High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1069 | 181 | 1596 | 20629 | 124.5 | 28.67 | 72.87 | 146.49 | 98 | 102 | 107 | 111 | 116 | 122 | 130 | 143 | 162 | 0.0438 | 904 | 0.809 | 207.96 | 60.42 | 1 | 0.3440 | 549 | 0.0093 | 6.72 | 5.134 | 0.4357 | 16321.0 | 2270000 | 339000000 | 54100000000 | 0.4382 | 0.2050 | 0.0064 | 0.0000 | 0.0064 | 0.0000 | 0.0091 | 0.0000 | 0.0246 | 0.0027 | 0.0665 | 0.0317 | 0.0938 | 0.0661 | 0.1084 | 0.0465 | 0.1321 | 0.0715 | 0.5528 | 0.7815 | 0.0051 | 0.0000 | 0.0044 | 0.0000 | 0.0066 | 0.0000 | 0.0139 | 0.0025 | 0.0285 | 0.0257 | 0.0446 | 0.0426 | 0.0599 | 0.0238 | 0.0833 | 0.0401 | 0.7538 | 0.8653 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0111 | 0.0000 | 0.0406 | 0.0000 | 0.1144 | 0.0000 | 0.1476 | 0.0000 | 0.1144 | 0.0000 | 0.1255 | 0.0000 | 0.4428 | 0.0000 | 0.0016 | 0.0081 | 0.0049 | 0.0357 | 0.0535 | 0.1086 | 0.0729 | 0.1135 | 0.6013 | 7 | 9 | 11 | 12 | 13 | 15 | 19 | 61 | 281 | 0.2995 | 21.07 | 3.063 | 0.7088 | 26767.6 | 14200000 | 8950000000 | 6390000000000 | 0.3754 | 0.2426 | 0.1380 | 0.0048 | 0.3646 | 0.0530 | 0.2760 | 0.2133 | 0.1250 | 0.2337 | 0.0781 | 0.2422 | 0.0156 | 0.1627 | 0.0026 | 0.0590 | 0.0000 | 0.0217 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0005 | 0.0062 | 0.0050 | 0.0345 | 0.0311 | 0.0536 | 0.0493 | 0.0409 | 0.0369 | 0.0551 | 0.0516 | 0.8092 | 0.8256 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0018 | 0.0030 | 0.0082 | 0.0075 | 0.0356 | 0.0413 | 0.0757 | 0.0865 | 0.0522 | 0.0543 | 0.0707 | 0.0848 | 0.7559 | 0.7221 | 0.0000 | 0.0003 | 0.0008 | 0.0058 | 0.0340 | 0.0678 | 0.0421 | 0.0646 | 0.7846 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1049 | 621 | 590 | 4448 | 85.8 | 21.32 | 144.11 | 133.60 | 56 | 64 | 73 | 81 | 87 | 93 | 99 | 106 | 114 | 0.1034 | 460 | 0.497 | 89.47 | 17.12 | 2 | 0.4254 | 251 | 0.0059 | 8.91 | 5.340 | 0.3127 | 7819.9 | 748619 | 74600000 | 7680000000 | 0.5406 | 0.1228 | 0.0066 | 0.0000 | 0.0197 | 0.0037 | 0.0656 | 0.0019 | 0.1016 | 0.0335 | 0.1311 | 0.0764 | 0.2557 | 0.1676 | 0.1213 | 0.0950 | 0.1279 | 0.1639 | 0.1705 | 0.4581 | 0.0000 | 0.0000 | 0.0023 | 0.0018 | 0.0023 | 0.0018 | 0.0227 | 0.0161 | 0.0975 | 0.0698 | 0.2245 | 0.1592 | 0.0998 | 0.0823 | 0.1678 | 0.1485 | 0.3832 | 0.5206 | 0.0000 | 0.0000 | 0.0074 | 0.0909 | 0.0662 | 0.1818 | 0.1103 | 0.2273 | 0.1838 | 0.3636 | 0.2721 | 0.0455 | 0.1176 | 0.0909 | 0.0809 | 0.0000 | 0.1618 | 0.0000 | 0.0032 | 0.0130 | 0.0260 | 0.0747 | 0.1494 | 0.1851 | 0.1071 | 0.1558 | 0.2857 | 25 | 39 | 55 | 74 | 98 | 130 | 170 | 228 | 340 | 0.0100 | 16.93 | 5.669 | 0.4305 | 38612.5 | 14500000 | 6620000000 | 3390000000000 | 0.5378 | 0.1265 | 0.0156 | 0.0023 | 0.0845 | 0.0068 | 0.1831 | 0.0288 | 0.1815 | 0.0788 | 0.1800 | 0.1455 | 0.1315 | 0.1856 | 0.0767 | 0.1667 | 