High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1044 | 317 | | 12277 | 27737 | 337.8 | 80.82 | 126.25 | 196.68 | 245 | 268 | 287 | 306 | 326 | 349 | 374 | 406 | 447 | 0.0408 | 1133 | 1.055 | 137.89 | 53.26 | 1 | 0.0307 | 377 | 0.0011 | 31.32 | 7.089 | 0.2146 | 120627.0 | 45500000 | 18100000000 | 7610000000000 | 0.4436 | 0.2108 | 0.0003 | 0.0000 | 0.0014 | 0.0000 | 0.0075 | 0.0005 | 0.0193 | 0.0028 | 0.0768 | 0.0156 | 0.1399 | 0.0382 | 0.1395 | 0.0401 | 0.1655 | 0.0606 | 0.4499 | 0.8421 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0066 | 0.0003 | 0.0331 | 0.0088 | 0.0616 | 0.0201 | 0.0593 | 0.0159 | 0.0849 | 0.0256 | 0.7518 | 0.9293 | 0.0008 | 0.0082 | 0.0036 | 0.0192 | 0.0097 | 0.0549 | 0.0449 | 0.1152 | 0.1237 | 0.1578 | 0.1556 | 0.1852 | 0.1144 | 0.1221 | 0.1516 | 0.1221 | 0.3957 | 0.2154 | 0.0007 | 0.0024 | 0.0049 | 0.0284 | 0.0649 | 0.1105 | 0.0822 | 0.1107 | 0.5952 | 5 | 7 | 8 | 10 | 13 | 46 | 142 | 252 | 404 | 0.0900 | 13.02 | 4.139 | 0.4903 | 54618.6 | 33500000 | 26000000000 | 23800000000000 | 0.3964 | 0.2554 | 0.0519 | 0.0030 | 0.2024 | 0.0144 | 0.3281 | 0.0926 | 0.1490 | 0.1590 | 0.1211 | 0.2328 | 0.0760 | 0.2176 | 0.0384 | 0.1206 | 0.0256 | 0.0893 | 0.0075 | 0.0708 | 0.0000 | 0.0000 | 0.0002 | 0.0003 | 0.0009 | 0.0006 | 0.0045 | 0.0028 | 0.0333 | 0.0259 | 0.0610 | 0.0514 | 0.0479 | 0.0383 | 0.0731 | 0.0617 | 0.7792 | 0.8190 | 0.0002 | 0.0001 | 0.0001 | 0.0012 | 0.0011 | 0.0016 | 0.0074 | 0.0108 | 0.0452 | 0.0500 | 0.0802 | 0.0994 | 0.0683 | 0.0688 | 0.0954 | 0.1041 | 0.7019 | 0.6639 | 0.0001 | 0.0001 | 0.0005 | 0.0061 | 0.0373 | 0.0712 | 0.0564 | 0.0847 | 0.7437 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 425 | 155 | | 10526 | 21020 | 318.4 | 61.96 | 206.32 | 250.19 | 242 | 266 | 284 | 299 | 314 | 330 | 347 | 369 | 404 | 0.0516 | 1084 | 1.093 | 105.19 | 36.12 | 1 | 0.0249 | 262 | 0.0006 | 81.62 | 7.746 | 0.1363 | 105224.0 | 36000000 | 12800000000 | 4660000000000 | 0.4431 | 0.2108 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0026 | 0.0000 | 0.0134 | 0.0015 | 0.0534 | 0.0127 | 0.1190 | 0.0291 | 0.1293 | 0.0329 | 0.1742 | 0.0536 | 0.5079 | 0.8701 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0007 | 0.0233 | 0.0087 | 0.0553 | 0.0181 | 0.0559 | 0.0145 | 0.0879 | 0.0257 | 0.7716 | 0.9324 | 0.0047 | 0.0280 | 0.0142 | 0.0592 | 0.0272 | 0.0592 | 0.0781 | 0.1526 | 0.1230 | 0.2087 | 0.1715 | 0.2150 | 0.1212 | 0.1277 | 0.1467 | 0.0779 | 0.3134 | 0.0717 | 0.0012 | 0.0020 | 0.0075 | 0.0315 | 0.0817 | 0.1365 | 0.1121 | 0.1303 | 0.4971 | 16 | 20 | 26 | 45 | 90 | 165 | 257 | 379 | 569 | 0.0265 | 51.36 | 6.104 | 0.4177 | 105162.0 | 74300000 | 63500000000 | 62100000000000 | 0.4677 | 0.1545 | 0.0348 | 0.0018 | 0.1515 | 0.0098 | 0.2413 | 0.0665 | 0.1600 | 0.1355 | 0.1658 | 0.1909 | 0.1109 | 0.1899 | 0.0702 | 0.1368 | 0.0428 | 0.1209 | 0.0227 | 0.1479 | 0.0001 | 0.0002 | 0.0006 | 0.0006 | 0.0021 | 0.0007 | 0.0075 | 0.0067 | 0.0513 | 0.0425 | 0.0842 | 0.0699 | 0.0615 | 0.0534 | 0.0927 | 0.0778 | 0.7001 | 0.7481 | 0.0000 | 0.0002 | 0.0017 | 0.0024 | 0.0040 | 0.0065 | 0.0161 | 0.0168 | 0.0672 | 0.0746 | 0.1113 | 0.1207 | 0.0727 | 0.0793 | 0.1113 | 0.1116 | 0.6157 | 0.5879 | 0.0003 | 0.0009 | 0.0029 | 0.0128 | 0.0565 | 0.0983 | 0.0684 | 0.1010 | 0.6588 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 717 | 772 | | 5044 | 13779 | 301.7 | 59.20 | 210.76 | 220.75 | 231 | 249 | 265 | 280 | 295 | 312 | 331 | 354 | 385 | 0.0589 | 812 | 0.776 | 118.60 | 32.65 | 1 | 0.0632 | 319 | 0.0007 | 72.96 | 7.469 | 0.1451 | 94502.0 | 30700000 | 10300000000 | 3580000000000 | 0.4636 | 0.1931 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0000 | 0.0145 | 0.0006 | 0.0751 | 0.0121 | 0.1252 | 0.0311 | 0.1304 | 0.0313 | 0.1693 | 0.0459 | 0.4797 | 0.8791 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0044 | 0.0000 | 0.0323 | 0.0096 | 0.0650 | 0.0212 | 0.0617 | 0.0156 | 0.0939 | 0.0258 | 0.7425 | 0.9278 | 0.0060 | 0.0074 | 0.0072 | 0.0148 | 0.0241 | 0.0889 | 0.0869 | 0.1778 | 0.1351 | 0.1926 | 0.1966 | 0.2296 | 0.1230 | 0.1037 | 0.1460 | 0.1185 | 0.2750 | 0.0667 | 0.0004 | 0.0009 | 0.0051 | 0.0381 | 0.0908 | 0.1422 | 0.0934 | 0.1285 | 0.5004 | 12 | 16 | 29 | 71 | 138 | 216 | 302 | 388 | 517 | 0.0184 | 66.02 | 6.381 | 0.3575 | 93147.7 | 54300000 | 38200000000 | 31100000000000 | 0.5593 | 0.0982 | 0.0360 | 0.0028 | 0.1517 | 0.0183 | 0.2992 | 0.0785 | 0.1891 | 0.1391 | 0.1447 | 0.1813 | 0.0976 | 0.2120 | 0.0429 | 0.1411 | 0.0277 | 0.1141 | 0.0111 | 0.1128 | 0.0005 | 0.0000 | 0.0006 | 0.0013 | 0.0024 | 0.0029 | 0.0090 | 0.0067 | 0.0485 | 0.0391 | 0.0883 | 0.0705 | 0.0680 | 0.0561 | 0.1104 | 0.0882 | 0.6724 | 0.7352 | 0.0002 | 0.0007 | 0.0010 | 0.0007 | 0.0043 | 0.0064 | 0.0151 | 0.0203 | 0.0661 | 0.0835 | 0.1350 | 0.1546 | 0.0965 | 0.1018 | 0.1321 | 0.1450 | 0.5497 | 0.4870 | 0.0002 | 0.0009 | 0.0032 | 0.0112 | 0.0580 | 0.1055 | 0.0852 | 0.1259 | 0.6100 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 968 | 293 | | 9056 | 13099 | 516.1 | 88.24 | 114.69 | 251.28 | 396 | 459 | 491 | 512 | 529 | 545 | 562 | 583 | 612 | 0.0837 | 1097 | 0.940 | 103.45 | 28.16 | 6 | 0.0282 | 255 | 0.0009 | 51.99 | 7.361 | 0.1986 | 274112.0 | 149000000 | 82200000000 | 46100000000000 | 0.4370 | 0.2059 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0050 | 0.0007 | 0.0278 | 0.0152 | 0.0543 | 0.0277 | 0.0482 | 0.0150 | 0.0760 | 0.0288 | 0.7879 | 0.9127 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0007 | 0.0168 | 0.0152 | 0.0317 | 0.0272 | 0.0203 | 0.0143 | 0.0351 | 0.0258 | 0.8942 | 0.9168 | 0.0106 | 0.0000 | 0.0080 | 0.0000 | 0.0359 | 0.0000 | 0.0638 | 0.0000 | 0.1237 | 0.0000 | 0.1463 | 0.0000 | 0.1077 | 0.0000 | 0.1303 | 0.0000 | 0.3737 | 0.0000 | 0.0015 | 0.0017 | 0.0063 | 0.0160 | 0.0428 | 0.0699 | 0.0713 | 0.1070 | 0.6836 | 8 | 10 | 12 | 14 | 20 | 34 | 63 | 120 | 305 | 0.0778 | 7.79 | 3.212 | 0.5546 | 76290.7 | 93700000 | 170000000000 | 429000000000000 | 0.7394 | 0.0357 | 0.0196 | 0.0006 | 0.0825 | 0.0106 | 0.1649 | 0.0417 | 0.1872 | 0.0636 | 0.1702 | 0.1514 | 0.1584 | 0.2125 | 0.1152 | 0.1383 | 0.0654 | 0.1383 | 0.0366 | 0.2430 | 0.0003 | 0.0000 | 0.0019 | 0.0013 | 0.0083 | 0.0037 | 0.0156 | 0.0088 | 0.0568 | 0.0470 | 0.0879 | 0.0948 | 0.0632 | 0.0564 | 0.0959 | 0.0866 | 0.6702 | 0.7013 | 0.0008 | 0.0005 | 0.0004 | 0.0014 | 0.0059 | 0.0028 | 0.0184 | 0.0229 | 0.0675 | 0.0744 | 0.1010 | 0.1155 | 0.0700 | 0.0734 | 0.1014 | 0.1001 | 0.6345 | 0.6090 | 0.0015 | 0.0018 | 0.0041 | 0.0170 | 0.0595 | 0.0983 | 0.0698 | 0.0953 | 0.6526 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 976 | 656 | | 13290 | 29012 | 350.5 | 83.54 | 117.42 | 202.47 | 252 | 284 | 306 | 327 | 348 | 369 | 393 | 419 | 457 | 0.0458 | 1328 | 1.206 | 145.66 | 51.35 | 3 | 0.0266 | 354 | 0.0009 | 33.81 | 7.228 | 0.1932 | 129853.0 | 50400000 | 20400000000 | 8570000000000 | 0.4626 | 0.1869 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0137 | 0.0009 | 0.0626 | 0.0154 | 0.1394 | 0.0357 | 0.1429 | 0.0364 | 0.1618 | 0.0560 | 0.4786 | 0.8556 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0047 | 0.0002 | 0.0239 | 0.0104 | 0.0583 | 0.0216 | 0.0527 | 0.0167 | 0.0693 | 0.0259 | 0.7910 | 0.9253 | 0.0016 | 0.0134 | 0.0070 | 0.0202 | 0.0147 | 0.0353 | 0.0609 | 0.1109 | 0.1230 | 0.1681 | 0.1707 | 0.1983 | 0.1145 | 0.1059 | 0.1486 | 0.1345 | 0.3589 | 0.2134 | 0.0002 | 0.0012 | 0.0066 | 0.0185 | 0.0678 | 0.1107 | 0.0917 | 0.1206 | 0.5827 | 6 | 7 | 9 | 10 | 12 | 24 | 88 | 206 | 406 | 0.1454 | 15.57 | 3.922 | 0.5837 | 54782.0 | 35700000 | 27800000000 | 24300000000000 | 0.5329 | 0.1352 | 0.0637 | 0.0030 | 0.1850 | 0.0394 | 0.2305 | 0.1421 | 0.1607 | 0.1285 | 0.1562 | 0.1739 | 0.0925 | 0.1834 | 0.0652 | 0.1156 | 0.0326 | 0.0940 | 0.0136 | 0.1201 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0018 | 0.0013 | 0.0098 | 0.0088 | 0.0421 | 0.0384 | 0.0678 | 0.0575 | 0.0453 | 0.0456 | 0.0680 | 0.0641 | 0.7645 | 0.7842 | 0.0000 | 0.0003 | 0.0004 | 0.0007 | 0.0017 | 0.0025 | 0.0116 | 0.0124 | 0.0523 | 0.0544 | 0.0850 | 0.0971 | 0.0615 | 0.0646 | 0.0847 | 0.0903 | 0.7028 | 0.6776 | 0.0004 | 0.0005 | 0.0019 | 0.0076 | 0.0494 | 0.0725 | 0.0487 | 0.0795 | 0.7395 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 994 | 366 | | 5578 | 9502 | 439.0 | 109.23 | 7.27 | 7.81 | 292 | 342 | 380 | 410 | 440 | 471 | 499 | 532 | 577 | 0.0764 | 726 | 0.939 | 87.10 | 28.18 | 1 | 0.0446 | 249 | 0.0007 | 54.37 | 7.463 | 0.1610 | 204683.0 | 101000000 | 51800000000 | 27900000000000 | 0.4190 | 0.2212 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0035 | 0.0004 | 0.0227 | 0.0026 | 0.0796 | 0.0200 | 0.1332 | 0.0381 | 0.1486 | 0.0495 | 0.1674 | 0.0707 | 0.4438 | 0.8187 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0004 | 0.0055 | 0.0021 | 0.0249 | 0.0145 | 0.0386 | 0.0203 | 0.0420 | 0.0202 | 0.0598 | 0.0259 | 0.8277 | 0.9167 | 0.0025 | 0.0150 | 0.0083 | 0.0300 | 0.0108 | 0.0936 | 0.0717 | 0.1685 | 0.1350 | 0.1648 | 0.1983 | 0.1985 | 0.1250 | 0.0749 | 0.1433 | 0.0599 | 0.3050 | 0.1948 | 0.0011 | 0.0014 | 0.0018 | 0.0164 | 0.0513 | 0.0969 | 0.0840 | 0.1033 | 0.6439 | 3 | 4 | 5 | 6 | 6 | 7 | 8 | 8 | 10 | 0.3430 | 0.51 | 1.198 | 0.7294 | 113.9 | 6884.51 | 785459 | 106000000 | 0.5832 | 0.1225 | 0.0192 | 0.0019 | 0.0770 | 0.0156 | 0.1579 | 0.0462 | 0.2263 | 0.1039 | 0.2280 | 0.1979 | 0.1695 | 0.2473 | 0.0885 | 0.2176 | 0.0290 | 0.1308 | 0.0047 | 0.0389 | 0.0061 | 0.0001 | 0.0245 | 0.0052 | 0.0678 | 0.0214 | 0.1121 | 0.0524 | 0.1595 | 0.1246 | 0.1671 | 0.1799 | 0.1649 | 0.2137 | 0.1572 | 0.2103 | 0.1408 | 0.1925 | 0.1745 | 0.1950 | 0.1707 | 0.1376 | 0.1329 | 0.1217 | 0.1097 | 0.1088 | 0.0929 | 0.0945 | 0.0843 | 0.0801 | 0.0659 | 0.0748 | 0.0751 | 0.0786 | 0.0940 | 0.1088 | 0.0231 | 0.0695 | 0.1299 | 0.1560 | 0.1619 | 0.1493 | 0.1157 | 0.0965 | 0.0981 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 283 | 97 | | 3964 | 10522 | 352.2 | 81.30 | 461.34 | 382.37 | 252 | 288 | 313 | 334 | 354 | 372 | 392 | 416 | 452 | 0.0657 | 691 | 0.753 | 95.27 | 24.08 | 1 | 0.0658 | 261 | 0.0006 | 102.74 | 7.612 | 0.1258 | 130633.0 | 50600000 | 20400000000 | 8530000000000 | 0.4023 | 0.2386 | 0.0008 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0000 | 0.0179 | 0.0014 | 0.0550 | 0.0209 | 0.1072 | 