High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 692 185 image if available 19415 44441 368.7 56.02 244.04 276.54 299 324 341 357 370 384 398 414 438 0.0403 1792 0.714 124.33 24.70 1 0.0157 305 0.0014 22.18 6.923 0.2357 139081.0
53500000
21000000000
8390000000000
0.4311 0.2269 0.0001 0.0000 0.0008 0.0001 0.0028 0.0001 0.0066 0.0002 0.0259 0.0087 0.0530 0.0182 0.0576 0.0109 0.0865 0.0176 0.7667 0.9443 0.0001 0.0000 0.0004 0.0001 0.0011 0.0001 0.0033 0.0002 0.0141 0.0084 0.0282 0.0172 0.0273 0.0090 0.0375 0.0134 0.8880 0.9517 0.0119 0.0000 0.0209 0.0000 0.0346 0.0000 0.0930 0.0000 0.1169 0.0000 0.1574 0.0000 0.1199 0.0000 0.1306 0.0000 0.3148 0.0000 0.0012 0.0035 0.0100 0.0254 0.0509 0.0848 0.0988 0.1192 0.6061 17 22 30 54 118 220 341 473 647 0.0281 44.65 6.124 0.4266 136024.0
100000000
87800000000
88300000000000
0.4534 0.1804 0.0700 0.0020 0.2411 0.0134 0.3304 0.1499 0.1469 0.1951 0.0898 0.2149 0.0610 0.1886 0.0354 0.0976 0.0173 0.0724 0.0080 0.0662 0.0003 0.0002 0.0010 0.0004 0.0018 0.0013 0.0092 0.0076 0.0506 0.0416 0.1014 0.0881 0.0667 0.0543 0.0944 0.0803 0.6746 0.7262 0.0007 0.0004 0.0014 0.0017 0.0031 0.0043 0.0147 0.0194 0.0670 0.0789 0.1259 0.1392 0.0883 0.0943 0.1136 0.1275 0.5852 0.5343 0.0001 0.0007 0.0030 0.0105 0.0587 0.1131 0.0775 0.1049 0.6315
SK-BR-3 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 406 653 image if available 9716 23603 431.9 88.96 349.44 405.84 326 380 406 425 442 459 475 495 525 0.0445 1051 1.155 114.98 44.01 1 0.0310 301 0.0009 57.02 7.395 0.1756 194415.0
90200000
42900000000
20900000000000
0.4256 0.2144 0.0000 0.0000 0.0001 0.0000 0.0024 0.0002 0.0073 0.0009 0.0306 0.0101 0.0644 0.0220 0.0617 0.0172 0.1018 0.0289 0.7315 0.9207 0.0000 0.0000 0.0000 0.0000 0.0001 0.0000 0.0014 0.0003 0.0115 0.0083 0.0248 0.0165 0.0200 0.0081 0.0331 0.0149 0.9091 0.9519 0.0122 0.0252 0.0157 0.0692 0.0332 0.0503 0.0752 0.1195 0.1461 0.2201 0.1785 0.1698 0.1400 0.0943 0.1417 0.1321 0.2572 0.1195 0.0002 0.0018 0.0031 0.0201 0.0458 0.0885 0.0915 0.1196 0.6294 11 15 26 74 177 311 477 692 979 0.0386 101.07 6.457 0.3962 286810.0
301000000
364000000000
491000000000000
0.5288 0.1335 0.0292 0.0023 0.1390 0.0075 0.2010 0.0674 0.1542 0.1168 0.1584 0.1632 0.1246 0.1791 0.0806 0.1344 0.0556 0.1290 0.0574 0.2002 0.0001 0.0001 0.0006 0.0003 0.0019 0.0007 0.0085 0.0046 0.0443 0.0358 0.0839 0.0706 0.0599 0.0519 0.0888 0.0796 0.7120 0.7564 0.0001 0.0003 0.0008 0.0014 0.0045 0.0043 0.0123 0.0170 0.0555 0.0621 0.1009 0.1122 0.0725 0.0814 0.1086 0.1185 0.6449 0.6027 0.0005 0.0014 0.0034 0.0121 0.0467 0.0905 0.0701 0.0917 0.6837