0.0610 | 0.1439 | 0.0861 | 0.2417 | 0.0010 | 0.0013 | 0.0036 | 0.0025 | 0.0051 | 0.0033 | 0.0159 | 0.0134 | 0.0568 | 0.0473 | 0.0967 | 0.0854 | 0.0747 | 0.0703 | 0.0988 | 0.1000 | 0.6474 | 0.6766 | 0.0000 | 0.0037 | 0.0038 | 0.0019 | 0.0198 | 0.0131 | 0.0243 | 0.0411 | 0.0654 | 0.0626 | 0.1209 | 0.1280 | 0.0928 | 0.0888 | 0.1042 | 0.1271 | 0.5688 | 0.5336 | 0.0006 | 0.0000 | 0.0112 | 0.0262 | 0.0611 | 0.1185 | 0.0855 | 0.1017 | 0.5951 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 477 | 785 | 2057 | 7126 | 15.8 | 5.35 | 5.58 | 1.94 | 10 | 11 | 13 | 14 | 15 | 16 | 18 | 20 | 22 | 0.1343 | 957 | 1.077 | 39.62 | 14.00 | 0 | 0.0501 | 103 | 0.0083 | 6.76 | 5.098 | 0.3940 | 278.8 | 5536.95 | 125712 | 3300000 | 0.3803 | 0.2578 | 0.0068 | 0.0000 | 0.0241 | 0.0017 | 0.0395 | 0.0081 | 0.0656 | 0.0237 | 0.1070 | 0.0317 | 0.1466 | 0.0531 | 0.1688 | 0.1073 | 0.2054 | 0.1604 | 0.2363 | 0.6140 | 0.0048 | 0.0000 | 0.0131 | 0.0010 | 0.0220 | 0.0068 | 0.0275 | 0.0167 | 0.0440 | 0.0256 | 0.0557 | 0.0329 | 0.0688 | 0.0605 | 0.0922 | 0.0924 | 0.6717 | 0.7641 | 0.0168 | 0.0437 | 0.0216 | 0.0437 | 0.0481 | 0.0328 | 0.0793 | 0.0656 | 0.0865 | 0.1038 | 0.1346 | 0.1093 | 0.1298 | 0.0710 | 0.1394 | 0.1749 | 0.3438 | 0.3552 | 0.0178 | 0.0231 | 0.0241 | 0.0409 | 0.0409 | 0.0682 | 0.0860 | 0.1091 | 0.5897 | 3 | 4 | 5 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0254 | 8.33 | 4.093 | 0.3635 | 34.9 | 237.89 | 1743 | 13611.8 | 0.5441 | 0.1416 | 0.0029 | 0.0002 | 0.0262 | 0.0017 | 0.0867 | 0.0113 | 0.1633 | 0.0354 | 0.2318 | 0.0789 | 0.2315 | 0.1447 | 0.1584 | 0.2575 | 0.0821 | 0.2968 | 0.0170 | 0.1734 | 0.0004 | 0.0002 | 0.0045 | 0.0006 | 0.0189 | 0.0043 | 0.0680 | 0.0220 | 0.1231 | 0.0509 | 0.2194 | 0.0876 | 0.2719 | 0.1709 | 0.2172 | 0.3403 | 0.0767 | 0.3232 | 0.2384 | 0.4990 | 0.3216 | 0.3638 | 0.2659 | 0.1113 | 0.1235 | 0.0258 | 0.0369 | 0.0000 | 0.0129 | 0.0000 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0115 | 0.0662 | 0.1649 | 0.2477 | 0.2359 | 0.1587 | 0.0825 | 0.0266 | 0.0059 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1156 | 346 | 318 | 920 | 14.3 | 4.68 | 5.30 | 2.36 | 9 | 10 | 12 | 13 | 14 | 14 | 16 | 17 | 21 | 0.2957 | 272 | 1.375 | 23.54 | 9.49 | 0 | 0.1855 | 59 | 0.0096 | 15.54 | 4.861 | 0.2753 | 224.9 | 3921.78 | 75133.4 | 1570000 | 0.3709 | 0.2571 | 0.0068 | 0.0000 | 0.0608 | 0.0000 | 0.0541 | 0.0000 | 0.1689 | 0.0498 | 0.2365 | 0.0805 | 0.1419 | 0.0958 | 0.1824 | 0.1149 | 0.1149 | 0.2835 | 0.0338 | 0.3755 | 0.0000 | 0.0000 | 0.0177 | 0.0000 | 0.0044 | 0.0000 | 0.0354 | 0.0301 | 0.1150 | 0.0569 | 0.0885 | 0.0535 | 0.1726 | 0.0635 | 0.1770 | 0.1639 | 0.3894 | 0.6321 | 0.0128 | 0.0789 | 0.0513 | 0.0526 | 0.0641 | 0.0263 | 0.0641 | 0.0526 | 0.1154 | 0.1842 | 0.1667 | 0.0789 | 0.1667 | 0.1579 | 0.1795 | 0.1842 | 