High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 424 | 598 | | 10118 | 27401 | 44.6 | 15.32 | 9.66 | 10.14 | 26 | 30 | 34 | 39 | 43 | 46 | 51 | 58 | 68 | 0.0697 | 1910 | 0.653 | 52.00 | 10.05 | 2 | 0.0153 | 155 | 0.0320 | 0.80 | 3.734 | 0.7116 | 2220.7 | 121956 | 7260000 | 460000000 | 0.4370 | 0.1928 | 0.0033 | 0.0009 | 0.0117 | 0.0021 | 0.0212 | 0.0062 | 0.0405 | 0.0162 | 0.0660 | 0.0337 | 0.0944 | 0.0462 | 0.1215 | 0.0617 | 0.1775 | 0.0854 | 0.4639 | 0.7475 | 0.0012 | 0.0004 | 0.0041 | 0.0011 | 0.0082 | 0.0029 | 0.0150 | 0.0080 | 0.0223 | 0.0197 | 0.0297 | 0.0256 | 0.0429 | 0.0335 | 0.0634 | 0.0478 | 0.8132 | 0.8611 | 0.0054 | 0.0041 | 0.0122 | 0.0117 | 0.0168 | 0.0233 | 0.0337 | 0.0425 | 0.0471 | 0.0487 | 0.0631 | 0.0720 | 0.0608 | 0.0822 | 0.0838 | 0.0864 | 0.6771 | 0.6292 | 0.0039 | 0.0100 | 0.0142 | 0.0234 | 0.0345 | 0.0395 | 0.0542 | 0.0860 | 0.7342 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 11 | 16 | 0.0607 | 0.27 | 1.084 | 0.3393 | 196.2 | 10715.8 | 1130000 | 163000000 | 0.5653 | 0.1216 | 0.0777 | 0.0043 | 0.1202 | 0.0147 | 0.1403 | 0.0416 | 0.1602 | 0.0819 | 0.1662 | 0.1200 | 0.1599 | 0.1529 | 0.1160 | 0.1781 | 0.0486 | 0.2087 | 0.0109 | 0.1979 | 0.0433 | 0.0019 | 0.0675 | 0.0095 | 0.0728 | 0.0304 | 0.0744 | 0.0626 | 0.0830 | 0.0967 | 0.0877 | 0.1232 | 0.0996 | 0.1307 | 0.1151 | 0.1503 | 0.3566 | 0.3946 | 0.0629 | 0.0327 | 0.0480 | 0.0262 | 0.0487 | 0.0276 | 0.0411 | 0.0316 | 0.0533 | 0.0584 | 0.0696 | 0.0784 | 0.0791 | 0.0835 | 0.1064 | 0.1232 | 0.4909 | 0.5384 | 0.0684 | 0.0635 | 0.0650 | 0.0662 | 0.0726 | 0.0769 | 0.0668 | 0.0896 | 0.4311 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 875 | 62 | | 1334 | 3820 | 91.9 | 21.30 | 105.54 | 80.69 | 68 | 74 | 80 | 85 | 90 | 95 | 100 | 106 | 117 | 0.1102 | 421 | 0.866 | 95.82 | 24.17 | 1 | 0.1807 | 241 | 0.0026 | 28.10 | 6.166 | 0.2282 | 8892.5 | 911642 | 99600000 | 11700000000 | 0.4476 | 0.2105 | 0.0034 | 0.0000 | 0.0056 | 0.0000 | 0.0213 | 0.0048 | 0.0369 | 0.0081 | 0.0884 | 0.0306 | 0.1432 | 0.0564 | 0.1454 | 0.0596 | 0.1946 | 0.0854 | 0.3613 | 0.7550 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0000 | 0.0157 | 0.0023 | 0.0507 | 0.0235 | 0.1005 | 0.0454 | 0.0811 | 0.0310 | 0.1180 | 0.0613 | 0.6267 | 0.8365 | 0.0419 | 0.0125 | 0.0366 | 0.0375 | 0.0628 | 0.1000 | 0.0785 | 0.1000 | 0.1937 | 0.2125 | 0.2042 | 0.1000 | 0.0628 | 0.0750 | 0.0995 | 0.1375 | 0.2199 | 0.2250 | 0.0016 | 0.0128 | 0.0096 | 0.0465 | 0.1348 | 0.1750 | 0.1236 | 0.1637 | 0.3323 | 28 | 40 | 52 | 68 | 85 | 105 | 126 | 153 | 212 | 0.0130 | 7.64 | 5.068 | 0.4624 | 17649.0 | 4150000 | 1240000000 | 442000000000 | 0.4801 | 0.1727 | 0.0158 | 0.0013 | 0.0706 | 0.0076 | 0.1364 | 0.0297 | 0.1583 | 0.0607 | 0.1754 | 0.1208 | 0.1851 | 0.1720 | 0.1218 | 0.1562 | 0.0938 | 0.1720 | 0.0426 | 0.2796 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0067 | 0.0050 | 0.0249 | 0.0184 | 0.0716 | 0.0537 | 0.1095 | 0.0910 | 0.0851 | 0.0746 | 0.1183 | 0.1065 | 0.5817 | 0.6491 | 0.0036 | 0.0062 | 0.0099 | 0.0075 | 0.0172 | 0.0249 | 0.0506 | 0.0634 | 0.1112 | 0.1045 | 0.1546 | 0.1505 | 0.1103 | 0.1256 | 0.1338 | 0.1381 | 0.4087 | 0.3794 | 0.0013 | 0.0072 | 0.0118 | 0.0301 | 0.0740 | 0.1382 | 0.0950 | 0.1434 | 0.4990 |
| SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 451 | | 11232 | 18145 | 198.9 | 80.62 | 6.13 | 2.92 | 96 | 118 | 138 | 163 | 190 | 224 | 254 | 281 | 308 | 0.0881 | 1598 | 0.402 | 135.09 | 20.03 | 6 | 0.0363 | 408 | 0.0017 | 7.54 | 6.630 | 0.3605 | 46068.3 | 11900000 | 3280000000 | 953000000000 | 0.4257 | 0.1921 | 0.0034 | 0.0015 | 0.0058 | 0.0030 | 0.0089 | 0.0074 | 0.0294 | 0.0164 | 0.0684 | 0.0406 | 0.1042 | 0.0619 | 0.1097 | 0.0584 | 0.1415 | 0.0780 | 0.5287 | 0.7328 | 0.0006 | 0.0003 | 0.0010 | 0.0001 | 0.0022 | 0.0029 | 0.0064 | 0.0067 | 0.0146 | 0.0168 | 0.0254 | 0.0283 | 0.0235 | 0.0230 | 0.0296 | 0.0320 | 0.8967 | 0.8898 | 0.0005 | 0.0025 | 0.0033 | 0.0051 | 0.0060 | 0.0132 | 0.0098 | 0.0229 | 0.0280 | 0.0467 | 0.0282 | 0.0642 | 0.0358 | 0.0778 | 0.0499 | 0.0999 | 0.8385 | 0.6677 | 0.0009 | 0.0007 | 0.0024 | 0.0073 | 0.0189 | 0.0239 | 0.0284 | 0.0375 | 0.8799 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.1305 | 0.44 | 1.002 | 0.4054 | 46.1 | 458.785 | 7687.85 | 234458 | 0.5483 | 0.1268 | 0.0123 | 0.0015 | 0.0555 | 0.0107 | 0.1399 | 0.0297 | 0.2151 | 0.0734 | 0.2476 | 0.1533 | 0.1919 | 0.2308 | 0.1031 | 0.2579 | 0.0306 | 0.1797 | 0.0042 | 0.0631 | 0.0008 | 0.0001 | 0.0083 | 0.0014 | 0.0270 | 0.0074 | 0.0633 | 0.0263 | 0.1189 | 0.0658 | 0.1643 | 0.1156 | 0.2017 | 0.2003 | 0.2201 | 0.2840 | 0.1956 | 0.2992 | 0.1197 | 0.2233 | 0.1816 | 0.2100 | 0.1733 | 0.1903 | 0.1579 | 0.1256 | 0.1231 | 0.0803 | 0.0916 | 0.0538 | 0.0625 | 0.0439 | 0.0525 | 0.0381 | 0.0379 | 0.0347 | 0.0066 | 0.0454 | 0.0962 | 0.1383 | 0.1787 | 0.1873 | 0.1512 | 0.1164 | 0.0797 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 956 | 595 | | 1268 | 9881 | 91.4 | 16.59 | 53.65 | 107.18 | 71 | 75 | 80 | 84 | 89 | 95 | 101 | 108 | 115 | 0.0764 | 755 | 0.686 | 37.00 | 9.00 | 2 | 0.0694 | 88 | 0.0675 | 0.54 | 2.946 | 0.7664 | 8636.4 | 841834 | 84500000 | 8730000000 | 0.3820 | 0.2594 | 0.0034 | 0.0000 | 0.0101 | 0.0000 | 0.0190 | 0.0000 | 0.0324 | 0.0056 | 0.0738 | 0.0272 | 0.1309 | 0.0769 | 0.1119 | 0.0408 | 0.1644 | 0.0665 | 0.4541 | 0.7830 | 0.0027 | 0.0000 | 0.0063 | 0.0000 | 0.0081 | 0.0000 | 0.0181 | 0.0055 | 0.0433 | 0.0268 | 0.0668 | 0.0702 | 0.0542 | 0.0292 | 0.0713 | 0.0489 | 0.7292 | 0.8194 | 0.0140 | 0.0526 | 0.0047 | 0.0000 | 0.0607 | 0.0526 | 0.0467 | 0.1579 | 0.1215 | 0.4211 | 0.1449 | 0.1053 | 0.1402 | 0.0000 | 0.1869 | 0.1579 | 0.2804 | 0.0526 | 0.0017 | 0.0066 | 0.0150 | 0.0282 | 0.0465 | 0.0781 | 0.0880 | 0.0698 | 0.6661 | 5 | 7 | 8 | 10 | 13 | 24 | 48 | 81 | 142 | 0.0679 | 5.33 | 3.029 | 0.5252 | 14364.0 | 10100000 | 10700000000 | 13000000000000 | 0.4553 | 0.2110 | 0.0320 | 0.0021 | 0.1446 | 0.0121 | 0.2309 | 0.0605 | 0.2156 | 0.1517 | 0.1307 | 0.1944 | 0.1154 | 0.1830 | 0.0654 | 0.1161 | 0.0501 | 0.1061 | 0.0153 | 0.1738 | 0.0000 | 0.0000 | 0.0019 | 0.0003 | 0.0042 | 0.0040 | 0.0160 | 0.0130 | 0.0521 | 0.0454 | 0.0878 | 0.0802 | 0.0597 | 0.0519 | 0.0917 | 0.0918 | 0.6867 | 0.7134 | 0.0012 | 0.0009 | 0.0012 | 0.0019 | 0.0058 | 0.0047 | 0.0162 | 0.0160 | 0.0697 | 0.0782 | 0.1107 | 0.1097 | 0.0680 | 0.0763 | 0.1190 | 0.1266 | 0.6082 | 0.5857 | 0.0000 | 0.0029 | 0.0040 | 0.0169 | 0.0606 | 0.0948 | 0.0671 | 0.1168 | 0.6369 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1169 | 718 | | 3803 | 6960 | 84.4 | 20.56 | 84.20 | 75.35 | 60 | 68 | 73 | 77 | 82 | 88 | 94 | 101 | 111 | 0.1295 | 901 | 1.055 | 100.65 | 36.80 | 3 | 0.0702 | 267 | 0.0048 | 9.98 | 5.662 | 0.3488 | 7539.7 | 712809 | 71300000 | 7550000000 | 0.4461 | 0.2010 | 0.0035 | 0.0000 | 0.0035 | 0.0006 | 0.0133 | 0.0014 | 0.0434 | 0.0049 | 0.1018 | 0.0301 | 0.1540 | 0.0703 | 0.1717 | 0.0627 | 0.1965 | 0.1162 | 0.3124 | 0.7138 | 0.0007 | 0.0000 | 0.0013 | 0.0003 | 0.0026 | 0.0008 | 0.0141 | 0.0025 | 0.0434 | 0.0234 | 0.0736 | 0.0485 | 0.0696 | 0.0294 | 0.0923 | 0.0539 | 0.7024 | 0.8412 | 0.0038 | 0.0423 | 0.0153 | 0.0329 | 0.0204 | 0.0798 | 0.1008 | 0.1596 | 0.1288 | 0.1831 | 0.1760 | 0.2019 | 0.1492 | 0.1221 | 0.1620 | 0.0845 | 0.2436 | 0.0939 | 0.0016 | 0.0066 | 0.0131 | 0.0334 | 0.0826 | 0.1067 | 0.1100 | 0.1379 | 0.5082 | 21 | 29 | 36 | 45 | 57 | 72 | 93 | 129 | 196 | 0.0215 | 6.08 | 4.792 | 0.5469 | 12767.1 | 2810000 | 768000000 | 242000000000 | 0.5949 | 0.1190 | 0.0236 | 0.0027 | 0.0754 | 0.0155 | 0.1471 | 0.0354 | 0.1680 | 0.0787 | 0.1916 | 0.1437 | 0.1471 | 0.1641 | 0.1235 | 0.1433 | 0.0836 | 0.1636 | 0.0400 | 0.2530 | 0.0027 | 0.0010 | 0.0061 | 0.0052 | 0.0097 | 0.0081 | 0.0289 | 0.0240 | 0.0729 | 0.0672 | 0.1069 | 0.0930 | 0.0901 | 0.0750 | 0.1103 | 0.1066 | 0.5724 | 0.6198 | 0.0048 | 0.0038 | 0.0112 | 0.0038 | 0.0117 | 0.0102 | 0.0363 | 0.0326 | 0.0811 | 0.0856 | 0.1323 | 0.1475 | 0.0961 | 0.0958 | 0.1126 | 0.1315 | 0.5139 | 0.4891 | 0.0013 | 0.0093 | 0.0160 | 0.0388 | 0.0835 | 0.1210 | 0.0923 | 0.1151 | 0.5228 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 56 | 911 | | 384 | 7332 | 60.6 | 12.76 | 165.06 | 118.18 | 45 | 50 | 53 | 57 | 60 | 63 | 67 | 71 | 76 | 0.0614 | 450 | 0.519 | 130.54 | 26.91 | 0 | 1.0260 | 394 | 0.0099 | 9.19 | 4.826 | 0.3167 | 3828.9 | 252540 | 17400000 | 1250000000 | 0.4554 | 0.1729 | 0.0036 | 0.0000 | 0.0109 | 0.0028 | 0.0182 | 0.0055 | 0.0691 | 0.0194 | 0.1309 | 0.0720 | 0.1709 | 0.1219 | 0.1782 | 0.0914 | 0.2000 | 0.1607 | 0.2182 | 0.5263 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0093 | 0.0027 | 0.0247 | 0.0107 | 0.0957 | 0.0587 | 0.1235 | 0.1147 | 0.1173 | 0.0667 | 0.1420 | 0.1333 | 0.4877 | 0.6107 | 0.1020 | 0.0000 | 0.0612 | 0.1429 | 0.1224 | 0.0714 | 0.1020 | 0.3571 | 0.1633 | 0.2857 | 0.1837 | 0.0714 | 0.1633 | 0.0714 | 0.0612 | 0.0000 | 0.0408 | 0.0000 | 0.0053 | 0.0000 | 0.0106 | 0.0638 | 0.1596 | 0.1702 | 0.1596 | 0.1915 | 0.2394 | 18 | 37 | 71 | 117 | 158 | 195 | 232 | 274 | 329 | 0.0075 | 22.50 | 6.081 | 0.3343 | 41207.1 | 12200000 | 3970000000 | 1400000000000 | 0.4642 | 0.1955 | 0.0148 | 0.0016 | 0.1134 | 0.0089 | 0.1997 | 0.0335 | 0.1935 | 0.0895 | 0.1671 | 0.1734 | 0.1507 | 0.1952 | 0.0870 | 0.1593 | 0.0583 | 0.1613 | 0.0155 | 0.1774 | 0.0000 | 0.0000 | 0.0005 | 0.0013 | 0.0024 | 0.0011 | 0.0128 | 0.0077 | 0.0443 | 0.0302 | 0.0775 | 0.0562 | 0.0828 | 0.0523 | 0.1239 | 0.0826 | 0.6558 | 0.7687 | 0.0003 | 0.0023 | 0.0052 | 0.0099 | 0.0108 | 0.0185 | 0.0241 | 0.0468 | 0.0927 | 0.1342 | 0.1524 | 0.1640 | 0.1405 | 0.1486 | 0.1552 | 0.1721 | 0.4188 | 0.3036 | 0.0011 | 0.0025 | 0.0040 | 0.0178 | 0.0627 | 0.1136 | 0.1110 | 0.1627 | 0.5246 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1200 | 960 | | 312 | 3292 | 82.5 | 11.29 | 23.21 | 72.43 | 68 | 73 | 76 | 79 | 82 | 86 | 89 | 93 | 97 | 0.1206 | 397 | 1.136 | 33.29 | 11.66 | 2 | 0.2724 | 85 | 0.0754 | 0.90 | 2.811 | 0.6827 | 6932.2 | 592793 | 51500000 | 4550000000 | 0.3990 | 0.2389 | 0.0037 | 0.0000 | 0.0000 | 0.0032 | 0.0112 | 0.0000 | 0.0485 | 0.0096 | 0.0672 | 0.0737 | 0.1194 | 0.0833 | 0.0933 | 0.0481 | 0.1604 | 0.0705 | 0.4963 | 0.7115 | 0.0034 | 0.0000 | 0.0000 | 0.0032 | 0.0069 | 0.0000 | 0.0206 | 0.0096 | 0.0481 | 0.0737 | 0.0997 | 0.0833 | 0.0378 | 0.0481 | 0.0722 | 0.0705 | 0.7113 | 0.7115 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.2609 | 0.0000 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0120 | 0.0180 | 0.0299 | 0.0539 | 0.0898 | 0.2275 | 0.0958 | 0.1078 | 0.3653 | 5 | 6 | 8 | 8 | 9 | 10 | 11 | 12 | 16 | 0.2788 | 2.99 | 1.539 | 0.6666 | 5783.0 | 2740000 | 1470000000 | 851000000000 | 0.3576 | 0.2571 | 0.1333 | 0.2774 | 0.2167 | 0.1473 | 0.3500 | 0.1130 | 0.1833 | 0.1541 | 0.0833 | 0.1336 | 0.0333 | 0.1199 | 0.0000 | 0.0411 | 0.0000 | 0.0103 | 0.0000 | 0.0034 | 0.0217 | 0.1656 | 0.0072 | 0.0879 | 0.0109 | 0.0573 | 0.0217 | 0.0613 | 0.0435 | 0.0327 | 0.0942 | 0.0675 | 0.0471 | 0.0409 | 0.0870 | 0.0695 | 0.6667 | 0.4172 | 0.0000 | 0.0000 | 0.0093 | 0.0000 | 0.0046 | 0.0000 | 0.0139 | 0.0203 | 0.0509 | 0.0711 | 0.1111 | 0.0863 | 0.0556 | 0.0761 | 0.0787 | 0.0863 | 0.6759 | 0.6599 | 0.0042 | 0.0042 | 0.0211 | 0.0253 | 0.0506 | 0.0717 | 0.0717 | 0.0928 | 0.6582 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 274 | 724 | | 833 | 13982 | 37.7 | 9.22 | 181.15 | 216.84 | 28 | 30 | 32 | 34 | 36 | 38 | 40 | 44 | 50 | 0.0473 | 662 | 1.199 | 23.54 | 8.94 | 3 | 0.0732 | 61 | 0.0229 | 2.86 | 4.160 | 0.4919 | 1505.4 | 64089 | 2920000 | 142000000 | 0.4024 | 0.2135 | 0.0039 | 0.0000 | 0.0197 | 0.0000 | 0.0197 | 0.0000 | 0.0907 | 0.0156 | 0.1243 | 0.0650 | 0.1460 | 0.0728 | 0.1913 | 0.1027 | 0.2012 | 0.1352 | 0.2032 | 0.6086 | 0.0031 | 0.0000 | 0.0108 | 0.0000 | 0.0154 | 0.0000 | 0.0555 | 0.0132 | 0.0709 | 0.0505 | 0.0755 | 0.0457 | 0.1248 | 0.0721 | 0.1171 | 0.0805 | 0.5270 | 0.7380 | 0.0141 | 0.0317 | 0.0070 | 0.0317 | 0.0211 | 0.0317 | 0.0845 | 0.0794 | 0.1268 | 0.1746 | 0.1479 | 0.1587 | 0.0775 | 0.1429 | 0.1831 | 0.1111 | 0.3380 | 0.2381 | 0.0089 | 0.0417 | 0.0357 | 0.0774 | 0.0923 | 0.1220 | 0.1042 | 0.1399 | 0.3780 | 13 | 15 | 18 | 25 | 72 | 155 | 247 | 356 | 505 | 0.1047 | 25.13 | 4.988 | 0.5234 | 79833.1 | 46100000 | 31400000000 | 24300000000000 | 0.5786 | 0.1133 | 0.0295 | 0.0009 | 0.1412 | 0.0151 | 0.2513 | 0.0722 | 0.1854 | 0.1324 | 0.1750 | 0.2019 | 0.1161 | 0.2027 | 0.0537 | 0.1479 | 0.0286 | 0.1209 | 0.0191 | 0.1062 | 0.0005 | 0.0000 | 0.0021 | 0.0008 | 0.0031 | 0.0022 | 0.0102 | 0.0085 | 0.0401 | 0.0383 | 0.0610 | 0.0504 | 0.0571 | 0.0510 | 0.0875 | 0.0745 | 0.7384 | 0.7744 | 0.0004 | 0.0002 | 0.0013 | 0.0015 | 0.0054 | 0.0051 | 0.0173 | 0.0245 | 0.0542 | 0.0646 | 0.0886 | 0.0970 | 0.0864 | 0.1030 | 0.1156 | 0.1191 | 0.6309 | 0.5849 | 0.0004 | 0.0035 | 0.0025 | 0.0146 | 0.0434 | 0.0766 | 0.0726 | 0.0991 | 0.6873 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 946 | 911 | | 326 | 5218 | 83.2 | 12.55 | 6.61 | 2.23 | 66 | 72 | 76 | 80 | 84 | 87 | 90 | 94 | 100 | 0.0922 | 481 | 0.870 | 40.79 | 10.82 | 5 | 0.2883 | 94 | 0.0484 | 1.29 | 3.265 | 0.6193 | 7072.0 | 613833 | 54300000 | 4880000000 | 0.3970 | 0.2342 | 0.0039 | 0.0000 | 0.0039 | 0.0000 | 0.0078 | 0.0000 | 0.0310 | 0.0153 | 0.0698 | 0.0429 | 0.1512 | 0.0798 | 0.1163 | 0.0583 | 0.1860 | 0.0828 | 0.4302 | 0.7209 | 0.0034 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0206 | 0.0153 | 0.0309 | 0.0429 | 0.0997 | 0.0798 | 0.0550 | 0.0583 | 0.0928 | 0.0828 | 0.6907 | 0.7209 | 0.0303 | 0.0000 | 0.0909 | 0.0000 | 0.0909 | 0.0000 | 0.1818 | 0.0000 | 0.1818 | 0.0000 | 0.2121 | 0.0000 | 0.1212 | 0.0000 | 0.0606 | 0.0000 | 0.0303 | 0.0000 | 0.0055 | 0.0000 | 0.0110 | 0.0440 | 0.0714 | 0.1484 | 0.1154 | 0.2033 | 0.4011 | 4 | 5 | 6 | 6 | 6 | 7 | 7 | 9 | 9 | 0.0270 | 9.36 | 4.124 | 0.3431 | 48.6 | 391.422 | 3419.3 | 32319.8 | 0.5324 | 0.1461 | 0.0043 | 0.0011 | 0.0274 | 0.0040 | 0.0990 | 0.0214 | 0.1877 | 0.0631 | 0.2444 | 0.1213 | 0.2369 | 0.2069 | 0.1372 | 0.2618 | 0.0545 | 0.2256 | 0.0086 | 0.0948 | 0.0005 | 0.0002 | 0.0028 | 0.0019 | 0.0165 | 0.0091 | 0.0505 | 0.0369 | 0.1170 | 0.0831 | 0.1931 | 0.1470 | 0.2540 | 0.2323 | 0.2307 | 0.2820 | 0.1350 | 0.2075 | 0.1429 | 0.4528 | 0.2778 | 0.2397 | 0.2169 | 0.0896 | 0.1614 | 0.0557 | 0.0750 | 0.0436 | 0.0547 | 0.0533 | 0.0335 | 0.0412 | 0.0247 | 0.0194 | 0.0132 | 0.0048 | 0.0201 | 0.0768 | 0.1695 | 0.2209 | 0.1962 | 0.1531 | 0.0866 | 0.0497 | 0.0271 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1173 | 230 | | 893 | 1587 | 58.0 | 13.43 | 491.67 | 350.26 | 39 | 45 | 50 | 54 | 59 | 63 | 67 | 71 | 75 | 0.1878 | 298 | 1.216 | 22.85 | 8.25 | 1 | 0.0694 | 62 | 0.0063 | 5.77 | 5.275 | 0.3973 | 3548.7 | 226676 | 15000000 | 1020000000 | 0.4245 | 0.2042 | 0.0041 | 0.0000 | 0.0104 | 0.0000 | 0.0228 | 0.0012 | 0.0352 | 0.0119 | 0.1056 | 0.0380 | 0.1201 | 0.0403 | 0.1677 | 0.0712 | 0.1822 | 0.0830 | 0.3520 | 0.7544 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0058 | 0.0012 | 0.0159 | 0.0116 | 0.0418 | 0.0359 | 0.0390 | 0.0348 | 0.0592 | 0.0475 | 0.0649 | 0.0487 | 0.7706 | 0.8204 | 0.0095 | 0.0500 | 0.0143 | 0.1000 | 0.0190 | 0.0500 | 0.0476 | 0.2000 | 0.1381 | 0.3000 | 0.1095 | 0.1000 | 0.1810 | 0.0000 | 0.1905 | 0.2000 | 0.2905 | 0.0000 | 0.0043 | 0.0151 | 0.0151 | 0.0129 | 0.0430 | 0.0688 | 0.0860 | 0.1011 | 0.6538 | 107 | 162 | 233 | 315 | 418 | 517 | 636 | 803 | 998 | 0.0021 | 39.34 | 6.548 | 0.2363 | 364349.0 | 335000000 | 350000000000 | 398000000000000 | 0.5161 | 0.1411 | 0.0070 | 0.0000 | 0.0702 | 0.0035 | 0.1579 | 0.0228 | 0.2316 | 0.0683 | 0.2140 | 0.1278 | 0.1789 | 0.2277 | 0.0877 | 0.1611 | 0.0386 | 0.1664 | 0.0140 | 0.2224 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0061 | 0.0020 | 0.0255 | 0.0201 | 0.0522 | 0.0413 | 0.0765 | 0.0554 | 0.0667 | 0.0564 | 0.1129 | 0.0816 | 0.6590 | 0.7432 | 0.0019 | 0.0000 | 0.0000 | 0.0047 | 0.0111 | 0.0213 | 0.0390 | 0.0332 | 0.0686 | 0.0900 | 0.1317 | 0.1232 | 0.0891 | 0.0853 | 0.1132 | 0.1422 | 0.5455 | 0.5000 | 0.0000 | 0.0059 | 0.0089 | 0.0341 | 0.0548 | 0.0904 | 0.0919 | 0.1407 | 0.5733 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1179 | 272 | | 484 | 417 | 15.1 | 6.24 | 5.44 | 2.42 | 10 | 11 | 12 | 12 | 13 | 15 | 16 | 18 | 23 | 0.4964 | 207 | 0.834 | 37.74 | 12.04 | 0 | 0.2397 | 116 | 0.0096 | 14.01 | 4.972 | 0.3037 | 265.5 | 5621.95 | 142364 | 4170000 | 0.3690 | 0.2458 | 0.0041 | 0.0000 | 0.0207 | 0.0000 | 0.0664 | 0.0000 | 0.1660 | 0.0426 | 0.1618 | 0.0727 | 0.1826 | 0.1053 | 0.1826 | 0.1328 | 0.1369 | 0.1529 | 0.0788 | 0.4937 | 0.0000 | 0.0000 | 0.0146 | 0.0000 | 0.0292 | 0.0000 | 0.0437 | 0.0325 | 0.0787 | 0.0433 | 0.1108 | 0.0584 | 0.1224 | 0.0714 | 0.1866 | 0.0952 | 0.4140 | 0.6991 | 0.0392 | 0.0000 | 0.0392 | 0.0476 | 0.0686 | 0.0635 | 0.0490 | 0.0794 | 0.0784 | 0.1429 | 0.1961 | 0.1111 | 0.0980 | 0.1111 | 0.1275 | 0.1111 | 0.3039 | 0.3333 | 0.0051 | 0.0256 | 0.0718 | 0.0821 | 0.1026 | 0.1333 | 0.1385 | 0.1179 | 0.3231 | 3 | 3 | 4 | 5 | 5 | 7 | 7 | 7 | 9 | 0.0300 | 14.00 | 3.917 | 0.2952 | 35.4 | 257.772 | 2032.6 | 17052.4 | 0.3900 | 0.1941 | 0.1136 | 0.0290 | 0.2652 | 0.0773 | 0.2803 | 0.2174 | 0.1667 | 0.2560 | 0.0909 | 0.2029 | 0.0530 | 0.1353 | 0.0303 | 0.0628 | 0.0000 | 0.0145 | 0.0000 | 0.0048 | 0.0032 | 0.0000 | 0.0194 | 0.0079 | 0.0809 | 0.0159 | 0.1748 | 0.0714 | 0.2201 | 0.1720 | 0.2071 | 0.1746 | 0.1909 | 0.2302 | 0.0906 | 0.2169 | 0.0129 | 0.1111 | 0.0734 | 0.0760 | 0.1751 | 0.2047 | 0.3277 | 0.3392 | 0.2260 | 0.2222 | 0.1186 | 0.0877 | 0.0395 | 0.0292 | 0.0395 | 0.0409 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0433 | 0.1300 | 0.2202 | 0.2238 | 0.1805 | 0.1336 | 0.0542 | 0.0072 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 695 | 131 | | 413 | 5107 | 82.1 | 20.31 | 279.73 | 253.72 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 98 | 113 | 0.0832 | 425 | 0.434 | 131.03 | 25.55 | 1 | 1.0266 | 424 | 0.0060 | 18.02 | 5.295 | 0.2565 | 7150.1 | 660661 | 64600000 | 6650000000 | 0.4371 | 0.1916 | 0.0042 | 0.0027 | 0.0042 | 0.0000 | 0.0333 | 0.0027 | 0.0667 | 0.0239 | 0.2042 | 0.0557 | 0.1708 | 0.1326 | 0.1708 | 0.0849 | 0.1667 | 0.1618 | 0.1792 | 0.5358 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0219 | 0.0121 | 0.0909 | 0.0388 | 0.1285 | 0.1068 | 0.1003 | 0.0485 | 0.1317 | 0.0801 | 0.5235 | 0.7136 | 0.0127 | 0.0000 | 0.0506 | 0.0571 | 0.0253 | 0.0286 | 0.1266 | 0.3143 | 0.2025 | 0.1429 | 0.1772 | 0.2571 | 0.1392 | 0.2000 | 0.1266 | 0.0000 | 0.1392 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0914 | 0.1452 | 0.1935 | 0.1774 | 0.1452 | 0.2366 | 25 | 49 | 96 | 153 | 212 | 275 | 354 | 477 | 655 | 0.0063 | 78.62 | 6.665 | 0.3190 | 142608.0 | 95700000 | 75600000000 | 66600000000000 | 0.5065 | 0.1700 | 0.0221 | 0.0019 | 0.0858 | 0.0044 | 0.1495 | 0.0386 | 0.1507 | 0.0880 | 0.1667 | 0.1381 | 0.1507 | 0.1837 | 0.1164 | 0.1343 | 0.0931 | 0.1279 | 0.0650 | 0.2831 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0045 | 0.0010 | 0.0179 | 0.0102 | 0.0595 | 0.0459 | 0.0965 | 0.0856 | 0.0892 | 0.0652 | 0.1071 | 0.0883 | 0.6244 | 0.7037 | 0.0018 | 0.0007 | 0.0031 | 0.0044 | 0.0067 | 0.0095 | 0.0329 | 0.0352 | 0.0940 | 0.1232 | 0.1416 | 0.1576 | 0.1159 | 0.1188 | 0.1495 | 0.1503 | 0.4545 | 0.4003 | 0.0010 | 0.0015 | 0.0050 | 0.0223 | 0.0819 | 0.1166 | 0.1052 | 0.1454 | 0.5211 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1272 | 883 | | 1150 | 8995 | 239.8 | 65.75 | 123.62 | 67.46 | 158 | 173 | 191 | 209 | 232 | 258 | 286 | 306 | 330 | 0.0845 | 760 | 0.982 | 95.52 | 25.18 | 3 | 0.2000 | 230 | 0.0013 | 67.56 | 6.741 | 0.1434 | 61808.3 | 17000000 | 4910000000 | 1480000000000 | 0.4669 | 0.1629 | 0.0043 | 0.0010 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0469 | 0.0068 | 0.1919 | 0.0476 | 0.2751 | 0.1322 | 0.1663 | 0.0787 | 0.1215 | 0.1351 | 0.1919 | 0.5986 | 0.0013 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0150 | 0.0045 | 0.0614 | 0.0303 | 0.0852 | 0.1025 | 0.0576 | 0.0357 | 0.0827 | 0.0677 | 0.6967 | 0.7585 | 0.0000 | 0.0108 | 0.0000 | 0.0323 | 0.0000 | 0.0538 | 0.0274 | 0.1720 | 0.1337 | 0.1398 | 0.1125 | 0.1613 | 0.1155 | 0.1720 | 0.1763 | 0.1075 | 0.4347 | 0.1505 | 0.0000 | 0.0000 | 0.0019 | 0.0242 | 0.0576 | 0.1022 | 0.0762 | 0.0929 | 0.6450 | 49 | 64 | 78 | 92 | 110 | 130 | 153 | 178 | 216 | 0.0036 | 19.57 | 6.129 | 0.3167 | 19833.3 | 3880000 | 886000000 | 230000000000 | 0.5219 | 0.1301 | 0.0186 | 0.0026 | 0.0971 | 0.0077 | 0.1631 | 0.0208 | 0.1817 | 0.0612 | 0.1719 | 0.1229 | 0.1524 | 0.1718 | 0.1115 | 0.1593 | 0.0678 | 0.1860 | 0.0358 | 0.2677 | 0.0012 | 0.0012 | 0.0034 | 0.0023 | 0.0078 | 0.0055 | 0.0254 | 0.0158 | 0.0730 | 0.0453 | 0.1045 | 0.0772 | 0.1015 | 0.0721 | 0.1389 | 0.1101 | 0.5443 | 0.6705 | 0.0011 | 0.0082 | 0.0102 | 0.0169 | 0.0186 | 0.0416 | 0.0629 | 0.0914 | 0.1265 | 0.1422 | 0.1757 | 0.1792 | 0.1409 | 0.1555 | 0.1452 | 0.1247 | 0.3188 | 0.2402 | 0.0018 | 0.0043 | 0.0128 | 0.0337 | 0.0856 | 0.1573 | 0.1206 | 0.1418 | 0.4421 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 958 | 125 | | 2932 | 10604 | 196.6 | 65.96 | 9.01 | 4.41 | 127 | 138 | 150 | 164 | 179 | 198 | 223 | 249 | 301 | 0.0658 | 698 | 0.614 | 76.01 | 21.95 | 1 | 0.0836 | 245 | 0.0079 | 2.74 | 5.180 | 0.5006 | 42980.6 | 10400000 | 2760000000 | 788000000000 | 0.4076 | 0.2304 | 0.0043 | 0.0013 | 0.0035 | 0.0013 | 0.0112 | 0.0042 | 0.0371 | 0.0097 | 0.0569 | 0.0295 | 0.1320 | 0.0687 | 0.1217 | 0.0442 | 0.1639 | 0.0720 | 0.4694 | 0.7692 | 0.0021 | 0.0011 | 0.0021 | 0.0007 | 0.0053 | 0.0032 | 0.0137 | 0.0064 | 0.0217 | 0.0207 | 0.0455 | 0.0454 | 0.0418 | 0.0264 | 0.0561 | 0.0482 | 0.8117 | 0.8477 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0109 | 0.0047 | 0.0301 | 0.0165 | 0.0342 | 0.0425 | 0.0861 | 0.0778 | 0.0697 | 0.0472 | 0.0765 | 0.0802 | 0.6899 | 0.7311 | 0.0017 | 0.0025 | 0.0042 | 0.0151 | 0.0260 | 0.0519 | 0.0511 | 0.0611 | 0.7864 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 14 | 0.0111 | 13.72 | 5.076 | 0.3038 | 100.7 | 1416.1 | 25055.2 | 539238 | 0.4587 | 0.1802 | 0.0400 | 0.0040 | 0.1247 | 0.0070 | 0.2092 | 0.0206 | 0.2582 | 0.0465 | 0.1991 | 0.1010 | 0.1141 | 0.1792 | 0.0447 | 0.2550 | 0.0098 | 0.2595 | 0.0003 | 0.1273 | 0.0087 | 0.0002 | 0.0392 | 0.0012 | 0.0841 | 0.0078 | 0.1282 | 0.0233 | 0.1444 | 0.0654 | 0.1470 | 0.1201 | 0.1169 | 0.1781 | 0.1209 | 0.2377 | 0.2107 | 0.3662 | 0.1147 | 0.1071 | 0.0900 | 0.0750 | 0.0862 | 0.0679 | 0.0718 | 0.0968 | 0.0938 | 0.0859 | 0.1045 | 0.1000 | 0.0836 | 0.1019 | 0.0957 | 0.1167 | 0.2595 | 0.2487 | 0.0483 | 0.0956 | 0.1102 | 0.1089 | 0.1085 | 0.0986 | 0.0902 | 0.1128 | 0.2269 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1262 | 191 | | 1146 | 5093 | 90.2 | 37.96 | 173.01 | 291.74 | 37 | 56 | 70 | 80 | 89 | 98 | 108 | 122 | 139 | 0.1056 | 538 | 0.246 | 326.81 | 58.25 | 3 | 1.2321 | 1412 | 0.0022 | 29.57 | 6.284 | 0.2125 | 9584.0 | 1150000 | 154000000 | 22500000000 | 0.3879 | 0.2271 | 0.0045 | 0.0000 | 0.0182 | 0.0000 | 0.0795 | 0.0040 | 0.0932 | 0.0173 | 0.1295 | 0.0840 | 0.1705 | 0.1280 | 0.1705 | 0.1333 | 0.1955 | 0.1453 | 0.1386 | 0.4880 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0064 | 0.0032 | 0.0446 | 0.0319 | 0.0841 | 0.0554 | 0.0828 | 0.0405 | 0.1338 | 0.0692 | 0.6459 | 0.7998 | 0.0000 | 0.0106 | 0.0087 | 0.0212 | 0.0203 | 0.0159 | 0.0580 | 0.0847 | 0.1130 | 0.2328 | 0.1652 | 0.2011 | 0.1275 | 0.1164 | 0.1739 | 0.1270 | 0.3333 | 0.1905 | 0.0035 | 0.0018 | 0.0089 | 0.0319 | 0.0904 | 0.1294 | 0.1188 | 0.1489 | 0.4663 | 14 | 16 | 18 | 21 | 25 | 39 | 104 | 323 | 583 | 0.0764 | 34.57 | 4.571 | 0.5346 | 115023.0 | 109000000 | 127000000000 | 170000000000000 | 0.7263 | 0.0444 | 0.0738 | 0.0122 | 0.3020 | 0.0550 | 0.3087 | 0.1498 | 0.1477 | 0.2385 | 0.1208 | 0.2599 | 0.0201 | 0.1346 | 0.0134 | 0.0642 | 0.0134 | 0.0367 | 0.0000 | 0.0489 | 0.0000 | 0.0007 | 0.0028 | 0.0013 | 0.0028 | 0.0033 | 0.0264 | 0.0209 | 0.0674 | 0.0712 | 0.1035 | 0.0935 | 0.0757 | 0.0745 | 0.1070 | 0.1085 | 0.6143 | 0.6261 | 0.0016 | 0.0000 | 0.0023 | 0.0025 | 0.0047 | 0.0183 | 0.0287 | 0.0241 | 0.0636 | 0.0665 | 0.1116 | 0.1155 | 0.0853 | 0.0840 | 0.1124 | 0.1139 | 0.5899 | 0.5752 | 0.0007 | 0.0029 | 0.0066 | 0.0269 | 0.0655 | 0.1077 | 0.0852 | 0.1033 | 0.6012 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 395 | 909 | | 589 | 5786 | 12.0 | 2.37 | 6.24 | 2.23 | 9 | 10 | 11 | 11 | 12 | 12 | 13 | 14 | 15 | 0.0990 | 573 | 0.731 | 73.43 | 17.00 | 0 | 0.3192 | 188 | 0.0185 | 6.32 | 4.289 | 0.3960 | 150.6 | 1953.66 | 26252.6 | 364792 | 0.3695 | 0.2656 | 0.0046 | 0.0000 | 0.0069 | 0.0018 | 0.0324 | 0.0036 | 0.0694 | 0.0164 | 0.1019 | 0.0455 | 0.1343 | 0.0764 | 0.1898 | 0.1218 | 0.1736 | 0.1818 | 0.2870 | 0.5527 | 0.0000 | 0.0000 | 0.0077 | 0.0000 | 0.0174 | 0.0017 | 0.0367 | 0.0156 | 0.0405 | 0.0363 | 0.0656 | 0.0554 | 0.1158 | 0.0606 | 0.1409 | 0.1125 | 0.5753 | 0.7180 | 0.0581 | 0.2857 | 0.0930 | 0.2500 | 0.1860 | 0.1071 | 0.1163 | 0.1786 | 0.1744 | 0.1071 | 0.1163 | 0.0714 | 0.0814 | 0.0000 | 0.1163 | 0.0000 | 0.0581 | 0.0000 | 0.0153 | 0.0337 | 0.0706 | 0.0982 | 0.1135 | 0.1350 | 0.1380 | 0.1503 | 0.2454 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0198 | 11.10 | 4.314 | 0.3248 | 43.9 | 336.777 | 2778.03 | 24382.5 | 0.5530 | 0.1191 | 0.0068 | 0.0000 | 0.0407 | 0.0041 | 0.1143 | 0.0182 | 0.2166 | 0.0597 | 0.2673 | 0.1261 | 0.2088 | 0.2311 | 0.1023 | 0.2725 | 0.0370 | 0.2133 | 0.0062 | 0.0750 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0121 | 0.0032 | 0.0364 | 0.0132 | 0.0907 | 0.0355 | 0.1684 | 0.0778 | 0.2678 | 0.1906 | 0.2778 | 0.3647 | 0.1454 | 0.3144 | 0.1144 | 0.2816 | 0.2397 | 0.3609 | 0.2950 | 0.2346 | 0.1896 | 0.0927 | 0.1073 | 0.0268 | 0.0392 | 0.0034 | 0.0141 | 0.0000 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0090 | 0.0356 | 0.0844 | 0.1569 | 0.2511 | 0.2490 | 0.1644 | 0.0477 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 815 | 163 | | 2938 | 15825 | 562.8 | 165.66 | 10.78 | 7.31 | 288 | 401 | 494 | 571 | 620 | 652 | 677 | 696 | 723 | 0.0577 | 913 | 0.956 | 43.93 | 14.04 | 1 | 0.0388 | 114 | 0.0035 | 13.77 | 6.195 | 0.3459 | 344227.0 | 221000000 | 147000000000 | 100000000000000 | 0.3768 | 0.2427 | 0.0046 | 0.0000 | 0.0069 | 0.0000 | 0.0069 | 0.0004 | 0.0299 | 0.0021 | 0.0851 | 0.0207 | 0.1219 | 0.0435 | 0.0913 | 0.0236 | 0.1296 | 0.0464 | 0.5238 | 0.8632 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0016 | 0.0213 | 0.0175 | 0.0344 | 0.0358 | 0.0222 | 0.0179 | 0.0376 | 0.0350 | 0.8822 | 0.8921 | 0.0022 | 0.0000 | 0.0078 | 0.0100 | 0.0111 | 0.0200 | 0.0388 | 0.0200 | 0.0543 | 0.0800 | 0.1008 | 0.1300 | 0.1008 | 0.0700 | 0.1274 | 0.1400 | 0.5570 | 0.5300 | 0.0006 | 0.0000 | 0.0000 | 0.0050 | 0.0233 | 0.0417 | 0.0267 | 0.0389 | 0.8639 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 19 | 0.2362 | 0.38 | 1.298 | 0.6613 | 169.5 | 3950.18 | 122472 | 4500000 | 0.5976 | 0.1040 | 0.0323 | 0.0020 | 0.0756 | 0.0106 | 0.1133 | 0.0336 | 0.1438 | 0.0726 | 0.1811 | 0.1062 | 0.1857 | 0.1514 | 0.1597 | 0.2027 | 0.0873 | 0.2334 | 0.0211 | 0.1876 | 0.0202 | 0.0012 | 0.0489 | 0.0067 | 0.0693 | 0.0257 | 0.0868 | 0.0568 | 0.1051 | 0.0848 | 0.1135 | 0.1256 | 0.1228 | 0.1539 | 0.1364 | 0.1840 | 0.2969 | 0.3614 | 0.0929 | 0.0470 | 0.0631 | 0.0212 | 0.0423 | 0.0131 | 0.0317 | 0.0217 | 0.0372 | 0.0359 | 0.0533 | 0.0606 | 0.0451 | 0.0526 | 0.0776 | 0.0773 | 0.5568 | 0.6705 | 0.0675 | 0.0951 | 0.0928 | 0.0982 | 0.0980 | 0.0940 | 0.0648 | 0.0545 | 0.3351 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1133 | 155 | | 893 | 1399 | 15.3 | 5.59 | 6.05 | 2.57 | 9 | 11 | 12 | 13 | 14 | 15 | 17 | 19 | 23 | 0.2437 | 341 | 0.631 | 86.21 | 19.03 | 0 | 0.2520 | 225 | 0.0063 | 15.00 | 5.353 | 0.2862 | 266.3 | 5252.12 | 117067 | 2910000 | 0.3793 | 0.2519 | 0.0048 | 0.0028 | 0.0333 | 0.0000 | 0.0643 | 0.0127 | 0.1452 | 0.0325 | 0.1786 | 0.0734 | 0.2262 | 0.0805 | 0.1762 | 0.1427 | 0.1143 | 0.2260 | 0.0571 | 0.4294 | 0.0000 | 0.0000 | 0.0120 | 0.0000 | 0.0240 | 0.0059 | 0.0314 | 0.0202 | 0.0569 | 0.0308 | 0.0883 | 0.0403 | 0.1033 | 0.0664 | 0.1856 | 0.1151 | 0.4985 | 0.7212 | 0.0282 | 0.0444 | 0.0726 | 0.0667 | 0.0565 | 0.0963 | 0.0645 | 0.1037 | 0.1089 | 0.0889 | 0.1089 | 0.0963 | 0.1089 | 0.1185 | 0.1573 | 0.1481 | 0.2944 | 0.2370 | 0.0070 | 0.0282 | 0.0446 | 0.0845 | 0.1009 | 0.1056 | 0.1502 | 0.1291 | 0.3498 | 2 | 4 | 4 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0207 | 14.14 | 4.219 | 0.3005 | 43.2 | 342.525 | 2947.43 | 27112.9 | 0.5136 | 0.1528 | 0.0287 | 0.0010 | 0.1396 | 0.0117 | 0.2199 | 0.0321 | 0.2581 | 0.0884 | 0.1893 | 0.1574 | 0.1090 | 0.2235 | 0.0402 | 0.2673 | 0.0134 | 0.1720 | 0.0019 | 0.0466 | 0.0022 | 0.0000 | 0.0151 | 0.0048 | 0.0635 | 0.0032 | 0.1389 | 0.0415 | 0.2099 | 0.0909 | 0.2196 | 0.1085 | 0.2056 | 0.1699 | 0.1044 | 0.2759 | 0.0409 | 0.3054 | 0.1010 | 0.3289 | 0.2241 | 0.3156 | 0.1946 | 0.2089 | 0.1749 | 0.0800 | 0.1626 | 0.0444 | 0.0788 | 0.0222 | 0.0542 | 0.0000 | 0.0099 | 0.0000 | 0.0000 | 0.0000 | 0.0083 | 0.0320 | 0.0959 | 0.1337 | 0.2024 | 0.2237 | 0.1787 | 0.0959 | 0.0296 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1243 | 854 | | 722 | 7966 | 63.7 | 17.26 | 99.18 | 192.37 | 47 | 51 | 53 | 56 | 60 | 63 | 68 | 74 | 85 | 0.0734 | 585 | 0.421 | 183.11 | 37.80 | 0 | 0.8726 | 630 | 0.0093 | 10.56 | 5.018 | 0.3434 | 4360.7 | 324711 | 26600000 | 2420000000 | 0.4665 | 0.1732 | 0.0048 | 0.0000 | 0.0238 | 0.0000 | 0.0499 | 0.0060 | 0.0950 | 0.0255 | 0.1354 | 0.0510 | 0.1853 | 0.0990 | 0.1663 | 0.1049 | 0.1663 | 0.1094 | 0.1734 | 0.6042 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0128 | 0.0028 | 0.0475 | 0.0097 | 0.0786 | 0.0444 | 0.1408 | 0.0819 | 0.1261 | 0.0611 | 0.1481 | 0.0833 | 0.4388 | 0.7167 | 0.0000 | 0.0000 | 0.0317 | 0.0377 | 0.0159 | 0.0755 | 0.0952 | 0.0755 | 0.1825 | 0.3019 | 0.1825 | 0.1321 | 0.1508 | 0.0566 | 0.1508 | 0.2075 | 0.1905 | 0.1132 | 0.0036 | 0.0180 | 0.0288 | 0.0791 | 0.1259 | 0.1691 | 0.1295 | 0.1511 | 0.2950 | 10 | 12 | 14 | 15 | 17 | 19 | 31 | 113 | 371 | 0.1151 | 73.14 | 4.084 | 0.5429 | 46837.2 | 32700000 | 27500000000 | 26300000000000 | 0.6007 | 0.1115 | 0.2664 | 0.0211 | 0.4953 | 0.1607 | 0.2103 | 0.5011 | 0.0280 | 0.1882 | 0.0000 | 0.0782 | 0.0000 | 0.0338 | 0.0000 | 0.0127 | 0.0000 | 0.0042 