MCF7
0
DRAQ5 1 TMRE 2 2 2 1 241 848 image if available 10173 33400 558.7 106.36 141.20 210.07 440 469 494 517 539 564 595 638 721 0.0340 1136 1.181 125.88 48.08 1 0.0321 327 0.0010 33.71 7.169 0.1994 323447.0
194000000
121000000000
78500000000000
0.3999 0.2475 0.0004 0.0002 0.0009 0.0001 0.0027 0.0002 0.0123 0.0021 0.0344 0.0148 0.0701 0.0282 0.0822 0.0219 0.1201 0.0283 0.6769 0.9042 0.0002 0.0000 0.0004 0.0000 0.0012 0.0000 0.0077 0.0002 0.0193 0.0092 0.0401 0.0151 0.0464 0.0088 0.0651 0.0146 0.8195 0.9521 0.0060 0.0020 0.0079 0.0101 0.0113 0.0061 0.0344 0.0869 0.0656 0.1212 0.0947 0.2222 0.0742 0.1253 0.0947 0.1616 0.6113 0.2646 0.0019 0.0063 0.0137 0.0288 0.0574 0.1020 0.0876 0.1004 0.6019 7 9 12 16 31 71 144 264 446 0.0759 52.63 5.308 0.4892 64064.9
41000000
31800000000
28400000000000
0.3985 0.2299 0.1332 0.0028 0.3108 0.0481 0.2982 0.2452 0.1039 0.2139 0.0716 0.1845 0.0484 0.1328 0.0222 0.0737 0.0081 0.0576 0.0035 0.0413 0.0002 0.0002 0.0008 0.0002 0.0013 0.0007 0.0107 0.0085 0.0677 0.0583 0.1067 0.0940 0.0684 0.0620 0.1038 0.0989 0.6404 0.6771 0.0001 0.0001 0.0004 0.0005 0.0018 0.0038 0.0161 0.0195 0.0838 0.0907 0.1222 0.1354 0.0813 0.0869 0.1259 0.1305 0.5681 0.5326 0.0003 0.0006 0.0013 0.0134 0.0759 0.1150 0.0717 0.1123 0.6096
MCF7
0
DRAQ5 1 TMRE 2 2 2 1 621 832 image if available 10045 16653 624.4 136.14 146.38 247.89 478 513 544 571 595 625 662 712 830 0.0671 1118 1.208 132.46 56.89 1 0.0353 355 0.0011 29.04 7.171 0.2381 408412.0
281000000
204000000000
157000000000000
0.4086 0.2413 0.0006 0.0000 0.0012 0.0000 0.0023 0.0007 0.0125 0.0016 0.0328 0.0154 0.0584 0.0291 0.0670 0.0221 0.0956 0.0345 0.7297 0.8966 0.0005 0.0000 0.0006 0.0000 0.0014 0.0000 0.0072 0.0002 0.0161 0.0088 0.0293 0.0152 0.0349 0.0084 0.0505 0.0148 0.8595 0.9526 0.0006 0.0029 0.0069 0.0073 0.0075 0.0190 0.0162 0.0321 0.0643 0.1226 0.0899 0.1431 0.0762 0.1080 0.1043 0.1328 0.6340 0.4321 0.0025 0.0025 0.0069 0.0195 0.0468 0.0683 0.0678 0.0849 0.7009 4 5 6 8 10 19 116 297 537 0.1488 72.06 4.406 0.5290 82870.7
61800000
54900000000
56100000000000
0.4135 0.2138 0.0751 0.0057 0.2521 0.0378 0.2654 0.1946 0.1669 0.1626 0.1135 0.1847 0.0785 0.1782 0.0234 0.1043 0.0200 0.0796 0.0050 0.0525 0.0000 0.0004 0.0008 0.0011 0.0014 0.0009 0.0050 0.0058 0.0321 0.0227 0.0675 0.0676 0.0431 0.0353 0.0673 0.0584 0.7827 0.8076 0.0009 0.0002 0.0005 0.0005 0.0023 0.0017 0.0068 0.0076 0.0390 0.0463 0.0847 0.0926 0.0513 0.0638 0.0884 0.0938 0.7262 0.6935 0.0000 0.0006 0.0023 0.0088 0.0301 0.0818 0.0496 0.0716 0.7552
