High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 533 | 682 | 7313 | 29998 | 383.9 | 96.67 | 156.93 | 277.72 | 269 | 302 | 327 | 350 | 372 | 397 | 429 | 467 | 513 | 0.0399 | 1198 | 1.208 | 132.80 | 56.82 | 1 | 0.0483 | 353 | 0.0008 | 42.70 | 7.362 | 0.1796 | 156719.0 | 67700000 | 30900000000 | 14700000000000 | 0.4294 | 0.2186 | 0.0000 | 0.0002 | 0.0019 | 0.0000 | 0.0056 | 0.0006 | 0.0223 | 0.0032 | 0.0776 | 0.0240 | 0.1395 | 0.0531 | 0.1380 | 0.0451 | 0.1584 | 0.0649 | 0.4567 | 0.8089 | 0.0000 | 0.0001 | 0.0011 | 0.0000 | 0.0023 | 0.0003 | 0.0074 | 0.0016 | 0.0342 | 0.0155 | 0.0598 | 0.0314 | 0.0600 | 0.0208 | 0.0798 | 0.0327 | 0.7556 | 0.8977 | 0.0032 | 0.0056 | 0.0051 | 0.0093 | 0.0051 | 0.0075 | 0.0329 | 0.0746 | 0.0981 | 0.1362 | 0.1253 | 0.2034 | 0.1101 | 0.1063 | 0.1380 | 0.1716 | 0.4823 | 0.2854 | 0.0003 | 0.0015 | 0.0075 | 0.0301 | 0.0733 | 0.1004 | 0.0869 | 0.1025 | 0.5975 | 8 | 9 | 11 | 12 | 15 | 25 | 92 | 285 | 569 | 0.2355 | 33.94 | 3.958 | 0.6313 | 101753.0 | 91200000 | 98600000000 | 124000000000000 | 0.4779 | 0.1557 | 0.1073 | 0.0081 | 0.3320 | 0.0585 | 0.3330 | 0.2590 | 0.1394 | 0.2001 | 0.0471 | 0.2020 | 0.0301 | 0.1388 | 0.0090 | 0.0741 | 0.0020 | 0.0371 | 0.0000 | 0.0223 | 0.0002 | 0.0004 | 0.0006 | 0.0011 | 0.0008 | 0.0010 | 0.0076 | 0.0093 | 0.0425 | 0.0390 | 0.0726 | 0.0654 | 0.0486 | 0.0443 | 0.0803 | 0.0682 | 0.7467 | 0.7711 | 0.0001 | 0.0001 | 0.0004 | 0.0000 | 0.0019 | 0.0013 | 0.0107 | 0.0116 | 0.0477 | 0.0518 | 0.0894 | 0.1012 | 0.0658 | 0.0667 | 0.0972 | 0.1078 | 0.6868 | 0.6595 | 0.0000 | 0.0005 | 0.0009 | 0.0099 | 0.0457 | 0.0788 | 0.0566 | 0.0902 | 0.7173 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1013 | 776 | 4132 | 4149 | 163.6 | 45.21 | 162.20 | 159.12 | 116 | 127 | 136 | 145 | 155 | 166 | 178 | 197 | 224 | 0.1347 | 559 | 1.127 | 94.07 | 29.83 | 1 | 0.0549 | 227 | 0.0016 | 35.59 | 6.765 | 0.2144 | 28795.0 | 5490000 | 1140000000 | 256000000000 | 0.3736 | 0.2711 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0097 | 0.0000 | 0.0313 | 0.0016 | 0.1031 | 0.0289 | 0.1793 | 0.0586 | 0.1696 | 0.0559 | 0.1608 | 0.0805 | 0.3449 | 0.7744 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0000 | 0.0126 | 0.0012 | 0.0426 | 0.0173 | 0.0765 | 0.0318 | 0.0726 | 0.0202 | 0.0833 | 0.0333 | 0.7089 | 0.8961 | 0.0012 | 0.0057 | 0.0060 | 0.0028 | 0.0193 | 0.0342 | 0.0712 | 0.1026 | 0.1351 | 0.1852 | 0.1689 | 0.1538 | 0.1074 | 0.1254 | 0.1544 | 0.1282 | 0.3366 | 0.2621 | 0.0006 | 0.0029 | 0.0081 | 0.0400 | 0.0737 | 0.1398 | 0.0986 | 0.1119 | 0.5244 | 19 | 39 | 59 | 79 | 105 | 140 | 187 | 267 | 405 | 0.0058 | 51.95 | 6.395 | 0.3274 | 51621.9 | 23000000 | 12200000000 | 7280000000000 | 0.4555 | 0.1933 | 0.0214 | 0.0008 | 0.1246 | 0.0084 | 0.2206 | 0.0489 | 0.1851 | 0.1281 | 0.1495 | 0.1778 | 0.1388 | 0.1912 | 0.0747 | 0.1272 | 0.0534 | 0.1348 | 0.0320 | 0.1828 | 0.0006 | 0.0000 | 0.0011 | 0.0036 | 0.0034 | 0.0027 | 0.0238 | 0.0173 | 0.0747 | 0.0600 | 0.1065 | 0.1055 | 0.0821 | 0.0673 | 0.1121 | 0.1014 | 0.5957 | 0.6421 | 0.0017 | 0.0000 | 0.0033 | 0.0040 | 0.0083 | 0.0049 | 0.0282 | 0.0346 | 0.0698 | 0.0949 | 0.1412 | 0.1215 | 0.0947 | 0.1057 | 0.1204 | 0.1364 | 0.5324 | 0.4980 | 0.0007 | 0.0034 | 0.0103 | 0.0248 | 0.0765 | 0.1254 | 0.0827 | 0.1158 | 0.5603 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 121 | 590 | 6826 | 22797 | 692.3 | 141.16 | 184.25 | 147.65 | 524 | 569 | 603 | 636 | 672 | 711 | 754 | 812 | 894 | 0.0504 | 1149 | 1.195 | 96.01 | 36.50 | 1 | 0.0355 | 242 | 0.0006 | 74.81 | 7.679 | 0.1333 | 499160.0 | 375000000 | 293000000000 | 238000000000000 | 0.4097 | 0.2333 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0033 | 0.0000 | 0.0134 | 0.0015 | 0.0541 | 0.0141 | 0.1179 | 0.0327 | 0.1221 | 0.0242 | 0.1447 | 0.0447 | 0.5439 | 0.8825 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0054 | 0.0001 | 0.0244 | 0.0100 | 0.0560 | 0.0208 | 0.0529 | 0.0091 | 0.0796 | 0.0171 | 0.7802 | 0.9428 | 0.0000 | 0.0210 | 0.0059 | 0.0385 | 0.0245 | 0.0559 | 0.0422 | 0.0594 | 0.1114 | 0.1713 | 0.1401 | 0.1608 | 0.1241 | 0.1014 | 0.1595 | 0.1399 | 0.3924 | 0.2517 | 0.0007 | 0.0033 | 0.0052 | 0.0244 | 0.0711 | 0.1157 | 0.0949 | 0.1252 | 0.5596 | 31 | 53 | 80 | 111 | 147 | 188 | 236 | 298 | 396 | 0.0053 | 17.90 | 6.140 | 0.3553 | 55747.2 | 22400000 | 11300000000 | 7040000000000 | 0.4802 | 0.1654 | 0.0189 | 0.0009 | 0.1045 | 0.0065 | 0.1943 | 0.0481 | 0.1712 | 0.0929 | 0.1772 | 0.1570 | 0.1568 | 0.1982 | 0.0804 | 0.1530 | 0.0592 | 0.1463 | 0.0375 | 0.1971 | 0.0006 | 0.0003 | 0.0018 | 0.0010 | 0.0062 | 0.0037 | 0.0214 | 0.0144 | 0.0636 | 0.0533 | 0.1041 | 0.0946 | 0.0826 | 0.0723 | 0.1081 | 0.1001 | 0.6117 | 0.6604 | 0.0021 | 0.0022 | 0.0055 | 0.0077 | 0.0141 | 0.0176 | 0.0366 | 0.0471 | 0.0854 | 0.0843 | 0.1155 | 0.1211 | 0.0905 | 0.0961 | 0.1101 | 0.1108 | 0.5402 | 0.5131 | 0.0011 | 0.0033 | 0.0088 | 0.0271 | 0.0757 | 0.1130 | 0.0967 | 0.1074 | 0.5670 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 819 | 741 | 5979 | 6896 | 220.8 | 55.20 | 179.58 | 138.54 | 160 | 176 | 189 | 201 | 212 | 224 | 239 | 259 | 290 | 0.1115 | 769 | 1.055 | 105.12 | 32.02 | 1 | 0.0418 | 250 | 0.0010 | 54.65 | 7.224 | 0.1685 | 51796.9 | 13000000 | 3490000000 | 1010000000000 | 0.4435 | 0.2077 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0040 | 0.0000 | 0.0187 | 0.0015 | 0.0749 | 0.0195 | 0.1570 | 0.0462 | 0.1484 | 0.0436 | 0.1840 | 0.0676 | 0.4128 | 0.8214 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0000 | 0.0059 | 0.0002 | 0.0381 | 0.0134 | 0.0733 | 0.0232 | 0.0677 | 0.0209 | 0.1008 | 0.0375 | 0.7133 | 0.9047 | 0.0048 | 0.0024 | 0.0107 | 0.0000 | 0.0213 | 0.0095 | 0.0804 | 0.0735 | 0.1231 | 0.1659 | 0.1841 | 0.2109 | 0.0940 | 0.0948 | 0.1260 | 0.1469 | 0.3556 | 0.2962 | 0.0016 | 0.0020 | 0.0102 | 0.0317 | 0.0939 | 0.1412 | 0.1146 | 0.1451 | 0.4597 | 35 | 59 | 83 | 111 | 142 | 182 | 230 | 292 | 373 | 0.0020 | 58.17 | 6.937 | 0.2558 | 51437.9 | 19300000 | 8700000000 | 4480000000000 | 0.5354 | 0.1275 | 0.0234 | 0.0012 | 0.1292 | 0.0079 | 0.2559 | 0.0540 | 0.1882 | 0.1092 | 0.1683 | 0.1926 | 0.1110 | 0.1934 | 0.0642 | 0.1357 | 0.0399 | 0.1274 | 0.0199 | 0.1785 | 0.0000 | 0.0000 | 0.0012 | 0.0007 | 0.0041 | 0.0040 | 0.0199 | 0.0119 | 0.0809 | 0.0632 | 0.1232 | 0.1038 | 0.0870 | 0.0722 | 0.1300 | 0.1109 | 0.5537 | 0.6333 | 0.0022 | 0.0006 | 0.0018 | 0.0033 | 0.0106 | 0.0155 | 0.0343 | 0.0472 | 0.1004 | 0.1210 | 0.1612 | 0.1805 | 0.1233 | 0.1260 | 0.1440 | 0.1460 | 0.4223 | 0.3598 | 0.0018 | 0.0029 | 0.0068 | 0.0310 | 0.0863 | 0.1320 | 0.1059 | 0.1469 | 0.4864 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 917 | 765 | 4787 | 6025 | 134.0 | 29.36 | 199.47 | 144.31 | 101 | 111 | 117 | 124 | 130 | 137 | 145 | 154 | 168 | 0.1200 | 723 | 1.159 | 112.49 | 39.01 | 1 | 0.0570 | 273 | 0.0026 | 20.01 | 6.253 | 0.2547 | 18810.6 | 2780000 | 434000000 | 72000000000 | 0.4427 | 0.2093 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0064 | 0.0013 | 0.0155 | 0.0016 | 0.0709 | 0.0202 | 0.1267 | 0.0377 | 0.1506 | 0.0388 | 0.1815 | 0.0566 | 0.4467 | 0.8438 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0073 | 0.0004 | 0.0405 | 0.0149 | 0.0653 | 0.0246 | 0.0710 | 0.0181 | 0.0965 | 0.0305 | 0.7169 | 0.9114 | 0.0043 | 0.0000 | 0.0157 | 0.0082 | 0.0443 | 0.0286 | 0.0944 | 0.1224 | 0.1688 | 0.1510 | 0.1574 | 0.2041 | 0.0987 | 0.1102 | 0.1273 | 0.1224 | 0.2890 | 0.2531 | 0.0018 | 0.0042 | 0.0125 | 0.0365 | 0.0983 | 0.1347 | 0.1117 | 0.1440 | 0.4564 | 44 | 68 | 100 | 134 | 171 | 211 | 256 | 309 | 392 | 0.0015 | 70.67 | 7.066 | 0.2195 | 60610.6 | 23900000 | 11300000000 | 6160000000000 | 0.5305 | 0.1272 | 0.0202 | 0.0004 | 0.0960 | 0.0047 | 0.2098 | 0.0436 | 0.2030 | 0.0781 | 0.1955 | 0.1872 | 0.1348 | 0.1919 | 0.0851 | 0.1725 | 0.0447 | 0.1552 | 0.0110 | 0.1665 | 0.0006 | 0.0003 | 0.0009 | 0.0005 | 0.0019 | 0.0026 | 0.0206 | 0.0127 | 0.0768 | 0.0560 | 0.1070 | 0.0915 | 0.0989 | 0.0710 | 0.1385 | 0.1099 | 0.5548 | 0.6556 | 0.0015 | 0.0032 | 0.0064 | 0.0097 | 0.0124 | 0.0175 | 0.0500 | 0.0662 | 0.1199 | 0.1364 | 0.1640 | 0.1857 | 0.1189 | 0.1422 | 0.1690 | 0.1513 | 0.3578 | 0.2877 | 0.0008 | 0.0008 | 0.0077 | 0.0291 | 0.0926 | 0.1403 | 0.1170 | 0.1592 | 0.4525 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1240 | 782 | 5520 | 5479 | 133.2 | 23.75 | 110.66 | 100.88 | 104 | 113 | 119 | 126 | 132 | 138 | 144 | 152 | 163 | 0.1374 | 753 | 0.999 | 91.29 | 24.70 | 1 | 0.0397 | 219 | 0.0031 | 14.38 | 6.066 | 0.2851 | 18294.8 | 2590000 | 379000000 | 57200000000 | 0.4125 | 0.2388 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0002 | 0.0212 | 0.0007 | 0.0442 | 0.0156 | 0.0934 | 0.0282 | 0.1204 | 0.0252 | 0.1646 | 0.0404 | 0.5507 | 0.8897 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0083 | 0.0002 | 0.0228 | 0.0129 | 0.0452 | 0.0203 | 0.0504 | 0.0132 | 0.0765 | 0.0234 | 0.7949 | 0.9300 | 0.0226 | 0.0169 | 0.0155 | 0.0763 | 0.0523 | 0.1102 | 0.1088 | 0.1102 | 0.1638 | 0.1525 | 0.1723 | 0.2034 | 0.1201 | 0.1356 | 0.1554 | 0.0847 | 0.1893 | 0.1102 | 0.0033 | 0.0089 | 0.0118 | 0.0380 | 0.0687 | 0.1048 | 0.1063 | 0.1384 | 0.5197 | 27 | 36 | 47 | 60 | 75 | 95 | 123 | 168 | 249 | 0.0062 | 29.53 | 5.971 | 0.3642 | 22419.6 | 6640000 | 2430000000 | 1010000000000 | 0.6287 | 0.0903 | 0.0259 | 0.0043 | 0.1147 | 0.0103 | 0.2160 | 0.0511 | 0.1732 | 0.0983 | 0.1395 | 0.1836 | 0.1192 | 0.1825 | 0.0934 | 0.1477 | 0.0742 | 0.1266 | 0.0439 | 0.1955 | 0.0017 | 0.0020 | 0.0034 | 0.0039 | 0.0089 | 0.0098 | 0.0326 | 0.0219 | 0.0852 | 0.0732 | 0.1360 | 0.1023 | 0.1004 | 0.0859 | 0.1513 | 0.1366 | 0.4805 | 0.5644 | 0.0020 | 0.0025 | 0.0095 | 0.0033 | 0.0102 | 0.0172 | 0.0428 | 0.0582 | 0.1292 | 0.1534 | 0.1747 | 0.1838 | 0.1237 | 0.1017 | 0.1475 | 0.1403 | 0.3603 | 0.3396 | 0.0016 | 0.0064 | 0.0155 | 0.0321 | 0.1095 | 0.1474 | 0.1239 | 0.1394 | 0.4241 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 352 | 145 | 6842 | 23190 | 516.1 | 88.93 | 82.73 | 76.82 | 394 | 442 | 473 | 497 | 519 | 540 | 560 | 588 | 626 | 0.0471 | 1092 | 1.217 | 112.40 | 44.05 | 1 | 0.0417 | 285 | 0.0008 | 51.79 | 7.367 | 0.1654 | 274282.0 | 150000000 | 83800000000 | 48000000000000 | 