0.1795 | 0.1842 | 0.0000 | 0.0248 | 0.0745 | 0.1056 | 0.1242 | 0.1242 | 0.1553 | 0.1553 | 0.2360 | 3 | 3 | 5 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0283 | 11.90 | 3.904 | 0.3091 | 33.7 | 240.012 | 1881.41 | 15989.2 | 0.5312 | 0.1181 | 0.1609 | 0.0033 | 0.2913 | 0.0384 | 0.3000 | 0.0801 | 0.1913 | 0.1436 | 0.0522 | 0.2053 | 0.0043 | 0.2354 | 0.0000 | 0.1803 | 0.0000 | 0.0835 | 0.0000 | 0.0301 | 0.0000 | 0.0000 | 0.0124 | 0.0000 | 0.0495 | 0.0132 | 0.1533 | 0.0444 | 0.2059 | 0.1187 | 0.2384 | 0.1007 | 0.2043 | 0.1775 | 0.1130 | 0.2818 | 0.0232 | 0.2638 | 0.0240 | 0.1277 | 0.0962 | 0.2681 | 0.2308 | 0.2766 | 0.2837 | 0.2383 | 0.2139 | 0.0766 | 0.1106 | 0.0128 | 0.0313 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0124 | 0.0496 | 0.1597 | 0.2031 | 0.2357 | 0.2031 | 0.1132 | 0.0233 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 771 | 729 | 699 | 8074 | 51.0 | 15.12 | 134.99 | 188.23 | 31 | 35 | 40 | 45 | 50 | 56 | 62 | 67 | 72 | 0.0588 | 475 | 1.025 | 40.01 | 10.20 | 1 | 0.1373 | 96 | 0.0059 | 6.82 | 5.319 | 0.3605 | 2826.1 | 167621 | 10500000 | 678000000 | 0.3593 | 0.2671 | 0.0074 | 0.0000 | 0.0223 | 0.0106 | 0.0186 | 0.0195 | 0.0483 | 0.0283 | 0.1264 | 0.0496 | 0.1561 | 0.0637 | 0.1822 | 0.0991 | 0.2119 | 0.1558 | 0.2268 | 0.5735 | 0.0000 | 0.0000 | 0.0021 | 0.0016 | 0.0021 | 0.0094 | 0.0125 | 0.0141 | 0.0480 | 0.0297 | 0.0438 | 0.0375 | 0.0438 | 0.0531 | 0.0710 | 0.0688 | 0.7766 | 0.7859 | 0.0000 | 0.0267 | 0.0095 | 0.0533 | 0.0095 | 0.0533 | 0.0714 | 0.1867 | 0.0571 | 0.1333 | 0.0857 | 0.2000 | 0.1333 | 0.1733 | 0.1762 | 0.1467 | 0.4571 | 0.0267 | 0.0000 | 0.0029 | 0.0086 | 0.0201 | 0.0430 | 0.0630 | 0.0516 | 0.0860 | 0.7249 | 17 | 20 | 22 | 27 | 42 | 69 | 121 | 231 | 414 | 0.1036 | 10.05 | 4.238 | 0.6273 | 53649.5 | 30800000 | 20700000000 | 15500000000000 | 0.6068 | 0.0942 | 0.0493 | 0.0037 | 0.1637 | 0.0266 | 0.2249 | 0.1322 | 0.1657 | 0.1506 | 0.1400 | 0.1304 | 0.1183 | 0.1680 | 0.0552 | 0.1074 | 0.0414 | 0.0973 | 0.0414 | 0.1837 | 0.0004 | 0.0007 | 0.0012 | 0.0013 | 0.0046 | 0.0030 | 0.0150 | 0.0167 | 0.0547 | 0.0407 | 0.0875 | 0.0781 | 0.0586 | 0.0524 | 0.0848 | 0.0851 | 0.6933 | 0.7219 | 0.0005 | 0.0005 | 0.0019 | 0.0042 | 0.0043 | 0.0100 | 0.0168 | 0.0173 | 0.0570 | 0.0614 | 0.1049 | 0.0992 | 0.0608 | 0.0719 | 0.0967 | 0.1028 | 0.6571 | 0.6327 | 0.0000 | 0.0039 | 0.0035 | 0.0195 | 0.0500 | 0.0925 | 0.0626 | 0.0947 | 0.6733 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 372 | 139 | 4417 | 11190 | 35.9 | 14.42 | 6.81 | 2.68 | 18 | 23 | 27 | 31 | 35 | 38 | 42 | 47 | 55 | 0.1108 | 1240 | 0.972 | 96.52 | 27.73 | 0 | 0.0541 | 239 | 0.0016 | 19.80 | 6.657 | 0.2399 | 1496.0 | 70708.7 | 3720000 | 215000000 | 0.3566 | 0.2612 | 0.0074 | 0.0033 | 0.0138 | 0.0046 | 0.0275 | 0.0100 | 0.0401 | 0.0219 | 0.0682 | 0.0306 | 0.1181 | 0.0604 | 0.1456 | 0.0764 | 0.2189 | 0.1249 | 0.3605 | 0.6679 | 0.0027 | 0.0016 | 0.0044 | 0.0025 | 0.0061 | 0.0041 | 0.0123 | 0.0106 | 0.0194 | 0.0144 | 0.0310 | 0.0289 | 0.0358 | 0.0324 | 0.0607 | 0.0501 | 0.8275 | 0.8554 | 0.0135 | 0.0136 | 0.0143 | 0.0303 | 0.0236 | 0.0394 | 0.0412 | 0.0455 | 0.0648 | 0.0636 | 0.0732 | 0.0924 | 0.0875 | 0.1030 | 0.1052 | 0.1288 | 0.5766 | 0.4833 | 0.0024 | 0.0118 | 0.0142 | 0.0217 | 0.0307 | 0.0558 | 0.0728 | 0.1281 | 0.6626 | 3 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0130 | 14.88 | 4.690 | 0.2835 | 53.5 | 466.389 | 4418.91 | 44994.1 | 0.5386 | 0.1220 | 0.0193 | 0.0018 | 0.0771 | 0.0147 | 0.1782 | 0.0531 | 0.2352 | 0.1151 | 0.2415 | 0.1932 | 0.1553 | 0.2539 | 0.0676 | 0.2164 | 0.0219 | 0.1202 | 0.0039 | 0.0316 | 0.0009 | 0.0001 | 0.0099 | 0.0021 | 0.0376 | 0.0123 | 0.0944 | 0.0380 | 0.1707 | 0.0873 | 0.2304 | 0.1689 | 0.2167 | 0.2533 | 0.1681 | 0.2793 | 0.0711 | 0.1586 | 0.1499 | 0.2801 | 0.2687 | 0.3198 | 0.2320 | 0.2121 | 0.1617 | 0.1088 | 0.0909 | 0.0480 | 0.0568 | 0.0201 | 0.0279 | 0.0084 | 0.0099 | 0.0022 | 0.0022 | 0.0006 | 0.0072 | 0.0437 | 0.1150 | 0.1799 | 0.2208 | 0.1990 | 0.1331 | 0.0731 | 0.0283 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 844 | 2908 | 15413 | 16.0 | 5.68 | 6.17 | 2.21 | 10 | 12 | 13 | 14 | 15 | 16 | 18 | 19 | 22 | 0.0804 | 1239 | 1.278 | 24.04 | 7.81 | 0 | 0.0193 | 56 | 0.0081 | 8.98 | 5.211 | 0.3653 | 289.8 | 6020.69 | 146883 | 4220000 | 0.4199 | 0.2102 | 0.0085 | 0.0004 | 0.0216 | 0.0036 | 0.0385 | 0.0085 | 0.0745 | 0.0222 | 0.1137 | 0.0287 | 0.1476 | 0.0534 | 0.2149 | 0.0825 | 0.2097 | 0.1756 | 0.1711 | 0.6250 | 0.0052 | 0.0000 | 0.0124 | 0.0018 | 0.0204 | 0.0040 | 0.0261 | 0.0141 | 0.0461 | 0.0196 | 0.0518 | 0.0236 | 0.0969 | 0.0460 | 0.1330 | 0.0873 | 0.6081 | 0.8036 | 0.0279 | 0.0590 | 0.0540 | 0.0729 | 0.0714 | 0.0521 | 0.0976 | 0.0486 | 0.1063 | 0.0972 | 0.0871 | 0.1632 | 0.1080 | 0.1042 | 0.1307 | 0.1250 | 0.3171 | 0.2778 | 0.0127 | 0.0202 | 0.0254 | 0.0419 | 0.0538 | 0.0695 | 0.1046 | 0.1674 | 0.5045 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0174 | 10.89 | 4.353 | 0.3184 | 42.9 | 326.59 | 2675.72 | 23343.4 | 0.5105 | 0.1490 | 0.0093 | 0.0007 | 0.0467 | 0.0029 | 0.1332 | 0.0168 | 0.2261 | 0.0557 | 0.2649 | 0.1187 | 0.2015 | 0.1957 | 0.0932 | 0.2556 | 0.0225 | 0.2405 | 0.0026 | 0.1134 | 0.0005 | 0.0000 | 0.0014 | 0.0005 | 0.0117 | 0.0029 | 0.0395 | 0.0124 | 0.0975 | 0.0337 | 0.1985 | 0.0723 | 0.2678 | 0.1849 | 0.2578 | 0.3562 | 0.1253 | 0.3371 | 0.1026 | 0.2983 | 0.2437 | 0.3365 | 0.2794 | 0.2278 | 0.2269 | 0.0988 | 0.1028 | 0.0292 | 0.0369 | 0.0090 | 0.0071 | 0.0004 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0196 | 0.0575 | 0.1217 | 0.1919 | 0.2514 | 0.2092 | 0.1174 | 0.0298 