BT-20 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 686 625 image if available 6653 21616 335.3 63.66 169.19 212.41 264 281 295 309 325 342 362 385 425 0.0403 871 1.098 108.24 36.69 1 0.0412 274 0.0007 66.56 7.535 0.1518 116505.0
42000000
15700000000
6090000000000
0.4550 0.1972 0.0000 0.0000 0.0006 0.0000 0.0023 0.0002 0.0068 0.0011 0.0474 0.0135 0.1064 0.0297 0.1104 0.0278 0.1437 0.0363 0.5825 0.8914 0.0000 0.0000 0.0000 0.0000 0.0012 0.0000 0.0029 0.0000 0.0239 0.0090 0.0529 0.0155 0.0543 0.0084 0.0731 0.0141 0.7917 0.9529 0.0030 0.0000 0.0120 0.0243 0.0200 0.0208 0.0430 0.1250 0.1289 0.1736 0.1548 0.2153 0.1009 0.1215 0.1419 0.1458 0.3956 0.1736 0.0017 0.0010 0.0113 0.0284 0.0825 0.1140 0.1062 0.1308 0.5240 11 13 15 21 59 135 223 332 480 0.0461 55.65 5.697 0.4308 73741.6
43100000
29900000000
23400000000000
0.4089 0.2338 0.0463 0.0015 0.1935 0.0167 0.2745 0.1152 0.1777 0.1388 0.1357 0.1962 0.0901 0.1912 0.0542 0.1307 0.0213 0.1096 0.0067 0.1001 0.0001 0.0001 0.0014 0.0005 0.0035 0.0017 0.0088 0.0064 0.0446 0.0382 0.0850 0.0684 0.0604 0.0514 0.0846 0.0704 0.7116 0.7629 0.0009 0.0006 0.0029 0.0029 0.0063 0.0060 0.0129 0.0147 0.0599 0.0658 0.1035 0.1203 0.0786 0.0886 0.1056 0.1095 0.6295 0.5914 0.0001 0.0022 0.0036 0.0127 0.0496 0.0976 0.0729 0.0936 0.6678
MDA-MB-231 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 200 513 image if available 11296 11224 660.4 94.02 95.02 136.71 543 587 617 640 661 683 708 735 774 0.1009 1133 0.918 133.74 44.91 2 0.0313 353 0.0006 79.90 7.739 0.1635 444990.0
305000000
213000000000
152000000000000
0.4251 0.2228 0.0000 0.0000 0.0005 0.0000 0.0017 0.0000 0.0042 0.0006 0.0187 0.0081 0.0399 0.0182 0.0436 0.0113 0.0656 0.0181 0.8257 0.9436 0.0000 0.0000 0.0002 0.0000 0.0006 0.0000 0.0022 0.0004 0.0107 0.0077 0.0240 0.0167 0.0219 0.0084 0.0314 0.0139 0.9090 0.9530 0.0074 0.0816 0.0173 0.0204 0.0222 0.0408 0.0937 0.2245 0.0912 0.2245 0.1307 0.2041 0.1097 0.0816 0.1233 0.1224 0.4044 0.0000 0.0016 0.0026 0.0092 0.0209 0.0527 0.0772 0.0800 0.1071 0.6486 12 16 20 27 38 53 81 138 272 0.0564 8.94 4.344 0.6275 27717.6
13300000
8080000000
5720000000000
0.4886 0.1747 0.0110 0.0020 0.0386 0.0109 0.0684 0.0288 0.1323 0.0387 0.2183 0.1107 0.1940 0.1846 0.1147 0.1166 0.1422 0.1509 0.0805 0.3568 0.0009 0.0007 0.0031 0.0037 0.0037 0.0072 0.0119 0.0120 0.0417 0.0400 0.0716 0.0744 0.0409 0.0423 0.0707 0.0596 0.7555 0.7601 0.0008 0.0004 0.0011 0.0022 0.0042 0.0043 0.0168 0.0173 0.0348 0.0381 0.0880 0.0934 0.0513 0.0510 0.0677 0.0636 0.7353 0.7297 0.0007 0.0010 0.0036 0.0116 0.0416 0.0819 0.0459 0.0714 0.7423