0.4133 | 0.2357 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0068 | 0.0009 | 0.0395 | 0.0128 | 0.0867 | 0.0244 | 0.0880 | 0.0204 | 0.1257 | 0.0318 | 0.6515 | 0.9098 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0001 | 0.0219 | 0.0112 | 0.0469 | 0.0212 | 0.0429 | 0.0121 | 0.0560 | 0.0240 | 0.8305 | 0.9315 | 0.0064 | 0.0000 | 0.0244 | 0.0385 | 0.0450 | 0.1538 | 0.0720 | 0.1795 | 0.1362 | 0.1538 | 0.1542 | 0.1923 | 0.1105 | 0.1538 | 0.1041 | 0.0769 | 0.3470 | 0.0513 | 0.0006 | 0.0014 | 0.0071 | 0.0246 | 0.0801 | 0.1194 | 0.1251 | 0.1398 | 0.5020 | 13 | 21 | 33 | 47 | 63 | 80 | 100 | 127 | 174 | 0.0136 | 7.65 | 5.221 | 0.4945 | 12746.0 | 3030000 | 998000000 | 416000000000 | 0.4776 | 0.1511 | 0.0127 | 0.0009 | 0.0661 | 0.0029 | 0.1634 | 0.0253 | 0.1896 | 0.0621 | 0.2119 | 0.1354 | 0.1531 | 0.1850 | 0.1031 | 0.1644 | 0.0654 | 0.1703 | 0.0348 | 0.2537 | 0.0006 | 0.0001 | 0.0017 | 0.0006 | 0.0053 | 0.0027 | 0.0178 | 0.0129 | 0.0589 | 0.0423 | 0.0902 | 0.0637 | 0.0775 | 0.0651 | 0.1124 | 0.0898 | 0.6356 | 0.7229 | 0.0024 | 0.0026 | 0.0024 | 0.0051 | 0.0088 | 0.0130 | 0.0336 | 0.0403 | 0.0825 | 0.0987 | 0.1329 | 0.1479 | 0.1037 | 0.1076 | 0.1323 | 0.1377 | 0.5013 | 0.4472 | 0.0009 | 0.0038 | 0.0065 | 0.0246 | 0.0676 | 0.1127 | 0.0949 | 0.1192 | 0.5699 | |||
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 576 | 951 | 438 | 2028 | 54.0 | 7.53 | 156.62 | 225.49 | 45 | 48 | 49 | 51 | 54 | 55 | 57 | 60 | 63 | 0.1686 | 342 | 0.895 | 78.01 | 22.20 | 1 | 0.4566 | 200 | 0.0096 | 10.55 | 4.855 | 0.3142 | 2971.3 | 166797 | 9560000 | 559000000 | 0.3875 | 0.2379 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0023 | 0.0262 | 0.0092 | 0.0945 | 0.0624 | 0.1260 | 0.0901 | 0.1811 | 0.0693 | 0.2520 | 0.1085 | 0.3123 | 0.6582 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0023 | 0.0193 | 0.0091 | 0.0578 | 0.0594 | 0.0988 | 0.0868 | 0.1012 | 0.0548 | 0.1518 | 0.0868 | 0.5639 | 0.7009 | 0.1765 | 0.0000 | 0.1765 | 0.2000 | 0.0588 | 0.2000 | 0.1765 | 0.6000 | 0.1176 | 0.0000 | 0.0294 | 0.0000 | 0.1765 | 0.0000 | 0.0882 | 0.0000 | 0.0000 | 0.0000 | 0.0136 | 0.0318 | 0.0227 | 0.0773 | 0.1364 | 0.1364 | 0.1500 | 0.2091 | 0.2227 | 17 | 21 | 28 | 41 | 64 | 99 | 142 | 241 | 425 | 0.0260 | 58.20 | 5.100 | 0.4350 | 75349.7 | 58100000 | 55000000000 | 57800000000000 | 0.4831 | 0.1439 | 0.1056 | 0.0000 | 0.2609 | 0.0221 | 0.2050 | 0.1838 | 0.0870 | 0.1569 | 0.1242 | 0.1936 | 0.0870 | 0.1201 | 0.0683 | 0.0760 | 0.0435 | 0.1176 | 0.0186 | 0.1299 | 0.0030 | 0.0000 | 0.0030 | 0.0036 | 0.0151 | 0.0059 | 0.0256 | 0.0119 | 0.0935 | 0.0973 | 0.1704 | 0.1269 | 0.0905 | 0.0973 | 0.1297 | 0.1329 | 0.4691 | 0.5243 | 0.0020 | 0.0000 | 0.0060 | 0.0069 | 0.0159 | 0.0207 | 0.0239 | 0.0345 | 0.1076 | 0.1310 | 0.1853 | 0.1816 | 0.1036 | 0.0989 | 0.1474 | 0.1402 | 0.4084 | 0.3862 | 0.0000 | 0.0035 | 0.0159 | 0.0265 | 0.1044 | 0.1805 | 0.0973 | 0.1274 | 0.4442 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 634 | 828 | 6200 | 7303 | 203.7 | 43.18 | 209.83 | 149.65 | 154 | 167 | 178 | 188 | 198 | 208 | 221 | 237 | 262 | 0.1191 | 870 | 1.113 | 92.59 | 26.68 | 1 | 0.0353 | 219 | 0.0012 | 41.78 | 7.014 | 0.1838 | 43340.5 | 9650000 | 2250000000 | 547000000000 | 0.4334 | 0.2122 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0031 | 0.0003 | 0.0157 | 0.0007 | 0.0711 | 0.0174 | 0.1256 | 0.0376 | 0.1517 | 0.0398 | 0.1830 | 0.0615 | 0.4490 | 0.8428 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0002 | 0.0066 | 0.0000 | 0.0335 | 0.0122 | 0.0534 | 0.0229 | 0.0720 | 0.0143 | 0.0964 | 0.0265 | 0.7359 | 0.9239 | 0.0059 | 0.0102 | 0.0088 | 0.0307 | 0.0137 | 0.0648 | 0.0715 | 0.1160 | 0.1538 | 0.1945 | 0.1851 | 0.1672 | 0.1303 | 0.1297 | 0.1538 | 0.1229 | 0.2772 | 0.1638 | 0.0025 | 0.0040 | 0.0087 | 0.0395 | 0.0938 | 0.1242 | 0.1177 | 0.1409 | 0.4687 | 40 | 70 | 103 | 137 | 177 | 225 | 280 | 343 | 426 | 0.0014 | 93.66 | 7.304 | 0.1920 | 66420.4 | 25900000 | 11500000000 | 5580000000000 | 0.5796 | 0.1202 | 0.0390 | 0.0023 | 0.1851 | 0.0148 | 0.2695 | 0.0760 | 0.1802 | 0.1442 | 0.1420 | 0.1832 | 0.1063 | 0.2186 | 0.0446 | 0.1454 | 0.0219 | 0.1134 | 0.0114 | 0.1021 | 0.0005 | 0.0007 | 0.0029 | 0.0009 | 0.0084 | 0.0050 | 0.0260 | 0.0176 | 0.0825 | 0.0686 | 0.1372 | 0.1114 | 0.1075 | 0.0997 | 0.1319 | 0.1233 | 0.5030 | 0.5729 | 0.0019 | 0.0034 | 0.0051 | 0.0059 | 0.0179 | 0.0206 | 0.0451 | 0.0677 | 0.1147 | 0.1290 | 0.1683 | 0.1986 | 0.1306 | 0.1226 | 0.1446 | 0.1466 | 0.3719 | 0.3055 | 0.0003 | 0.0064 | 0.0121 | 0.0359 | 0.0978 | 0.1547 | 0.1134 | 0.1556 | 0.4239 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 317 | 690 | 3464 | 11834 | 342.0 | 75.63 | 178.33 | 204.51 | 250 | 275 | 296 | 316 | 334 | 353 | 374 | 407 | 449 | 0.0724 | 857 | 0.954 | 122.41 | 43.14 | 1 | 0.0944 | 327 | 0.0010 | 39.91 | 7.112 | 0.1793 | 122696.0 | 46100000 | 18100000000 | 7380000000000 | 0.3949 | 0.2434 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0033 | 0.0000 | 0.0135 | 0.0025 | 0.0652 | 0.0246 | 0.1226 | 0.0467 | 0.1086 | 0.0418 | 0.1407 | 0.0563 | 0.5461 | 0.8278 