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 125 | 887 | 914 | 10249 | 57.4 | 40.69 | 232.85 | 304.99 | 28 | 31 | 33 | 35 | 38 | 42 | 56 | 82 | 127 | 0.0631 | 647 | 1.229 | 27.66 | 9.43 | 1 | 0.0722 | 66 | 0.0076 | 22.99 | 5.445 | 0.3165 | 4951.9 | 588247 | 83100000 | 12800000000 | 0.3258 | 0.3035 | 0.0088 | 0.0152 | 0.0000 | 0.0127 | 0.0531 | 0.0482 | 0.1239 | 0.0736 | 0.3451 | 0.1624 | 0.2832 | 0.1574 | 0.1416 | 0.1650 | 0.0354 | 0.1421 | 0.0088 | 0.2234 | 0.0000 | 0.0103 | 0.0000 | 0.0086 | 0.0091 | 0.0325 | 0.0151 | 0.0462 | 0.0393 | 0.0856 | 0.0665 | 0.0805 | 0.0665 | 0.0702 | 0.0634 | 0.0771 | 0.7402 | 0.5890 | 0.0000 | 0.0053 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0046 | 0.0211 | 0.0826 | 0.0842 | 0.0872 | 0.0579 | 0.0459 | 0.0737 | 0.1101 | 0.0895 | 0.6697 | 0.6684 | 0.0000 | 0.0000 | 0.0037 | 0.0297 | 0.0409 | 0.0632 | 0.0743 | 0.0706 | 0.7175 | 22 | 26 | 32 | 50 | 83 | 141 | 256 | 424 | 686 | 0.0356 | 29.95 | 5.321 | 0.4926 | 147227.0 | 131000000 | 137000000000 | 161000000000000 | 0.6516 | 0.0660 | 0.0697 | 0.0026 | 0.1780 | 0.0222 | 0.2107 | 0.0941 | 0.1395 | 0.1359 | 0.1543 | 0.1737 | 0.1157 | 0.1966 | 0.0772 | 0.1261 | 0.0356 | 0.1261 | 0.0193 | 0.1228 | 0.0008 | 0.0002 | 0.0011 | 0.0012 | 0.0025 | 0.0051 | 0.0195 | 0.0177 | 0.0641 | 0.0572 | 0.0786 | 0.0824 | 0.0675 | 0.0545 | 0.0853 | 0.0863 | 0.6804 | 0.6953 | 0.0010 | 0.0015 | 0.0031 | 0.0035 | 0.0062 | 0.0073 | 0.0244 | 0.0289 | 0.0714 | 0.0763 | 0.0975 | 0.0960 | 0.0752 | 0.0867 | 0.0962 | 0.1044 | 0.6250 | 0.5954 | 0.0006 | 0.0012 | 0.0046 | 0.0178 | 0.0705 | 0.0911 | 0.0644 | 0.0929 | 0.6569 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 897 | 352 | 491 | 10165 | 31.2 | 10.66 | 5.57 | 2.04 | 21 | 23 | 24 | 26 | 27 | 30 | 34 | 40 | 49 | 0.0858 | 872 | 0.813 | 87.21 | 20.59 | 5 | 0.4073 | 200 | 0.0618 | 0.76 | 3.150 | 0.6872 | 1083.9 | 42132.6 | 1810000 | 83600000 | 0.3481 | 0.2731 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0187 | 0.0025 | 0.0561 | 0.0150 | 0.1168 | 0.0848 | 0.2336 | 0.0798 | 0.1963 | 0.0873 | 0.1869 | 0.1446 | 0.1729 | 0.5860 | 0.0061 | 0.0000 | 0.0061 | 0.0000 | 0.0122 | 0.0021 | 0.0334 | 0.0125 | 0.0608 | 0.0582 | 0.0912 | 0.0353 | 0.0821 | 0.0561 | 0.1003 | 0.0811 | 0.6079 | 0.7547 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0348 | 0.0625 | 0.0609 | 0.0500 | 0.1391 | 0.1625 | 0.0609 | 0.1125 | 0.1043 | 0.0750 | 0.6000 | 0.5375 | 0.0000 | 0.0107 | 0.0000 | 0.0481 | 0.0428 | 0.1070 | 0.0695 | 0.1016 | 0.6203 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0061 | 0.11 | 0.381 | 0.0699 | 35.2 | 247.481 | 1925.98 | 16644.2 | 0.5163 | 0.1494 | 0.0075 | 0.0004 | 0.0317 | 0.0014 | 0.1096 | 0.0083 | 0.1889 | 0.0233 | 0.2557 | 0.0515 | 0.2310 | 0.1180 | 0.1247 | 0.2326 | 0.0447 | 0.3477 | 0.0060 | 0.2168 | 0.0016 | 0.0000 | 0.0075 | 0.0002 | 0.0348 | 0.0045 | 0.0908 | 0.0154 | 0.1571 | 0.0325 | 0.2323 | 0.0692 | 0.2275 | 0.1499 | 0.1597 | 0.3269 | 0.0887 | 0.4014 | 0.2469 | 0.4372 | 0.2984 | 0.2271 | 0.1850 | 0.0804 | 0.0888 | 0.0635 | 0.0564 | 0.0536 | 0.0355 | 0.0409 | 0.0392 | 0.0381 | 0.0282 | 0.0381 | 0.0214 | 0.0212 | 0.0197 | 0.0760 | 0.1532 | 0.2101 | 0.1844 | 0.1602 | 0.1001 | 0.0600 | 0.0363 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1103 | 521 | 38572 | 41531 | 83.7 | 70.09 | 7.10 | 2.74 | 45 | 48 | 50 | 53 | 56 | 62 | 73 | 98 | 152 | 0.0457 | 1898 | 0.782 | 128.16 | 45.34 | 3 | 0.0101 | 390 | 0.0492 | 1.50 | 4.084 | 0.6882 | 11919.8 | 2870000 | 920000000 | 334000000000 | 0.4510 | 0.1895 | 0.0109 | 0.0089 | 0.0164 | 0.0172 | 0.0246 | 0.0246 | 0.0351 | 0.0389 | 0.0605 | 0.0504 | 0.0801 | 0.0590 | 0.0958 | 0.0673 | 0.1409 | 0.0885 | 0.5357 | 0.6452 | 0.0040 | 0.0067 | 0.0055 | 0.0130 | 0.0089 | 0.0188 | 0.0105 | 0.0286 | 0.0183 | 0.0354 | 0.0237 | 0.0412 | 0.0271 | 0.0468 | 0.0418 | 0.0594 | 0.8604 | 0.7500 | 0.0015 | 0.0009 | 0.0027 | 0.0019 | 0.0047 | 0.0041 | 0.0104 | 0.0090 | 0.0173 | 0.0159 | 0.0259 | 0.0282 | 0.0314 | 0.0309 | 0.0401 | 0.0398 | 0.8660 | 0.8695 | 0.0020 | 0.0024 | 0.0056 | 0.0088 | 0.0174 | 0.0214 | 0.0294 | 0.0366 | 0.8764 | 4 | 5 | 6 | 6 | 7 | 8 | 8 | 9 | 11 | 0.4747 | 0.33 | 1.180 | 0.8414 | 57.9 | 527.37 | 5295.83 | 58155.7 | 0.4995 | 0.1829 | 0.0184 | 0.0024 | 0.0723 | 0.0096 | 0.1551 | 0.0301 | 0.2242 | 0.0749 | 0.2394 | 0.1555 | 0.1742 | 0.2423 | 0.0889 | 0.2556 | 0.0251 | 0.1713 | 0.0024 | 0.0583 | 0.0022 | 0.0001 | 0.0106 | 0.0010 | 0.0291 | 0.0053 | 0.0623 | 0.0178 | 0.1060 | 0.0556 | 0.1606 | 0.1162 | 0.2066 | 0.1940 | 0.2316 | 0.2914 | 0.1910 | 0.3187 | 0.0905 | 0.1632 | 0.1612 | 0.2060 | 0.1796 | 0.1882 | 0.1754 | 0.1469 | 0.1412 | 0.1102 | 0.1007 | 0.0685 | 0.0624 | 0.0461 | 0.0489 | 0.0412 | 0.0401 | 0.0296 | 0.0110 | 0.0392 | 0.0830 | 0.1233 | 0.1517 | 0.1724 | 0.1677 | 0.1502 | 0.1015 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 762 | 189 | 1376 | 10419 | 35.3 | 9.21 | 10.27 | 5.63 | 22 | 26 | 29 | 33 | 36 | 39 | 42 | 44 | 47 | 0.0696 | 725 | 0.931 | 32.02 | 6.00 | 6 | 0.0509 | 70 | 0.0514 | 0.71 | 3.174 | 0.7185 | 1329.9 | 52792.9 | 2180000 | 92900000 | 0.3888 | 0.2401 | 0.0112 | 0.0000 | 0.0224 | 0.0000 | 0.0384 | 0.0041 | 0.0480 | 0.0132 | 0.0880 | 0.0438 | 0.1296 | 0.0661 | 0.1552 | 0.0867 | 0.2224 | 0.1189 | 0.2848 | 0.6672 | 0.0038 | 0.0000 | 0.0029 | 0.0000 | 0.0105 | 0.0023 | 0.0134 | 0.0077 | 0.0335 | 0.0302 | 0.0374 | 0.0294 | 0.0412 | 0.0394 | 0.0766 | 0.0510 | 0.7807 | 0.8399 | 0.0167 | 0.0854 | 0.0143 | 0.1707 | 0.0263 | 0.1341 | 0.0430 | 0.2073 | 0.0740 | 0.1463 | 0.0883 | 0.2073 | 0.0931 | 0.0244 | 0.1551 | 0.0244 | 0.4893 | 0.0000 | 