High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1182 | 506 | | 5215 | 17071 | 251.9 | 54.05 | 103.06 | 163.53 | 180 | 201 | 217 | 233 | 250 | 266 | 282 | 302 | 327 | 0.0592 | 1011 | 1.075 | 113.14 | 33.02 | 1 | 0.0516 | 269 | 0.0008 | 48.54 | 7.272 | 0.1797 | 66392.4 | 18200000 | 5190000000 | 1520000000000 | 0.4330 | 0.2117 | 0.0006 | 0.0000 | 0.0022 | 0.0000 | 0.0048 | 0.0000 | 0.0275 | 0.0022 | 0.0797 | 0.0138 | 0.1232 | 0.0367 | 0.1331 | 0.0359 | 0.1574 | 0.0648 | 0.4715 | 0.8468 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0077 | 0.0012 | 0.0289 | 0.0106 | 0.0534 | 0.0245 | 0.0530 | 0.0168 | 0.0732 | 0.0315 | 0.7817 | 0.9154 | 0.0029 | 0.0373 | 0.0097 | 0.0683 | 0.0165 | 0.0683 | 0.0584 | 0.1739 | 0.1051 | 0.2050 | 0.1907 | 0.1801 | 0.1430 | 0.1180 | 0.1459 | 0.0745 | 0.3278 | 0.0745 | 0.0004 | 0.0027 | 0.0059 | 0.0212 | 0.0550 | 0.1037 | 0.0923 | 0.1127 | 0.6060 | 8 | 10 | 12 | 14 | 19 | 40 | 88 | 178 | 323 | 0.1315 | 17.54 | 4.370 | 0.5904 | 37361.8 | 20200000 | 13400000000 | 10300000000000 | 0.5718 | 0.1052 | 0.0904 | 0.0025 | 0.2461 | 0.0286 | 0.3176 | 0.1880 | 0.1451 | 0.1835 | 0.0925 | 0.1830 | 0.0641 | 0.1810 | 0.0273 | 0.0847 | 0.0137 | 0.0762 | 0.0032 | 0.0727 | 0.0004 | 0.0000 | 0.0008 | 0.0005 | 0.0013 | 0.0015 | 0.0144 | 0.0131 | 0.0649 | 0.0555 | 0.1011 | 0.0975 | 0.0663 | 0.0604 | 0.0930 | 0.0903 | 0.6578 | 0.6812 | 0.0005 | 0.0005 | 0.0016 | 0.0020 | 0.0060 | 0.0048 | 0.0196 | 0.0218 | 0.0670 | 0.0698 | 0.1097 | 0.1043 | 0.0649 | 0.0698 | 0.0947 | 0.0959 | 0.6360 | 0.6311 | 0.0004 | 0.0010 | 0.0042 | 0.0151 | 0.0692 | 0.1025 | 0.0681 | 0.0903 | 0.6491 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1142 | 279 | | 6081 | 12680 | 333.3 | 75.05 | 132.72 | 150.99 | 244 | 268 | 287 | 305 | 325 | 343 | 366 | 393 | 433 | 0.0758 | 961 | 1.101 | 113.36 | 37.12 | 1 | 0.0462 | 281 | 0.0013 | 26.51 | 6.910 | 0.2088 | 116744.0 | 43000000 | 16600000000 | 6710000000000 | 0.3801 | 0.2654 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0042 | 0.0000 | 0.0168 | 0.0011 | 0.0633 | 0.0200 | 0.1116 | 0.0341 | 0.1355 | 0.0320 | 0.1721 | 0.0541 | 0.4938 | 0.8587 | 0.0004 | 0.0000 | 0.0010 | 0.0000 | 0.0020 | 0.0000 | 0.0071 | 0.0005 | 0.0310 | 0.0141 | 0.0482 | 0.0230 | 0.0586 | 0.0181 | 0.0796 | 0.0318 | 0.7721 | 0.9125 | 0.0037 | 0.0088 | 0.0119 | 0.0117 | 0.0165 | 0.0263 | 0.0567 | 0.0380 | 0.1033 | 0.1082 | 0.1435 | 0.1345 | 0.1060 | 0.0936 | 0.1389 | 0.1082 | 0.4196 | 0.4708 | 0.0018 | 0.0043 | 0.0093 | 0.0205 | 0.0751 | 0.1053 | 0.0830 | 0.1165 | 0.5841 | 10 | 15 | 26 | 48 | 77 | 111 | 158 | 228 | 346 | 0.0156 | 26.28 | 5.931 | 0.4048 | 40411.4 | 17400000 | 9060000000 | 5290000000000 | 0.5025 | 0.1413 | 0.0228 | 0.0017 | 0.0773 | 0.0063 | 0.1471 | 0.0370 | 0.1547 | 0.0783 | 0.1747 | 0.1540 | 0.1485 | 0.1778 | 0.1105 | 0.1249 | 0.0905 | 0.1378 | 0.0739 | 0.2822 | 0.0000 | 0.0006 | 0.0013 | 0.0013 | 0.0013 | 0.0021 | 0.0136 | 0.0091 | 0.0417 | 0.0414 | 0.0724 | 0.0662 | 0.0582 | 0.0462 | 0.0751 | 0.0721 | 0.7364 | 0.7610 | 0.0003 | 0.0006 | 0.0021 | 0.0031 | 0.0040 | 0.0037 | 0.0143 | 0.0131 | 0.0562 | 0.0601 | 0.0816 | 0.1055 | 0.0776 | 0.0812 | 0.1052 | 0.1173 | 0.6588 | 0.6153 | 0.0014 | 0.0020 | 0.0034 | 0.0108 | 0.0473 | 0.0756 | 0.0567 | 0.0882 | 0.7146 | ||
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 895 | 228 | | 1426 | 7457 | 297.1 | 74.97 | 7.35 | 3.00 | 208 | 227 | 244 | 263 | 287 | 309 | 333 | 361 | 411 | 0.0758 | 565 | 1.060 | 52.39 | 17.09 | 1 | 0.0912 | 130 | 0.0050 | 5.81 | 5.550 | 0.3967 | 93879.8 | 31500000 | 11200000000 | 4160000000000 | 0.4025 | 0.2290 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0040 | 0.0008 | 0.0374 | 0.0038 | 0.0602 | 0.0369 | 0.0989 | 0.0638 | 0.0936 | 0.0430 | 0.1283 | 0.0692 | 0.5775 | 0.7809 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0171 | 0.0007 | 0.0286 | 0.0288 | 0.0390 | 0.0400 | 0.0448 | 0.0204 | 0.0524 | 0.0435 | 0.8171 | 0.8667 | 0.0000 | 0.0000 | 0.0066 | 0.0161 | 0.0166 | 0.0000 | 0.0364 | 0.0242 | 0.0530 | 0.1694 | 0.0629 | 0.1774 | 0.0927 | 0.0806 | 0.1060 | 0.2339 | 0.6258 | 0.2984 | 0.0016 | 0.0016 | 0.0109 | 0.0203 | 0.0422 | 0.0422 | 0.0703 | 0.0766 | 0.7344 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 11 | 0.0171 | 9.64 | 4.604 | 0.3424 | 63.0 | 623.07 | 7074.44 | 91176.4 | 0.4927 | 0.1584 | 0.0077 | 0.0045 | 0.0406 | 0.0095 | 0.0981 | 0.0305 | 0.1678 | 0.0652 | 0.2278 | 0.1209 | 0.2100 | 0.1971 | 0.1593 | 0.2556 | 0.0768 | 0.2221 | 0.0121 | 0.0947 | 0.0010 | 0.0002 | 0.0055 | 0.0018 | 0.0185 | 0.0077 | 0.0480 | 0.0279 | 0.0854 | 0.0599 | 0.1434 | 0.1145 | 0.1875 | 0.1703 | 0.2216 | 0.2463 | 0.2890 | 0.3715 | 0.1040 | 0.1438 | 0.1361 | 0.1222 | 0.1301 | 0.0872 | 0.0853 | 0.0745 | 0.0895 | 0.1058 | 0.0811 | 0.0857 | 0.0956 | 0.0842 | 0.0923 | 0.1170 | 0.1860 | 0.1796 | 0.0135 | 0.0521 | 0.0974 | 0.1372 | 0.1573 | 0.1377 | 0.1213 | 0.1143 | 0.1691 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 686 | 761 | | 4278 | 10329 | 575.0 | 101.74 | 209.00 | 348.06 | 451 | 485 | 515 | 540 | 564 | 591 | 619 | 660 | 717 | 0.0947 | 978 | 1.233 | 88.57 | 39.70 | 1 | 0.0570 | 244 | 0.0015 | 26.90 | 6.732 | 0.2213 | 340946.0 | 208000000 | 131000000000 | 85100000000000 | 0.4370 | 0.2089 | 0.0003 | 0.0002 | 0.0016 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0005 | 0.0491 | 0.0165 | 0.1035 | 0.0326 | 0.1032 | 0.0271 | 0.1478 | 0.0398 | 0.5865 | 0.8833 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0005 | 0.0000 | 0.0035 | 0.0002 | 0.0289 | 0.0138 | 0.0516 | 0.0248 | 0.0503 | 0.0145 | 0.0751 | 0.0227 | 0.7893 | 0.9239 | 0.0017 | 0.0000 | 0.0017 | 0.0408 | 0.0166 | 0.0510 | 0.0582 | 0.1633 | 0.1481 | 0.2041 | 0.1681 | 0.2245 | 0.0899 | 0.0714 | 0.1514 | 0.1633 | 0.3644 | 0.0816 | 0.0010 | 0.0000 | 0.0051 | 0.0314 | 0.0663 | 0.1352 | 0.1023 | 0.1180 | 0.5408 | 9 | 10 | 12 | 14 | 19 | 49 | 188 | 394 | 707 | 0.1793 | 74.24 | 4.505 | 0.5801 | 164813.0 | 178000000 | 227000000000 | 323000000000000 | 0.5252 | 0.1228 | 0.1229 | 0.0022 | 0.3301 | 0.0673 | 0.2337 | 0.2076 | 0.1108 | 0.1987 | 0.0723 | 0.2065 | 0.0723 | 0.1358 | 0.0313 | 0.0550 | 0.0193 | 0.0673 | 0.0072 | 0.0595 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0013 | 0.0020 | 0.0041 | 0.0055 | 0.0525 | 0.0486 | 0.0965 | 0.0858 | 0.0600 | 0.0532 | 0.0839 | 0.0776 | 0.7008 | 0.7272 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0014 | 0.0012 | 0.0090 | 0.0196 | 0.0690 | 0.0667 | 0.1063 | 0.1181 | 0.0788 | 0.0895 | 0.1095 | 0.1071 | 0.6259 | 0.5958 | 0.0000 | 0.0003 | 0.0000 | 0.0104 | 0.0509 | 0.1031 | 0.0686 | 0.0961 | 0.6707 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 424 | 598 | | 10118 | 27401 | 44.6 | 15.32 | 9.66 | 10.14 | 26 | 30 | 34 | 39 | 43 | 46 | 51 | 58 | 68 | 0.0697 | 1910 | 0.653 | 52.00 | 10.05 | 2 | 0.0153 | 155 | 0.0320 | 0.80 | 3.734 | 0.7116 | 2220.7 | 121956 | 7260000 | 460000000 | 0.4370 | 0.1928 | 0.0033 | 0.0009 | 0.0117 | 0.0021 | 0.0212 | 0.0062 | 0.0405 | 0.0162 | 0.0660 | 0.0337 | 0.0944 | 0.0462 | 0.1215 | 0.0617 | 0.1775 | 0.0854 | 0.4639 | 0.7475 | 0.0012 | 0.0004 | 0.0041 | 0.0011 | 0.0082 | 0.0029 | 0.0150 | 0.0080 | 0.0223 | 0.0197 | 0.0297 | 0.0256 | 0.0429 | 0.0335 | 0.0634 | 0.0478 | 0.8132 | 0.8611 | 0.0054 | 0.0041 | 0.0122 | 0.0117 | 0.0168 | 0.0233 | 0.0337 | 0.0425 | 0.0471 | 0.0487 | 0.0631 | 0.0720 | 0.0608 | 0.0822 | 0.0838 | 0.0864 | 0.6771 | 0.6292 | 0.0039 | 0.0100 | 0.0142 | 0.0234 | 0.0345 | 0.0395 | 0.0542 | 0.0860 | 0.7342 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 11 | 16 | 0.0607 | 0.27 | 1.084 | 0.3393 | 196.2 | 10715.8 | 1130000 | 163000000 | 0.5653 | 0.1216 | 0.0777 | 0.0043 | 0.1202 | 0.0147 | 0.1403 | 0.0416 | 0.1602 | 0.0819 | 0.1662 | 0.1200 | 0.1599 | 0.1529 | 0.1160 | 0.1781 | 0.0486 | 0.2087 | 0.0109 | 0.1979 | 0.0433 | 0.0019 | 0.0675 | 0.0095 | 0.0728 | 0.0304 | 0.0744 | 0.0626 | 0.0830 | 0.0967 | 0.0877 | 0.1232 | 0.0996 | 0.1307 | 0.1151 | 0.1503 | 0.3566 | 0.3946 | 0.0629 | 0.0327 | 0.0480 | 0.0262 | 0.0487 | 0.0276 | 0.0411 | 0.0316 | 0.0533 | 0.0584 | 0.0696 | 0.0784 | 0.0791 | 0.0835 | 0.1064 | 0.1232 | 0.4909 | 0.5384 | 0.0684 | 0.0635 | 0.0650 | 0.0662 | 0.0726 | 0.0769 | 0.0668 | 0.0896 | 0.4311 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 590 | 585 | | 6499 | 12657 | 474.1 | 105.05 | 39.01 | 84.66 | 344 | 379 | 410 | 438 | 465 | 494 | 525 | 566 | 619 | 0.0658 | 833 | 0.436 | 85.09 | 24.33 | 2 | 0.0495 | 322 | 0.0005 | 98.02 | 7.849 | 0.1181 | 235821.0 | 123000000 | 66600000000 | 37500000000000 | 0.4186 | 0.2373 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0081 | 0.0002 | 0.0234 | 0.0021 | 0.0846 | 0.0185 | 0.1319 | 0.0439 | 0.1403 | 0.0446 | 0.1617 | 0.0662 | 0.4487 | 0.8246 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0075 | 0.0012 | 0.0359 | 0.0131 | 0.0667 | 0.0284 | 0.0658 | 0.0201 | 0.0850 | 0.0339 | 0.7372 | 0.9033 | 0.0024 | 0.0066 | 0.0072 | 0.0197 | 0.0168 | 0.0623 | 0.0455 | 0.1049 | 0.1310 | 0.2164 | 0.1566 | 0.1934 | 0.1054 | 0.1213 | 0.1454 | 0.1016 | 0.3898 | 0.1738 | 0.0007 | 0.0013 | 0.0093 | 0.0251 | 0.0753 | 0.1245 | 0.0951 | 0.1176 | 0.5510 | 8 | 10 | 11 | 13 | 14 | 16 | 20 | 32 | 83 | 0.3458 | 2.93 | 2.365 | 0.7930 | 8689.1 | 4200000 | 2620000000 | 1850000000000 | 0.5811 | 0.1080 | 0.0885 | 0.0104 | 0.2543 | 0.0345 | 0.2812 | 0.1127 | 0.1438 | 0.1577 | 0.1011 | 0.2117 | 0.0616 | 0.1837 | 0.0442 | 0.1186 | 0.0221 | 0.0840 | 0.0032 | 0.0866 | 0.0012 | 0.0043 | 0.0039 | 0.0074 | 0.0075 | 0.0086 | 0.0365 | 0.0296 | 0.0821 | 0.0734 | 0.1147 | 0.0932 | 0.0825 | 0.0839 | 0.1222 | 0.1175 | 0.5495 | 0.5820 | 0.0016 | 0.0023 | 0.0031 | 0.0012 | 0.0047 | 0.0059 | 0.0350 | 0.0457 | 0.0957 | 0.1019 | 0.1479 | 0.1547 | 0.0883 | 0.0873 | 0.1181 | 0.1131 | 0.5055 | 0.4880 | 0.0009 | 0.0059 | 0.0054 | 0.0345 | 0.0917 | 0.1226 | 0.0903 | 0.1207 | 0.5279 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1074 | 329 | | 10716 | 23313 | 347.7 | 91.75 | 73.56 | 114.94 | 242 | 269 | 292 | 314 | 335 | 358 | 384 | 417 | 474 | 0.0592 | 1380 | 0.979 | 123.69 | 46.10 | 1 | 0.0314 | 336 | 0.0009 | 44.10 | 7.309 | 0.1906 | 129299.0 | 51400000 | 21900000000 | 9900000000000 | 0.4246 | 0.2290 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0081 | 0.0003 | 0.0209 | 0.0023 | 0.0739 | 0.0236 | 0.1547 | 0.0469 | 0.1487 | 0.0470 | 0.1829 | 0.0798 | 0.4092 | 0.8000 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0001 | 0.0067 | 0.0011 | 0.0320 | 0.0128 | 0.0693 | 0.0240 | 0.0655 | 0.0222 | 0.0943 | 0.0426 | 0.7287 | 0.8973 | 0.0038 | 0.0033 | 0.0108 | 0.0043 | 0.0169 | 0.0174 | 0.0606 | 0.0587 | 0.0983 | 0.1293 | 0.1396 | 0.1772 | 0.0973 | 0.1283 | 0.1189 | 0.1533 | 0.4537 | 0.3283 | 0.0011 | 0.0027 | 0.0078 | 0.0287 | 0.0782 | 0.1249 | 0.0938 | 0.1276 | 0.5352 | 5 | 6 | 8 | 9 | 13 | 34 | 72 | 133 | 226 | 0.0834 | 10.03 | 3.982 | 0.5196 | 18622.6 | 7300000 | 3800000000 | 2450000000000 | 0.4789 | 0.1814 | 0.0998 | 0.0031 | 0.2338 | 0.0435 | 0.2680 | 0.1682 | 0.1369 | 0.1634 | 0.1119 | 0.1864 | 0.0720 | 0.1590 | 0.0371 | 0.0956 | 0.0306 | 0.0815 | 0.0100 | 0.0993 | 0.0004 | 0.0001 | 0.0003 | 0.0006 | 0.0013 | 0.0018 | 0.0095 | 0.0100 | 0.0610 | 0.0508 | 0.0917 | 0.0745 | 0.0604 | 0.0548 | 0.1046 | 0.0852 | 0.6708 | 0.7222 | 0.0002 | 0.0004 | 0.0018 | 0.0009 | 0.0024 | 0.0034 | 0.0180 | 0.0181 | 0.0720 | 0.0856 | 0.1220 | 0.1315 | 0.0802 | 0.0846 | 0.1175 | 0.1264 | 0.5860 | 0.5492 | 0.0001 | 0.0003 | 0.0026 | 0.0135 | 0.0658 | 0.1063 | 0.0699 | 0.1141 | 0.6274 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1062 | 176 | | 3821 | 1099 | 127.1 | 35.77 | 120.37 | 118.21 | 89 | 99 | 106 | 112 | 119 | 128 | 138 | 153 | 177 | 0.4277 | 470 | 0.928 | 118.11 | 36.14 | 1 | 0.0806 | 308 | 0.0024 | 20.54 | 6.389 | 0.2635 | 17441.2 | 2590000 | 418000000 | 72900000000 | 0.3965 | 0.2480 | 0.0023 | 0.0000 | 0.0014 | 0.0003 | 0.0093 | 0.0021 | 0.0332 | 0.0054 | 0.1037 | 0.0279 | 0.1780 | 0.0722 | 0.1575 | 0.0617 | 0.2164 | 0.0886 | 0.2981 | 0.7418 | 0.0007 | 0.0000 | 0.0003 | 0.0003 | 0.0031 | 0.0008 | 0.0131 | 0.0022 | 0.0475 | 0.0159 | 0.0825 | 0.0401 | 0.0829 | 0.0250 | 0.1186 | 0.0415 | 0.6513 | 0.8743 | 0.0078 | 0.0000 | 0.0065 | 0.0080 | 0.0169 | 0.0239 | 0.0482 | 0.0824 | 0.1172 | 0.1729 | 0.1602 | 0.2154 | 0.1107 | 0.0851 | 0.1549 | 0.1516 | 0.3776 | 0.2606 | 0.0025 | 0.0063 | 0.0163 | 0.0375 | 0.0864 | 0.1183 | 0.0970 | 0.1333 | 0.5025 | 16 | 29 | 41 | 59 | 80 | 108 | 145 | 193 | 282 | 0.0084 | 28.52 | 5.623 | 0.3574 | 28448.3 | 9780000 | 4200000000 | 2070000000000 | 0.4986 | 0.1225 | 0.0743 | 0.0125 | 0.1959 | 0.0498 | 0.2095 | 0.1059 | 0.2162 | 0.1558 | 0.1486 | 0.2118 | 0.0676 | 0.1589 | 0.0811 | 0.0997 | 0.0068 | 0.0903 | 0.0000 | 0.1153 | 0.0041 | 0.0034 | 0.0062 | 0.0102 | 0.0330 | 0.0170 | 0.0433 | 0.0408 | 0.1608 | 0.1548 | 0.1773 | 0.1939 | 0.1361 | 0.1207 | 0.1773 | 0.1531 | 0.2619 | 0.3061 | 0.0089 | 0.0075 | 0.0000 | 0.0037 | 0.0326 | 0.0225 | 0.0742 | 0.1049 | 0.1929 | 0.2060 | 0.1810 | 0.1685 | 0.1721 | 0.1461 | 0.1602 | 0.1648 | 0.1780 | 0.1760 | 0.0025 | 0.0099 | 0.0099 | 0.0591 | 0.1724 | 0.1847 | 0.1576 | 0.1749 | 0.2291 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 414 | 325 | | 5437 | 7882 | 437.9 | 83.20 | 101.98 | 125.88 | 341 | 366 | 387 | 407 | 426 | 445 | 470 | 508 | 561 | 0.1009 | 795 | 1.215 | 56.61 | 22.20 | 1 | 0.0270 | 147 | 0.0013 | 34.95 | 6.913 | 0.2030 | 198637.0 | 93400000 | 45500000000 | 22900000000000 | 0.4444 | 0.2029 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0000 | 0.0120 | 0.0013 | 0.0499 | 0.0139 | 0.1259 | 0.0375 | 0.1288 | 0.0278 | 0.1661 | 0.0447 | 0.5165 | 0.8745 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0047 | 0.0004 | 0.0231 | 0.0107 | 0.0658 | 0.0258 | 0.0594 | 0.0103 | 0.0912 | 0.0214 | 0.7556 | 0.9315 | 0.0000 | 0.0057 | 0.0056 | 0.0230 | 0.0169 | 0.1092 | 0.0666 | 0.1782 | 0.1332 | 0.1494 | 0.1603 | 0.1839 | 0.0971 | 0.1149 | 0.1332 | 0.0977 | 0.3871 | 0.1379 | 0.0013 | 0.0051 | 0.0161 | 0.0442 | 0.0794 | 0.1219 | 0.0968 | 0.1125 | 0.5227 | 6 | 8 | 10 | 15 | 37 | 76 | 132 | 208 | 298 | 0.0817 | 10.67 | 4.715 | 0.5608 | 26243.7 | 8800000 | 3420000000 | 1480000000000 | 0.4564 | 0.1723 | 0.0249 | 0.0017 | 0.0817 | 0.0059 | 0.2664 | 0.0462 | 0.2433 | 0.0891 | 0.1456 | 0.1756 | 0.1155 | 0.2311 | 0.0639 | 0.1395 | 0.0373 | 0.1218 | 0.0213 | 0.1891 | 0.0007 | 0.0003 | 0.0007 | 0.0006 | 0.0029 | 0.0015 | 0.0098 | 0.0052 | 0.0334 | 0.0268 | 0.0579 | 0.0534 | 0.0435 | 0.0365 | 0.0648 | 0.0589 | 0.7863 | 0.8169 | 0.0008 | 0.0000 | 0.0000 | 0.0004 | 0.0016 | 0.0009 | 0.0148 | 0.0152 | 0.0409 | 0.0567 | 0.0678 | 0.0844 | 0.0650 | 0.0612 | 0.0770 | 0.0933 | 0.7319 | 0.6878 | 0.0004 | 0.0015 | 0.0025 | 0.0105 | 0.0384 | 0.0613 | 0.0537 | 0.0758 | 0.7560 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 707 | | 13530 | 19255 | 474.1 | 126.99 | 20.39 | 53.21 | 304 | 394 | 439 | 470 | 494 | 519 | 545 | 573 | 609 | 0.0718 | 1383 | 0.981 | 73.41 | 26.31 | 10 | 0.0152 | 205 | 0.0008 | 44.28 | 7.548 | 0.2080 | 240855.0 | 127000000 | 69400000000 | 38700000000000 | 0.5339 | 0.1308 | 0.0006 | 0.0000 | 0.0010 | 0.0001 | 0.0043 | 0.0006 | 0.0142 | 0.0018 | 0.0585 | 0.0189 | 0.1017 | 0.0371 | 0.0863 | 0.0264 | 0.1091 | 0.0426 | 0.6244 | 0.8725 | 0.0001 | 0.0000 | 0.0002 | 0.0001 | 0.0001 | 0.0000 | 0.0015 | 0.0008 | 0.0170 | 0.0145 | 0.0361 | 0.0292 | 0.0214 | 0.0147 | 0.0347 | 0.0225 | 0.8889 | 0.9183 | 0.0031 | 0.0204 | 0.0058 | 0.0051 | 0.0170 | 0.0636 | 0.0458 | 0.1018 | 0.1021 | 0.1552 | 0.1378 | 0.1578 | 0.1116 | 0.1603 | 0.1412 | 0.1425 | 0.4357 | 0.1934 | 0.0001 | 0.0006 | 0.0021 | 0.0108 | 0.0390 | 0.0782 | 0.0620 | 0.0866 | 0.7204 | 6 | 7 | 8 | 9 | 10 | 11 | 13 | 16 | 31 | 0.4315 | 1.39 | 1.784 | 0.8626 | 3247.0 | 1790000 | 1370000000 | 1200000000000 | 0.6652 | 0.0672 | 0.0808 | 0.0848 | 0.0820 | 0.0869 | 0.1165 | 0.0731 | 0.1440 | 0.0714 | 0.1647 | 0.0831 | 0.1540 | 0.1070 | 0.1277 | 0.1051 | 0.0977 | 0.1288 | 0.0326 | 0.2598 | 0.0277 | 0.0558 | 0.0224 | 0.0571 | 0.0301 | 0.0465 | 0.0388 | 0.0399 | 0.0653 | 0.0505 | 0.0774 | 0.0737 | 0.0629 | 0.0667 | 0.0863 | 0.0911 | 0.5891 | 0.5187 | 0.0078 | 0.0032 | 0.0078 | 0.0050 | 0.0078 | 0.0140 | 0.0168 | 0.0235 | 0.0588 | 0.0587 | 0.0748 | 0.0898 | 0.0643 | 0.0700 | 0.1019 | 0.1020 | 0.6599 | 0.6339 | 0.0183 | 0.0157 | 0.0223 | 0.0265 | 0.0465 | 0.0750 | 0.0550 | 0.0917 | 0.6490 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1116 | 643 | | 4192 | 3538 | 101.2 | 30.48 | 158.91 | 113.21 | 66 | 76 | 84 | 91 | 97 | 104 | 112 | 125 | 141 | 0.1888 | 668 | 0.252 | 105.39 | 16.55 | 4 | 0.1069 | 448 | 0.0013 | 39.51 | 6.913 | 0.1929 | 11171.4 | 1340000 | 175000000 | 24600000000 | 0.4594 | 0.2026 | 0.0014 | 0.0000 | 0.0041 | 0.0009 | 0.0124 | 0.0023 | 0.0464 | 0.0096 | 0.1319 | 0.0422 | 0.1994 | 0.0776 | 0.1641 | 0.0774 | 0.1567 | 0.1235 | 0.2835 | 0.6665 | 0.0006 | 0.0000 | 0.0010 | 0.0005 | 0.0022 | 0.0010 | 0.0128 | 0.0053 | 0.0491 | 0.0264 | 0.0952 | 0.0467 | 0.0789 | 0.0345 | 0.1084 | 0.0632 | 0.6518 | 0.8224 | 0.0000 | 0.0073 | 0.0032 | 0.0218 | 0.0170 | 0.0291 | 0.0668 | 0.1065 | 0.1188 | 0.1574 | 0.1739 | 0.1695 | 0.1294 | 0.1283 | 0.1379 | 0.1259 | 0.3531 | 0.2542 | 0.0016 | 0.0037 | 0.0132 | 0.0390 | 0.0895 | 0.1311 | 0.1101 | 0.1411 | 0.4708 | 37 | 66 | 88 | 111 | 133 | 160 | 195 | 241 | 311 | 0.0052 | 18.73 | 5.833 | 0.3641 | 38065.2 | 12000000 | 4640000000 | 2080000000000 | 0.5210 | 0.1303 | 0.0169 | 0.0013 | 0.0663 | 0.0074 | 0.1808 | 0.0207 | 0.1873 | 0.0702 | 0.1625 | 0.1318 | 0.1443 | 0.1839 | 0.0845 | 0.1498 | 0.0754 | 0.1639 | 0.0819 | 0.2709 | 0.0000 | 0.0000 | 0.0027 | 0.0009 | 0.0038 | 0.0021 | 0.0279 | 0.0141 | 0.0681 | 0.0513 | 0.1217 | 0.0881 | 0.1045 | 0.0783 | 0.1436 | 0.1245 | 0.5279 | 0.6407 | 0.0009 | 0.0047 | 0.0000 | 0.0107 | 0.0119 | 0.0225 | 0.0574 | 0.0664 | 0.1240 | 0.1163 | 0.1559 | 0.1720 | 0.1276 | 0.1139 | 0.1586 | 0.1649 | 0.3637 | 0.3286 | 0.0014 | 0.0028 | 0.0104 | 0.0369 | 0.0828 | 0.1711 | 0.1113 | 0.1474 | 0.4360 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 972 | 297 | | 4771 | 7211 | 303.5 | 65.31 | 240.93 | 226.65 | 218 | 246 | 266 | 285 | 301 | 318 | 336 | 359 | 393 | 0.1144 | 825 | 0.746 | 99.85 | 18.25 | 1 | 0.0470 | 224 | 0.0006 | 79.54 | 7.546 | 0.1380 | 96372.4 | 31900000 | 11000000000 | 3900000000000 | 0.4166 | 0.2336 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0180 | 0.0018 | 0.0709 | 0.0195 | 0.1275 | 0.0424 | 0.1468 | 0.0462 | 0.1774 | 0.0735 | 0.4551 | 0.8167 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0004 | 0.0315 | 0.0150 | 0.0601 | 0.0295 | 0.0668 | 0.0242 | 0.0840 | 0.0406 | 0.7492 | 0.8903 | 0.0069 | 0.0237 | 0.0183 | 0.0473 | 0.0171 | 0.1065 | 0.0674 | 0.1598 | 0.1063 | 0.2189 | 0.1337 | 0.1479 | 0.1029 | 0.0651 | 0.1349 | 0.0947 | 0.4126 | 0.1361 | 0.0004 | 0.0004 | 0.0056 | 0.0299 | 0.0837 | 0.1205 | 0.1008 | 0.1166 | 0.5421 | 18 | 24 | 51 | 105 | 176 | 253 | 344 | 445 | 581 | 0.0200 | 42.53 | 6.319 | 0.3498 | 109411.0 | 62100000 | 40100000000 | 28400000000000 | 0.5244 | 0.1362 | 0.0141 | 0.0041 | 0.1315 | 0.0113 | 0.1984 | 0.0504 | 0.1737 | 0.0989 | 0.2007 | 0.1819 | 0.1080 | 0.2044 | 0.0869 | 0.1380 | 0.0552 | 0.1220 | 0.0317 | 0.1890 | 0.0003 | 0.0000 | 0.0020 | 0.0008 | 0.0014 | 0.0013 | 0.0098 | 0.0072 | 0.0571 | 0.0424 | 0.0704 | 0.0721 | 0.0637 | 0.0570 | 0.0947 | 0.0816 | 0.7006 | 0.7377 | 0.0004 | 0.0005 | 0.0023 | 0.0027 | 0.0104 | 0.0068 | 0.0154 | 0.0263 | 0.0677 | 0.0693 | 0.0903 | 0.1014 | 0.0765 | 0.0928 | 0.1107 | 0.1241 | 0.6263 | 0.5761 | 0.0003 | 0.0027 | 0.0020 | 0.0140 | 0.0578 | 0.0905 | 0.0708 | 0.1002 | 0.6617 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 849 | 462 | | 6757 | 10694 | 103.6 | 26.81 | 127.16 | 113.08 | 75 | 82 | 88 | 93 | 98 | 104 | 112 | 123 | 140 | 0.0902 | 965 | 1.167 | 103.82 | 31.40 | 1 | 0.0364 | 246 | 0.0039 | 11.91 | 5.964 | 0.3215 | 11459.3 | 1360000 | 172000000 | 23500000000 | 0.4214 | 0.2299 | 0.0010 | 0.0000 | 0.0030 | 0.0000 | 0.0088 | 0.0010 | 0.0340 | 0.0029 | 0.0862 | 0.0218 | 0.1582 | 0.0506 | 0.1512 | 0.0465 | 0.1907 | 0.0759 | 0.3668 | 0.8013 | 0.0006 | 0.0000 | 0.0013 | 0.0000 | 0.0044 | 0.0003 | 0.0169 | 0.0005 | 0.0417 | 0.0128 | 0.0730 | 0.0254 | 0.0763 | 0.0197 | 0.1012 | 0.0369 | 0.6846 | 0.9045 | 0.0039 | 0.0036 | 0.0093 | 0.0000 | 0.0171 | 0.0342 | 0.0497 | 0.0739 | 0.0994 | 0.1586 | 0.1654 | 0.2036 | 0.1165 | 0.1243 | 0.1405 | 0.1333 | 0.3983 | 0.2685 | 0.0040 | 0.0058 | 0.0112 | 