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 199 260 image if available 10686 24087 343.1 42.34 218.62 243.80 294 309 319 329 339 349 361 376 398 0.0560 1348 1.108 80.65 27.02 2 0.0188 201 0.0020 20.94 6.553 0.2495 119532.0
42300000
15200000000
5550000000000
0.4430 0.2105 0.0001 0.0000 0.0002 0.0000 0.0012 0.0000 0.0032 0.0005 0.0194 0.0089 0.0355 0.0176 0.0461 0.0113 0.0755 0.0211 0.8188 0.9407 0.0000 0.0000 0.0000 0.0000 0.0001 0.0000 0.0015 0.0000 0.0114 0.0086 0.0212 0.0159 0.0232 0.0077 0.0352 0.0146 0.9074 0.9532 0.0199 0.0000 0.0385 0.0000 0.0442 0.0000 0.0855 0.0000 0.0954 0.0000 0.1311 0.0000 0.1197 0.0000 0.1211 0.0000 0.3447 0.0000 0.0047 0.0098 0.0155 0.0422 0.0674 0.0986 0.1131 0.1277 0.5211 18 23 29 46 110 198 297 422 589 0.0307 46.12 5.951 0.4302 107227.0
68300000
50200000000
40800000000000
0.5298 0.1259 0.0245 0.0018 0.1127 0.0149 0.2277 0.0610 0.1750 0.0972 0.1550 0.1809 0.1245 0.2068 0.0732 0.1277 0.0609 0.1204 0.0464 0.1894 0.0000 0.0000 0.0005 0.0002 0.0017 0.0016 0.0077 0.0073 0.0415 0.0338 0.0707 0.0588 0.0495 0.0417 0.0772 0.0625 0.7513 0.7941 0.0004 0.0004 0.0010 0.0016 0.0029 0.0041 0.0139 0.0205 0.0578 0.0653 0.0903 0.1105 0.0763 0.0890 0.1087 0.1110 0.6487 0.5975 0.0001 0.0011 0.0034 0.0105 0.0471 0.0826 0.0615 0.0887 0.7050
MCF7
0
DRAQ5 1 TMRE 2 2 2 1 376 670 image if available 11475 30585 465.6 100.42 131.66 237.18 350 378 401 424 447 473 505 551 622 0.0430 1316 1.157 137.30 49.41 1 0.0297 341 0.0015 21.13 6.886 0.2666 226895.0
116000000
61700000000
34300000000000
0.4225 0.2239 0.0007 0.0000 0.0015 0.0002 0.0037 0.0005 0.0127 0.0019 0.0414 0.0147 0.0727 0.0296 0.0882 0.0265 0.1258 0.0409 0.6532 0.8857 0.0003 0.0000 0.0008 0.0000 0.0014 0.0000 0.0059 0.0002 0.0182 0.0083 0.0338 0.0145 0.0420 0.0091 0.0610 0.0147 0.8365 0.9533 0.0028 0.0121 0.0080 0.0151 0.0099 0.0302 0.0274 0.0710 0.0690 0.1480 0.0922 0.1631 0.0813 0.1329 0.1068 0.1647 0.6026 0.2628 0.0008 0.0026 0.0051 0.0240 0.0431 0.0825 0.0785 0.0990 0.6644 5 6 8 9 12 26 86 218 471 0.1403 63.23 4.504 0.5576 73585.6
57500000
53700000000
56800000000000
0.4673 0.1625 0.0887 0.0045 0.2607 0.0499 0.2554 0.2123 0.1210 0.1544 0.1082 0.1653 0.0736 0.1423 0.0413 0.0927 0.0316 0.0855 0.0195 0.0931 0.0001 0.0000 0.0005 0.0003 0.0014 0.0003 0.0066 0.0066 0.0477 0.0419 0.0761 0.0690 0.0508 0.0460 0.0878 0.0763 0.7290 0.7595 0.0001 0.0001 0.0001 0.0010 0.0019 0.0016 0.0087 0.0121 0.0598 0.0631 0.0938 0.0985 0.0624 0.0744 0.1049 0.1107 0.6681 0.6384 0.0003 0.0003 0.0015 0.0081 0.0555 0.0813 0.0601 0.0971 0.6958
MCF7
0