0.0390 | 0.1228 | 0.0329 | 0.1454 | 0.0549 | 0.5458 | 0.8510 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0061 | 0.0013 | 0.0223 | 0.0154 | 0.0444 | 0.0260 | 0.0471 | 0.0172 | 0.0640 | 0.0262 | 0.8145 | 0.9139 | 0.0000 | 0.0109 | 0.0100 | 0.0109 | 0.0242 | 0.0217 | 0.0627 | 0.1033 | 0.1296 | 0.1467 | 0.1553 | 0.1413 | 0.1254 | 0.1196 | 0.1538 | 0.1033 | 0.3390 | 0.3424 | 0.0010 | 0.0035 | 0.0049 | 0.0233 | 0.0673 | 0.1054 | 0.1049 | 0.1242 | 0.5656 | 46 | 92 | 175 | 276 | 376 | 494 | 622 | 777 | 1000 | 0.0020 | 93.98 | 7.546 | 0.2428 | 359026.0 | 355000000 | 407000000000 | 521000000000000 | 0.5626 | 0.1363 | 0.0068 | 0.0015 | 0.0542 | 0.0057 | 0.1423 | 0.0121 | 0.1725 | 0.0508 | 0.1725 | 0.1309 | 0.1744 | 0.1967 | 0.1072 | 0.1517 | 0.0930 | 0.1565 | 0.0770 | 0.2940 | 0.0004 | 0.0000 | 0.0039 | 0.0011 | 0.0049 | 0.0030 | 0.0161 | 0.0105 | 0.0447 | 0.0377 | 0.0709 | 0.0692 | 0.0629 | 0.0510 | 0.0765 | 0.0729 | 0.7196 | 0.7546 | 0.0008 | 0.0007 | 0.0027 | 0.0023 | 0.0065 | 0.0073 | 0.0220 | 0.0293 | 0.0578 | 0.0676 | 0.0957 | 0.1119 | 0.0774 | 0.0916 | 0.1013 | 0.1196 | 0.6358 | 0.5696 | 0.0002 | 0.0022 | 0.0038 | 0.0146 | 0.0510 | 0.0864 | 0.0649 | 0.0858 | 0.6910 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 560 | 270 | | 5568 | 18268 | 433.5 | 92.93 | 137.20 | 136.94 | 324 | 352 | 376 | 397 | 422 | 446 | 477 | 510 | 564 | 0.0541 | 989 | 1.182 | 95.60 | 36.50 | 1 | 0.0449 | 250 | 0.0012 | 33.93 | 7.010 | 0.1946 | 196527.0 | 93100000 | 46100000000 | 23700000000000 | 0.4332 | 0.2136 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0020 | 0.0002 | 0.0140 | 0.0011 | 0.0717 | 0.0192 | 0.1259 | 0.0400 | 0.1320 | 0.0390 | 0.1664 | 0.0581 | 0.4877 | 0.8422 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0064 | 0.0000 | 0.0304 | 0.0128 | 0.0556 | 0.0229 | 0.0530 | 0.0152 | 0.0754 | 0.0265 | 0.7781 | 0.9225 | 0.0031 | 0.0070 | 0.0071 | 0.0245 | 0.0224 | 0.0280 | 0.0671 | 0.1294 | 0.1180 | 0.1993 | 0.1699 | 0.2133 | 0.1282 | 0.1084 | 0.1506 | 0.1434 | 0.3337 | 0.1469 | 0.0020 | 0.0016 | 0.0052 | 0.0290 | 0.0708 | 0.1225 | 0.0982 | 0.1301 | 0.5406 | 20 | 35 | 55 | 76 | 97 | 124 | 159 | 209 | 290 | 0.0125 | 11.31 | 5.396 | 0.4946 | 37572.9 | 16400000 | 9620000000 | 6730000000000 | 0.5560 | 0.1152 | 0.0139 | 0.0011 | 0.0448 | 0.0071 | 0.1227 | 0.0245 | 0.1370 | 0.0568 | 0.1652 | 0.1234 | 0.1675 | 0.1608 | 0.1217 | 0.1315 | 0.1118 | 0.1516 | 0.1154 | 0.3433 | 0.0013 | 0.0001 | 0.0016 | 0.0026 | 0.0052 | 0.0039 | 0.0169 | 0.0131 | 0.0498 | 0.0475 | 0.0829 | 0.0732 | 0.0663 | 0.0599 | 0.0861 | 0.0802 | 0.6900 | 0.7194 | 0.0015 | 0.0007 | 0.0029 | 0.0034 | 0.0061 | 0.0079 | 0.0209 | 0.0274 | 0.0672 | 0.0758 | 0.1087 | 0.1185 | 0.0846 | 0.0902 | 0.1045 | 0.1152 | 0.6036 | 0.5609 | 0.0021 | 0.0021 | 0.0044 | 0.0190 | 0.0539 | 0.0970 | 0.0768 | 0.0992 | 0.6453 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 634 | 828 | | 6200 | 7303 | 203.7 | 43.18 | 209.83 | 149.65 | 154 | 167 | 178 | 188 | 198 | 208 | 221 | 237 | 262 | 0.1191 | 870 | 1.113 | 92.59 | 26.68 | 1 | 0.0353 | 219 | 0.0012 | 41.78 | 7.014 | 0.1838 | 43340.5 | 9650000 | 2250000000 | 547000000000 | 0.4334 | 0.2122 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0031 | 0.0003 | 0.0157 | 0.0007 | 0.0711 | 0.0174 | 0.1256 | 0.0376 | 0.1517 | 0.0398 | 0.1830 | 0.0615 | 0.4490 | 0.8428 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0002 | 0.0066 | 0.0000 | 0.0335 | 0.0122 | 0.0534 | 0.0229 | 0.0720 | 0.0143 | 0.0964 | 0.0265 | 0.7359 | 0.9239 | 0.0059 | 0.0102 | 0.0088 | 0.0307 | 0.0137 | 0.0648 | 0.0715 | 0.1160 | 0.1538 | 0.1945 | 0.1851 | 0.1672 | 0.1303 | 0.1297 | 0.1538 | 0.1229 | 0.2772 | 0.1638 | 0.0025 | 0.0040 | 0.0087 | 0.0395 | 0.0938 | 0.1242 | 0.1177 | 0.1409 | 0.4687 | 40 | 70 | 103 | 137 | 177 | 225 | 280 | 343 | 426 | 0.0014 | 93.66 | 7.304 | 0.1920 | 66420.4 | 25900000 | 11500000000 | 5580000000000 | 0.5796 | 0.1202 | 0.0390 | 0.0023 | 0.1851 | 0.0148 | 0.2695 | 0.0760 | 0.1802 | 0.1442 | 0.1420 | 0.1832 | 0.1063 | 0.2186 | 0.0446 | 0.1454 | 0.0219 | 0.1134 | 0.0114 | 0.1021 | 0.0005 | 0.0007 | 0.0029 | 0.0009 | 0.0084 | 0.0050 | 0.0260 | 0.0176 | 0.0825 | 0.0686 | 0.1372 | 0.1114 | 0.1075 | 0.0997 | 0.1319 | 0.1233 | 0.5030 | 0.5729 | 0.0019 | 0.0034 | 0.0051 | 0.0059 | 0.0179 | 0.0206 | 0.0451 | 0.0677 | 0.1147 | 0.1290 | 0.1683 | 0.1986 | 0.1306 | 0.1226 | 0.1446 | 0.1466 | 0.3719 | 0.3055 | 0.0003 | 0.0064 | 0.0121 | 0.0359 | 0.0978 | 0.1547 | 0.1134 | 0.1556 | 0.4239 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 484 | 784 | | 7556 | 23389 | 282.7 | 59.70 | 166.78 | 196.60 | 210 | 231 | 247 | 262 | 276 | 293 | 311 | 334 | 366 | 0.0490 | 1145 | 1.213 | 102.16 | 38.05 | 1 | 0.0335 | 253 | 0.0006 | 75.57 | 7.614 | 0.1408 | 83467.9 | 25700000 | 8220000000 | 2730000000000 | 0.4316 | 0.2191 | 0.0002 | 0.0003 | 0.0006 | 0.0001 | 0.0020 | 0.0000 | 0.0170 | 0.0010 | 0.0677 | 0.0158 | 0.1511 | 0.0377 | 0.1521 | 0.0373 | 0.1708 | 0.0609 | 0.4384 | 0.8469 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0056 | 0.0004 | 0.0270 | 0.0106 | 0.0679 | 0.0232 | 0.0670 | 0.0160 | 0.0934 | 0.0265 | 0.7377 | 0.9233 | 0.0044 | 0.0233 | 0.0110 | 0.0233 | 0.0242 | 0.0631 | 0.0696 | 0.1728 | 0.1275 | 0.1960 | 0.1758 | 0.2060 | 0.1231 | 0.1063 | 0.1407 | 0.1296 | 0.3238 | 0.0797 | 0.0012 | 0.0035 | 0.0092 | 0.0372 | 0.0773 | 0.1330 | 0.1108 | 0.1304 | 0.4975 | 13 | 15 | 19 | 28 | 65 | 144 | 233 | 329 | 451 | 0.0382 | 38.04 | 5.638 | 0.4378 | 66466.3 | 34900000 | 21500000000 | 14900000000000 | 0.4729 | 0.1465 | 0.0850 | 0.0014 | 0.2309 | 0.0230 | 0.3225 | 0.1754 | 0.1274 | 0.1961 | 0.0928 | 0.2081 | 0.0531 | 0.1530 | 0.0330 | 0.0985 | 0.0279 | 0.0639 | 0.0274 | 0.0806 | 0.0000 | 0.0000 | 0.0005 | 0.0004 | 0.0009 | 0.0009 | 0.0084 | 0.0061 | 0.0473 | 0.0406 | 0.0840 | 0.0716 | 0.0667 | 0.0537 | 0.1009 | 0.0862 | 0.6912 | 0.7406 | 0.0001 | 0.0001 | 0.0013 | 0.0011 | 0.0031 | 0.0056 | 0.0161 | 0.0217 | 0.0677 | 0.0724 | 0.1058 | 0.1268 | 0.0903 | 0.0954 | 0.1290 | 0.1366 | 0.5867 | 0.5403 | 0.0000 | 0.0011 | 0.0013 | 0.0122 | 0.0536 | 0.0968 | 0.0807 | 0.1121 | 0.6423 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 376 | 815 | | 6277 | 23826 | 431.4 | 82.01 | 114.95 | 189.20 | 331 | 361 | 383 | 403 | 426 | 447 | 473 | 503 | 544 | 0.0434 | 1033 | 0.842 | 82.28 | 28.16 | 1 | 0.0394 | 247 | 0.0009 | 43.90 | 7.226 | 0.1745 | 192840.0 | 89200000 | 42600000000 | 20900000000000 | 0.4504 | 0.2050 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0030 | 0.0000 | 0.0159 | 0.0007 | 0.0597 | 0.0143 | 0.1101 | 0.0347 | 0.1238 | 0.0286 | 0.1574 | 0.0475 | 0.5295 | 0.8742 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0071 | 0.0000 | 0.0301 | 0.0117 | 0.0512 | 0.0268 | 0.0508 | 0.0136 | 0.0737 | 0.0265 | 0.7865 | 0.9214 | 0.0030 | 0.0329 | 0.0071 | 0.0197 | 0.0243 | 0.0526 | 0.0943 | 0.1645 | 0.1400 | 0.2368 | 0.1684 | 0.1711 | 0.1197 | 0.1184 | 0.1379 | 0.1184 | 0.3053 | 0.0855 | 0.0007 | 0.0023 | 0.0119 | 0.0250 | 0.0781 | 0.1153 | 0.0982 | 0.1255 | 0.5430 | 9 | 11 | 14 | 17 | 24 | 44 | 100 | 202 | 343 | 0.0536 | 32.28 | 4.983 | 0.5358 | 49009.5 | 35200000 | 34900000000 | 42600000000000 | 0.5156 | 0.1405 | 0.0766 | 0.0042 | 0.1959 | 0.0170 | 0.2844 | 0.1298 | 0.1485 | 0.1714 | 0.1248 | 0.1956 | 0.0821 | 0.1646 | 0.0450 | 0.0980 | 0.0269 | 0.1018 | 0.0158 | 0.1177 | 0.0000 | 0.0004 | 0.0003 | 0.0002 | 0.0023 | 0.0016 | 0.0088 | 0.0101 | 0.0504 | 0.0422 | 0.0802 | 0.0661 | 0.0538 | 0.0498 | 0.0854 | 0.0812 | 0.7189 | 0.7485 | 0.0003 | 0.0005 | 0.0008 | 0.0009 | 0.0041 | 0.0030 | 0.0112 | 0.0163 | 0.0573 | 0.0598 | 0.0870 | 0.0918 | 0.0671 | 0.0702 | 0.0950 | 0.1061 | 0.6771 | 0.6513 | 0.0006 | 0.0010 | 0.0016 | 0.0108 | 0.0544 | 0.0823 | 0.0603 | 0.0952 | 0.6936 | ||
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 187 | 499 | | 5159 | 11813 | 530.2 | 150.73 | 46.53 | 99.31 | 336 | 405 | 473 | 515 | 555 | 600 | 635 | 664 | 696 | 0.0781 | 923 | 1.105 | 73.82 | 25.55 | 4 | 0.0382 | 197 | 0.0006 | 44.92 | 7.570 | 0.1925 | 303806.0 | 182000000 | 112000000000 | 70800000000000 | 0.3690 | 0.2568 | 0.0020 | 0.0000 | 0.0029 | 0.0000 | 0.0069 | 0.0004 | 0.0167 | 0.0024 | 0.0587 | 0.0163 | 0.0953 | 0.0308 | 0.0843 | 0.0238 | 0.1059 | 0.0400 | 0.6273 | 0.8863 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0025 | 0.0021 | 0.0185 | 0.0146 | 0.0285 | 0.0275 | 0.0217 | 0.0173 | 0.0307 | 0.0266 | 0.8966 | 0.9119 | 0.0019 | 0.0635 | 0.0052 | 0.0476 | 0.0110 | 0.1270 | 0.0213 | 0.1429 | 0.0549 | 0.0635 | 0.0614 | 0.1270 | 0.0627 | 0.0952 | 0.1008 | 0.1270 | 0.6807 | 0.2063 | 0.0010 | 0.0024 | 0.0038 | 0.0076 | 0.0244 | 0.0344 | 0.0337 | 0.0485 | 0.8443 | 6 | 8 | 9 | 10 | 11 | 13 | 17 | 52 | 137 | 0.1781 | 7.69 | 3.150 | 0.7073 | 12026.7 | 6360000 | 4770000000 | 4300000000000 | 0.4827 | 0.1912 | 0.0208 | 0.0043 | 0.0655 | 0.0157 | 0.1042 | 0.0386 | 0.1548 | 0.0815 | 0.1935 | 0.1302 | 0.1905 | 0.1774 | 0.1488 | 0.1245 | 0.0893 | 0.1660 | 0.0327 | 0.2618 | 0.0004 | 0.0007 | 0.0004 | 0.0018 | 0.0011 | 0.0036 | 0.0042 | 0.0075 | 0.0229 | 0.0220 | 0.0362 | 0.0341 | 0.0320 | 0.0242 | 0.0526 | 0.0512 | 0.8502 | 0.8550 | 0.0000 | 0.0000 | 0.0022 | 0.0019 | 0.0044 | 0.0033 | 0.0079 | 0.0071 | 0.0271 | 0.0288 | 0.0411 | 0.0506 | 0.0389 | 0.0378 | 0.0599 | 0.0624 | 0.8186 | 0.8080 | 0.0000 | 0.0012 | 0.0032 | 0.0085 | 0.0263 | 0.0388 | 0.0324 | 0.0599 | 0.8297 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 566 | 807 | | 4751 | 7725 | 404.9 | 192.17 | 127.70 | 196.98 | 142 | 186 | 268 | 341 | 396 | 464 | 540 | 611 | 670 | 0.1111 | 858 | 1.078 | 54.04 | 18.87 | 1 | 0.0280 | 133 | 0.0027 | 8.16 | 6.352 | 0.3795 | 200834.0 | 112000000 | 66500000000 | 41200000000000 | 0.3420 | 0.2744 | 0.0000 | 0.0005 | 0.0008 | 0.0005 | 0.0016 | 0.0005 | 0.0219 | 0.0064 | 0.0926 | 0.0401 | 0.1300 | 0.0724 | 0.1024 | 0.0519 | 0.1446 | 0.0738 | 0.5061 | 0.7540 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0003 | 0.0189 | 0.0153 | 0.0314 | 0.0269 | 0.0245 | 0.0136 | 0.0453 | 0.0266 | 0.8762 | 0.9173 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0011 | 0.0008 | 0.0050 | 0.0111 | 0.0296 | 0.0325 | 0.0369 | 0.0507 | 0.0335 | 0.0428 | 0.0464 | 0.0642 | 0.8475 | 0.7971 | 0.0000 | 0.0004 | 0.0000 | 0.0104 | 0.0265 | 0.0370 | 0.0313 | 0.0487 | 0.8456 | 7 | 9 | 11 | 16 | 28 | 63 | 121 | 222 | 412 | 0.0706 | 13.58 | 4.145 | 0.5200 | 55103.2 | 34600000 | 26500000000 | 23100000000000 | 0.6752 | 0.0630 | 0.0314 | 0.0009 | 0.1458 | 0.0204 | 0.2288 | 0.0814 | 0.1513 | 0.1230 | 0.1439 | 0.1748 | 0.1328 | 0.1832 | 0.0627 | 0.1221 | 0.0424 | 0.1240 | 0.0609 | 0.1702 | 0.0008 | 0.0000 | 0.0008 | 0.0003 | 0.0020 | 0.0007 | 0.0106 | 0.0115 | 0.0701 | 0.0687 | 0.1133 | 0.0965 | 0.0830 | 0.0767 | 0.1251 | 0.1154 | 0.5943 | 0.6302 | 0.0015 | 0.0000 | 0.0035 | 0.0028 | 0.0095 | 0.0084 | 0.0160 | 0.0302 | 0.0845 | 0.0878 | 0.1191 | 0.1270 | 0.1046 | 0.1079 | 0.1251 | 0.1208 | 0.5363 | 0.5151 | 0.0000 | 0.0013 | 0.0013 | 0.0191 | 0.0756 | 0.1250 | 0.0894 | 0.1299 | 0.5583 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 883 | 333 | | 6557 | 23757 | 237.9 | 49.19 | 167.48 | 247.49 | 178 | 194 | 208 | 219 | 232 | 246 | 261 | 279 | 306 | 0.0424 | 1007 | 0.712 | 125.45 | 28.02 | 1 | 0.0450 | 295 | 0.0009 | 51.46 | 7.234 | 0.1754 | 59019.4 | 15300000 | 4100000000 | 1150000000000 | 0.4457 | 0.2085 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0056 | 0.0002 | 0.0195 | 0.0010 | 0.0674 | 0.0163 | 0.1393 | 0.0371 | 0.1433 | 0.0322 | 0.1613 | 0.0570 | 0.4629 | 0.8563 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0061 | 0.0002 | 0.0308 | 0.0103 | 0.0701 | 0.0231 | 0.0660 | 0.0135 | 0.0840 | 0.0266 | 0.7414 | 0.9264 | 0.0026 | 0.0174 | 0.0141 | 0.0208 | 0.0132 | 0.0590 | 0.0695 | 0.1042 | 0.1240 | 0.1979 | 0.1803 | 0.1736 | 0.1152 | 0.1285 | 0.1495 | 0.1250 | 0.3316 | 0.1736 | 0.0013 | 0.0020 | 0.0073 | 0.0295 | 0.0809 | 0.1283 | 0.1037 | 0.1332 | 0.5138 | 10 | 11 | 13 | 15 | 22 | 70 | 185 | 328 | 546 | 0.0818 | 47.97 | 5.085 | 0.5273 | 89297.6 | 63700000 | 53300000000 | 49900000000000 | 0.5956 | 0.0948 | 0.0674 | 0.0040 | 0.2566 | 0.0182 | 0.3191 | 0.1656 | 0.1332 | 0.1895 | 0.1118 | 0.2077 | 0.0683 | 0.1749 | 0.0238 | 0.1020 | 0.0132 | 0.0814 | 0.0066 | 0.0567 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0008 | 0.0079 | 0.0064 | 0.0468 | 0.0389 | 0.0815 | 0.0785 | 0.0589 | 0.0508 | 0.0832 | 0.0748 | 0.7206 | 0.7498 | 0.0003 | 0.0000 | 0.0012 | 0.0024 | 0.0026 | 0.0046 | 0.0111 | 0.0124 | 0.0508 | 0.0535 | 0.0996 | 0.1030 | 0.0647 | 0.0701 | 0.0889 | 0.0964 | 0.6808 | 0.6577 | 0.0001 | 0.0012 | 0.0017 | 0.0109 | 0.0482 | 0.0875 | 0.0665 | 0.0853 | 0.6985 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 600 | | 4616 | 7928 | 344.2 | 66.06 | 265.90 | 254.61 | 259 | 286 | 308 | 325 | 341 | 359 | 377 | 401 | 435 | 0.1043 | 827 | 1.180 | 138.18 | 54.34 | 1 | 0.0782 | 361 | 0.0012 | 25.73 | 6.964 | 0.2269 | 122856.0 | 45400000 | 17300000000 | 6770000000000 | 0.4140 | 0.2347 | 0.0009 | 0.0000 | 0.0025 | 0.0002 | 0.0041 | 0.0002 | 0.0173 | 0.0013 | 0.0447 | 0.0183 | 0.0676 | 0.0359 | 0.0711 | 0.0219 | 0.1101 | 0.0415 | 0.6818 | 0.8807 | 0.0005 | 0.0000 | 0.0015 | 0.0000 | 0.0020 | 0.0000 | 0.0077 | 0.0007 | 0.0197 | 0.0159 | 0.0277 | 0.0303 | 0.0289 | 0.0135 | 0.0451 | 0.0266 | 0.8668 | 0.9131 | 0.0028 | 0.0000 | 0.0041 | 0.0000 | 0.0180 | 0.0000 | 0.0511 | 0.0000 | 0.0898 | 0.0000 | 0.1367 | 0.0000 | 0.1450 | 0.0000 | 0.1257 | 0.0000 | 0.4268 | 0.0000 | 0.0013 | 0.0031 | 0.0071 | 0.0205 | 0.0361 | 0.0672 | 0.0828 | 0.1033 | 0.6785 | 30 | 47 | 84 | 143 | 199 | 254 | 331 | 426 | 605 | 0.0066 | 47.91 | 6.596 | 0.3097 | 135523.0 | 96800000 | 84600000000 | 83800000000000 | 0.5314 | 0.1336 | 0.0148 | 0.0008 | 0.0818 | 0.0076 | 0.2167 | 0.0239 | 0.1528 | 0.0725 | 0.1730 | 0.1457 | 0.1302 | 0.1803 | 0.1005 | 0.1489 | 0.0733 | 0.1636 | 0.0569 | 0.2568 | 0.0000 | 0.0000 | 0.0011 | 0.0007 | 0.0061 | 0.0013 | 0.0143 | 0.0088 | 0.0586 | 0.0424 | 0.1040 | 0.0805 | 0.0828 | 0.0621 | 0.1157 | 0.0988 | 0.6175 | 0.7053 | 0.0008 | 0.0010 | 0.0016 | 0.0075 | 0.0076 | 0.0139 | 0.0298 | 0.0378 | 0.0953 | 0.0925 | 0.1460 | 0.1492 | 0.0973 | 0.1089 | 0.1375 | 0.1318 | 0.4841 | 0.4575 | 0.0003 | 0.0016 | 0.0046 | 0.0178 | 0.0753 | 0.1358 | 0.0976 | 0.1289 | 0.5381 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 307 | 284 | | 4454 | 15705 | 541.8 | 126.10 | 114.66 | 191.51 | 395 | 434 | 463 | 491 | 521 | 551 | 591 | 651 | 728 | 0.0554 | 870 | 1.060 | 102.88 | 27.59 | 2 | 0.0534 | 238 | 0.0008 | 82.33 | 7.369 | 0.1665 | 309466.0 | 186000000 | 118000000000 | 78000000000000 | 0.4066 | 0.2345 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0005 | 0.0157 | 0.0027 | 0.0737 | 0.0261 | 0.1377 | 0.0438 | 0.1448 | 0.0443 | 0.1534 | 0.0597 | 0.4611 | 0.8229 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0056 | 0.0002 | 0.0407 | 0.0161 | 0.0709 | 0.0258 | 0.0709 | 0.0192 | 0.0895 | 0.0269 | 0.7210 | 0.9117 | 0.0022 | 0.0032 | 0.0000 | 0.0160 | 0.0078 | 0.0415 | 0.0526 | 0.0927 | 0.0973 | 0.1629 | 0.1353 | 0.1502 | 0.0839 | 0.1086 | 0.1074 | 0.1438 | 0.5134 | 0.2812 | 0.0000 | 0.0031 | 0.0062 | 0.0333 | 0.0868 | 0.1149 | 0.1004 | 0.1108 | 0.5445 | 5 | 7 | 8 | 10 | 11 | 17 | 98 | 220 | 400 | 0.1818 | 28.75 | 4.115 | 0.6043 | 49820.4 | 29100000 | 19900000000 | 15300000000000 | 0.3528 | 0.2965 | 0.0222 | 0.0027 | 0.0974 | 0.0054 | 0.2530 | 0.0467 | 0.2085 | 0.0916 | 0.1880 | 0.2163 | 0.1333 | 0.2720 | 0.0496 | 0.1517 | 0.0222 | 0.1086 | 0.0256 | 0.1050 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0010 | 0.0002 | 0.0025 | 0.0028 | 0.0223 | 0.0206 | 0.0377 | 0.0307 | 0.0289 | 0.0256 | 0.0466 | 0.0365 | 0.8607 | 0.8834 | 0.0005 | 0.0003 | 0.0002 | 0.0005 | 0.0002 | 0.0005 | 0.0059 | 0.0071 | 0.0334 | 0.0374 | 0.0541 | 0.0695 | 0.0498 | 0.0450 | 0.0636 | 0.0730 | 0.7923 | 0.7666 | 0.0002 | 0.0000 | 0.0004 | 0.0042 | 0.0271 | 0.0491 | 0.0391 | 0.0560 | 0.8237 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 665 | 315 | | 3881 | 7921 | 606.2 | 94.41 | 68.43 | 170.19 | 472 | 541 | 568 | 588 | 606 | 629 | 660 | 694 | 726 | 0.0917 | 726 | 0.976 | 112.07 | 42.38 | 2 | 0.0825 | 320 | 0.0014 | 32.18 | 6.910 | 0.2353 | 376420.0 | 239000000 | 154000000000 | 101000000000000 | 0.4392 | 0.1933 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0005 | 0.0345 | 0.0169 | 0.0495 | 0.0301 | 0.0505 | 0.0161 | 0.0697 | 0.0270 | 0.7890 | 0.9095 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0005 | 0.0212 | 0.0169 | 0.0256 | 0.0301 | 0.0206 | 0.0161 | 0.0317 | 0.0270 | 0.8986 | 0.9095 | 0.0054 | 0.0000 | 0.0161 | 0.0000 | 0.0215 | 0.0000 | 0.0538 | 0.0000 | 0.1048 | 0.0000 | 0.1532 | 0.0000 | 0.1183 | 0.0000 | 0.1263 | 0.0000 | 0.4005 | 0.0000 | 0.0031 | 0.0031 | 0.0097 | 0.0219 | 0.0429 | 0.0566 | 0.0536 | 0.0929 | 0.7163 | 5 | 6 | 7 | 9 | 10 | 11 | 14 | 30 | 209 | 0.1903 | 6.63 | 2.602 | 0.6219 | 33642.3 | 23500000 | 18600000000 | 16100000000000 | 0.5469 | 0.1234 | 0.0143 | 0.0118 | 0.2071 | 0.0059 | 0.2500 | 0.0710 | 0.2357 | 0.1154 | 0.2571 | 0.2308 | 0.0286 | 0.2337 | 0.0071 | 0.1834 | 0.0000 | 0.1065 | 0.0000 | 0.0414 | 0.0000 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0050 | 0.0119 | 0.0114 | 0.0500 | 0.0456 | 0.0738 | 0.0777 | 0.0484 | 0.0428 | 0.0745 | 0.0720 | 0.7407 | 0.7418 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0009 | 0.0089 | 0.0132 | 0.0526 | 0.0545 | 0.0847 | 0.0771 | 0.0455 | 0.0526 | 0.0794 | 0.0808 | 0.7279 | 0.7209 | 0.0000 | 0.0000 | 0.0017 | 0.0093 | 0.0499 | 0.0854 | 0.0448 | 0.0761 | 0.7327 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1257 | 588 | | 6871 | 2051 | 137.3 | 25.65 | 90.04 | 55.86 | 104 | 115 | 123 | 130 | 137 | 144 | 150 | 159 | 170 | 0.3667 | 752 | 0.924 | 92.78 | 24.76 | 1 | 0.0342 | 235 | 0.0024 | 19.20 | 6.305 | 0.2542 | 19504.3 | 2860000 | 432000000 | 67100000000 | 0.4703 | 0.1831 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0058 | 0.0004 | 0.0210 | 0.0004 | 0.0599 | 0.0142 | 0.1283 | 0.0298 | 0.1440 | 0.0322 | 0.2039 | 0.0594 | 0.4358 | 0.8634 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0026 | 0.0004 | 0.0066 | 0.0001 | 0.0250 | 0.0117 | 0.0591 | 0.0222 | 0.0521 | 0.0126 | 0.0901 | 0.0273 | 0.7638 | 0.9256 | 0.0138 | 0.0690 | 0.0324 | 0.0621 | 0.0482 | 0.1724 | 0.1455 | 0.2621 | 0.1888 | 0.1862 | 0.1642 | 0.1517 | 0.1445 | 0.0759 | 0.1259 | 0.0207 | 0.1367 | 0.0000 | 0.0006 | 0.0048 | 0.0097 | 0.0311 | 0.0829 | 0.1268 | 0.1317 | 0.1622 | 0.4503 | 25 | 40 | 54 | 69 | 83 | 97 | 113 | 133 | 160 | 0.0056 | 13.56 | 5.596 | 0.3618 | 11225.5 | 1750000 | 329000000 | 72100000000 | 0.5016 | 0.1610 | 0.0194 | 0.0010 | 0.1282 | 0.0104 | 0.2039 | 0.0604 | 0.1942 | 0.1093 | 0.1515 | 0.1894 | 0.1612 | 0.2362 | 0.0971 | 0.1592 | 0.0291 | 0.1228 | 0.0155 | 0.1113 | 0.0008 | 0.0007 | 0.0067 | 0.0028 | 0.0193 | 0.0104 | 0.0469 | 0.0291 | 0.1182 | 0.0992 | 0.1869 | 0.1881 | 0.1090 | 0.1013 | 0.1534 | 0.1367 | 0.3588 | 0.4316 | 0.0074 | 0.0125 | 0.0251 | 0.0250 | 0.0457 | 0.0813 | 0.0959 | 0.1479 | 0.1504 | 0.1583 | 0.2021 | 0.1813 | 0.1239 | 0.1458 | 0.1431 | 0.1333 | 0.2065 | 0.1146 | 0.0022 | 0.0108 | 0.0390 | 0.0683 | 0.1354 | 0.1788 | 0.1365 | 0.1560 | 0.2730 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 173 | 580 | | 3314 | 11955 | 517.2 | 91.88 | 119.57 | 243.85 | 373 | 433 | 487 | 512 | 531 | 550 | 573 | 598 | 624 | 0.0613 | 733 | 0.446 | 104.39 | 23.32 | 3 | 0.0993 | 329 | 0.0010 | 41.90 | 7.124 | 0.2030 | 275939.0 | 151000000 | 84400000000 | 48000000000000 | 0.4375 | 0.1965 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0017 | 0.0003 | 0.0071 | 0.0009 | 0.0384 | 0.0163 | 0.0744 | 0.0359 | 0.0660 | 0.0157 | 0.0994 | 0.0273 | 0.7101 | 0.9033 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0000 | 0.0003 | 0.0014 | 0.0009 | 0.0206 | 0.0163 | 0.0343 | 0.0359 | 0.0220 | 0.0157 | 0.0354 | 0.0273 | 0.8851 | 0.9033 | 0.0134 | 0.0000 | 0.0160 | 0.0000 | 0.0428 | 0.0000 | 0.0856 | 0.0000 | 0.1096 | 0.0000 | 0.1791 | 0.0000 | 0.1123 | 0.0000 | 0.1417 | 0.0000 | 0.2995 | 0.0000 | 0.0005 | 0.0042 | 0.0094 | 0.0141 | 0.0381 | 0.0522 | 0.0637 | 0.0914 | 0.7262 | 9 | 12 | 14 | 16 | 21 | 31 | 57 | 130 | 371 | 0.1465 | 4.98 | 3.299 | 0.6421 | 73753.8 | 72700000 | 87000000000 | 116000000000000 | 0.4905 | 0.1557 | 0.0398 | 0.0000 | 0.1155 | 0.0121 | 0.1474 | 0.0864 | 0.1932 | 0.1021 | 0.1972 | 0.1690 | 0.1554 | 0.1820 | 0.0777 | 0.1328 | 0.0498 | 0.1235 | 0.0239 | 0.1922 | 0.0000 | 0.0000 | 0.0025 | 0.0012 | 0.0051 | 0.0044 | 0.0108 | 0.0097 | 0.0375 | 0.0400 | 0.0563 | 0.0512 | 0.0512 | 0.0465 | 0.0776 | 0.0787 | 0.7589 | 0.7684 | 0.0000 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0028 | 0.0119 | 0.0127 | 0.0419 | 0.0409 | 0.0608 | 0.0682 | 0.0591 | 0.0564 | 0.0784 | 0.0804 | 0.7466 | 0.7377 | 0.0008 | 0.0008 | 0.0028 | 0.0097 | 0.0399 | 0.0565 | 0.0480 | 0.0871 | 0.7543 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 835 | 668 | | 9436 | 26949 | 509.0 | 119.52 | 167.87 | 203.60 | 373 | 412 | 441 | 467 | 495 | 522 | 555 | 598 | 668 | 0.0413 | 1112 | 0.662 | 166.43 | 45.61 | 1 | 0.0520 | 491 | 0.0006 | 62.28 | 7.676 | 0.1552 | 273329.0 | 155000000 | 92900000000 | 58900000000000 | 0.4414 | 0.2158 | 0.0005 | 0.0000 | 0.0010 | 0.0001 | 0.0045 | 0.0001 | 0.0160 | 0.0016 | 0.0599 | 0.0173 | 0.1253 | 0.0382 | 0.1333 | 0.0410 | 0.1696 | 0.0533 | 0.4898 | 0.8484 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0056 | 0.0004 | 0.0284 | 0.0114 | 0.0665 | 0.0214 | 0.0584 | 0.0205 | 0.0867 | 0.0273 | 0.7535 | 0.9190 | 0.0030 | 0.0000 | 0.0095 | 0.0141 | 0.0233 | 0.0194 | 0.0531 | 0.0952 | 0.1103 | 0.1411 | 0.1455 | 0.1711 | 0.0960 | 0.0935 | 0.1306 | 0.1323 | 0.4287 | 0.3333 | 0.0002 | 0.0045 | 0.0079 | 0.0271 | 0.0857 | 0.1202 | 0.0911 | 0.1114 | 0.5519 | 8 | 11 | 17 | 36 | 77 | 141 | 218 | 316 | 466 | 0.0551 | 40.07 | 5.701 | 0.4557 | 69631.7 | 39300000 | 26800000000 | 21000000000000 | 0.4485 | 0.1832 | 0.0434 | 0.0008 | 0.1902 | 0.0126 | 0.2802 | 0.1166 | 0.1517 | 0.1613 | 0.1292 | 0.2019 | 0.0888 | 0.1955 | 0.0589 | 0.1175 | 0.0323 | 0.0958 | 0.0254 | 0.0979 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0093 | 0.0067 | 0.0549 | 0.0483 | 0.1006 | 0.0833 | 0.0610 | 0.0527 | 0.0967 | 0.0874 | 0.6773 | 0.7214 | 0.0002 | 0.0004 | 0.0009 | 0.0003 | 0.0012 | 0.0017 | 0.0175 | 0.0227 | 0.0800 | 0.0909 | 0.1203 | 0.1382 | 0.0793 | 0.0819 | 0.1150 | 0.1299 | 0.5857 | 0.5341 | 0.0000 | 0.0002 | 0.0021 | 0.0123 | 0.0723 | 0.1039 | 0.0750 | 0.1098 | 0.6245 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1191 | 273 | | 5225 | 11025 | 340.7 | 62.23 | 307.66 | 490.68 | 248 | 283 | 309 | 330 | 349 | 367 | 381 | 396 | 416 | 0.0786 | 867 | 0.925 | 79.06 | 24.04 | 4 | 0.0404 | 211 | 0.0014 | 23.53 | 6.846 | 0.2524 | 119949.0 | 43400000 | 16100000000 | 6080000000000 | 0.4363 | 0.2015 | 0.0005 | 0.0000 | 0.0024 | 0.0000 | 0.0052 | 0.0004 | 0.0144 | 0.0012 | 0.0415 | 0.0155 | 0.0735 | 0.0306 | 0.0749 | 0.0196 | 0.1045 | 0.0333 | 0.6830 | 0.8994 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0014 | 0.0004 | 0.0046 | 0.0012 | 0.0191 | 0.0153 | 0.0353 | 0.0304 | 0.0290 | 0.0163 | 0.0376 | 0.0273 | 0.8719 | 0.9093 | 0.0076 | 0.0000 | 0.0291 | 1.0000 | 0.0443 | 0.0000 | 0.0581 | 0.0000 | 0.1407 | 0.0000 | 0.1361 | 0.0000 | 0.1300 | 0.0000 | 0.1529 | 0.0000 | 0.3012 | 0.0000 | 0.0007 | 0.0021 | 0.0070 | 0.0115 | 0.0369 | 0.0518 | 0.0539 | 0.0869 | 0.7493 | 8 | 10 | 12 | 16 | 25 | 61 | 277 | 673 | 1103 | 0.0635 | 24.60 | 4.331 | 0.4441 | 335399.0 | 461000000 | 722000000000 | 1.24E+15 | 0.5061 | 0.1164 | 0.0746 | 0.0000 | 0.2293 | 0.0218 | 0.2541 | 0.1592 | 0.1602 | 0.1687 | 0.1409 | 0.2082 | 0.0829 | 0.1891 | 0.0304 | 0.0898 | 0.0193 | 0.0939 | 0.0083 | 0.0694 | 0.0000 | 0.0000 | 0.0006 | 0.0006 | 0.0038 | 0.0011 | 0.0065 | 0.0047 | 0.0332 | 0.0356 | 0.0632 | 0.0601 | 0.0397 | 0.0361 | 0.0585 | 0.0593 | 0.7947 | 0.8025 | 0.0003 | 0.0003 | 0.0007 | 0.0003 | 0.0023 | 0.0017 | 0.0056 | 0.0055 | 0.0391 | 0.0464 | 0.0687 | 0.0695 | 0.0444 | 0.0488 | 0.0736 | 0.0768 | 0.7653 | 0.7506 | 0.0003 | 0.0012 | 0.0016 | 0.0068 | 0.0346 | 0.0626 | 0.0392 | 0.0688 | 0.7849 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 406 | 806 | | 3869 | 9909 | 688.7 | 123.70 | 61.45 | 130.52 | 523 | 588 | 635 | 670 | 698 | 722 | 743 | 770 | 857 | 0.0768 | 761 | 1.128 | 89.45 | 33.12 | 2 | 0.0605 | 234 | 0.0009 | 60.15 | 7.294 | 0.1719 | 489556.0 | 358000000 | 269000000000 | 207000000000000 | 0.3551 | 0.2759 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0039 | 0.0005 | 0.0389 | 0.0191 | 0.0470 | 0.0343 | 0.0473 | 0.0252 | 0.0666 | 0.0433 | 0.7950 | 0.8776 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0021 | 0.0005 | 0.0251 | 0.0187 | 0.0338 | 0.0305 | 0.0311 | 0.0174 | 0.0429 | 0.0274 | 0.8639 | 0.9056 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0217 | 0.0000 | 0.0522 | 0.0000 | 0.0435 | 0.0000 | 0.0783 | 0.0000 | 0.0696 | 0.0000 | 0.7348 | 0.0000 | 0.0005 | 0.0014 | 0.0048 | 0.0144 | 0.0393 | 0.0672 | 0.0561 | 0.0859 | 0.7303 | 6 | 8 | 9 | 10 | 11 | 13 | 21 | 63 | 186 | 0.1948 | 6.58 | 2.831 | 0.6506 | 20808.7 | 11500000 | 7940000000 | 6280000000000 | 0.3866 | 0.2159 | 0.0387 | 0.0072 | 0.1613 | 0.0273 | 0.2355 | 0.1164 | 0.2065 | 0.1193 | 0.1839 | 0.1379 | 0.0903 | 0.1897 | 0.0548 | 0.1149 | 0.0194 | 0.1379 | 0.0097 | 0.1494 | 0.0005 | 0.0000 | 0.0005 | 0.0008 | 0.0009 | 0.0004 | 0.0147 | 0.0132 | 0.0372 | 0.0371 | 0.0689 | 0.0556 | 0.0358 | 0.0342 | 0.0611 | 0.0671 | 0.7804 | 0.7917 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0032 | 