 435 | 0.0700 | 1033 | 1.221 | 77.39 | 27.66 | 2 | 0.0543 | 188 | 0.0057 | 5.18 | 5.576 | 0.4523 | 113808.0 | 45100000 | 19800000000 | 9650000000000 | 0.4430 | 0.1901 | 0.0028 | 0.0000 | 0.0063 | 0.0000 | 0.0042 | 0.0017 | 0.0245 | 0.0068 | 0.0756 | 0.0345 | 0.1436 | 0.0519 | 0.1289 | 0.0420 | 0.1646 | 0.0615 | 0.4496 | 0.8016 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0004 | 0.0012 | 0.0105 | 0.0031 | 0.0285 | 0.0271 | 0.0558 | 0.0389 | 0.0378 | 0.0249 | 0.0470 | 0.0408 | 0.8187 | 0.8639 | 0.0106 | 0.0000 | 0.0153 | 0.0071 | 0.0188 | 0.0035 | 0.0259 | 0.0390 | 0.0506 | 0.0887 | 0.0576 | 0.0957 | 0.0682 | 0.0780 | 0.0988 | 0.0993 | 0.6541 | 0.5887 | 0.0000 | 0.0024 | 0.0018 | 0.0152 | 0.0328 | 0.0425 | 0.0334 | 0.0468 | 0.8251 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0844 | 0.35 | 0.898 | 0.3300 | 50.5 | 413.246 | 3661.4 | 35082.4 | 0.5392 | 0.1292 | 0.0068 | 0.0003 | 0.0451 | 0.0042 | 0.1067 | 0.0171 | 0.1894 | 0.0476 | 0.2341 | 0.0957 | 0.2205 | 0.1698 | 0.1356 | 0.2507 | 0.0525 | 0.2678 | 0.0093 | 0.1466 | 0.0014 | 0.0002 | 0.0128 | 0.0021 | 0.0344 | 0.0077 | 0.0739 | 0.0219 | 0.1043 | 0.0520 | 0.1474 | 0.0981 | 0.1623 | 0.1436 | 0.2138 | 0.2421 | 0.2497 | 0.4324 | 0.1133 | 0.1976 | 0.1372 | 0.2142 | 0.1664 | 0.1783 | 0.1654 | 0.1636 | 0.1518 | 0.1123 | 0.1186 | 0.0744 | 0.0801 | 0.0372 | 0.0458 | 0.0160 | 0.0213 | 0.0064 | 0.0167 | 0.0531 | 0.0922 | 0.1109 | 0.1310 | 0.1500 | 0.1506 | 0.1588 | 0.1366 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 308 | 884 | | 5050 | 10182 | 749.7 | 126.97 | 42.65 | 71.54 | 594 | 652 | 686 | 713 | 737 | 762 | 805 | 871 | 942 | 0.0693 | 706 | 1.198 | 99.81 | 37.54 | 1 | 0.0493 | 249 | 0.0009 | 44.07 | 7.331 | 0.2040 | 578151.0 | 458000000 | 371000000000 | 308000000000000 | 0.4226 | 0.2196 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0068 | 0.0006 | 0.0285 | 0.0120 | 0.0415 | 0.0212 | 0.0388 | 0.0132 | 0.0616 | 0.0186 | 0.8190 | 0.9345 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0020 | 0.0006 | 0.0159 | 0.0120 | 0.0237 | 0.0212 | 0.0190 | 0.0116 | 0.0326 | 0.0178 | 0.9061 | 0.9369 | 0.0036 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0169 | 1.0000 | 0.0495 | 0.0000 | 0.0579 | 0.0000 | 0.0760 | 0.0000 | 0.0893 | 0.0000 | 0.7045 | 0.0000 | 0.0027 | 0.0054 | 0.0125 | 0.0152 | 0.0411 | 0.0438 | 0.0585 | 0.0688 | 0.7520 | 6 | 8 | 9 | 11 | 13 | 19 | 36 | 60 | 109 | 0.1640 | 2.95 | 2.935 | 0.7102 | 6935.9 | 2170000 | 941000000 | 501000000000 | 0.4404 | 0.1899 | 0.0194 | 0.0075 | 0.0535 | 0.0125 | 0.1069 | 0.0337 | 0.1470 | 0.0580 | 0.1701 | 0.1079 | 0.1750 | 0.1341 | 0.1665 | 0.1248 | 0.1130 | 0.1622 | 0.0486 | 0.3593 | 0.0013 | 0.0014 | 0.0041 | 0.0022 | 0.0048 | 0.0064 | 0.0153 | 0.0160 | 0.0396 | 0.0329 | 0.0616 | 0.0440 | 0.0517 | 0.0442 | 0.0727 | 0.0650 | 0.7490 | 0.7879 | 0.0017 | 0.0020 | 0.0043 | 0.0035 | 0.0108 | 0.0055 | 0.0208 | 0.0179 | 0.0554 | 0.0546 | 0.0705 | 0.0789 | 0.0575 | 0.0645 | 0.0809 | 0.0904 | 0.6981 | 0.6827 | 0.0015 | 0.0037 | 0.0104 | 0.0186 | 0.0443 | 0.0707 | 0.0592 | 0.0878 | 0.7039 | ||