DRAQ5 1 TMRE 2 2 2 1 489 834 image if available 12111 18609 541.6 118.52 168.67 182.80 399 441 476 505 532 559 589 628 690 0.0564 1049 1.226 127.68 55.00 1 0.0283 343 0.0010 25.57 7.191 0.2311 307350.0
183000000
114000000000
74500000000000
0.4223 0.2210 0.0002 0.0001 0.0011 0.0003 0.0035 0.0002 0.0121 0.0018 0.0351 0.0123 0.0639 0.0223 0.0770 0.0188 0.1064 0.0282 0.7006 0.9161 0.0002 0.0000 0.0007 0.0001 0.0017 0.0002 0.0050 0.0010 0.0150 0.0084 0.0268 0.0140 0.0306 0.0093 0.0434 0.0135 0.8767 0.9536 0.0032 0.0045 0.0053 0.0061 0.0150 0.0151 0.0513 0.0363 0.0898 0.0802 0.1165 0.1104 0.1010 0.0726 0.1112 0.1104 0.5067 0.5643 0.0016 0.0023 0.0060 0.0213 0.0499 0.0789 0.0809 0.1040 0.6550 8 14 27 56 102 159 227 312 435 0.0253 65.01 6.264 0.3576 61863.3
30100000
17400000000
11500000000000
0.4777 0.1891 0.0835 0.0023 0.2306 0.0249 0.2838 0.1678 0.1513 0.1698 0.1153 0.1751 0.0782 0.1769 0.0402 0.1114 0.0146 0.0964 0.0026 0.0755 0.0004 0.0001 0.0000 0.0000 0.0005 0.0009 0.0147 0.0085 0.0655 0.0544 0.1197 0.0976 0.0848 0.0670 0.1186 0.1038 0.5959 0.6678 0.0000 0.0007 0.0011 0.0021 0.0057 0.0062 0.0239 0.0327 0.0959 0.1092 0.1534 0.1697 0.1026 0.1133 0.1390 0.1561 0.4782 0.4101 0.0001 0.0000 0.0024 0.0177 0.0832 0.1361 0.0944 0.1341 0.5320
MDA-MB-231 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 305 753 image if available 14531 31502 446.4 61.03 117.13 162.48 365 402 424 439 452 464 476 491 515 0.0488 1538 0.844 110.02 27.80 4 0.0189 274 0.0017 18.96 6.823 0.2707 202963.0
93800000
44000000000
21000000000000
0.4307 0.2135 0.0003 0.0001 0.0001 0.0000 0.0009 0.0000 0.0036 0.0001 0.0149 0.0077 0.0284 0.0166 0.0253 0.0080 0.0383 0.0128 0.8882 0.9547 0.0001 0.0001 0.0000 0.0000 0.0000 0.0000 0.0019 0.0001 0.0098 0.0077 0.0186 0.0166 0.0149 0.0080 0.0188 0.0117 0.9360 0.9558 0.0148 1.0000 0.0239 0.0000 0.0091 0.0000 0.0262 0.0000 0.0809 0.0000 0.0945 0.0000 0.0809 0.0000 0.1173 0.0000 0.5524 0.0000 0.0022 0.0070 0.0123 0.0187 0.0346 0.0523 0.0642 0.0921 0.7167 13 16 21 33 52 79 118 180 305 0.0400 19.55 4.937 0.5597 40119.5
22800000
16800000000
14600000000000
0.4801 0.1897 0.0180 0.0019 0.0684 0.0102 0.1417 0.0304 0.1389 0.0605 0.1660 0.1385 0.1648 0.1775 0.1107 0.1263 0.1041 0.1394 0.0873 0.3154 0.0012 0.0003 0.0022 0.0020 0.0034 0.0030 0.0115 0.0124 0.0463 0.0387 0.0745 0.0614 0.0495 0.0472 0.0766 0.0656 0.7348 0.7694 0.0005 0.0007 0.0024 0.0020 0.0066 0.0068 0.0187 0.0217 0.0585 0.0622 0.0953 0.1084 0.0633 0.0699 0.0954 0.0979 0.6595 0.6304 0.0004 0.0017 0.0044 0.0151 0.0498 0.0888 0.0599 0.0831 0.6968