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0022 | 0.0015 | 0.0056 | 0.0036 | 0.0185 | 0.0247 | 0.0888 | 0.0781 | 0.1355 | 0.1183 | 0.0748 | 0.0848 | 0.1231 | 0.1177 | 0.5509 | 0.5707 | 0.0006 | 0.0007 | 0.0013 | 0.0041 | 0.0083 | 0.0082 | 0.0230 | 0.0211 | 0.0856 | 0.0958 | 0.1540 | 0.1501 | 0.0818 | 0.0795 | 0.1176 | 0.1291 | 0.5278 | 0.5115 | 0.0012 | 0.0024 | 0.0054 | 0.0198 | 0.0929 | 0.1360 | 0.0827 | 0.1210 | 0.5386 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 402 | 136 | | 3297 | 12148 | 98.0 | 18.33 | 8.19 | 2.60 | 74 | 80 | 85 | 92 | 97 | 103 | 108 | 114 | 123 | 0.0740 | 899 | 0.685 | 83.76 | 26.42 | 1 | 0.0746 | 246 | 0.0399 | 0.86 | 3.490 | 0.6974 | 9940.2 | 1040000 | 113000000 | 12600000000 | 0.4461 | 0.1984 | 0.0050 | 0.0003 | 0.0077 | 0.0000 | 0.0149 | 0.0019 | 0.0398 | 0.0046 | 0.0430 | 0.0207 | 0.0742 | 0.0377 | 0.0972 | 0.0303 | 0.1470 | 0.0585 | 0.5712 | 0.8460 | 0.0026 | 0.0000 | 0.0018 | 0.0000 | 0.0048 | 0.0015 | 0.0183 | 0.0033 | 0.0202 | 0.0176 | 0.0352 | 0.0303 | 0.0421 | 0.0218 | 0.0546 | 0.0331 | 0.8204 | 0.8923 | 0.0251 | 0.0625 | 0.0309 | 0.0625 | 0.0502 | 0.1719 | 0.0598 | 0.1563 | 0.0927 | 0.1875 | 0.1544 | 0.1406 | 0.1216 | 0.0938 | 0.1564 | 0.0781 | 0.3089 | 0.0469 | 0.0024 | 0.0036 | 0.0134 | 0.0243 | 0.0389 | 0.0584 | 0.0833 | 0.1217 | 0.6539 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0144 | 12.37 | 4.643 | 0.3155 | 73.9 | 721.847 | 7566.38 | 84525.8 | 0.5238 | 0.1413 | 0.0153 | 0.0002 | 0.0771 | 0.0016 | 0.1639 | 0.0070 | 0.2274 | 0.0223 | 0.2309 | 0.0551 | 0.1655 | 0.1102 | 0.0864 | 0.1993 | 0.0283 | 0.3127 | 0.0052 | 0.2916 | 0.0011 | 0.0000 | 0.0072 | 0.0003 | 0.0296 | 0.0015 | 0.0604 | 0.0068 | 0.1020 | 0.0189 | 0.1625 | 0.0400 | 0.2241 | 0.0871 | 0.2509 | 0.2788 | 0.1621 | 0.5666 | 0.0905 | 0.3211 | 0.1651 | 0.2629 | 0.2052 | 0.1761 | 0.1949 | 0.1076 | 0.1565 | 0.0717 | 0.0987 | 0.0351 | 0.0583 | 0.0215 | 0.0222 | 0.0032 | 0.0085 | 0.0008 | 0.0051 | 0.0284 | 0.0735 | 0.1320 | 0.1649 | 0.1938 | 0.1874 | 0.1443 | 0.0706 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 902 | 486 | | 1571 | 8752 | 79.8 | 18.38 | 25.85 | 63.61 | 59 | 62 | 66 | 70 | 75 | 84 | 92 | 99 | 106 | 0.0978 | 856 | 0.759 | 104.01 | 24.21 | 3 | 0.1827 | 287 | 0.0137 | 2.82 | 4.627 | 0.5218 | 6709.4 | 592170 | 54600000 | 5230000000 | 0.4037 | 0.2309 | 0.0050 | 0.0000 | 0.0099 | 0.0000 | 0.0236 | 0.0000 | 0.0459 | 0.0067 | 0.0980 | 0.0299 | 0.1613 | 0.0552 | 0.1365 | 0.0579 | 0.1675 | 0.0685 | 0.3524 | 0.7818 | 0.0033 | 0.0000 | 0.0033 | 0.0000 | 0.0117 | 0.0000 | 0.0208 | 0.0045 | 0.0400 | 0.0248 | 0.0650 | 0.0446 | 0.0550 | 0.0299 | 0.0708 | 0.0350 | 0.7300 | 0.8611 | 0.0000 | 0.0299 | 0.0000 | 0.0746 | 0.0203 | 0.0597 | 0.0330 | 0.1642 | 0.0787 | 0.1045 | 0.1320 | 0.1493 | 0.1142 | 0.0746 | 0.1345 | 0.1194 | 0.4873 | 0.2239 | 0.0000 | 0.0057 | 0.0057 | 0.0213 | 0.0355 | 0.0682 | 0.0540 | 0.0753 | 0.7344 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 12 | 53 | 0.2949 | 7.14 | 2.200 | 0.6924 | 4714.0 | 1480000 | 590000000 | 281000000000 | 0.4076 | 0.1755 | 0.0603 | 0.0111 | 0.2915 | 0.0379 | 0.4824 | 0.1737 | 0.1407 | 0.2517 | 0.0101 | 0.2539 | 0.0101 | 0.1403 | 0.0050 | 0.0802 | 0.0000 | 0.0379 | 0.0000 | 0.0134 | 0.0008 | 0.0035 | 0.0041 | 0.0077 | 0.0154 | 0.0153 | 0.0170 | 0.0251 | 0.0519 | 0.0537 | 0.0787 | 0.0760 | 0.0463 | 0.0530 | 0.0779 | 0.0746 | 0.7078 | 0.6911 | 0.0019 | 0.0030 | 0.0039 | 0.0020 | 0.0048 | 0.0030 | 0.0087 | 0.0071 | 0.0571 | 0.0569 | 0.0871 | 0.0944 | 0.0600 | 0.0650 | 0.0794 | 0.0792 | 0.6970 | 0.6893 | 0.0018 | 0.0090 | 0.0045 | 0.0170 | 0.0502 | 0.0806 | 0.0556 | 0.0762 | 0.7052 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 658 | 168 | | 403 | 1766 | 68.5 | 19.76 | 7.99 | 2.37 | 49 | 53 | 56 | 59 | 63 | 70 | 74 | 85 | 98 | 0.1750 | 309 | 1.167 | 34.83 | 13.34 | 1 | 0.2258 | 91 | 0.0533 | 1.76 | 3.525 | 0.6505 | 5083.4 | 408505 | 35400000 | 3290000000 | 0.4186 | 0.2106 | 0.0050 | 0.0000 | 0.0347 | 0.0029 | 0.1139 | 0.0233 | 0.1139 | 0.0437 | 0.1386 | 0.0962 | 0.1238 | 0.1895 | 0.1386 | 0.1137 | 0.1238 | 0.1429 | 0.2079 | 0.3878 | 0.0034 | 0.0000 | 0.0103 | 0.0000 | 0.0206 | 0.0052 | 0.0412 | 0.0129 | 0.1237 | 0.0722 | 0.1340 | 0.1727 | 0.0790 | 0.0851 | 0.0962 | 0.1134 | 0.4914 | 0.5387 | 0.0112 | 0.0000 | 0.0112 | 0.0000 | 0.0000 | 0.0667 | 0.1236 | 0.2444 | 0.1685 | 0.2222 | 0.2360 | 0.2667 | 0.0787 | 0.0222 | 0.1461 | 0.0667 | 0.2247 | 0.1111 | 0.0000 | 0.0000 | 0.0117 | 0.0526 | 0.1287 | 0.1988 | 0.0877 | 0.1345 | 0.3860 | 5 | 6 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0170 | 10.27 | 4.413 | 0.3266 | 69.5 | 648.007 | 6410.02 | 66817.3 | 0.4806 | 0.1782 | 0.0225 | 0.0013 | 0.0688 | 0.0040 | 0.1865 | 0.0092 | 0.2678 | 0.0257 | 0.2240 | 0.0870 | 0.1502 | 0.1087 | 0.0601 | 0.1963 | 0.0138 | 0.3057 | 0.0063 | 0.2622 | 0.0049 | 0.0000 | 0.0154 | 0.0018 | 0.0561 | 0.0054 | 0.0829 | 0.0127 | 0.1488 | 0.0647 | 0.1715 | 0.0810 | 0.1837 | 0.0906 | 0.2179 | 0.2502 | 0.1187 | 0.4937 | 0.1230 | 0.3869 | 0.2181 | 0.2993 | 0.2645 | 0.1314 | 0.1763 | 0.1314 | 0.1137 | 0.0292 | 0.0650 | 0.0219 | 0.0232 | 0.0000 | 0.0139 | 0.0000 | 0.0023 | 0.0000 | 0.0089 | 0.0445 | 0.0870 | 0.1235 | 0.1966 | 0.2184 | 0.1601 | 0.1235 | 0.0375 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1205 | 176 | | 372 | 2800 | 40.2 | 10.05 | 84.88 | 173.91 | 28 | 30 | 34 | 37 | 39 | 41 | 45 | 49 | 53 | 0.1139 | 319 | 0.581 | 191.64 | 52.00 | 2 | 1.5618 | 581 | 0.0086 | 8.20 | 4.933 | 0.3440 | 1713.9 | 77670.5 | 3730000 | 189000000 | 0.3953 | 0.2248 | 0.0051 | 0.0000 | 0.0154 | 0.0000 | 0.0359 | 0.0000 | 0.1333 | 0.0088 | 0.1744 | 0.0821 | 0.1897 | 0.0645 | 0.2154 | 0.1026 | 0.1333 | 0.1378 | 0.0974 | 0.6041 | 0.0036 | 0.0000 | 0.0108 | 0.0000 | 0.0108 | 0.0000 | 0.0502 | 0.0054 | 0.0681 | 0.0622 | 0.0681 | 0.0514 | 0.0968 | 0.0514 | 0.1147 | 0.0784 | 0.5771 | 0.7514 | 0.0000 | 0.0000 | 0.0357 | 0.0345 | 0.1190 | 0.0690 | 0.0238 | 0.2069 | 0.1786 | 0.1379 | 0.1667 | 0.0345 | 0.0952 | 0.2069 | 0.1548 | 0.1379 | 0.2262 | 0.1724 | 0.0056 | 0.0056 | 0.0222 | 0.0444 | 0.0778 | 0.0944 | 0.0889 | 0.1778 | 0.4833 | 15 | 17 | 19 | 21 | 23 | 27 | 32 | 79 | 241 | 0.2089 | 3.35 | 2.782 | 0.7521 | 37440.5 | 29600000 | 28700000000 | 30700000000000 | 0.7152 | 0.0493 | 0.0130 | 0.0061 | 0.1299 | 0.0242 | 0.2987 | 0.0242 | 0.1948 | 0.0848 | 0.1429 | 0.2061 | 0.0779 | 0.2485 | 0.0649 | 0.1333 | 0.0260 | 0.1455 | 0.0519 | 0.1273 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0047 | 0.0120 | 0.0126 | 0.0342 | 0.0346 | 0.0496 | 0.0362 | 0.0479 | 0.0472 | 0.0803 | 0.0849 | 0.7761 | 0.7799 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0021 | 0.0138 | 0.0085 | 0.0472 | 0.0446 | 0.0591 | 0.0807 | 0.0571 | 0.0573 | 0.1004 | 0.1083 | 0.7185 | 0.6985 | 0.0000 | 0.0000 | 0.0018 | 0.0091 | 0.0453 | 0.0507 | 0.0562 | 0.0888 | 0.7482 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 382 | 482 | | 6733 | 6438 | 43.2 | 12.21 | 112.41 | 165.59 | 28 | 32 | 35 | 39 | 42 | 46 | 50 | 54 | 60 | 0.1785 | 1149 | 1.039 | 54.34 | 16.16 | 3 | 0.0192 | 129 | 0.0360 | 0.84 | 3.592 | 0.6983 | 2014.6 | 100311 | 5270000 | 290000000 | 0.3887 | 0.2344 | 0.0060 | 0.0014 | 0.0139 | 0.0039 | 0.0220 | 0.0043 | 0.0460 | 0.0107 | 0.0794 | 0.0318 | 0.1389 | 0.0469 | 0.1480 | 0.0529 | 0.1880 | 0.0959 | 0.3578 | 0.7522 | 0.0027 | 0.0005 | 0.0041 | 0.0010 | 0.0078 | 0.0010 | 0.0188 | 0.0052 | 0.0347 | 0.0229 | 0.0580 | 0.0316 | 0.0586 | 0.0321 | 0.0858 | 0.0495 | 0.7295 | 0.8563 | 0.0070 | 0.0313 | 0.0186 | 0.0224 | 0.0256 | 0.0328 | 0.0413 | 0.0627 | 0.0721 | 0.0687 | 0.0809 | 0.1224 | 0.0878 | 0.1328 | 0.1268 | 0.1597 | 0.5398 | 0.3672 | 0.0033 | 0.0090 | 0.0189 | 0.0269 | 0.0452 | 0.0619 | 0.0736 | 0.0984 | 0.6628 | 7 | 8 | 10 | 12 | 19 | 48 | 124 | 221 | 345 | 0.0718 | 6.66 | 3.779 | 0.5031 | 40050.5 | 19600000 | 11300000000 | 7260000000000 | 0.4549 | 0.1859 | 0.0359 | 0.0046 | 0.1257 | 0.0170 | 0.2036 | 0.0880 | 0.1916 | 0.1173 | 0.1796 | 0.1867 | 0.1168 | 0.1929 | 0.0778 | 0.1312 | 0.0539 | 0.1281 | 0.0150 | 0.1343 | 0.0005 | 0.0008 | 0.0014 | 0.0021 | 0.0023 | 0.0008 | 0.0087 | 0.0068 | 0.0407 | 0.0343 | 0.0535 | 0.0525 | 0.0512 | 0.0423 | 0.0699 | 0.0728 | 0.7719 | 0.7875 | 0.0005 | 0.0000 | 0.0000 | 0.0012 | 0.0022 | 0.0041 | 0.0097 | 0.0146 | 0.0529 | 0.0578 | 0.0707 | 0.0776 | 0.0723 | 0.0712 | 0.0960 | 0.0968 | 0.6958 | 0.6768 | 0.0000 | 0.0010 | 0.0035 | 0.0144 | 0.0416 | 0.0575 | 0.0615 | 0.0878 | 0.7328 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1199 | 461 | | 4972 | 6147 | 193.3 | 101.39 | 92.03 | 198.27 | 86 | 103 | 120 | 137 | 155 | 189 | 252 | 298 | 348 | 0.1223 | 752 | 0.646 | 151.35 | 28.23 | 6 | 0.0686 | 341 | 0.0019 | 14.93 | 6.742 | 0.3352 | 47639.3 | 13900000 | 4520000000 | 1570000000000 | 0.3496 | 0.2649 | 0.0060 | 0.0004 | 0.0048 | 0.0035 | 0.0132 | 0.0052 | 0.0396 | 0.0148 | 0.1321 | 0.0461 | 0.2233 | 0.0804 | 0.1417 | 0.0722 | 0.1573 | 0.1039 | 0.2821 | 0.6735 | 0.0016 | 0.0003 | 0.0016 | 0.0017 | 0.0036 | 0.0011 | 0.0084 | 0.0058 | 0.0244 | 0.0172 | 0.0407 | 0.0302 | 0.0339 | 0.0266 | 0.0395 | 0.0388 | 0.8462 | 0.8784 | 0.0000 | 0.0008 | 0.0006 | 0.0015 | 0.0012 | 0.0061 | 0.0096 | 0.0107 | 0.0215 | 0.0313 | 0.0413 | 0.0595 | 0.0311 | 0.0489 | 0.0431 | 0.0794 | 0.8516 | 0.7618 | 0.0005 | 0.0000 | 0.0005 | 0.0046 | 0.0245 | 0.0408 | 0.0245 | 0.0362 | 0.8684 | 6 | 7 | 9 | 10 | 13 | 18 | 35 | 93 | 274 | 0.1539 | 10.11 | 3.626 | 0.6621 | 47772.6 | 36200000 | 31300000000 | 29200000000000 | 0.4667 | 0.1877 | 0.0120 | 0.0059 | 0.0518 | 0.0098 | 0.1076 | 0.0234 | 0.1992 | 0.0508 | 0.2231 | 0.1484 | 0.1673 | 0.2266 | 0.0916 | 0.1348 | 0.0598 | 0.1465 | 0.0876 | 0.2539 | 0.0007 | 0.0013 | 0.0036 | 0.0026 | 0.0051 | 0.0078 | 0.0182 | 0.0156 | 0.0547 | 0.0591 | 0.0591 | 0.0604 | 0.0562 | 0.0558 | 0.0795 | 0.0734 | 0.7228 | 0.7240 | 0.0000 | 0.0010 | 0.0063 | 0.0019 | 0.0063 | 0.0039 | 0.0116 | 0.0068 | 0.0634 | 0.0623 | 0.0598 | 0.0700 | 0.0625 | 0.0623 | 0.0938 | 0.0944 | 0.6964 | 0.6975 | 0.0008 | 0.0041 | 0.0081 | 0.0122 | 0.0575 | 0.0632 | 0.0624 | 0.0875 | 0.7042 |