0.0017 | 0.0118 | 0.0121 | 0.0428 | 0.0537 | 0.0707 | 0.0779 | 0.0386 | 0.0467 | 0.0739 | 0.0848 | 0.7590 | 0.7213 | 0.0005 | 0.0005 | 0.0020 | 0.0125 | 0.0435 | 0.0659 | 0.0390 | 0.0649 | 0.7712 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 666 | 842 | | 12884 | 27221 | 219.0 | 58.92 | 118.73 | 205.47 | 152 | 171 | 185 | 199 | 212 | 227 | 245 | 268 | 298 | 0.0499 | 1359 | 0.808 | 193.62 | 44.05 | 2 | 0.0354 | 456 | 0.0008 | 46.64 | 7.460 | 0.1768 | 51441.8 | 12900000 | 3430000000 | 964000000000 | 0.4180 | 0.2281 | 0.0003 | 0.0001 | 0.0020 | 0.0000 | 0.0075 | 0.0004 | 0.0271 | 0.0027 | 0.0783 | 0.0206 | 0.1403 | 0.0412 | 0.1412 | 0.0459 | 0.1709 | 0.0684 | 0.4325 | 0.8207 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0023 | 0.0000 | 0.0103 | 0.0014 | 0.0303 | 0.0115 | 0.0505 | 0.0181 | 0.0596 | 0.0180 | 0.0775 | 0.0275 | 0.7681 | 0.9236 | 0.0028 | 0.0068 | 0.0028 | 0.0184 | 0.0137 | 0.0261 | 0.0439 | 0.0812 | 0.0847 | 0.1285 | 0.1612 | 0.1865 | 0.1135 | 0.0889 | 0.1377 | 0.1449 | 0.4398 | 0.3188 | 0.0017 | 0.0044 | 0.0094 | 0.0269 | 0.0584 | 0.0906 | 0.0952 | 0.1178 | 0.5957 | 12 | 14 | 16 | 19 | 23 | 35 | 81 | 186 | 369 | 0.1090 | 28.98 | 4.298 | 0.6029 | 56311.6 | 43400000 | 43600000000 | 52400000000000 | 0.4887 | 0.1540 | 0.1380 | 0.0057 | 0.3027 | 0.0505 | 0.2534 | 0.2149 | 0.1170 | 0.1937 | 0.0888 | 0.2013 | 0.0605 | 0.1398 | 0.0282 | 0.0765 | 0.0105 | 0.0629 | 0.0008 | 0.0547 | 0.0000 | 0.0004 | 0.0018 | 0.0008 | 0.0016 | 0.0015 | 0.0149 | 0.0108 | 0.0607 | 0.0575 | 0.0912 | 0.0799 | 0.0683 | 0.0568 | 0.1015 | 0.0892 | 0.6600 | 0.7031 | 0.0005 | 0.0000 | 0.0008 | 0.0012 | 0.0040 | 0.0058 | 0.0208 | 0.0226 | 0.0784 | 0.0804 | 0.1103 | 0.1258 | 0.0842 | 0.0911 | 0.1132 | 0.1227 | 0.5879 | 0.5503 | 0.0004 | 0.0011 | 0.0027 | 0.0160 | 0.0680 | 0.1060 | 0.0721 | 0.1158 | 0.6178 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 989 | 569 | | 11363 | 17154 | 435.1 | 102.14 | 100.15 | 106.92 | 319 | 350 | 374 | 396 | 420 | 445 | 475 | 519 | 577 | 0.0642 | 1102 | 1.214 | 111.97 | 45.88 | 1 | 0.0259 | 294 | 0.0008 | 45.10 | 7.457 | 0.1791 | 199761.0 | 96800000 | 49400000000 | 26500000000000 | 0.4356 | 0.2162 | 0.0004 | 0.0001 | 0.0023 | 0.0001 | 0.0049 | 0.0006 | 0.0187 | 0.0024 | 0.0547 | 0.0168 | 0.1228 | 0.0359 | 0.1224 | 0.0361 | 0.1532 | 0.0537 | 0.5207 | 0.8544 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0001 | 0.0074 | 0.0009 | 0.0262 | 0.0104 | 0.0589 | 0.0186 | 0.0605 | 0.0168 | 0.0788 | 0.0275 | 0.7659 | 0.9258 | 0.0027 | 0.0014 | 0.0063 | 0.0068 | 0.0094 | 0.0315 | 0.0367 | 0.0876 | 0.0823 | 0.1231 | 0.1360 | 0.1737 | 0.0922 | 0.1081 | 0.1128 | 0.1231 | 0.5217 | 0.3447 | 0.0010 | 0.0012 | 0.0068 | 0.0319 | 0.0806 | 0.1097 | 0.0930 | 0.1123 | 0.5635 | 7 | 11 | 20 | 37 | 62 | 94 | 132 | 180 | 248 | 0.0392 | 11.55 | 4.988 | 0.4732 | 21460.8 | 6340000 | 2300000000 | 971000000000 | 0.5515 | 0.1124 | 0.0581 | 0.0039 | 0.2164 | 0.0200 | 0.2885 | 0.1377 | 0.1593 | 0.1383 | 0.1259 | 0.1997 | 0.0867 | 0.1917 | 0.0344 | 0.1180 | 0.0237 | 0.1032 | 0.0070 | 0.0874 | 0.0001 | 0.0001 | 0.0005 | 0.0005 | 0.0012 | 0.0003 | 0.0130 | 0.0092 | 0.0667 | 0.0520 | 0.1087 | 0.0943 | 0.0812 | 0.0656 | 0.1186 | 0.1022 | 0.6099 | 0.6759 | 0.0005 | 0.0012 | 0.0010 | 0.0029 | 0.0045 | 0.0074 | 0.0218 | 0.0286 | 0.0939 | 0.1036 | 0.1590 | 0.1785 | 0.0997 | 0.1088 | 0.1431 | 0.1573 | 0.4763 | 0.4118 | 0.0003 | 0.0006 | 0.0018 | 0.0174 | 0.0781 | 0.1316 | 0.0944 | 0.1376 | 0.5381 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 680 | 102 | | 4304 | 6744 | 541.8 | 144.02 | 32.62 | 45.34 | 329 | 395 | 450 | 516 | 566 | 606 | 638 | 670 | 705 | 0.0948 | 639 | 0.542 | 117.00 | 26.02 | 1 | 0.0853 | 367 | 0.0008 | 32.43 | 7.325 | 0.2185 | 314288.0 | 192000000 | 122000000000 | 80400000000000 | 0.3875 | 0.2444 | 0.0010 | 0.0000 | 0.0025 | 0.0003 | 0.0069 | 0.0003 | 0.0212 | 0.0022 | 0.0562 | 0.0210 | 0.0877 | 0.0339 | 0.0946 | 0.0234 | 0.1252 | 0.0358 | 0.6047 | 0.8831 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0006 | 0.0003 | 0.0044 | 0.0015 | 0.0197 | 0.0172 | 0.0292 | 0.0288 | 0.0251 | 0.0175 | 0.0368 | 0.0275 | 0.8842 | 0.9070 | 0.0000 | 0.0000 | 0.0080 | 0.0000 | 0.0187 | 0.0000 | 0.0276 | 0.0000 | 0.0480 | 0.0000 | 0.0730 | 0.0000 | 0.0747 | 0.0000 | 0.1103 | 0.0000 | 0.6397 | 1.0000 | 0.0000 | 0.0013 | 0.0017 | 0.0055 | 0.0233 | 0.0355 | 0.0364 | 0.0508 | 0.8455 | 8 | 9 | 11 | 12 | 15 | 18 | 26 | 44 | 83 | 0.2567 | 1.27 | 2.377 | 0.7837 | 3119.9 | 589671 | 172000000 | 67600000000 | 0.6419 | 0.0827 | 0.0252 | 0.0246 | 0.1124 | 0.0419 | 0.1550 | 0.0583 | 0.2190 | 0.0887 | 0.1725 | 0.1297 | 0.1570 | 0.1478 | 0.1066 | 0.1445 | 0.0504 | 0.1650 | 0.0019 | 0.1995 | 0.0035 | 0.0115 | 0.0080 | 0.0167 | 0.0141 | 0.0199 | 0.0251 | 0.0267 | 0.0693 | 0.0554 | 0.1065 | 0.0940 | 0.0749 | 0.0737 | 0.0965 | 0.0992 | 0.6020 | 0.6029 | 0.0034 | 0.0031 | 0.0054 | 0.0085 | 0.0075 | 0.0124 | 0.0360 | 0.0325 | 0.0658 | 0.0688 | 0.1126 | 0.1145 | 0.0855 | 0.0828 | 0.1119 | 0.1121 | 0.5719 | 0.5654 | 0.0012 | 0.0070 | 0.0153 | 0.0282 | 0.0728 | 0.1045 | 0.0752 | 0.1057 | 0.5901 |