SK-BR-3 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 518 503 image if available 15648 56021 320.9 59.50 142.33 181.99 244 279 299 315 329 341 354 368 389 0.0239 1341 0.987 126.85 36.01 1 0.0202 316 0.0015 21.65 6.855 0.2488 106538.0
36300000
12600000000
4480000000000
0.4413 0.2040 0.0005 0.0000 0.0005 0.0000 0.0020 0.0000 0.0079 0.0003 0.0295 0.0078 0.0562 0.0157 0.0615 0.0104 0.0915 0.0162 0.7503 0.9496 0.0000 0.0000 0.0000 0.0000 0.0002 0.0000 0.0023 0.0003 0.0109 0.0075 0.0242 0.0143 0.0210 0.0081 0.0316 0.0119 0.9098 0.9580 0.0090 0.0536 0.0157 0.0179 0.0336 0.1429 0.0745 0.2143 0.1272 0.1429 0.1557 0.1607 0.1429 0.1071 0.1597 0.0357 0.2818 0.1250 0.0008 0.0025 0.0050 0.0158 0.0410 0.0684 0.0815 0.0977 0.6873 8 10 12 18 51 108 178 269 424 0.1076 16.66 4.969 0.5393 53375.8
26600000
15300000000
9680000000000
0.3694 0.2725 0.0166 0.0013 0.1012 0.0060 0.2168 0.0361 0.1910 0.0912 0.1770 0.1724 0.1403 0.2115 0.0824 0.1547 0.0457 0.1475 0.0291 0.1792 0.0006 0.0002 0.0006 0.0006 0.0027 0.0015 0.0085 0.0065 0.0354 0.0299 0.0682 0.0565 0.0555 0.0459 0.0719 0.0641 0.7567 0.7947 0.0005 0.0005 0.0022 0.0022 0.0040 0.0048 0.0126 0.0154 0.0463 0.0551 0.0837 0.0934 0.0695 0.0743 0.0862 0.0911 0.6950 0.6633 0.0005 0.0017 0.0041 0.0114 0.0416 0.0737 0.0613 0.0797 0.7260
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 923 749 image if available 18485 19144 337.4 48.91 148.53 162.19 268 300 318 331 344 355 367 380 396 0.0705 1349 1.142 100.72 39.20 2 0.0147 271 0.0025 9.90 6.327 0.3429 116234.0
40800000
14500000000
5230000000000
0.4218 0.2181 0.0005 0.0000 0.0012 0.0001 0.0027 0.0001 0.0083 0.0008 0.0174 0.0071 0.0285 0.0145 0.0316 0.0074 0.0551 0.0119 0.8546 0.9581 0.0001 0.0000 0.0000 0.0001 0.0005 0.0001 0.0022 0.0008 0.0085 0.0071 0.0136 0.0145 0.0122 0.0074 0.0186 0.0119 0.9443 0.9581 0.0326 0.0000 0.0692 0.0000 0.0794 0.0000 0.1090 0.0000 0.1517 0.0000 0.1415 0.0000 0.1395 0.0000 0.1446 0.0000 0.1324 0.0000 0.0028 0.0050 0.0091 0.0138 0.0293 0.0412 0.0457 0.0737 0.7793 23 31 42 57 77 109 167 256 387 0.0183 13.36 5.441 0.5104 48364.8
22700000
12800000000
8140000000000
0.3890 0.2609 0.0233 0.0013 0.0952 0.0085 0.1700 0.0530 0.1578 0.1011 0.1966 0.1512 0.1445 0.1702 0.0908 0.1386 0.0714 0.1404 0.0504 0.2358 0.0001 0.0003 0.0008 0.0009 0.0026 0.0044 0.0128 0.0124 0.0492 0.0417 0.0708 0.0661 0.0547 0.0448 0.0827 0.0706 0.7262 0.7587 0.0007 0.0006 0.0009 0.0017 0.0035 0.0058 0.0196 0.0235 0.0581 0.0707 0.0989 0.0946 0.0629 0.0773 0.0941 0.1006 0.6612 0.6252 0.0000 0.0010 0.0043 0.0159 0.0522 0.0864 0.0570 0.0870 0.6963