0.0426 | 0.0834 | 0.1119 | 0.0888 | 0.1241 | 0.5283 | 17 | 32 | 49 | 71 | 97 | 124 | 158 | 204 | 276 | 0.0049 | 28.88 | 6.477 | 0.3379 | 28954.2 | 9110000 | 3510000000 | 1540000000000 | 0.5010 | 0.1908 | 0.0104 | 0.0014 | 0.0825 | 0.0080 | 0.1622 | 0.0280 | 0.1715 | 0.0704 | 0.1802 | 0.1431 | 0.1846 | 0.1949 | 0.0978 | 0.1574 | 0.0672 | 0.1528 | 0.0437 | 0.2441 | 0.0002 | 0.0005 | 0.0006 | 0.0006 | 0.0043 | 0.0027 | 0.0166 | 0.0116 | 0.0621 | 0.0488 | 0.1025 | 0.0778 | 0.0847 | 0.0716 | 0.1177 | 0.0936 | 0.6114 | 0.6925 | 0.0027 | 0.0022 | 0.0036 | 0.0056 | 0.0141 | 0.0086 | 0.0335 | 0.0365 | 0.0847 | 0.0941 | 0.1182 | 0.1391 | 0.0972 | 0.0926 | 0.1152 | 0.1183 | 0.5308 | 0.5030 | 0.0007 | 0.0021 | 0.0060 | 0.0293 | 0.0767 | 0.1199 | 0.0870 | 0.1146 | 0.5636 | ||
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 837 | 568 | | 3810 | 7691 | 452.3 | 131.47 | 221.21 | 376.57 | 230 | 356 | 426 | 457 | 480 | 503 | 528 | 553 | 586 | 0.0787 | 605 | 1.031 | 95.27 | 22.00 | 2 | 0.0559 | 213 | 0.0026 | 14.07 | 6.352 | 0.2995 | 221894.0 | 114000000 | 60800000000 | 33200000000000 | 0.3620 | 0.2645 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0029 | 0.0000 | 0.0119 | 0.0016 | 0.0530 | 0.0188 | 0.0759 | 0.0350 | 0.0740 | 0.0220 | 0.1050 | 0.0373 | 0.6765 | 0.8854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0145 | 0.0142 | 0.0290 | 0.0275 | 0.0145 | 0.0133 | 0.0244 | 0.0245 | 0.9162 | 0.9198 | 0.0021 | 0.0000 | 0.0054 | 0.0122 | 0.0171 | 0.0000 | 0.0289 | 0.0427 | 0.0567 | 0.1037 | 0.0739 | 0.0732 | 0.1017 | 0.1220 | 0.1210 | 0.0793 | 0.5931 | 0.5671 | 0.0004 | 0.0017 | 0.0021 | 0.0084 | 0.0261 | 0.0433 | 0.0517 | 0.0685 | 0.7977 | 9 | 14 | 18 | 23 | 32 | 56 | 165 | 387 | 734 | 0.0801 | 36.23 | 4.662 | 0.5714 | 190720.0 | 231000000 | 326000000000 | 505000000000000 | 0.5310 | 0.1283 | 0.0284 | 0.0000 | 0.2074 | 0.0058 | 0.3466 | 0.0902 | 0.1307 | 0.1645 | 0.1392 | 0.2082 | 0.0881 | 0.2475 | 0.0256 | 0.1092 | 0.0227 | 0.0975 | 0.0114 | 0.0771 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0008 | 0.0089 | 0.0041 | 0.0491 | 0.0454 | 0.0930 | 0.0827 | 0.0637 | 0.0458 | 0.0885 | 0.0827 | 0.6963 | 0.7387 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0052 | 0.0017 | 0.0063 | 0.0112 | 0.0645 | 0.0730 | 0.1096 | 0.1162 | 0.0739 | 0.0691 | 0.1070 | 0.1072 | 0.6329 | 0.6199 | 0.0000 | 0.0005 | 0.0029 | 0.0082 | 0.0629 | 0.0936 | 0.0739 | 0.0975 | 0.6606 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 799 | 497 | | 16816 | 24748 | 122.3 | 34.96 | 236.76 | 206.30 | 82 | 94 | 102 | 110 | 118 | 126 | 136 | 149 | 168 | 0.0650 | 1609 | 1.118 | 72.20 | 25.02 | 3 | 0.0108 | 181 | 0.0021 | 18.82 | 6.539 | 0.2763 | 16190.9 | 2320000 | 358000000 | 60000000000 | 0.4389 | 0.2098 | 0.0010 | 0.0001 | 0.0025 | 0.0003 | 0.0091 | 0.0014 | 0.0328 | 0.0040 | 0.0891 | 0.0250 | 0.1521 | 0.0565 | 0.1545 | 0.0597 | 0.1758 | 0.0901 | 0.3831 | 0.7630 | 0.0004 | 0.0001 | 0.0005 | 0.0000 | 0.0026 | 0.0002 | 0.0095 | 0.0013 | 0.0356 | 0.0130 | 0.0650 | 0.0262 | 0.0618 | 0.0238 | 0.0849 | 0.0395 | 0.7396 | 0.8959 | 0.0031 | 0.0096 | 0.0075 | 0.0071 | 0.0173 | 0.0199 | 0.0537 | 0.1065 | 0.1221 | 0.1508 | 0.1553 | 0.2060 | 0.1205 | 0.1232 | 0.1477 | 0.1521 | 0.3728 | 0.2246 | 0.0013 | 0.0031 | 0.0088 | 0.0298 | 0.0749 | 0.1135 | 0.0977 | 0.1296 | 0.5413 | 21 | 45 | 86 | 134 | 187 | 246 | 312 | 397 | 532 | 0.0053 | 78.87 | 7.190 | 0.2785 | 98609.0 | 53500000 | 34300000000 | 24800000000000 | 0.5106 | 0.1669 | 0.0256 | 0.0012 | 0.1110 | 0.0083 | 0.2322 | 0.0422 | 0.1927 | 0.1005 | 0.1604 | 0.1805 | 0.1290 | 0.2104 | 0.0825 | 0.1584 | 0.0439 | 0.1366 | 0.0227 | 0.1620 | 0.0004 | 0.0002 | 0.0009 | 0.0012 | 0.0050 | 0.0019 | 0.0154 | 0.0099 | 0.0609 | 0.0492 | 0.1064 | 0.0949 | 0.0889 | 0.0752 | 0.1192 | 0.1063 | 0.6028 | 0.6612 | 0.0004 | 0.0013 | 0.0032 | 0.0039 | 0.0100 | 0.0142 | 0.0294 | 0.0412 | 0.0896 | 0.1025 | 0.1454 | 0.1529 | 0.1084 | 0.1139 | 0.1346 | 0.1366 | 0.4791 | 0.4335 | 0.0001 | 0.0020 | 0.0079 | 0.0209 | 0.0743 | 0.1266 | 0.1001 | 0.1318 | 0.5361 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 214 | 329 | | 2935 | 11303 | 279.9 | 61.40 | 6.40 | 2.56 | 193 | 217 | 240 | 262 | 283 | 300 | 320 | 339 | 363 | 0.0572 | 646 | 0.707 | 220.60 | 68.41 | 1 | 0.2290 | 672 | 0.0038 | 5.82 | 5.792 | 0.3874 | 82100.6 | 25100000 | 7920000000 | 2580000000000 | 0.3742 | 0.2640 | 0.0012 | 0.0000 | 0.0055 | 0.0000 | 0.0068 | 0.0003 | 0.0197 | 0.0035 | 0.0419 | 0.0219 | 0.0653 | 0.0299 | 0.0635 | 0.0285 | 0.1054 | 0.0597 | 0.6907 | 0.8563 | 0.0009 | 0.0000 | 0.0018 | 0.0000 | 0.0013 | 0.0003 | 0.0075 | 0.0027 | 0.0168 | 0.0196 | 0.0266 | 0.0240 | 0.0239 | 0.0192 | 0.0350 | 0.0343 | 0.8862 | 0.8998 | 0.0031 | 0.1875 | 0.0126 | 0.2813 | 0.0173 | 0.3750 | 0.0346 | 0.0938 | 0.0456 | 0.0625 | 0.0566 | 0.0000 | 0.0629 | 0.0000 | 0.0849 | 0.0000 | 0.6824 | 0.0000 | 0.0013 | 0.0020 | 0.0059 | 0.0092 | 0.0277 | 0.0323 | 0.0323 | 0.0554 | 0.8339 | 3 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 10 | 0.4396 | 0.38 | 1.169 | 0.8081 | 47.5 | 391.249 | 3512.14 | 33881.8 | 0.4867 | 0.1660 | 