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 602 | 376 | | 1156 | 4064 | 474.2 | 143.37 | 10.35 | 8.30 | 315 | 334 | 360 | 391 | 431 | 490 | 562 | 644 | 697 | 0.0947 | 385 | 1.114 | 51.86 | 18.44 | 1 | 0.1211 | 140 | 0.0033 | 11.41 | 6.019 | 0.2906 | 245360.0 | 137000000 | 81700000000 | 51000000000000 | 0.3632 | 0.2648 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0025 | 0.0010 | 0.0327 | 0.0031 | 0.0955 | 0.0462 | 0.1382 | 0.0776 | 0.1709 | 0.0525 | 0.1608 | 0.0860 | 0.3995 | 0.7324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0009 | 0.0136 | 0.0017 | 0.0339 | 0.0304 | 0.0434 | 0.0470 | 0.0542 | 0.0261 | 0.0488 | 0.0487 | 0.8049 | 0.8452 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0118 | 0.0152 | 0.0559 | 0.0812 | 0.0588 | 0.0812 | 0.0559 | 0.0558 | 0.0765 | 0.1269 | 0.7412 | 0.6396 | 0.0000 | 0.0000 | 0.0000 | 0.0041 | 0.0412 | 0.0741 | 0.0329 | 0.0658 | 0.7819 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 15 | 0.0098 | 16.68 | 5.103 | 0.3379 | 176.1 | 6409.85 | 409709 | 33400000 | 0.4040 | 0.2136 | 0.0440 | 0.0038 | 0.1040 | 0.0105 | 0.1253 | 0.0332 | 0.2015 | 0.0514 | 0.2154 | 0.0867 | 0.1685 | 0.1160 | 0.1026 | 0.1499 | 0.0330 | 0.2376 | 0.0059 | 0.3110 | 0.0174 | 0.0014 | 0.0349 | 0.0052 | 0.0418 | 0.0193 | 0.0499 | 0.0293 | 0.0774 | 0.0503 | 0.1078 | 0.0748 | 0.1139 | 0.0871 | 0.1390 | 0.1550 | 0.4179 | 0.5775 | 0.0490 | 0.0472 | 0.0672 | 0.0407 | 0.0608 | 0.0650 | 0.0572 | 0.0911 | 0.0762 | 0.1382 | 0.1016 | 0.1154 | 0.1143 | 0.1073 | 0.1661 | 0.1268 | 0.3076 | 0.2683 | 0.0357 | 0.0421 | 0.0562 | 0.0761 | 0.0860 | 0.1094 | 0.1018 | 0.1281 | 0.3645 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 632 | 365 | | 4889 | 13256 | 383.0 | 256.14 | 34.30 | 57.66 | 183 | 197 | 211 | 228 | 257 | 316 | 420 | 590 | 842 | 0.0671 | 890 | 0.504 | 95.59 | 26.87 | 10 | 0.0714 | 349 | 0.0027 | 26.56 | 6.768 | 0.3301 | 212277.0 | 153000000 | 126000000000 | 111000000000000 | 0.4295 | 0.1988 | 0.0014 | 0.0022 | 0.0000 | 0.0011 | 0.0177 | 0.0092 | 0.0477 | 0.0152 | 0.1376 | 0.0656 | 0.2030 | 0.1062 | 0.1444 | 0.0846 | 0.1253 | 0.1084 | 0.3229 | 0.6076 | 0.0000 | 0.0014 | 0.0000 | 0.0007 | 0.0010 | 0.0058 | 0.0030 | 0.0093 | 0.0272 | 0.0319 | 0.0495 | 0.0436 | 0.0302 | 0.0367 | 0.0475 | 0.0480 | 0.8417 | 0.8226 | 0.0000 | 0.0019 | 0.0000 | 0.0000 | 0.0039 | 0.0000 | 0.0070 | 0.0056 | 0.0396 | 0.0318 | 0.0591 | 0.0589 | 0.0311 | 0.0308 | 0.0521 | 0.0421 | 0.8073 | 0.8290 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0325 | 0.0644 | 0.0319 | 0.0576 | 0.8081 | 6 | 7 | 9 | 11 | 13 | 17 | 25 | 40 | 85 | 0.1143 | 7.18 | 3.518 | 0.6992 | 4501.5 | 1130000 | 367000000 | 138000000000 | 0.5010 | 0.1794 | 0.0284 | 0.0102 | 0.0869 | 0.0191 | 0.1446 | 0.0339 | 0.1683 | 0.0750 | 0.1629 | 0.1280 | 0.1299 | 0.1522 | 0.1034 | 0.1314 | 0.1052 | 0.1526 | 0.0704 | 0.2976 | 0.0040 | 0.0039 | 0.0059 | 0.0071 | 0.0075 | 0.0092 | 0.0215 | 0.0184 | 0.0557 | 0.0417 | 0.0796 | 0.0708 | 0.0632 | 0.0565 | 0.0866 | 0.0877 | 0.6759 | 0.7047 | 0.0019 | 0.0022 | 0.0019 | 0.0013 | 0.0095 | 0.0056 | 0.0175 | 0.0233 | 0.0712 | 0.0739 | 0.1086 | 0.1188 | 0.0712 | 0.0774 | 0.1036 | 0.1059 | 0.6145 | 0.5916 | 0.0032 | 0.0064 | 0.0051 | 0.0185 | 0.0543 | 0.1006 | 0.0716 | 0.1016 | 0.6387 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 693 | | 1758 | 9747 | 194.5 | 65.03 | 7.39 | 2.56 | 126 | 140 | 153 | 164 | 173 | 189 | 216 | 254 | 297 | 0.0806 | 786 | 1.223 | 29.83 | 11.66 | 2 | 0.0438 | 77 | 0.0089 | 2.56 | 5.059 | 0.5219 | 42048.1 | 10100000 | 2640000000 | 742000000000 | 0.3576 | 0.2730 | 0.0013 | 0.0000 | 0.0053 | 0.0007 | 0.0093 | 0.0043 | 0.0200 | 0.0100 | 0.0787 | 0.0400 | 0.1267 | 0.0557 | 0.1067 | 0.0550 | 0.1440 | 0.0764 | 0.5080 | 0.7580 | 0.0008 | 0.0000 | 0.0034 | 0.0006 | 0.0050 | 0.0024 | 0.0101 | 0.0078 | 0.0378 | 0.0269 | 0.0512 | 0.0305 | 0.0419 | 0.0335 | 0.0680 | 0.0449 | 0.7819 | 0.8533 | 0.0023 | 0.0037 | 0.0000 | 0.0037 | 0.0000 | 0.0000 | 0.0090 | 0.0186 | 0.0498 | 0.0520 | 0.0611 | 0.0892 | 0.0452 | 0.0520 | 0.0656 | 0.0743 | 0.7670 | 0.7063 | 0.0000 | 0.0000 | 0.0030 | 0.0076 | 0.0318 | 0.0636 | 0.0394 | 0.0561 | 0.7985 | 4 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0172 | 8.20 | 4.461 | 0.3585 | 61.1 | 562.508 | 5723.84 | 64032.1 | 0.4837 | 0.1687 | 0.0143 | 0.0020 | 0.0491 | 0.0072 | 0.1154 | 0.0186 | 0.1968 | 0.0459 | 0.2244 | 0.0938 | 0.2015 | 0.1724 | 0.1356 | 0.2637 | 0.0542 | 0.2652 | 0.0087 | 0.1312 | 0.0012 | 0.0000 | 0.0093 | 0.0006 | 0.0270 | 0.0038 | 0.0627 | 0.0130 | 0.1007 | 0.0342 | 0.1357 | 0.0750 | 0.1749 | 0.1500 | 0.2022 | 0.2720 | 0.2862 | 0.4515 | 0.1173 | 0.1778 | 0.1454 | 0.1541 | 0.1396 | 0.1171 | 0.1150 | 0.1141 | 0.1015 | 0.0801 | 0.0904 | 0.0898 | 0.0869 | 0.0746 | 0.0800 | 0.0728 | 0.1238 | 0.1195 | 0.0077 | 0.0301 | 0.0649 | 0.1143 | 0.1463 | 0.1559 | 0.1546 | 0.1313 | 0.1950 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 889 | 579 | | 5344 | 14258 | 479.3 | 73.36 | 59.66 | 126.81 | 384 | 417 | 439 | 460 | 479 | 496 | 514 | 540 | 582 | 0.0560 | 799 | 1.214 | 72.84 | 31.83 | 1 | 0.0378 | 202 | 0.0020 | 11.27 | 6.511 | 0.3208 | 235079.0 | 118000000 | 60300000000 | 31500000000000 | 0.4020 | 0.2453 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0066 | 0.0002 | 0.0216 | 0.0122 | 0.0337 | 0.0213 | 0.0309 | 0.0112 | 0.0475 | 0.0182 | 0.8575 | 0.9369 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0002 | 0.0127 | 0.0122 | 0.0206 | 0.0213 | 0.0145 | 0.0112 | 0.0247 | 0.0167 | 0.9252 | 0.9384 | 0.0000 | 1.0000 | 0.0232 | 0.0000 | 0.0066 | 0.0000 | 0.0381 | 0.0000 | 0.0381 | 0.0000 | 0.0614 | 0.0000 | 0.0779 | 0.0000 | 0.0962 | 0.0000 | 0.6584 | 0.0000 | 0.0019 | 0.0026 | 0.0071 | 0.0160 | 0.0360 | 0.0527 | 0.0605 | 0.0854 | 0.7379 | 6 | 7 | 8 | 9 | 11 | 14 | 23 | 58 | 184 | 0.1961 | 6.16 | 3.029 | 0.6633 | 19637.6 | 11000000 | 8130000000 | 7350000000000 | 0.5394 | 0.1197 | 0.0721 | 0.0088 | 0.1081 | 0.0431 | 0.2450 | 0.1186 | 0.1766 | 0.0958 | 0.1315 | 0.1511 | 0.1045 | 0.1722 | 0.0829 | 0.1178 | 0.0541 | 0.1283 | 0.0252 | 0.1643 | 0.0010 | 0.0000 | 0.0013 | 0.0011 | 0.0048 | 0.0056 | 0.0166 | 0.0189 | 0.0507 | 0.0498 | 0.0842 | 0.0715 | 0.0555 | 0.0540 | 0.0778 | 0.0791 | 0.7083 | 0.7200 | 0.0008 | 0.0004 | 0.0027 | 0.0029 | 0.0023 | 0.0037 | 0.0139 | 0.0166 | 0.0616 | 0.0605 | 0.0953 | 0.0957 | 0.0581 | 0.0609 | 0.0817 | 0.0787 | 0.6836 | 0.6807 | 0.0007 | 0.0021 | 0.0021 | 0.0220 | 0.0535 | 0.0839 | 0.0676 | 0.0740 | 0.6941 | ||
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 187 | 499 | | 5159 | 11813 | 530.2 | 150.73 | 46.53 | 99.31 | 336 | 405 | 473 | 515 | 555 | 600 | 635 | 664 | 696 | 0.0781 | 923 | 1.105 | 73.82 | 25.55 | 4 | 0.0382 | 197 | 0.0006 | 44.92 | 7.570 | 0.1925 | 303806.0 | 182000000 | 112000000000 | 70800000000000 | 0.3690 | 0.2568 | 0.0020 | 0.0000 | 0.0029 | 0.0000 | 0.0069 | 0.0004 | 0.0167 | 0.0024 | 0.0587 | 0.0163 | 0.0953 | 0.0308 | 0.0843 | 0.0238 | 0.1059 | 0.0400 | 0.6273 | 0.8863 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0025 | 0.0021 | 0.0185 | 0.0146 | 0.0285 | 0.0275 | 0.0217 | 0.0173 | 0.0307 | 0.0266 | 0.8966 | 0.9119 | 0.0019 | 0.0635 | 0.0052 | 0.0476 | 0.0110 | 0.1270 | 0.0213 | 0.1429 | 0.0549 | 0.0635 | 0.0614 | 0.1270 | 0.0627 | 0.0952 | 0.1008 | 0.1270 | 0.6807 | 0.2063 | 0.0010 | 0.0024 | 0.0038 | 0.0076 | 0.0244 | 0.0344 | 0.0337 | 0.0485 | 0.8443 | 6 | 8 | 9 | 10 | 11 | 13 | 17 | 52 | 137 | 0.1781 | 7.69 | 3.150 | 0.7073 | 12026.7 | 6360000 | 4770000000 | 4300000000000 | 0.4827 | 0.1912 | 0.0208 | 0.0043 | 0.0655 | 0.0157 | 0.1042 | 0.0386 | 0.1548 | 0.0815 | 0.1935 | 0.1302 | 0.1905 | 0.1774 | 0.1488 | 0.1245 | 0.0893 | 0.1660 | 0.0327 | 0.2618 | 0.0004 | 0.0007 | 0.0004 | 0.0018 | 0.0011 | 0.0036 | 0.0042 | 0.0075 | 0.0229 | 0.0220 | 0.0362 | 0.0341 | 0.0320 | 0.0242 | 0.0526 | 0.0512 | 0.8502 | 0.8550 | 0.0000 | 0.0000 | 0.0022 | 0.0019 | 0.0044 | 0.0033 | 0.0079 | 0.0071 | 0.0271 | 0.0288 | 0.0411 | 0.0506 | 0.0389 | 0.0378 | 0.0599 | 0.0624 | 0.8186 | 0.8080 | 0.0000 | 0.0012 | 0.0032 | 0.0085 | 0.0263 | 0.0388 | 0.0324 | 0.0599 | 0.8297 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 100 | 607 | | 540 | 5580 | 379.2 | 43.12 | 73.69 | 167.23 | 318 | 337 | 353 | 372 | 384 | 393 | 405 | 418 | 436 | 0.0710 | 396 | 0.750 | 109.88 | 35.01 | 2 | 0.6222 | 336 | 0.0034 | 25.50 | 5.823 | 0.2191 | 145633.0 | 56600000 | 22300000000 | 8850000000000 | 0.3869 | 0.2443 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0080 | 0.0019 | 0.0459 | 0.0426 | 0.0719 | 0.0630 | 0.0599 | 0.0315 | 0.0719 | 0.0537 | 0.7405 | 0.8074 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0039 | 0.0019 | 0.0426 | 0.0426 | 0.0638 | 0.0630 | 0.0329 | 0.0315 | 0.0561 | 0.0537 | 0.7988 | 0.8074 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0625 | 0.0000 | 0.1250 | 0.0000 | 0.4375 | 0.0000 | 0.0625 | 0.0000 | 0.2500 | 0.0000 | 0.0625 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0241 | 0.0552 | 0.0897 | 0.0828 | 0.1276 | 0.6138 | 10 | 13 | 15 | 17 | 20 | 25 | 42 | 99 | 162 | 0.2249 | 3.67 | 2.655 | 0.7483 | 33390.0 | 36400000 | 52700000000 | 84800000000000 | 0.5879 | 0.1256 | 0.0385 | 0.0052 | 0.0427 | 0.0174 | 0.1026 | 0.0261 | 0.1880 | 0.0540 | 0.2222 | 0.1237 | 0.1624 | 0.1429 | 0.1496 | 0.1655 | 0.0684 | 0.2003 | 0.0256 | 0.2648 | 0.0007 | 0.0018 | 0.0014 | 0.0043 | 0.0027 | 0.0037 | 0.0075 | 0.0043 | 0.0177 | 0.0178 | 0.0198 | 0.0227 | 0.0355 | 0.0233 | 0.0539 | 0.0491 | 0.8608 | 0.8729 | 0.0000 | 0.0038 | 0.0000 | 0.0028 | 0.0000 | 0.0066 | 0.0154 | 0.0227 | 0.0292 | 0.0360 | 0.0382 | 0.0588 | 0.0544 | 0.0682 | 0.1072 | 0.0986 | 0.7555 | 0.7024 | 0.0007 | 0.0007 | 0.0029 | 0.0059 | 0.0192 | 0.0354 | 0.0347 | 0.0560 | 0.8444 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 977 | 894 | | 8678 | 22119 | 392.0 | 75.13 | 173.89 | 314.23 | 282 | 322 | 354 | 381 | 401 | 420 | 435 | 453 | 485 | 0.0511 | 1131 | 1.201 | 88.96 | 38.42 | 7 | 0.0282 | 245 | 0.0021 | 9.63 | 6.499 | 0.3468 | 159312.0 | 66800000 | 28800000000 | 12700000000000 | 0.4083 | 0.2246 | 0.0002 | 0.0000 | 0.0025 | 0.0000 | 0.0025 | 0.0001 | 0.0084 | 0.0015 | 0.0256 | 0.0120 | 0.0520 | 0.0300 | 0.0441 | 0.0144 | 0.0689 | 0.0254 | 0.7959 | 0.9166 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0007 | 0.0001 | 0.0032 | 0.0014 | 0.0140 | 0.0107 | 0.0286 | 0.0280 | 0.0184 | 0.0113 | 0.0282 | 0.0210 | 0.9063 | 0.9274 | 0.0066 | 0.0000 | 0.0148 | 0.0000 | 0.0206 | 0.0000 | 0.0378 | 0.0000 | 0.0395 | 0.0000 | 0.0625 | 0.0000 | 0.0740 | 0.0000 | 0.0806 | 0.0000 | 0.6637 | 0.0000 | 0.0015 | 0.0023 | 0.0048 | 0.0094 | 0.0270 | 0.0347 | 0.0425 | 0.0628 | 0.8151 | 8 | 9 | 11 | 13 | 17 | 36 | 101 | 281 | 635 | 0.1573 | 22.71 | 4.082 | 0.6152 | 128970.0 | 132000000 | 157000000000 | 209000000000000 | 0.4818 | 0.1310 | 0.0786 | 0.0027 | 0.1743 | 0.0342 | 0.2141 | 0.1218 | 0.1446 | 0.1207 | 0.1503 | 0.1613 | 0.1230 | 0.1795 | 0.0501 | 0.1111 | 0.0353 | 0.1058 | 0.0296 | 0.1629 | 0.0005 | 0.0002 | 0.0003 | 0.0003 | 0.0018 | 0.0015 | 0.0102 | 0.0083 | 0.0355 | 0.0349 | 0.0697 | 0.0563 | 0.0468 | 0.0443 | 0.0615 | 0.0621 | 0.7736 | 0.7921 | 0.0002 | 0.0008 | 0.0014 | 0.0008 | 0.0024 | 0.0030 | 0.0102 | 0.0095 | 0.0454 | 0.0447 | 0.0733 | 0.0818 | 0.0542 | 0.0653 | 0.0806 | 0.0799 | 0.7323 | 0.7140 | 0.0002 | 0.0013 | 0.0044 | 0.0091 | 0.0417 | 0.0714 | 0.0488 | 0.0701 | 0.7531 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 332 | 897 | | 4130 | 6420 | 525.0 | 190.33 | 45.50 | 77.20 | 256 | 314 | 388 | 474 | 542 | 599 | 659 | 716 | 767 | 0.1092 | 701 | 0.638 | 84.10 | 14.14 | 5 | 0.0482 | 199 | 0.0007 | 53.48 | 7.439 | 0.1929 | 311857.0 | 201000000 | 138000000000 | 98300000000000 | 0.3906 | 0.2301 | 0.0000 | 0.0015 | 0.0031 | 0.0011 | 0.0168 | 0.0011 | 0.0291 | 0.0083 | 0.1034 | 0.0496 | 0.1516 | 0.0931 | 0.1309 | 0.0644 | 0.1072 | 0.0966 | 0.4579 | 0.6842 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0018 | 0.0328 | 0.0255 | 0.0470 | 0.0436 | 0.0303 | 0.0252 | 0.0445 | 0.0370 | 0.8418 | 0.8670 | 0.0000 | 