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0061 | 0.0015 | 0.0275 | 0.0178 | 0.0582 | 0.0338 | 0.0453 | 0.0228 | 0.0735 | 0.0336 | 0.7874 | 0.8906 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0061 | 0.0000 | 0.0350 | 0.0000 | 0.1035 | 0.0000 | 0.1461 | 0.0000 | 0.0989 | 0.0000 | 0.1370 | 0.0000 | 0.4718 | 0.0000 | 0.0006 | 0.0025 | 0.0063 | 0.0151 | 0.0753 | 0.0834 | 0.0997 | 0.1173 | 0.5997 | 15 | 19 | 31 | 55 | 87 | 145 | 230 | 323 | 470 | 0.0227 | 19.50 | 5.564 | 0.4886 | 73621.5 | 41900000 | 28500000000 | 21900000000000 | 0.6117 | 0.0866 | 0.0329 | 0.0009 | 0.1078 | 0.0038 | 0.2187 | 0.0509 | 0.1920 | 0.0937 | 0.1694 | 0.1715 | 0.1283 | 0.2068 | 0.0688 | 0.1413 | 0.0431 | 0.1328 | 0.0390 | 0.1983 | 0.0002 | 0.0002 | 0.0004 | 0.0002 | 0.0017 | 0.0009 | 0.0090 | 0.0061 | 0.0363 | 0.0348 | 0.0722 | 0.0563 | 0.0539 | 0.0445 | 0.0705 | 0.0661 | 0.7557 | 0.7909 | 0.0003 | 0.0006 | 0.0018 | 0.0012 | 0.0021 | 0.0033 | 0.0127 | 0.0169 | 0.0496 | 0.0586 | 0.0939 | 0.1112 | 0.0702 | 0.0843 | 0.0915 | 0.0991 | 0.6779 | 0.6248 | 0.0000 | 0.0007 | 0.0017 | 0.0106 | 0.0439 | 0.0866 | 0.0599 | 0.0792 | 0.7175 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1211 | 757 | 6987 | 17413 | 330.1 | 42.49 | 131.75 | 174.14 | 277 | 295 | 309 | 320 | 331 | 341 | 352 | 366 | 384 | 0.0637 | 1110 | 0.875 | 72.84 | 16.16 | 1 | 0.0238 | 166 | 0.0022 | 16.55 | 6.447 | 0.2611 | 110777.0 | 37800000 | 13100000000 | 4580000000000 | 0.4400 | 0.2087 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0062 | 0.0000 | 0.0213 | 0.0109 | 0.0321 | 0.0178 | 0.0485 | 0.0100 | 0.0745 | 0.0186 | 0.8160 | 0.9427 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0000 | 0.0128 | 0.0109 | 0.0169 | 0.0178 | 0.0198 | 0.0095 | 0.0305 | 0.0166 | 0.9167 | 0.9453 | 0.0122 | 0.0000 | 0.0389 | 1.0000 | 0.0681 | 0.0000 | 0.1387 | 0.0000 | 0.1363 | 0.0000 | 0.1533 | 0.0000 | 0.1314 | 0.0000 | 0.1265 | 0.0000 | 0.1946 | 0.0000 | 0.0017 | 0.0047 | 0.0111 | 0.0255 | 0.0505 | 0.0813 | 0.0921 | 0.1160 | 0.6171 | 11 | 14 | 16 | 20 | 45 | 85 | 148 | 242 | 391 | 0.0761 | 18.56 | 4.883 | 0.5466 | 47679.7 | 24000000 | 14300000000 | 9510000000000 | 0.5710 | 0.1004 | 0.0354 | 0.0022 | 0.1286 | 0.0170 | 0.1973 | 0.0815 | 0.1517 | 0.1130 | 0.1402 | 0.1735 | 0.1156 | 0.1590 | 0.0860 | 0.1101 | 0.0744 | 0.1093 | 0.0708 | 0.2342 | 0.0002 | 0.0003 | 0.0005 | 0.0013 | 0.0017 | 0.0015 | 0.0103 | 0.0083 | 0.0444 | 0.0392 | 0.0713 | 0.0616 | 0.0547 | 0.0447 | 0.0799 | 0.0686 | 0.7370 | 0.7746 | 0.0002 | 0.0007 | 0.0022 | 0.0016 | 0.0044 | 0.0034 | 0.0156 | 0.0158 | 0.0577 | 0.0657 | 0.0944 | 0.1062 | 0.0716 | 0.0725 | 0.0954 | 0.1069 | 0.6586 | 0.6274 | 0.0004 | 0.0009 | 0.0034 | 0.0130 | 0.0497 | 0.0852 | 0.0639 | 0.0887 | 0.6949 | |
MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 524 | 141 | 4317 | 6246 | 463.8 | 114.50 | 71.69 | 106.41 | 339 | 369 | 392 | 415 | 440 | 467 | 500 | 549 | 629 | 0.1005 | 628 | 1.211 | 95.02 | 37.48 | 1 | 0.0563 | 243 | 0.0011 | 40.02 | 7.058 | 0.1884 | 228193.0 | 119000000 | 66600000000 | 39500000000000 | 0.3905 | 0.2504 | 0.0000 | 0.0000 | 0.0012 | 0.0005 | 0.0054 | 0.0005 | 0.0173 | 0.0033 | 0.0695 | 0.0228 | 0.1245 | 0.0415 | 0.1318 | 0.0400 | 0.1690 | 0.0488 | 0.4814 | 0.8426 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0000 | 0.0076 | 0.0009 | 0.0334 | 0.0140 | 0.0577 | 0.0244 | 0.0633 | 0.0147 | 0.0882 | 0.0216 | 0.7466 | 0.9244 | 0.0037 | 0.0000 | 0.0049 | 0.0057 | 0.0099 | 0.0345 | 0.0469 | 0.0690 | 0.0877 | 0.1293 | 0.1395 | 0.1264 | 0.1025 | 0.1264 | 0.1173 | 0.1494 | 0.4877 | 0.3592 | 0.0006 | 0.0051 | 0.0130 | 0.0395 | 0.0745 | 0.1072 | 0.0874 | 0.0987 | 0.5742 | 7 | 10 | 12 | 15 | 21 | 31 | 56 | 127 | 227 | 0.0902 | 12.13 | 4.224 | 0.6055 | 16459.4 | 5640000 | 2380000000 | 1160000000000 | 0.4828 | 0.1513 | 0.0532 | 0.0047 | 0.1894 | 0.0235 | 0.2990 | 0.0691 | 0.2359 | 0.1821 | 0.1196 | 0.2323 | 0.0698 | 0.2276 | 0.0266 | 0.1366 | 0.0000 | 0.0754 | 0.0066 | 0.0487 | 0.0000 | 0.0014 | 0.0000 | 0.0014 | 0.0022 | 0.0039 | 0.0129 | 0.0082 | 0.0533 | 0.0488 | 0.0787 | 0.0768 | 0.0566 | 0.0497 | 0.0981 | 0.0888 | 0.6983 | 0.7209 | 0.0000 | 0.0000 | 0.0013 | 0.0021 | 0.0058 | 0.0077 | 0.0154 | 0.0112 | 0.0624 | 0.0732 | 0.0977 | 0.0962 | 0.0585 | 0.0635 | 0.1145 | 0.1123 | 0.6444 | 0.6339 | 0.0000 | 0.0018 | 0.0035 | 0.0183 | 0.0589 | 0.0796 | 0.0654 | 0.0961 | 0.6765 | |||