0.0027 | 0.0040 | 0.0121 | 0.0214 | 0.0429 | 0.0402 | 0.0657 | 0.0979 | 0.7131 | 5 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 15 | 0.2596 | 0.30 | 0.975 | 0.6174 | 137.1 | 3359.17 | 189453 | 16100000 | 0.5305 | 0.1486 | 0.0352 | 0.0019 | 0.0945 | 0.0122 | 0.1668 | 0.0289 | 0.2222 | 0.0571 | 0.2112 | 0.0964 | 0.1536 | 0.1503 | 0.0877 | 0.2161 | 0.0244 | 0.2552 | 0.0044 | 0.1819 | 0.0068 | 0.0000 | 0.0230 | 0.0021 | 0.0437 | 0.0082 | 0.0549 | 0.0212 | 0.0735 | 0.0449 | 0.0787 | 0.0675 | 0.1107 | 0.0939 | 0.1744 | 0.1513 | 0.4343 | 0.6109 | 0.0472 | 0.0923 | 0.0513 | 0.1077 | 0.0808 | 0.1294 | 0.1073 | 0.1464 | 0.1292 | 0.1422 | 0.1429 | 0.1316 | 0.1703 | 0.1167 | 0.1551 | 0.0716 | 0.1158 | 0.0621 | 0.0303 | 0.0432 | 0.0455 | 0.0586 | 0.0760 | 0.1103 | 0.1403 | 0.2192 | 0.2767 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 439 | 9462 | 17615 | 66.2 | 18.80 | 11.63 | 7.94 | 45 | 48 | 51 | 57 | 63 | 69 | 76 | 85 | 93 | 0.0582 | 1025 | 0.806 | 93.06 | 26.68 | 0 | 0.0260 | 246 | 0.0396 | 0.80 | 3.627 | 0.7208 | 4738.0 | 364637 | 29900000 | 2590000000 | 0.4090 | 0.2322 | 0.0114 | 0.0009 | 0.0137 | 0.0014 | 0.0190 | 0.0032 | 0.0307 | 0.0089 | 0.0497 | 0.0193 | 0.0678 | 0.0417 | 0.0898 | 0.0415 | 0.1269 | 0.0742 | 0.5909 | 0.8088 | 0.0052 | 0.0000 | 0.0064 | 0.0002 | 0.0081 | 0.0003 | 0.0109 | 0.0024 | 0.0165 | 0.0081 | 0.0215 | 0.0205 | 0.0284 | 0.0132 | 0.0370 | 0.0319 | 0.8659 | 0.9234 | 0.0061 | 0.0140 | 0.0065 | 0.0220 | 0.0105 | 0.0451 | 0.0252 | 0.0762 | 0.0304 | 0.1062 | 0.0527 | 0.1333 | 0.0641 | 0.1283 | 0.0933 | 0.1413 | 0.7112 | 0.3337 | 0.0026 | 0.0049 | 0.0086 | 0.0123 | 0.0283 | 0.0339 | 0.0416 | 0.0706 | 0.7972 | 5 | 6 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 0.2867 | 0.33 | 1.922 | 0.8442 | 198.3 | 4862.52 | 154893 | 5820000 | 0.5138 | 0.1400 | 0.0871 | 0.0128 | 0.1401 | 0.0280 | 0.1505 | 0.0586 | 0.1491 | 0.0912 | 0.1521 | 0.1375 | 0.1294 | 0.1665 | 0.1167 | 0.1770 | 0.0606 | 0.1781 | 0.0146 | 0.1503 | 0.0408 | 0.0059 | 0.0668 | 0.0174 | 0.0671 | 0.0381 | 0.0575 | 0.0614 | 0.0582 | 0.0937 | 0.0540 | 0.1156 | 0.0645 | 0.1142 | 0.0925 | 0.1136 | 0.4986 | 0.4402 | 0.0246 | 0.0157 | 0.0222 | 0.0242 | 0.0309 | 0.0310 | 0.0415 | 0.0336 | 0.0492 | 0.0529 | 0.0632 | 0.0663 | 0.0719 | 0.0777 | 0.1169 | 0.1326 | 0.5796 | 0.5660 | 0.0564 | 0.0389 | 0.0353 | 0.0306 | 0.0484 | 0.0603 | 0.0728 | 0.0984 | 0.5589 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1201 | 147 | 25401 | 21792 | 80.3 | 36.47 | 7.79 | 3.16 | 47 | 51 | 55 | 60 | 67 | 79 | 95 | 111 | 130 | 0.0646 | 1407 | 0.643 | 109.48 | 22.02 | 3 | 0.0122 | 311 | 0.0238 | 1.54 | 4.339 | 0.6433 | 7784.7 | 930349 | 141000000 | 27400000000 | 0.3746 | 0.2574 | 0.0183 | 0.0041 | 0.0285 | 0.0101 | 0.0332 | 0.0165 | 0.0445 | 0.0216 | 0.0579 | 