0.0087 | 0.0004 | 0.0533 | 0.0075 | 0.1339 | 0.0348 | 0.2382 | 0.1039 | 0.2579 | 0.1830 | 0.1883 | 0.2424 | 0.0921 | 0.2426 | 0.0230 | 0.1419 | 0.0046 | 0.0434 | 0.0002 | 0.0000 | 0.0018 | 0.0009 | 0.0097 | 0.0035 | 0.0393 | 0.0162 | 0.0799 | 0.0427 | 0.1426 | 0.0876 | 0.2155 | 0.1902 | 0.2757 | 0.3292 | 0.2352 | 0.3297 | 0.0810 | 0.1861 | 0.1648 | 0.2753 | 0.2049 | 0.2537 | 0.1900 | 0.1433 | 0.1511 | 0.0792 | 0.1073 | 0.0385 | 0.0628 | 0.0186 | 0.0300 | 0.0043 | 0.0081 | 0.0009 | 0.0035 | 0.0243 | 0.0659 | 0.1244 | 0.1728 | 0.2058 | 0.2030 | 0.1370 | 0.0633 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 916 | 643 | | 6177 | 7967 | 199.4 | 44.34 | 175.07 | 133.71 | 150 | 163 | 173 | 182 | 192 | 203 | 216 | 234 | 259 | 0.0964 | 768 | 0.994 | 106.57 | 33.42 | 1 | 0.0440 | 272 | 0.0013 | 36.60 | 6.944 | 0.1957 | 41711.5 | 9180000 | 2130000000 | 520000000000 | 0.4243 | 0.2275 | 0.0010 | 0.0000 | 0.0007 | 0.0000 | 0.0032 | 0.0000 | 0.0168 | 0.0009 | 0.0753 | 0.0176 | 0.1308 | 0.0425 | 0.1402 | 0.0375 | 0.1836 | 0.0678 | 0.4482 | 0.8336 | 0.0006 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0000 | 0.0076 | 0.0005 | 0.0326 | 0.0112 | 0.0591 | 0.0230 | 0.0595 | 0.0150 | 0.0870 | 0.0231 | 0.7518 | 0.9272 | 0.0009 | 0.0179 | 0.0091 | 0.0358 | 0.0174 | 0.0657 | 0.0659 | 0.1343 | 0.1473 | 0.1433 | 0.1738 | 0.1791 | 0.1363 | 0.0955 | 0.1537 | 0.1164 | 0.2955 | 0.2119 | 0.0011 | 0.0033 | 0.0110 | 0.0375 | 0.0824 | 0.1191 | 0.1085 | 0.1393 | 0.4978 | 30 | 56 | 84 | 112 | 145 | 182 | 223 | 277 | 360 | 0.0025 | 69.87 | 6.927 | 0.2586 | 48522.6 | 17600000 | 7750000000 | 3970000000000 | 0.4873 | 0.1778 | 0.0220 | 0.0017 | 0.1111 | 0.0031 | 0.1870 | 0.0584 | 0.1544 | 0.1117 | 0.1816 | 0.1633 | 0.1457 | 0.1879 | 0.0951 | 0.1507 | 0.0552 | 0.1240 | 0.0479 | 0.1992 | 0.0002 | 0.0004 | 0.0014 | 0.0006 | 0.0029 | 0.0018 | 0.0145 | 0.0127 | 0.0737 | 0.0543 | 0.1090 | 0.0980 | 0.0872 | 0.0692 | 0.1206 | 0.1000 | 0.5904 | 0.6629 | 0.0015 | 0.0034 | 0.0019 | 0.0029 | 0.0087 | 0.0147 | 0.0417 | 0.0563 | 0.1059 | 0.1337 | 0.1647 | 0.1768 | 0.1097 | 0.1254 | 0.1514 | 0.1528 | 0.4144 | 0.3340 | 0.0006 | 0.0033 | 0.0072 | 0.0275 | 0.0899 | 0.1341 | 0.1039 | 0.1338 | 0.4997 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1125 | 641 | | 11752 | 25342 | 232.5 | 61.19 | 170.59 | 255.96 | 162 | 186 | 201 | 215 | 228 | 242 | 257 | 278 | 310 | 0.0510 | 1293 | 1.092 | 30.46 | 9.43 | 3 | 0.0062 | 73 | 0.0008 | 52.10 | 7.510 | 0.1713 | 57786.2 | 15300000 | 4280000000 | 1270000000000 | 0.4266 | 0.2087 | 0.0003 | 0.0000 | 0.0011 | 0.0002 | 0.0038 | 0.0004 | 0.0137 | 0.0016 | 0.0570 | 0.0194 | 0.1221 | 0.0376 | 0.1242 | 0.0374 | 0.1725 | 0.0532 | 0.5053 | 0.8503 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0015 | 0.0000 | 0.0056 | 0.0005 | 0.0238 | 0.0113 | 0.0480 | 0.0188 | 0.0513 | 0.0158 | 0.0752 | 0.0235 | 0.7940 | 0.9300 | 0.0039 | 0.0023 | 0.0117 | 0.0081 | 0.0174 | 0.0151 | 0.0516 | 0.0755 | 0.0951 | 0.1231 | 0.1428 | 0.1649 | 0.0872 | 0.1115 | 0.1228 | 0.1161 | 0.4674 | 0.3833 | 0.0018 | 0.0029 | 0.0093 | 0.0250 | 0.0622 | 0.0988 | 0.0949 | 0.1131 | 0.5921 | 9 | 12 | 17 | 32 | 58 | 95 | 152 | 272 | 534 | 0.0689 | 34.29 | 5.267 | 0.5297 | 94612.1 | 77200000 | 75700000000 | 83200000000000 | 0.3585 | 0.3278 | 0.0395 | 0.0012 | 0.1512 | 0.0108 | 0.2256 | 0.0794 | 0.1461 | 0.1072 | 0.1502 | 0.1684 | 0.1169 | 0.1823 | 0.0707 | 0.1281 | 0.0608 | 0.1168 | 0.0390 | 0.2056 | 0.0006 | 0.0003 | 0.0021 | 0.0014 | 0.0038 | 0.0026 | 0.0153 | 0.0136 | 0.0581 | 0.0480 | 0.0869 | 0.0812 | 0.0666 | 0.0586 | 0.0861 | 0.0828 | 0.6805 | 0.7116 | 0.0002 | 0.0007 | 0.0019 | 0.0034 | 0.0056 | 0.0081 | 0.0251 | 0.0236 | 0.0640 | 0.0649 | 0.0941 | 0.0908 | 0.0674 | 0.0685 | 0.0855 | 0.0777 | 0.6563 | 0.6622 | 0.0007 | 0.0013 | 0.0062 | 0.0194 | 0.0623 | 0.0938 | 0.0645 | 0.0859 | 0.6660 | ||
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 429 | 152 | | 5147 | 13190 | 300.5 | 77.17 | 108.66 | 110.80 | 212 | 234 | 254 | 271 | 289 | 308 | 329 | 359 | 403 | 0.0728 | 960 | 0.674 | 104.17 | 19.70 | 1 | 0.0492 | 253 | 0.0006 | 94.37 | 7.666 | 0.1240 | 96226.5 | 32900000 | 12000000000 | 4710000000000 | 0.3982 | 0.2452 | 0.0017 | 0.0000 | 0.0014 | 0.0000 | 0.0024 | 0.0000 | 0.0279 | 0.0028 | 0.0927 | 0.0245 | 0.1714 | 0.0507 | 0.1714 | 0.0507 | 0.1830 | 0.0752 | 0.3480 | 0.7962 | 0.0013 | 0.0000 | 0.0005 | 0.0000 | 0.0018 | 0.0000 | 0.0109 | 0.0012 | 0.0344 | 0.0148 | 0.0725 | 0.0281 | 0.0803 | 0.0224 | 0.0990 | 0.0368 | 0.6993 | 0.8967 | 0.0020 | 0.0026 | 0.0107 | 0.0104 | 0.0176 | 0.0260 | 0.0547 | 0.0935 | 0.1270 | 0.1636 | 0.1680 | 0.1896 | 0.1240 | 0.1221 | 0.1416 | 0.1377 | 0.3545 | 0.2545 | 0.0004 | 0.0031 | 0.0118 | 0.0298 | 0.0815 | 0.1333 | 0.1109 | 0.1337 | 0.4954 | 12 | 16 | 22 | 38 | 65 | 103 | 146 | 200 | 271 | 0.0288 | 11.68 | 5.216 | 0.4837 | 24083.1 | 7070000 | 2440000000 | 950000000000 | 0.4467 | 0.1953 | 0.0280 | 0.0011 | 0.1405 | 0.0047 | 0.2943 | 0.0614 | 0.1729 | 0.1210 | 0.1545 | 0.2201 | 0.0890 | 0.2000 | 0.0655 | 0.1325 | 0.0361 | 0.1174 | 0.0191 | 0.1418 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0011 | 0.0117 | 0.0076 | 0.0534 | 0.0462 | 0.0876 | 0.0766 | 0.0602 | 0.0517 | 0.0834 | 0.0797 | 0.7018 | 0.7371 | 0.0014 | 0.0008 | 0.0016 | 0.0011 | 0.0036 | 0.0074 | 0.0216 | 0.0198 | 0.0664 | 0.0805 | 0.1074 | 0.1116 | 0.0767 | 0.0818 | 0.1035 | 0.1076 | 0.6178 | 0.5896 | 0.0002 | 0.0006 | 0.0020 | 0.0129 | 0.0649 | 0.0943 | 0.0672 | 0.0976 | 0.6603 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1093 | 541 | | 6510 | 19083 | 329.3 | 67.71 | 96.25 | 108.79 | 246 | 270 | 288 | 306 | 322 | 340 | 362 | 390 | 424 | 0.0512 | 978 | 1.154 | 97.62 | 37.11 | 1 | 0.0393 | 256 | 0.0013 | 28.44 | 6.892 | 0.2102 | 112993.0 | 40300000 | 14900000000 | 5720000000000 | 0.4415 | 0.2097 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0043 | 0.0003 | 0.0149 | 0.0014 | 0.0652 | 0.0158 | 0.1269 | 0.0341 | 0.1409 | 0.0340 | 0.1777 | 0.0597 | 0.4684 | 0.8547 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0018 | 0.0000 | 0.0065 | 0.0002 | 0.0277 | 0.0116 | 0.0554 | 0.0212 | 0.0606 | 0.0158 | 0.0862 | 0.0306 | 0.7611 | 0.9207 | 0.0042 | 0.0157 | 0.0067 | 0.0000 | 0.0177 | 0.0627 | 0.0725 | 0.1412 | 0.1197 | 0.1961 | 0.1594 | 0.1843 | 0.1197 | 0.1451 | 0.1476 | 0.1451 | 0.3524 | 0.1098 | 0.0013 | 0.0033 | 0.0086 | 0.0309 | 0.0800 | 0.1165 | 0.1009 | 0.1201 | 0.5385 | 7 | 9 | 12 | 27 | 55 | 86 | 127 | 179 | 256 | 0.0642 | 12.35 | 5.075 | 0.5282 | 21099.1 | 6350000 | 2360000000 | 1030000000000 | 0.4788 | 0.1572 | 0.0140 | 0.0020 | 0.0726 | 0.0070 | 0.1767 | 0.0276 | 0.1707 | 0.0700 | 0.1712 | 0.1521 | 0.1612 | 0.1785 | 0.0996 | 0.1459 | 0.0776 | 0.1537 | 0.0566 | 0.2631 | 0.0004 | 0.0001 | 0.0007 | 0.0005 | 0.0036 | 0.0013 | 0.0080 | 0.0073 | 0.0353 | 0.0283 | 0.0641 | 0.0499 | 0.0529 | 0.0434 | 0.0741 | 0.0687 | 0.7611 | 0.8004 | 0.0005 | 0.0002 | 0.0015 | 0.0007 | 0.0028 | 0.0046 | 0.0118 | 0.0137 | 0.0486 | 0.0587 | 0.0819 | 0.0869 | 0.0679 | 0.0845 | 0.1039 | 0.1128 | 0.6810 | 0.6378 | 0.0004 | 0.0006 | 0.0017 | 0.0103 | 0.0404 | 0.0685 | 0.0604 | 0.0855 | 0.7323 | ||
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 844 | 729 | | 5195 | 6746 | 513.2 | 118.34 | 131.41 | 201.76 | 374 | 422 | 455 | 484 | 509 | 533 | 559 | 598 | 663 | 0.1269 | 856 | 1.179 | 136.50 | 52.00 | 4 | 0.0670 | 348 | 0.0006 | 81.67 | 7.590 | 0.1403 | 277409.0 | 157000000 | 93300000000 | 57800000000000 | 0.4641 | 0.1828 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0092 | 0.0002 | 0.0187 | 0.0015 | 0.0728 | 0.0317 | 0.1260 | 0.0589 | 0.1091 | 0.0502 | 0.1534 | 0.0757 | 0.5108 | 0.7819 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0037 | 0.0008 | 0.0387 | 0.0254 | 0.0701 | 0.0404 | 0.0576 | 0.0258 | 0.0831 | 0.0416 | 0.7456 | 0.8661 | 0.0059 | 0.0100 | 0.0118 | 0.0134 | 0.0178 | 0.0334 | 0.0675 | 0.1104 | 0.1349 | 0.1371 | 0.1527 | 0.1605 | 0.0982 | 0.1171 | 0.1396 | 0.1371 | 0.3716 | 0.2809 | 0.0012 | 0.0020 | 0.0083 | 0.0313 | 0.0944 | 0.1583 | 0.1035 | 0.1432 | 0.4578 | 7 | 9 | 11 | 15 | 30 | 63 | 128 | 229 | 416 | 0.1248 | 27.25 | 4.487 | 0.5729 | 57968.2 | 37400000 | 29800000000 | 27700000000000 | 0.6421 | 0.0717 | 0.0374 | 0.0045 | 0.1828 | 0.0269 | 0.3106 | 0.1256 | 0.1806 | 0.1469 | 0.1564 | 0.2096 | 0.0639 | 0.2096 | 0.0419 | 0.1188 | 0.0176 | 0.0953 | 0.0088 | 0.0628 | 0.0000 | 0.0004 | 0.0004 | 0.0024 | 0.0009 | 0.0028 | 0.0121 | 0.0108 | 0.0689 | 0.0667 | 0.1123 | 0.0895 | 0.0671 | 0.0667 | 0.0988 | 0.0927 | 0.6395 | 0.6681 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0028 | 0.0050 | 0.0213 | 0.0292 | 0.0786 | 0.0856 | 0.1296 | 0.1290 | 0.0836 | 0.0862 | 0.1072 | 0.1141 | 0.5758 | 0.5509 | 0.0000 | 0.0010 | 0.0035 | 0.0180 | 0.0721 | 0.1181 | 0.0756 | 0.1086 | 0.6031 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1168 | 309 | | 5738 | 14541 | 555.0 | 97.99 | 135.57 | 201.88 | 430 | 475 | 509 | 532 | 549 | 569 | 595 | 630 | 674 | 0.0558 | 812 | 1.022 | 61.39 | 19.31 | 1 | 0.0284 | 163 | 0.0013 | 20.75 | 6.963 | 0.2451 | 317645.0 | 187000000 | 114000000000 | 71800000000000 | 0.4110 | 0.2319 | 0.0002 | 0.0000 | 0.0005 | 0.0002 | 0.0016 | 0.0000 | 0.0094 | 0.0011 | 0.0237 | 0.0134 | 0.0434 | 0.0246 | 0.0556 | 0.0175 | 0.0657 | 0.0266 | 0.8000 | 0.9168 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0002 | 0.0111 | 0.0115 | 0.0231 | 0.0207 | 0.0271 | 0.0101 | 0.0293 | 0.0171 | 0.9045 | 0.9404 | 0.0060 | 0.0000 | 0.0119 | 0.0000 | 0.0179 | 0.0000 | 0.0448 | 0.0000 | 0.0746 | 0.0000 | 0.0896 | 0.0000 | 0.0940 | 0.0000 | 0.1284 | 0.0000 | 0.5328 | 0.0000 | 0.0037 | 0.0078 | 0.0108 | 0.0257 | 0.0310 | 0.0518 | 0.0567 | 0.0712 | 0.7411 | 6 | 9 | 11 | 15 | 31 | 63 | 129 | 257 | 447 | 0.0557 | 17.52 | 4.450 | 0.4770 | 59131.7 | 35000000 | 24100000000 | 18500000000000 | 0.2802 | 0.3316 | 0.0685 | 0.0029 | 0.2066 | 0.0315 | 0.2433 | 0.1562 | 0.1601 | 0.1358 | 0.1039 | 0.1713 | 0.0844 | 0.1871 | 0.0648 | 0.1125 | 0.0391 | 0.0857 | 0.0293 | 0.1171 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0017 | 0.0011 | 0.0106 | 0.0101 | 0.0494 | 0.0398 | 0.0811 | 0.0787 | 0.0552 | 0.0482 | 0.0684 | 0.0622 | 0.7334 | 0.7591 | 0.0000 | 0.0008 | 0.0005 | 0.0014 | 0.0036 | 0.0028 | 0.0137 | 0.0194 | 0.0588 | 0.0540 | 0.0975 | 0.1111 | 0.0629 | 0.0684 | 0.0890 | 0.0925 | 0.6741 | 0.6495 | 0.0002 | 0.0007 | 0.0019 | 0.0127 | 0.0514 | 0.0927 | 0.0561 | 0.0791 | 0.7052 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 608 | 285 | | 12711 | 40214 | 295.5 | 67.78 | 143.73 | 163.15 | 209 | 239 | 260 | 277 | 293 | 309 | 328 | 350 | 384 | 0.0353 | 1418 | 1.016 | 119.62 | 46.69 | 2 | 0.0271 | 344 | 0.0013 | 26.32 | 6.921 | 0.2277 | 91894.8 | 30000000 | 10200000000 | 3620000000000 | 0.4370 | 0.2187 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0043 | 0.0006 | 0.0194 | 0.0020 | 0.0643 | 0.0160 | 0.1388 | 0.0422 | 0.1306 | 0.0429 | 0.1606 | 0.0610 | 0.4809 | 0.8354 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0053 | 0.0011 | 0.0274 | 0.0105 | 0.0590 | 0.0245 | 0.0510 | 0.0194 | 0.0701 | 0.0291 | 0.7861 | 0.9154 | 0.0071 | 0.0128 | 0.0075 | 0.0192 | 0.0179 | 0.0417 | 0.0613 | 0.1330 | 0.1289 | 0.1875 | 0.1811 | 0.2051 | 0.1097 | 0.0865 | 0.1506 | 0.1330 | 0.3358 | 0.1811 | 0.0008 | 0.0024 | 0.0064 | 0.0265 | 0.0750 | 0.1260 | 0.1010 | 0.1299 | 0.5321 | 11 | 17 | 28 | 49 | 80 | 122 | 178 | 254 | 371 | 0.0435 | 17.85 | 5.232 | 0.4864 | 47276.4 | 22300000 | 13100000000 | 8910000000000 | 0.4347 | 0.1843 | 0.0559 | 0.0013 | 0.1725 | 0.0173 | 0.2681 | 0.1183 | 0.1475 | 0.1465 | 0.1431 | 0.1771 | 0.0944 | 0.1809 | 0.0533 | 0.1241 | 0.0376 | 0.1058 | 0.0276 | 0.1288 | 0.0001 | 0.0001 | 0.0004 | 0.0006 | 0.0019 | 0.0015 | 0.0116 | 0.0097 | 0.0649 | 0.0509 | 0.1109 | 0.0898 | 0.0752 | 0.0672 | 0.1098 | 0.0956 | 0.6253 | 0.6846 | 0.0006 | 0.0007 | 0.0011 | 0.0013 | 0.0036 | 0.0075 | 0.0213 | 0.0276 | 0.0840 | 0.0988 | 0.1417 | 0.1531 | 0.0910 | 0.0952 | 0.1254 | 0.1330 | 0.5313 | 0.4828 | 0.0003 | 0.0013 | 0.0032 | 0.0164 | 0.0787 | 0.1225 | 0.0861 | 0.1208 | 0.5707 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 724 | | 2796 | 6922 | 1289.3 | 297.81 | 11.57 | 14.75 | 882 | 996 | 1126 | 1218 | 1314 | 1409 | 1473 | 1547 | 1666 | 0.1000 | 692 | 0.449 | 77.06 | 17.03 | 1 | 0.0898 | 251 | 0.0006 | 162.50 | 7.490 | 0.1405 | 1750000.0 | 2480000000 | 3640000000000 | 5.5E+15 | 0.4200 | 0.2151 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0006 | 0.0000 | 0.0150 | 0.0008 | 0.0807 | 0.0218 | 0.1502 | 0.0514 | 0.1120 | 0.0327 | 0.1352 | 0.0510 | 0.5063 | 0.8419 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0004 | 0.0334 | 0.0184 | 0.0621 | 0.0376 | 0.0375 | 0.0192 | 0.0570 | 0.0289 | 0.8086 | 0.8955 | 0.0036 | 0.0000 | 0.0125 | 0.0215 | 0.0179 | 0.0538 | 0.0339 | 0.1075 | 0.1179 | 0.1720 | 0.1732 | 0.2151 | 0.0875 | 0.1183 | 0.1304 | 0.1720 | 0.4232 | 0.1398 | 0.0000 | 0.0000 | 0.0007 | 0.0061 | 0.0509 | 0.1141 | 0.0645 | 0.0971 | 0.6667 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 16 | 0.1442 | 0.50 | 1.438 | 0.5109 | 351.5 | 25544.2 | 2750000 | 377000000 | 0.5711 | 0.1027 | 0.1170 | 0.0291 | 0.1623 | 0.0624 | 0.1857 | 0.0979 | 0.1798 | 0.1155 | 0.1535 | 0.1440 | 0.0892 | 0.1715 | 0.0738 | 0.1552 | 0.0322 | 0.1366 | 0.0066 | 0.0877 | 0.0708 | 0.0240 | 0.0893 | 0.0506 | 0.0777 | 0.0776 | 0.0796 | 0.0886 | 0.0949 | 0.1002 | 0.0888 | 0.1140 | 0.1000 | 0.1166 | 0.1124 | 0.1369 | 0.2864 | 0.2915 | 0.0290 | 0.0090 | 0.0139 | 0.0030 | 0.0189 | 0.0060 | 0.0391 | 0.0571 | 0.1009 | 0.1141 | 0.1072 | 0.1096 | 0.0971 | 0.1096 | 0.1299 | 0.1276 | 0.4641 | 0.4640 | 0.0730 | 0.0589 | 0.0518 | 0.0754 | 0.0761 | 0.0934 | 0.1013 | 0.0879 | 0.3823 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1167 | 689 | | 6111 | 11010 | 86.5 | 25.63 | 194.11 | 227.36 | 55 | 64 | 71 | 78 | 84 | 91 | 98 | 107 | 121 | 0.0750 | 826 | 0.733 | 215.47 | 54.20 | 4 | 0.0928 | 567 | 0.0034 | 11.76 | 5.994 | 0.3193 | 8137.3 | 828575 | 90900000 | 10700000000 | 0.4313 | 0.2183 | 0.0010 | 0.0004 | 0.0045 | 0.0006 | 0.0156 | 0.0018 | 0.0448 | 0.0075 | 0.1171 | 0.0342 | 0.1801 | 0.0744 | 0.1674 | 0.0795 | 0.1944 | 0.1213 | 0.2751 | 0.6804 | 0.0004 | 0.0004 | 0.0011 | 0.0000 | 0.0033 | 0.0004 | 0.0100 | 0.0028 | 0.0462 | 0.0179 | 0.0736 | 0.0369 | 0.0694 | 0.0341 | 0.1040 | 0.0529 | 0.6918 | 0.8547 | 0.0057 | 0.0065 | 0.0086 | 0.0161 | 0.0179 | 0.0581 | 0.0622 | 0.1113 | 0.1237 | 0.1597 | 0.1587 | 0.1968 | 0.1244 | 0.1323 | 0.1494 | 0.1419 | 0.3495 | 0.1774 | 0.0020 | 0.0037 | 0.0116 | 0.0317 | 0.0810 | 0.1161 | 0.1045 | 0.1324 | 0.5170 | 14 | 18 | 27 | 51 | 94 | 159 | 248 | 359 | 533 | 0.0198 | 121.90 | 6.448 | 0.3047 | 89366.6 | 55800000 | 41100000000 | 34000000000000 | 0.4757 | 0.1749 | 0.0822 | 0.0030 | 0.2716 | 0.0287 | 0.3153 | 0.2000 | 0.1093 | 0.1713 | 0.1103 | 0.1866 | 0.0562 | 0.1683 | 0.0416 | 0.0896 | 0.0083 | 0.0733 | 0.0052 | 0.0792 | 0.0007 | 0.0002 | 0.0002 | 0.0008 | 0.0034 | 0.0016 | 0.0104 | 0.0093 | 0.0707 | 0.0599 | 0.1227 | 0.1136 | 0.0860 | 0.0717 | 0.1146 | 0.1087 | 0.5914 | 0.6343 | 0.0006 | 0.0007 | 0.0014 | 0.0039 | 0.0046 | 0.0079 | 0.0149 | 0.0201 | 0.0879 | 0.0911 | 0.1479 | 0.1601 | 0.0948 | 0.0999 | 0.1390 | 0.1443 | 0.5088 | 0.4721 | 0.0003 | 0.0018 | 0.0059 | 0.0132 | 0.0749 | 0.1391 | 0.0892 | 0.1302 | 0.5455 |