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 508 | 386 | 1856 | 6121 | 930.2 | 328.29 | 7.48 | 2.44 | 554 | 653 | 741 | 809 | 938 | 1045 | 1136 | 1227 | 1377 | 0.0853 | 522 | 1.026 | 43.86 | 14.14 | 1 | 0.0641 | 119 | 0.0008 | 115.28 | 7.271 | 0.1207 | 972996.0 | 1100000000 | 1310000000000 | 1.62E+15 | 0.4447 | 0.1728 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0173 | 0.0007 | 0.0317 | 0.0064 | 0.1400 | 0.0443 | 0.2107 | 0.1180 | 0.1486 | 0.0730 | 0.1962 | 0.1001 | 0.2554 | 0.6574 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0006 | 0.0093 | 0.0030 | 0.0388 | 0.0270 | 0.0705 | 0.0642 | 0.0496 | 0.0354 | 0.0659 | 0.0564 | 0.7651 | 0.8134 | 0.0034 | 0.0000 | 0.0000 | 0.0074 | 0.0000 | 0.0037 | 0.0201 | 0.0260 | 0.0586 | 0.1078 | 0.1273 | 0.1933 | 0.0771 | 0.0818 | 0.1039 | 0.0855 | 0.6097 | 0.4944 | 0.0000 | 0.0000 | 0.0000 | 0.0053 | 0.0427 | 0.0907 | 0.0491 | 0.0768 | 0.7353 | 5 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0178 | 7.81 | 4.411 | 0.3613 | 61.9 | 562.793 | 5603.58 | 60707.4 | 0.4721 | 0.1687 | 0.0133 | 0.0031 | 0.0511 | 0.0061 | 0.1011 | 0.0157 | 0.1867 | 0.0367 | 0.2357 | 0.0887 | 0.1933 | 0.1507 | 0.1532 | 0.2219 | 0.0544 | 0.2907 | 0.0113 | 0.1863 | 0.0006 | 0.0000 | 0.0046 | 0.0003 | 0.0191 | 0.0016 | 0.0469 | 0.0087 | 0.0879 | 0.0304 | 0.1387 | 0.0535 | 0.1808 | 0.0957 | 0.2333 | 0.2328 | 0.2882 | 0.5769 | 0.0957 | 0.1536 | 0.1428 | 0.1826 | 0.1400 | 0.1273 | 0.1328 | 0.0834 | 0.1079 | 0.0869 | 0.1063 | 0.0860 | 0.0847 | 0.0808 | 0.0841 | 0.0939 | 0.1057 | 0.1054 | 0.0056 | 0.0360 | 0.0685 | 0.1045 | 0.1391 | 0.1650 | 0.1550 | 0.1468 | 0.1796 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 706 | 476 | 728 | 1022 | 96.1 | 32.97 | 217.29 | 252.33 | 64 | 70 | 76 | 81 | 87 | 93 | 104 | 119 | 143 | 0.2652 | 271 | 0.410 | 145.45 | 41.40 | 1 | 0.7843 | 571 | 0.0039 | 22.73 | 5.781 | 0.2516 | 10321.1 | 1250000 | 169000000 | 25300000000 | 0.4351 | 0.2119 | 0.0000 | 0.0000 | 0.0173 | 0.0066 | 0.0202 | 0.0099 | 0.0980 | 0.0066 | 0.2161 | 0.0724 | 0.2017 | 0.0938 | 0.2017 | 0.0674 | 0.1441 | 0.1628 | 0.1009 | 0.5806 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0296 | 0.0029 | 0.1006 | 0.0471 | 0.1381 | 0.0799 | 0.1282 | 0.0428 | 0.1440 | 0.1084 | 0.4576 | 0.7190 | 0.0000 | 0.0215 | 0.0000 | 0.0000 | 0.0375 | 0.0000 | 0.0625 | 0.0753 | 0.1438 | 0.1183 | 0.1563 | 0.1720 | 0.1063 | 0.2151 | 0.1438 | 0.1398 | 0.3500 | 0.2581 | 0.0037 | 0.0000 | 0.0112 | 0.0669 | 0.1227 | 0.1450 | 0.0558 | 0.1004 | 0.4944 | 18 | 22 | 28 | 45 | 88 | 168 | 297 | 431 | 602 | 0.0497 | 49.53 | 4.975 | 0.4355 | 110822.0 | 73200000 | 55400000000 | 45800000000000 | 0.5813 | 0.0827 | 0.1029 | 0.0000 | 0.2500 | 0.0581 | 0.3971 | 0.1806 | 0.1324 | 0.2581 | 0.0735 | 0.2387 | 0.0147 | 0.1355 | 0.0294 | 0.0774 | 0.0000 | 0.0387 | 0.0000 | 0.0129 | 0.0000 | 0.0000 | 0.0050 | 0.0022 | 0.0074 | 0.0022 | 0.0074 | 0.0285 | 0.0695 | 0.0724 | 0.1390 | 0.1162 | 0.0893 | 0.0943 | 0.1216 | 0.1250 | 0.5608 | 0.5592 | 0.0000 | 0.0000 | 0.0000 | 0.0033 | 0.0090 | 0.0000 | 0.0090 | 0.0233 | 0.0746 | 0.0731 | 0.1731 | 0.1728 | 0.0836 | 0.1163 | 0.1313 | 0.1262 | 0.5194 | 0.4851 | 0.0000 | 0.0000 | 0.0028 | 0.0110 | 0.0579 | 0.1818 | 0.0661 | 0.1350 | 0.5455 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 146 | 51 | 354 | 2232 | 83.5 | 10.81 | 232.77 | 142.92 | 70 | 73 | 77 | 80 | 83 | 86 | 89 | 94 | 99 | 0.1223 | 273 | 1.033 | 88.84 | 22.85 | 0 | 0.5791 | 205 | 0.0101 | 9.66 | 4.753 | 0.3349 | 7088.7 | 611712 | 53600000 | 4780000000 | 0.4194 | 0.1966 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0130 | 0.0028 | 0.0357 | 0.0085 | 0.0779 | 0.0397 | 0.1331 | 0.1473 | 0.1331 | 0.0368 | 0.2110 | 0.0822 | 0.3929 | 0.6827 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0030 | 0.0028 | 0.0178 | 0.0056 | 0.0562 | 0.0424 | 0.1124 | 0.1441 | 0.0621 | 0.0339 | 0.1213 | 0.0763 | 0.6243 | 0.6949 | 0.0000 | 1.0000 | 0.1000 | 0.0000 | 0.3667 | 0.0000 | 0.1000 | 0.0000 | 0.1667 | 0.0000 | 0.1333 | 0.0000 | 0.0667 | 0.0000 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0430 | 0.0699 | 0.1505 | 0.1720 | 0.1290 | 0.1559 | 0.2688 | 68 | 106 | 142 | 176 | 210 | 248 | 292 | 342 | 423 | 0.0013 | 85.74 | 6.901 | 0.1836 | 74597.8 | 29500000 | 13700000000 | 7190000000000 | 0.4379 | 0.1909 | 0.0169 | 0.0028 | 0.0639 | 0.0075 | 0.1899 | 0.0197 | 0.2199 | 0.0563 | 0.1748 | 0.1315 | 0.1485 | 0.1840 | 0.0846 | 0.1897 | 0.0639 | 0.1615 | 0.0376 | 0.2469 | 0.0008 | 0.0013 | 0.0016 | 0.0019 | 0.0055 | 0.0044 | 0.0181 | 0.0120 | 0.0604 | 0.0405 | 0.1319 | 0.0790 | 0.0981 | 0.0765 | 0.1389 | 0.0967 | 0.5447 | 0.6877 | 0.0013 | 0.0039 | 0.0054 | 0.0135 | 0.0148 | 0.0271 | 0.0620 | 0.0832 | 0.1334 | 0.1605 | 0.1536 | 0.1741 | 0.1361 | 0.1586 | 0.1860 | 0.1470 | 0.3073 | 0.2321 | 0.0000 | 0.0020 | 0.0121 | 0.0302 | 0.1099 | 0.1532 | 0.1149 | 0.1734 | 0.4042 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 872 | 892 | 3689 | 8762 | 488.5 | 108.21 | 84.63 | 135.98 | 344 | 390 | 427 | 458 | 489 | 518 | 545 | 576 | 623 | 0.0781 | 684 | 1.133 | 118.56 | 47.04 | 1 | 0.0848 | 313 | 0.0006 | 83.19 | 7.600 | 0.1213 | 250362.0 | 134000000 | 74800000000 | 43400000000000 | 0.4340 | 0.2055 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0153 | 0.0026 | 0.0610 | 0.0249 | 0.1194 | 0.0435 | 0.1225 | 0.0384 | 0.1500 | 0.0501 | 0.5305 | 0.8402 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0075 | 0.0017 | 0.0282 | 0.0215 | 0.0411 | 0.0345 | 0.0380 | 0.0246 | 0.0598 | 0.0328 | 0.8247 | 0.8846 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0231 | 0.0000 | 0.0738 | 0.0000 | 0.1323 | 0.0000 | 0.1877 | 0.0000 | 0.1092 | 0.0000 | 0.1154 | 0.0000 | 0.3569 | 0.0000 | 0.0000 | 0.0011 | 0.0032 | 0.0151 | 0.0572 | 0.1068 | 