0.0015 | 0.0000 | 0.0046 | 0.0021 | 0.0167 | 0.0104 | 0.0410 | 0.0494 | 0.0819 | 0.0626 | 0.1335 | 0.0494 | 0.1108 | 0.0745 | 0.1457 | 0.7516 | 0.4643 | 0.0000 | 0.0005 | 0.0005 | 0.0045 | 0.0352 | 0.0587 | 0.0352 | 0.0564 | 0.8090 | 8 | 10 | 13 | 15 | 17 | 22 | 31 | 60 | 119 | 0.0622 | 10.67 | 3.904 | 0.6364 | 8028.7 | 3400000 | 2280000000 | 1870000000000 | 0.5362 | 0.1440 | 0.0369 | 0.0169 | 0.0844 | 0.0226 | 0.1082 | 0.0463 | 0.1504 | 0.0993 | 0.1847 | 0.1366 | 0.1821 | 0.1061 | 0.1372 | 0.1163 | 0.0976 | 0.1558 | 0.0185 | 0.3002 | 0.0017 | 0.0057 | 0.0034 | 0.0076 | 0.0040 | 0.0086 | 0.0115 | 0.0195 | 0.0453 | 0.0437 | 0.0539 | 0.0518 | 0.0441 | 0.0456 | 0.0648 | 0.0699 | 0.7713 | 0.7476 | 0.0007 | 0.0025 | 0.0029 | 0.0016 | 0.0102 | 0.0074 | 0.0154 | 0.0164 | 0.0469 | 0.0402 | 0.0608 | 0.0731 | 0.0490 | 0.0484 | 0.0791 | 0.0649 | 0.7350 | 0.7455 | 0.0006 | 0.0051 | 0.0058 | 0.0135 | 0.0398 | 0.0630 | 0.0424 | 0.0694 | 0.7603 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 260 | 906 | | 6741 | 5810 | 457.5 | 85.03 | 189.24 | 346.87 | 354 | 397 | 434 | 457 | 471 | 484 | 497 | 515 | 542 | 0.1139 | 662 | 0.726 | 107.34 | 27.78 | 4 | 0.0481 | 324 | 0.0013 | 28.66 | 7.062 | 0.2336 | 216541.0 | 105000000 | 52100000000 | 26300000000000 | 0.4404 | 0.2127 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0038 | 0.0000 | 0.0072 | 0.0011 | 0.0244 | 0.0142 | 0.0415 | 0.0371 | 0.0385 | 0.0169 | 0.0651 | 0.0290 | 0.8182 | 0.9017 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0026 | 0.0000 | 0.0044 | 0.0005 | 0.0175 | 0.0138 | 0.0303 | 0.0338 | 0.0218 | 0.0135 | 0.0322 | 0.0208 | 0.8903 | 0.9176 | 0.0174 | 0.0000 | 0.0209 | 0.0000 | 0.0192 | 0.0000 | 0.0314 | 0.0000 | 0.0401 | 0.0000 | 0.0627 | 0.0000 | 0.0592 | 0.0000 | 0.0941 | 0.0000 | 0.6551 | 0.0000 | 0.0007 | 0.0045 | 0.0057 | 0.0172 | 0.0314 | 0.0528 | 0.0617 | 0.0889 | 0.7372 | 15 | 17 | 18 | 21 | 27 | 55 | 114 | 280 | 602 | 0.2435 | 18.42 | 3.549 | 0.6966 | 156109.0 | 197000000 | 310000000000 | 567000000000000 | 0.6374 | 0.0658 | 0.0763 | 0.0000 | 0.1968 | 0.0329 | 0.2129 | 0.1024 | 0.1566 | 0.1225 | 0.1406 | 0.1846 | 0.1245 | 0.1554 | 0.0482 | 0.1280 | 0.0361 | 0.1188 | 0.0080 | 0.1554 | 0.0013 | 0.0000 | 0.0019 | 0.0006 | 0.0039 | 0.0023 | 0.0142 | 0.0138 | 0.0685 | 0.0619 | 0.0931 | 0.0865 | 0.0672 | 0.0613 | 0.1002 | 0.0980 | 0.6496 | 0.6756 | 0.0008 | 0.0000 | 0.0031 | 0.0025 | 0.0046 | 0.0067 | 0.0208 | 0.0200 | 0.0701 | 0.0835 | 0.1017 | 0.0943 | 0.0770 | 0.0760 | 0.1063 | 0.1077 | 0.6156 | 0.6093 | 0.0000 | 0.0014 | 0.0043 | 0.0157 | 0.0686 | 0.1029 | 0.0657 | 0.1064 | 0.6350 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 895 | 228 | | 1426 | 7457 | 297.1 | 74.97 | 7.35 | 3.00 | 208 | 227 | 244 | 263 | 287 | 309 | 333 | 361 | 411 | 0.0758 | 565 | 1.060 | 52.39 | 17.09 | 1 | 0.0912 | 130 | 0.0050 | 5.81 | 5.550 | 0.3967 | 93879.8 | 31500000 | 11200000000 | 4160000000000 | 0.4025 | 0.2290 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0040 | 0.0008 | 0.0374 | 0.0038 | 0.0602 | 0.0369 | 0.0989 | 0.0638 | 0.0936 | 0.0430 | 0.1283 | 0.0692 | 0.5775 | 0.7809 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0171 | 0.0007 | 0.0286 | 0.0288 | 0.0390 | 0.0400 | 0.0448 | 0.0204 | 0.0524 | 0.0435 | 0.8171 | 0.8667 | 0.0000 | 0.0000 | 0.0066 | 0.0161 | 0.0166 | 0.0000 | 0.0364 | 0.0242 | 0.0530 | 0.1694 | 0.0629 | 0.1774 | 0.0927 | 0.0806 | 0.1060 | 0.2339 | 0.6258 | 0.2984 | 0.0016 | 0.0016 | 0.0109 | 0.0203 | 0.0422 | 0.0422 | 0.0703 | 0.0766 | 0.7344 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 11 | 0.0171 | 9.64 | 4.604 | 0.3424 | 63.0 | 623.07 | 7074.44 | 91176.4 | 0.4927 | 0.1584 | 0.0077 | 0.0045 | 0.0406 | 0.0095 | 0.0981 | 0.0305 | 0.1678 | 0.0652 | 0.2278 | 0.1209 | 0.2100 | 0.1971 | 0.1593 | 0.2556 | 0.0768 | 0.2221 | 0.0121 | 0.0947 | 0.0010 | 0.0002 | 0.0055 | 0.0018 | 0.0185 | 0.0077 | 0.0480 | 0.0279 | 0.0854 | 0.0599 | 0.1434 | 0.1145 | 0.1875 | 0.1703 | 0.2216 | 0.2463 | 0.2890 | 0.3715 | 0.1040 | 0.1438 | 0.1361 | 0.1222 | 0.1301 | 0.0872 | 0.0853 | 0.0745 | 0.0895 | 0.1058 | 0.0811 | 0.0857 | 0.0956 | 0.0842 | 0.0923 | 0.1170 | 0.1860 | 0.1796 | 0.0135 | 0.0521 | 0.0974 | 0.1372 | 0.1573 | 0.1377 | 0.1213 | 0.1143 | 0.1691 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 424 | 598 | | 10118 | 27401 | 44.6 | 15.32 | 9.66 | 10.14 | 26 | 30 | 34 | 39 | 43 | 46 | 51 | 58 | 68 | 0.0697 | 1910 | 0.653 | 52.00 | 10.05 | 2 | 0.0153 | 155 | 0.0320 | 0.80 | 3.734 | 0.7116 | 2220.7 | 121956 | 7260000 | 460000000 | 0.4370 | 0.1928 | 0.0033 | 0.0009 | 0.0117 | 0.0021 | 0.0212 | 0.0062 | 0.0405 | 0.0162 | 0.0660 | 0.0337 | 0.0944 | 0.0462 | 0.1215 | 0.0617 | 0.1775 | 0.0854 | 0.4639 | 0.7475 | 0.0012 | 0.0004 | 0.0041 | 0.0011 | 0.0082 | 0.0029 | 0.0150 | 0.0080 | 0.0223 | 0.0197 | 0.0297 | 0.0256 | 0.0429 | 0.0335 | 0.0634 | 0.0478 | 0.8132 | 0.8611 | 0.0054 | 0.0041 | 0.0122 | 0.0117 | 0.0168 | 0.0233 | 0.0337 | 0.0425 | 0.0471 | 0.0487 | 0.0631 | 0.0720 | 0.0608 | 0.0822 | 0.0838 | 0.0864 | 0.6771 | 0.6292 | 0.0039 | 0.0100 | 0.0142 | 0.0234 | 0.0345 | 0.0395 | 0.0542 | 0.0860 | 0.7342 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 11 | 16 | 0.0607 | 0.27 | 1.084 | 0.3393 | 196.2 | 10715.8 | 1130000 | 163000000 | 0.5653 | 0.1216 | 0.0777 | 0.0043 | 0.1202 | 0.0147 | 0.1403 | 0.0416 | 0.1602 | 0.0819 | 0.1662 | 0.1200 | 0.1599 | 0.1529 | 0.1160 | 0.1781 | 0.0486 | 0.2087 | 0.0109 | 0.1979 | 0.0433 | 0.0019 | 0.0675 | 0.0095 | 0.0728 | 0.0304 | 0.0744 | 0.0626 | 0.0830 | 0.0967 | 0.0877 | 0.1232 | 0.0996 | 0.1307 | 0.1151 | 0.1503 | 0.3566 | 0.3946 | 0.0629 | 0.0327 | 0.0480 | 0.0262 | 0.0487 | 0.0276 | 0.0411 | 0.0316 | 0.0533 | 0.0584 | 0.0696 | 0.0784 | 0.0791 | 0.0835 | 0.1064 | 0.1232 | 0.4909 | 0.5384 | 0.0684 | 0.0635 | 0.0650 | 0.0662 | 0.0726 | 0.0769 | 0.0668 | 0.0896 | 0.4311 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 157 | 329 | | 1738 | 4874 | 829.9 | 218.86 | 12.72 | 6.17 | 545 | 606 | 672 | 746 | 818 | 889 | 972 | 1058 | 1144 | 0.0903 | 440 | 1.050 | 47.54 | 16.03 | 1 | 0.0702 | 122 | 0.0011 | 32.34 | 6.913 | 0.1942 | 736559.0 | 692000000 | 681000000000 | 695000000000000 | 0.3830 | 0.2470 | 0.0000 | 0.0006 | 0.0000 | 0.0006 | 0.0039 | 0.0013 | 0.0209 | 0.0071 | 0.0706 | 0.0292 | 0.1033 | 0.0565 | 0.0928 | 0.0435 | 0.1294 | 0.0617 | 0.5791 | 0.7994 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0057 | 0.0024 | 0.0283 | 0.0209 | 0.0404 | 0.0435 | 0.0323 | 0.0215 | 0.0477 | 0.0316 | 0.8448 | 0.8802 | 0.0021 | 0.0217 | 0.0042 | 0.0145 | 0.0064 | 0.0145 | 0.0169 | 0.0725 | 0.0360 | 0.0870 | 0.0636 | 0.0797 | 0.0487 | 0.1377 | 0.0805 | 0.2101 | 0.7415 | 0.3623 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0311 | 0.0587 | 0.0335 | 0.0467 | 0.8228 | 7 | 8 | 10 | 11 | 12 | 13 | 15 | 16 | 19 | 0.0061 | 22.32 | 5.502 | 0.2607 | 199.8 | 4679.1 | 209109 | 15400000 | 0.5319 | 0.1291 | 0.0389 | 0.0014 | 0.1029 | 0.0079 | 0.1520 | 0.0200 | 0.1856 | 0.0485 | 0.2128 | 0.0891 | 0.1653 | 0.1213 | 0.0976 | 0.2022 | 0.0368 | 0.2799 | 0.0080 | 0.2298 | 0.0185 | 0.0007 | 0.0406 | 0.0045 | 0.0564 | 0.0121 | 0.0554 | 0.0289 | 0.0716 | 0.0535 | 0.0848 | 0.0705 | 0.1039 | 0.1025 | 0.1729 | 0.1735 | 0.3959 | 0.5540 | 0.0744 | 0.1222 | 0.0666 | 0.1109 | 0.1055 | 0.1598 | 0.1038 | 0.1297 | 0.1176 | 0.1297 | 0.1272 | 0.1034 | 0.1375 | 0.1034 | 0.1280 | 0.0658 | 0.1393 | 0.0752 | 0.0362 | 0.0460 | 0.0596 | 0.0732 | 0.0779 | 0.1009 | 0.1300 | 0.2155 | 0.2606 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 742 | 248 | | 1325 | 5484 | 955.8 | 428.77 | 8.01 | 2.97 | 481 | 526 | 610 | 705 | 833 | 1020 | 1224 | 1418 | 1627 | 0.0857 | 470 | 0.902 | 36.72 | 12.08 | 1 | 0.0823 | 109 | 0.0016 | 81.60 | 6.699 | 0.1744 | 1100000.0 | 1440000000 | 2060000000000 | 3.12E+15 | 0.3703 | 0.2538 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0110 | 0.0015 | 0.1801 | 0.0682 | 0.2904 | 0.1091 | 0.1360 | 0.0636 | 0.1324 | 0.1197 | 0.2500 | 0.6348 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0360 | 0.0308 | 0.0596 | 0.0473 | 0.0263 | 0.0226 | 0.0526 | 0.0473 | 0.8241 | 0.8520 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0022 | 0.0128 | 0.0511 | 0.0511 | 0.0644 | 0.0831 | 0.0378 | 0.0511 | 0.0578 | 0.0895 | 0.7867 | 0.7093 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0417 | 0.0609 | 0.0330 | 0.0557 | 0.8070 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 12 | 0.0134 | 9.32 | 4.700 | 0.3378 | 73.0 | 745.296 | 8414.3 | 103808 | 0.4557 | 0.1834 | 0.0246 | 0.0007 | 0.0780 | 0.0051 | 0.1560 | 0.0156 | 0.2275 | 0.0356 | 0.2236 | 0.0749 | 0.1629 | 0.1318 | 0.0948 | 0.2083 | 0.0289 | 0.2962 | 0.0039 | 0.2318 | 0.0045 | 0.0000 | 0.0206 | 0.0000 | 0.0448 | 0.0044 | 0.0775 | 0.0143 | 0.1104 | 0.0457 | 0.1205 | 0.0733 | 0.1415 | 0.1199 | 0.1700 | 0.2262 | 0.3102 | 0.5161 | 0.0910 | 0.1312 | 0.0842 | 0.1131 | 0.0910 | 0.1508 | 0.1045 | 0.1146 | 0.1270 | 0.1071 | 0.1222 | 0.1056 | 0.1283 | 0.1071 | 0.1236 | 0.0920 | 0.1283 | 0.0784 | 0.0246 | 0.0667 | 0.0896 | 0.1051 | 0.0958 | 0.1127 | 0.1221 | 0.1629 | 0.2206 |