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 1097 888 image if available 12238 26075 289.7 37.50 189.36 227.04 244 259 270 279 288 297 306 319 339 0.0439 1145 0.830 88.09 22.20 1 0.0187 229 0.0028 13.76 6.262 0.2992 85311.3
25500000
7770000000
2410000000000
0.4323 0.2203 0.0001 0.0000 0.0006 0.0000 0.0020 0.0000 0.0060 0.0003 0.0185 0.0078 0.0396 0.0156 0.0439 0.0098 0.0748 0.0169 0.8146 0.9496 0.0000 0.0000 0.0001 0.0000 0.0004 0.0000 0.0019 0.0001 0.0111 0.0076 0.0227 0.0147 0.0220 0.0071 0.0372 0.0112 0.9046 0.9593 0.0133 0.0000 0.0200 0.0000 0.0333 0.0000 0.0765 0.0000 0.1109 0.0000 0.1408 0.0000 0.1264 0.0000 0.1574 0.0000 0.3215 0.0000 0.0025 0.0088 0.0142 0.0239 0.0616 0.0902 0.0999 0.1291 0.5696 14 17 21 38 82 149 243 368 535 0.0346 41.52 5.730 0.4531 87402.9
53700000
38800000000
31400000000000
0.4360 0.2156 0.0618 0.0023 0.2087 0.0236 0.2420 0.1370 0.1346 0.1541 0.1098 0.1754 0.0927 0.1578 0.0590 0.0979 0.0495 0.0906 0.0418 0.1614 0.0001 0.0003 0.0003 0.0006 0.0015 0.0013 0.0103 0.0092 0.0495 0.0407 0.0808 0.0715 0.0648 0.0501 0.0944 0.0787 0.6983 0.7478 0.0000 0.0003 0.0007 0.0015 0.0026 0.0033 0.0159 0.0223 0.0664 0.0710 0.1136 0.1319 0.0845 0.0978 0.1225 0.1311 0.5939 0.5409 0.0004 0.0007 0.0021 0.0134 0.0562 0.0948 0.0755 0.1060 0.6510
SK-BR-3 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 969 728 image if available 16378 49009 195.5 37.68 203.96 331.62 151 169 180 189 198 206 215 226 241 0.0278 1362 1.188 93.09 34.48 1 0.0143 235 0.0032 12.80 6.161 0.3225 39638.5
8270000
1770000000
387000000000
0.4222 0.2262 0.0002 0.0000 0.0012 0.0000 0.0037 0.0000 0.0129 0.0003 0.0346 0.0080 0.0661 0.0181 0.0824 0.0160 0.1152 0.0268 0.6836 0.9309 0.0001 0.0000 0.0003 0.0000 0.0008 0.0000 0.0036 0.0001 0.0120 0.0068 0.0260 0.0139 0.0283 0.0069 0.0418 0.0107 0.8870 0.9616 0.0089 0.0576 0.0166 0.0995 0.0426 0.1047 0.0736 0.1780 0.1192 0.1937 0.1473 0.1675 0.1256 0.0733 0.1456 0.0890 0.3206 0.0366 0.0012 0.0027 0.0072 0.0202 0.0501 0.0834 0.0821 0.1197 0.6333 7 8 10 12 17 54 192 390 701 0.1432 35.53 4.788 0.5519 151568.0
149000000
169000000000
211000000000000
0.4292 0.2197 0.0529 0.0035 0.2034 0.0131 0.2775 0.1127 0.1544 0.1604 0.1262 0.2014 0.0909 0.1979 0.0516 0.1081 0.0322 0.1003 0.0110 0.1027 0.0001 0.0001 0.0003 0.0001 0.0010 0.0003 0.0081 0.0057 0.0395 0.0371 0.0691 0.0641 0.0487 0.0414 0.0700 0.0648 0.7633 0.7864 0.0004 0.0003 0.0011 0.0011 0.0028 0.0036 0.0129 0.0138 0.0452 0.0466 0.0753 0.0825 0.0565 0.0561 0.0729 0.0789 0.7329 0.7170 0.0001 0.0013 0.0022 0.0102 0.0423 0.0730 0.0512 0.0723 0.7473