0.0766 | 0.1176 | 0.6224 | 14 | 16 | 19 | 24 | 34 | 51 | 71 | 100 | 208 | 0.0576 | 11.33 | 4.133 | 0.6484 | 25648.9 | 14400000 | 10400000000 | 8570000000000 | 0.5629 | 0.1030 | 0.0175 | 0.0040 | 0.0903 | 0.0070 | 0.1233 | 0.0663 | 0.1155 | 0.0713 | 0.1291 | 0.1216 | 0.1107 | 0.1266 | 0.1097 | 0.1077 | 0.1175 | 0.1171 | 0.1864 | 0.3784 | 0.0014 | 0.0017 | 0.0025 | 0.0028 | 0.0076 | 0.0083 | 0.0245 | 0.0185 | 0.0736 | 0.0578 | 0.0848 | 0.0797 | 0.0704 | 0.0606 | 0.1050 | 0.0857 | 0.6301 | 0.6850 | 0.0011 | 0.0007 | 0.0011 | 0.0027 | 0.0080 | 0.0066 | 0.0218 | 0.0199 | 0.0856 | 0.0922 | 0.1287 | 0.1293 | 0.0666 | 0.0663 | 0.1034 | 0.1015 | 0.5836 | 0.5809 | 0.0042 | 0.0056 | 0.0075 | 0.0258 | 0.0714 | 0.1104 | 0.0770 | 0.0968 | 0.6012 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 193 | 840 | 364 | 9991 | 79.4 | 12.33 | 120.69 | 125.11 | 64 | 69 | 71 | 74 | 78 | 82 | 86 | 91 | 97 | 0.0656 | 655 | 0.892 | 100.23 | 30.02 | 0 | 0.7033 | 256 | 0.0097 | 8.20 | 4.818 | 0.3329 | 6458.0 | 537560 | 45800000 | 3980000000 | 0.4026 | 0.2222 | 0.0000 | 0.0000 | 0.0248 | 0.0028 | 0.0106 | 0.0055 | 0.0496 | 0.0138 | 0.1028 | 0.0608 | 0.1950 | 0.1326 | 0.1915 | 0.0856 | 0.2340 | 0.1105 | 0.1915 | 0.5884 | 0.0000 | 0.0000 | 0.0210 | 0.0027 | 0.0060 | 0.0055 | 0.0330 | 0.0137 | 0.0571 | 0.0604 | 0.1171 | 0.1319 | 0.0781 | 0.0742 | 0.1171 | 0.0934 | 0.5706 | 0.6181 | 0.0196 | 0.0000 | 0.0980 | 1.0000 | 0.0392 | 0.0000 | 0.2549 | 0.0000 | 0.1765 | 0.0000 | 0.2157 | 0.0000 | 0.0980 | 0.0000 | 0.0980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0229 | 0.0571 | 0.0400 | 0.0971 | 0.1371 | 0.1371 | 0.1771 | 0.3314 | 24 | 37 | 47 | 57 | 70 | 90 | 126 | 190 | 293 | 0.0082 | 25.67 | 5.863 | 0.4219 | 30214.6 | 11500000 | 5470000000 | 2990000000000 | 0.6670 | 0.0790 | 0.0168 | 0.0063 | 0.0841 | 0.0145 | 0.1639 | 0.0396 | 0.1869 | 0.0903 | 0.1913 | 0.1538 | 0.1665 | 0.1778 | 0.0939 | 0.1436 | 0.0709 | 0.1429 | 0.0257 | 0.2312 | 0.0013 | 0.0029 | 0.0042 | 0.0050 | 0.0088 | 0.0091 | 0.0255 | 0.0213 | 0.0682 | 0.0615 | 0.1043 | 0.0886 | 0.0823 | 0.0797 | 0.1139 | 0.1042 | 0.5915 | 0.6276 | 0.0008 | 0.0009 | 0.0049 | 0.0070 | 0.0167 | 0.0127 | 0.0318 | 0.0417 | 0.0864 | 0.0961 | 0.1262 | 0.1298 | 0.0936 | 0.1039 | 0.1259 | 0.1373 | 0.5136 | 0.4706 | 0.0016 | 0.0055 | 0.0109 | 0.0257 | 0.0792 | 0.1136 | 0.0911 | 0.1171 | 0.5553 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 765 | 448 | 1036 | 4704 | 600.2 | 210.48 | 6.20 | 1.84 | 332 | 391 | 444 | 509 | 577 | 659 | 743 | 818 | 904 | 0.0897 | 422 | 1.225 | 53.31 | 21.95 | 1 | 0.1332 | 138 | 0.0016 | 24.08 | 6.554 | 0.2404 | 404516.0 | 298000000 | 234000000000 | 192000000000000 | 0.3419 | 0.2894 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0031 | 0.0043 | 0.1242 | 0.0558 | 0.2329 | 0.1016 | 0.1304 | 0.0629 | 0.1739 | 0.0801 | 0.3354 | 0.6938 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0392 | 0.0339 | 0.0633 | 0.0532 | 0.0271 | 0.0271 | 0.0542 | 0.0407 | 0.8163 | 0.8439 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0324 | 0.0585 | 0.0649 | 0.0848 | 0.1135 | 0.0409 | 0.0757 | 0.0673 | 0.0811 | 0.7427 | 0.6324 | 0.0000 | 0.0000 | 0.0021 | 0.0062 | 0.0374 | 0.0811 | 0.0395 | 0.0457 | 0.7879 | 4 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 8 | 0.0274 | 6.20 | 3.980 | 0.3875 | 41.8 | 302.145 | 2320.55 | 18932.6 | 0.4537 | 0.1856 | 0.0023 | 0.0005 | 0.0113 | 0.0013 | 0.0441 | 0.0090 | 0.1027 | 0.0249 | 0.1782 | 0.0542 | 0.2398 | 0.1111 | 0.2262 | 0.2325 | 0.1613 | 0.3262 | 0.0341 | 0.2402 | 0.0000 | 0.0000 | 0.0017 | 0.0005 | 0.0047 | 0.0016 | 0.0231 | 0.0099 | 0.0540 | 0.0309 | 0.1005 | 0.0574 | 0.1816 | 0.1030 | 0.3028 | 0.2870 | 0.3314 | 0.5097 | 0.1740 | 0.3416 | 0.2290 | 0.2805 | 0.1980 | 0.1584 | 0.1530 | 0.1041 | 0.1140 | 0.0679 | 0.0770 | 0.0181 | 0.0260 | 0.0158 | 0.0230 | 0.0090 | 0.0060 | 0.0045 | 0.0029 | 0.0141 | 0.0417 | 0.0959 | 0.1617 | 0.2172 | 0.2159 | 0.1543 | 0.0962 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 373 | 297 | 8100 | 26881 | 413.8 | 80.21 | 134.66 | 112.18 | 311 | 343 | 368 | 389 | 410 | 432 | 457 | 483 | 520 | 0.0428 | 1150 | 1.063 | 121.84 | 35.38 | 1 | 0.0363 | 294 | 0.0012 | 29.87 | 6.930 | 0.2112 | 177657.0 | 78900000 | 36200000000 | 17100000000000 | 0.4441 | 0.2061 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0031 | 0.0001 | 0.0127 | 0.0006 | 0.0529 | 0.0119 | 0.1206 | 0.0278 | 0.1395 | 0.0227 | 0.1558 | 0.0414 | 0.5151 | 0.8954 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0038 | 0.0005 | 0.0215 | 0.0096 | 0.0486 | 0.0211 | 0.0558 | 0.0122 | 0.0700 | 0.0216 | 0.7987 | 0.9350 | 0.0038 | 0.0471 | 0.0045 | 0.0059 | 0.0257 | 0.0941 | 0.0863 | 0.1588 | 0.1529 | 0.1412 | 0.2044 | 0.2118 | 0.1317 | 0.0647 | 0.1363 | 0.0706 | 0.2544 | 0.2059 | 0.0005 | 0.0013 | 0.0066 | 0.0247 | 0.0683 | 0.1268 | 0.1056 | 0.1298 | 0.5363 | 27 | 46 | 66 | 85 | 107 | 130 | 159 | 200 | 272 | 0.0091 | 10.68 | 5.490 | 0.4380 | 30717.4 | 10300000 | 4530000000 | 2410000000000 | 0.4651 | 0.1879 | 0.0107 | 0.0010 | 0.0569 | 0.0033 | 0.1502 | 0.0207 | 0.1620 | 0.0586 | 0.1808 | 0.1345 | 0.1705 | 0.1748 | 0.1171 | 0.1516 | 0.0871 | 0.1645 | 0.0646 | 0.2909 | 0.0008 | 0.0005 | 0.0020 | 0.0009 | 0.0061 | 0.0038 | 0.0179 | 0.0117 | 0.0589 | 0.0446 | 0.1034 | 0.0774 | 0.0837 | 0.0680 | 0.1176 | 0.1006 | 0.6097 | 0.6925 | 0.0016 | 0.0022 | 0.0055 | 0.0050 | 0.0095 | 0.0162 | 0.0356 | 0.0429 | 0.0832 | 0.1003 | 0.1356 | 0.1457 | 0.1111 | 0.1195 | 0.1349 | 0.1425 | 0.4830 | 0.4257 | 0.0007 | 0.0045 | 0.0076 | 0.0250 | 0.0755 | 0.1170 | 0.0983 | 0.1280 | 0.5435 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 560 | 270 | 5568 | 18268 | 433.5 | 92.93 | 137.20 | 136.94 | 324 | 352 | 376 | 397 | 422 | 446 | 477 | 510 | 564 | 0.0541 | 989 | 1.182 | 95.60 | 36.50 | 1 | 0.0449 | 250 | 0.0012 | 33.93 | 7.010 | 0.1946 | 196527.0 | 93100000 | 46100000000 | 23700000000000 | 0.4332 | 0.2136 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0020 | 0.0002 | 0.0140 | 0.0011 | 0.0717 | 0.0192 | 0.1259 | 0.0400 | 0.1320 | 0.0390 | 0.1664 | 0.0581 | 0.4877 | 0.8422 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0064 | 0.0000 | 0.0304 | 0.0128 | 0.0556 | 0.0229 | 0.0530 | 0.0152 | 0.0754 | 0.0265 | 0.7781 | 0.9225 | 0.0031 | 0.0070 | 0.0071 | 0.0245 | 0.0224 | 0.0280 | 0.0671 | 0.1294 | 0.1180 | 0.1993 | 0.1699 | 0.2133 | 0.1282 | 0.1084 | 0.1506 | 0.1434 | 0.3337 | 0.1469 | 0.0020 | 0.0016 | 0.0052 | 0.0290 | 0.0708 | 0.1225 | 0.0982 | 0.1301 | 0.5406 | 20 | 35 | 55 | 76 | 97 | 124 | 159 | 209 | 290 | 0.0125 | 11.31 | 5.396 | 0.4946 | 37572.9 | 16400000 | 9620000000 | 6730000000000 | 0.5560 | 0.1152 | 0.0139 | 0.0011 | 0.0448 | 0.0071 | 0.1227 | 0.0245 | 0.1370 | 0.0568 | 0.1652 | 0.1234 | 0.1675 | 0.1608 | 0.1217 | 0.1315 | 0.1118 | 0.1516 | 0.1154 | 0.3433 | 0.0013 | 0.0001 | 0.0016 | 0.0026 | 0.0052 | 0.0039 | 0.0169 | 0.0131 | 0.0498 | 0.0475 | 0.0829 | 0.0732 | 0.0663 | 0.0599 | 0.0861 | 0.0802 | 0.6900 | 0.7194 | 0.0015 | 0.0007 | 0.0029 | 0.0034 | 0.0061 | 0.0079 | 0.0209 | 0.0274 | 0.0672 | 0.0758 | 0.1087 | 0.1185 | 0.0846 | 0.0902 | 0.1045 | 0.1152 | 0.6036 | 0.5609 | 0.0021 | 0.0021 | 0.0044 | 0.0190 | 0.0539 | 0.0970 | 0.0768 | 0.0992 | 0.6453 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 177 | 313 | 5638 | 13933 | 398.6 | 102.35 | 102.66 | 164.28 | 278 | 312 | 338 | 363 | 391 | 418 | 444 | 477 | 530 | 0.0646 | 900 | 1.105 | 128.16 | 40.36 | 1 | 0.0566 | 319 | 0.0011 | 32.90 | 7.036 | 0.2099 | 169382.0 | 76400000 | 36500000000 | 18500000000000 | 0.3917 | 0.2443 | 0.0000 | 0.0002 | 0.0018 | 0.0000 | 0.0052 | 0.0006 | 0.0231 | 0.0041 | 0.0686 | 0.0246 | 0.1196 | 0.0553 | 0.1310 | 0.0452 | 0.1734 | 0.0712 | 0.4774 | 0.7988 | 0.0000 | 0.0002 | 0.0007 | 0.0000 | 0.0025 | 0.0004 | 0.0080 | 0.0026 | 0.0243 | 0.0159 | 0.0491 | 0.0316 | 0.0505 | 0.0232 | 0.0757 | 0.0338 | 0.7892 | 0.8923 | 0.0054 | 0.0078 | 0.0045 | 0.0207 | 0.0118 | 0.0181 | 0.0570 | 0.0622 | 0.1230 | 0.1425 | 0.1203 | 0.2409 | 0.1401 | 0.1295 | 0.1528 | 0.1529 | 0.3852 | 0.2254 | 0.0011 | 0.0011 | 0.0023 | 0.0196 | 0.0495 | 0.1072 | 0.0966 | 0.1076 | 0.6149 | 10 | 13 | 19 | 31 | 50 | 75 | 104 | 145 | 221 | 0.0586 | 9.85 | 4.528 | 0.5850 | 37525.9 | 28000000 | 28100000000 | 32100000000000 | 0.6066 | 0.1047 | 0.0130 | 0.0014 | 0.0691 | 0.0060 | 0.1943 | 0.0246 | 0.2038 | 0.0773 | 0.1991 | 0.1586 | 0.1471 | 0.2025 | 0.0939 | 0.1627 | 0.0585 | 0.1518 | 0.0213 | 0.2151 | 0.0004 | 0.0002 | 0.0023 | 0.0006 | 0.0041 | 0.0022 | 0.0209 | 0.0180 | 0.0638 | 0.0512 | 0.0976 | 0.0888 | 0.0749 | 0.0667 | 0.1049 | 0.0915 | 0.6311 | 0.6808 | 0.0012 | 0.0036 | 0.0023 | 0.0047 | 0.0092 | 0.0118 | 0.0286 | 0.0383 | 0.0754 | 0.0777 | 0.1265 | 0.1310 | 0.0826 | 0.0917 | 0.1129 | 0.1167 | 0.5614 | 0.5245 | 0.0014 | 0.0033 | 0.0064 | 0.0226 | 0.0683 | 0.1045 | 0.0824 | 0.1106 | 0.6005 | |
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 729 | 312 | 7306 | 11974 | 613.3 | 129.28 | 138.56 | 260.97 | 460 | 513 | 546 | 576 | 604 | 631 | 663 | 705 | 779 | 0.0833 | 997 | 1.173 | 110.11 | 34.67 | 1 | 0.0356 | 260 | 0.0006 | 91.47 | 7.747 | 0.1387 | 392795.0 | 263000000 | 183000000000 | 133000000000000 | 0.4412 | 0.2054 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0004 | 0.0084 | 0.0022 | 0.0416 | 0.0166 | 0.0910 | 0.0363 | 0.1054 | 0.0298 | 0.1371 | 0.0406 | 0.6140 | 0.8741 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0004 | 0.0024 | 0.0010 | 0.0180 | 0.0122 | 0.0418 | 0.0199 | 0.0422 | 0.0119 | 0.0634 | 0.0208 | 0.8310 | 0.9338 | 0.0046 | 0.0000 | 0.0092 | 0.0029 | 0.0295 | 0.0146 | 0.0867 | 0.1108 | 0.0941 | 0.1837 | 0.1614 | 0.2157 | 0.1144 | 0.1224 | 0.1153 | 0.1079 | 0.3847 | 0.2420 | 0.0015 | 0.0056 | 0.0082 | 0.0316 | 0.0647 | 0.1109 | 0.0989 | 0.1229 | 0.5559 | 6 | 8 | 9 | 13 | 22 | 47 | 98 | 198 | 434 | 0.0993 | 31.78 | 4.313 | 0.5808 | 87298.6 | 89300000 | 118000000000 | 185000000000000 | 0.4711 | 0.1719 | 0.0442 | 0.0014 | 0.1509 | 0.0196 | 0.2302 | 0.0825 | 0.2088 | 0.0965 | 0.1814 | 0.1972 | 0.0838 | 0.1930 | 0.0427 | 0.1343 | 0.0381 | 0.1273 | 0.0198 | 0.1483 | 0.0003 | 0.0005 | 0.0009 | 0.0005 | 0.0009 | 