0.0307 | 0.0760 | 0.0454 | 0.0991 | 0.0645 | 0.1547 | 0.1011 | 0.4878 | 0.7059 | 0.0063 | 0.0025 | 0.0088 | 0.0051 | 0.0101 | 0.0093 | 0.0128 | 0.0127 | 0.0158 | 0.0171 | 0.0202 | 0.0254 | 0.0263 | 0.0353 | 0.0450 | 0.0545 | 0.8547 | 0.8381 | 0.0029 | 0.0096 | 0.0051 | 0.0076 | 0.0087 | 0.0135 | 0.0154 | 0.0237 | 0.0181 | 0.0317 | 0.0252 | 0.0416 | 0.0356 | 0.0590 | 0.0614 | 0.0833 | 0.8277 | 0.7300 | 0.0039 | 0.0045 | 0.0066 | 0.0106 | 0.0121 | 0.0194 | 0.0250 | 0.0402 | 0.8777 | 4 | 5 | 6 | 7 | 8 | 9 | 9 | 10 | 12 | 0.3288 | 0.54 | 1.489 | 0.7679 | 70.7 | 710.738 | 7758.34 | 90867.1 | 0.5651 | 0.1468 | 0.0276 | 0.0002 | 0.1012 | 0.0027 | 0.1830 | 0.0162 | 0.2395 | 0.0448 | 0.2232 | 0.1065 | 0.1440 | 0.1983 | 0.0622 | 0.2724 | 0.0175 | 0.2494 | 0.0018 | 0.1095 | 0.0011 | 0.0001 | 0.0095 | 0.0007 | 0.0313 | 0.0047 | 0.0743 | 0.0148 | 0.1392 | 0.0405 | 0.2209 | 0.1002 | 0.2544 | 0.1989 | 0.1985 | 0.3291 | 0.0707 | 0.3109 | 0.0837 | 0.3817 | 0.2220 | 0.3524 | 0.2715 | 0.1695 | 0.2102 | 0.0699 | 0.1317 | 0.0232 | 0.0547 | 0.0028 | 0.0218 | 0.0004 | 0.0035 | 0.0000 | 0.0010 | 0.0000 | 0.0061 | 0.0422 | 0.1149 | 0.1974 | 0.2403 | 0.2128 | 0.1308 | 0.0484 | 0.0072 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 559 | 386 | 734 | 10113 | 39.1 | 16.71 | 545.35 | 386.84 | 28 | 29 | 30 | 31 | 32 | 34 | 37 | 45 | 64 | 0.0518 | 524 | 0.593 | 209.07 | 60.01 | 2 | 0.9973 | 732 | 0.0308 | 4.90 | 4.259 | 0.5054 | 1809.2 | 103002 | 7120000 | 567000000 | 0.4029 | 0.2328 | 0.0252 | 0.0000 | 0.0540 | 0.0000 | 0.0755 | 0.0000 | 0.1295 | 0.0174 | 0.1403 | 0.0616 | 0.1799 | 0.0585 | 0.1403 | 0.0932 | 0.1475 | 0.0853 | 0.1079 | 0.6840 | 0.0170 | 0.0000 | 0.0365 | 0.0000 | 0.0462 | 0.0000 | 0.0754 | 0.0136 | 0.0730 | 0.0409 | 0.0900 | 0.0368 | 0.0681 | 0.0587 | 0.1095 | 0.0559 | 0.4842 | 0.7940 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0376 | 0.0200 | 0.0752 | 0.1500 | 0.0827 | 0.0400 | 0.0977 | 0.1100 | 0.0752 | 0.1200 | 0.6316 | 0.5600 | 0.0000 | 0.0052 | 0.0103 | 0.0155 | 0.0619 | 0.0825 | 0.0825 | 0.0928 | 0.6495 | 110 | 186 | 267 | 361 | 473 | 591 | 720 | 874 | 1078 | 0.0014 | 42.72 | 7.230 | 0.2482 | 447031.0 | 456000000 | 536000000000 | 698000000000000 | 0.4409 | 0.2151 | 0.0049 | 0.0008 | 0.0213 | 0.0030 | 0.1079 | 0.0134 | 0.1706 | 0.0422 | 0.2262 | 0.1218 | 0.2011 | 0.1874 | 0.1226 | 0.1487 | 0.0823 | 0.1769 | 0.0632 | 0.3059 | 0.0004 | 0.0003 | 0.0013 | 0.0006 | 0.0037 | 0.0034 | 0.0144 | 0.0101 | 0.0397 | 0.0346 | 0.0744 | 0.0570 | 0.0498 | 0.0461 | 0.0699 | 0.0684 | 0.7464 | 0.7795 | 0.0017 | 0.0015 | 0.0017 | 0.0015 | 0.0043 | 0.0070 | 0.0218 | 0.0278 | 0.0519 | 0.0725 | 0.0930 | 0.1147 | 0.0904 | 0.1118 | 0.1106 | 0.1336 | 0.6246 | 0.5296 | 0.0007 | 0.0052 | 0.0059 | 0.0197 | 0.0437 | 0.0749 | 0.0656 | 0.0837 | 0.7007 |