0.0018 | 0.0089 | 0.0096 | 0.0546 | 0.0480 | 0.1005 | 0.0828 | 0.0650 | 0.0568 | 0.0942 | 0.0835 | 0.6747 | 0.7164 | 0.0004 | 0.0004 | 0.0004 | 0.0012 | 0.0022 | 0.0008 | 0.0115 | 0.0144 | 0.0749 | 0.0804 | 0.1197 | 0.1267 | 0.0782 | 0.0776 | 0.1019 | 0.1110 | 0.6108 | 0.5875 | 0.0000 | 0.0003 | 0.0013 | 0.0127 | 0.0586 | 0.1195 | 0.0696 | 0.0917 | 0.6463 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 287 | 523 | 301 | 5124 | 89.9 | 7.90 | 7.40 | 2.14 | 79 | 82 | 86 | 88 | 90 | 93 | 95 | 97 | 100 | 0.0720 | 369 | 0.946 | 37.36 | 10.77 | 0 | 0.3223 | 97 | 0.1482 | 0.45 | 2.153 | 0.7860 | 8141.3 | 742840 | 68300000 | 6310000000 | 0.3690 | 0.2667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0066 | 0.0567 | 0.0532 | 0.0767 | 0.0831 | 0.0467 | 0.0432 | 0.0567 | 0.0565 | 0.7567 | 0.7575 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0066 | 0.0567 | 0.0532 | 0.0767 | 0.0831 | 0.0467 | 0.0432 | 0.0567 | 0.0565 | 0.7567 | 0.7575 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0120 | 0.0120 | 0.0542 | 0.0482 | 0.0783 | 0.1205 | 0.1084 | 0.5663 | 5 | 6 | 6 | 7 | 7 | 8 | 8 | 9 | 10 | 0.1708 | 0.51 | 1.021 | 0.4581 | 59.3 | 508.117 | 4604.6 | 43888.8 | 0.4666 | 0.2005 | 0.0058 | 0.0003 | 0.0341 | 0.0016 | 0.0942 | 0.0123 | 0.1790 | 0.0503 | 0.2344 | 0.1168 | 0.2308 | 0.1953 | 0.1477 | 0.2794 | 0.0651 | 0.2535 | 0.0090 | 0.0906 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0070 | 0.0015 | 0.0224 | 0.0088 | 0.0627 | 0.0354 | 0.1193 | 0.0626 | 0.1833 | 0.1375 | 0.3291 | 0.3390 | 0.2756 | 0.4152 | 0.0900 | 0.2589 | 0.1985 | 0.3018 | 0.2363 | 0.2417 | 0.2038 | 0.1227 | 0.1456 | 0.0577 | 0.0887 | 0.0135 | 0.0278 | 0.0025 | 0.0093 | 0.0012 | 0.0000 | 0.0000 | 0.0003 | 0.0097 | 0.0436 | 0.0951 | 0.1730 | 0.2360 | 0.2304 | 0.1642 | 0.0477 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1017 | 174 | 1248 | 1851 | 214.5 | 155.04 | 45.32 | 44.12 | 105 | 122 | 135 | 145 | 159 | 175 | 196 | 246 | 453 | 0.2150 | 398 | 0.886 | 138.05 | 45.25 | 2 | 0.3045 | 380 | 0.0030 | 54.71 | 6.166 | 0.2695 | 70037.8 | 33300000 | 19600000000 | 12700000000000 | 0.3408 | 0.2642 | 0.0000 | 0.0014 | 0.0105 | 0.0000 | 0.0592 | 0.0027 | 0.0941 | 0.0095 | 0.2056 | 0.0846 | 0.1638 | 0.1419 | 0.0906 | 0.1132 | 0.1289 | 0.1050 | 0.2474 | 0.5416 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0076 | 0.0011 | 0.0191 | 0.0085 | 0.0841 | 0.0512 | 0.1071 | 0.0800 | 0.0650 | 0.0597 | 0.1071 | 0.0778 | 0.6099 | 0.7207 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0169 | 0.0098 | 0.0805 | 0.1073 | 0.1059 | 0.1024 | 0.0551 | 0.0488 | 0.0975 | 0.1024 | 0.6441 | 0.6293 | 0.0032 | 0.0097 | 0.0097 | 0.0130 | 0.0909 | 0.0942 | 0.0390 | 0.1039 | 0.6364 | 20 | 22 | 25 | 27 | 30 | 34 | 39 | 51 | 87 | 0.1634 | 0.96 | 2.528 | 0.7872 | 4000.0 | 623754 | 127000000 | 29000000000 | 0.5672 | 0.0956 | 0.0344 | 0.0145 | 0.0875 | 0.0190 | 0.1375 | 0.0335 | 0.1313 | 0.0760 | 0.1906 | 0.1229 | 0.2000 | 0.1508 | 0.1156 | 0.1620 | 0.0688 | 0.1721 | 0.0344 | 0.2492 | 0.0106 | 0.0111 | 0.0257 | 0.0146 | 0.0287 | 0.0231 | 0.0332 | 0.0446 | 0.0861 | 0.0788 | 0.1344 | 0.0925 | 0.1239 | 0.1071 | 0.1360 | 0.1500 | 0.4215 | 0.4781 | 0.0029 | 0.0037 | 0.0088 | 0.0368 | 0.0205 | 0.0404 | 0.0526 | 0.0772 | 0.1404 | 0.0919 | 0.1725 | 0.1287 | 0.1023 | 0.1213 | 0.1287 | 0.1103 | 0.3713 | 0.3897 | 0.0022 | 0.0155 | 0.0310 | 0.0376 | 0.1062 | 0.1372 | 0.1261 | 0.1482 | 0.3960 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 465 | 643 | 8720 | 12380 | 327.7 | 56.71 | 178.47 | 263.33 | 253 | 288 | 306 | 320 | 333 | 346 | 358 | 371 | 394 | 0.0826 | 1023 | 1.053 | 189.34 | 55.01 | 1 | 0.0515 | 449 | 0.0016 | 19.71 | 6.739 | 0.2552 | 110617.0 | 38300000 | 13500000000 | 4860000000000 | 0.4132 | 0.2316 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0010 | 0.0001 | 0.0059 | 0.0010 | 0.0246 | 0.0101 | 0.0541 | 0.0199 | 0.0557 | 0.0130 | 0.0950 | 0.0226 | 0.7636 | 0.9332 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0001 | 0.0030 | 0.0009 | 0.0126 | 0.0096 | 0.0228 | 0.0178 | 0.0228 | 0.0096 | 0.0370 | 0.0162 | 0.9017 | 0.9456 | 0.0114 | 0.0000 | 0.0227 | 0.0000 | 0.0272 | 0.0000 | 0.0681 | 0.0000 | 0.0988 | 0.0000 | 0.1703 | 0.0000 | 0.1067 | 0.0000 | 0.1226 | 0.0000 | 0.3723 | 0.0000 | 0.0008 | 0.0019 | 0.0071 | 0.0173 | 0.0483 | 0.0854 | 0.0861 | 0.1201 | 0.6330 | 18 | 25 | 36 | 52 | 72 | 98 | 148 | 262 | 503 | 0.0250 | 35.86 | 5.284 | 0.5431 | 101188.0 | 92200000 | 104000000000 | 133000000000000 | 0.5504 | 0.1103 | 0.0118 | 0.0028 | 0.0634 | 0.0052 | 0.1160 | 0.0282 | 0.1461 | 0.0612 | 0.1912 | 0.1266 | 0.1751 | 0.1507 | 0.1224 | 0.1351 | 0.0988 | 0.1573 | 0.0752 | 0.3329 | 0.0005 | 0.0002 | 0.0003 | 0.0011 | 0.0024 | 0.0023 | 0.0079 | 0.0094 | 0.0482 | 0.0428 | 0.0854 | 0.0656 | 0.0514 | 0.0563 | 0.0801 | 0.0808 | 0.7238 | 0.7415 | 0.0000 | 0.0000 | 0.0021 | 0.0008 | 0.0042 | 0.0035 | 0.0101 | 0.0097 | 0.0538 | 0.0635 | 0.0894 | 0.0884 | 0.0594 | 0.0666 | 0.0876 | 0.0970 | 0.6934 | 0.6706 | 0.0000 | 0.0003 | 0.0031 | 0.0089 | 0.0520 | 0.0851 | 0.0560 | 0.0875 | 0.7072 |